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https://www.readbyqxmd.com/read/29775862/identification-and-functional-characterization-of-a-max2-ortholog-from-switchgrass-panicum-virgatum-l
#1
Tingting Cheng, Donghua Wang, Yongfeng Wang, Shumeng Zhang, Chao Zhang, Shudong Liu, Yajun Xi, Fengli Sun
Switchgrass (Panicum virgatum L.) is a sustainable cellulosic energy crop with high biomass yield on marginal soils. Tillering, an important agronomic characteristic related to biomass production in gramineous plants, is regulated by complex interacting factors, such as plant hormones. Strigolactones (SLs) comprise a novel class of plant hormones that inhibit shoot branching. The MORE AXILLARY GROWTH2 (MAX2)/DWARF 3 (D3)/RAMOSUS (RMS4) genes encode proteins involved in the SL signaling pathway in various plants...
May 15, 2018: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/29774313/echoes-from-the-40-th-annual-san-antonio-breast-cancer-symposium-2017
#2
Bekir Kuru
The Annual San Antonio Symposium was held on 5-9, December, 2017 in San Antonio, Texas, USA (1). As expected, many new studies were presented for the first time at the sessions. The unofficial opening lecture in my point of view was given on locoregional recurrence by Monica Morrow from MSKCC, New York. As always, Morrow's lecture on "Challenges in the surgical management of locoregional recurrence" attracted great interest. The other prominent conferences were given on "Individualizing Management of the Axillary Nodes" by Tari A...
April 2018: European Journal of Breast Health
https://www.readbyqxmd.com/read/29773888/antitumor-effect-of-axitinib-combined-with-dopamine-and-pk-pd-modeling-in-the-treatment-of-human-breast-cancer-xenograft
#3
Yuan-Heng Ma, Si-Yuan Wang, Yu-Peng Ren, Jian Li, Ting-Jie Guo, Wei Lu, Tian-Yan Zhou
Rising evidence has shown the development of resistance to vascular endothelial growth factor receptor (VEGFR) inhibitors in the practices of cancer therapy. It is reported that the efficacy of axitinib (AX), a VEGFR inhibitor, is limited in the treatment of breast cancer as a single agent or in combination with other chemotherapeutic drugs due to the probability of rising population of cancer stem-like cells (CSCs) caused by AX. The present study evaluated the effect of dopamine (DA) improving AX's efficacy on MCF-7/ADR breast cancer in vitro and in vivo, and developed a pharmacokinetic-pharmacodynamic (PK-PD) model describing the in vivo experimental data and characterizing the interaction of effect between AX and DA...
May 17, 2018: Acta Pharmacologica Sinica
https://www.readbyqxmd.com/read/29773370/rheological-and-structural-properties-of-complex-arabinoxylans-from-plantago-ovata-seed-mucilage-under-non-gelled-conditions
#4
Long Yu, Gleb E Yakubov, Marta Martínez-Sanz, Elliot P Gilbert, Jason R Stokes
Two gel-forming arabinoxylan (AX) fractions with very similar linkage composition and molecular weight distributions have been isolated from Plantago ovata seed mucilage. Both isolated fractions have distinct gel properties attributed to differences in intermolecular hydrogen bonding. This study probes the effect of hydrogen bonding on molecular interactions of P. ovata AX fractions under non-gelled conditions achieved using a mild hydrogen bonding inhibitor, 0.2 M KOH. Chain conformation, relaxation dynamics and interactions between AX molecules are investigated using a combination of rheological techniques and small angle X-ray and neutron scattering...
August 1, 2018: Carbohydrate Polymers
https://www.readbyqxmd.com/read/29770850/ultrasound-measurements-of-axillary-recess-capsule-thickness-in-unilateral-frozen-shoulder-study-of-correlation-with-mri-measurements
#5
Du Hwan Kim, Chul-Hyun Cho, Duk Hyun Sung
OBJECTIVE: The aims of this study were to compare the ultrasound thickness of the affected axillary recess capsule (ARC) with that of the unaffected ARC in patients with frozen shoulder (FS), to analyze whether the ultrasound measurements of the ARC thickness correlate with those obtained using MRI, and to assess whether the ultrasound thickness of the ARC correlates with the patterns of range of motion limitation. MATERIALS AND METHODS: Forty-four patients with clinically diagnosed unilateral FS and MRI evaluation performed ultrasound measurement of ARC...
May 16, 2018: Skeletal Radiology
https://www.readbyqxmd.com/read/29770313/management-of-the-axilla-in-metaplastic-breast-carcinoma
#6
Brittany L Murphy, Robert T Fazzio, Tanya L Hoskin, Katrina N Glazebrook, Michael G Keeney, Elizabeth B Habermann, Tina J Hieken
Background: Metaplastic breast cancer (MBC), characterized by admixed epithelial, squamous or mesenchymal elements, constitutes <1% of breast cancers and has a poor prognosis but a paradoxically low reported rate of axillary lymph node (LN) involvement. Due to its rarity, data on appropriate axillary management is lacking, prompting this investigation of LN status and outcomes. Methods: We identified 41 MBC patients treated at our institution 2001-2011 who were followed for a median of 66 months...
April 2018: Gland Surgery
https://www.readbyqxmd.com/read/29770285/large-non-enhancing-breast-cancer-on-breast-magnetic-resonance-imaging-a-case-report
#7
Johannes Peters, Wei Che Tsai, Gudrun Peters
A 55-year-old female presented with vague symptoms in the lateral left breast. Digital breast tomosynthesis and breast ultrasound showed no focal lesion, and magnetic resonance imaging (MRI) was subsequently performed. No suspicious enhancement was seen on MRI; in particular, no suspicious lesion was seen in the area of clinical concern. In view of persisting focal mastalgia and vague parenchymal changes in the symptomatic area on repeat targeted ultrasound, a core biopsy was performed. Final pathology after left mastectomy with axillary clearance showed a 42 mm grade 2 invasive ductal carcinoma...
March 15, 2018: Curēus
https://www.readbyqxmd.com/read/29770221/risperidone-induced-type-2-diabetes-presenting-with-diabetic-ketoacidosis
#8
Clarissa Ern Hui Fang, Mohammed Faraz Rafey, Aine Cunningham, Sean F Dinneen, Francis M Finucane
A 28-year-old male presented with 2 days of vomiting and abdominal pain, preceded by 2 weeks of thirst, polyuria and polydipsia. He had recently started risperidone for obsessive-compulsive disorder. He reported a high dietary sugar intake and had a strong family history of type 2 diabetes mellitus (T2DM). On admission, he was tachycardic, tachypnoeic and drowsy with a Glasgow Coma Scale (GCS) of 10/15. We noted axillary acanthosis nigricans and obesity (BMI 33.2 kg/m2 ). Dipstick urinalysis showed ketonuria and glycosuria...
2018: Endocrinology, Diabetes & Metabolism Case Reports
https://www.readbyqxmd.com/read/29770184/human-body-odour-composites-are-not-perceived-more-positively-than-the-individual-samples
#9
Jitka Fialová, Agnieszka Sorokowska, S Craig Roberts, Lydie Kubicová, Jan Havlíček
It is well established that composite facial images are perceived as more attractive compared with individual images, suggesting a preference for heterozygosity. Similarly, there is evidence that preferences for body odours might be linked to heterozygosity. Here, we tested whether blending individual body odours into composites would follow a similar pattern as observed in the perception of faces. We collected axillary odour samples from 38 individuals, which were subsequently assessed individually and as composites of two ( N  = 19) or four ( N  = 9) body odours regarding their pleasantness, attractiveness and intensity...
May 2018: I-Perception
https://www.readbyqxmd.com/read/29769836/a-revision-of-the-cleptoparasitic-bee-genus-epeolus-latreille-for-nearctic-species-north-of-mexico-hymenoptera-apidae
#10
Thomas M Onuferko
Herein, the cleptoparasitic (cuckoo) bee genus Epeolus (Hymenoptera: Apidae) is revised for species occurring in North America, north of Mexico, and an updated checklist of all species known to occur in Canada and the United States of America is provided with comprehensive descriptions, diagnoses, and a single dichotomous key (using the same couplets for both sexes) to aid in their identification. To increase their recognition among North American naturalists, English common names are also proposed for all North American Epeolus ...
2018: ZooKeys
https://www.readbyqxmd.com/read/29768565/cat-scratch-disease-presenting-as-axillary-lymphadenopathy-and-a-palpable-benign-mammary-nodule-mimicking-a-carcinoma
#11
Larissa Cabral Marques, Kátia Pincerato, Adriana Akemi Yoshimura, Felipe Eduardo Martins Andrade, Alfredo Carlos Simões Dornellas de Barros
We present a case involving a 74-year-old woman with cat scratch disease characterized by an enlarged and hard axillary lymph node as well as a palpable breast nodule mimicking a carcinoma. The lymph node and the breast nodule were excised. The pathologic examinations revealed granulomatous lymphadenitis with gram-negative bacilli and an intraductal papilloma. Antibiotic therapy (azithromycin) was prescribed and the patient's clinical evolution was excellent.
March 2018: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/29766708/axillary-extramammary-paget-s-disease-on-lymphadenectomy-scar-for-melanoma-an-instance-of-immunocompromised-district
#12
Roberta Giuffrida, Francesco Borgia, Maria Lentini, Roberta Cardia, Serafinella P Cannavò
No abstract text is available yet for this article.
June 2018: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/29766409/where-youth-matters-clinicopathologic-characteristics-and-emerging-trends-in-treatment-and-outcomes-in-young-irish-women-with-breast-cancer
#13
Megan Greally, Jennifer Kielty, Geoffrey A Watson, Geoffrey Das, Christina Malouf, Lynda McSorley, Niamh Coleman, Cecily Quinn, Enda W McDermott, Giuseppe Gullo, John Crown, Ruth S Prichard, Catherine M Kelly, Janice M Walshe
BACKGROUND: Young women with breast cancer (YWBC) represent 7-12% of breast cancer diagnoses and ostensibly have more biologically aggressive subtypes with higher relapse and mortality rates. We studied the clinical and pathological characteristics in YWBC and examined how outcomes and treatment have evolved. METHODS: YWBC were identified from pathology databases at two tertiary centers. Patients were divided into two cohorts: those diagnosed from 2000 to 2005 (C1) and from 2006 to 2015 (C2)...
May 15, 2018: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/29765968/histopathological-evidence-of-the-efficacy-of-percutaneous-ethanol-injection-in-the-treatment-of-axillary-osmidrosis-a-promising-new-procedure
#14
Ali Asilian, Bahareh Abtahi-Naeini, Masoom Shahbazi
Axillary osmidrosis (AO) is a common disease, affecting patients psychologically and influencing their quality of life. The medical approach to AO remains controversial, ranging from conservative medical to surgical choices. We describe the successful treatment of AO and axillary hyperhidrosis (AH) using percutaneous ethanol injection (PEI) in a 30-year-old patient with AO and AH who did not respond to topical and systemic medication. We also describe the clinical efficacy of PEI by presenting our experience with histopathological evidence of necrosis of the sweat glands...
April 2018: Skin Appendage Disorders
https://www.readbyqxmd.com/read/29765965/dermoscopy-of-yellow-concretions-on-axillary-hair
#15
Jessica Cervantes, Robert J Johr, Antonella Tosti
No abstract text is available yet for this article.
April 2018: Skin Appendage Disorders
https://www.readbyqxmd.com/read/29764961/genome-wide-search-for-quantitative-trait-loci-controlling-important-plant-and-flower-traits-in-petunia-using-an-interspecific-recombinant-inbred-population-of-petunia-axillaris-and-petunia-exserta
#16
Zhe Cao, Yufang Guo, Qian Yang, Yanhong He, Mohammed Fetouh, Ryan M Warner, Zhanao Deng
A major bottleneck in plant breeding has been the much limited genetic base and much reduced genetic diversity in domesticated, cultivated germplasm. Identification and utilization of favorable gene loci or alleles from wild or progenitor species can serve as an effective approach to increasing genetic diversity and breaking this bottleneck in plant breeding. This study was conducted to identify quantitative trait loci (QTL) in wild or progenitor petunia species that can be used to improve important horticultural traits in garden petunia...
May 15, 2018: G3: Genes—Genomes—Genetics
https://www.readbyqxmd.com/read/29761018/behavioral-and-neurophysiological-abnormalities-during-cued-continuous-performance-tasks-in-patients-with-mild-traumatic-brain-injury
#17
Weixiang Zhao, Ruhong Wu, Suhong Wang, Haihui Qi, Yitao Qian, Suinuan Wang
Objective: This study's aim was to investigate the features and neural mechanisms of sustained attention in patients with mild traumatic brain injury (mTBI) by comparing and analyzing neuropsychological, behavioral, event-related potentials, and event-related desynchronization and synchronization between mTBI patients and healthy controls. Methods: Twenty mTBI patients with mTBI and 20 healthy controls underwent the Mini-Mental State Examination (MMSE) and a cued continuous performance task (AX-CPT)...
May 2018: Brain and Behavior
https://www.readbyqxmd.com/read/29759906/determining-glenoid-component-version-after-total-shoulder-arthroplasty
#18
Manish P Mehta, Laura A Vogel, Brian B Shiu, Elizabeth R Dennis, Djuro Petkovic, William N Levine, Charles M Jobin
BACKGROUND: Glenoid component loosening after total shoulder arthroplasty (TSA) may occur if retroversion is not corrected to <10°. However, accurately measuring postoperative glenoid component version has been difficult without postoperative computed tomography (CT), adding cost and radiation exposure outside of the standard radiographic follow-up. We present a new method to assess glenoid component version after TSA using only routine preoperative CT and postoperative radiographs (x-rays)...
May 11, 2018: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/29759788/novel-extravascular-defibrillation-configuration-with-a-coil-in-the-substernal-space-the-asd-clinical-study
#19
Joseph Y S Chan, Jacek Lelakowski, Francis D Murgatroyd, Lucas V Boersma, Jian Cao, Vladimir Nikolski, Griet Wouters, Mark C S Hall
OBJECTIVES: This study assessed the defibrillation efficacy of the substernal-lateral electrode configuration. BACKGROUND: Subcutaneous implantable cardioverter-defibrillators (ICDs) are regarded as alternatives to transvenous ICDs in certain subjects. However, substantially higher shock energy of up to 80 J may be required. Proposed is a new defibrillation method of placing the shock coil into the substernal space. METHODS: This prospective, nonrandomized, feasibility study was conducted in subjects scheduled for midline sternotomy or implant of ICD...
August 2017: JACC. Clinical Electrophysiology
https://www.readbyqxmd.com/read/29759645/complementary-enantioselectivity-profiles-of-chiral-cinchonan-carbamate-selectors-with-distinct-carbamate-residues-and-their-implementation-in-enantioselective-two-dimensional-high-performance-liquid-chromatography-of-amino-acids
#20
Ulrich Woiwode, Martina Ferri, Norbert M Maier, Wolfgang Lindner, Michael Lämmerhofer
A cardinal requirement for effective 2D-HPLC separations is sufficient complementarity in the retention profiles of first and second dimension separations. It is shown that retention and enantioselectivity of chiral selectors derived from cinchona alkaloids can be conveniently modulated by structural variation of the carbamate residue of the quinine/quinidine carbamate ligand of such chiral stationary phases (CSP). A variety of aliphatic and aromatic residues have been tested in comparison to non-carbamoylated quinine CSP...
April 27, 2018: Journal of Chromatography. A
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