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hypertension pulmonary

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https://www.readbyqxmd.com/read/29166717/-left-atrial-appendage-volume-is-a-valuable-predictor-of-atrial-fibrillation-recurrence-after-radiofrequency-catheter-ablation
#1
G A Zheng, C Y Lin, L Weng, J D Chen
Objective: To investigate the association between the left atrial appendage (LAA) volume and atrial fibrillation (AF) recurrence after radiofrequency catheter ablation. Methods: We prospectively enrolled sixty-two patients with AF (40 cases with paroxysmal AF, 22 cases with persistent AF) who successfully underwent a first AF catheter ablation and had performed contrast-enhanced cardiac computed tomography (CT) prior to the procedure to measure LAA volumes in our hospital from January 2012 to August 2015. Circumferential pulmonary vein isolation was performed under the guidance of three-dimension mapping system (CARTO system)...
November 24, 2017: Zhonghua Xin Xue Guan Bing za Zhi
https://www.readbyqxmd.com/read/29165173/health-and-well-being-benefits-of-spending-time-in-forests-systematic-review
#2
Byeongsang Oh, Kyung Ju Lee, Chris Zaslawski, Albert Yeung, David Rosenthal, Linda Larkey, Michael Back
BACKGROUND: Numerous studies have reported that spending time in nature is associated with the improvement of various health outcomes and well-being. This review evaluated the physical and psychological benefits of a specific type of exposure to nature, forest therapy. METHOD: A literature search was carried out using MEDLINE, PubMed, ScienceDirect, EMBASE, and ProQuest databases and manual searches from inception up to December 2016. Key words: "Forest" or "Shinrin -Yoku" or "Forest bath" AND "Health" or "Wellbeing"...
October 18, 2017: Environmental Health and Preventive Medicine
https://www.readbyqxmd.com/read/29165119/comorbidities-according-to-airflow-limitation-severity-data-from-comprehensive-health-examination-in-japan
#3
Shota Masuda, Hisamitsu Omori, Ayumi Onoue, Xi Lu, Kenichi Kubota, Noritaka Higashi, Yasuhiro Ogata, Takahiko Katoh
OBJECTIVES: The present study aimed to investigate the relationship between airflow limitation (AL) severity and comorbidities in comprehensive health examination. METHODS: This cross-sectional study included 6661 men and 6044 women aged 40-89 who underwent a lung function test during medical checkups. AL was defined as forced expiratory volume in 1 s/forced vital capacity of < 0.7. Logistic regression analysis was used to assess the association between AL severity and the presence of comorbidities...
March 20, 2017: Environmental Health and Preventive Medicine
https://www.readbyqxmd.com/read/29164429/red-blood-cell-distribution-width-as-a-related-factor-of-pulmonary-arterial-hypertension-in-patients-with-systemic-sclerosis
#4
Jiuliang Zhao, Hongnan Mo, Xiaoxiao Guo, Qian Wang, Dong Xu, Yong Hou, Zhuang Tian, Yongtai Liu, Hui Wang, Jinzhi Lai, Mengtao Li, Xiaofeng Zeng
The aim of this study was to investigate the utility of red blood cell distribution width (RDW) as a simple and readily available marker of occurrence of pulmonary arterial hypertension (PAH) in patients with systemic sclerosis (SSc). One hundred and forty-five consecutive patients with SSc were recruited to the single-center cross-sectional study. Demographic characteristics, hematological parameters, Modified Rodnan Skin Score, and World Health Organization functional classification were determined. Diagnosis of PAH was based on screening by echocardiography and was confirmed by right heart catheterization...
November 21, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/29163841/assessing-right-ventricular-function-in-pulmonary-hypertension-patients-and-the-correlation-with-the-new-york-heart-association-nyha-classification
#5
Xiaoke Shang, Shuna Xiao, Nianguo Dong, Rong Lu, Lijun Wang, Bin Wang, Yousan Chen, Liang Zhong, Mei Liu
This investigation aimed to compare the pressure-volume loop (PV loop) measurements in three less symptomatic categories (New York Heart Association classes , NYHA I, II, and III) of pulmonary hypertension (PH) patients since NYHA classification system performance is limited by the shortcomings discussed above. Thirty-six patients were enrolled in this study with PV loop measurement acquisition via micro-conductance catheters. Functional classification according to NYHA was determined with comprehensive assessing function and activity...
October 27, 2017: Oncotarget
https://www.readbyqxmd.com/read/29163663/an-unusual-and-rare-form-of-truncus-arteriosus-in-an-asymptomatic-woman
#6
Maryam Nabati
Persistent truncus arteriosus is a rare congenital cardiac malformation. It is characterized by a single great artery arising from the heart which supplies the aorta, the origin of coronary arteries and pulmonary arteries. Without surgery, prognosis is poor and 90% of these patients die before one year of age. We report a rare case of an asymptomatic 35-year-old woman with uncorrected persistent truncus arteriosus and hypoplastic right and left pulmonary arteries. Hypoplastic branch pulmonary arteries prevented the development of severe pulmonary arterial hypertension...
November 2017: Ultrasound: Journal of the British Medical Ultrasound Society
https://www.readbyqxmd.com/read/29162557/self-management-and-clinical-decision-support-for-patients-with-complex-chronic-conditions-through-the-use-of-smartphone-based-telemonitoring-randomized-controlled-trial-protocol
#7
Emily Seto, Patrick Ware, Alexander G Logan, Joseph A Cafazzo, Kenneth R Chapman, Phillip Segal, Heather J Ross
BACKGROUND: The rising prevalence of chronic illnesses hinders the sustainability of the health care system because of the high cost of frequent hospitalizations of patients with complex chronic conditions. Clinical trials have demonstrated that telemonitoring can improve health outcomes, but they have generally been limited to single conditions such as diabetes, hypertension, or heart failure. Few studies have examined the impact of telemonitoring on complex patients with multiple chronic conditions, although these patients may benefit the most from this technology...
November 21, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/29162436/effect-of-intermedin-adrenomedullin2-on-the-pulmonary-vascular-bed-in-hypoxia-induced-pulmonary-hypertensive-rats
#8
Gokcen Telli, Banu Cahide Tel, Nilgun Yersal, Petek Korkusuz, Bulent Gumusel
AIMS: This study aimed to investigate the effect and mechanism of action of intermedin/adrenomedullin2 (IMD/AM2) on the pulmonary vascular bed in pulmonary hypertensive rats. MATERIALS AND METHODS: Male Sprague-Dawley rats were exposed to hypobaric hypoxia for 3 weeks to induce pulmonary hypertension (PHT). The development of PHT was confirmed by histopathological analyses and measurement of hematocrit, basal perfusion pressure, and right ventricle hypertrophy. Subsequently, the effect of IMD/AM2 in pulmonary hypertensive rats was assessed with both, isolated organ bath and isolated lung perfusion studies...
November 18, 2017: Life Sciences
https://www.readbyqxmd.com/read/29161579/correlation-between-lung-perfusion-blood-volume-and-spect-images-in-patients-with-chronic-thromboembolic-pulmonary-hypertension-by-balloon-pulmonary-angioplasty
#9
Hirofumi Koike, Eijun Sueyoshi, Ichiro Sakamoto, Masataka Uetani, Tomoo Nakata, Kouji Maemura
OBJECTIVES: We evaluated the reperfusion by balloon pulmonary angioplasty (BPA) in lung PBV and SPECT images. METHODS: In total, 17 patients and 57 sessions were evaluated. Pre-BPA and post-BPA lung PBV and SPECT/CT images, based on both anatomical segments and physiologic regions (upper/middle/lower) were compared. RESULTS: BPA had a positive effect on most hypoperfused/unperfused segments/regions. There was generally a high rate of agreement between PBV measurements and SPECT/CT...
November 11, 2017: Clinical Imaging
https://www.readbyqxmd.com/read/29161284/lung-and-heart-lung-transplantation-in-pulmonary-arterial-hypertension
#10
Manuel López-Meseguer, Carlos A Quezada, Maria A Ramon, María Lázaro, Laura Dos, Antonio Lara, Raquel López, Isabel Blanco, Pilar Escribano, Antonio Roman
BACKGROUND: Real use of lung (LT) and heart-lung (HLT) transplantation in pulmonary arterial hypertension (PAH) is unknown. The objectives were to describe the indication of these procedures on PAH treatment in a national cohort of PAH patients, and to analyze the potential improvement of its indication in severe patients. METHODS: Eligibility for LT/HLT was assessed for each deceased patient. Incident patients from REHAP diagnosed between January 2007 and March 2015 and considered eligible for LT/HLT were grouped as follows: those who finally underwent transplantation (LTP) and those who died (D-Non-LT)...
2017: PloS One
https://www.readbyqxmd.com/read/29161076/obesity-and-metabolic-abnormalities-in-chronic-obstructive-pulmonary-disease
#11
Emiel F M Wouters
Chronic obstructive pulmonary disease (COPD) and obesity are major causes of morbidity and mortality worldwide, and a relationship between COPD and obesity is increasingly recognized. The nature and underlying mechanisms of the link between obesity and COPD are still largely unknown. Obesity, and abdominal adiposity in particular, is linked to metabolic syndrome. Hypertension, hyperglycemia, and abdominal adiposity seem to be the most prevalent components of metabolic syndrome in COPD. Adipose tissues function as a source of a variety of signaling molecules in the pathobiology of respiratory diseases...
November 2017: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/29160639/predictors-of-mortality-in-neonates-with-giant-omphaloceles
#12
Amulya K Saxena, Maja Raicevic
INTRODUCTION: This analysis was performed a review of giant-omphaloceles to determine the predictors of mortality. EVIDENCE ACQUISITION: Pubmed® and KoBson databases were searched for terms "giant" "omphalocele" and "mortality". Primary end points included mortality correlation with gestational age (GA), birth weight (BW), eviscerated organs, associated anomalies and management. To calculate mean and median values IBM SPSS version 23.0 was used. EVIDENCE SYNTHESIS: After de-duplication and review search revealed 42 articles of which 23 met our inclusion criteria with 396 giant-omphaloceles for this analysis...
November 21, 2017: Minerva Pediatrica
https://www.readbyqxmd.com/read/29159668/new-pulmonary-hypertension-model-in-conscious-dogs-to-investigate-pulmonary-selectivity-of-acute-pharmacological-interventions
#13
Thomas Mondritzki, Philip Boehme, Lena Schramm, Julia Vogel, Ilka Mathar, Peter Ellinghaus, Peter Kolkhof, Erwin Bischoff, Jörg Hüser, Wilfried Dinh, Peter Sandner, Hubert Truebel
PURPOSE: Testing of investigational drugs in animal models is a critical step in drug development. Current models of pulmonary hypertension (PH) have limitations. The most relevant outcome parameters such as pulmonary artery pressure (PAP) are measured invasively which requires anesthesia of the animal. We developed a new canine PH model in which pulmonary vasodilators can be characterized in conscious dogs and lung selectivity can be assessed non-invasively. METHODS: Telemetry devices were implanted to measure relevant hemodynamic parameters in conscious dogs...
November 20, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/29159269/pulmonary-artery-dysfunction-in-chronic-thromboembolic-pulmonary-hypertension
#14
Hidetoshi Chibana, Nobuhiro Tahara, Naoki Itaya, Takashi Ishimatsu, Masahiro Sasaki, Motoki Sasaki, Takaharu Nakayoshi, Masanori Ohtsuka, Shinji Yokoyama, Ken-Ichiro Sasaki, Takafumi Ueno, Yoshihiro Fukumoto
Background: Unresolved thromboemboli in the pulmonary arteries (PA) is known to cause chronic thromboembolic pulmonary hypertension (CTEPH). However, it remains unknown if vascular dysfunction in pulmonary arteries exists in patients with CTEPH. Methods and results: We enrolled 7 female patients with CTEPH in this study, who have stable pulmonary hemodynamics after balloon pulmonary angioplasty (age; 73.6 ± 3.0 years old, mean right atrial pressure; 4.1 ± 0...
December 2017: IJC Heart & Vasculature
https://www.readbyqxmd.com/read/29158679/treatment-of-pulmonary-hypertension-with-left-heart-disease-a-concise-review
#15
REVIEW
Anish Desai, Shilpa A Desouza
Pulmonary hypertension (PH) is defined by a mean pulmonary artery pressure ≥ 25 mmHg, as determined by right heart catheterization. Pulmonary arterial hypertension (PAH) can no longer be considered an orphan disease given the increase in awareness and availability of new drugs. PH carries with it a dismal prognosis and leads to significant morbidity and mortality. Symptoms can range from dyspnea, fatigue and chest pain to right ventricular failure and death. PH is divided into five groups by the World Health Organization (WHO), based on etiology...
2017: Vascular Health and Risk Management
https://www.readbyqxmd.com/read/29158355/models-and-molecular-mechanisms-of-world-health-organization-group-2-to-4-pulmonary-hypertension
#16
REVIEW
Ping Yu Xiong, Francois Potus, Winnie Chan, Stephen L Archer
No abstract text is available yet for this article.
November 20, 2017: Hypertension
https://www.readbyqxmd.com/read/29157525/transcatheter-tricuspid-valve-replacement
#17
REVIEW
Amar Krishnaswamy, Jose Navia, Samir R Kapadia
Tricuspid regurgitation (TR) is a common entity, most commonly functional in nature due to right-sided dysfunction in the setting of concomitant cardiac disease or pulmonary hypertension. Patients living with TR often experience numerous limitations as a result of right-sided heart failure symptoms, including functional decline, frequent hospitalizations, liver failure, and kidney failure. Furthermore, patients with significant TR demonstrate worse survival, although a cause-and-effect relationship has not been proven...
January 2018: Interventional cardiology clinics
https://www.readbyqxmd.com/read/29157517/balloon-pulmonary-angioplasty-for-chronic-thromboembolic-pulmonary-hypertension
#18
REVIEW
Ehtisham Mahmud, Omid Behnamfar, Lawrence Ang, Mitul P Patel, David Poch, Nick H Kim
Chronic thromboembolic pulmonary hypertension (CTEPH) is associated with several risk factors but is most frequently seen as a rare consequence of an acute pulmonary embolism. Surgical pulmonary thromboendarterectomy (PTE) is potentially curative for CTEPH with the best outcomes seen for the treatment of primarily proximal, accessible lobar or segmental disease. For surgically inoperable patients, percutaneous balloon pulmonary angioplasty (BPA) is feasible and has good short- to mid-term efficacy outcomes...
January 2018: Interventional cardiology clinics
https://www.readbyqxmd.com/read/29155375/armi-tackles-regenerative-medicine-a-new-initiative-is-bringing-industrial-scale-engineering-approaches-to-the-biomedical-world
#19
David L Chandler
Pulmonary arterial hypertension is a rare and potentially life-threatening disorder. But when prominent entrepreneur Martine Rothblatt (Figure 1), founder of Sirius radio, learned in the 1990s that her daughter had been diagnosed with this little-known condition and given only three months to live, she refused to accept that grim prognosis. Instead, Rothblatt transformed her life.
November 2017: IEEE Pulse
https://www.readbyqxmd.com/read/29154434/right-ventricular-involvement-in-cardiac-sarcoidosis-demonstrated-with-cardiac-magnetic-resonance
#20
Jan-Peter Smedema, Robert-Jan van Geuns, Gillian Ainslie, Joris Ector, Hein Heidbuchel, Harry J G M Crijns
AIMS: Cardiac involvement in sarcoidosis is reported in up to 30% of patients. Left ventricular involvement demonstrated by contrast-enhanced cardiac magnetic resonance has been well validated. We sought to determine the prevalence and distribution of right ventricular late gadolinium enhancement in patients diagnosed with pulmonary sarcoidosis. METHODS AND RESULTS: We prospectively evaluated 87 patients diagnosed with pulmonary sarcoidosis with contrast-enhanced cardiac magnetic resonance for right ventricular involvement...
November 2017: ESC Heart Failure
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