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https://www.readbyqxmd.com/read/28696012/inhibition-of-snk-spar-signaling-pathway-promotes-the-restoration-of-motor-function-in-a-rat-model-of-ischemic-stroke
#1
Qing-Yu Fan, Jing-Jie Liu, Gui-Lian Zhang, Hai-Qin Wu, Ru Zhang, Shu-Qin Zhan, Na Liu
This study aimed to investigate the effects of SPAR signaling pathway on the restoration of motor function in ischemic stroke (IS). Sprague-Dawley male rats were separated into the control and sham groups, as well as the group for middle cerebral artery occlusion (MCAO) model establishment. Successfully established rat ischemic models were randomly divided into model, SNK(MCAO-del) and pcDNA3.1-SNK groups. The evaluation of motor function among the rats in each group was assessed using a balance beam, a screen test and the Garcia scoring method...
July 11, 2017: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/28687056/the-efficacy-of-treadmill-training-on-balance-dysfunction-in-individuals-with-chronic-stroke-a-systematic-review
#2
Zachary Tally, Laura Boetefuer, Courtney Kauk, Gabriela Perez, Lorraine Schrand, Jeffrey Hoder
BACKGROUND: Physical activity and exercise interventions are useful in facilitating the functional recovery of those with chronic stroke and, routinely, are gait-specific. While treadmill training has proven useful in gait performance recovery post-stroke, its efficacy on balance dysfunction has not been  systematically reviewed. OBJECTIVES: The purpose of this systematic review was to determine the effect of treadmill training (TT) interventions on balance dysfunction in individuals with chronic stroke...
July 7, 2017: Topics in Stroke Rehabilitation
https://www.readbyqxmd.com/read/28647551/factors-predicting-falls-and-mobility-outcomes-in-patients-with-stroke-returning-home-after-rehabilitation-who-are-at-risk-of-falling
#3
Mandy Man-Di Ng, Keith D Hill, Frances Batchelor, Elissa Burton
OBJECTIVE: To identify factors predicting falls and limited mobility in people with stroke at 12 months after returning home from rehabilitation. DESIGN: Observational cohort study with 12 month follow-up. SETTING: Community. PARTICIPANTS: People with stroke (n=144) and increased falls risk discharged home from rehabilitation. INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: Falls were measured using monthly calendars completed by participants, and mobility was assessed using gait speed over five metres (high mobility (>0...
June 21, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28640006/poor-gait-performance-is-influenced-with-decreased-vestibulo-ocular-reflex-in-poststroke-patients
#4
Tsubasa Mitsutake, Maiko Sakamoto, Kozo Ueta, Shinichiro Oka, Etsuo Horikawa
The vestibulo-ocular reflex (VOR) exerts a significant influence on gait performance. Therefore, a decrease in VOR function could worsen gait impairments in patients with poststroke hemiparesis. The effects of decreased VOR function on gait performance could be further exacerbated by aging-related physical weakness and impaired motor function of the hemiparetic lower limb. The aim of our study was to evaluate the possible synergistic effect of aging and impairment in lower extremity function and the VOR on walking ability of poststroke hemiplegic patients...
August 16, 2017: Neuroreport
https://www.readbyqxmd.com/read/28638365/motor-impairments-in-transient-ischemic-attack-increase-the-odds-of-a-subsequent-stroke-a-meta-analysis
#5
Neha Lodha, Jane Harrell, Stephan Eisenschenk, Evangelos A Christou
BACKGROUND AND PURPOSE: Transient ischemic attack (TIA) increases the risk for a subsequent stroke. Typical symptoms include motor weakness, gait disturbance, and loss of coordination. The association between the presence of motor impairments during a TIA and the chances of a subsequent stroke has not been examined. In the current meta-analysis, we examine whether the odds of a stroke are greater in TIA individuals who experience motor impairments as compared with those who do not experience motor impairments...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28632106/speed-interactive-treadmill-training-using-smartphone-based-motion-tracking-technology-improves-gait-in-stroke-patients
#6
Junyoung Lee, Kyeongjin Lee, Changho Song
This study was conducted to investigate the effects of speed-interactive treadmill training (SITT) using smartphone-based motion tracking technology on gait in stroke patients. Thirty-four chronic stroke patients were randomly divided into a SITT group (n = 18) and a standard treadmill training (control) group (n = 16). The SITT group underwent smartphone-based SSIT while the control group underwent standard treadmill training. Both groups performed the training for 35 min per session, 3 times per week, for 6 weeks...
March 2, 2017: Journal of Motor Behavior
https://www.readbyqxmd.com/read/28628523/effectiveness-of-surgery-for-adults-with-hallux-valgus-deformity-a-systematic-review
#7
Jitka Klugarova, Victoria Hood, Fiona Bath-Hextall, Miloslav Klugar, Jana Mareckova, Zuzana Kelnarova
BACKGROUND: Hallux valgus (HV) is a common foot deformity. In severe stages of this condition, surgery is often necessary. Currently, there is no systematic review comparing the effectiveness of surgery over conservative treatment. OBJECTIVES: The objective of this review was to establish the effectiveness of surgery compared to conservatory management for adults with HV. INCLUSION CRITERIA TYPES OF PARTICIPANTS: The current review included adults (18 years or over) with HV deformity, excluding adults with neurological problems causing foot deformities, for example, cerebral palsy, neuropathy, stroke and multiple sclerosis...
June 2017: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/28626335/2-dimensional-analysis-of-low-limb-taping-methods-on-ambulation-for-stroke-patients
#8
Jung-Ho Lee
[Purpose] The purpose of this study was to investigate the effect of treatment on the type of taping applied before proprioceptive neuromuscular facilitation treatment. [Subjects and Methods] This study was conducted on thirty patients diagnosed with stroke. The study subjects were divided into three groups: experimental group 1, experimental group 2, and control group 3. Experimental group 1 applied Kinesio taping to the lower limb before applying proprioceptive neuromuscular facilitation technique. Experimental group 2 applied McConnell taping to the lower limb before applying proprioceptive neuromuscular facilitation technique and control group applied only proprioceptive neuromuscular facilitation technique...
June 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28619985/long-term-improvements-after-multimodal-rehabilitation-in-late-phase-after-stroke-a-randomized-controlled-trial
#9
RANDOMIZED CONTROLLED TRIAL
Lina Bunketorp-Käll, Åsa Lundgren-Nilsson, Hans Samuelsson, Tulen Pekny, Karin Blomvé, Marcela Pekna, Milos Pekny, Christian Blomstrand, Michael Nilsson
BACKGROUND AND PURPOSE: Treatments that improve function in late phase after stroke are urgently needed. We assessed whether multimodal interventions based on rhythm-and-music therapy or horse-riding therapy could lead to increased perceived recovery and functional improvement in a mixed population of individuals in late phase after stroke. METHODS: Participants were assigned to rhythm-and-music therapy, horse-riding therapy, or control using concealed randomization, stratified with respect to sex and stroke laterality...
July 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28603363/intra-rater-and-inter-rater-reliability-of-the-portable-gait-rhythmogram-in-post-stroke-patients
#10
Ryuji Miyata, Shuji Matsumoto, Seiji Miura, Kentaro Kawamura, Tomohiro Uema, Kodai Miyara, Ayana Niibo, Tadashi Ogura, Megumi Shimodozono
[Purpose] Gait analysis, such as portable gait rhythmogram (PGR) provides objective information that helps in the quantitative evaluation of human locomotion. The purpose of this study was to assess the reliability of PGR in post-stroke patients. [Subjects and Methods] Two raters (A and B) examined 44 post-stroke patients. To assess intra-rater reliability, rater A tested subjects on three separate occasions (Days 1, 2, and 3). To assess inter-rater reliability, raters A and B independently tested participants on the same occasion (Day 3)...
May 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28602121/frailty-and-risk-of-cardiovascular-diseases-in-older-persons-the-age-gene-environment-susceptibility-reykjavik-study
#11
Nicola Veronese, Kristin Sigeirsdottir, Gudny Eiriksdottir, Elisa Marques, Didier Chalhoub, Caroline Phillips, Lenore Launer, Stefania Maggi, Vilmundur Gudnason, Tamara B Harris
Frailty is a risk factor for cardiovascular diseases (CVD), but the studies available have not considered the presence of sub-clinical atherosclerotic disease as potential confounders. We investigated the association between frailty and the onset of CVD independently of sub-clinical atherosclerotic disease. For this reason, a sample of 3818 older participants participating in the Age, Gene/Environment SusceptibilityReykjavik Study (AGESReykjavik) without CVD at baseline was followed for a median of 8...
June 10, 2017: Rejuvenation Research
https://www.readbyqxmd.com/read/28582260/a-personalized-self-management-rehabilitation-system-for-stroke-survivors-a-quantitative-gait-analysis-using-a-smart-insole
#12
Richard John Davies, Jack Parker, Paul McCullagh, Huiru Zheng, Chris Nugent, Norman David Black, Susan Mawson
BACKGROUND: In the United Kingdom, stroke is the single largest cause of adult disability and results in a cost to the economy of £8.9 billion per annum. Service needs are currently not being met; therefore, initiatives that focus on patient-centered care that promote long-term self-management for chronic conditions should be at the forefront of service redesign. The use of innovative technologies and the ability to apply these effectively to promote behavior change are paramount in meeting the current challenges...
November 8, 2016: JMIR Rehabil Assist Technol
https://www.readbyqxmd.com/read/28578679/effectiveness-of-additional-trunk-exercises-on-gait-performance-study-protocol-for-a-randomized-controlled-trial
#13
Tamaya Van Criekinge, Wim Saeys, Ann Hallemans, Luc Vereeck, Willem De Hertogh, Patricia Van de Walle, Nathalie Vaes, Christophe Lafosse, Steven Truijen
BACKGROUND: Evidence is lacking concerning the effect of additional trunk rehabilitation on gait performance. Investigating gait performance by both clinical and biomechanical outcome measures might lead to new scientific insights into the importance of the trunk during gait rehabilitation in people suffering from stroke. This protocol was written according to the SPIRIT 2013 Statement. METHODS AND DESIGN: An assessor-blinded randomized controlled trial will be conducted in patients with impaired trunk control after stroke...
June 2, 2017: Trials
https://www.readbyqxmd.com/read/28574860/crouch-gait-can-be-an-effective-form-of-forced-use-no-constraint-exercise-for-the-paretic-lower-limb-in-stroke
#14
Luigi Tesio, Viviana Rota, Chiara Malloggi, Luigia Brugliera, Luigi Catino
In hemiplegic gait the paretic lower limb provides less muscle power and shows a briefer stance compared with the unaffected limb. Yet, a longer stance and a higher power can be obtained from the paretic lower limb if gait speed is increased. This supports the existence of a 'learned non-use' phenomenon, similar to that underlying some asymmetric impairments of the motion of the eyes and of the upper limbs. Crouch gait (CG) (bent-hip bent-knee, about 30° minimum knee flexion) might be an effective form of 'forced-use' treatment of the paretic lower limb...
June 1, 2017: International Journal of Rehabilitation Research. Revue Internationale de Recherches de Réadaptation
https://www.readbyqxmd.com/read/28552496/effects-of-novel-guidance-tubing-gait-on-emg-neuromuscular-imbalance-and-joint-angular-kinematics-during-locomotion-in-hemiparetic-stroke-patients
#15
Jeong J Lee, Joshua Sung H You
OBJECTIVE: To compare the immediate effects of conventional treadmill gait (CTG) and guidance tubing gait (GTG) on electromyographic (EMG) neuromuscular imbalance and knee joint kinematics in hemiparetic gait. DESIGN: Case control study. SETTING: University medical center. PARTICIPANTS: Eighteen patients with hemiparetic stroke (18 experimental, mean (SD) age 39.2 (16.8) years) and 15 healthy controls, mean age 26.3 (2...
May 25, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28549648/characterization-of-long-term-gait-deficits-in-mouse-dmcao-using-the-catwalk-system
#16
E Caballero-Garrido, J C Pena-Philippides, Z Galochkina, E Erhardt, T Roitbak
Evaluation of functional outcome is widely used across species to assess the recovery process following various pathological conditions, including spinal cord injury, musculo-skeletal injury, mithochondrial disease, neuropathic cancer, Huntington's disease, chronic pain, cortical lesion, and olivocerebellar degeneration among others. The Stroke Therapy Academic Industry Roundtable (STAIR) recommends multiple endpoints for behavioral studies in pre-clinical stroke research, to demonstrate their clinical relevance...
July 28, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28505988/intensive-seated-robotic-training-of-the-ankle-in-patients-with-chronic-stroke-differentially-improves-gait
#17
Johanna L Chang, Regina Y Lin, Maira Saul, Philip J Koch, Hermano Igo Krebs, Bruce T Volpe
BACKGROUND: Robotic driven treatment plans targeting isolated joints of the upper limb have improved the sensorimotor condition of patients with stroke. Similar intensive efforts to allay lower limb gait impairment have not been so successful. In patients with stroke, targeted robot assisted training of the ankle joint, in a seated position, has demonstrated significant alterations in ankle stiffness and foot-ankle orientation at foot strike which may provide a new treatment option for gait impairment...
May 10, 2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/28503532/changes-in-gait-kinematics-and-muscle-activity-in-stroke-patients-wearing-various-arm-slings
#18
Young-In Hwang, Jangwhon Yoon
Stroke patients often use various arm slings, but the effects of different slings on the joint kinematics and muscle activity of the arm in the gait have not been investigated. The effects of joint kinematics and muscle activity in the gait were investigated to provide suggestions for gait training for stroke patients. In all, 10 chronic stroke patients were voluntarily recruited. An eight-camera three-dimensional motion analysis system was used to measure joint kinematics while walking; simultaneously, electromyography data were collected for the anterior and posterior deltoids and latissimus dorsi...
April 2017: Journal of Exercise Rehabilitation
https://www.readbyqxmd.com/read/28491477/the-effect-of-diabetic-peripheral-neuropathy-on-ground-reaction-forces-during-straight-walking-in-stroke-survivors
#19
Amirah Mustapa, Maria Justine, Nadia Mohd Mustafah, Haidzir Manaf
Purpose. The aim of this present study was to investigate the ground reaction forces (GRFs) alterations in stroke survivors with diabetic peripheral neuropathy (DPN). Methods. Ten stroke survivors with DPN, 10 stroke survivors without DPN, and 10 healthy controls with matched body weight between groups participated in this case-control cross-sectional study. Three-dimensional GRFs (anterior-posterior, medial-lateral, and vertical) were collected at a comfortable walking speed using the Nexus Vicon motion analysis system and force plate...
2017: Rehabilitation Research and Practice
https://www.readbyqxmd.com/read/28488268/electromechanical-assisted-training-for-walking-after-stroke
#20
REVIEW
Jan Mehrholz, Simone Thomas, Cordula Werner, Joachim Kugler, Marcus Pohl, Bernhard Elsner
BACKGROUND: Electromechanical- and robotic-assisted gait-training devices are used in rehabilitation and might help to improve walking after stroke. This is an update of a Cochrane Review first published in 2007. OBJECTIVES: To investigate the effects of automated electromechanical- and robotic-assisted gait-training devices for improving walking after stroke. SEARCH METHODS: We searched the Cochrane Stroke Group Trials Register (last searched 9 August 2016), the Cochrane Central Register of Controlled Trials (CENTRAL) (the Cochrane Library 2016, Issue 8), MEDLINE in Ovid (1950 to 15 August 2016), Embase (1980 to 15 August 2016), CINAHL (1982 to 15 August 2016), AMED (1985 to 15 August 2016), Web of Science (1899 to 16 August 2016), SPORTDiscus (1949 to 15 September 2012), the Physiotherapy Evidence Database (PEDro) (searched 16 August 2016), and the engineering databases COMPENDEX (1972 to 16 November 2012) and Inspec (1969 to 26 August 2016)...
May 10, 2017: Cochrane Database of Systematic Reviews
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