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https://www.readbyqxmd.com/read/28211272/effects-of-dimethyloxalylglycine-embedded-poly-%C3%AE%C2%B5-caprolactone-fiber-meshes-on-wound-healing-in-diabetic-rats
#1
Qiankun Zhang, Joung-Hwan Oh, Chan Ho Park, Jeong-Hwa Baek, Hyun-Mo Ryoo, Kyung Mi Woo
Impaired wound healing in diabetic patients is associated with altered inflammatory responses, poor angiogenesis, deficient extracellular matrix (ECM) component, and peripheral neuropathy. To develop a wound dressing that is capable of the controlled delivery of bioactive small molecules that can improve diabetic wound healing, dimethyloxalylglycine (DMOG)-embedded poly(ε-caprolactone) (PCL) fiber (PCLF/DMOG) meshes are fabricated by electrospinning, and the effects of the PCLF/DMOG meshes on wound healing in diabetic rats are evaluated...
February 17, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28209035/electrospun-perovskite-nanofibers
#2
Dongsheng Chen, Yanyan Zhu
CH3NH3PbI3 perovskite nanofibers were synthesized by versatile electrospinning techniques. The synthetic CH3NH3PbI3 nanofibers were characterized by X-ray diffraction, scanning electron microscopy, thermogravimetric analysis, and photoluminescence. As counter electrodes, the synthesized nanofibers increased the performance of the dye-sensitized solar cells from 1.58 to 2.09%. This improvement was attributed to the enhanced smoothness and efficiency of the electron transport path. Thus, CH3NH3PbI3 perovskites nanofibers are potential alternative to platinum counter electrodes in dye-sensitized solar cells...
December 2017: Nanoscale Research Letters
https://www.readbyqxmd.com/read/28209034/production-of-conductive-pedot-coated-pva-go-composite-nanofibers
#3
Nur Afifah Zubair, Norizah Abdul Rahman, Hong Ngee Lim, Yusran Sulaiman
Electrically conductive nanofiber is well known as an excellent nanostructured material for its outstanding performances. In this work, poly(3,4-ethylenedioxythiophene) (PEDOT)-coated polyvinyl alcohol-graphene oxide (PVA-GO)-conducting nanofibers were fabricated via a combined method using electrospinning and electropolymerization techniques. During electrospinning, the concentration of PVA-GO solution and the applied voltage were deliberately altered in order to determine the optimized electrospinning conditions...
December 2017: Nanoscale Research Letters
https://www.readbyqxmd.com/read/28209029/synthesis-and-electrochemical-property-of-limn2o4-porous-hollow-nanofiber-as-cathode-for-lithium-ion-batteries
#4
Lianfeng Duan, Xueyu Zhang, Kaiqiang Yue, Yue Wu, Jian Zhuang, Wei Lü
The LiMn2O4 hollow nanofibers with a porous structure have been synthesized by modified electrospinning techniques and subsequent thermal treatment. The precursors were electrospun directly onto the fluorine-doped tin oxide (FTO) glass. The heating rate and FTO as substrate play key roles on preparing porous hollow nanofiber. As cathode materials for lithium-ion batteries (LIBs), LiMn2O4 hollow nanofibers showed the high specific capacity of 125.9 mAh/g at 0.1 C and a stable cycling performance, 105.2 mAh/g after 400 cycles...
December 2017: Nanoscale Research Letters
https://www.readbyqxmd.com/read/28208112/systematic-mechanical-evaluation-of-electrospun-gelatin-meshes
#5
Annabel L Butcher, Ching Theng Koh, Michelle L Oyen
Electrospinning is a simple and efficient process for producing sub-micron fibres. However, the process has many variables, and their effects on the non-woven mesh of fibres is complex. In particular, the effects on the mechanical properties of the fibre meshes are poorly understood. This paper conducts a parametric study, where the concentration and bloom strength of the gelatin solutions are varied, while all electrospinning process parameters are held constant. The effects on the fibrous meshes are monitored using scanning electron microscopy and mechanical testing under uniaxial tension...
February 7, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28205050/composite-electrospun-scaffold-derived-from-recombinant-fibroin-of-weaver-ant-oecophylla-smaragdina-as-cell-substratum
#6
Arunrat Khamhaengpol, Sineenat Siri
Unlike silkworm (Bombyx mori) fibroin (SF), weaver ant (Oecophylla smaragdina) fibroin (WAF) is much less studied. Due to differences in amino acid composition and protein structure, this work aimed to produce the recombinant WAF protein, designated as WAF1, and investigated on its potential application as a biomaterial for producing a cell-substratum. The composite electrospun scaffolds derived from poly(vinyl alcohol) (PVA), WAF1, and extracted SF were produced by electrospinning. SEM images revealed non-woven and smooth fibers of PVA, PVA-WAF1, and PVA-SF scaffolds with the average diameters of 204...
February 15, 2017: Applied Biochemistry and Biotechnology
https://www.readbyqxmd.com/read/28199222/liquid-crystals-in-micron-scale-droplets-shells-and-fibers
#7
Martin Urbanski, Catherine G Reyes, JungHyun Noh, Anshul Sharma, Yong Geng, Venkata Subba Rao Jampani, Jan P F Lagerwall
The extraordinary responsiveness and large diversity of self-assembled structures of liquid crystals are well documented and they have been extensively used in devices like displays. For long, this application route strongly influenced academic research, which frequently focused on the performance of liquid crystals in display-like geometries, typically between flat, rigid substrates of glass or similar solids. Today a new trend is clearly visible, where liquid crystals confined within curved, often soft and flexible, interfaces are in focus...
February 15, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/28196320/flexible-and-highly-biocompatible-nanofiber-based-electrodes-for-neural-surface-interfacing
#8
Dong Nyoung Heo, Han-Jun Kim, Yijae Lee, Min Heo, Sang Jin Lee, Donghyun Lee, Sun Hee Do, Soo Hyun Lee, Il Keun Kwon
Polyimide (PI)-based electrodes have been widely used as flexible biosensors in implantable device applications for recording biological signals. However, the long-term quality of neural signals obtained from PI-based nerve electrodes tends to decrease due to nerve damage by neural tissue compression, mechanical mismatch and insufficient fluid exchange between the neural tissue and electrodes. Here, we resolve these problems with a developed PI nanofiber (NF)-based nerve electrode for stable neural signal recording, which can be fabricated via electrospinning and inkjet printing...
February 14, 2017: ACS Nano
https://www.readbyqxmd.com/read/28195483/development-of-oromucosal-dosage-forms-by-combining-electrospinning-and-inkjet-printing
#9
Mirja Palo, Karin Kogermann, Ivo Laidmäe, Andres Meos, Maren Preis, Jyrki Heinämäki, Niklas Sandler
Printing technology has been shown to enable flexible fabrication of solid dosage forms for personalized drug therapy. Several methods can be applied for tailoring the properties of the printed pharmaceuticals. In this study, the use of electrospun fibrous substrates in the fabrication of inkjet-printed dosage forms was investigated. A single-drug formulation with lidocaine hydrochloride (LH) and a combination drug system containing LH and piroxicam (PRX) for oromucosal administration were prepared. The LH was deposited on the electrospun and cross-linked gelatin substrates by inkjet printing, whereas PRX was incorporated within the substrate fibers during electrospinning...
February 14, 2017: Molecular Pharmaceutics
https://www.readbyqxmd.com/read/28193044/engineered-iro2-nio-core-shell-nanowires-for-sensitive-non-enzymatic-detection-of-trace-glucose-in-saliva
#10
Junjun Wang, Lin Xu, Yang Lu, Kuang Sheng, Wei Liu, Cong Chen, Yang Li, Biao Dong, Hongwei Song
Hierarchical core-shell IrO2@NiO nanowires (NWs) have been designed through two simple steps, which combined electrospinning of IrO2 conductive core and chemical bath deposition growth of ultracontinuous NiO nanoflakes. Scanning electron microscopy, transmission electron microscopy, X-ray diffraction, energy-dispersive X-ray spectrometry mapping, and X-ray photoelectron spectroscopy were employed to characterize the morphologies and structures of the as-prepared samples, and the results were also carefully compared with that of pure NiO nanoflowers and IrO2 NWs...
December 20, 2016: Analytical Chemistry
https://www.readbyqxmd.com/read/28192154/electrospun-polyurethane-nanofiber-scaffolds-with-ciprofloxacin-oligomer-effect-on-drug-release-and-cell-attachment-versus-free-drug
#11
Meghan Ee Wright, Ian C Parrag, Meilin Yang, J Paul Santerre
An electrospun degradable polycarbonate urethane (PCNU) nanofiber scaffold loaded with antibiotic was investigated in terms of antibacterial efficacy and cell compatibility for potential use in gingival tissue engineering. Antimicrobial oligomer (AO), a compound which consists of two molecules of ciprofloxacin (CF) covalently bound via hydrolysable linkages to triethylene glycol (TEG), was incorporated via a one-step blend electrospinning process using a single solvent system at 7 and 15% w/w equivalent CF with respect to the PCNU...
February 10, 2017: Journal of Controlled Release: Official Journal of the Controlled Release Society
https://www.readbyqxmd.com/read/28191722/gold-nanoparticles-immobilized-on-electrospun-titanium-dioxide-nanofibers-for-catalytic-reduction-of-4-nitrophenol
#12
Halit Cavusoglu, Burak Zafer Buyukbekar, Huseyin Sakalak, Sebastian Kohsakowski
This study involves the preparation and catalytic properties of anatase titanium dioxide nanofibers (TiO2 NFs) supported gold nanoparticles (Au NPs) using a model reaction based on the reduction of 4-nitrophenol (NP) into 4-aminophenol (AP) by sodium borohydride (NaBH4). The fabrication of surfactant-free Au NPs was performed using pulsed laser ablation in liquid (PLAL) technique. The TiO2 NFs were fabricated by a combination of electrospinning and calcination process using a solution containing poly(vinyl pyrolidone)(PVP) and titanium isopropoxide...
February 13, 2017: Chemphyschem: a European Journal of Chemical Physics and Physical Chemistry
https://www.readbyqxmd.com/read/28185991/formulation-and-characterization-of-nanofibers-and-films-with-carvedilol-prepared-by-electrospinning-and-solution-casting-method
#13
Marko Krstić, Marija Radojević, Dušica Stojanović, Vesna Radojević, Petar Uskoković, Svetlana Ibrić
The preparation and characterization of films and nanofibers with carvedilol as a poorly water-soluble drug in poly (ethylene oxide) (PEO) polymer were investigated. Films are prepared by solution casting method, and nanofibers by electrospinning from a polymer solution. Water and mixture of ethanol and water were used as solvents. FT-IR analysis of the samples showed that there was no interaction between the polymer and the drug substance. DSC analysis revealed that carvedilol was dissolved in the polymer and influenced the degree of crystallinity of PEO...
February 6, 2017: European Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28185940/twisting-electrospun-nanofiber-fine-strips-into-functional-sutures-for-sustained-co-delivery-of-gentamicin-and-silver
#14
Shixuan Chen, Liangpeng Ge, Aubrey Mueller, Mark A Carlson, Matthew J Teusink, Franklin D Shuler, Jingwei Xie
Surgical site infections (SSIs) represent the most common nosocomial infection among surgical patients. In order to prevent SSIs in a sustained manner and lessen side effects, we developed a twisting method for generation of nanofiber-based sutures capable of simultaneous delivery of silver and gentamicin. The prepared sutures are composed of core-sheath nanofibers with gentamicin/pluronic F127 in the core and silver/PCL in the sheath produced by co-axial electrospinning. The diameters of obtained sutures range from ~ 80 μm to ~ 1...
February 6, 2017: Nanomedicine: Nanotechnology, Biology, and Medicine
https://www.readbyqxmd.com/read/28185364/enabling-heterogeneous-gold-catalysis-with-patchy-micelles
#15
John R Finnegan, Jessica Gwyther, Ian Manners
Patch works! Patchy block copolymer micelles with a corona consisting of two chemically different patches have been designed for the selective binding of catalytically active nanoparticles. The fabrication of nonwoven supports by electrospinning was combined with crystallization-driven self-assembly for precise control over micelle formation to prepare a new recyclable catalyst platform.
February 10, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28185267/regulation-of-adipose-tissue-derived-stromal-cell-orientation-and-motility-in-2d-and-3d-cultures-by-direct-current-electrical-field
#16
Gang Yang, Haiyan Long, Xiaomei Ren, Kunlong Ma, Zhenghua Xiao, Ying Wang, Yingqiang Guo
Cell alignment and motility play a critical role in a variety of cell behaviors, including cytoskeleton reorganization, membrane-protein relocation, nuclear gene expression, and extracellular matrix remodeling. Direct current electric field (EF) in vitro can direct many types of cells to align vertically to EF vector. In this work, we investigated the effects of EF stimulation on rat adipose-tissue-derived stromal cells (ADSCs) in 2D-culture on plastic culture dishes and in 3D-culture on various scaffold materials, including collagen hydrogels, chitosan hydrogels and poly(L-lactic acid)/gelatin electrospinning fibers...
February 10, 2017: Development, Growth & Differentiation
https://www.readbyqxmd.com/read/28183666/fabrication-of-electrospun-hpgl-scaffolds-via-glycidyl-methacrylate-cross-linker-morphology-mechanical-and-biological-properties
#17
Fernando José Costa Baratéla, Olga Zazuco Higa, Esdras Duarte Dos Passos, Alvaro Antonio Alencar de Queiroz
Electrospinning is a suitable method to produce scaffolds composed of nanoscale to microscale fibers, which are comparable to the extracellular matrix (ECM). Hyperbranched polyglycerol (HPGL) is a highly biocompatible polyether polyol potentially useful for the design of fibrous scaffolds mimicking the ECM architecture. However, scaffolds developed from HPGL have poor mechanical properties and morphological stability in the aqueous environments required for tissue engineering applications. This work reports the production of stable electrospun HPGL scaffolds (EHPGLS) using glycidyl methacrylate (GMA) as cross-linker to enhance the water stability and mechanical property of electrospun HPGL...
April 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28183642/magnetic-nanoparticle-loaded-electrospun-polymeric-nanofibers-for-tissue-engineering
#18
Heng Zhang, JiYi Xia, XianLun Pang, Ming Zhao, BiQiong Wang, LingLin Yang, HaiSu Wan, JingBo Wu, ShaoZhi Fu
Magnetic nanoparticles have been one of the most attractive nanomaterials for various biomedical applications including magnetic resonance imaging (MRI), diagnostic contrast enhancement, magnetic cell separation, and targeted drug delivery. Three-dimensional (3-D) fibrous scaffolds have broad application prospects in the biomedical field, such as drug delivery and tissue engineering. In this work, a novel three-dimensional composite membrane composed of the tri-block copolymer poly(ε-caprolactone)-poly(ethylene glycol)-poly(ε-caprolactone) (PCL-PEG-PCL, PCEC) and magnetic iron oxide nanoparticles (Fe3O4 NPs) were fabricated using electrospinning technology...
April 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28183638/electrospinning-of-silk-fibroin-from-all-aqueous-solution-at-low-concentration
#19
Yuki Kishimoto, Hideaki Morikawa, Shigeru Yamanaka, Yasushi Tamada
Non-woven mats of Bombyx mori silk fibroin were fabricated using electrospinning with an all aqueous solution at <10wt% without any co-existing water soluble polymer such as PEO. The fibroin aqueous solution electrospinnability was affected by the fibroin molecular weight and the spinning solution pH. Hot-water treatment without any alkaline reagent or soap produced higher molecular weight fibroin than the typical degumming process did. The higher molecular weight fibroin provided good electrospinnability...
April 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28183630/polyvinyl-alcohol-composite-nanofibres-containing-conjugated-levofloxacin-chitosan-for-controlled-drug-release
#20
Javid Jalvandi, Max White, Yuan Gao, Yen Bach Truong, Rajiv Padhye, Ilias Louis Kyratzis
A range of biodegradable drug-nanofibres composite mats have been reported as drug delivery systems. However, their main disadvantage is the rapid release of the drug immediately after application. This paper reports an improved system based on the incorporation of drug conjugated-chitosan into polyvinyl alcohol (PVA) nanofibers. The results showed that controlled release of levofloxacin (LVF) could be achieved by covalently binding LVF to low molecular weight chitosan (CS) via a cleavable amide bond and then blending the conjugated CS with polyvinyl alcohol (PVA) nanofibres prior to electrospinning...
April 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
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