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Indrani Godakanda, Chrishantha Abeysena, Ayesha Lokubalasooriya
OBJECTIVE: To determine the risk of sedentary behavior during leisure time, physical activity and dietary habits on overweight among school children aged 14-15 years in Kalutara District, Sri Lanka. RESULTS: School based case-control study was conducted during September to November 2013 including 176 overweight children as cases and 704 children with normal weight as controls. Cases were defined as body mass index for age and sex of ≥ +1SD and controls as those in the range of -2SD to +1SD...
March 20, 2018: BMC Research Notes
Hee Sun Kang, Jennie C De Gagne, Ye Dong Son, Sun-Mi Chae
PROBLEM: It has been reported that some adolescents and young women who started taking human papillomavirus (HPV) vaccination are not completing all three doses. The aim of this study was to systematically review intervention studies on HPV vaccination completion. ELIGIBILITY CRITERIA: Intervention studies with a comparison group that assessed HPV vaccination completion rate as the primary outcome variable in adolescents and adults younger than 26years of age, and published in English from 2006 to 2016, were eligible for review...
March 2018: Journal of Pediatric Nursing
Vanessa Romotzky, Julia Strupp, Alexander Hayn, Jens Ulrich Rüffer, Judith Grümmer, Raymond Voltz
OBJECTIVE: We aimed to elucidate the views on life as narrated by patients in palliative care (PC) to find out what patients deem to be essential in their life, whether something has changed concerning their view of life in light of the disease, and whether interviewees would like to give others something to take with them. METHOD: Data were collected from narrative audio and video interviews with 18 inpatients in a specialized PC unit. Interviews were recorded and transcribed verbatim and analyzed using qualitative content analysis applying MAXQDA software...
March 8, 2018: Palliative & Supportive Care
Claire Townsend Ing, Robin E S Miyamoto, Rui Fang, Mapuana Antonio, Diane Paloma, Kathryn L Braun, Joseph Keawe'aimoku Kaholokula
BACKGROUND: Native Hawaiians and other Pacific Islanders have high rates of overweight and obesity compared with other ethnic groups in Hawai'i. Effective weight loss and weight loss-maintenance programs are needed to address obesity and obesity-related health inequities for this group. AIMS: Compare the effectiveness of a 9-month, worksite-based, weight loss-maintenance intervention delivered via DVD versus face-to-face in continued weight reduction and weight loss maintenance beyond the initial weight loss phase...
March 1, 2018: Health Education & Behavior: the Official Publication of the Society for Public Health Education
Eric M Maiese, Claire Ainsworth, Jean-Gabriel Le Moine, Outi Ahdesmäki, Judith Bell, Emma Hawe
PURPOSE: New therapies, including daratumumab plus lenalidomide plus dexamethasone (DRd) and daratumumab plus bortezomib plus dexamethasone (DVd), have recently been approved in the United States for patients with multiple myeloma (MM) who have received at least 1 prior line of therapy. However, few treatments have been compared in head-to-head clinical trials to determine the most efficacious therapy. In an update of the POLLUX (Phase 3 Study Comparing DRd Versus Rd in Subjects with Relapsed or Refractory Multiple Myeloma [RRMM]) trial, median progression-free survival (PFS) for DRd was not reached; the hazard ratio compared with Rd was 0...
February 27, 2018: Clinical Therapeutics
Anshu Priya, Subrata Hait
Comprehensive characterization of printed circuit board (PCB) of end-of-life electrical and electronic equipment (EEE) is obligatory for prospective profitable beneficiation. In this study, beneficiation oriented comprehensive characterization of two brands of PCBs each of 16 end-of-life EEE was conducted in terms of their physicochemical characteristics with special emphasis on the content of 16 general elements, 2 precious metals and 15 rare earth elements (REEs). General elements and their highest weight percent composition found in different PCBs of the EEEs were Cu (23% in laptop), Al (6% in computer), Pb (15% in DVD player) and Ba (7% in TV)...
February 14, 2018: Waste Management
Daqian Jiang, Wei-Qiang Chen, Xianlai Zeng, Linbin Tang
Bisphenol A (BPA), a synthetic organic chemical, is creating a new category of ecological and human health challenges due to unintended leakage. Effectively managing the use and leakage of BPA can benefit from an understanding of the anthropogenic BPA cycle (i.e., the size of BPA flows and stocks). In this work, we provide a dynamic analysis of the anthropogenic BPA cycle in China for 2000-2014. We find that China's BPA inflows haveconsumption has increased 10-fold since 2000, to approximately ~3 million tonnes/year...
February 13, 2018: Environmental Science & Technology
Chih-Yin Hsiao, Kuei-Min Chen, Han-Ya Tsai, Hsin-Ting Huang, Yin-Yin Cheng, Athena Yijung Tsai
OBJECTIVES: To test the long-term effects of the 12-month Healthy Beat Acupunch (HBA) exercise program on the self-perceived health and sleep quality of older adults in community care centers, and to compare the effects of two delivery methods: instructor-led HBA for the first 6 months and DVD-guided HBA for another 6 months. DESIGN: Cluster-randomized controlled trial. SETTING: Eight community care centers. PARTICIPANTS: In total, 232 participants were recruited from eight community care centers, and cluster-randomized to the experimental (4 centers, N = 113) and control (4 centers, N = 119) groups...
January 31, 2018: American Journal of Geriatric Psychiatry
Hebe Mattos, Martha Abreu, Isabel Castro
An analytical essay of the process of image production, audiovisual archive formation, analysis of sources, and creation of the filmic narrative of the four historiographic films that form the DVD set Passados presentes (Present pasts) from the Oral History and Image Laboratory of Universidade Federal Fluminense (Labhoi/UFF). From excerpts from the audiovisual archive of Labhoi and the films made, the article analyzes: how the problem of research (the memory of slavery, and the legacy of the slave song in the agrofluminense region) led us to the production of images in a research situation; the analytical shift in relation to the cinematographic documentary and the ethnographic film; the specificities of revisiting the audiovisual collection constituted by the formulation of new research problems...
October 2017: História, Ciências, Saúde—Manguinhos
Asad Ali, Xiaoying Cui, Suzanne Alexander, Darryl Eyles
Emerging evidence suggests that maternal or developmental vitamin D (DVD) deficiency is a risk factor for Autism Spectrum Disorders. A well-established association has also been found between gestational infection and increased incidence of autism. Placenta mediates the maternal immune response in respect to the foetus. The placenta is also a major source of vitamin D and locally produced vitamin D is an essential regulator of immune function during pregnancy. Here we investigate the effects of DVD-deficiency on baseline placental immune status and in response to the well-known viral and bacterial immune activating agents polyriboinosinic-polyribocytidylic acid (poly(I:C) and lipopolysaccharide (LPS)...
February 3, 2018: Journal of Steroid Biochemistry and Molecular Biology
Lindsay D Klaehn, Sarah R Hatt, David A Leske, Jonathan M Holmes
BACKGROUND: Dissociated vertical deviation (DVD) is commonly measured using a prism and alternate cover test (PACT), but some providers use a prism under cover test (PUCT). The aim of this study was to compare a standardized PUCT measurement with a PACT measurement, for assessing the magnitude of DVD. METHODS: Thirty-six patients with a clinical diagnosis of DVD underwent measurement of the angle of deviation with the PACT, fixing with the habitually fixing eye, and with PUCT, fixing both right and left eyes...
February 2, 2018: Strabismus
Eden Lowe, John Britton, Jo Cranwell
Aim: To quantify the occurrence of alcohol content, including alcohol branding, in the popular primetime television UK Reality TV show 'Geordie Shore' Series 11. Methods: A 1-min interval coding content analysis of alcohol content in the entire DVD Series 11 of 'Geordie Shore' (10 episodes). Occurrence of alcohol use, implied use, other alcohol reference/paraphernalia or branding was recorded. Results: All categories of alcohol were present in all episodes...
January 21, 2018: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
Monica Webb Hooper, Kelly Carpenter, Michael Payne, Ken Resnicow
BACKGROUND: African Americans suffer disproportionately from tobacco-related illness and have more difficulty quitting smoking than other racial/ethnic groups. Previous research indicates that African American treatment-seekers are high utilizers of tobacco quitlines, yet cessation rates via quitlines are lower relative to whites. The goal of the present study is to test the effectiveness of adding a culturally specific, video-based, adjunct to standard quitline care. It is hypothesized that the integration of an evidence-based intervention (Pathways to Freedom: Leading the Way to a Smoke-Free Community©; PTF) into quitline services will increase cessation and treatment engagement compared to control conditions, and that effects will be moderated by sociocultural factors (e...
January 10, 2018: BMC Public Health
Myles D Young, Philip J Morgan
BACKGROUND: Obesity and depression are of two of the largest contributors to the global burden of disease in men. Although lifestyle behavior change programs can improve participants' weight and depressive symptoms, the evidence is limited by a lack of male participants and a reliance on face-to-face treatment approaches, which are not accessible or appealing for many men. OBJECTIVE: This study examined the effect of a gender-tailored electronic health (eHealth) program on the depressive symptoms of a community sample of overweight and obese men with or without depression...
January 9, 2018: JMIR Mental Health
Jessica D Moorman, Kristen Harrison
Greater consumption of and access to screen media are known correlates of unhealthy sleep behavior in preschoolers. What remains unknown, however, is the role a child's media use plays in this association. Parents and guardians of U.S. preschoolers (N = 278, average child age 56 months) provided information about their child's nightly duration of sleep, daily duration of nap, quantity of screen media use, sneaky media use, and the presence of a screen media device in the bedroom. We assessed four media: television, DVD/VCRs, video games, and computer/Internet...
January 9, 2018: Health Communication
Melanie C Ruzek, Lili Huang, Ting Ting Zhang, Shaughn Bryant, Peter F Slivka, Carolyn A Cuff, Catherine Tripp, Guenter Blaich
Despite the efficacy of biologics for treatment of rheumatoid arthritis (RA), many patients show inadequate responses and likely require neutralization of multiple mediators. Neutralization of both interleukin (IL)-1β and IL-17A with monoclonal antibodies showed greater efficacy than either agent alone in a mouse arthritis model with cooperative inhibition of key inflammatory factors, IL-6, granulocyte colony stimulating factor (G-CSF) and CXC chemokine ligand (CXCL)1. Given the potential clinical benefit in RA, we generated a human dual variable domain antibody (DVD-Ig), ABBV-615, capable of simultaneous binding and neutralization of IL-1β and IL-17A...
January 8, 2018: Journal of Pharmacology and Experimental Therapeutics
Shinsuke Iida, Tatsuo Ichinohe, Atsushi Shinagawa, Kenshi Suzuki, Naoki Takezako, Masayuki Aoki
Daratumumab in combination with bortezomib and dexamethasone (DVd) has demonstrated longer progression-free survival than combination of bortezomib and dexamethasone in patients with relapsed or refractory multiple myeloma (RRMM). In this multicenter, open-label, phase-1 study, the safety, efficacy, and pharmacokinetics (PK) of DVd were evaluated in Japanese patients with RRMM. Eight patients with RRMM aged between 54 and 82 years were enrolled and treated with DVd regimen. Primary endpoints were tolerability and safety...
December 19, 2017: International Journal of Hematology
Y Bok Lee, J Hyun Lee, J Young Choi, D Soo Yu, K Do Han, Y Gyu Park
AIM: As the associations between actinic keratosis (AK) and diabetes complications in patients with diabetes mellitus (DM) have never been investigated, this study aimed to evaluate any such associations in patients with DM. METHODS: This retrospective cohort study analyzed clinical data for DM patients aged>40 years who had undergone the health examination recommended by the South Korea National Health Insurance Program between 2009 and 2012 (n=2,056,580). All of these patients were classified according to the presence of diabetic retinopathy (DR), end-stage renal disease (ESRD) and history of DVD; myocardial infarction, stroke, transient ischaemic attacks...
November 29, 2017: Diabetes & Metabolism
Anne Bruton, Amanda Lee, Lucy Yardley, James Raftery, Emily Arden-Close, Sarah Kirby, Shihua Zhu, Manimekalai Thiruvothiyur, Frances Webley, Lyn Taylor, Denise Gibson, Guiqing Yao, Mark Stafford-Watson, Jenny Versnel, Michael Moore, Steve George, Paul Little, Ratko Djukanovic, David Price, Ian D Pavord, Stephen T Holgate, Mike Thomas
BACKGROUND: Despite effective pharmacotherapy, asthma continues to impair quality of life for most patients. Non-pharmacological approaches, including breathing retraining, are therefore of great interest to patients. However, clinicians rarely advocate breathing retraining and access to this intervention is restricted for most patients due to the limited availability of suitable physiotherapists and poor integration of breathing retraining into standard care. We aimed to assess the effectiveness of a digital self-guided breathing retraining intervention...
December 13, 2017: Lancet Respiratory Medicine
Lesley Stafford, Michelle Sinclair, Jane Turner, Louise Newman, Claire Wakefield, Mei Krishnasamy, G Bruce Mann, Leslie Gilham, Kylie Mason, Paula Rauch, Julia Cannell, Penelope Schofield
Background: Parents with cancer have high rates of psychological morbidity, and their children are at risk of poor psychosocial outcomes, particularly in the context of parental distress and poor family communication. Parents express concerns about the impact of cancer on their children and report a lack of professional guidance in meeting their children's needs. Few parenting interventions exist and current interventions have extensive infrastructure demands making them unsuitable for routine use in most health settings...
2017: Pilot and Feasibility Studies
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