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https://www.readbyqxmd.com/read/28721310/a-pilot-study-to-determine-the-effect-of-an-educational-dvd-in-philippine-languages-on-cancer-clinical-trial-participation-among-filipinos-in-hawai-i
#1
Jamie Q Felicitas-Perkins, Melvin Paul Palalay, Charlene Cuaresma, Reginald Cs Ho, Moon S Chen, Julie Dang, William S Loui
We conducted an experimental pilot study in an oncology clinic in Honolulu, Hawai'i to determine the effect of a culturally-tailored educational DVD on cancer clinical trial participation among Filipino cancer patients. Thirty-seven patients participated in the study, with 17 randomized into the control group (ie, usual education) and 20 into the intervention group (ie, usual education plus educational DVD). Participants completed pre- and post-educational questionnaires with items asking about understanding of several cancer topics, behavioral outcomes, and attitudes regarding several treatment and physician related topics...
July 2017: Hawai'i Journal of Medicine & Public Health: a Journal of Asia Pacific Medicine & Public Health
https://www.readbyqxmd.com/read/28716540/developmental-vitamin-d-deficiency-alters-multiple-neurotransmitter-systems-in-the-neonatal-rat-brain
#2
James P Kesby, Karly M Turner, Suzanne Alexander, Darryl W Eyles, John J McGrath, Thomas H J Burne
BACKGROUND: Epidemiological evidence suggests that developmental vitamin D (DVD) deficiency is a risk factor for neuropsychiatric disorders, such as schizophrenia. DVD deficiency in rats is associated with altered brain structure and adult behaviours indicating alterations in dopamine and glutamate signalling. Developmental alterations in dopamine neurotransmission have also been observed in DVD-deficient rats but a comprehensive assessment of brain neurochemistry has not been undertaken...
July 14, 2017: International Journal of Developmental Neuroscience
https://www.readbyqxmd.com/read/28704915/treatment-of-diabetic-kidney-disease-current-and-future-targets
#3
REVIEW
Mi-Kyung Kim
Diabetic kidney disease (DKD) is a leading cause of end-stage renal disease in Korea and worldwide, and is a risk factor for the development of cardiovascular complications. The conventional treatments for DKD are control of blood glucose and blood pressure levels by inhibiting the renin-angiotensin system. However, the prevalence of DKD continues to increase and additional therapies are required to prevent or ameliorate the condition. Many drugs have been, or are being, developed to target the molecular mechanisms in play in DKD...
July 2017: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/28682184/-women-and-active-life-an-extended-tpb-based-multimedia-software-to-boost-and-sustain-physical-activity-and-fitness-of-iranian-women
#4
Zeinab Gholamnia-Shirvani, Fazlollah Ghofranipour, Reza Gharakhanlou, Anoshirvan Kazemnejad
Inactivity is prevalent in women, although regular physical activity (PA) has significant health benefits. Health education interventions based on multimedia software and the extended Theory of Planned Behavior (TPB) with planning may be efficacious in promoting PA. This randomized controlled trial, conducted in 2014, aimed to evaluate theory-based multimedia for increasing and maintaining PA and fitness of 130 military personnel's wives in Tehran, Iran. We randomly selected respondents by multi-stage cluster sampling...
July 6, 2017: Women & Health
https://www.readbyqxmd.com/read/28669789/self-directed-interactive-video-based-instruction-versus-instructor-led-teaching-for-myanmar-house-surgeons-a-randomized-noninferiority-trial
#5
Albert Thein Lwin, Thein Lwin, Phyu Naing, Yee Oo, David Kidd, Marcelo Cerullo, Joshua Posen, Kyaw Hlaing, Gayane Yenokyan, Kyi Kyi Thinn, Zaw Wai Soe, Kent A Stevens
OBJECTIVE: To compare self-directed interactive video-based instruction (IVBI) with instructor-led teaching in the acquisition of basic surgical skills by House Surgeons at University of Medicine 1, Yangon. DESIGN: A prospective, 1:1 randomized controlled trial was conducted. Participants were randomized into 2 teaching arms: (1) self-directed IVBI or (2) instructor-led teaching. Self-directed IVBI participants were provided with a portable DVD player that could play, fast forward, rewind, and skip through skills modules...
June 29, 2017: Journal of Surgical Education
https://www.readbyqxmd.com/read/28669433/asymptomatic-canine-degenerative-valve-disease-current-and-future-therapies
#6
REVIEW
Sonya G Gordon, Ashley B Saunders, Sonya R Wesselowski
Degenerative valve disease (DVD) is the leading cause of heart disease and congestive heart failure (CHF) in the dog. The first published consensus statement provided guidelines for diagnosis and treatment of DVD. Although treatment was not recommended in stage B1 DVD, consensus was not reached regarding evidence-based recommendations for treatment of stage B2 DVD. This article addresses the impact of new evidence on historical recommendations for stage B DVD, and gives the reader a glimpse into possible future therapies...
June 29, 2017: Veterinary Clinics of North America. Small Animal Practice
https://www.readbyqxmd.com/read/28655101/-efficacy-and-safety-of-dvd-and-vad-regimens-in-patients-with-newly-diagnosed-multiple-myeloma
#7
W J Liu, W D Wang, H Wang, J H Wang, Y Lyu
No abstract text is available yet for this article.
June 14, 2017: Zhonghua Xue Ye Xue za Zhi, Zhonghua Xueyexue Zazhi
https://www.readbyqxmd.com/read/28649416/educational-intervention-to-reduce-disease-related-to-sub-optimal-basic-hygiene-in-rwanda-initial-evaluation-and-feasibility-study
#8
Margaret A Stone, Hormisdas Ndagijimana
BACKGROUND: Despite a global reduction in morbidity related to sub-optimal water, sanitation and hygiene, the incidence of such diseases remains a significant problem in sub-Saharan Africa. This study aimed to initially assess the potential effectiveness (primarily in terms of impact on morbidity) of a simple educational intervention delivered in Rwanda. Additionally, we sought to explore feasibility relating to the practicality of evaluating and implementing this type of intervention in a low- and middle-income country...
2018: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/28628479/chronic-pain-in-high-school-students-is-associated-with-physical-activity-and-sleeping-hours-but-not-with-screen-time
#9
Anabela G Silva, Pedro Sá Couto, Alexandra Queirós, Maritza Neto, Nelson P Rocha
Background Existing studies on the association between physical activity (PA), screen based time and sleeping show conflicting results. Objective This study investigates the association between chronic pain at different body regions and self-reported PA, screen based time and sleeping hours in high school students. Subjects A total of 969 students aged 13-19 years old. Methods Participants completed a questionnaire on chronic pain, time spent in moderate and vigorous PA, screen based time watching televivsion (TV)/digital versatile discs (DVD), playing, using mobile phones and computers and sleeping hours...
June 17, 2017: International Journal of Adolescent Medicine and Health
https://www.readbyqxmd.com/read/28602711/patients-perceptions-and-attitudes-on-recurrent-prostate-cancer-and-hormone-therapy-qualitative-comparison-between-decision-aid-and-control-groups
#10
Rita Gorawara-Bhat, Siobhan O'Muircheartaigh, Supriya Mohile, William Dale
OBJECTIVE: To compare patients' attitudes towards recurrent prostate cancer (PCa) and starting hormone therapy (HT) treatment in two groups-Decision-Aid (DA) (intervention) and Standard-of-care (SoC) (Control). METHODS: The present research was conducted at three academic clinics-two in the Midwest and one in the Northeast U.S. Patients with biochemical recurrence of PCa (n=26) and follow-up oncology visits meeting inclusion criteria were randomized to either the SoC or DA intervention group prior to their consultation...
June 8, 2017: Journal of Geriatric Oncology
https://www.readbyqxmd.com/read/28585177/potent-and-conditional-redirected-t-cell-killing-of-tumor-cells-using-half-dvd-ig
#11
Philip D Bardwell, Matthew M Staron, Junjian Liu, Qingfeng Tao, Susanne Scesney, Gail Bukofzer, Luis E Rodriguez, Chee-Ho Choi, Jennifer Wang, Qing Chang, Feng Dong, Cherrie Donawho, Jieyi Wang, Christine M Grinnell, Edit Tarcsa, Charles Hutchins, Tariq Ghayur, Jijie Gu
Novel biologics that redirect cytotoxic T lymphocytes (CTLs) to kill tumor cells bearing a tumor associated antigen hold great promise in the clinic. However, the ability to safely and potently target CD3 on CTL toward tumor associated antigens (TAA) expressed on tumor cells remains a challenge of both technology and biology. Herein we describe the use of a Half DVD-Ig format that can redirect CTL to kill tumor cells. Notably, Half DVD-Ig molecules that are monovalent for each specificity demonstrated reduced non-specific CTL activation and conditional CTL activation upon binding to TAA compared to intact tetravalent DVD-Ig molecules that are bivalent for each specificity, while maintaining good drug like properties and appropriate PK properties...
June 5, 2017: Protein & Cell
https://www.readbyqxmd.com/read/28555270/critical-review-of-brain-avm-surgery-surgical-results-and-natural-history-in-2017
#12
REVIEW
Michael Kerin Morgan, Andrew Stewart Davidson, Nazih N A Assaad, Marcus Andrew Stoodley
BACKGROUND: An understanding of the present standing of surgery, surgical results and the role in altering the future morbidity and mortality of untreated brain arteriovenous malformations (bAVMs) is appropriate considering the myriad alternative management pathways (including radiosurgery, embolization or some combination of treatments), varying risks and selection biases that have contributed to confusion regarding management. The purpose of this review is to clarify the link between the incidence of adverse outcomes that are reported from a management pathway of either surgery or no intervention with the projected risks of surgery or no intervention...
May 29, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/28547942/evaluation-of-a-skin-self-examination-programme-a-four-stage-recursive-model
#13
David Rowell, Kim Huong Nguyen, Peter Baade, Monika Janda
Background: Effective skin self-examination can enable early diagnosis and treatment of skin cancer, which otherwise could result in significant morbidity and mortality. We compare the effects of watching a DVD and reading printed materials on self skin examination. Methods: Longitudinal data from the Randomized Skin Awareness Trial were analysed (n=984). The control group were provided with written materials describing how to conduct effective skin self-examination. The intervention group received additional instruction from a DVD...
April 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28531788/association-of-dietary-factors-with-severity-of-coronary-artery-disease
#14
Namita Mahalle, M K Garg, S S Naik, M V Kulkarni
BACKGROUND: Cardiovascular disease has taken epidemic proportions during past decades. Cardiovascular risk factors contribute to progression of coronary lesions, worsening the patient's prognosis. This study was planned to analyze the association of dietary factors with severity of coronary artery disease (CAD) in Indian patients. METHODS: Three hundred patients with known coronary disease above the age of 25 years were included in this study. Blood samples were collected for biochemical markers...
October 2016: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/28521606/can-video-self-modeling-improve-affected-limb-reach-and-grasp-ability-in-stroke-patients
#15
Kylie Ann Steel, Kurt Mudie, Remi Sandoval, David Anderson, Sera Dogramaci, Mohammad Rehmanjan, Ingvars Birznieks
The authors examined whether feedforward video self-modeling (FF VSM) would improve control over the affected limb, movement self-confidence, movement self-consciousness, and well-being in 18 stroke survivors. Participants completed a cup transport task and 2 questionnaires related to psychological processes pre- and postintervention. Pretest video footage of the unaffected limb performing the task was edited to create a best-of or mirror-reversed training DVD, creating the illusion that patients were performing proficiently with the affected limb...
May 19, 2017: Journal of Motor Behavior
https://www.readbyqxmd.com/read/28511650/pain-pain-intensity-and-pain-disability-in-high-school-students-are-differently-associated-with-physical-activity-screening-hours-and-sleep
#16
Anabela G Silva, Pedro Sa-Couto, Alexandra Queirós, Maritza Neto, Nelson P Rocha
BACKGROUND: Studies exploring the association between physical activity, screen time and sleep and pain usually focus on a limited number of painful body sites. Nevertheless, pain at different body sites is likely to be of different nature. Therefore, this study aims to explore and compare the association between time spent in self-reported physical activity, in screen based activities and sleeping and i) pain presence in the last 7-days for 9 different body sites; ii) pain intensity at 9 different body sites and iii) global disability...
May 16, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28510770/inferior-oblique-overaction-anterior-transposition-versus-myectomy
#17
Zhale Rajavi, Mohadeseh Feizi, Narges Behradfar, Mehdi Yaseri, Shima Sayanjali, Tahmine Motevaseli, Hamideh Sabbaghi, Mohammad Faghihi
PURPOSE: To compare the efficacy of inferior oblique myectomy and anterior transposition for correcting inferior oblique overaction (IOOA). METHODS: This retrospective study was conducted on 56 patients with IOOA who had either myectomy or anterior transposition of the inferior oblique muscle from 2010 to 2015. The authors compared preoperative and postoperative inferior oblique muscle function grading (-4 to +4) as the main outcome measure and vertical and horizontal deviation, dissociated vertical deviation (DVD), and A- and V-pattern between the two surgical groups as secondary outcomes...
May 15, 2017: Journal of Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28499843/magnetic-resonance-imaging-in-dissociated-strabismus-complex-demonstrates-generalized-hypertrophy-of-rectus-extraocular-muscles
#18
Ghada Z Rajab, Soh Youn Suh, Joseph L Demer
BACKGROUND: Dissociated strabismus complex (DSC) is an enigmatic form of strabismus that includes dissociated vertical deviation (DVD) and dissociated horizontal deviation (DHD). We employed magnetic resonance imaging (MRI) to evaluate the extraocular muscles in DSC. METHODS: We studied 5 patients with DSC and mean age of 25 years (range, 12-42 years), and 15 age-matched, orthotropic control subjects. All patients had DVD; 4 also had DHD. We employed high-resolution, surface coil MRI with thin, 2 mm slices and central target fixation...
June 2017: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28449637/the-effect-of-a-dynamic-chair-on-seated-energy-expenditure
#19
Aoife Synnott, Wim Dankaerts, Jan Seghers, Helen Purtill, Kieran O'Sullivan
Dynamic sitting approaches have been advocated to increase seated energy expenditure with the view of lessening the sedentary nature of the task. This study compared energy expenditure (EE) and overall body discomfort on a novel dynamic chair with a standard office chair. Fifteen pain-free participants completed a DVD viewing task on both chairs in a randomised order. Energy expenditure and discomfort were collected simultaneously. Linear mixed models were used to analyse steady-state EE recorded on each of the chairs...
May 5, 2017: Ergonomics
https://www.readbyqxmd.com/read/28445854/balance-training-in-individuals-with-parkinson-s-disease-therapist-supervised-vs-home-based-exercise-programme
#20
Elizabeth Maria Atterbury, Karen Estelle Welman
BACKGROUND: Poor locomotion and balance in Parkinson's disease (PD) often diminishes independence. Accordingly, gait is considered one of the most relevant rehabilitation outcomes, and home-based balance exercises might be a viable mode of exercise delivery for individuals with PD. However, research on PD interventions rarely indicate best practices to deliver exercises. Therefore, this study endeavoured to compare the efficacy of a home-based and therapist-supervised balance programme on gait parameters, dynamic balance, balance confidence and motivation in individuals diagnosed with PD...
April 4, 2017: Gait & Posture
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