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Liver robotic

Giovanni Battista Levi Sandri, Edoardo De Werra, Gianluca Mascianà, Francesco Guerra, Gabriele Spoletini, Quirino Lai
Minimally invasive surgical approaches in transplantation are gaining increasing interest, and many centers are reporting their, mainly laparoscopic, experiences. Robotic surgery (RS) has some hypothetical advantages over traditional laparoscopy, and has been successfully applied, although infrequently to organ transplantation. Our goal was to review and critique the publications reporting RS use in organ transplantation. Most of the RS experience has been with living renal donor organ procurement and, to a lesser extent, with RS procedures in the transplant recipient...
October 11, 2016: Clinical Transplantation
M N Wasson, P Magtibay, J Magrina
No abstract text is available yet for this article.
November 2015: Journal of Minimally Invasive Gynecology
C Salloum, C Lim, A Malek, P Compagnon, D Azoulay
Surgery using a robotic platform is expanding rapidly today, with a notable surge since its authorization on the international medical market by the US Food and Drug Administration in 2000. The first hepatectomy by a robotic approach was reported in 2002, 10 years after the first laparoscopic hepatectomy. Yet, in hepatic surgery, series are scarce and the lack of relevant data in the literature is an obstacle to the development of robot-assisted laparoscopic hepatectomy (RALH). Based on a review of the literature, this update focuses on current indications, short-term and oncologic outcomes following RALH...
September 21, 2016: Journal of Visceral Surgery
Hideo Takahashi, Nisar Zaidi, Eren Berber
BACKGROUND: There has been a recent interest in the use of Indocyanine green (ICG) imaging. The aim of this study is to review our initial experience in liver surgery. METHODS: ICG fluorescent imaging was used in 15 patients undergoing surgical treatment of their liver tumors between 2015 and 2016. ICG imaging was initially performed, followed by intraoperative ultrasound (IOUS). Findings on fluorescence were compared with preoperative cross-sectional imaging and IOUS...
October 2016: Journal of Surgical Oncology
Ibrahim Nassour, Patricio M Polanco
Minimally invasive surgery has been cautiously introduced in surgical oncology over the last two decades due to a concern of compromised oncological outcomes. Recently, it has been adopted in liver surgery for colorectal metastases. Colorectal cancer is a major cause of cancer-related death in the USA. In addition, liver metastasis is the most common site of distant disease and its resection improves survival. While open resection was the standard of care, laparoscopic liver surgery has become the standard of care for minor liver resections...
April 2016: Current Colorectal Cancer Reports
Robert J Cerfolio, Benjamin Wei, Mary T Hawn, Douglas J Minnich
Minimally invasive esophagectomy with intrathoracic dissection and anastomosis is increasingly performed. Our objectives are to report our operative technique, early results and lessons learned. This is a retrospective review of 85 consecutive patients who were scheduled for minimally invasive Ivor Lewis esophagectomy (laparoscopic or robotic abdominal and robotic chest) for esophageal cancer. Between 4/2011 and 3/2015, 85 (74 men, median age: 63) patients underwent robotic Ivor Lewis esophageal resection. In all, 64 patients (75%) had preoperative chemoradiotherapy, 99% had esophageal cancer, and 99% had an R0 resection...
2016: Seminars in Thoracic and Cardiovascular Surgery
Mashaal Dhir, Mazen S Zenati, James C Padussis, Heather L Jones, Samantha Perkins, Amber K Clifford, Jennifer Steve, Melissa E Hogg, Haroon A Choudry, Matthew P Holtzman, Herbert J Zeh, James F Pingpank, David L Bartlett, Amer H Zureikat
BACKGROUND: Hepatic artery infusion (HAI) chemotherapy can be combined with systemic chemotherapy for the treatment of isolated unresectable colorectal liver metastases (IU-CRLM) and intrahepatic cholangiocarcinoma (U-ICC). However, HAI pump placement requires a major laparotomy that may be associated with morbidity. We hypothesized that the computer-assisted robotic platform would be well suited for this procedure and report the first single institutional case series of robotic assisted HAI pump placement for primary and secondary malignancies of the liver...
September 2016: Journal of Surgical Oncology
David J Kinahan, Philip L Early, Abhishek Vembadi, Eoghan MacNamara, Niamh A Kilcawley, Thomas Glennon, Dermot Diamond, Dermot Brabazon, Jens Ducrée
We introduce a novel instrument controlled valving scheme for centrifugal platforms which is based upon xurography. In a first approach, which is akin to previously presented event-triggered flow control, the valves are composed of a pneumatic chamber sealed by a dissolvable film (DF) and by a pierceable membrane. Liquid is initially prevented from wetting the DF by the counter pressure of a trapped gas. Via a channel, this pocket is pneumatically connected to a vent, sealed by the pierceable membrane, located on the top surface of the disc...
September 21, 2016: Lab on a Chip
Po-Da Chen, Chao-Ying Wu, Rey-Heng Hu, Cheng-Maw Ho, Po-Huang Lee, Hong-Shiee Lai, Ming-Tsan Lin, Yao-Ming Wu
Right hepatectomy for living liver donor via a pure minimally invasive approach is a challenging procedure and only few cases have been reported. Between May 2013 and August 2015, 13 patients underwent robotic living donor right hepatectomy in our institute, and 54 patients received open surgery. In this series, no conversion was conducted for robotic donor right hepatectomy. The two groups shared similar blood loss (169 vs. 146 ml), complication rate (7.7 vs. 9.3%) and recovery of donor liver function. The robotic group need longer operation time (596 vs...
August 10, 2016: Liver Transplantation
Pier Cristoforo Giulianotti, Francesco Maria Bianco, Despoina Daskalaki, Luis Fernando Gonzalez-Ciccarelli, Jihun Kim, Enrico Benedetti
Minimally invasive surgery for liver resections has a defined role and represents an accepted alternative to open techniques for selected cases. Robotic technology can overcome some of the disadvantages of the laparoscopic technique, mainly in the most complex cases. Precise dissection and microsuturing is possible, even in narrow operative fields, allowing for a better dissection of the hepatic hilum, fine lymphadenectomy, and biliary reconstruction even with small bile ducts and easier bleeding control. This technique has the potential to allow for a greater number of major resections and difficult segmentectomies to be performed in a minimally invasive fashion...
August 2016: Hepatobiliary Surgery and Nutrition
Michele Diana, Yu-Yin Liu, Raoul Pop, Seong-Ho Kong, Andras Legnèr, Remy Beaujeux, Patrick Pessaux, Luc Soler, Didier Mutter, Bernard Dallemagne, Jacques Marescaux
BACKGROUND: Intraoperative liver segmentation can be obtained by means of percutaneous intra-portal injection of a fluorophore and illumination with a near-infrared light source. However, the percutaneous approach is challenging in the minimally invasive setting. We aimed to evaluate the feasibility of fluorescence liver segmentation by superselective intra-hepatic arterial injection of indocyanine green (ICG). MATERIALS AND METHODS: Eight pigs (mean weight: 26...
August 5, 2016: Surgical Endoscopy
Mashaal Dhir, Deepa Magge, Stephanie Novak, David L Bartlett, Amer H Zureikat
BACKGROUND: Hepatic artery infusion (HAI) chemotherapy is an effective regional therapy for unresectable colorectal liver metastases (U-CRLM).1 (,) 2 One of its limitations is the need for a laparotomy, which can delay the use of systemic therapy.3 Here, we describe a purely robotic technique for placement of an HAI pump (Fig 1). PATIENT: A 62-year-old male presented with a symptomatic ascending colon cancer and multiple bilobar unresectable liver metastases. He underwent laparoscopic right colectomy followed by six cycles of FOLFOXIRI and bevacizumab with stable disease by RECIST (Response Evaluation Criteria in Solid Tumors) criteria, and also underwent robotic HAI pump placement...
August 5, 2016: Annals of Surgical Oncology
R Memeo, V De Blasi, O Perotto, D Mutter, J Marescaux, P Pessaux
BACKGROUND: An expert consensus meeting had defined the standard lymphadenectomy during pancreatoduodenectomy for an adenocarcinoma of the head of the pancreas. There is a controversy regarding the possibility to perform this optimal lymphadenectomy by minimally invasive approach. PATIENTS: The patient was a 68-year-old man with the diagnosis of an adenocarcinoma of the head of the pancreas. The 3D reconstructions evidenced the existence of a right hepatic artery...
July 26, 2016: Annals of Surgical Oncology
Marius L Calin, Aziz Sadiq, Gabriel Arevalo, Rocio Fuentes, Vincent L Flanders, Niraj Gupta, Baongoc Nasri, Kirpal Singh
INTRODUCTION: Surgery for liver metastases in pancreatic neuroendocrine tumor (PNET) improves overall survival rate. We present the first case report for robotic multivisceral resection of distal pancreas, spleen, and left liver for metastatic PNET. MATERIALS AND METHODS: We present a case of 52-year-old female diagnosed with PNET in the pancreatic neck metastatic to the liver, responding to somatostatin and bland embolization, who underwent surgical debulking using da Vinci robotic platform...
October 2016: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
Jon M Carthy, Martin Stöter, Claudia Bellomo, Michael Vanlandewijck, Angelos Heldin, Anita Morén, Dimitris Kardassis, Timothy C Gahman, Andrew K Shiau, Marc Bickle, Marino Zerial, Carl-Henrik Heldin, Aristidis Moustakas
Plasticity in epithelial tissues relates to processes of embryonic development, tissue fibrosis and cancer progression. Pharmacological modulation of epithelial transitions during disease progression may thus be clinically useful. Using human keratinocytes and a robotic high-content imaging platform, we screened for chemical compounds that reverse transforming growth factor β (TGF-β)-induced epithelial-mesenchymal transition. In addition to TGF-β receptor kinase inhibitors, we identified small molecule epithelial plasticity modulators including a naturally occurring hydroxysterol agonist of the liver X receptors (LXRs), members of the nuclear receptor transcription factor family...
2016: Scientific Reports
Paramin Muangkaew, Anusak Yiengpruksawan
INTRODUCTION: Blood loss is associated with postoperative morbidity and mortality. Outflow control could be used concomitantly with inflow control for maximum reduction in blood loss during parenchymal transection. However, in left hepatectomy (LH) and left lateral sectionectomy (LLS), extrahepatic control of the left hepatic vein (LHV) is still less commonly used. Some authors reported extrahepatic LHV control technique using ligamentum venosum (LV) in open or laparoscopic surgery, but no reports of this technique in robotic surgery have been found...
September 2016: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
Sae Byeol Choi, Sang Yong Choi
Recent advances in minimally invasive surgery include laparoscopic and robotic surgery. These surgical techniques have changed the paradigm of surgical treatment for hepatobiliary diseases. Minimally invasive surgery has the advantages of minimal wound extension for cosmetic effect, early postoperative recovery, and few postoperative complications in patients. For laparoscopic liver resection, the indications have been expanded and oncological outcome was proven to be similar with open surgery in the malignant disease...
June 2016: Kaohsiung Journal of Medical Sciences
Derek T Bernacki, Steven M Bryce, Jeffrey C Bemis, David Kirkland, Stephen D Dertinger
Previous work with a diverse set of reference chemicals suggests that an in vitro multiplexed flow cytometry-based assay (MultiFlow™ DNA Damage Kit-p53, γH2AX, Phospho-Histone H3) can distinguish direct-acting clastogens and aneugens from nongenotoxicants (Bryce SM et al. []: Environ Mol Mutagen 57:171-189). This work extends this line of investigation to include compounds that require metabolic activation to form reactive electrophiles. For these experiments, TK6 cells were exposed to 11 promutagens and 37 presumed nongenotoxicants in 96 well plates...
August 2016: Environmental and Molecular Mutagenesis
Rafael Garcia, Kita Sallabanda, Iciar Santa-Olalla, Jose Luis Lopez Guerra, Lijia Avilés, Morena Sallabanda, Eleonor Rivin, José Samblás
Modern technologies allow the delivery of high radiation doses to intramedullary spinal cord metastases while lowering the dose to the neighboring organs at risk. Whether this dosimetric advantage translates into clinical benefit is not well known. This study evaluates the acute and late toxicity outcomes in a patient treated with robotic radiosurgery for an intramedullary spinal cord metastasis. A 50-year-old woman diagnosed in May 2006 with invasive ductal carcinoma of the right breast T2N3M1 (two liver metastases) received chemotherapy with a complete response...
2016: Curēus
Maria Marsico, Tommaso Gabbani, Lorenzo Livi, Maria Rosa Biagini, Andrea Galli
AIM: To assess how the application of different types of markers affects the tracking accuracy of CyberKnife's. METHODS: Fifteen patients were recruited and subjected to the ultrasound-guided placement of markers. Two different type of needles 25 gauge (G) and 17 G containing two different fiducial marker, gold notched flexible anchor wire 0.28 mm × 10 mm (25 G needle) and gold cylindrical grain 1 mm × 4 mm (17 G), were used. Seven days after the procedure, a CyberKnife planning computed tomography (CT) for the simulation of radiation treatment was performed on all patients...
June 18, 2016: World Journal of Hepatology
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