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https://www.readbyqxmd.com/read/27903184/microinvasive-tumor-endoresection-in-combination-with-ocular-stereotactic-radiosurgery
#1
Oleg A Sinyavskiy, Roman L Troyanovsky, Pavel I Ivanov, Alexandr S Golovin, Andrey V Tibilov, Svetlana N Solonina, Anna M Astapenko, Irina S Zubatkina
OBJECTIVE The use of Gamma Knife radiosurgery (GKRS) as monotherapy in the treatment of uveal melanoma (UM) allows clinicians to achieve high local tumor control with low recurrence but does not prevent secondary enucleation due to glaucoma in cases of large tumors. The authors analyzed indications for tumor endoresection (ER), the time interval between irradiation and surgery, and the features and results of performing ER for UM after GKRS. METHODS Thirty-seven patients between 28 and 78 years of age (16 male and 11 female patients) with UM underwent GKRS with a dose of 70 to 80 Gy that was applied to the center of the tumor with complete immobilization of the eye during the procedure...
December 2016: Journal of Neurosurgery
https://www.readbyqxmd.com/read/27875568/gated-volumetric-modulated-arc-therapy-vs-tumor-tracking-cyberknife-radiotherapy-as-stereotactic-body-radiotherapy-for-hepatocellular-carcinoma-a-dosimetric-comparison-study-focused-on-the-impact-of-respiratory-motion-managements
#2
KyoungJun Yoon, Jungwon Kwak, Byungchul Cho, Jin-Hong Park, Sang Min Yoon, Sang-Wook Lee, Jong Hoon Kim
PURPOSE: To assess the potential dosimetric benefits associated with the CyberKnife (CK) tumor tracking capability, wherein an extra margin for respiratory tumor motion is not required, when compared to respiratory-gated volumetric-modulated arc therapy (VMAT) for hepatocellular carcinoma (HCC). METHODS: Twenty-nine HCC patients previously treated with double-arc VMAT were enrolled. In each VMAT plan, the individual internal target volume (ITV) margin around the tumor was determined by measuring its motion over 30-70% of respiratory phases using four-dimensional computed tomography, followed by a 5-mm isotropic margin for the planning target volume (PTV)...
2016: PloS One
https://www.readbyqxmd.com/read/27870704/clinical-outcomes-for-stereotactic-ablative-radiotherapy-in-oligometastatic-and-oligoprogressive-gynecological-malignancies
#3
Shane Mesko, Kiri Sandler, Joshua Cohen, Gottfried Konecny, Michael Steinberg, Mitchell Kamrava
OBJECTIVES: We report single-institution clinical outcomes of women treated with stereotactic ablative radiotherapy (SABR) for oligometastatic or progressive gynecological malignancies. MATERIALS AND METHODS: From 2009 to 2015, 47 lesions from 28 patients were treated with SABR and retrospectively analyzed. All patients had oligometastatic (93%) or oligoprogressive (7%) disease. Primary cancer diagnoses were 15 ovarian, 8 endometrial, 2 cervical, 2 vaginal, and 1 uterine carcinosarcoma...
November 17, 2016: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/27865544/central-liver-toxicity-after-sbrt-an-expanded-analysis-and-predictive-nomogram
#4
Diego A S Toesca, Evan C Osmundson, Rie von Eyben, Jenny L Shaffer, Albert C Koong, Daniel T Chang
PURPOSE: To further explore the correlation of central biliary tract (cHBT) radiation doses with hepatobiliary toxicity (HBT) after stereotactic body radiation therapy (SBRT) in a larger patient dataset. METHODS: We reviewed the treatment and outcomes of all patients who received SBRT for primary liver cancer (PLC) and metastatic liver tumors between July 2004 and November 2015 at our institution. The cHBT was defined as isotropic expansions (5, 10, 15, 20 and 25mm) from the portal vein (PV)...
November 16, 2016: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/27806580/robotic-intrafractional-us-guidance-for-liver-sabr-system-design-beam-avoidance-and-clinical-imaging
#5
Jeffrey Schlosser, Ren Hui Gong, Ralf Bruder, Achim Schweikard, Sungjune Jang, John Henrie, Aya Kamaya, Albert Koong, Daniel T Chang, Dimitre Hristov
PURPOSE: To present a system for robotic 4D ultrasound (US) imaging concurrent with radiotherapy beam delivery and estimate the proportion of liver stereotactic ablative body radiotherapy (SABR) cases in which robotic US image guidance can be deployed without interfering with clinically used VMAT beam configurations. METHODS: The image guidance hardware comprises a 4D US machine, an optical tracking system for measuring US probe pose, and a custom-designed robot for acquiring hands-free US volumes...
November 2016: Medical Physics
https://www.readbyqxmd.com/read/27762601/stereotactic-ct-guided-percutaneous-microwave-ablation-of-liver-tumors-with-the-use-of-high-frequency-jet-ventilation-an-accuracy-and-procedural-safety-study
#6
Jennie Engstrand, Grzegorz Toporek, Piotr Harbut, Eduard Jonas, Henrik Nilsson, Jacob Freedman
OBJECTIVE: The purpose of the present study is to evaluate the accuracy and safety of antenna placement performed with the use of a CT-guided stereotactic navigation system for percutaneous ablation of liver tumors and to assess the safety of high-frequency jet ventilation for target motion control. MATERIALS AND METHODS: Twenty consecutive patients with malignant liver lesions for which surgical resection was contraindicated or that were not readily visible on ultrasound or not accessible by ultrasound guidance were included in the study...
October 20, 2016: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/27756535/dosimetric-comparison-of-flattened-and-unflattened-beams-for-stereotactic-body-radiation-therapy-impact-of-the-size-of-the-ptv-on-dynamic-conformal-arc-and-volumetric-modulated-arc-therapy
#7
Laure Vieillevigne, Sandra Bessieres, Monia Ouali, Christel Lanaspeze
PURPOSE: Flattening filter free (FFF) beams are frequently used for stereotactic body radiation therapy with various treatment modalities: conventional static fields, dynamic conformal arc (DCA) or Rapid Arc (RA). The goal of this study was to obtain some criteria to enable a conscious choice of the employment of FFF beams and of the DCA or RA technique, depending on the PTV size. METHODS AND MATERIALS: 24 PTVs from 1.52cm(3) to 445.24cm(3) were studied in various sites: virtual phantom, lung and liver...
November 2016: Physica Medica: PM
https://www.readbyqxmd.com/read/27742541/simulated-online-adaptive-magnetic-resonance-guided-stereotactic-body-radiation-therapy-for-the-treatment-of-oligometastatic-disease-of-the-abdomen-and-central-thorax-characterization-of-potential-advantages
#8
Lauren Henke, Rojano Kashani, Deshan Yang, Tianyu Zhao, Olga Green, Lindsey Olsen, Vivian Rodriguez, H Omar Wooten, H Harold Li, Yanle Hu, Jeffrey Bradley, Clifford Robinson, Parag Parikh, Jeff Michalski, Sasa Mutic, Jeffrey R Olsen
PURPOSE: To characterize potential advantages of online-adaptive magnetic resonance (MR)-guided stereotactic body radiation therapy (SBRT) to treat oligometastatic disease of the non-liver abdomen and central thorax. METHODS AND MATERIALS: Ten patients treated with RT for unresectable primary or oligometastatic disease of the non-liver abdomen (n=5) or central thorax (n=5) underwent imaging throughout treatment on a clinical MR image guided RT system. The SBRT plans were created on the basis of tumor/organ at risk (OAR) anatomy at initial computed tomography simulation (PI), and simulated adaptive plans were created on the basis of observed MR image set tumor/OAR "anatomy of the day" (PA)...
December 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27681222/stereotactic-radiation-therapy-for-hepatic-malignancies
#9
Jeffrey Meyer
Management of primary and secondary tumors of the liver is a complex undertaking involving multi- disciplinary input. Radiation therapy has held a minor role in the treatment of liver tumors, but with technological innovations and the growth of the field of stereotactic body radiation therapy (SBRT), this role is evolving. In this review, I discuss the issues of radiation-induced hepatic toxicity, the planning of liver SBRT treatments, clinical results with SBRT, its place amongst other non-surgical ablative treatments, and potential future avenues of investigation...
September 28, 2016: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/27675785/safety-and-efficacy-of-stereotactic-body-radiation-therapy-of-accelerated-hypofractionation-for-hepatocellular-carcinoma-in-the-setting-of-advanced-liver-dysfunction
#10
N Nabavizadeh, J G Waller, R Fain, Y Chen, D A Elliott, B Mullins, I Patel, C Degnin, B A Dyer, K Farsad, J A Tanyi, M Fuss, C R Thomas, A Y Hung
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27675784/micrornas-predict-liver-toxicity-in-patients-receiving-stereotactic-body-radiation-therapy-for-hepatocellular-carcinoma
#11
K C Cuneo, Y Sun, M Schipper, M Tewari, R K Ten Haken, T S Lawrence, M Feng
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27675632/combined-analysis-of-2-prospective-trials-of-individualized-adaptive-stereotactic-body-radiation-therapy-for-the-treatment-of-hepatocellular-carcinoma-hcc-or-liver-metastases
#12
W C Jackson, K Suresh, M Schipper, L Bazzi, E Ben-Josef, K C Cuneo, M M Matuszak, P Neehar, T H Welling, R K Ten Haken, T S Lawrence, M Feng
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27675382/motion-mitigation-appears-to-decrease-the-risk-of-chest-wall-morbidity-for-tumors-located-3-cm-from-the-chest-wall-during-liver-stereotactic-body-radiation-therapy
#13
A M Chhabra, B Zhang, P Mohindra, M D Chuong, W F Regine, S J Feigenberg
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27675294/evaluation-of-kv-cone-beam-computed-tomography-based-setup-errors-in-stereotactic-body-radiation-therapy-for-liver-cancer
#14
T Li, F Li, D A Clump, D E Heron, M S Huq
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27675249/using-a-knowledge-based-planning-model-for-quality-assurance-of-liver-stereotactic-body-radiation-therapy-plans
#15
H C Gits, J Dow, M Feng, M M Matuszak
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27675228/a-monoscopic-x-ray-image-based-position-monitoring-system-for-liver-stereotactic-body-radiation-therapy
#16
S Arumugam, M T Lee, M Sidhom, A Xing, L Holloway
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27675062/a-mice-radiation-induced-liver-disease-model-for-stereotactic-body-radiation-therapy-validated-in-patients-with-hepatocellular-carcinoma
#17
Z F Wu, J Y Zhang, X Y Shen, L Y Zhou, Y B Gao, Y Hu, Z C Zeng
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27674954/systematic-review-of-patient-reported-quality-of-life-following-stereotactic-ablative-body-radiation-therapy-for-primary-and-metastatic-liver-cancer
#18
A Mutsaers, J Greenspoon, C Walker-Dilks, A Swaminath
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27674947/acute-quality-of-life-changes-after-stereotactic-ablative-radiation-therapy-for-liver-metastasis-a-prospective-cohort-analysis
#19
J Helou, I Thibault, W Chu, P Munoz, D Erler, G Rodrigues, A Warner, K Chan, E Chow, R Korol, M T Davidson, H T Chung
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27674076/combined-stereotactic-body-radiation-treatment-and-bevacizumab-as-a-radiosensitizer-for-colorectal-liver-metastases
#20
P Munoz Schuffenegger, Y J Ko, L Milot, W Chu, G Czarnota, H T Chung
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
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