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José Luis Rodríguez-Chávez, Verónica Egas, Edelmira Linares, Robert Bye, Tzasna Hernández, Francisco J Espinosa-García, Guillermo Delgado
ETHNOPHARMACOLOGICAL RELEVANCE: Heterotheca inuloides Cass. (Asteraceae) has been traditionally used to treat a wide range of diseases in Mexico in the treatment of rheumatism, topical skin inflammation, muscular pain colic, and other painful conditions associated with inflammatory processes, additionally has been used to treat dental diseases, and gastrointestinal disorders. This species has also been used for the treatment of cancer and diabetes. This review provides up-to-date information on the botanical characterization, traditional uses, chemical constituents, as well as the biolological activities of H...
November 12, 2016: Journal of Ethnopharmacology
Marta Marzotto, Clara Bonafini, Debora Olioso, Anna Baruzzi, Laura Bettinetti, Francesca Di Leva, Elisabetta Galbiati, Paolo Bellavite
Arnica montana (Arnica m.) is used for its purported anti-inflammatory and tissue healing actions after trauma, bruises, or tissue injuries, but its cellular and molecular mechanisms are largely unknown. This work tested Arnica m. effects on gene expression using an in vitro model of macrophages polarized towards a "wound-healing" phenotype. The monocyte-macrophage human THP-1 cell line was cultured and differentiated with phorbol-myristate acetate and Interleukin-4, then exposed for 24h to Arnica m. centesimal (c) dilutions 2c, 3c, 5c, 9c, 15c or Control...
2016: PloS One
Arnica Karuna, Francesco Masia, Paola Borri, Wolfgang Langbein
In this work, we demonstrate quantitative volume determination of chemical components in three dimensions using hyperspectral coherent anti-Stokes Raman scattering microscopy, phase-corrected Kramers-Kronig retrieval of the coherent anti-Stokes Raman scattering susceptibility and factorization into concentration of chemical components. We investigate the influence of the refractive index contrast between water and polymer beads (polystyrene and polymethylmethacrylate), showing that it leads mainly to concentration errors, while the spectral error is less affected...
September 2016: Journal of Raman Spectroscopy: JRS
Debora Olioso, Marta Marzotto, Clara Bonafini, Maurizio Brizzi, Paolo Bellavite
No abstract text is available yet for this article.
2016: Frontiers in Immunology
Salvatore Chirumbolo, Geir Bjørklund
No abstract text is available yet for this article.
2016: Frontiers in Immunology
J Saúl García-Pérez, Sara P Cuéllar-Bermúdez, Alejandra Arévalo-Gallegos, José Rodríguez-Rodríguez, Hafiz M N Iqbal, Roberto Parra-Saldivar
Supercritical fluid extraction (SFE) is a sustainable technique used for the extraction of lipophilic metabolites such as pigments and fatty acids. Arnica plant is considered a potential candidate material with high antioxidant and antimicrobial activities. Therefore, in this study, a locally available Heterotheca inuloides, also known as Mexican arnica, was analyzed for the extraction of high-value compounds. Based on different pressure (P), temperature (T), and co-solvent (CoS), four treatments (T) were prepared...
2016: International Journal of Molecular Sciences
Tiphaine Maurice, Diethart Matthies, Serge Muller, Guy Colling
Due to land-use intensification, lowland and colline populations of many plants of nutrient-poor grasslands have been strongly fragmented in the last decades, with potentially negative consequences for their genetic diversity and persistence. Populations in mountains might represent a genetic reservoir for grassland plants, because they have been less affected by land-use changes. We studied the genetic structure and diversity of colline and montane Vosges populations of the threatened perennial plant Arnica montana in western central Europe using AFLP markers...
August 12, 2016: AoB Plants
Milka Todorova, Antoaneta Trendafilova, Antonina Vitkova, Maria Petrova, Ely Zayova, Daniela Antonova
The amount of sesquiterpene lactones and the lactone profile of Arnica montana L. in flowering and seed formation stages in vitro and in vivo propagated from seeds of German, Ukrainian, and Austrian origin and grown in two experimental fields were studied. It was found that in vitro propagated 2-year plants in full flowering stage accumulated higher amount of lactones in comparison to in vivo propagated 3-year plants and to the seed formation stage, respectively. Helenalins predominated in in vivo propagated 2-year or in vitro propagated 3-year plants...
August 2016: Chemistry & Biodiversity
Denise C E van Exsel, Shariselle M W Pool, Jeroen H van Uchelen, Mireille A Edens, Berend van der Lei, Wynand B W H Melenhorst
BACKGROUND: It has been suggested that arnica can reduce postoperative edema and ecchymosis associated with cosmetic surgical procedures and improve outcome. Despite a high incidence of arnica use among upper blepharoplasty patients, evidence to support its treatment effect is lacking. The authors performed a randomized, double-blind, placebo-controlled trial to investigate the efficacy of arnica ointment after upper blepharoplasty. METHODS: One hundred thirty-six bilateral upper blepharoplasty patients were randomized between arnica ointment 10% and placebo ointment...
July 2016: Plastic and Reconstructive Surgery
Debora Olioso, Marta Marzotto, Clara Bonafini, Maurizio Brizzi, Paolo Bellavite
BACKGROUND: Arnica montana is a popular traditional remedy widely used in complementary medicine, also for its wound healing properties. Despite its acknowledged action in clinical settings at various doses, the molecular aspects relating to how A. montana promotes wound healing remain to be elucidated. To fill this gap, we evaluated the whole plant extract, in a wide range of dilutions, in THP-1 human cells, differentiated into mature macrophages and into an alternative IL-4-activated phenotype involved in tissue remodelling and healing...
May 2016: Homeopathy: the Journal of the Faculty of Homeopathy
Ghazaleh Ahmadizenouz, Behnaz Esmaeili, Arnica Taghvaei, Zahra Jamali, Toloo Jafari, Farshid Amiri Daneshvar, Soraya Khafri
Background. Repairing aged composite resin is a challenging process. Many surface treatment options have been proposed to this end. This study evaluated the effect of different surface treatments on the shear bond strength (SBS) of nano-filled composite resin repairs. Methods. Seventy-five cylindrical specimens of a Filtek Z350XT composite resin were fabricated and stored in 37°C distilled water for 24 hours. After thermocycling, the specimens were divided into 5 groups according to the following surface treatments: no treatment (group 1); air abrasion with 50-μm aluminum oxide particles (group 2); irradiation with Er:YAG laser beams (group 3); roughening with coarse-grit diamond bur + 35% phosphoric acid (group 4); and etching with 9% hydrofluoric acid for 120 s (group 5)...
2016: Journal of Dental Research, Dental Clinics, Dental Prospects
Derek Ho, Jared Jagdeo, Heidi A Waldorf
BACKGROUND: The management of postprocedure skin care is of significant interest to dermatologists and other physicians. Ecchymosis and edema are common temporary postprocedure unwanted effects. Two botanically-derived products, arnica and bromelain, are used internationally by physicians to limit ecchymosis and edema that occur secondary to cosmetic, laser, and surgical skin procedures. OBJECTIVE: The authors review the published literature and provide evidence-based recommendations on arnica and bromelain for prevention and treatment of postprocedure ecchymosis and edema...
April 2016: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
Dimitrina Zh Zheleva-Dimitrova, Vessela Balabanova, Reneta Gevrenova, Irini Doichinova, Antonina Vitkova
INTRODUCTION: Arnica montana flowers have a long history as herbal medicines for external use on injuries and rheumatic complaints. OBJECTIVE: To investigate Arnicae flos of cultivated accessions from Bulgaria, Poland, Germany, Finland, and Pharmacy store for phenolic derivatives and sesquiterpene lactones (STLs). MATERIALS AND METHODS: Samples of Arnica from nine origins were prepared by ultrasound-assisted extraction with 80% methanol for phenolic compounds analysis...
October 2015: Pharmacognosy Magazine
Massimo Fioranelli, Maria Bianchi, Maria G Roccia, Veronica Di Nardo
BACKGROUND: The purpose of the study was to evaluate the effectiveness of the treatment with one tablet a day of a low dose multicomponent medication (Arnica comp.-Heel® tablets) with anti-inflammatory properties in order to reduce the risk of cardiovascular events in patients with clinically stable coronary disease. The presence of inflammatory cells in atherosclerotic plaques of patients with stable coronary disease indicates the possibility to act by inhibiting the inflammatory phenomenon with Arnica comp...
February 2016: Minerva Cardioangiologica
Krystyna Kromer, Agnieszka Kreitschitz, Thomas Kleinteich, Stanislav N Gorb, Antoni Szumny
Arnica, a genus including the medicinal species A. montana, in its Arbo variety, and A. chamissonis, is among the plants richest in essential oils used as pharmaceutical materials. Despite its extensive use, the role of anatomy and histochemistry in the internal secretory system producing the essential oil is poorly understood. Anatomical sections allowed differentiation between two forms of secretory structures which differ according to their distribution in plants. The first axial type is connected to the vascular system of all vegetative organs and forms canals lined with epithelial cells...
May 2016: Plant & Cell Physiology
Gokce Simsek, Elif Sari, Rahmi Kilic, Nuray Bayar Muluk
BACKGROUND: The purpose of this study was to investigate the effects of local arnica and mucopolysaccharide polysulfate treatment on the regression of postoperative edema and ecchymosis in patients who have undergone open technique rhinoplasty. METHOD: One hundred eight patients were included in the study. Participants were randomized into three groups, all of whom had undergone rhinoplasty. Group 1 (n = 36) received postoperative arnica cream treatment, and group 2 (n = 36) received postoperative mucopolysaccharide polysulfate cream treatment...
March 2016: Plastic and Reconstructive Surgery
Susan Peters, Matthew J Page, Michel W Coppieters, Mark Ross, Venerina Johnston
BACKGROUND: Various rehabilitation treatments may be offered following carpal tunnel syndrome (CTS) surgery. The effectiveness of these interventions remains unclear. This is the first update of a review first published in 2013. OBJECTIVES: To review the effectiveness and safety of rehabilitation interventions following CTS surgery compared with no treatment, placebo, or another intervention. SEARCH METHODS: On 29 September 2015, we searched the Cochrane Neuromuscular Specialised Register, the Cochrane Register of Controlled Trials (CENTRAL), MEDLINE, EMBASE, CINAHL Plus, AMED, LILACS, and PsycINFO...
2016: Cochrane Database of Systematic Reviews
Julia Y Kang, Kimberly D Tran, Stuart R Seiff, William P Mack, Wendy W Lee
PURPOSE: The purpose of this study was to provide preliminary data on the potential effectiveness of the combination of topical Arnica montana and Rhododendron tomentosum (Ledum palustre) in reducing postoperative ecchymosis and edema in a select population of healthy volunteers after oculofacial surgery. METHODS: This retrospective review examined the postoperative course of healthy volunteers using topical Arnica and Ledum after undergoing common oculofacial procedures, including blepharoplasty, browpexy, and rhinoplasty, in the hands of 4 surgeons at tertiary referral centers from July 1, 2012 to December 31, 2012 using medical records review...
February 9, 2016: Ophthalmic Plastic and Reconstructive Surgery
Mary Morris, Janice Pellow, Elizabeth Margaret Solomon, Tebogo Tsele-Tebakang
CONTEXT: Osteoarthritis (OA) is a common cause of chronic low-back pain (CLBP) and can be managed with drug therapy and physiotherapy. Homeopathic remedies may assist managing OA; however, research that supports their effectiveness is limited. OBJECTIVES: The study aimed to investigate the efficacy of a homeopathic complex in combination with physiotherapy in treating CLBP due to OA. DESIGN: The study was a 6-wk, randomized, double-blind, placebo-controlled pilot...
January 2016: Alternative Therapies in Health and Medicine
Mariel de Barros, Luisa Mota da Silva, Thaise Boeing, Lincon Bordignon Somensi, Benhur Judah Cury, Ligia de Moura Burci, José Roberto Santin, Sérgio Faloni de Andrade, Franco Delle Monache, Valdir Cechinel-Filho
Solidago chilensis Meyenmost (Asteraceae), popularly known as "Brazilian arnica" or "arnica-do-campo," is widely used in the folk medicine to treat gastric disorders. Based on this, the gastroprotective activity of S. chilensis methanolic extract was investigated. Besides, a phytochemical study allowed isolation of two flavonoids (quercitrin and afzelin). The gastroprotective effects were investigated in acute gastric ulcer models, and the antisecretory activity was assessed in vivo and in vitro. The adhered mucus levels, reduced glutathione (GSH) content and myeloperoxidase (MPO) activity were quantified in ulcerated tissues...
April 2016: Naunyn-Schmiedeberg's Archives of Pharmacology
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