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Adrenaline and shock in neonates

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https://www.readbyqxmd.com/read/23128058/effects-of-terlipressin-on-pulmonary-artery-pressure-in-a-septic-cooled-infant-an-echocardiographic-assessment
#1
M Radicioni, S Troiani, P G Camerini
Experience with terlipressin (TP) in the neonatal field is scarce. We describe the effects of TP on pulmonary circulation, studied with echocardiography, in an asphyxiated septic cooled infant with pulmonary hypertension (PH) who developed catecholamine-resistant hypotension and exacerbation of PH shortly after the beginning of the rewarming. TP was added to norephinephine and adrenaline infusions at the dose of 0.02 mg kg(-1) every 6 h, because of refractory hypotension and oliguria. After 10 min, blood pressure dramatically and definitely increased, and urinary output was re-established after 60 min...
November 2012: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/22394653/neonates-presenting-with-severe-complications-of-frenotomy-a-case-series
#2
Peace I Opara, Nneka Gabriel-Job, Kingsley O Opara
INTRODUCTION: Tongue-tie or ankyloglossia is an anatomic variation in which the lingual frenulum is thick, short or tight. It may be asymptomatic, or present with complications like breast feeding difficulties or speech, dental and cosmetic problems. The treatment of this condition, where indicated, is frenotomy. This procedure usually has few or no complications. However, when it is done by untrained personnel, it may lead to life-threatening complications. This paper highlights complications that could arise from improper treatment of ankyloglossia...
2012: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/21048262/intravenous-adrenaline-for-shock-in-neonates
#3
Ruchi Rai, D K Singh
Dopamine and dobutamine have been widely used to treat shock with variable success in newborns. In this retrospective data analysis, we report on the use of adrenaline in 20 neonates with birth asphyxia and shock that was refractory to dopamine and dobutamine. We concluded that adrenaline is a safe and effective drug that can be used as an add-on therapy to dopamine and/or dobutamine in newborns with shock secondary to birth asphyxia.
September 2010: Indian Pediatrics
https://www.readbyqxmd.com/read/20960907/-a-case-of-anaphylactic-shock-induced-by-latex-during-cesarean-section
#4
Nahomi Ikeda, Yutaka Oda, Katsuaki Tanaka, Taketo Nakamura, Akira Asada
We report a 39-year-old woman who showed intraoperative anaphylactic shock during elective cesarean section in the 38th week of pregnancy. She underwent cesarean sections under general anesthesia at 33 years of age, and under spinal anesthesia at 37 years without any complication; other past history was unremarkable. Spinal anesthesia was performed with 0.5% hyperbaric bupivacaine 2.5 ml and analgesia level up to T2 was obtained 12 minutes later. The operation was uneventful at the birth of a neonate weighing 2700 g delivered with Apgar scores of 8 and 9 at 1 and 5 minutes, respectively...
October 2010: Masui. the Japanese Journal of Anesthesiology
https://www.readbyqxmd.com/read/20308763/intravenous-adrenaline-for-shock-in-neonates
#5
Ruchi Rai, D K Singh
Dopamine and dobutamine have been widely used to treat shock with variable success in newborns. In this retrospective data analysis, we report on the use of adrenaline in 20 neonates with birth asphyxia and shock that was refractory to dopamine and dobutamine. We concluded that adrenaline is a safe and effective drug that can be used as an add-on therapy to dopamine and/or dobutamine in newborns with shock secondary to birth asphyxia.
January 15, 2010: Indian Pediatrics
https://www.readbyqxmd.com/read/20094123/-paediatric-intensive-care
#6
Ulf Mostad, Sigurd Fasting
BACKGROUND: Child physiology and disease is not the same as in adults, which implies different challenges within intensive care. The aim of this review article is to shed light on special diagnostic and therapeutic problems in paediatric intensive care. MATERIAL AND METHODS: The review is based on literature identified through a non-systematic search in PubMed, and on the authors' own clinical experience. RESULTS: Common causes for admitting children to intensive care units are head injuries; septic shock and respiratory failure...
January 14, 2010: Tidsskrift for Den Norske Lægeforening: Tidsskrift for Praktisk Medicin, Ny Række
https://www.readbyqxmd.com/read/16640220/-european-resuscitation-council-guidelines-for-cardiopulmonary-resuscitation-in-2005
#7
Silvija Hunyadi-Anticević, Ingrid Bosan-Kilibarda, Zeljko Colak, Boris Filipović-Grcić, Ivan Gornik, Ines Lojna-Funtak, Zdravka Poljaković, Aleksandar Schnapp, Branka Tomljanović
ADULT BASIC LIFE SUPPORT: The ratio of compressions to ventilations is 30:2 for all adult victims of cardiac arrest. AUTOMATED EXTERNAL DEFIBRILLATION: A single defibrillatory shock is delivered, immediately followed by two minutes of uninterrupted CPR. ADULT ADVANCED LIFE SUPPORT: In out-of-hospital cardiac arrest attended, but unwitnessed, by healthcare professionals equipped with manual defibrillators, give CPR for 2 minutes before defibrillation. The recommended initial energy for biphasic defibrillators is 150-200 J, for second and subsequent shocks is 150-360 J...
January 2006: Lijec̆nic̆ki Vjesnik
https://www.readbyqxmd.com/read/9121076/-therapy-refractory-arterial-hypotension-after-heart-operation
#8
K Frenzel, G Burda, G Fürst, J Golej, M Hermon, G Trittenwein, A Pollak
Adrenalin insufficiency associated with adrenal hemorrhage, is a rare complication after cardiac surgery in neonates. A boy suffering from transposition of the great arteries, who had an arterial switch-operation on day three of his life, acquired a bilateral adrenal hemorrhage. Clinically the situation resembled a septic shock. Despite large doses of catecholamines, he continued to have severe arterial hypotension, anuria, and kyperkalemia. The clinical condition did not change, although sepsis specific therapy was initiated...
January 1997: Klinische Pädiatrie
https://www.readbyqxmd.com/read/8403246/desensitization-of-rat-cardiomyocyte-adenylyl-cyclase-stimulation-by-plasma-of-noradrenaline-treated-patients-with-septic-shock
#9
C Reithmann, S Hallström, G Pilz, T Kapsner, G Schlag, K Werdan
The purpose of this study was to test the possibility that the mechanisms of catecholamine-induced desensitization of cardiac beta-adrenoceptor stimulation are modified in septic shock. Exposure of neonatal rat cardiomyocytes for 48 hr to plasma of noradrenaline-treated patients with septic shock led to a down-regulation of beta-adrenoceptors by 35%, an increase in the level of inhibitory G protein alpha-subunits by 60%, and a decrease in isoproterenol-stimulated adenylyl cyclase activity by 50% in membranes prepared from the rat cardiomyocytes...
September 1993: Circulatory Shock
https://www.readbyqxmd.com/read/1841948/capsaicin-sensitive-sensory-neurons-are-involved-in-the-plasma-catecholamine-response-of-rats-to-selective-stressors
#10
X F Zhou, B G Livett
1. The effect of capsaicin pre-treatment on adrenal catecholamine (CA) secretion in response to stress is controversial. In earlier experiments performed under pentobarbitone anaesthesia, the release of CA in response to stress was complicated by the effects of the barbiturate anaesthesia. 2. In the present study we have used conscious freely moving rats with indwelling cannulae to study the effect of neonatal capsaicin pre-treatment on the plasma CA response to different types of stressors (swimming stress, hypovolaemic stress, immobilization stress and cold stress)...
February 1991: Journal of Physiology
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