keyword
https://read.qxmd.com/read/38537225/a-randomized-noninferiority-trial-to-compare-enteral-to-parenteral-phosphate-replacement-on-biochemistry-waste-and-environmental-impact-and-healthcare-cost-in-critically-ill-patients-with-mild-to-moderate-hypophosphatemia
#1
JOURNAL ARTICLE
Chinh D Nguyen, Haustine P Panganiban, Timothy Fazio, Amalia Karahalios, Melissa Akravs, Christopher M MacIsaac, Thomas Rechnitzer, Lucy Arno, An Tran-Duy, Scott McAlister, Yasmine Ali Abdelhamid, Adam M Deane
OBJECTIVES: Hypophosphatemia occurs frequently. Enteral, rather than IV, phosphate replacement may reduce fluid replacement, cost, and waste. DESIGN: Prospective, randomized, parallel group, noninferiority clinical trial. SETTING: Single center, 42-bed state trauma, medical and surgical ICUs, from April 20, 2022, to July 1, 2022. PATIENTS: Patients with serum phosphate concentration between 0.3 and 0.75 mmol/L. INTERVENTIONS: We randomized patients to either enteral or IV phosphate replacement using electronic medical record-embedded program...
March 25, 2024: Critical Care Medicine
https://read.qxmd.com/read/38537124/genetically-identifying-the-thrombo-embolic-in-cteph
#2
JOURNAL ARTICLE
Christina A Eichstaedt
No abstract text is available yet for this article.
March 27, 2024: American Journal of Respiratory and Critical Care Medicine
https://read.qxmd.com/read/38537116/featured-articles-for-cme-credit-april-2024
#3
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
April 1, 2024: Journal of Trauma and Acute Care Surgery
https://read.qxmd.com/read/38536762/the-impact-of-musculoskeletal-ill-health-on-quality-of-life-and-function-after-critical-care-a-multicentre-prospective-cohort-study
#4
JOURNAL ARTICLE
O D Gustafson, E B King, M M Schlussel, A Arnold, C Wade, P S Nicol, M J Rowland, H Dawes, M A Williams
Physical disability is a common component of post-intensive care syndrome, but the importance of musculoskeletal health in this population is currently unknown. We aimed to determine the musculoskeletal health state of intensive care unit survivors and assess its relationship with health-related quality of life; employment; and psychological and physical function. We conducted a multicentre prospective cohort study of adults admitted to intensive care for > 48 h without musculoskeletal trauma or neurological insult...
March 27, 2024: Anaesthesia
https://read.qxmd.com/read/38536623/gut-barrier-dysfunction-and-the-risk-of-icu-acquired-bacteremia-a-case-control-study
#5
JOURNAL ARTICLE
Meri R J Varkila, Diana M Verboom, Lennie P G Derde, Tom van der Poll, Marc J M Bonten, Olaf L Cremer
BACKGROUND: Impaired intestinal barrier function can enable passage of enteric microorganisms into the bloodstream and lead to nosocomial bloodstream infections during critical illness. We aimed to determine the relative importance of gut translocation as a source for ICU-acquired enterococcal bacteremia of unknown origin. METHODS: We conducted a nested case-control study in two mixed medical-surgical tertiary ICUs in the Netherlands among patients enrolled between 2011 and 2018...
March 27, 2024: Annals of Intensive Care
https://read.qxmd.com/read/38536545/early-sevoflurane-sedation-in-severe-covid-19-related-lung-injury-patients-a-pilot-randomized-controlled-trial
#6
JOURNAL ARTICLE
Beatrice Beck-Schimmer, Erik Schadde, Urs Pietsch, Miodrag Filipovic, Seraina Dübendorfer-Dalbert, Patricia Fodor, Tobias Hübner, Reto Schuepbach, Peter Steiger, Sascha David, Bernard D Krüger, Thomas A Neff, Martin Schläpfer
BACKGROUND: This study aimed to assess a potential organ protective effect of volatile sedation in a scenario of severe inflammation with an early cytokine storm (in particular IL-6 elevation) in patients suffering from COVID-19-related lung injury with invasive mechanical ventilation and sedation. METHODS: This is a small-scale pilot multicenter randomized controlled trial from four tertiary hospitals in Switzerland, conducted between April 2020 and May 2021. 60 patients requiring mechanical ventilation due to severe COVID-19-related lung injury were included and randomized to 48-hour sedation with sevoflurane vs...
March 27, 2024: Annals of Intensive Care
https://read.qxmd.com/read/38536534/serial-daily-lactate-levels-association-with-30-day-outcome-in-cardiogenic-shock-patients-treated-with-va-ecmo-a-post-hoc-analysis-of-the-hypo-ecmo-study
#7
JOURNAL ARTICLE
Bruno Levy, Nicolas Girerd, Guillaume Baudry, Kevin Duarte, Samuel Cuau, Jan Bakker, Antoine Kimmoun
BACKGROUND: Reliable predictors of outcomes in venoarterial extracorporeal membrane oxygenation (VA-ECMO) therapy are limited. While elevated lactate levels over time have been linked to outcomes in cardiogenic shock (CS), their significance in VA-ECMO-treated patients remains inconclusive. METHODS: We conducted a post hoc analysis of data from the HYPO-ECMO trial, which compared normothermia to moderate hypothermia in CS patients supported by VA-ECMO. We examined daily lactate levels collected over a week to assess their correlation with 30-day mortality...
March 27, 2024: Annals of Intensive Care
https://read.qxmd.com/read/38536469/correction-contrast-enhanced-ultrasound-ceus-in-the-follow-up-of-abdominal-solid-organ-trauma-an-international-survey-prior-to-the-psean-study
#8
Giuliano Santolamazza, Francesco Virdis, Fikri Abu-Zidan, Stefano Piero Bernardo Cioffi, Elisa Reitano, Michele Altomare, Roberto Bini, Andrea Spota, Mauro Podda, Jayant Kumar, Osvaldo Chiara, Stefania Cimbanassi
No abstract text is available yet for this article.
March 27, 2024: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://read.qxmd.com/read/38536468/traumatic-rhabdomyolysis-rare-but-morbid-potentially-lethal-and-inconsistently-monitored
#9
JOURNAL ARTICLE
Thomas Giles, Kate King, Simone Meakes, Natasha Weaver, Zsolt J Balogh
PURPOSE: Although traumatic rhabdomyolysis (TR) is shown to be associated with acute kidney injury (AKI), there are no large prospective epidemiological studies, interventional trials, official guidelines outlining the appropriate investigation, monitoring, and treatment on this poorly understood condition. We aimed to establish the contemporary epidemiology and describe current practices for TR to power future higher quality studies. We hypothesised that investigation and monitoring occur in an ad hoc fashion...
March 27, 2024: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://read.qxmd.com/read/38536423/-optinofa-intelligent-assistance-service-for-structured-assessment-in-the-emergency-department
#10
JOURNAL ARTICLE
Elisabeth Nyoungui, Marina V Karg, Marc Wieckenberg, Katrin Esslinger, Michael Schmucker, Andreas Reiswich, Kai L Antweiler, Tim Friede, Martin Haag, Harald Dormann, Sabine Blaschke
BACKGROUND: Case numbers in central emergency departments (EDs) have risen during the past decade in Germany, leading to recurrent overcrowding, increased risks in emergency care, and elevated costs. Particularly the fraction of outpatient emergency treatments has increased disproportionately. Within the framework of the Optimization of emergency care by structured triage with intelligent assistant service (OPTINOFA, Förderkennzeichen [FKZ] 01NVF17035) project, an intelligent assistance service was developed...
March 27, 2024: Medizinische Klinik, Intensivmedizin und Notfallmedizin
https://read.qxmd.com/read/38536422/-in-memory-of-prof-dr-med-tobias-welte
#11
EDITORIAL
Michael Buerke, Paul Herrmann
No abstract text is available yet for this article.
March 27, 2024: Medizinische Klinik, Intensivmedizin und Notfallmedizin
https://read.qxmd.com/read/38536421/assessing-lung-recruitability-does-it-help-with-peep-settings
#12
EDITORIAL
Luciano Gattinoni, Francesca Collino, Luigi Camporota
No abstract text is available yet for this article.
March 27, 2024: Intensive Care Medicine
https://read.qxmd.com/read/38536165/high-dimensional-mass-cytometry-reveals-emphysema-associated-changes-in-the-pulmonary-immune-system
#13
JOURNAL ARTICLE
Li Jia, Na Li, Tamim R M Abdelaal, Nannan Guo, Marieke E IJsselstein, Vincent van Unen, Ciska Lindelauf, Qinyue Jiang, Yanling Xiao, M Fernanda Pascutti, Pieter S Hiemstra, Frits Koning, Jan Stolk, P Padmini S J Khedoe
RATIONALE: Chronic inflammation plays an important role in alveolar tissue damage in emphysema, but the underlying immune alterations and cellular interactions are incompletely understood. OBJECTIVE: To explore disease-specific pulmonary immune cell alterations and cellular interactions in emphysema. METHODS: We used single-cell mass cytometry to compare the immune compartment in alveolar tissue from 15 patients with severe emphysema and 5 controls...
March 27, 2024: American Journal of Respiratory and Critical Care Medicine
https://read.qxmd.com/read/38536158/definitions-of-dysbiosis-in-clad-and-high-bacterial-biomass
#14
JOURNAL ARTICLE
John McGinniss
No abstract text is available yet for this article.
March 27, 2024: American Journal of Respiratory and Critical Care Medicine
https://read.qxmd.com/read/38536110/epidemiology-and-prognostic-significance-of-cough-in-fibrotic-interstitial-lung-disease
#15
JOURNAL ARTICLE
Yet H Khor, Kerri A Johannson, Veronica Marcoux, Jolene H Fisher, Deborah Assayag, Helene Manganas, Nasreen Khalil, Martin Kolb, Christopher J Ryerson
Rationale: Cough is a key symptom in patients with fibrotic interstitial lung disease (ILD). Objective: This study evaluated the prevalence, longitudinal change, associations, and prognostic significance of cough severity in patients with fibrotic ILD. Methods: We included consecutive patients with idiopathic pulmonary fibrosis (IPF) and non-IPF fibrotic ILD who completed the 100mm-Cough Severity Visual Analog Scale (VAS) from the prospective multi-center Canadian Registry for Pulmonary Fibrosis. Baseline cough severity and associations with patient demographics and clinical factors were determined...
March 27, 2024: American Journal of Respiratory and Critical Care Medicine
https://read.qxmd.com/read/38536108/telehealth-pulmonary-rehabilitation-a-call-for-minimum-standards
#16
JOURNAL ARTICLE
Surya P Bhatt, Richard Casaburi, Christopher L Mosher, Carolyn L Rochester, Chris Garvey
No abstract text is available yet for this article.
March 27, 2024: American Journal of Respiratory and Critical Care Medicine
https://read.qxmd.com/read/38535489/pragmatic-approach-to-in-situ-simulation-to-identify-latent-safety-threats-before-moving-to-a-newly-built-icu
#17
JOURNAL ARTICLE
Aarti Sarwal, Nicholas A Morris, Janet Crumpler, Terri Gordon, Ian Saunders, James E Johnson, Jeff E Carter
OBJECTIVES: Transitions to new care environments may have unexpected consequences that threaten patient safety. We undertook a quality improvement project using in situ simulation to learn the new patient care environment and expose latent safety threats before transitioning patients to a newly built adult ICU. DESIGN: Descriptive review of a patient safety initiative. SETTING: A newly built 24-bed neurocritical care unit at a tertiary care academic medical center...
March 27, 2024: Critical Care Medicine
https://read.qxmd.com/read/38535090/machine-learning-identifies-higher-survival-profile-in-extracorporeal-cardiopulmonary-resuscitation
#18
JOURNAL ARTICLE
Ruben Crespo-Diaz, Julian Wolfson, Demetris Yannopoulos, Jason A Bartos
OBJECTIVES: Extracorporeal cardiopulmonary resuscitation (ECPR) has been shown to improve neurologically favorable survival in patients with refractory out-of-hospital cardiac arrest (OHCA) caused by shockable rhythms. Further refinement of patient selection is needed to focus this resource-intensive therapy on those patients likely to benefit. This study sought to create a selection model using machine learning (ML) tools for refractory cardiac arrest patients undergoing ECPR. DESIGN: Retrospective cohort study...
March 27, 2024: Critical Care Medicine
https://read.qxmd.com/read/38535027/detection-of-acute-brain-injury-in-intensive-care-unit-patients-on-ecmo-support-using-ultra-low-field-portable-mri-a-retrospective-analysis-compared-to-head-ct
#19
JOURNAL ARTICLE
Sung-Min Cho, Shivalika Khanduja, Jiah Kim, Jin Kook Kang, Jessica Briscoe, Lori R Arlinghaus, Kha Dinh, Bo Soo Kim, Haris I Sair, Audrey-Carelle N Wandji, Elena Moreno, Glenda Torres, Jose Gavito-Higuera, Huimahn A Choi, John Pitts, Aaron M Gusdon, Glenn J Whitman
Early detection of acute brain injury (ABI) is critical to intensive care unit (ICU) patient management and intervention to decrease major complications. Head CT (HCT) is the standard of care for the assessment of ABI in ICU patients; however, it has limited sensitivity compared to MRI. We retrospectively compared the ability of ultra-low-field portable MR (ULF-pMR) and head HCT, acquired within 24 h of each other, to detect ABI in ICU patients supported on extracorporeal membrane oxygenation (ECMO). A total of 17 adult patients (median age 55 years; 47% male) were included in the analysis...
March 13, 2024: Diagnostics
https://read.qxmd.com/read/38535014/ultrasound-during-advanced-life-support-help-or-harm
#20
JOURNAL ARTICLE
Adrian Goudie, Michael Blaivas, Rudolf Horn, Wan-Ching Lien, Guido Michels, Daniel Wastl, Christoph Frank Dietrich
Ultrasound is used in cardiopulmonary resuscitation (CPR) and advanced life support (ALS). However, there is divergence between the recommendations of many emergency and critical care societies who support its use and the recommendations of many international resuscitation organizations who either recommend against its use or recommend it only in limited circumstances. Ultrasound offers potential benefits of detecting reversable causes of cardiac arrest, allowing specific interventions. However, it also risks interfering with ALS protocols and increasing unhelpful interventions...
March 11, 2024: Diagnostics
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