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year book of pathology

M Jungheim, M Ptok
BACKGROUND: To transport a bolus from the mouth into the stomach, regular contraction of the pharyngeal muscles and a coordinated function of the upper esophageal sphincter (UES) are necessary. The muscle contraction generates intraluminal pressure, which pushes the bolus continuously forward. In contrast to imaging studies, manometric methods enable assessment of intraluminal pressure buildup and the function of the muscles involved. These methods were initially established for the esophagus and have been used increasingly in the pharynx for 7-8 years...
May 19, 2017: HNO
Nora Katabi, James S Lewis
The World Health Organization (WHO) 2017 Classification of Head and Neck Tumors ("Blue Book") will now include a new chapter on tumors and tumor-like lesions of the neck and lymph nodes, which was not included in the previous edition. Tumors and tumor-like lesions, including a variety of cysts and metastases, can arise in any component in the neck, including soft tissue, lymph nodes, and developmental remnants. The pathology and clinical features of metastatic carcinoma of unknown primary in the head and neck has changed dramatically in the last several years...
March 2017: Head and Neck Pathology
Bogumił Lewandowski, Robert Brodowski, Paweł Pakla, Aleksander Makara, Wojciech Stopyra, Bartek Startek
INTRODUCTION: Mucoceles are benign lesions associated with the pathology of the oral mucosa of minor salivary glands. Two types of cysts are distinguished depending on their pathogenesis. Most often they occur as a result of mechanical trauma and mucus extravasation into tissues or obstruction of the gland ducts. AIM: The aim of the study was to present our own experiences regarding mucoceles of minor salivary glands in the oral cavity taking into account how frequently the individual types of cysts occur in children...
2016: Developmental Period Medicine
Sarangarajan Ranganathan
The study of Histiocytic lesions has been a passion of Pepper Dehner over the years. He has contributed several case series and reviews on various categories of these diseases for over 4 decades, with his earliest articles in the 1970s. He has written on all aspects of the disease including seminal articles on Langerhans cell histiocytosis (LCH) and their prognostic features, his experiences with regressing atypical histiocytosis, his encounters with malignant histiocytosis, and classic articles on juvenile xanthogranuloma...
November 2016: Seminars in Diagnostic Pathology
Rommy von Bernhardi, Jaime Eugenín-von Bernhardi, Betsi Flores, Jaime Eugenín León
Today, there is enormous progress in understanding the function of glial cells, including astroglia, oligodendroglia, Schwann cells, and microglia. Around 150 years ago, glia were viewed as a glue among neurons. During the course of the twentieth century, microglia were discovered and neuroscientists' views evolved toward considering glia only as auxiliary cells of neurons. However, over the last two to three decades, glial cells' importance has been reconsidered because of the evidence on their involvement in defining central nervous system architecture, brain metabolism, the survival of neurons, development and modulation of synaptic transmission, propagation of nerve impulses, and many other physiological functions...
2016: Advances in Experimental Medicine and Biology
Emrah Celtikci, A Memduh Kaymaz, Gulsah Akgul, Burak Karaaslan, O Hakan Emmez, Alp Borcek
AIM: Meningioma literature has many large surgical case series which have been references of text books and neurosurgical practice. Many of those series were investigated before stereotactic radiosurgery (SRS) practice were not so often or were in terms of WHO 2000 classification. In this study we aimed an update to the current literature by using WHO 2007 classification. MATERIAL AND METHODS: 488 intracranial meningioma patients underwent open surgery. All pathological specimens re-evaluated in terms of WHO 2007 classification...
August 5, 2016: Turkish Neurosurgery
Wojciech Krajewski, Mateusz Dzięgała, Anna Kołodziej, Janusz Dembowski, Romuald Zdrojowy
INTRODUCTION: Vitamin D controls calcium and phosphate homeostasis. Additionally, it has been proven that vitamin D is an important modulator of cellular differentiation and proliferation in a number of normal and malignant cells. Vitamin D can regulate proliferation, apoptosis, and cell adhesion at the tumor cell level. It also modifies tumor angiogenesis, invasion, and metastasis and also decreases oxidative DNA damage. MATERIAL AND METHODS: The Medline and Web of Science databases were searched without time limit on October 2015 using the terms 'vitamin D' in conjunction with 'kidney cancer', 'bladder cancer', 'prostate cancer', and 'testis cancer'...
2016: Central European Journal of Urology
T O Babatunde, J O Ogunbiyi
BACKGROUND: Biliary tract carcinomas are uncommon but highly fatal malignancies. Most patients in our environment are diagnosed late and are not candidates for curative resection. OBJECTIVE: To determine the pattern and risk factors of biliary tract carcinoma in Ibadan. METHODOLOGY: This was a retrospective study of histologically confirmed cases of biliary tract carcinoma diagnosed at the University College Hospital, Ibadan between January 1971 and December 20 10...
December 2015: African Journal of Medicine and Medical Sciences
Xuezhi Zhang, Thierry Soldati
Since the discovery of the formation of DNA-based extracellular traps (ETs) by neutrophils as an innate immune defense mechanism (1), hundreds of articles describe the involvement of ETs in physiological and pathological human and animal conditions [reviewed in Ref. (2), and the previous Frontiers Research Topic on NETosis:]. Interestingly, a few reports reveal that ETs can be formed by immune cells of more ancient organisms, as far back as the common ancestor of vertebrates and invertebrates (3)...
2016: Frontiers in Immunology
Tessa Fayers, Peter J Dolman
PURPOSE: To assess whether the use of silicone lacrimal stents affects the long-term success of endonasal dacryocystorhinostomy (EN-DCR). DESIGN: Prospective, randomized, controlled, interventional trial. PARTICIPANTS: The subjects were adult patients older than 16 years undergoing primary EN-DCR for nasolacrimal duct obstruction who gave fully informed consent and who had no lid malpositions or canalicular pathology. In cases with bilateral surgery, only the right eyes were studied...
October 2016: Ophthalmology
Nicole Hubner, Jacob Charles Langer, Sari Kives, Lisa Mary Allen
STUDY OBJECTIVE: The aim of this study was to document the change in ovarian conservation rate after ovarian torsion as a result of continuous quality improvement (CQI) measures, and to determine factors that contribute to this outcome. DESIGN: A retrospective, uncontrolled before-and-after study. SETTING: An academic children's hospital. PARTICIPANTS: Female adolescents younger than 18 years with surgically confirmed ovarian torsion from April 1, 1988 to October 15, 2013; excluding cases from 2003 (intervention period)...
February 2017: Journal of Pediatric and Adolescent Gynecology
Rakan M AlDarrab, Hamad S AlAkrash, Sultan S AlKhateeb, Nasser M AlBqami
A 44-year-old female presented to the urology clinic with flank pain and tenderness. After full assessment, the patient was booked for surgery for partial nephrectomy and the patient was diagnosed with renal cell carcinoma (RCC) chromophob type. Six months later, the patient came back for follow-up; a mass was detected on the same kidney. Radical nephrectomy was performed to excise what is thought to be a recurrence of RCC and the tissues were sent to pathology. The postoperative pathology report confirmed the presence of xanthogranulomatous pyelonephritis rather than RCC recurrence...
October 2015: Urology Annals
Anna Lena Ress, Samantha Perakis, Martin Pichler
Colorectal cancer (CRC) is one of the most common types of human cancer with high cancer-related morbidity and mortality rates. The development and clinical validation of novel therapeutic avenues have improved the clinical outcome, but metastatic CRC still remains an incurable disease in most cases. The interest in discovering novel pathophysiological drivers in CRC is intensively ongoing and the search for novel biomarkers for early diagnosis, for patient's stratification for prognostic purposes or for predicting treatment response are warranted...
2015: Advances in Experimental Medicine and Biology
Seyed Mahmoud Tabatabaei, Nastaran Sabetkish, Seyed Mohammad Ali Tabatabaei
Despite the fact that ophthalmology is one of the foremost branches of medicine, conceptualization of the structure and function of the eye barely advanced in ancient Western civilizations. At the early recovery of Persian civilization (9(th) century AD) after the extinction of the Sassanid Empire (7(th) century AD), translations of Greek medical textbooks played an important role in the development of medicine and the emergence of great Persian physicians such as Rhazes, Avicenna and others. Rhazes was a leading Persian physician whose medical teachings have as yet not been thoroughly explored...
2014: Journal of Medical Ethics and History of Medicine
Laure Léger, Boris Gojanovic, Nicole Sekarski, Erik J Meijboom, Yvan Mivelaz
Sudden cardiac death (SCD) affects 2/100,000 young, active athletes per year of which 40% are less than 18 years old. In 2004, the International Olympic Committee accepted the Lausanne Recommendations, including a 12-lead electrocardiogram (ECG), as a pre-participation screening tool for adult Olympic athletes. The debate on extending those recommendations to the pediatric population has recently begun. The aims of our study were to highlight the characteristics of the young athlete ECG, phenotypical manifestations of SCD-related disease in children, and challenges of implanting ECG screening in athletic children...
January 2016: Pediatric Cardiology
Elan D Louis
Morgagni's 1761 publication of De sedibus et causis morborum (i.e., of the Seats and Causes of Diseases) represented a paradigmatic moment in the history of medicine. The book ushered in a new way of conceptualizing human disease, shattering old dogma, and linking constellations of symptoms and signs (i.e., clinical disease) with anatomic pathology in specific organs (i.e., organ disease). This was the anatomical-clinical method, and it attempted to unveil "the seat" of each disease in a specific organ. Essential tremor (ET) is among the most common neurological diseases...
2016: Cerebellum
Jane Yelland, Elisha Riggs, Josef Szwarc, Sue Casey, Philippa Duell-Piening, Donna Chesters, Sayed Wahidi, Fatema Fouladi, Stephanie Brown
INTRODUCTION: Difficulties associated with communication are thought to contribute to adverse perinatal outcomes experienced by refugee background women living in developed countries. This study explored Afghan women and men's experience of language support during pregnancy, labour and birth, and health professionals' experiences of communicating with clients of refugee background with low English proficiency. METHODS: Interviews were conducted with (1) Afghan women and men in the first year after having a baby in Australia, by multilingual, bicultural researchers and (2) midwives and medical practitioners providing care to families of refugee background...
April 2016: BMJ Quality & Safety
Ivica Mladenović, Goran Lažetić, Dušica Lečić-Toševski, Ivan Dimitrijević
Pathological gambling was classified under impulse control disorders within the International Classification of Diseases (ICD-10) (WHO 1992), but the most recent Diagnostic and Statistical Manual, 5th edition (DSM-V), (APA 2013), has recognized pathological gambling as a first disorder within a new diagnostic category of behavioral addictions - Gambling disorder. Pathological gambling is a disorder in progression, and we hope that our experience in the treatment of pathological gambling in the Daily Hospital for Addictions at The Institute of Mental Health, through the original "Integrative - systemic model" would be of use to colleagues, dealing with this pathology...
March 2015: Psychiatria Danubina
James Kennaway
The relationship between music and medicine is generally understood in the benign context of music therapy, but, as this chapter shows, there is a long parallel history of medical theories that suggest that music can cause real physical and mental illness. During the seventeenth and eighteenth centuries, the idea of music as an expression of universal harmony was challenged by a more mechanistic model of nervous stimulation. By the 1790s, there was a substantial discourse on the dangers of musical overstimulation to health in medicine, literature, and etiquette books...
2015: Progress in Brain Research
Barthélémy Tandu-Umba, Muela Andy Mbangama, Kitenge Marc Brunel Kamongola, Armel Georges Kamgang Tchawou, Mawamfumu Perthus Kivuidi, Sam Kasonga Munene, Irène Kambashi Meke, Oscar Kapuku Kabasele, Bituemi Jackson Kondoli, Kibundila Rolly Kikuni, Simon Kasikila Kuzungu
OBJECTIVE: To determine relationships between pre-pregnancy risk factors at first antenatal visit booking and pregnancy outcomes. STUDY DESIGN: This was a multicenter, cross-sectional study involving women admitted for singleton delivery from July 1 until October 31 (3 months), 2013, at nine major maternity clinics in Kinshasa, Democratic Republic of Congo. All women were checked for hereditary, community, and personal medical/surgical risk situations and mother/infant problems in previous pregnancies...
2014: International Journal of Women's Health
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