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https://www.readbyqxmd.com/read/29134296/p300-based-acuity-estimation-in-imitated-amblyopia
#1
Marvin L Beusterien, Sven P Heinrich
PURPOSE: A frequent approach to estimating visual acuity objectively is the recording of visual evoked potentials (VEPs) to patterns of different coarseness. This, however, overestimates acuity in patients with fragmented and distorted vision such as in amblyopia. This is likely due to VEP-based techniques using checkerboard or grating stimuli. We hypothesized that no overestimation would occur when the event-related potential P300 in response to optotype stimuli is used for acuity estimation...
November 13, 2017: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/29134137/pattern-electroretinography-and-visual-evoked-potentials-provide-clinical-evidence-of-cns-modulation-of-high-and-low-contrast-vep-latency-in-glaucoma
#2
William E Sponsel, Susan L Johnson, Rick Trevino, Alberto Gonzalez, Sylvia L Groth, Carolyn Majcher, Diane C Fulton, Matthew A Reilly
Purpose: Both pattern electroretinography (PERG) and visual evoked potentials (VEP) can be performed using low- (15%; Lc) and high- (85%; Hc) contrast gratings that may preferentially stimulate the magno- and parvocellular pathways. We observed that among glaucomatous patients showing only one VEP latency deficit per eye, there appeared to be a very strong tendency for an Hc delay in one eye and an Lc delay in the other. Methods: Diopsys NOVA-LX system was used to measure VEP Hc and Lc latency among a clinical glaucoma population to find all individuals with either a single Hc or Lc latency abnormality in each eye (group 1), or with greater than 0 and less than 4 Hc or Lc VEP latency abnormalities in the two eyes (group 2) to determine whether a significant inverse correlation existed for these values in either group...
2017: Translational Vision Science & Technology
https://www.readbyqxmd.com/read/29125983/functional-differences-between-healthy-and-diabetic-endothelial-cells-on-topographical-cues
#3
Marie F A Cutiongco, Bryan M X Chua, Dawn J H Neo, Muhammad Rizwan, Evelyn K F Yim
The endothelial lining of blood vessels is severely affected in type II diabetes. Yet, there is still a paucity on the use of diabetic endothelial cells for study and assessment of implantable devices targeting vascular disease. This critically impairs our ability to determine appropriate topographical cues to be included in implantable devices that can be used to maintain or improve endothelial cell function in vivo. Here, the functional responses of healthy and diabetic human coronary arterial endothelial cells were studied and observed to differ depending on topography...
October 25, 2017: Biomaterials
https://www.readbyqxmd.com/read/29124460/medical-egg-freezing-the-importance-of-a-patient-centered-approach-to-fertility-preservation
#4
Marcia C Inhorn, Daphna Birenbaum-Carmeli, Lynn M Westphal, Joseph Doyle, Norbert Gleicher, Dror Meirow, Hila Raanani, Martha Dirnfeld, Pasquale Patrizio
PURPOSE: This binational qualitative study of medical egg freezing (MEF) examined women's motivations and experiences, including their perceived needs for patient-centered care in the midst of fertility- and life-threatening diagnoses. METHODS: Forty-five women who had undertaken MEF were interviewed in the USA (33 women) and in Israel (12 women) between June 2014 and August 2016. Interviews lasted approximately 1 h and were conducted by two senior medical anthropologists, one in each country...
November 9, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/29120714/functional-magnetic-resonance-imaging-to-assess-neuroadaptation-to-multifocal-intraocular-lenses
#5
Andreia M Rosa, Ângela C Miranda, Miguel M Patrício, Colm McAlinden, Fátima L Silva, Miguel Castelo-Branco, Joaquim N Murta
PURPOSE: To evaluate the use of functional magnetic resonance imaging (MRI) to assess neuroadaptation to multifocal intraocular lenses (IOLs). SETTING: Faculty of Medicine, University of Coimbra, Coimbra, Portugal. DESIGN: Prospective case study. METHODS: Patients with bilateral diffractive IOL implantation after cataract surgery had functional MRI at postoperative intervals of 3 weeks and 6 months. A nonintervention control group was included as proof of concept...
October 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/29110946/assessment-of-the-electronic-retinal-implant-alpha-ams-in-restoring-vision-to-blind-patients-with-end-stage-retinitis-pigmentosa
#6
Thomas L Edwards, Charles L Cottriall, Kanmin Xue, Matthew P Simunovic, James D Ramsden, Eberhart Zrenner, Robert E MacLaren
PURPOSE: To report the initial efficacy results of the Retina Implant Alpha AMS (Retina Implant AG, Reutlingen, Germany) for partial restoration of vision in end-stage retinitis pigmentosa (RP). DESIGN: Prospective, single-arm, investigator-sponsored interventional clinical trial. Within-participant control comprising residual vision with the retinal implant switched ON versus OFF in the implanted eye. PARTICIPANTS: The Retina Implant Alpha AMS was implanted into the worse-seeing eye of 6 participants with end-stage RP and no useful perception of light vision...
October 27, 2017: Ophthalmology
https://www.readbyqxmd.com/read/29060024/robust-tracking-of-dexterous-continuum-robots-fusing-fbg-shape-sensing-and-stereo-vision
#7
Rumei Zhang, Hao Liu, Jianda Han
Robust and efficient tracking of continuum robots is important for improving patient safety during space-confined minimally invasive surgery, however, it has been a particularly challenging task for researchers. In this paper, we present a novel tracking scheme by fusing fiber Bragg grating (FBG) shape sensing and stereo vision to estimate the position of continuum robots. Previous visual tracking easily suffers from the lack of robustness and leads to failure, while the FBG shape sensor can only reconstruct the local shape with integral cumulative error...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28987906/visually-evoked-responses-from-the-blind-field-of-hemianopic-patients
#8
Javier Sanchez-Lopez, Caterina A Pedersini, Francesco Di Russo, Nicolò Cardobi, Cristina Fonte, Valentina Varalta, Massimo Prior, Nicola Smania, Silvia Savazzi, Carlo A Marzi
Hemianopia is a visual field defect characterized by decreased vision or blindness in the contralesional visual field of both eyes. The presence of well documented above-chance unconscious behavioural responses to visual stimuli presented to the blind hemifield (blindsight) has stimulated a great deal of research on the neural basis of this important phenomenon. The present study is concerned with electrophysiological responses from the blind field. Since previous studies found that transient Visual Evoked Potentials (VEPs) are not entirely suitable for this purpose here we propose to use Steady-State VEPs (SSVEPs)...
October 5, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/28979077/developing-an-integrated-treatment-pathway-for-a-post-coronary-artery-bypass-grating-cabg-geriatric-patient-with-comorbid-hypertension-and-type-1-diabetes-mellitus-for-treating-acute-hypoglycemia-and-electrolyte-imbalance
#9
Atta Abbas Naqvi, Amna Shah, Rizwan Ahmad, Niyaz Ahmad
INTRODUCTION: The ailments afflicting the elderly population is a well-defined specialty of medicine. It calls for an immaculately designed health-care plan to treat diseases in geriatrics. For chronic illnesses such as diabetes mellitus (DM), coronary heart disease, and hypertension (HTN), they require proper management throughout the rest of patient's life. An integrated treatment pathway helps in treatment decision-making and improving standards of health care for the patient. CASE PRESENTATION: This case describes an exclusive clinical pharmacist-driven designing of an integrated treatment pathway for a post-coronary artery bypass grafting (CABG) geriatric male patient with DM type I and HTN for the treatment of hypoglycemia and electrolyte imbalance...
July 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/28972542/the-ohio-contrast-cards-visual-performance-in-a-pediatric-low-vision-site
#10
Gregory R Hopkins, Bradley E Dougherty, Angela M Brown
SIGNIFICANCE: This report describes the first clinical use of the Ohio Contrast Cards, a new test that measures the maximum spatial contrast sensitivity of low-vision patients who cannot recognize and identify optotypes and for whom the spatial frequency of maximum contrast sensitivity is unknown. PURPOSE: To compare measurements of the Ohio Contrast Cards to measurements of three other vision tests and a vision-related quality-of-life questionnaire obtained on partially sighted students at Ohio State School for the Blind...
October 2017: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/28963615/brain-networking-analysis-in-migraine-with-and-without-aura
#11
Marina de Tommaso, Gabriele Trotta, Eleonora Vecchio, Katia Ricci, R Siugzdaite, Sebastiano Stramaglia
BACKGROUND: To apply effective connectivity by means of nonlinear Granger Causality (GC) and brain networking analysis to basal EEG and under visual stimulation by checkerboard gratings with 0.5 and 2.0 cpd as spatial frequency in migraine with aura (MA) and without aura (MO), and to compare these findings with Blood Oxygen Level Dependent (BOLD) signal changes. METHODS: Nineteen asymptomatic MA and MO patients and 11 age and sex matched controls (C) were recorded by 65 EEG channels...
September 29, 2017: Journal of Headache and Pain
https://www.readbyqxmd.com/read/28878937/contrast-sensitivity-to-spatial-gratings-in-moderate-and-dim-light-conditions-in-patients-with-diabetes-in-the-absence-of-diabetic-retinopathy
#12
Sare Safi, Anoushiravan Rahimi, Afsaneh Raeesi, Hamid Safi, Mohammad Aghazadeh Amiri, Mojtaba Malek, Mehdi Yaseri, Mohammad Haeri, Frank A Middleton, Eduardo Solessio, Hamid Ahmadieh
OBJECTIVE: To evaluate the ability of contrast sensitivity (CS) to discriminate loss of visual function in diabetic subjects with no clinical signs of retinopathy relative to that of normal subjects. RESEARCH DESIGN AND METHODS: In this prospective cross-sectional study, we measured CS in 46 diabetic subjects with a mean age of 48±6 years, a best-corrected visual acuity of 20/20 and no signs of diabetic retinopathy. The CS in these subjects was compared with CS measurements in 46 normal control subjects at four spatial frequencies (3, 6, 12, 18 cycles per degree) under moderate (500 lux) and dim (less than 2 lux) background light conditions...
2017: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/28878616/interim-results-of-a-multicenter-trial-with-the-new-electronic-subretinal-implant-alpha-ams-in-15-patients-blind-from-inherited-retinal-degenerations
#13
Katarina Stingl, Ruth Schippert, Karl U Bartz-Schmidt, Dorothea Besch, Charles L Cottriall, Thomas L Edwards, Florian Gekeler, Udo Greppmaier, Katja Kiel, Assen Koitschev, Laura Kühlewein, Robert E MacLaren, James D Ramsden, Johann Roider, Albrecht Rothermel, Helmut Sachs, Greta S Schröder, Jan Tode, Nicole Troelenberg, Eberhart Zrenner
Purpose: We assessed the safety and efficacy of a technically advanced subretinal electronic implant, RETINA IMPLANT Alpha AMS, in end stage retinal degeneration in an interim analysis of two ongoing prospective clinical trials. The purpose of this article is to describe the interim functional results (efficacy). Methods: The subretinal visual prosthesis RETINA IMPLANT Alpha AMS (Retina Implant AG, Reutlingen, Germany) was implanted in 15 blind patients with hereditary retinal degenerations at four study sites with a follow-up period of 12 months (www...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28877120/life-experiences-of-patients-with-glaucoma-a-phenomenological-study
#14
Emine Iyigun, Sevinc Tastan, Hatice Ayhan, Halise Coskun, Gulsah Kose, Tarkan Mumcuoglu
BACKGROUND: Studies that describe the experiences of patients with glaucoma from different cultures may help health professionals gain a broader perspective on this issue. Currently, few qualitative studies describe how patients with glaucoma in Turkey cope with daily life. PURPOSE: The aim of this study was to explore the experiences of patients with glaucoma. METHOD: This descriptive phenomenological study used purposive sampling to enroll 20 patients with glaucoma...
October 2017: Journal of Nursing Research: JNR
https://www.readbyqxmd.com/read/28874150/what-are-families-most-grateful-for-after-receiving-palliative-care-content-analysis-of-written-documents-received-a-chance-to-improve-the-quality-of-care
#15
María Aparicio, Carlos Centeno, José Miguel Carrasco, Antonio Barbosa, María Arantzamendi
BACKGROUND: Family members are involved in the care of palliative patients at home and therefore, should be viewed as important sources of information to help clinicians better understand the quality palliative care service patients receive. The objective of the study was to analyse what is valued most by family carers undergoing bereavement of a palliative care home service in order to identify factors of quality of care. METHODS: Qualitative exploratory study based on documentary analysis...
September 6, 2017: BMC Palliative Care
https://www.readbyqxmd.com/read/28861353/role-of-short-wavelength-filtering-lenses-in-delaying-myopia-progression-and-amelioration-of-asthenopia-in-juveniles
#16
Hai-Lan Zhao, Jin Jiang, Jie Yu, Hai-Ming Xu
AIM: To evaluate the positive effects of blue-violet light filtering lenses in delaying myopia and relieving asthenopia in juveniles. METHODS: Sixty ametropia juveniles (aged range, 11-15y) were randomized into two groups: the test group (30 children, 60 eyes), wearing blue-violet light filtering lenses; and the control group (30 children, 60 eyes), wearing ordinary aspherical lenses. Baseline refractive power of the affected eyes and axial length of the two groups was recorded...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28846552/qualitative-and-quantitative-evaluation-of-structural-myocardial-alterations-by-grating-based-phase-contrast-computed-tomography
#17
Susan Notohamiprodjo, Nicole Webber, Lorenz Birnbacher, Marian Willner, Manuel Viermetz, Julia Herzen, Mathias Marschner, Doris Mayr, Harald Bartsch, Tobias Saam, Sigrid Auweter, Franz Pfeiffer, Maximilian F Reiser, Holger Hetterich
OBJECTIVES: Grating-based phase-contrast computed tomography (gb-PCCT) relies on x-ray refraction instead of absorption to generate high-contrast images in biological soft tissue. The aim of this study was to evaluate the potential of gb-PCCT for the depiction of structural changes in heart disease. MATERIALS AND METHODS: Four human heart specimens from patients with hypertensive disease, ischemic disease, dilated heart disease, and cardiac lipomatosis were examined...
August 25, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/28737018/increased-myocardial-native-t1-relaxation-time-in-patients-with-nonischemic-dilated-cardiomyopathy-with-complex-ventricular-arrhythmia
#18
Shiro Nakamori, An H Bui, Jihye Jang, Hossam A El-Rewaidy, Shingo Kato, Long H Ngo, Mark E Josephson, Warren J Manning, Reza Nezafat
PURPOSE: To study the relationship between diffuse myocardial fibrosis and complex ventricular arrhythmias (ComVA) in patients with nonischemic dilated cardiomyopathy (NICM). We hypothesized that NICM patients with ComVA would have a higher native myocardial T1 time, suggesting more extensive myocardial diffuse fibrosis. MATERIALS AND METHODS: We prospectively enrolled NICM patients with a history of ComVA (n = 50) and age-matched NICM patients without ComVA (n = 57)...
July 24, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28713702/evidence-based-efficacy-of-autologous-grated-cartilage-in-primary-and-secondary-rhinoplasty
#19
Ali Manafi, Ali Kaviani, Zahra Sadat Hamedi, Afsaneh Rajabiani, Navid Manafi
BACKGROUND: There are numerous methods to mold and shape cartilage grafts for use in rhinoplasty. Each technique has advantages and disadvantages. We are going to introduce a new method for cartilage shaping with long lasting effects confirmed by follow up examination and pathologic evaluation. METHODS: Grated cartilage was used in 483 patients. For 89 cases, it was wrapped in fascia and in 394 patients, used as a filler per se or in contiguity with solid structural grafts...
May 2017: World Journal of Plastic Surgery
https://www.readbyqxmd.com/read/28637610/an-exploration-of-how-positive-emotions-are-expressed-by-older-people-and-nurse-assistants-in-homecare-visits
#20
Lena Heyn, Lee Ellington, Hilde Eide
OBJECTIVE: We don´t know how positive emotions are being expressed by patients and health care providers in consultations. The aim of this study is to identify positive emotions expressed by older people and nurse assistants to discuss the function of these in the visits. METHOD: This paper presents secondary analysis of consultations in the COMHOME project. In this pilot study, six transcribed consultations between nurse assistants and older people in home health care were analysed using a coding system for positive emotions with seven categories capturing both content and emotional intensity of positive affect...
November 2017: Patient Education and Counseling
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