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https://www.readbyqxmd.com/read/28215998/photosensitivity-in-generalized-epilepsies
#1
REVIEW
Shervonne Poleon, Jerzy P Szaflarski
Photosensitivity, which is the hallmark of photosensitive epilepsy (PSE), is described as an abnormal EEG response to visual stimuli known as a photoparoxysmal response (PPR). The PPR is a well-recognized phenomenon, occurring in 2-14% of patients with epilepsy but its pathophysiology is not clearly understood. PPR is electrographically described as 2-5Hz spike, spike-wave, or slow wave complexes with frontal and paracentral prevalence. Diagnosis of PPR is confirmed using intermittent photic stimulation (IPS) as well as video monitoring...
February 16, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28101401/human-heart-failure-biomarker-immunosensor-based-on-excessively-tilted-fiber-gratings
#2
Binbin Luo, Shengxi Wu, Zhonghao Zhang, Wengen Zou, Shenghui Shi, Mingfu Zhao, Nianbing Zhong, Yong Liu, Xue Zou, Lingling Wang, Weina Chai, Chuanmin Hu, Lin Zhang
A label-free immunosensor platform based on excessively tilted fiber gratings (Ex-TFGs) was developed for highly specific and fast detection of human N-terminal pro-B-type natriuretic peptide (NT-proBNP), which is considered a powerful biomarker for prognosis and risk stratification of heart failure (HF). High-purity anti-NT-proBNP monoclonal antibodies (MAbs) prepared in our laboratory were immobilized on fiber surface through the staphylococcal protein A (SPA) method for subsequent specific binding of the targeted NT-proBNP...
January 1, 2017: Biomedical Optics Express
https://www.readbyqxmd.com/read/28075341/a-non-invasive-multichannel-hybrid-fiber-optic-sensor-system-for-vital-sign-monitoring
#3
Marcel Fajkus, Jan Nedoma, Radek Martinek, Vladimir Vasinek, Homer Nazeran, Petr Siska
In this article, we briefly describe the design, construction, and functional verification of a hybrid multichannel fiber-optic sensor system for basic vital sign monitoring. This sensor uses a novel non-invasive measurement probe based on the fiber Bragg grating (FBG). The probe is composed of two FBGs encapsulated inside a polydimethylsiloxane polymer (PDMS). The PDMS is non-reactive to human skin and resistant to electromagnetic waves, UV absorption, and radiation. We emphasize the construction of the probe to be specifically used for basic vital sign monitoring such as body temperature, respiratory rate and heart rate...
January 8, 2017: Sensors
https://www.readbyqxmd.com/read/28071839/life-after-a-lung-transplant-a-balance-of-joy-and-challenges
#4
Jytte Graarup, Elin Lindberg Mogensen, Malene Missel, Selina Kikkenborg Berg
PURPOSE: To describe patients' experiences throughout the first four months post lung transplant. BACKGROUND: Health professionals are familiar with the fact that patients' average survival after a lung transplant is about seven years and that 74% of these patients reject new organs within the first two years. By contrast, knowledge of these patients' perspectives after lung transplantation is scant. DESIGN/METHOD: A qualitative study was conducted between May, 2013 and May, 2014 in which 26 interviewees participated - four months post-transplant - based on a semi-structured interview guide...
January 10, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28056389/altered-visual-contrast-gain-control-is-sensitive-for-idiopathic-generalized-epilepsies
#5
Daehan Won, Wonsuk Kim, W Art Chaovalitwongse, Jeffrey J Tsai
OBJECTIVE: Visual hyperexcitability in the form of abnormal contrast gain control has been shown in photosensitive epilepsy and idiopathic generalized epilepsies. We assessed the accuracy and reliability of measures of visual contrast gain control in discerning individuals with idiopathic generalized epilepsies from healthy controls. METHODS: Twenty-four adult patients with idiopathic generalized epilepsy and 32 neurotypical control subjects from two study sites participated in a prospective, cross-sectional study...
February 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/28048696/mo-fg-campus-iep3-01-evaluation-of-specific-absorption-rate-and-temperature-increase-induced-by-artificial-medical-implants-during-mri-scan
#6
Y Seo
PURPOSE: Heating of patients or burning of biological tissues around medical implants by RF power during MRI scan is a significant patient safety concern. The purpose of this study is to not only measure SAR values, but also RF-induced temperature elevation due to artificial hip joints during MRI scans. METHODS: SAR measurement experiment was performed on three discrete manufacturers at 1.5 and 3T. Three MRI RF sequences (T1w TSE, T2w inversion recovery, and T2w TSE) with imaging parameters were selected...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048337/we-fg-202-03-quantitative-ct-based-analysis-to-assess-lung-injury-following-proton-radiotherapy
#7
T Underwood, C Grassberger, H Willers, S MacDonald, R Jimenez, H Paganetti
PURPOSE: Relative to photon alternatives, the increased dose-conformity associated with proton therapy is expected to reduce the extent of radiation-induced lung toxicity. However, analysis of follow-up data is yet to be published in this area. In this study we retrospectively analyzed late-phase HU changes for proton therapy cohorts of chest wall and lung patients. METHODS: From our institution's register of patients treated using double-scattered protons, all chest wall and stereotactic lung cases (treated 2011-2012 and 2008-2014 respectively) were initially considered...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047507/su-f-i-27-measurement-of-sar-and-temperature-elevation-during-mri-scans
#8
Y Seo
PURPOSE: The poor reliability and repeatability of the manufacturer-reported SAR values on clinical MRI systems have been acknowledged. The purpose of this study is to not only measure SAR values, but also RF-induced temperature elevation at 1.5 and 3T MRI systems. METHODS: SAR measurement experiment was performed at 1.5 and 3T. Three MRI RF sequences (T1w TSE, T1w inversion recovery, and T2w TSE) with imaging parameters were selected. A hydroxyl-ethylcelluose (HEC) gelled saline phantom mimicking human body tissue was made...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047504/su-f-j-21-clinical-evaluation-of-surface-scanning-systems-in-different-treatment-locations
#9
T Moser, S Stefanowicz, B Rhein, D Oetzel, S Adeberg, L Koenig, R Wolf, S Rieken, C Karger
PURPOSE: To reduce imaging dose in fractionated IGRT, the ability of optical surface imaging systems (OSIS) to detect setup errors was tested. Therefore, clinical studies to evaluate for different treatment locations setup corrections derived by OSIS in comparison with x-ray image guidance in fractionated radiation therapy was performed. METHODS: The setup correction accuracy of an OSIS system (AlignRT, VisionRT, London, UK) will be analysed for the 4 tumour locations Pelvis, Upper Abdomen, Thorax and Breast, 20 patients for each location in comparison to a different system (Sentinel, C-RAD, SE)...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047401/tu-ab-202-07-a-novel-method-for-registration-of-mid-treatment-pet-ct-images-under-conditions-of-tumor-regression-for-patients-with-locally-advanced-lung-cancers
#10
Hoda Sharifi, Hong Zhang, Jian-Yyue Jin, Feng-Ming Kong, Indrin J Chetty, Hualiang Zhong
PURPOSE: In PET-guided adaptive radiotherapy (RT), changes in the metabolic activity at individual voxels cannot be derived until the duringtreatment CT images are appropriately registered to pre-treatment CT images. However, deformable image registration (DIR) usually does not preserve tumor volume. This may induce errors when comparing to the target. The aim of this study was to develop a DIR-integrated mechanical modeling technique to track radiation-induced metabolic changes on PET images...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28028188/feasibility-of-a-respiratory-movement-evaluation-tool-to-quantify-thoracoabdominal-movement-for-neuromuscular-diseases
#11
Fumio Liu, Michiyuki Kawakami, Kimimasa Tamura, Yoshihito Taki, Katsumi Shimizu, Tomoyoshi Otsuka, Tetsuya Tsuji, Chieko Miyata, Syoichi Tashiro, Ayako Wada, Katsuhiro Mizuno, Yoshimitsu Aoki, Meigen Liu
BACKGROUND: An objective method to evaluate thoracoabdominal movement is needed in daily clinical practice to detect patients at risk of hypoventilation and to allow for timely interventions in neuromuscular diseases. The clinical feasibility, reliability, and validity of a newly developed method for quantifying respiratory movement using fiber grating sensors, called the Respiratory Movement Evaluation Tool (RMET), was evaluated. METHODS: The time needed to measure respiratory movement and the usability of the measurement were determined by 5 clinicians using the Quebec User Evaluation of Satisfaction with Assistive Technology (QUEST) 2...
December 27, 2016: Respiratory Care
https://www.readbyqxmd.com/read/28009677/effectiveness-of-temporary-deafferentation-of-the-arm-on-somatosensory-and-motor-functions-following-stroke-a-systematic-review
#12
Emmanuelle Opsommer, Camille Zwissig, Natalya Korogod, Thomas Weiss
BACKGROUND: After stroke, regaining functional use of the upper limb can be challenging. Temporary deafferentation (TD) is a novel approach used in neurorehabilitation to voluntarily reduce the somatosensory input in a body part by temporary anesthesia; which has been shown to improve sensorimotor functions in the affected limb. OBJECTIVES: The primary objective of this systematic review was to present the best available evidence related to the effects of TD of the affected arm on the recovery of motor function and activity of the upper limb (arm and hand) following stroke...
December 2016: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/27992106/computational-modelling-of-clot-development-in-patient-specific-cerebral-aneurysm-cases-reply
#13
Malebogo N Ngoepe, Yiannis Ventikos
We are grateful to you for bringing this letter concerning our paper to our attention; similarly, we are grateful to Kremers et al for going through our work in such detail and making a series of interesting points. We take the comments raised by Kremers et al fully into account, and wish to address the issues raised. Of great importance in the design of a computational model of coagulation is the motivation behind the development of any such model. We have stated before and will reiterate the fact that we do not wish to make a contribution to the biochemical pathways that result in the formation of clots in cerebral aneurysms...
December 19, 2016: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/27932223/relationship-between-psychophysical-measures-of-retinal-ganglion-cell-density%C3%A2-and-in%C3%A2-vivo-measures-of-cone-density%C3%A2-in-glaucoma
#14
Juliane Matlach, Pádraig J Mulholland, Marketa Cilkova, Reena Chopra, Nilpa Shah, Tony Redmond, Steven C Dakin, David F Garway-Heath, Roger S Anderson
PURPOSE: Considerable between-individual variation in retinal ganglion cell (RGC) density exists in healthy individuals, making identification of change from normal to glaucoma difficult. In ascertaining local cone-to-RGC density ratios in healthy individuals, we wished to investigate the usefulness of objective cone density estimates as a surrogate of baseline RGC density in glaucoma patients, and thus a more efficient way of identifying early changes. DESIGN: Exploratory cohort study...
December 5, 2016: Ophthalmology
https://www.readbyqxmd.com/read/27877015/rainbow-glare-after-laser-assisted-in-situ-keratomileusis-a-review-of-literature
#15
REVIEW
Majid Moshirfar, Jordan D Desautels, Tyler S Quist, David F Skanchy, Mark T Williams, Ryan T Wallace
This article reviews the current literature pertaining to rainbow glare (RG), including incidence rate, clinical presentation, etiology, prognosis, and management. RG is a rare optical complication of femtosecond laser-assisted in situ keratomileusis that results in patients seeing an array of spectral bands surrounding point sources of light under mesopic and scotopic conditions. The mechanism is thought to be a consequence of the formation of a transmissive diffraction grating on the posterior surface of the corneal flap created by the FS laser...
2016: Clinical Ophthalmology
https://www.readbyqxmd.com/read/27857353/lens-gratings-for-dose-optimization-of-medical-x-ray-phase-contrast-imaging
#16
Oliver Preusche
A novel way to build arrays of X-ray lenslets is proposed for use in medical imaging, in particular for X-ray phase contrast imaging. Focusing on Talbot-Lau interferometers, this work is about patient dose reduction, especially for design energies above 50 keV. A low dose poses a fabrication problem, because it requires an analyzer grating which is both fine and high: It has to be fine for a good angular sensitivity. It has to be high to absorb well. However, gratings can currently be built either fine or high...
November 14, 2016: Optics Express
https://www.readbyqxmd.com/read/27767987/impaired-center-surround-suppression-in%C3%A2-patients-with-alzheimer-s-disease
#17
Xianbo Zhuang, Yanxiu Chen, Xianpeng Zhuang, Tao Xing, Tuanzhi Chen, Guisheng Jiang, Xiafeng Yang
Alzheimer's disease (AD) is often associated with declined visual processing abilities. Here we tested whether the functions of center-surround suppression- a hallmark property in the visual system- are altered by AD. To this end, we recruited three groups of participants (AD, elderly, and young) in a motion direction discrimination task, in which we measured the temporal duration threshold of a  drifting Gabor with varying stimulus sizes. We first replicated the phenomena of center-surround suppression that the required duration for discriminating a high contrast grating decreases with increasing stimulus size...
2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/27762611/gift-giving-in-the-podiatric-medical-student-patient-relationship
#18
Daniel López López, Paula Torreiro Pazo, Marta E Losa Iglesias, Ricardo Becerro de Bengoa Vallejo
We sought to explore the relationship between the podiatric medical student and the patient as it relates to the act of gift-giving as a sign of gratefulness for the services provided. This article presents the clinical case of a man who visited a podiatric medical student because of pain in his feet and subsequently presented the student with several gifts. Philanthropy, empathy, a positive attitude, treatment instructions, and the time devoted to the patient are some of the reasons why patients offer gifts to podiatric medical students...
September 2, 2016: Journal of the American Podiatric Medical Association
https://www.readbyqxmd.com/read/27731957/a-wolf-in-sheep-s-clothing-patients-and-healthcare-professionals-perceptions-of-oxygen-therapy-an-interpretative-phenomenological-analysis
#19
Carol A Kelly, Dave Lynes, Mary R O'Brien, Ben Shaw
BACKGROUND: Despite emerging evidence and guidelines, poor prescribing and administration of oxygen therapy persists. This study aimed to explore healthcare professionals' (HCPs) and patients' perceptions of oxygen. DESIGN: Semi-structured interviews with 28 patients and 34 HCPs. FINDINGS: Three master themes uncovered: oxygen as a panacea, the burden of oxygen and antecedents to beliefs. Patients used oxygen for breathlessness and as an enabler; they were grateful to oxygen and accepted it as part of the disease...
October 12, 2016: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/27562279/-application-of-disparity-discriminating-accuracy-test-in-evaluating-the-stereopsis-of-postoperative-intermittent-exotropia
#20
L X Feng, J Y Yao, L Chen, Y Tang, F Hou
OBJECTIVE: To discuss the application of disparity discriminating accuracy test in evaluating the stereopsis of postoperative intermittent exotropia. METHODS: Patients with intermittent exotropia who underwent surgery during July 2011 to June 2013 were followed up. The stereoacuity was examined by Titmus Stereotest, Randot Stereotest and Frisby Stereotest. Twenty adult cases whose stereoacuity reached normal were chosen as experimental group. Twenty healthy adults were selected as normal control group...
August 2016: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
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