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https://www.readbyqxmd.com/read/29342505/reply-to-does-rheumatoid-arthritis-cause-an-obesity-paradox
#1
Jeffrey A Sparks, Elizabeth W Karlson
We are grateful to Dr. Baker and colleagues for their interest in our recent work and agree with their interpretation of our study that investigated weight change in the early rheumatoid arthritis (RA) period among women diagnosed with RA and matched comparators. As they point out, any weight loss and severe weight loss in the early RA or matched index period were both more common among those with RA than matched comparators. The authors suggest that this increased frequency of weight loss may exacerbate the obesity paradox for mortality among patients with RA...
January 17, 2018: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/29333113/grating-oriented-line-wise-filtration-golf-for-dual-energy-x-ray-ct
#2
Yan Xi, Wenxiang Cong, Daniel Harrison, Ge Wang
In medical X-ray Computed Tomography (CT), the use of two distinct X-ray source spectra (energies) allows dose-reduction and material discrimination relative to that achieved with only one source spectrum. Existing dual-energy CT methods include source kVp-switching, double-layer detection, dual-source gantry, and two-pass scanning. Each method suffers either from strong spectral correlation or patient-motion artifacts. To simultaneously address these problems, we propose to improve CT data acquisition with the Grating Oriented Line-wise Filtration (GOLF) method, a novel X-ray filter that is placed between the source and patient...
December 2017: Sensing and Imaging
https://www.readbyqxmd.com/read/29325518/experiences-of-gestational-diabetes-and-gestational-diabetes-care-a-focus-group-and-interview-study
#3
Judith Parsons, Katherine Sparrow, Khalida Ismail, Katharine Hunt, Helen Rogers, Angus Forbes
BACKGROUND: Gestational diabetes mellitus (GDM) is an increasingly common condition of pregnancy. It is associated with adverse fetal, infant and maternal outcomes, as well as an increased risk of GDM in future pregnancies and type 2 diabetes for both mother and offspring. Previous studies have shown that GDM can result in an emotionally distressing pregnancy, but there is little research on the patient experience of GDM care, especially of a demographically diverse UK population. The aim of this research was to explore the experiences of GDM and GDM care for a group of women attending a large diabetes pregnancy unit in southeast London, UK, in order to improve care...
January 11, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29324431/a-descriptive-qualitative-study-to-assess-patient-experiences-following-stoma-reversal-after-rectal-cancer-surgery
#4
Maria Reinwalds, Andrea Blixter, Eva Carlsson
Standard surgical treatment for patients operated for rectal cancer is abdominoperineal excision of the tumor result- ing in a permanent colostomy or an anterior resection, often with construction of a temporary loop ileostomy. Both options impact bowel function. Living with a permanent colostomy has been studied in depth, but knowledge is limited about patients' experiences living with a resected rectum after stoma reversal and how it affects daily life. A qualitative study was conducted to describe the rst 4 to 6 weeks after reversal of a temporary loop ileostomy due to rectal cancer...
December 2017: Ostomy/wound Management
https://www.readbyqxmd.com/read/29311009/cortical-inhibitory-function-in-cervical-dystonia
#5
Christos Ganos, Elisa R Ferrè, Angela Marotta, Panagiotis Kassavetis, John Rothwell, Kailash P Bhatia, Patrick Haggard
OBJECTIVE: To assess the specificity of cortical inhibitory deficits in cervical dystonia patients. METHODS: A systematic test battery was developed to assess spatial and temporal aspects of cortical inhibition, in motor and somatosensory systems of the hand. We tested 17 cervical dystonia (CD) patients and 19 controls assessing somatosensory spatial inhibition (grating orientation test, interdigital feedforward subliminal inhibition), somatosensory temporal inhibition (temporal discrimination threshold, feedforward subliminal inhibition), motor spatial inhibition (surround inhibition), and motor temporal inhibition (short interval intracortical inhibition)...
December 1, 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/29284362/a-retrospective-review-of-fall-risk-factors-in-the-bone-marrow-transplant-inpatient-service
#6
Cory M Vela, Lisa M Grate, Ali McBride, Steven Devine, Leslie A Andritsos
Purpose The purpose of this study was to compare medications and potential risk factors between patients who experienced a fall during hospitalization compared to those who did not fall while admitted to the Blood and Marrow Transplant inpatient setting at The James Cancer Hospital. Secondary objectives included evaluation of transplant-related disease states and medications in the post-transplant setting that may lead to an increased risk of falls, post-fall variables, and number of tests ordered after a fall...
January 1, 2017: Journal of Oncology Pharmacy Practice
https://www.readbyqxmd.com/read/29279651/mesopic-quality-of-vision-after-accelerated-18-mw-cm2-corneal-cross-linking-mid-term-results
#7
Hassan Hashemi, Mohammad Miraftab, Soheila Asgari
PURPOSE: The purpose of the study was to determine 2-year changes in mesopic higher-order aberrations (HOAs) and contrast sensitivity (CS) after accelerated corneal cross-linking (CXL) in keratoconus patients. MATERIALS AND METHODS: In this before-after interventional case series, patients with progressive keratoconus were subjected to accelerated CXL (18 mW/cm2, 5 min). Patients were examined with the OPD-Scan III and CVS-1000 grating charts under mesopic conditions at baseline and at 12 and 24 months after CXL...
July 2017: Middle East African Journal of Ophthalmology
https://www.readbyqxmd.com/read/29258166/pofbg-embedded-cork-insole-for-plantar-pressure-monitoring
#8
Débora Vilarinho, Antreas Theodosiou, Cátia Leitão, Arnaldo G Leal-Junior, Maria de Fátima Domingues, Kyriacos Kalli, Paulo André, Paulo Antunes, Carlos Marques
We propose a novel polymer optical fiber (POF) sensing system based on fiber Bragg gratings (FBGs) to measure foot plantar pressure. The plantar pressure signals are detected by five FBGs, in the same piece of cyclic transparent optical polymer (CYTOP) fiber, which are embedded in a cork insole for the dynamic monitoring of gait. The calibration and measurements performed with the suggested system are presented, and the results obtained demonstrate the accuracy and reliability of the sensing platform to monitor the foot plantar pressure distribution during gait motion and the application of pressure...
December 16, 2017: Sensors
https://www.readbyqxmd.com/read/29225520/epilepsy-treatment-a-futurist-view
#9
Michael Privitera
Advances in epilepsy treatment are occurring at a rapid pace, and it is challenging for us to keep up with the latest in our field. As we struggle to keep up with the literature and concentrate on our own research and clinical work, we often fail to exercise our imagination and envision what our field will be like in future decades. This was the assignment to the speakers for the Presidential Symposium at the 2016 American Epilepsy Society Annual Meeting. I challenged the experts to step outside the frame of their usual daily work to imagine what epilepsy treatment would and should look like for the next generation of epilepsy specialists and their patients...
July 2017: Epilepsy Currents
https://www.readbyqxmd.com/read/29190019/visual-evoked-potentials-in-glaucoma-and-alzheimer-s-disease
#10
Elisa Cerri, Carlotta Fabiani, Chiara Criscuolo, Luciano Domenici
Visual responses to gratings alternating in contrast have been studied in humans and several mammalian species. Previous evidence from human patients and animal models of neurodegeneration has highlighted the importance to record simultaneously the pattern electroretinogram (P-ERG) and visual evoked cortical potentials (VEPs) to investigate retinal and post-retinal sites of neurodegeneration.In view of the increasing importance of research on experimental models of neurodegenerative diseases, we present here the parametric properties of visual evoked responses in animal models of glaucoma and Alzheimer's disease...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29134296/p300-based-acuity-estimation-in-imitated-amblyopia
#11
Marvin L Beusterien, Sven P Heinrich
PURPOSE: A frequent approach to estimating visual acuity objectively is the recording of visual evoked potentials (VEPs) to patterns of different coarseness. This, however, overestimates acuity in patients with fragmented and distorted vision such as in amblyopia. This is likely due to VEP-based techniques using checkerboard or grating stimuli. We hypothesized that no overestimation would occur when the event-related potential P300 in response to optotype stimuli is used for acuity estimation...
November 13, 2017: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/29134137/pattern-electroretinography-and-visual-evoked-potentials-provide-clinical-evidence-of-cns-modulation-of-high-and-low-contrast-vep-latency-in-glaucoma
#12
William E Sponsel, Susan L Johnson, Rick Trevino, Alberto Gonzalez, Sylvia L Groth, Carolyn Majcher, Diane C Fulton, Matthew A Reilly
Purpose: Both pattern electroretinography (PERG) and visual evoked potentials (VEP) can be performed using low- (15%; Lc) and high- (85%; Hc) contrast gratings that may preferentially stimulate the magno- and parvocellular pathways. We observed that among glaucomatous patients showing only one VEP latency deficit per eye, there appeared to be a very strong tendency for an Hc delay in one eye and an Lc delay in the other. Methods: Diopsys NOVA-LX system was used to measure VEP Hc and Lc latency among a clinical glaucoma population to find all individuals with either a single Hc or Lc latency abnormality in each eye (group 1), or with greater than 0 and less than 4 Hc or Lc VEP latency abnormalities in the two eyes (group 2) to determine whether a significant inverse correlation existed for these values in either group...
2017: Translational Vision Science & Technology
https://www.readbyqxmd.com/read/29125983/functional-differences-between-healthy-and-diabetic-endothelial-cells-on-topographical-cues
#13
Marie F A Cutiongco, Bryan M X Chua, Dawn J H Neo, Muhammad Rizwan, Evelyn K F Yim
The endothelial lining of blood vessels is severely affected in type II diabetes. Yet, there is still a paucity on the use of diabetic endothelial cells for study and assessment of implantable devices targeting vascular disease. This critically impairs our ability to determine appropriate topographical cues to be included in implantable devices that can be used to maintain or improve endothelial cell function in vivo. Here, the functional responses of healthy and diabetic human coronary arterial endothelial cells were studied and observed to differ depending on topography...
October 25, 2017: Biomaterials
https://www.readbyqxmd.com/read/29124460/medical-egg-freezing-the-importance-of-a-patient-centered-approach-to-fertility-preservation
#14
Marcia C Inhorn, Daphna Birenbaum-Carmeli, Lynn M Westphal, Joseph Doyle, Norbert Gleicher, Dror Meirow, Hila Raanani, Martha Dirnfeld, Pasquale Patrizio
PURPOSE: This binational qualitative study of medical egg freezing (MEF) examined women's motivations and experiences, including their perceived needs for patient-centered care in the midst of fertility- and life-threatening diagnoses. METHODS: Forty-five women who had undertaken MEF were interviewed in the USA (33 women) and in Israel (12 women) between June 2014 and August 2016. Interviews lasted approximately 1 h and were conducted by two senior medical anthropologists, one in each country...
November 9, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/29120714/functional-magnetic-resonance-imaging-to-assess-neuroadaptation-to-multifocal-intraocular-lenses
#15
Andreia M Rosa, Ângela C Miranda, Miguel M Patrício, Colm McAlinden, Fátima L Silva, Miguel Castelo-Branco, Joaquim N Murta
PURPOSE: To evaluate the use of functional magnetic resonance imaging (MRI) to assess neuroadaptation to multifocal intraocular lenses (IOLs). SETTING: Faculty of Medicine, University of Coimbra, Coimbra, Portugal. DESIGN: Prospective case study. METHODS: Patients with bilateral diffractive IOL implantation after cataract surgery had functional MRI at postoperative intervals of 3 weeks and 6 months. A nonintervention control group was included as proof of concept...
October 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/29110946/assessment-of-the-electronic-retinal-implant-alpha-ams-in-restoring-vision-to-blind-patients-with-end-stage-retinitis-pigmentosa
#16
Thomas L Edwards, Charles L Cottriall, Kanmin Xue, Matthew P Simunovic, James D Ramsden, Eberhart Zrenner, Robert E MacLaren
PURPOSE: To report the initial efficacy results of the Retina Implant Alpha AMS (Retina Implant AG, Reutlingen, Germany) for partial restoration of vision in end-stage retinitis pigmentosa (RP). DESIGN: Prospective, single-arm, investigator-sponsored interventional clinical trial. Within-participant control comprising residual vision with the retinal implant switched ON versus OFF in the implanted eye. PARTICIPANTS: The Retina Implant Alpha AMS was implanted into the worse-seeing eye of 6 participants with end-stage RP and no useful perception of light vision...
October 27, 2017: Ophthalmology
https://www.readbyqxmd.com/read/29060024/robust-tracking-of-dexterous-continuum-robots-fusing-fbg-shape-sensing-and-stereo-vision
#17
Rumei Zhang, Hao Liu, Jianda Han
Robust and efficient tracking of continuum robots is important for improving patient safety during space-confined minimally invasive surgery, however, it has been a particularly challenging task for researchers. In this paper, we present a novel tracking scheme by fusing fiber Bragg grating (FBG) shape sensing and stereo vision to estimate the position of continuum robots. Previous visual tracking easily suffers from the lack of robustness and leads to failure, while the FBG shape sensor can only reconstruct the local shape with integral cumulative error...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28987906/visually-evoked-responses-from-the-blind-field-of-hemianopic-patients
#18
Javier Sanchez-Lopez, Caterina A Pedersini, Francesco Di Russo, Nicolò Cardobi, Cristina Fonte, Valentina Varalta, Massimo Prior, Nicola Smania, Silvia Savazzi, Carlo A Marzi
Hemianopia is a visual field defect characterized by decreased vision or blindness in the contralesional visual field of both eyes. The presence of well documented above-chance unconscious behavioural responses to visual stimuli presented to the blind hemifield (blindsight) has stimulated a great deal of research on the neural basis of this important phenomenon. The present study is concerned with electrophysiological responses from the blind field. Since previous studies found that transient Visual Evoked Potentials (VEPs) are not entirely suitable for this purpose here we propose to use Steady-State VEPs (SSVEPs)...
October 5, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/28979077/developing-an-integrated-treatment-pathway-for-a-post-coronary-artery-bypass-grating-cabg-geriatric-patient-with-comorbid-hypertension-and-type-1-diabetes-mellitus-for-treating-acute-hypoglycemia-and-electrolyte-imbalance
#19
Atta Abbas Naqvi, Amna Shah, Rizwan Ahmad, Niyaz Ahmad
INTRODUCTION: The ailments afflicting the elderly population is a well-defined specialty of medicine. It calls for an immaculately designed health-care plan to treat diseases in geriatrics. For chronic illnesses such as diabetes mellitus (DM), coronary heart disease, and hypertension (HTN), they require proper management throughout the rest of patient's life. An integrated treatment pathway helps in treatment decision-making and improving standards of health care for the patient. CASE PRESENTATION: This case describes an exclusive clinical pharmacist-driven designing of an integrated treatment pathway for a post-coronary artery bypass grafting (CABG) geriatric male patient with DM type I and HTN for the treatment of hypoglycemia and electrolyte imbalance...
July 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/28972542/the-ohio-contrast-cards-visual-performance-in-a-pediatric-low-vision-site
#20
Gregory R Hopkins, Bradley E Dougherty, Angela M Brown
SIGNIFICANCE: This report describes the first clinical use of the Ohio Contrast Cards, a new test that measures the maximum spatial contrast sensitivity of low-vision patients who cannot recognize and identify optotypes and for whom the spatial frequency of maximum contrast sensitivity is unknown. PURPOSE: To compare measurements of the Ohio Contrast Cards to measurements of three other vision tests and a vision-related quality-of-life questionnaire obtained on partially sighted students at Ohio State School for the Blind...
October 2017: Optometry and Vision Science: Official Publication of the American Academy of Optometry
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