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https://www.readbyqxmd.com/read/28878937/contrast-sensitivity-to-spatial-gratings-in-moderate-and-dim-light-conditions-in-patients-with-diabetes-in-the-absence-of-diabetic-retinopathy
#1
Sare Safi, Anoushiravan Rahimi, Afsaneh Raeesi, Hamid Safi, Mohammad Aghazadeh Amiri, Mojtaba Malek, Mehdi Yaseri, Mohammad Haeri, Frank A Middleton, Eduardo Solessio, Hamid Ahmadieh
OBJECTIVE: To evaluate the ability of contrast sensitivity (CS) to discriminate loss of visual function in diabetic subjects with no clinical signs of retinopathy relative to that of normal subjects. RESEARCH DESIGN AND METHODS: In this prospective cross-sectional study, we measured CS in 46 diabetic subjects with a mean age of 48±6 years, a best-corrected visual acuity of 20/20 and no signs of diabetic retinopathy. The CS in these subjects was compared with CS measurements in 46 normal control subjects at four spatial frequencies (3, 6, 12, 18 cycles per degree) under moderate (500 lux) and dim (less than 2 lux) background light conditions...
2017: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/28878616/interim-results-of-a-multicenter-trial-with-the-new-electronic-subretinal-implant-alpha-ams-in-15-patients-blind-from-inherited-retinal-degenerations
#2
Katarina Stingl, Ruth Schippert, Karl U Bartz-Schmidt, Dorothea Besch, Charles L Cottriall, Thomas L Edwards, Florian Gekeler, Udo Greppmaier, Katja Kiel, Assen Koitschev, Laura Kühlewein, Robert E MacLaren, James D Ramsden, Johann Roider, Albrecht Rothermel, Helmut Sachs, Greta S Schröder, Jan Tode, Nicole Troelenberg, Eberhart Zrenner
Purpose: We assessed the safety and efficacy of a technically advanced subretinal electronic implant, RETINA IMPLANT Alpha AMS, in end stage retinal degeneration in an interim analysis of two ongoing prospective clinical trials. The purpose of this article is to describe the interim functional results (efficacy). Methods: The subretinal visual prosthesis RETINA IMPLANT Alpha AMS (Retina Implant AG, Reutlingen, Germany) was implanted in 15 blind patients with hereditary retinal degenerations at four study sites with a follow-up period of 12 months (www...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28877120/life-experiences-of-patients-with-glaucoma-a-phenomenological-study
#3
Emine Iyigun, Sevinc Tastan, Hatice Ayhan, Halise Coskun, Gulsah Kose, Tarkan Mumcuoglu
BACKGROUND: Studies that describe the experiences of patients with glaucoma from different cultures may help health professionals gain a broader perspective on this issue. Currently, few qualitative studies describe how patients with glaucoma in Turkey cope with daily life. PURPOSE: The aim of this study was to explore the experiences of patients with glaucoma. METHOD: This descriptive phenomenological study used purposive sampling to enroll 20 patients with glaucoma...
October 2017: Journal of Nursing Research: JNR
https://www.readbyqxmd.com/read/28874150/what-are-families-most-grateful-for-after-receiving-palliative-care-content-analysis-of-written-documents-received-a-chance-to-improve-the-quality-of-care
#4
María Aparicio, Carlos Centeno, José Miguel Carrasco, Antonio Barbosa, María Arantzamendi
BACKGROUND: Family members are involved in the care of palliative patients at home and therefore, should be viewed as important sources of information to help clinicians better understand the quality palliative care service patients receive. The objective of the study was to analyse what is valued most by family carers undergoing bereavement of a palliative care home service in order to identify factors of quality of care. METHODS: Qualitative exploratory study based on documentary analysis...
September 6, 2017: BMC Palliative Care
https://www.readbyqxmd.com/read/28861353/role-of-short-wavelength-filtering-lenses-in-delaying-myopia-progression-and-amelioration-of-asthenopia-in-juveniles
#5
Hai-Lan Zhao, Jin Jiang, Jie Yu, Hai-Ming Xu
AIM: To evaluate the positive effects of blue-violet light filtering lenses in delaying myopia and relieving asthenopia in juveniles. METHODS: Sixty ametropia juveniles (aged range, 11-15y) were randomized into two groups: the test group (30 children, 60 eyes), wearing blue-violet light filtering lenses; and the control group (30 children, 60 eyes), wearing ordinary aspherical lenses. Baseline refractive power of the affected eyes and axial length of the two groups was recorded...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28846552/qualitative-and-quantitative-evaluation-of-structural-myocardial-alterations-by-grating-based-phase-contrast-computed-tomography
#6
Susan Notohamiprodjo, Nicole Webber, Lorenz Birnbacher, Marian Willner, Manuel Viermetz, Julia Herzen, Mathias Marschner, Doris Mayr, Harald Bartsch, Tobias Saam, Sigrid Auweter, Franz Pfeiffer, Maximilian F Reiser, Holger Hetterich
OBJECTIVES: Grating-based phase-contrast computed tomography (gb-PCCT) relies on x-ray refraction instead of absorption to generate high-contrast images in biological soft tissue. The aim of this study was to evaluate the potential of gb-PCCT for the depiction of structural changes in heart disease. MATERIALS AND METHODS: Four human heart specimens from patients with hypertensive disease, ischemic disease, dilated heart disease, and cardiac lipomatosis were examined...
August 25, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/28737018/increased-myocardial-native-t1-relaxation-time-in-patients-with-nonischemic-dilated-cardiomyopathy-with-complex-ventricular-arrhythmia
#7
Shiro Nakamori, An H Bui, Jihye Jang, Hossam A El-Rewaidy, Shingo Kato, Long H Ngo, Mark E Josephson, Warren J Manning, Reza Nezafat
PURPOSE: To study the relationship between diffuse myocardial fibrosis and complex ventricular arrhythmias (ComVA) in patients with nonischemic dilated cardiomyopathy (NICM). We hypothesized that NICM patients with ComVA would have a higher native myocardial T1 time, suggesting more extensive myocardial diffuse fibrosis. MATERIALS AND METHODS: We prospectively enrolled NICM patients with a history of ComVA (n = 50) and age-matched NICM patients without ComVA (n = 57)...
July 24, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28713702/evidence-based-efficacy-of-autologous-grated-cartilage-in-primary-and-secondary-rhinoplasty
#8
Ali Manafi, Ali Kaviani, Zahra Sadat Hamedi, Afsaneh Rajabiani, Navid Manafi
BACKGROUND: There are numerous methods to mold and shape cartilage grafts for use in rhinoplasty. Each technique has advantages and disadvantages. We are going to introduce a new method for cartilage shaping with long lasting effects confirmed by follow up examination and pathologic evaluation. METHODS: Grated cartilage was used in 483 patients. For 89 cases, it was wrapped in fascia and in 394 patients, used as a filler per se or in contiguity with solid structural grafts...
May 2017: World Journal of Plastic Surgery
https://www.readbyqxmd.com/read/28637610/an-exploration-of-how-positive-emotions-are-expressed-by-older-people-and-nurse-assistants-in-homecare-visits
#9
Lena Heyn, Lee Ellington, Hilde Eide
OBJECTIVE: We don´t know how positive emotions are being expressed by patients and health care providers in consultations. The aim of this study is to identify positive emotions expressed by older people and nurse assistants to discuss the function of these in the visits. METHOD: This paper presents secondary analysis of consultations in the COMHOME project. In this pilot study, six transcribed consultations between nurse assistants and older people in home health care were analysed using a coding system for positive emotions with seven categories capturing both content and emotional intensity of positive affect...
November 2017: Patient Education and Counseling
https://www.readbyqxmd.com/read/28626250/association-between-changes-in-visual-evoked-magnetic-fields-and-non-motor-features-in-parkinson-s-disease
#10
Yoshiro Fujisawa, Tomomi Minato, Jun-Ichi Uemura, Minoru Hoshiyama, Hirohisa Watanabe, Masaaki Hirayama
Visual dysfunction can be caused by several abnormalities, including dysfunctions in the visual cortex and retina. Our aim was to investigate changes in visual evoked brain responses in the primary visual cortex associated with Parkinson's disease (PD). Sixteen healthy control subjects and ten patients with PD participated in this study. We assessed the visual evoked magnetic field (VEF) using magnetoencephalography (MEG). Checkerboard pattern reversal (CPR) and monotonous grating pattern (MGP) stimulations were used...
February 2017: Nagoya Journal of Medical Science
https://www.readbyqxmd.com/read/28609417/visually-evoked-potential-markers-of-concussion-history-in-patients-with-convergence-insufficiency
#11
Dmitri Poltavski, Paul Lederer, Laurie Kopko Cox
PURPOSE: We investigated whether differences in the pattern visual evoked potentials exist between patients with convergence insufficiency and those with convergence insufficiency and a history of concussion using stimuli designed to differentiate between magnocellular (transient) and parvocellular (sustained) neural pathways. METHODS: Sustained stimuli included 2-rev/s, 85% contrast checkerboard patterns of 1- and 2-degree check sizes, whereas transient stimuli comprised 4-rev/s, 10% contrast vertical sinusoidal gratings with column width of 0...
July 2017: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/28588445/lights-from-the-dark-neural-responses-from-a-blind-visual-hemifield
#12
Alice Bollini, Javier Sanchez-Lopez, Silvia Savazzi, Carlo A Marzi
Here we present evidence that a hemianopic patient with a lesion of the left primary visual cortex (V1) showed an unconscious above-chance orientation discrimination with moving rather than static visual gratings presented to the blind hemifield. The patient did not report any perceptual experience of the stimulus features except for a feeling that something appeared in the blind hemifield. Interestingly, in the lesioned left hemisphere, following stimulus presentation to the blind hemifield, we found an event-related potential (ERP) N1 component at a post-stimulus onset latency of 180-260 ms and a source generator in the left BA 19...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28553559/next-generation-perg-method-expanding-the-response-dynamic-range-and-capturing-response-adaptation
#13
Pedro Monsalve, Giacinto Triolo, Jonathon Toft-Nielsen, Jorge Bohorquez, Amanda D Henderson, Rafael Delgado, Edward Miskiel, Ozcan Ozdamar, William J Feuer, Vittorio Porciatti
PURPOSE: To compare a new method for steady-state pattern electroretinogram (PERGx) with a validated method (PERGLA) in normal controls and in patients with optic neuropathy. METHODS: PERGx and PERGLA were recorded in a mixed population (n = 33, 66 eyes) of younger controls (C1; n = 10, age 38 ± 8.3 years), older controls (C2; n = 11, 57.9 ± 8.09 years), patients with early manifest glaucoma (G; n = 7, 65.7 ±11.6 years), and patients with nonarteritic ischemic optic neuropathy (N; n = 5, mean age 59...
May 2017: Translational Vision Science & Technology
https://www.readbyqxmd.com/read/28489248/intact-fgf23-and-%C3%AE-klotho-during-acute-inflammation-sepsis-in-ckd-patients
#14
LETTER
Evangelia Dounousi, Claudia Torino, Patrizia Pizzini, Sebastiano Cutrupi, Vincenzo Panuccio, Graziella D'Arrigo, Samar Abd ElHafeez, Giovanni Tripepi, Francesca Mallamaci, Carmine Zoccali
No abstract text is available yet for this article.
June 2017: European Journal of Clinical Investigation
https://www.readbyqxmd.com/read/28470774/incidental-findings-in-research-a-focus-group-study-about-the-perspective-of-the-research-participant
#15
Anna W de Boer, Yvonne M Drewes, Renée de Mutsert, Mattijs E Numans, Martin den Heijer, Olaf M Dekkers, Albert de Roos, Hildo J Lamb, Jeanet W Blom, Ria Reis
PURPOSE: To explore the experiences and preferences of population-based research participants to whom an incidental finding was communicated. MATERIALS AND METHODS: Of the 2580 participants of the Netherlands Epidemiology of Obesity (NEO) study who underwent magnetic resonance imaging (MRI) scanning of the abdomen, heart, and/or brain, an incidental finding with presumed health importance was disclosed to 56 (2%) participants. These participants were invited to discuss their experiences regarding the communication of the finding by the NEO research team in a focus group discussion...
May 4, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28433446/functional-magnetic-resonance-imaging-to-assess-the-neurobehavioral-impact-of-dysphotopsia-with-multifocal-intraocular-lenses
#16
Andreia M Rosa, Ângela C Miranda, Miguel Patrício, Colm McAlinden, Fátima L Silva, Joaquim N Murta, Miguel Castelo-Branco
PURPOSE: To investigate the association between dysphotopsia and neural responses in visual and higher-level cortical regions in patients who recently received multifocal intraocular lens (IOL) implants. DESIGN: Cross-sectional study. PARTICIPANTS: Thirty patients 3 to 4 weeks after bilateral cataract surgery with diffractive IOL implantation and 15 age- and gender-matched control subjects. METHODS: Functional magnetic resonance imaging (fMRI) was performed when participants viewed low-contrast grating stimuli...
September 2017: Ophthalmology
https://www.readbyqxmd.com/read/28424058/family-members-of-deceased-palliative-care-patients-receiving-bereavement-anniversary-cards-a-survey-on-the-recipient-s-reactions-and-opinions
#17
Swantje Goebel, Sandra Stephanie Mai, Christina Gerlach, Ulrike Windschmitt, Karl-Heinz Feldmann, Martin Weber
BACKGROUND: Bereavement support is part of palliative care. Sending out bereavement anniversary cards is one intervention of follow-up support for the bereaved. This study evaluated the suitability of bereavement anniversary cards as an appropriate method in bereavement care. METHODS: A questionnaire was sent to each card recipient since the starting point of this practice (October 2014-June 2015). Data was analyzed descriptively. RESULTS: 24 of 68 deliverable questionnaires were returned (response rate 35%)...
April 19, 2017: BMC Palliative Care
https://www.readbyqxmd.com/read/28409230/binocular-rivalry-transitions-predict-inattention-symptom-severity-in-adult-adhd
#18
Aiste Jusyte, Natalia Zaretskaya, Nina Maria Höhnle, Andreas Bartels, Michael Schönenberg
Attention deficit and hyperactivity disorder (ADHD) is a prevalent childhood disorder that is often maintained throughout the development and persists into adulthood. Established etiology models suggest that deficient inhibition underlies the core ADHD symptoms. While experimental evidence for impaired motor inhibition is overwhelming, little is known about the sensory inhibition processes, their changes throughout the development, and the relationship to ADHD symptoms. Here, we used the well-established binocular rivalry (BR) paradigm to investigate for the very first time the inhibitory processes related to visual perception in adults with ADHD...
April 13, 2017: European Archives of Psychiatry and Clinical Neuroscience
https://www.readbyqxmd.com/read/28379541/resistance-to-apoptosis-and-autophagy-leads-to-enhanced-survival-in-sertoli-cells
#19
Ferial Aslani, Tim Sebastian, Miguel Keidel, Suada Fröhlich, Hans-Peter Elsässer, Hans-Christian Schuppe, Jörg Klug, Poornima Mahavadi, Monika Fijak, Martin Bergmann, Andreas Meinhardt, Sudhanshu Bhushan
STUDY QUESTION: What is the underlying mechanism of Sertoli cell (SC) resistance to cell death? SUMMARY ANSWER: High expression of prosurvival B-cell lymphoma-2 (BCL2) proteins and inhibition of apoptosis and autophagy prolongs SC survival upon exposure to stress stimuli. WHAT IS KNOWN ALREADY: In human and in experimental models of orchitis, tolerogenic SC survive stress conditions, while germ cells undergo massive apoptosis. In general, non-dividing highly differentiated cells tend to resist stress conditions for a longer time by favoring activation of prosurvival mechanisms and inhibition of cell death pathways...
June 1, 2017: Molecular Human Reproduction
https://www.readbyqxmd.com/read/28303505/patient-reported-outcomes-10%C3%A2-years-after-roux-en-y-gastric-bypass
#20
Florence E Turrentine, James H Mehaffey, Rachel L Mehaffey, Matthew G Mullen, Bruce D Schirmer, Peter T Hallowell
BACKGROUND: Following weight-loss surgery, patients who failed to achieve or sustain weight loss have nevertheless reported high satisfaction with their long-term bariatric experience. Understanding this phenomenon better will likely improve patients' experiences. OBJECTIVE: The purpose of this study was to explore patients' long-term experiences following bariatric surgery. SETTING: A 604-bed academic health system in the USA. METHODS: Participants rated satisfaction and shared spontaneous comments regarding their gastric bypass experience...
March 16, 2017: Obesity Surgery
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