keyword
https://read.qxmd.com/read/38486961/antipsychotic-prescribing-patterns-in-children-and-adolescents-attending-australian-general-practice-in-2011-and-2017
#1
JOURNAL ARTICLE
Julie Klau, David Gonzalez-Chica, Melissa Raven, Jon Jureidini
BACKGROUND: Antipsychotics are increasingly prescribed to children and adolescents worldwide, but little is known about reasons for prescribing. We aimed to examine patterns of paediatric antipsychotic prescribing in Australian primary care services in 2011 and 2017, including diagnoses, sociodemographic characteristics, off-label prescribing, and psychotropic co-prescribing. METHODS: Retrospective analysis of electronic health records (EHRs) using a large Australian general practice database (MedicineInsight)...
March 2024: JCPP Adv
https://read.qxmd.com/read/38126083/treatment-guesses-in-the-treatment-for-adolescents-with-depression-study-accuracy-unblinding-and-influence-on-outcomes
#2
JOURNAL ARTICLE
Jon Jureidini, Joanna Moncrieff, Julie Klau, Natalie Aboustate, Melissa Raven
OBJECTIVE: We evaluated the presence and impact of unblinding during the influential Treatment for Adolescents with Depression Study (ClinicalTrials.gov Identifier: NCT00006286). METHOD: Our analysis was part of a Restoring Invisible and Abandoned Trials reanalysis. Treatment for Adolescents with Depression Study trialled fluoxetine, placebo, cognitive behaviour therapy or their combination, in treating adolescents with major depressive disorder. We analysed the accuracy of guesses of fluoxetine or placebo allocation, and their effects on change in Children's Depression Rating Scale-Revised at 12 weeks...
December 21, 2023: Australian and New Zealand Journal of Psychiatry
https://read.qxmd.com/read/37182907/dispensing-of-psychotropic-medications-to-australian-children-and-adolescents-before-and-during-the-covid-19-pandemic-2013-2021-a-retrospective-cohort-study
#3
JOURNAL ARTICLE
Stephen J Wood, Jenni Ilomäki, Jacqueline Gould, George Sq Tan, Melissa Raven, Jon N Jureidini, Luke E Grzeskowiak
OBJECTIVE: To determine longitudinal patterns of dispensing of antidepressant, anxiolytic, antipsychotic, psychostimulant, and hypnotic/sedative medications to children and adolescents in Australia during 2013-2021. DESIGN: Retrospective cohort study; analysis of 10% random sample of Pharmaceutical Benefits Scheme (PBS) dispensing data. PARTICIPANTS, SETTING: People aged 18 years or younger dispensed PBS-subsidised psychotropic medications in Australia, 2013-2021...
May 14, 2023: Medical Journal of Australia
https://read.qxmd.com/read/34963342/trends-in-prescription-of-psychotropic-medications-to-children-and-adolescents-in-australian-primary-care-from-2011-to-2018
#4
JOURNAL ARTICLE
Julie Klau, Carla De Oliveira Bernardo, David Alejandro Gonzalez-Chica, Melissa Raven, Jon Jureidini
OBJECTIVE: To examine trends in prescribing psychotropic medications to children and adolescents in Australian primary care from 2011 to 2018. METHOD: A retrospective cohort study examined prescriptions written by general practitioners using MedicineInsight, a large Australian primary care database, covering approximately 9% of all general practitioner practices. Numbers of patients receiving prescriptions for five main classes of psychotropics (antipsychotics, antidepressants, attention deficit hyperactivity disorder medications, anxiolytics, and hypnotics/sedatives [including benzodiazepines and Z-drugs, but excluding melatonin]) were examined annually by age-group (0-4, 5-9, 10-14, 15-18 years)...
December 28, 2021: Australian and New Zealand Journal of Psychiatry
https://read.qxmd.com/read/34719437/barriers-to-access-to-clinical-trial-data-obstruction-of-a-riat-reanalysis-of-the-treatment-for-adolescents-with-depression-study
#5
JOURNAL ARTICLE
Natalie Aboustate, Jon Jureidini
BACKGROUND: Public access to data has been a major step in attempting to reduce bias in scientific literature. OBJECTIVE: Data to verify efficacy outcomes are now more accessible; however, little has been done to ensure public access to harms data from RCTs, which are equally important in ascertaining possible misreporting and protecting safety. METHODS: The treatment for adolescents with depression study (TADS) has influenced most international practice guidelines for treating children and adolescents with depression, supporting first-line prescription of fluoxetine in combination with cognitive behavioural therapy (CBT)...
October 26, 2021: International Journal of Risk & Safety in Medicine
https://read.qxmd.com/read/34672887/the-maternal-looking-guide-a-perinatal-clinical-tool-to-support-the-emerging-mother-infant-relationship
#6
JOURNAL ARTICLE
Patricia O'Rourke, Jon Jureidini, David Ben-Tovim
BACKGROUND: This study explores maternal looking - the unidirectional looking by a mother at her newborn - as a precursor to mother-infant gaze. METHODS: Phase 1 used video as a means of detailed and disciplined observation to examine how mothers look at their newborns (n = 13). Using an iterative design, intensive analysis identified and categorised patterns of looking and looking-related behaviours. This resulted in a typology of looking. Phase 2 subjected the typology to inter-rater reliability testing, with midwives as multiple raters (n = 24), using the typology to rate standardised tapes of mothers and newborns (n = 10)...
October 21, 2021: Journal of Reproductive and Infant Psychology
https://read.qxmd.com/read/32587531/antidepressant-prescribing-and-suicide-self-harm-by-young-australians-regulatory-warnings-contradictory-advice-and-long-term-trends
#7
REVIEW
Martin Whitely, Melissa Raven, Jon Jureidini
In 2004, the US Food and Drug Administration (FDA) controversially issued a black box warning that antidepressants were associated with an increased risk of suicidal thoughts and behaviours in people aged under 18 years. In 2007, the warning was expanded to include young adults aged under 25 years. In 2005, the Australian Therapeutic Goods Administration responded to the FDA warning by requiring Product and Consumer Information leaflets to be updated to reflect the risk. However, there was considerable debate, and at times emotive backlash, in academic journals and the international media...
2020: Frontiers in Psychiatry
https://read.qxmd.com/read/31651818/national-partnership-for-maternal-safety-consensus-bundle-on-venous-thromboembolism
#8
LETTER
Adam C Urato, Elia Abi-Jaoude, John Abramson, Harrison Alter, Louise B Andrew, David Antonuccio, Lisa Bero, Pierre Biron, Laura S Boylan, Alain Braillon, James M Brophy, Shannon Brownlee, Alan Cassels, Robert Cook-Deegan, Lisa Cosgrove, Luca De Fiore, Richard A Deyo, Adam Elshaug, Cindy Farquhar, Daniel M Fatovich, Eileen Fingerman, Juan Gérvas, Peter C Gøtzsche, Rafael Gracia, Iona Heath, David U Himmelstein, Jerome R Hoffman, Teppo Järvinen, Jon Jureidini, Andrew Kotaska, Thomas Kuehlein, Jeanne Lenzer, Susan Levenstein, Joel Lexchin, Barbara Mintzes, Florian Naudet, Manon Niquette, Lusy Paulyna Orellana Navarrete, Cynthia A Pearson, Geneviève Rail, Richard Roberts, Naman Shah, Vera Sharav, Jay Siwek, Stefan Topolski, Alexander C Tsai
No abstract text is available yet for this article.
November 2019: Obstetrics and Gynecology
https://read.qxmd.com/read/30848663/why-a-rights-based-approach-is-not-anti-psychiatry
#9
JOURNAL ARTICLE
Lisa Cosgrove, Jon Jureidini
No abstract text is available yet for this article.
June 2019: Australian and New Zealand Journal of Psychiatry
https://read.qxmd.com/read/30488716/doubling-a-model-for-international-clinical-partnerships
#10
JOURNAL ARTICLE
Jon Jureidini, Julie Stone, Molly Jureidini
OBJECTIVES: This article draws attention to an initiative aimed at benefiting colleagues in developing countries, through financial and/or moral support. It describes an attempt to engage The Royal College of Australian and New Zealand Psychiatrists ('the College') in supporting this philanthropic activity. It further aims to attract interest from the College and fellows in contributing to international philanthropy. CONCLUSIONS: Doubling provides a credible model for facilitating better mental health care in situations where there are trained staff but inadequate resources...
February 2019: Australasian Psychiatry: Bulletin of Royal Australian and New Zealand College of Psychiatrists
https://read.qxmd.com/read/30317644/attention-deficit-hyperactivity-disorder-late-birthdate-effect-common-in-both-high-and-low-prescribing-international-jurisdictions-systematic-review
#11
REVIEW
Martin Whitely, Melissa Raven, Sami Timimi, Jon Jureidini, John Phillimore, Jonathan Leo, Joanna Moncrieff, Patrick Landman
BACKGROUND: Multiple studies have found that the youngest children in a classroom are at elevated risk of being diagnosed with, or medicated for, ADHD. This systematic review was conducted to investigate whether this late birthdate effect is the norm and whether the strength of effect is related to the absolute risk of being diagnosed/medicated. METHODS: A literature search of the PubMed and ERIC databases and snowball and grey literature searching were conducted...
October 14, 2018: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://read.qxmd.com/read/29987082/mental-health-messages-in-prominent-mental-health-apps
#12
JOURNAL ARTICLE
Lisa Parker, Lisa Bero, Donna Gillies, Melissa Raven, Barbara Mintzes, Jon Jureidini, Quinn Grundy
PURPOSE: Many who seek primary health care advice about mental health may be using mobile applications (apps) claiming to improve well-being or relieve symptoms. We aimed to identify how prominent mental health apps frame mental health, including who has problems and how they should be managed. METHODS: We conducted a qualitative content analysis of advertising material for mental health apps found online in the United States, the United Kingdom, Canada, and Australia during late 2016...
July 2018: Annals of Family Medicine
https://read.qxmd.com/read/29865094/paediatric-antidepressants-benefits-and-risks
#13
REVIEW
David Healy, Joanna Le Noury, Jon Jureidini
The data supporting the use of "antidepressants" in children and adolescents is largely unavailable. Academic publications give a different picture as regards benefits and harms to publications from regulatory other sources. Despite disagreements about the data driving use of these medicines, in practice "antidepressants" may now be the most commonly used drugs by adolescent girls, and children's mental health services are attracting increasing attention.This paper reviews the difficulties surrounding the data...
2019: International Journal of Risk & Safety in Medicine
https://read.qxmd.com/read/29432499/industry-corrupted-psychiatric-trials
#14
REVIEW
Jay D Amsterdam, Leemon B McHenry, Jon N Jureidini
The goal of this paper is to expose the research misconduct of pharmaceutical industry sponsored clinical trials via three short case studies of corrupted psychiatric trials that were conducted in the United States. We discuss the common elements that enable the misrepresentation of clinical trial results including ghostwriting for medical journals, the role of key opinion leaders as co-conspirators with the pharmaceutical industry and the complicity of top medical journals in failing to uphold standards of science and peer review...
December 30, 2017: Psychiatria Polska
https://read.qxmd.com/read/27670832/data-transparency-in-clinical-trials-implications-of-restoring-study-329
#15
JOURNAL ARTICLE
Jon Jureidini
No abstract text is available yet for this article.
December 2016: Australian and New Zealand Journal of Psychiatry
https://read.qxmd.com/read/27662279/study-329-continuation-phase-safety-and-efficacy-of-paroxetine-and-imipramine-in-extended-treatment-of-adolescent-major-depression
#16
RANDOMIZED CONTROLLED TRIAL
Joanna Le Noury, John M Nardo, David Healy, Jon Jureidini, Melissa Raven, Catalin Tufanaru, Elia Abi-Jaoude
OBJECTIVE: This is an analysis of the unpublished continuation phase of Study 329, the primary objective of which was to compare the efficacy and safety of paroxetine and imipramine with placebo in the treatment of adolescents with unipolar major depression. The objectives of the continuation phase were to assess safety and relapse rates in the longer term. The objective of this publication, under the Restoring Invisible and Abandoned Trials (RIAT) initiative, was to see whether access to and analysis of the previously unpublished dataset from the continuation phase of this randomized controlled trial would have clinically relevant implications for evidence-based medicine...
September 17, 2016: International Journal of Risk & Safety in Medicine
https://read.qxmd.com/read/27289173/antidepressants-fail-but-no-cause-for-therapeutic-gloom
#17
COMMENT
Jon Jureidini
No abstract text is available yet for this article.
August 27, 2016: Lancet
https://read.qxmd.com/read/27176755/the-citalopram-cit-md-18-pediatric-depression-trial-deconstruction-of-medical-ghostwriting-data-mischaracterisation-and-academic-malfeasance
#18
JOURNAL ARTICLE
Jon N Jureidini, Jay D Amsterdam, Leemon B McHenry
OBJECTIVE: Deconstruction of a ghostwritten report of a randomized, double-blind, placebo-controlled efficacy and safety trial of citalopram in depressed children and adolescents conducted in the United States. METHODS: Approximately 750 documents from the Celexa and Lexapro Marketing and Sales Practices Litigation: Master Docket 09-MD-2067-(NMG) were deconstructed. RESULTS: The published article contained efficacy and safety data inconsistent with the protocol criteria...
March 16, 2016: International Journal of Risk & Safety in Medicine
https://read.qxmd.com/read/26376805/restoring-study-329-efficacy-and-harms-of-paroxetine-and-imipramine-in-treatment-of-major-depression-in-adolescence
#19
RANDOMIZED CONTROLLED TRIAL
Joanna Le Noury, John M Nardo, David Healy, Jon Jureidini, Melissa Raven, Catalin Tufanaru, Elia Abi-Jaoude
OBJECTIVES: To reanalyse SmithKline Beecham's Study 329 (published by Keller and colleagues in 2001), the primary objective of which was to compare the efficacy and safety of paroxetine and imipramine with placebo in the treatment of adolescents with unipolar major depression. The reanalysis under the restoring invisible and abandoned trials (RIAT) initiative was done to see whether access to and reanalysis of a full dataset from a randomised controlled trial would have clinically relevant implications for evidence based medicine...
September 16, 2015: BMJ: British Medical Journal
https://read.qxmd.com/read/25390273/let-children-cry
#20
JOURNAL ARTICLE
Jon N Jureidini
No abstract text is available yet for this article.
November 17, 2014: Medical Journal of Australia
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