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https://www.readbyqxmd.com/read/17011986/genetic-expression-profiles-and-chromosomal-alterations-in-sporadic-breast-cancer-in-mexican-women
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Adán Valladares, Normand García Hernández, Fabio Salamanca Gómez, Everardo Curiel-Quezada, Eduardo Madrigal-Bujaidar, Ma Dolores Vergara, Mónica Sierra Martínez, Diego J Arenas Aranda
Breast cancer is the second-leading cause of death among Mexican women >35 years of age. At the molecular level, changes in many genetic pathways have been reported to be associated with this neoplasm. To analyze these changes, we determined gene expression profiles and chromosomal structural alterations in tumors from Mexican women. We obtained mRNA to identify expression profiles with microarray technology, and DNA to determine amplifications and deletions, in 10 fresh sporadic breast tumor biopsies without treatment, as well as in 10 nonaffected breast tissues...
October 15, 2006: Cancer Genetics and Cytogenetics
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