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https://www.readbyqxmd.com/read/29657849/talar-process-fractures-an-overview-and-update-of-the-literature
#1
Haroon Majeed, Donald J McBride
Fractures of the lateral and the posterior processes of the talus are uncommon and frequently missed because of a low level of suspicion and difficulty in interpretation on plain radiographs. Missed fractures can lead to persistent pain and reduced function.Lateral process fractures are usually a consequence of forced dorsiflexion and inversion of fixed pronated foot. These are also commonly known as snowboarder's fractures.The posterior process of the talus is composed of medial and lateral tubercles, separated by the groove for the flexor hallucis longus tendon...
March 2018: EFORT Open Reviews
https://www.readbyqxmd.com/read/29657482/functional-and-radiological-outcome-in-management-of-compound-tibia-diaphyseal-fracture-with-ao-monolateral-fixator-versus-limb-reconstruction-system
#2
Hitesh J Mangukiya, Neetin P Mahajan, Eknath D Pawar, Aakash Mane, Jitsen Manna
Introduction: Tibia being the most common fractured long bone represents 36.7% of all long bone fractures in adults with open fracture comprises 23.5% of all tibial shaft fracture. The lack of the muscular covering over anteromedial aspect of the tibia and poor blood supply predispose open tibial fractures to a 10-20 fold increased risk of developing infection than open fracture in any other anatomical areas and a nonunion rate as high as 28% has been reported in the literature. Methods: We did a prospective study at our institute from 2014-2016 comprising 40 patients with compound tibia diaphyseal fracture managed with AO monolateral external fixator (Group 1) (n = 20) and Limb reconstruction system (Group 2) (n = 20) as primary and definitive tool...
March 2018: Journal of Orthopaedics
https://www.readbyqxmd.com/read/29656239/mechanical-alterations-of-the-bone-cartilage-unit-in-a-rabbit-model-of-early-osteoarthrosis
#3
Sarah Pragnère, Caroline Boulocher, Ophélie Pollet, Catherine Bosser, Aurélie Levillain, Magali Cruel, Thierry Hoc
OBJECTIVE: The purpose of this study was to assess mechanical properties along with microstructural modifications of the hyaline cartilage (HC), calcified cartilage (CC) and cortical plate (Ct.Pt), in an anterior cruciate ligament transection (ACLT) model. Medial femoral condyles of six healthy rabbits (control group) and of six ACLT rabbits 6 weeks after OA induction were explanted. The zone of interest (ZOI) for all experiments was defined as the weight bearing areas of the samples...
April 3, 2018: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29655901/in-vivo-heterotopic-culturing-of-prefabricated-tendon-grafts-with-mechanical-stimulation-in-a-sheep-model
#4
M Petri, P Lu, M Omar, M Ettinger, C Krettek, C Neunaber, M Jagodzinski
BACKGROUND: The goal of this study is to investigate the biomechanical and histological properties of in vivo heterotopically prefabricated cruciate ligament replacement grafts with and without mechanical stimulation. The clinical goal is to heterotopically prefabricate a bone-tendon-bone graft for anterior cruciate ligament reconstruction, which allows rapid ingrowth and early full weight bearing. METHODS: In a sheep model, eight quadriceps tendon grafts were harvested and introduced into culture chambers at their proximal and distal ends...
April 11, 2018: Knee
https://www.readbyqxmd.com/read/29650034/complex-fracture-orthopedic-rehabilitation-comfort-real-time-visual-biofeedback-on-weight-bearing-versus-standard-training-methods-in-the-treatment-of-proximal-femur-fractures-in-the-elderly-study-protocol-for-a-multicenter-randomized-controlled-trial
#5
Marco Raaben, Syaiful Redzwan, Robin Augustine, Taco Johan Blokhuis
BACKGROUND: Proximal femur fractures are a common injury after low energy trauma in the elderly. Most rehabilitation programs are based on restoring mobility and early resumption of weight-bearing. However, therapy compliance is low in patients following lower extremity fractures. Moreover, little is known about the relevance of gait parameters and how to steer the rehabilitation after proximal femur fractures in the elderly. Therefore, the aim of this prospective, randomized controlled trial is to gain insight in gait parameters and evaluate if real-time visual biofeedback can improve therapy compliance after proximal femur fractures in the elderly...
April 12, 2018: Trials
https://www.readbyqxmd.com/read/29629582/arthroscopically-assisted-fixation-of-hawkins-type-ii-talar-neck-fractures
#6
J Wagener, C Schweizer, L Zwicky, T Horn Lang, B Hintermann
Aims Arthroscopically controlled fracture reduction in combination with percutaneous screw fixation may be an alternative approach to open surgery to treat talar neck fractures. The purpose of this study was thus to present preliminary results on arthroscopically reduced talar neck fractures. Patients and Methods A total of seven consecutive patients (four women and three men, mean age 39 years (19 to 61)) underwent attempted surgical treatment of a closed Hawkins type II talar neck fracture using arthroscopically assisted reduction and percutaneous screw fixation...
April 1, 2018: Bone & Joint Journal
https://www.readbyqxmd.com/read/29627930/flexor-digitorum-longus-tendon-transfer-to-the-navicular-tendon-to-tendon-repair-is-stronger-compared-with-interference-screw-fixation
#7
Daniel Marsland, Joanna M Stephen, Toby Calder, Andrew A Amis, James D F Calder
PURPOSE: To assess whether early rehabilitation could be safe after flexor digitorum longus (FDL) tendon transfer, the current biomechanical study aimed to measure tendon displacement under cyclic loading and load to failure, comparing a traditional tendon-to-tendon (TT) repair with interference screw fixation (ISF). METHODS: 24 fresh-frozen cadaveric below knee specimens underwent FDL tendon transfer. In 12 specimens a TT repair was performed via a navicular bone tunnel...
April 7, 2018: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29623237/cementless-stem-for-femoral-neck-fractures-in-a-patient-s-10th-decade-of-life-high-rate-of-periprosthetic-fractures
#8
Method Kabelitz, Yannick Fritz, Patrick Grueninger, Christoph Meier, Patrick Fries, Michael Dietrich
Background: Subsidence of cementless femoral stems in hemiarthroplasty (HA) and increased fracture rates are ongoing concerns of orthopedic surgeons when treating fractures in very old patients. Additionally, bone cement implantation syndrome may result in perioperative cardiac or pulmonary complications, especially in older patients, leading to morbidity and mortality. This study was performed to analyze possible subsidence and intraoperative fractures in a cohort of very old patients treated with cementless stems...
2018: Geriatric Orthopaedic Surgery & Rehabilitation
https://www.readbyqxmd.com/read/29600202/late-and-vague-presentation-of-septic-arthritis-of-hip-in-a-ivdrug-abuser
#9
Anantha Krishnan Raghupathi, Avinash Joshi
Introduction: Septic arthritis of the hip is a rare entity in acute presentation of hip pain in adults. Even though hip is the second most commonly affected joint, adult patients with septic arthritis not related to a surgical procedure represent <0.00001% of total acute admissions. Case Report: We present a 32-year-old female intravenous drug abuser, positive for Hepatitis B and C who had started to inject her femoral veins 2 years ago. She presented with a 10 weeks history of radiating pain in the leg which was full, constant and diffuse in nature with hip stiffness...
November 2017: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/29582098/high-reported-rate-of-return-to-play-following-bone-marrow-stimulation-for-osteochondral-lesions-of-the-talus
#10
REVIEW
Eoghan T Hurley, Yoshiharu Shimozono, Niall P McGoldrick, Charles L Myerson, Youichi Yasui, John G Kennedy
PURPOSE: The purpose of this study is to systematically review the literature and to evaluate the reported rehabilitation protocols, return to play guidelines and subsequent rates and timing of return to play following bone marrow stimulation (BMS) for osteochondral lesions of the talus (OLT). METHODS: MEDLINE, EMBASE and the Cochrane Library were searched according to the PRISMA guidelines in September 2017. The rate and timing of return to play was assessed. The rehabilitation protocols were recorded, including time to start range of motion, partial weight-bearing and complete weight-bearing...
March 26, 2018: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29579286/involvement-of-heparanase-in-the-pathogenesis-of-mesothelioma-basic-aspects-and-clinical-applications
#11
Uri Barash, Moshe Lapidot, Yaniv Zohar, Cynthia Loomis, Andre Moreira, Sari Feld, Chandra Goparaju, Haining Yang, Edward Hammond, Ganlin Zhang, Jin-Ping Li, Neta Ilan, Arnon Nagler, Harvey I Pass, Israel Vlodavsky
Background: Mammalian cells express a single functional heparanase, an endoglycosidase that cleaves heparan sulfate and thereby promotes tumor metastasis, angiogenesis, and inflammation. Malignant mesothelioma is highly aggressive and has a poor prognosis because of the lack of markers for early diagnosis and resistance to conventional therapies. The purpose of this study was to elucidate the mode of action and biological significance of heparanase in mesothelioma and test the efficacy of heparanase inhibitors in the treatment of this malignancy...
March 21, 2018: Journal of the National Cancer Institute
https://www.readbyqxmd.com/read/29572182/opening-wedge-high-tibial-osteotomy-performed-with-locking-plate-fixation-tomofix%C3%A2-and-early-weight-bearing-but-without-filling-the-defect-a-concise-follow-up-note-of-48-cases-at-10-years-follow-up
#12
M Darées, S Putman, T Brosset, T Roumazeille, G Pasquier, H Migaud
INTRODUCTION: Use of a locking plate during medial-opening high tibial osteotomy (HTO) eliminates the need to fill the defect and its associated complications. It also allows early weight bearing. Since long-term data with this type of construct are rare, we wanted to report the outcomes of a 51-patient cohort evaluated after a mean follow-up of 10.2 years. The goals were to determine 1) the HTO survival and whether the correction was maintained between 2 and 10 years later, 2) the stability of the functional outcomes, 3) the complication rate related to use of locking plates...
March 20, 2018: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/29557918/aerobic-exercise-during-early-murine-doxorubicin-exposure-mitigates-cardiac-toxicity
#13
Fei Wang, Brian Iskra, Eugenie Kleinerman, Claudia Alvarez-Florez, Thomas Andrews, Angela Shaw, Joya Chandra, Keri Schadler, Gregory J Aune
We report the cardioprotective effects of moderate aerobic exercise from parallel pediatric murine models of doxorubicin (Doxo) exposure in non-tumor-bearing immune competent (NTB-IC) mice and tumor-bearing nude mice (TB-NM). In both models, animals at 4 weeks of age underwent Doxo treatment with or without 2 weeks of simultaneous exercise. In sedentary NTB-IC or TB-NM mice, Doxo treatment resulted in a statistically significant decrease in ejection fraction and fractional shortening compared with control animals...
April 2018: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/29557867/early-clinical-and-radiographic-outcomes-of-trabecular-metal-total-ankle-replacement-using-a-transfibular-approach
#14
Alexej Barg, Clayton C Bettin, Albert H Burstein, Charles L Saltzman, Jeremy Gililland
BACKGROUND: In the last 2 decades, total ankle replacement has gained greater acceptance as a treatment option in patients with end-stage ankle osteoarthritis. However, there is a lack of literature on total ankle replacement using a lateral transfibular approach. Therefore, we sought to report early clinical and radiographic results for a patient cohort treated with total ankle replacement using a lateral transfibular approach, performed by a single surgeon. METHODS: From October 2012 to December 2014, 55 primary total ankle arthroplasties using the Zimmer Trabecular Metal Total Ankle implant were performed in 54 patients (29 male and 25 female; mean age, 67...
March 21, 2018: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/29556273/short-term-outcomes-of-reconstruction-subsequent-to-intercalary-resection-of-femoral-diaphyseal-metastatic-tumor-with-pathological-fracture-comparison-between-segmental-allograft-and-intercalary-prosthesis
#15
Deng-Xing Lun, Yong-Cheng Hu, Xiong-Gang Yang, Feng Wang, Zhao-Wan Xu
Reconstruction of bone defects following femoral diaphyseal tumor resection is challenging. Segmental allograft (SA) and intercalary prosthesis (IP) are the most common reconstruction methods for femoral diaphyseal metastatic tumors with pathological fracture. However, whether the complications and functional outcomes differ between SA and IP remains unclear. To compare the clinical outcomes and complications for patients treated with SA reconstruction or IP replacement for femoral shaft tumors, 34 patients who had undergone intercalary resection for metastatic tumor with pathological fracture in the femoral diaphysis were evaluated...
March 2018: Oncology Letters
https://www.readbyqxmd.com/read/29555559/opening-wedge-high-tibial-osteotomy-without-bone-grafting-in-severe-varus-osteoarthritic-knee-rate-and-risk-factors-of-non-union-in-41-cases
#16
R Siboni, P Beaufils, P Boisrenoult, C Steltzlen, N Pujol
INTRODUCTION: Using locking plates in opening-wedge high tibial osteotomy (OWHTO) via a medial opening theoretically allows early weight-bearing without need for bone or bone-substitute grafting. It incurs a risk of non-consolidation in case of large correction (> 10°), although rates and risk factors of non-union are not known. The present retrospective study compared OWHTO with correction <10° versus >10°, with a view to determining: 1) complications rates (non-union) according to degree of correction, and 2) risk factors for such complications...
March 16, 2018: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/29551653/complex-fractures-of-the-acetabulum-should-the-enlarged-iliofemoral-approach-be-abandoned-results-at-20-years-follow-up
#17
A-G Hue, R Gauthé, A-C Tobenas-Dujardin, A Vallée, J Mouton, F Dujardin
INTRODUCTION: Among the various options for internal fixation of acetabular fractures, the enlarged iliofemoral approach is less often used, being more invasive, although providing greater exposure enabling control of all components in complex fractures. Even so, the impact of its invasiveness has not been confirmed, and long-term results are not known. We therefore performed a retrospective study, aiming 1) to assess long-term functional outcome, and 2) to assess associated morbidity...
March 15, 2018: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/29523122/modified-essex-lopresti-procedure-with-percutaneous-calcaneoplasty-for-comminuted-intra-articular-calcaneal-fractures-a-retrospective-case-analysis
#18
Jen-Ta Shih, Chun-Lin Kuo, Tsu-Te Yeh, Hsain-Chung Shen, Ru-Yu Pan, Chia-Chun Wu
BACKGROUND: The ideal treatment for comminuted intraarticular calcaneal fractures is still debated. Open reduction and internal fixation (ORIF) is the most popular surgical procedure; however, wound complications, implant choice, and infection remain major concerns. This study aimed to demonstrate the results of an innovative, minimally invasive surgical procedure, namely, a closed reduction technique using large-diameter Steinmann pins and percutaneous calcaneoplasty using injectable calcium sulfate cement (MIIG X3, Wright Medical Technology, Inc...
March 9, 2018: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29521811/carbenoxolone-as-a-novel-therapy-for-attenuation-of-cancer-induced-bone-pain
#19
Sarah Falk
Pain is a major complication for cancer patients significantly compromising their quality of life. Current treatment is far from optimal and particularly bone-related cancer pain poses an increasing clinical and socio-economical problem. Connexins, key proteins in cell-cell communication, have the potential to affect cancer-induced bone pain at multiple levels, including nociceptive signaling and bone degradation. This study tested the analgesic potential of carbenoxolone, a broad-acting connexin blocker, in a mouse model of cancer-induced bone pain...
March 6, 2018: Pain
https://www.readbyqxmd.com/read/29519630/initial-support-with-no-immobilisation-as-therapy-of-choice-for-fractures-of-the-fifth-metatarsal
#20
I Úbeda-Pérez de Heredia
AIM: To demonstrate the effectiveness of early weight bearing with no immobilisation (functional therapy) applied to fractures of the fifth metatarsal. MATERIAL AND METHOD: A retrospective case and control observational study was performed among 382 fractures on the fifth metatarsal comparing functional, conservative-orthopaedic and surgical treatments. Fractures were classified according to the settlement on the distal, diaphyseal or proximal part of the bone, the recommended therapy and the treatment performed...
March 5, 2018: Revista Española de Cirugía Ortopédica y Traumatología
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