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https://www.readbyqxmd.com/read/28732218/invasiveness-of-tibial-bone-graft-harvesting-for-secondary-alveolar-bone-grafting-can-harvesting-be-made-at-the-age-of-less-than-10%C3%A2-years-without-complications
#1
Kohta Fukuta, Kenichi Kurita, Atsushi Nakayama, Masahito Maeda, Hiroshi Watanabe, Mitsuo Goto
PURPOSE: In this study, particulate cancellous bone marrow was harvested from the tibia for alveolar bone grafting, and postoperative complications at the donor site were compared between patients aged 10 years or older (29 tibias) and those aged younger than 10 years (42 tibias). PATIENTS AND METHODS: Enrolled patients were those who underwent tibial bone graft harvesting at the Department of Oral and Maxillofacial Surgery, Aichi Gakuin University, during a period of 3 years and 1 month from March 2012 through March 2015...
June 24, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28726121/bone-marrow-oedema-predicts-bone-collapse-in-paediatric-and-adolescent-leukaemia-patients-with-corticosteroid-induced-osteonecrosis
#2
Ashok Joseph Theruvath, Preeti Arun Sukerkar, Shanshan Bao, Jarrett Rosenberg, Sandra Luna-Fineman, Sandhya Kharbanda, Heike Elisabeth Daldrup-Link
OBJECTIVES: Corticosteroid treatment of paediatric leukaemia patients can lead to osteonecrosis (ON). We determined whether bone marrow oedema (BME) is an early sign of progressive ON and eventual bone collapse. METHODS: In a retrospective study, two radiologists reviewed MR imaging characteristics of 47 early stage epiphyseal ON in 15 paediatric and adolescent leukaemia patients. Associations between BME on initial imaging studies and subchondral fracture, disease progression and bone collapse were assessed by Cochran-Mantel-Haenszel tests...
July 19, 2017: European Radiology
https://www.readbyqxmd.com/read/28712981/judo-practice-in-early-age-promotes-high-level-of-bone-mass-acquisition-of-growing-boys-skeleton
#3
Kawther Missawi, Mohamed Zouch, Hamada Chaari, Yosra Chakroun, Zouhair Tabka, Elyès Bouajina
The current study aimed to exhibit effects of judo training for at least 2 yr on bone mass parameters in growing boys. Our population was composed of one hundred and thirty boys in tanner stage 1 and aged 10.52 ± 0.86 yr. Eleven judo players were therefore, excluded from the study because they do not have participate regularly to the judo training sessions during the last 2 yr. The resting sample was divided into two groups: 50 judo players (JU group) and 69 controls (C group). Bone mineral density (BMD), bone mineral content (BMC), and bone area (BA) were evaluated by using dual-photon X-ray absorptiometry on weight-bearing sites: the whole body, lumbar spine (L2-L4), legs, femoral necks and hips and on the non-weight bearing sites: arms and radiuses...
July 13, 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28697074/repair-of-bimalleolar-ankle-fracture
#4
Nina Fisher, Abiola Atanda, Stephanie Swensen, Kenneth A Egol
PURPOSE: The incidence of ankle fractures is rapidly increasing in geriatric populations. Of the 4 fracture patterns described by the Lauge-Hansen classification system, supination-external rotation (SER) accounts for most ankle fractures. This video demonstrates surgical repair of a SER type 4 ankle fracture in a geriatric patient. METHODS: SER type 4 ankle fractures are considered unstable and are generally treated with surgical fixation. After placement of plate and screws, intraoperative stress tests can be used to assess for syndesmotic widening...
August 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28696002/mitochondrial-dysfunction-is-an-acute-response-of-articular-chondrocytes-to-mechanical-injury
#5
Michelle L Delco, Edward D Bonnevie, Lawrence J Bonassar, Lisa A Fortier
Mitochondrial (MT) dysfunction is known to occur in chondrocytes isolated from end-stage osteoarthritis (OA) patients, but the role of MT dysfunction in the initiation and early pathogenesis of post-traumatic OA (PTOA) remains unclear. The objective of this study was to investigate chondrocyte MT function immediately following mechanical injury in cartilage, and to determine if the response to injury differed between a weight bearing region (medial femoral condyle; MFC) and a non-weight bearing region (distal patellofemoral groove; PFG) of the same joint...
July 11, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/28673102/open-reduction-assisted-with-an-external-fixator-and-internal-fixation-with-calcaneal-locking-plate-for-intra-articular-calcaneal-fractures
#6
Hui Yao, Huading Lu, Huiqing Zhao, Lulu Lv, Gang Hou
BACKGROUND: The extensile lateral approach (ELA) has been considered to be a standard approach for displaced intra-articular calcaneal fractures (DICF) because it provides excellent exposure and allows direct reduction of the depressed posterior facet fragment. But continuous retraction during surgery needs sufficient manpower and may cause ischemia. Failure of rigid fixation of DICF will not allow for early weight bearing and may lead to a loss of reduction. To avoid these disadvantages, this study presents open reduction assisted with an external fixator and internal fixation with a calcaneal locking plate...
June 1, 2017: Foot & Ankle International
https://www.readbyqxmd.com/read/28666042/primary-total-knee-arthroplasty-for-distal-femur-fractures-a-systematic-review-of-indications-implants-techniques-and-results
#7
Foster Chen, Robert Li, Ajay Lall, Evan M Schwechter
Distal femur fractures (DFFs) in elderly patients historically were difficult to treat because of osteoporotic bone, comminution, and intra-articular involvement. Current surgical treatment options, including intramedullary nailing, internal fixation, and external fixation, are complicated by prolonged immobility, malunion, and nonunion. Furthermore, fixation increases the complexity of subsequent arthroplasty. Primary total knee arthroplasty (TKA) is a rarely used treatment for acute DFF but may be of benefit in select patients...
May 2017: American Journal of Orthopedics
https://www.readbyqxmd.com/read/28663403/-modern-distal-femoral-locking-plates-allow-safe-early-weight-bearing-with-a-high-rate-of-union-and-low-rate-of-failure-five-year-experience-from-a-united-kingdom-major-trauma-centre
#8
W E C Poole, D G G Wilson, H C Guthrie, S F Bellringer, R Freeman, E Guryel, S G Nicol
AIMS: Fractures of the distal femur can be challenging to manage and are on the increase in the elderly osteoporotic population. Management with casting or bracing can unacceptably limit a patient's ability to bear weight, but historically, operative fixation has been associated with a high rate of re-operation. In this study, we describe the outcomes of fixation using modern implants within a strategy of early return to function. PATIENTS AND METHODS: All patients treated at our centre with lateral distal femoral locking plates (LDFLP) between 2009 and 2014 were identified...
July 2017: Bone & Joint Journal
https://www.readbyqxmd.com/read/28660328/radiological-study-of-the-secondary-reduction-effect-of-early-functional-exercise-on-displaced-intra-articular-calcaneal-fractures-after-internal-compression-fixation
#9
Wei Chen, Bo Liu, Hongzhi Lv, Yanling Su, Xiao Chen, Yanbin Zhu, Chenguang Du, Xiaolin Zhang, Yingze Zhang
PURPOSE: Early post-operative exercise and weight-bearing activities are found to improve the functional recovery of patients with displaced intra-articular calcaneal fractures (DIACFs). We hypothesized that early functional exercise after surgery might have a secondary reduction effect on the subtalar joint, in particular the smaller fracture fragments that were not fixed firmly. A prospective study was conducted to verify this hypothesis. METHODS: From December 2012 to September 2013, patients with unilateral DIACFs were enrolled and received a treatment consisting of percutaneous leverage and minimally invasive fixation...
June 28, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/28657574/megaprosthesis-of-the-knee-in-tumor-and-revision-surgery
#10
E Pala, G Trovarelli, A Angelini, M Maraldi, A Berizzi, Pietro Ruggieri
The introduction of multidisciplinary approach with chemo and radiotherapy, the advances in surgical and the improvements of diagnostic techniques allowed limb salvage surgery in most cases of bone sarcomas instead of amputation. Modular megaprostheses are the most common method of reconstruction after segmental resection of the long bones in the extremities for their availability, immediate fixation, early weight bearing, good function. Despite the advances in materials and implant designs, these systems have an high incidence of complications...
June 7, 2017: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/28642979/-medial-opening-wedge-high-tibial-osteotomy
#11
REVIEW
P Niemeyer, A Stöhr, M Köhne, A Hochrein
OBJECTIVE: Reduction of the load to the medial compartment in patients with medial knee osteoarthritis and varus malalignment. Unloading of the posterolateral complex in varus deformity with complex ligamentous laxity. INDICATIONS: Medial knee osteoarthritis and varus malalignment with largely intact lateral and patellofemoral joint aspect. Complex ligament insufficiency combined with varus deformity. CONTRAINDICATIONS: Substantially impaired range of motion...
June 22, 2017: Operative Orthopädie und Traumatologie
https://www.readbyqxmd.com/read/28630716/femoral-neck-fractures-as-a-complication-of-hip-arthroscopy-a-systematic-review
#12
REVIEW
Nolan S Horner, Khanduja Vikas, Austin E MacDonald, Jan-Hendrik Naendrup, Nicole Simunovic, Olufemi R Ayeni
The purpose of this study was to identify the causes and risk factors for hip fractures, a rare but devastating complication, following hip arthroscopy. The electronic databases MEDLINE, EMBASE and PubMed were searched and screened in duplicate for relevant clinical and basic sciences studies and pertinent data was abstracted and analysed in Microsoft Excel. Nineteen studies (12 clinical studies and seven biomechanical studies) with a total of 31 392 patients experiencing 43 hip fractures (0.1% of patients) met the inclusion criteria for this systematic review...
January 2017: Journal of Hip Preservation Surgery
https://www.readbyqxmd.com/read/28620575/osteoporosis-management-in-ankylosing-spondylitis
#13
Alicia M Hinze, Grant H Louie
Low bone mineral density (BMD) is increasingly recognized as a common comorbid condition in ankylosing spondylitis (AS). As low BMD increases fracture risk, it is important to identify and treat low BMD in patients with AS who have been shown to be at increased risk for fractures above the population normal. Since low BMD occurs early in disease, we screen during the first year of diagnosis with dual energy x-ray absorptiometry (DXA). If patients are found to have osteoporosis by T-score of less than -2.5 or if their Z-score on DXA is more than two standard deviations below the mean, we initiate therapy with bisphosphonates in males and in females who are not planning any future pregnancies...
December 2016: Current Treatment Options in Rheumatology
https://www.readbyqxmd.com/read/28570307/early-mobilization-in-lower-extremity-frostbite-injury-preliminary-experience-at-a-single-burn-center
#14
Michelle Dole, Frederick W Endorf, Jon Gayken, Ryan Fey, Rachel M Nygaard
Cold exposure that leads to frostbite puts patients at high risk for extremity amputations. Recent treatment advances, such as thrombolytic administration, have decreased amputation rates. However, little is known about patient outcomes with early mobilization of affected limbs. A retrospective review of 41 patients admitted for lower extremity frostbite was performed at an urban hospital burn unit. All patients received the institution's standard frostbite treatment protocol. The study group was allowed to bear weight within 72 hours, while the control group was immobilized beyond this time frame...
May 26, 2017: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/28567153/comparison-of-post-operative-muscular-strength-between-gamma-nailing-and-hemiarthroplasty-system-in-femoral-intertrochanteric-fractures
#15
Mitsuaki Noda, Yasuhiro Saegusa, Masayasu Takahashi, Chisa Noguchi, Chihiro Yoshikawa, Hiroshi Mikami, Akira Gotouda
BACKGROUND: The current study focuses on the comparison of postoperative muscular strength around the hip joint of patients with femoral intertrochanteric fractures treated either by cephalo-medullary (CM) nailing or a new bipolar hip prosthesis (BHP), an especially attached device to secure displaced greater trochanteric fragment. METHODS: Twenty patients treated with CM nailing were age- and sex- matched with a control group of 20 patients treated with BHP. Maximum isometric forces at the bilateral hip joint were measured during the follow up period...
2017: Open Orthopaedics Journal
https://www.readbyqxmd.com/read/28537541/-earlier-weight-bearing-mobilisation-after-fracture-fixation
#16
P R G Brink, E J M M Verleisdonk, T J Blokhuis
Almost all the literature dictates a period of non-weight-bearing after surgical treatment of articular and peri-articular fractures of the pelvis and lower extremities. This is followed by partial weight-bearing which is based on the number of weeks after surgery. However, none of these recommendations are based on evidence. When taking muscle force and gravity into account, non-weight-bearing is actually impossible. In addition, lack of patient compliance, lack of muscle force in the elderly and four-fold energy expenditure make it almost impossible to ensure that patients will adhere to their surgeon's restrictions...
2017: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/28526167/significance-of-body-weight-change-during-fertility-sparing-progestin-therapy-in-young-women-with-early-endometrial-cancer
#17
MULTICENTER STUDY
Jeong-Yeol Park, Seok Ju Seong, Tae-Jin Kim, Jae Weon Kim, Duk-Soo Bae, Joo-Hyun Nam
OBJECTIVE: To evaluate the influence of body weight change during fertility-sparing progestin therapy on oncologic and reproductive outcomes in young women with early-stage endometrial cancer who did not complete child bearing. METHODS: This multicenter, retrospective study included 154 young patients with well-differentiated, endometrium-confined endometrioid endometrial adenocarcinoma on magnetic resonance imaging who received fertility-sparing progestin therapy...
July 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/28514822/-cardiovascular-effects-of-antidiabetic-therapies
#18
Katharina Laubner, Jochen Seufert
Type 2- diabetes mellitus (T2DM) represents a major risk factor for cardiovascular complications and mortality. Strict glucose control in the early course of the disease prevents cardiovascular complications only in the long run. Non-medical therapies (diet, exercise, body weight reduction) bear little evidence for positive cardiovascular effects.Bariatric surgery is not number one choice in therapy of T2DM. Metformin seems to provide positive cardiovascular effects. Insulin seems to be cardiovascular neutral, as well as the DPP4-inhibitors Saxagliptin, Sitagliptin and Alogliptin...
May 2017: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/28512850/in-situ-handheld-3d-bioprinting-for-cartilage-regeneration
#19
Claudia Di Bella, Serena Duchi, Cathal D O'Connell, Romane Blanchard, Cheryl Augustine, Zhilian Yue, Fletcher Thompson, Christopher Richards, Stephen Beirne, Carmine Onofrillo, Sebastien H Bauquier, Stewart D Ryan, Peter Pivonka, Gordon G Wallace, Peter F Choong
Articular cartilage injuries experienced at an early age can lead to the development of osteoarthritis later in life. In situ 3D printing is an exciting and innovative bio-fabrication technology that enables the surgeon to deliver tissue- engineering techniques at the time and location of need. We have created a hand- held 3D printing device (Biopen) that allows the simultaneous co-axial extrusion of bioscaffold and cultured cells directly into the cartilage defect in vivo in a single session surgery. This pilot study assesses the ability of the Biopen to repair a full thickness chondral defect and the early outcomes in cartilage regeneration, and compares these results to other treatments in a large animal model...
May 17, 2017: Journal of Tissue Engineering and Regenerative Medicine
https://www.readbyqxmd.com/read/28505355/uncovering-the-neuroanatomical-correlates-of-cognitive-affective-and-conative-theory-of-mind-in-pediatric-traumatic-brain-injury-a-neural-systems-perspective
#20
Nicholas P Ryan, Cathy Catroppa, Richard Beare, Timothy J Silk, Stephen J Hearps, Miriam H Beauchamp, Keith Owen Yeates, Vicki A Anderson
Deficits in Theory of Mind (ToM) are common after neurological insult acquired in the first and second decade of life, however the contribution of large-scale neural networks to ToM deficits in children with brain injury is unclear. Using pediatric traumatic brain injury (TBI) as a model, this study investigated the sub-acute effect of brain injury on gray-matter volume of three large-scale, domain-general brain networks (the Default Mode Network, DMN; the Central Executive Network, CEN; and the Salience Network, SN), as well as two domain-specific neural networks implicated in social-affective processes (the Cerebro-Cerebellar Mentalizing Network, CCMN, and the Mirror Neuron/Empathy Network, MNEN)...
May 15, 2017: Social Cognitive and Affective Neuroscience
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