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https://www.readbyqxmd.com/read/28097423/rehabilitation-of-achilles-tendon-ruptures-is-early-functional-rehabilitation-daily-routine
#1
B Frankewycz, W Krutsch, J Weber, A Ernstberger, M Nerlich, Christian G Pfeifer
INTRODUCTION: Ruptures of the Achilles tendon are the most common tendon injuries of the lower extremities. Besides the initial operative or non-operative treatment, rehabilitation of patients plays a crucial role for tendon healing and long-term outcome. As only limited evidence is available for optimized rehabilitation regimen and guidelines for the initial (e.g., first 6 weeks) rehabilitation are limited, this study investigated the current rehabilitation concepts after Achilles tendon rupture...
January 17, 2017: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/28090441/principal-component-analysis-t1%C3%AF-voxel-based-relaxometry-of-the-articular-cartilage-a-comparison-of-biochemical-patterns-in-osteoarthritis-and-anterior-cruciate-ligament-subjects
#2
Valentina Pedoia, Colin Russell, Allison Randolph, Xiaojuan Li, Sharmila Majumdar
BACKGROUND: Quantitative MR, including T1ρ mapping, has been extensively used to probe early biochemical changes in knee articular cartilage of subjects with osteoarthritis (OA) and others at risk for cartilage degeneration, such as those with anterior cruciate ligament (ACL) injury and reconstruction. However, limited studies have been performed aimed to assess the spatial location and patterns of T1ρ. In this study we used a novel voxel-based relaxometry (VBR) technique coupled with principal component analysis (PCA) to extract relevant features so as to describe regional patterns and to investigate their similarities and differences in T1ρ maps in subjects with OA and subjects six months after ACL reconstruction (ACLR)...
December 2016: Quantitative Imaging in Medicine and Surgery
https://www.readbyqxmd.com/read/28051969/effects-of-adding-neuromuscular-electrical-stimulation-to-traditional-military-amputee-rehabilitation
#3
Laura A Talbot, Emily Brede, E Jeffrey Metter
BACKGROUND: Traumatic transtibial amputations lead to an early decline in the use and weight bearing of the residual limb. These changes result in progressive quadriceps muscle atrophy with strength loss that affects standing and walking. Neuromuscular electrical stimulation (NMES) may be useful as an adjunct to amputee prosthetic rehabilitation to maintain quadriceps muscle strength and mass. The objective of this pilot study was to compare the effects of a home-based NMES rehabilitation program plus the traditional military amputee rehabilitation program (TMARP) to the effects of TMARP alone on quadriceps muscle strength, functional mobility, and pain in military service members after a combat-related lower extremity amputation...
January 2017: Military Medicine
https://www.readbyqxmd.com/read/28038362/brain-connectivity-networks-and-longitudinal-trajectories-of-depression-symptoms-in-adolescence
#4
Rachel Ellis, Marc L Seal, Christopher Adamson, Richard Beare, Julian G Simmons, Sarah Whittle, Nicholas B Allen
High levels of depression during adolescence may contribute to the risk for future depression later in life. This study examined the relationship between the developmental timing of depressive symptoms, and brain structural outcomes in late adolescence. In a prior work, we examined longitudinal trajectories of depressive symptoms in 243 adolescents (121 males and 122 females), and identified four subgroups: a normative group with stable low levels of depression, two groups with declining symptoms, and one group with increasing symptoms...
December 21, 2016: Psychiatry Research
https://www.readbyqxmd.com/read/28027735/comparison-of-t2-relaxation-times-of-articular-cartilage-of-the-knee-in-elite-professional-football-players-and-age-and-bmi-matched-amateur-athletes
#5
C Behzadi, G H Welsch, A Laqmani, F O Henes, M G Kaul, G Schoen, G Adam, M Regier
OBJECTIVE: Recent investigation has underlined the potential of quantitative MR imaging to be used as a complementary tool for the diagnosis of cartilage degeneration at an early state. The presented study analyses T2* relaxation times of articular cartilage of the knee in professional athletes and compares the results to age- and BMI (Body Mass Index)-matched healthy amateur athletes. MATERIALS AND METHODS: 22 professional football players and 22 age- and BMI-matched individuals were underwent knee Magnetic Resonance Imaging (MRI) at 3T including qualitative and quantitative analysis...
January 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28018090/natural-tibialization-of-fibula-in-non-union-tibia-two-cases
#6
Vinay Prabhat, Gauresh S Vargaonkar, Sunil R Mallojwar, Ramesh Kumar
BACKGROUND: Non-union of tibia is known to be a common complication after fracture both bones of leg treated conservatively. During the course of natural healing, fibula usually unites early as it had more soft tissue attachment and vascular supply. Due to early union of fibula and absence of axial force across the tibia, it undergoes non-union. CASE CHARACTERISTICS: Two cases, a 32-year-old male and 65-year-old female treated conservatively for fracture both bones of leg long years back, presented to us with mild calf pain on and off...
October 2016: Journal of Clinical Orthopaedics and Trauma
https://www.readbyqxmd.com/read/28017952/-effect-of-exercise-and-sports-activity-on-bone-health-during-the-period-of-adolescence-to-young-adulthood
#7
Takeru Kato
Physical activity may play an important role in maximizing bone mass during adolescence to young adulthood and may have long-lasting benefits on bone health. Because peak bone mass is thought to be attained by the end of the third decade, the early adult years may be the final opportunity for its augmentation. High-impact weight-bearing exercise during youth may provide lifelong benefits in terms of bone mineral content, structure and strength, and consequently reduce fracture risk. Weight-bearing exercise in youth affects bone, and these effects may be preserved as BMC, geometric and structural advantages even after 40 years...
2017: Clinical Calcium
https://www.readbyqxmd.com/read/28009137/osteonecrosis-as-a-complication-in-pediatric-patients-with-acute-lymphoblastic-leukemia
#8
Ilaria Riccio, Elvira Pota, Marco Marcarelli, Maria Carmen Affinita, Daniela Di Pinto, Cristiana Indolfi, Nicola Del Regno, Marco Esposito
Osteonecrosis is a significant adverse effect of treatment administered to children suffering from acute lymphoblastic leukemia (ALL) that may have a negative effect on the quality of life. The purpose of this study is to evaluate the rate of secondary vascular osteonecrosis (ON) in a population of pediatric patients with ALL treated with corticosteroids and cytostatic agents. A retrospective analysis of prospectively collected data of the medical records of 328 patients with ALL identified 4 cases with ON, corresponding to 1...
November 28, 2016: La Pediatria Medica e Chirurgica: Medical and Surgical Pediatrics
https://www.readbyqxmd.com/read/28002357/pediatric-sacroiliitis-clinical-and-microbiologic-differences-between-infants-and-children-adolescents
#9
Ambra Donzelli, Eleftheria Samara, Vassiliki Spyropoulou, Céline Juchler, Dimitri Ceroni
BACKGROUND: The aim of this study was to improve knowledge of pediatric pyogenic sacroiliitis (PSI) in the pediatric population based on a consecutive case series. METHOD: We conducted a single-center cross-sectional study on 16 patients admitted to the emergency department of our Hospital between January 1990 and December 2015 with a confirmed diagnosis of PSI. The patients were divided into 2 groups by age: infants (6 months - 4 years) and children-adolescents (4-16 years)...
December 19, 2016: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/27987018/-osteosynthesis-of-distal-fibular-fractures-with-illuminoss-video-article
#10
M Zyskowski, M Crönlein, E Heidt, P Biberthaler, C Kirchhoff
OBJECTIVE: The aim was minimally invasive osteosynthesis of a distal fibular fracture under the premises of poor soft tissue conditions and existing chronic comorbidities to enable rapid recovery and to reduce soft tissue stress in order to avoid postoperative infections and achieve early weight bearing. INDICATIONS: This involved a distal fibula fracture, classified as 44 B1.1, B1.2, B1.3 according to the working group for osteosynthesis (AO) or a B fracture after Danis and Weber with indications for surgery (cortical disruption and shaft offset > 5 mm), age > 65 years, poor soft tissue conditions and a Charlson score ≥ 1...
January 2017: Der Unfallchirurg
https://www.readbyqxmd.com/read/27928730/guided-growth-may-not-be-the-best-option-for-knee-valgus-deformity-in-adolescent-patients-with-morquio-a
#11
D Colmenares-Bonilla, M Vasconcelos-Martinez, J Guerra-Jasso, L Ocampo-Perez
INTRODUCTION: Valgus deformity in knees is a common concern in Morquio-A patients, preceding premature arthrosis and pain leading to walking disability and loss of ambulatory status. Treatment alternative is the guided growth, but this is sometimes not applied on time. Due to short height reached on these patients, not all will benefit from guided growth surgery. PURPOSE: The purpose of this study is to describe early results of physeal osteotomy for acute valgus correction in adolescent patients and those almost at height peak to achieve alignment...
December 7, 2016: Musculoskeletal Surgery
https://www.readbyqxmd.com/read/27921119/-distal-humerus-fracture-extensile-approaches
#12
F J P Beeres, F Oehme, R Babst
The majority of dislocated, intra-articular fractures are treated with an open reduction and internal fixation. In this paper we describe a variety of dorsal approaches to the distal humerus. Beside the dorsal approach through an olecranon osteotomy we also discuss the alternative dorsal approaches without osteotomy and their advantages and drawbacks. Moreover we discuss the preoperative planning and operative procedure. Early functional rehabilitation, without weight bearing, is important to achieve an optimal outcome...
December 5, 2016: Operative Orthopädie und Traumatologie
https://www.readbyqxmd.com/read/27911930/the-therapeutic-response-of-gastrointestinal-stromal-tumors-to-imatinib-treatment-assessed-by-intravoxel-incoherent-motion-diffusion-weighted-magnetic-resonance-imaging-with-histopathological-correlation
#13
Feng Pan, Jie Den, Chunfang Zhang, He Wang, Jin Cheng, Weizhen Wu, Nan Hong, Yi Wang
PURPOSE: To exploit the intravoxel incoherent motion (IVIM) diffusion-weighted (DW) MRI when evaluating the therapeutic response of gastrointestinal stromal tumors (GIST) to Imatinib in a mouse model. MATERIALS AND METHODS: Mice with xenografts bearing cells from the GIST-T1 cell line were randomly divided into a treated group receiving Imatinib and a control group. DWMRI scans with 14 b-values (0-1500 s/mm2) were performed before and after treatment (days 1, 3 and 7)...
2016: PloS One
https://www.readbyqxmd.com/read/27909665/autologous-osteophyte-grafting-for-open-wedge-high-tibial-osteotomy
#14
Takenori Akiyama, Ken Okazaki, Taro Mawatari, Satoshi Ikemura, Shunsuke Nakamura
Osteophytes are physiological bony outgrowths that develop at the margins of the articular surfaces during the progression of osteoarthritis; they are associated with active endochondral bone formation processes and expressions of various growth factors. We believe they could be a source of bone grafts as a result of a potentially strong osteoinductive effect. Moreover, osteophytes can be easily harvested by arthroscopy in patients undergoing open-wedge high tibial osteotomy (OW-HTO) for medial unicompartmental knee osteoarthritis...
October 2016: Arthroscopy Techniques
https://www.readbyqxmd.com/read/27906072/actrii-blockade-protects-mice-from-cancer-cachexia-and-prolongs-survival-in-the-presence-of-anti-cancer-treatments
#15
Shinji Hatakeyama, Serge Summermatter, Marie Jourdain, Stefan Melly, Giulia C Minetti, Estelle Lach-Trifilieff
BACKGROUND: Cachexia affects the majority of patients with advanced cancer and is associated with reduced treatment tolerance, response to therapy, quality of life, and life expectancy. Cachectic patients with advanced cancer often receive anti-cancer therapies against their specific cancer type as a standard of care, and whether specific ActRII inhibition is efficacious when combined with anti-cancer agents has not been elucidated yet. METHODS: In this study, we evaluated interactions between ActRII blockade and anti-cancer agents in CT-26 mouse colon cancer-induced cachexia model...
July 26, 2016: Skeletal Muscle
https://www.readbyqxmd.com/read/27900190/prospective-12-month-functional-and-vocational-outcomes-of-hip-arthroscopy-for-femoroacetabular-impingement-as-part-of-an-evidence-based-hip-pain-rehabilitation-pathway-in-an-active-military-population
#16
A N Bennett, J Nixon, A Roberts, R Barker-Davies, R Villar, J M Houghton
BACKGROUND: Femoroacetabular impingement (FAI) is common with an estimated prevalence of 10-15% among young active individuals. The natural history of the disorder is progression to early osteoarthritis. Hip arthroscopy is recommended if conservative treatments fail; however, outcomes are unclear, particularly in highly active populations. AIM: To evaluate the functional and vocational outcome of hip arthroscopy, as part of an evidence-based rehabilitation hip pain pathway, for the treatment of FAI in an active military population...
2016: BMJ Open Sport & Exercise Medicine
https://www.readbyqxmd.com/read/27888790/complication-assessment-and-prevention-strategies-using-midfoot-fusion-bolt-for-medial-column-stabilization-in-charcot-s-osteoarthropathy
#17
Alexander T Mehlhorn, Markus Walther, Niklas Iblher, Norbert P Südkamp, Hagen Schmal
In Charcot's osteoarthropathy stabilization of the medial column of the foot was introduced in order to establish a stable foot and reduce the risk for amputation. This study was performed to analyze postoperative complications, define risk factors for those and develop strategies for prevention. Since bolt dislocation takes place frequently, it was aimed to predict an appropriate time point for bolt removal under the condition that osseous healing has occurred. Fourteen consecutive patients with neuroosteoarthropathy of the foot and arch collapse were treated with open reduction and stabilization using midfoot fusion bolt and lateral lag screws...
December 2016: Foot
https://www.readbyqxmd.com/read/27886836/ulnar-neuropathy-in-cyclists
#18
REVIEW
Jacob W Brubacher, Fraser J Leversedge
The form and function of the cyclist exposes the ulnar nerve to both traction and compressive forces at both the elbow and wrist. Prevention of ulnar neuropathy and treatment of early symptoms include bike fitting, avoidance of excessive or prolonged weight-bearing through the hands, and the use of padded gloves. For persisting or progressive symptoms, a thorough history and physical examination is essential to confirm the diagnosis and to rule out other sites of nerve compression. The majority of compression neuropathies in cyclists resolve after appropriate rest and conservative treatment; however, should symptoms persist, nerve decompression may be indicated...
February 2017: Hand Clinics
https://www.readbyqxmd.com/read/27885384/use-of-the-arthroereisis-screw-with-tendoscopic-delivered-platelet-rich-plasma-for-early-stage-adult-acquired-flatfoot-deformity
#19
Youichi Yasui, Ichiro Tonogai, Andrew J Rosenbaum, David M Moore, Masato Takao, Hirotaka Kawano, John G Kennedy
PURPOSE: Early stage adult acquired flatfoot deformity (AAFD) is traditionally treated with osteotomy and tendon transfer. Despite a high success rate, the long recovery time and associated morbidity are not sufficient. This study aims to evaluate the functional and radiological outcomes following the use of the arthroereisis screw with tendoscopic delivered PRP for early stage AAFD. METHODS: Patients with stage IIa AAFD who underwent the use of the arthroereisis screw with tendoscopic delivered PRP with a minimum follow-up time of 24 months were retrospectively evaluated...
November 24, 2016: International Orthopaedics
https://www.readbyqxmd.com/read/27883222/alcohol-misuse-and-co-occurring-mental-disorders-among-new-soldiers-in-the-u-s-army
#20
Murray B Stein, Laura Campbell-Sills, Joel Gelernter, Feng He, Steven G Heeringa, Matthew K Nock, Nancy A Sampson, Xiaoying Sun, Sonia Jain, Ronald C Kessler, Robert J Ursano
BACKGROUND: Problem drinking that predates enlistment into military service may contribute to the overall burden of alcohol misuse in the Armed Forces; however, evidence bearing on this issue is limited. This study examines prevalence and correlates of alcohol misuse among new U.S. Army soldiers. METHODS: Cross-sectional survey data were collected from soldiers reporting for basic combat training. The survey retrospectively assessed lifetime alcohol consumption and substance abuse/dependence, enabling estimation of the prevalence of lifetime binge drinking and heavy drinking in a sample of 30,583 soldiers and of probable alcohol use disorder (AUD) among 26,754 soldiers with no/minimal lifetime use of other drugs...
January 2017: Alcoholism, Clinical and Experimental Research
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