Katya C Rocha, Cinthia Pinhal, Sônia Cavalcanti, Monica S M Vidal, Matheus Toscano, Dewton Moraes-Vasconcelos, Alberto J S Duarte, Fernando L A Fonseca, Luiz Carlos de Abreu, Vitor E Valenti, Anete S G Grumach
BACKGROUND: Cryptococcus neoformans causes meningitis and disseminated infection in healthy individuals, but more commonly in hosts with defective immune responses. Cell-mediated immunity is an important component of the immune response to a great variety of infections, including yeast infections. We aimed to evaluate a specific lymphocyte transformation assay to Cryptococcus neoformans in order to identify immunodeficiency associated to neurocryptococcosis (NCC) as primary cause of the mycosis...
October 30, 2012: BMC Infectious Diseases