keyword
https://read.qxmd.com/read/38532750/noninvoluting-congenital-hemangiomas-with-hypovolemic-shock-anemia-and-prolonged-jaundice-in-a-neonate-a-case-report
#1
Mansoor Aslamzai, Turyalai Hakimi, Mesbahullah Mushoud, Abdul Hakim Mukhlis
Noninvoluting congenital hemangioma is an extremely rare congenital anomaly in newborn babies and may complicate life-threatening events, including hemorrhage. We present a very rare case of noninvoluting congenital hemangiomas in an Asian and Afghan six-day-old girl that was detected at birth. The noninvoluting congenital hemangiomas were accompanied by hypovolemic shock, anemia, and prolonged jaundice during the first two weeks of life. These diseases were diagnosed by medical history, physical examination, blood analysis, and doppler ultrasonography of the skin lesions...
March 2024: Oxford Medical Case Reports
https://read.qxmd.com/read/38524344/anatomical-outcome-of-laser-treatment-alone-in-aggressive-retinopathy-of-prematurity
#2
JOURNAL ARTICLE
Anamika Dwivedi, Deepak Dwivedi, Sujata Lakhtakia, Chalisgaonkar Charudutt
PURPOSE: The purpose is to study the anatomical outcome of eyes in aggressive retinopathy of prematurity (AROP), treated with laser photocoagulation alone and to evaluate factors affecting outcomes. METHODS: Records of consecutive babies diagnosed with AROP, undergoing laser photocoagulation treatment in rural tertiary care centers from October 2016 to January 2021 were reviewed retrospectively. Anatomical outcome at 6 months follow-up was grouped as good in eyes with complete regression and poor in those who developed retinal detachment (stage IV a, IV b, and V)...
2024: Oman Journal of Ophthalmology
https://read.qxmd.com/read/38518030/the-evolution-of-sepsis-publications-and-global-productivity-a-bibliometric-analysis-between-1980-and-2020
#3
JOURNAL ARTICLE
Arzu Akdagli Ekici, Alperen Kisa, Semin Önder Turhan
The literature study was conducted by using the Web of Science (WoS) database, employing bibliometric analysis to examine all papers released from 1980 to 2020. The search was performed using the terms "sepsis, septicemia, septic shock" specifically within the titles of the publications. The findings of the literature research revealed a total of 51,725 articles. Out of the total number of publications, 26,896 articles were identified, accounting for 51.9% of the total. The bibliometric study revealed that the United States had the largest number of papers (8693), followed by China (2807), Germany (2299), France (1606), and the United Kingdom (1932)...
March 22, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38506871/-non-ige-mediated-food-allergy
#4
JOURNAL ARTICLE
María Isabel Rojo Gutiérrez, Diego Ballesteros González, Ana Karen Ortiz Durán
Food allergy is an immune response to proteins in food. It usually affects 8% of children and 2% of adults in Western countries. Non-IgE-mediated food allergy mainly affects the gastrointestinal tract. Gastrointestinal food allergies are classified, by their underlying pathogenesis, as: IgE-mediated, non-IgE-mediated, or mixed. The symptoms of patients with food protein-induced allergic proctocolitis originate from local inflammation of the distal colon, which causes hematochezia in neonates. It can affect the entire gastrointestinal tract and cause symptoms of intractable emesis, with subsequent metabolic disorders and hypovolemic shock...
December 31, 2023: Revista Alergia Mexico: Organo Oficial de la Sociedad Mexicana de Alergia e Inmunología, A.C
https://read.qxmd.com/read/38491718/tranexamic-acid-versus-oxytocin-for-primary-postpartum-haemorrhage-in-the-out-of-hospital-setting-a-systematic-review-with-implications-for-rural-practice
#5
REVIEW
Megan De Silva, Gabrielle Mizzi, Emily Potts, Jayden Webb, Elizabeth Thyer, Navindhra Naidoo
INTRODUCTION: Primary postpartum haemorrhage causes approximately 25% of global maternal deaths and accounts for significant maternal morbidity. While high certainty evidence demonstrates that tranexamic acid reduces comparative blood loss in postpartum haemorrhage in hospital settings, limited data exist on the specific pharmacological management of this condition in out-of-hospital settings, and the implications for rural communities. OBJECTIVE: To determine the efficacy of oxytocin compared to tranexamic acid in women suffering postpartum haemorrhage in the out-of-hospital environment...
March 15, 2024: Australian Journal of Rural Health
https://read.qxmd.com/read/38490704/congenital-brain-tumour-in-a-neonate-a-therapeutic-challenge
#6
JOURNAL ARTICLE
Praneetha Mude, Monalisa Pradhan, Anuj Tiwari, Tapas Kanti Parida, Manoj Kumar Nayak, Arun Kumar Sekar, Suvendu Purkait, Usha Devi
A term neonate with history of ventriculomegaly in the fetal period was diagnosed with a central nervous system tumour after radiological investigations. It was confirmed as an immature teratoma after histopathological examination. He underwent left frontal craniotomy with tumour excision. Intraoperatively, massive haemorrhage (venous bleed) occurred due to the high vascularity of the tumour and led to haemodynamic instability. A massive transfusion protocol was initiated. Despite multiple transfusions and shock management, he succumbed at 2 weeks of life...
March 15, 2024: BMJ Case Reports
https://read.qxmd.com/read/38484464/bilateral-adrenal-hemorrhage-and-severe-anemia-in-a-neonate
#7
JOURNAL ARTICLE
Christina Lee, Leah Hirschman, Teresa York, Paula Newton
SUMMARY: Neonatal adrenal hemorrhage (NAH) occurs in up to 3% of infants and is the most common adrenal mass in newborns. The most common presentation of NAH is an asymptomatic palpable flank mass which resolves over time without intervention. In rare cases, NAH can present as hemorrhage, shock, or adrenal insufficiency. This case describes a preterm infant born with severe anemia in the setting of bilateral adrenal hemorrhages with resulting adrenal insufficiency. The infant was successfully treated with blood transfusions and steroids...
January 1, 2024: Endocrinology, Diabetes & Metabolism Case Reports
https://read.qxmd.com/read/38457556/late-onset-neonatal-sepsis-can-plasma-gelsolin-be-a-promising-diagnostic-marker
#8
JOURNAL ARTICLE
Wesam A Mokhtar, Laila M Sherief, Naglaa M Kamal, Azza O ElSheikh, Farida H Omran, Ahmed Abdulsaboor, Maha M H Sakr, Shreif El Gebally, Mohamed M M Shehab, Jaber Alfaifi, Reem Turkistani, Futun Aljuaid, Mohammed A M Oshi, Fouad B A Elbekoushi, Ghada A Mokhtar
Plasma gelsolin (pGSN) correlates with clinical improvement in septic patients. We aimed to investigate pGSN levels as a diagnostic and prognostic marker of neonatal late-onset-sepsis (LOS). A case-control study was done on 184 neonates (92 with LOS and 92 controls). All participants were subjected to detailed history taking, full clinical evaluation, sepsis workup, and pGSN enzyme-linked immunosorbent-assay measurement. We detected significantly lower pGSN level among cases compared to controls (90.63 ± 20...
March 8, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38440333/factors-in-the-neonatal-period-associated-with-pulmonary-hypertension-at-28%C3%A2-days-of-life-in-broncho-pulmonary-dysplasia
#9
JOURNAL ARTICLE
Nguyen Thi Hai Anh, Tran Minh Dien, Le Thi Ha, Pham Thao Nguyen, Dang Thi Hai Van
Objectives. To identify factors associated with pulmonary hypertension (PH) at 28 days of life in preterm infants with bronchopulmonary dysplasia (BPD). Methods . This observational study included 128 premature infants with BPD between January 2022 and February 2023 from the neonatal intensive care unit of Vietnam National Children's Hospital. Results . PH was observed using echocardiography in 29 patients (22.66%). The prevalence of severe BPD in the PH group (62.07%) was significantly higher than that in the non-PH group (18...
2024: Global Pediatric Health
https://read.qxmd.com/read/38432651/a-career-in-solving-clinical-pathological-conundrums-heyde-syndrome-anti-platelet-factor-4-disorders-and-microvascular-limb-ischemic-necrosis
#10
REVIEW
Theodore E Warkentin
Hematology is a clinical specialty with strong roots in the laboratory; accordingly, the lab can help solve perplexing clinical problems. This review highlights clinical-pathological conundrums addressed during my 35-year hematology career at McMaster University. Heyde syndrome is the association between aortic stenosis and bleeding gastrointestinal (GI) angiodysplasia where the bleeding is usually cured by aortic valve replacement; the chance reading of a neonatal study showing reversible deficiency of high-molecular-weight (HMW) multimers of von Willebrand factor (vWF) following surgical correction of congenital heart disease provided the key insight that a subtle deficiency of HMW multimers of vWF explains Heyde syndrome...
March 3, 2024: International Journal of Laboratory Hematology
https://read.qxmd.com/read/38371484/knowledge-practice-and-associated-factors-towards-supplemental-oxygen-therapy-among-nurses-working-in-neonatal-intensive-care-units-in-public-hospitals-of-addis-ababa-ethiopia-2022-a-cross-sectional-study
#11
JOURNAL ARTICLE
Assefa Dansa, Debela Gela, Mekonen Adimasu Kebede
PURPOSE: Proper administration of oxygen therapy for hospitalized newborns is undoubtedly essential. World Health Organization estimates that approximately 1.4 million deaths worldwide each year are due to inappropriate administration of oxygen, but its administration in clinical practice is usually inappropriate due to lack of knowledge and practice. Therefore, the aim of this study was to determine the level of knowledge, practice and associated factors related to supplemental oxygen therapy among nurses working in neonatal intensive care units...
2024: Pediatric Health, Medicine and Therapeutics
https://read.qxmd.com/read/38363932/diagnostic-and-prognostic-value-of-pct-and-rdw-in-premature-infants-with-septicemia
#12
JOURNAL ARTICLE
Huafen Xu, Dong Ca, Lixia Zhou
It aims to study the diagnostic effect of procalcitonin (PCT) and red blood cell distribution width (RDW) in premature septicemia (PS), and to analyze the prognostic evaluation value of PCT and RDW in PS. Ninety eight septicemia premature infants (SPI) who visited the neonatal intensive care unit of our hospital from June 2019 to July 2021 were selected and met the criteria. Based on the patient's condition and the neonatal shock score, they were separated into a severe group (SG) and a mild group (MG). There were 43 children and 55 children in the 2 groups, respectively...
February 16, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38356998/recent-cluster-of-neonatal-enteroviral-myocarditis-cases-in-the-united-kingdom-of-great-britain-and-northern-ireland-current-scenario-and-counteracting-prospects
#13
JOURNAL ARTICLE
Amrita Pattanaik, Sushma Bhandarkar B, Sreelakshmi V, Chiranjay Mukhopadhyay
OBJECTIVES: Neonatal myocarditis is a rare but life-threatening complication of enterovirus infection that presents like bacterial sepsis. OUTBREAK: A sudden upsurge in cases of neonatal enteroviral myocarditis, reported from South West England and South Wales between June 2022 and April 2023 has alerted health agencies to bring in counteracting measures. IMPACT: In view of this outbreak situation, the World Health Organisation advisory has urged clinicians seeing neonates and infants with shock may consider myocarditis as a differential diagnosis and test for enteroviruses...
March 2024: IJID Reg
https://read.qxmd.com/read/38355477/intravenous-lipid-emulsion-for-local-anaesthetic-systemic-toxicity-in-pregnant-women-a-scoping-review
#14
REVIEW
Makoto Tsuji, Masafumi Nii, Marie Furuta, Shinji Baba, Takahide Maenaka, Shigetaka Matsunaga, Hiroaki Tanaka, Atsushi Sakurai
BACKGROUND: Local anaesthetic systemic toxicity (LAST) is a rare but life-threatening complication that can occur after local anaesthetic administration. Various clinical guidelines recommend an intravenous lipid emulsion as a treatment for local anaesthetic-induced cardiac arrest. However, its therapeutic application in pregnant patients has not yet been established. This scoping review aims to systematically identify and map the evidence on the efficacy and safety of intravenous lipid emulsion for treating LAST during pregnancy...
February 14, 2024: BMC Pregnancy and Childbirth
https://read.qxmd.com/read/38332962/effectiveness-of-alprostadil-for-ductal-patency
#15
JOURNAL ARTICLE
Caitlin M Gordon, Jason T Tan, Roxane R Carr
OBJECTIVES: This study aims to describe the effectiveness of low initial alprostadil dosages to maintain a patent ductus arteriosus (PDA) in infants with ductal-dependent congenital heart disease (DDCHD). Secondary objectives were to describe any adverse drug events, describe prescribing trends, describe ductus arteriosus diameter changes, and compare the safety and efficacy of very low and low initial alprostadil dosage regimens. METHODS: This retrospective observational cohort study at the British Columbia's Women's and Children's Hospital neonatal intensive care unit and pediatric intensive care unit examined neonates admitted with DDCHD who received alprostadil to maintain ductal patency...
2024: Journal of Pediatric Pharmacology and Therapeutics: JPPT: the Official Journal of PPAG
https://read.qxmd.com/read/38324898/hemodynamic-effects-of-noradrenaline-in-neonatal-septic-shock-a-prospective-cohort-study
#16
JOURNAL ARTICLE
Aditya Kallimath, Reema Garegrat, Suprabha Patnaik, Yogen Singh, Naharmal B Soni, Pradeep Suryawanshi
BACKGROUND: The incidence of neonatal septic shock in low-income countries is 26.8% with a mortality rate of 35.4%. The evidence of the hemodynamic effects of noradrenaline in neonates remains sparse. This study was carried out to evaluate the effects of noradrenaline in neonates with septic shock. METHODS: This was a single-center prospective cohort study in a tertiary care hospital's level III neonatal intensive care unit. Neonates with septic shock and those who received noradrenaline as a first-line vasoactive agent were included...
February 7, 2024: Journal of Tropical Pediatrics
https://read.qxmd.com/read/38320979/clinical-characteristics-outcomes-and-risk-factors-for-mortality-in-pregnant-puerperal-women-with-covid-19-admitted-to-icu-in-turkey-a-multicenter-retrospective-study-from-a-middle-income-country
#17
JOURNAL ARTICLE
Nur Baykara
BACKGROUND: Coronaviruses have been the cause of 3 major outbreaks during the last 2 decades. Information on coronavirus diseases in pregnant women is limited, and even less is known about seriously ill pregnant women. Data are also lacking regarding the real burden of coronavirus disease 2019 (COVID-19) infection in pregnant women from low/middle-income countries. The aim of this study was to determine the characteristics and clinical course of COVID-19 in pregnant/puerperal women admitted to ICUs in Turkey...
February 6, 2024: Journal of Intensive Care Medicine
https://read.qxmd.com/read/38306954/challenges-in-clinical-identification-of-right-ventricular-dysfunction-in-preterm-infants-with-persistent-pulmonary-hypertension-of-the-newborn
#18
JOURNAL ARTICLE
Faith Zhu, Caio Barbosa de Oliveira, Nada Mohsen, Ashraf Kharrat, Poorva Deshpande, Luc Mertens, Amish Jain
BACKGROUND: Right ventricular dysfunction, typically qualitatively diagnosed (Q-RVd) in preterm infants, requires echocardiography which is not always acutely available. We aimed to identify clinical indices of Q-RVd in very preterm infants (gestational age, GA <32 weeks) with persistent pulmonary hypertension of newborn (PPHN) and examine the reliability and validity of Q-RVd. METHODS: Forty-seven infants with mean ± SD GA of 26.8 ± 2...
January 23, 2024: Early Human Development
https://read.qxmd.com/read/38290539/false-laboratory-thyroid-function-tests-after-biotin-treatment-in-a-neonate-with-shock-and-suspect-of-metabolic-disorder
#19
JOURNAL ARTICLE
Martin Mavany, Oliver Blankenstein, Christoph Bührer, Christof Dame
No abstract text is available yet for this article.
January 30, 2024: Klinische Pädiatrie
https://read.qxmd.com/read/38276999/echocardiographic-characteristics-in-neonates-with-septic-shock
#20
JOURNAL ARTICLE
Kumari Gunjan, Manoj Modi, Anup Thakur, Arun Soni, Satish Saluja
Clinical parameters used for hemodynamic assessment and titration of vasopressor therapy in neonates with septic shock have several limitations. Functional echocardiography is an emerging tool for bedside assessment of cardiac function and may be useful for diagnosis of shock and assessing the response to therapy. Data regarding echocardiographic parameters in neonates with shock is lacking. This prospective observational study was conducted in a Level III NICU with the primary objective of comparing echocardiographic characteristics of neonates with septic shock at diagnosis, following fluid boluses, and after maximum inotropic support [A1]...
January 26, 2024: European Journal of Pediatrics
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