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https://www.readbyqxmd.com/read/29038147/imputation-of-baseline-ldl-cholesterol-concentration-in-patients-with-familial-hypercholesterolemia-on-statins-or-ezetimibe
#1
Isabelle Ruel, Sumayah Aljenedil, Iman Sadri, Émilie de Varennes, Robert A Hegele, Patrick Couture, Jean Bergeron, Eric Wanneh, Alexis Baass, Robert Dufour, Daniel Gaudet, Diane Brisson, Liam R Brunham, Gordon A Francis, Lubomira Cermakova, James M Brophy, Arnold Ryomoto, G B John Mancini, Jacques Genest
BACKGROUND: Familial hypercholesterolemia (FH) is the most frequent genetic disorder seen clinically and is characterized by increased LDL cholesterol (LDL-C) (>95th percentile), family history of increased LDL-C, premature atherosclerotic cardiovascular disease (ASCVD) in the patient or in first-degree relatives, presence of tendinous xanthomas or premature corneal arcus, or presence of a pathogenic mutation in the LDLR, PCSK9, or APOB genes. A diagnosis of FH has important clinical implications with respect to lifelong risk of ASCVD and requirement for intensive pharmacological therapy...
October 16, 2017: Clinical Chemistry
https://www.readbyqxmd.com/read/29021905/the-waterpolo-shoulder-paradigm-results-of-ultrasound-surveillance-at-poolside
#2
Felice Galluccio, Eleonora Bellucci, Francesco Porta, Lorenzo Tofani, Amato De Paulis, Diana Bianchedi, Tatiana Barskova, Marco Matucci-Cerinic
BACKGROUND: Waterpolo consists of a combination of swimming and throwing with close contact between players. The shoulder is the most frequently injured joint, with a combination of rotator cuff tear and tendinopathy, long head biceps tendinopathy, superior labral lesions and shoulder impingement. This unique combination is a challenge for the clinician who must determine which of these shoulder pathologies is responsible for the onset of pain and the best strategy to rehabilitate the joint and prevent recurrence...
2017: BMJ Open Sport & Exercise Medicine
https://www.readbyqxmd.com/read/28969821/editorial-commentary-increased-risk-of-second-ruptures-and-poorer-outcomes-after-anterior-cruciate-ligament-injury-and-reconstruction-in-hypermobile-athletes-a-potential-synergism-of-passive-ligamentous-and-active-muscular-control-of-dynamic-knee-stability
#3
EDITORIAL
Timothy E Hewett
Graft failure rates were higher and inferior subjective outcomes were observed after anterior cruciate ligament reconstruction in patients with generalized hypermobility. This is a clear and corroborative finding that is highly consilient with other reports of similar studies from the published literature. However, controversy remains regarding other potentially predictive and confounding variables. For example, age, activity level, sex, and dynamic neuromuscular control were not considered in this interesting, important, and potentially impactful study...
October 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/28951280/the-relationship-of-the-anterior-articular-capsule-to-the-adjacent-subscapularis-an-anatomic-and-histological-study
#4
Chi-Ju Lee, Ming-Long Yeh, Chih-Hsun Chang, Florence L Chiang, Chih-Kai Hong, Wei-Ren Su
INTRODUCTION: The purpose of this study was to delineate the anatomic relationship between the anterior articular capsule and the adjacent subscapularis by measuring the dimensions of the anterior articular capsule attachment and the subscapularisfootprint on the humerus, as well as investigating the interface between the two structures. MATERIALS AND METHODS: Three shoulder specimensunderwent histological analysis; forhistological analysis, cross-sections through the subscapularis-capsulecomplex were harvested at the tendinous and muscular insertion sites...
September 22, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28948372/comparative-anatomy-on-3-d-mri-of-the-urogenital-sinus-and-the-periurethral-area-before-and-during-the-second-stage-of-labor-during-childbirth
#5
Jean-Christophe Maran, Lucie Cassagnes, Vincent Delmas, Dominique Musset, René Frydman, Gérard Mage, Michel Canis, Louis Boyer, Olivier Ami
PURPOSE OF THE STUDY: To describe the observable MRI changes in the urogenital sinus during the second stage of labor and delivery by comparing the changes in the positions of the anatomical structures of the maternal perineum using MRI-based vector 3-D models. MATERIALS AND METHODS: Seven pregnant women underwent 3-D MRI sequences using a Philips 1 T Panorama open MRI during the pre-labor period and during the second stage of labor. A 3-D vector reconstruction platform (BABYPROGRESS, France) enabled the transformation of volumes of 2-D images into finite element meshes...
September 26, 2017: Surgical and Radiologic Anatomy: SRA
https://www.readbyqxmd.com/read/28936378/a-novel-type-of-coracobrachialis-muscle-variation-and-a-proposed-new-classification
#6
Georgi P Georgiev, Boycho Landzhov, R Shane Tubbs
During a routine anatomical dissection in the right brachium of a 75-year-old male cadaver, a novel variation of the coracobrachialis muscle (CB) was discovered. It consisted of three parts: proximal, starting from the upper border of the scapula; medial, presenting the well-accessed CB; and distal, formed by a proximal tendinous part that arose from the coracoid process and then transitioned into a well-defined muscle body and a distal tendinous part attached to the medial epicondyle. We also present a new systematic classification of CB variations, dividing them into two simple groups...
July 13, 2017: Curēus
https://www.readbyqxmd.com/read/28932697/thoracic-wall-trauma-misdiagnosed-lesions-on-radiographs-and-usefulness-of-ultrasound-multidetector-computed-tomography-and-magnetic-resonance-imaging
#7
REVIEW
Xavier Tomas, Catherine Facenda, Nuno Vaz, Edgar Augusto Castañeda, Montserrat Del Amo, Ana Isabel Garcia-Diez, Jaime Pomes
Blunt injuries to the chest wall are an important chapter on emergency room (ER) departments, being the third most common injuries in trauma patients which ominous complications could appear. This article describes different types of traumatic events affecting the chest wall, which maybe misdiagnosed with conventional X-ray. Special emphasis has been done in computed tomography (CT) and multidetector CT (MDCT) imaging. This technique is considered the "gold-standard" for those traumatic patients, due to its fast acquisition covering the whole area of interest in axial plane, reconstructing multiplanar (2D, 3D) volume-rendered images with a superb quality and angiographic CT capabilities for evaluating vascular damage...
August 2017: Quantitative Imaging in Medicine and Surgery
https://www.readbyqxmd.com/read/28926470/acceptability-and-practicality-of-the-turkish-translation-of-pediatric-gait-arm-legs-and-spine-in-turkish-children
#8
Ezgi Deniz Batu, Özge Keniş Coşkun, Hafize Emine Sönmez, Duygu Karali, Elif Arslanoğlu Aydin, Yelda Bilginer, Evrim Karadağ Saygi, Seza Özen
BACKGROUND: The pediatric Gait, Arms, Leg, and Spine (pGALS) is a practical questionnaire for musculoskeletal (MSK) system evaluation in school-age children. OBJECTIVE: The aim of this study was to evaluate the acceptability/practicality of pGALS Turkish translation in Turkey (cross-sectional study). METHODS: The Turkish translation of pGALS was administered to children (4-18 years) who attended to the Pediatric Emergency Department of Hacettepe University, Ankara, Turkey, and the outpatient clinic of the Physical Therapy and Rehabilitation Department of Marmara University, Istanbul, Turkey, during 1 month in 2016...
September 19, 2017: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/28925568/the-fibular-meniscus-of-the-kangaroo-as-an-adaptation-against-external-tibial-rotation-during-saltatorial-locomotion
#9
Adrian C Miller, Martin A Cake, Natalie M Warburton
The kangaroo knee is, as in other species, a complex diarthrodial joint dependent on interacting osseous, cartilaginous and ligamentous components for its stability. While principal load bearing occurs through the femorotibial articulation, additional lateral articulations involving the fibula and lateral fabella also contribute to the functional arrangement. Several fibrocartilage and ligamentous structures in this joint remain unexplained or have been misunderstood in previous studies. In this study, we review the existing literature on the structure of the kangaroo 'knee' before providing a new description of the gross anatomical and histological structures...
September 19, 2017: Journal of Anatomy
https://www.readbyqxmd.com/read/28918489/yersinia-enterocolitica-biotype-1a-a-possible-new-trigger-of-reactive-arthritis
#10
Riitta Tuompo, Timo Hannu, Elisa Huovinen, Leila Sihvonen, Anja Siitonen, Marjatta Leirisalo-Repo
Yersinia enterocolitica (YE) biotype 1A is generally considered non-pathogenic, and the role of it in causing reactive musculoskeletal complications is unclear. We evaluated the capability of YE biotype 1A to induce reactive arthritis (ReA) and other reactive musculoskeletal symptoms. Analysis of self-reported musculoskeletal symptoms was supplemented with a telephone interview (with a permission to acquire copies of patient files from a local physician or hospital) and/or clinical examination of subjects with recent musculoskeletal symptoms after a positive stool culture for YE...
November 2017: Rheumatology International
https://www.readbyqxmd.com/read/28899560/nerve-injuries-to-the-volar-aspect-of-the-hand-a-comparison-of-the-reliability-of-the-weber-static-test-versus-the-gauze-test
#11
Charles Bijon, Juan José Hidalgo Diaz, Chiara Pizza, Sybille Facca, Alexis Pereira, Philippe Liverneaux
When examining lacerations to the volar aspect of the hand a gauze test may usually be performed to detect nerve injuries. However, published literature suggests that its sensitivity and specificity are lower than 100%. The aim of this study was to determine whether a Weber static (main hypothesis) and dynamic test or a Semmes-Weinstein test (secondary hypotheses) could be a more reliable test than the gauze test to rule out any nerve injury and avoid unnecessary wound explorations. Our case series included a total of 102 patients presenting with 123 palmar lacerations and 158 nerve injuries...
September 8, 2017: Injury
https://www.readbyqxmd.com/read/28898104/rotator-cuff-calcific-tendinitis-ultrasound-guided-needling-and-lavage-versus-subacromial-corticosteroids-five-year-outcomes-of-a-randomized-controlled-trial
#12
Pieter Bas de Witte, Arjen Kolk, Ferdinand Overes, Rob G H H Nelissen, Monique Reijnierse
BACKGROUND: Barbotage (needling and lavage) is often applied in the treatment of calcific tendinitis of the rotator cuff (RCCT). In a previously published randomized controlled trial, we reported superior clinical and radiological 1-year outcomes for barbotage combined with a corticosteroid injection in the subacromial bursa (SAIC) compared with an isolated SAIC. There are no trials with a midterm or long-term follow-up of barbotage available. PURPOSE: To compare the 5-year results of 2 regularly applied treatments of RCCT: ultrasound (US)-guided barbotage combined with a SAIC (group 1) versus an isolated US-guided SAIC (group 2)...
September 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28891546/work-related-musculoskeletal-pain-among-lebanese-dentists-an-epidemiological-study
#13
S Bou Jaoude, N Naaman, E Nehme, J Gebeily, M Daou
INTRODUCTION: The aim of this study was to evaluate the prevalence of musculoskeletal disorders and identify their associated factors among a group of Lebanese dentists. MATERIALS AND METHODS: A total of 314 Lebanese, dentists completed an anonymous questionnaire that focused on occupational health problems. This study was approved by the ethics committee of Saint-Joseph University of Beirut, Lebanon. The statistical analyses were performed using SPSS for windows...
August 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/28889228/intraosseous-migration-of-tendinous-calcifications-two-case-reports
#14
A Marinetti, M Sessa, A Falzone, S W Della Sala
Calcific tendinopathy of the rotator cuff is a common cause of shoulder pain. Inflammation of the rotator cuff tendons may be complicated by adjacent bone erosion and subsequent migration of calcific deposits within the bone resulting in marrow inflammation. Bone marrow involvement is not readily visible using X-ray and ultrasound (US) and further testing is necessary. Magnetic resonance imaging (MRI) is a highly sensitive technique that can detect a focal bone T1 and T2-weighted hypointensity with bone marrow edema-like signal and cortical erosion...
September 9, 2017: Skeletal Radiology
https://www.readbyqxmd.com/read/28888715/acute-traumatic-rupture-of-the-patellar-tendon-in-pediatric-population-case-series-and-review-of-the-literature
#15
Mohamed Abdelhamid Ali Yousef, Scott Rosenfeld
BACKGROUND: Intact knee extensor mechanism is required for the normal function of the lower extremity. Patellar tendon rupture is a relatively rare injury with peak age incidence around 40 years and usually occurs midsubstance. The occurrence of pure patellar tendon rupture without bony avulsion is an extremely rare injury in the pediatric population with few cases reported in the literature with limited information regarding frequency, complications, and outcomes in children. However, due to increased participation in sports and high-energy recreational activities during childhood, the frequency of such injuries has progressively increased...
September 1, 2017: Injury
https://www.readbyqxmd.com/read/28857221/sonographic-overview-of-usual-and-unusual-disorders-of-the-rectus-femoris-tendon-origins
#16
Antoine Moraux, Vincent Balbi, Eric Cockenpot, Laurent Vandenbussche, Bruno Miletic, Romain Letartre, Chadi Khalil
Rectus femoris muscle proximal injuries are not rare conditions. The proximal rectus femoris tendinous anatomy is complex and may be affected by traumatic, microtraumatic, or nontraumatic disorders. A good knowledge of the proximal rectus femoris anatomy allows a better understanding of injury and disorder patterns. A new sonographic lateral approach was recently described to assess the indirect head of the proximal rectus femoris, hence allowing for a complete sonographic assessment of the proximal rectus femoris tendons...
August 31, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28837460/normal-palmar-anatomy-and-variations-that-impact-median-nerve-decompression
#17
John G Seiler, Jimmy H Daruwalla, Samuel H Payne, Gregory K Faucher
Annually, carpal tunnel release is one of the most commonly executed orthopaedic procedures. Despite the frequency of the procedure, complications may occur as a result of anatomic variations. Understanding both normal and variant anatomy, including anomalies in neural, vascular, tendinous, and muscular structures about the carpal tunnel, is fundamental to achieving both safe and efficacious surgery. Reviewing and aggregating this information reveals certain principles that may lead to the safest possible surgical approach...
September 2017: Journal of the American Academy of Orthopaedic Surgeons
https://www.readbyqxmd.com/read/28836021/hip-abductor-tendinitis-after-acl-reconstruction-with-patellar-tendon-graft-in-soccer-players-a-new-clinical-complication
#18
George Mouzopoulos, Christos Vlachos, Anastasia Tsembeli, Leonidas Karantzalis, Konstantinos Vlachos
 Although ACL reconstruction remains a complex procedure with possible complications, affecting mainly the knee function, but no complications affecting the hip function have been already mentioned in the literature. Here in, we discuss the demographics, clinical course and outcomes of a rare complication such as hip abductors tendinitis, developed in soccer amateur athletes after ACL reconstruction with patellar tendon graft.
August 23, 2017: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/28832199/acute-calcific-tendinitis-of-the-index-finger-in-a-child
#19
Frances M Walocko, Ian C Sando, Steven C Haase, Jeffrey H Kozlow
BACKGROUND: Calcific tendinitis is characterized by calcium hydroxyapatite crystal deposition within tendons and is a common cause of musculoskeletal pain in adults. Its clinical manifestations may be acute, chronic, or asymptomatic. Acute calcific tendinitis is self-resolving condition that is rarely reported in the pediatric population and may be overlooked for more common processes, leading to unnecessary treatment. METHODS: A chart reivew was performed of a single case of acute calcific tendonitis of the index finger in a child...
September 2017: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/28831234/ultrasound-guided-needling-vs-radial-shockwave-therapy-in-calcific-tendinitis-of-the-shoulder-a-prospective-randomized-trial
#20
Friso A De Boer, Femke Mocking, Eelco M Nelissen, Paulien M Van Kampen, Pol E Huijsmans
PURPOSE: Ultrasound Needling(UN) and Radial Shockwave(RSWT) aim to dissolve deposits in Shoulder Calcific tendinitis. METHODS: RCT in 25 patients to compare short term effectiveness. Outcome measures were pain and functional outcome at 6 weeks and 1 year and decrease of deposits after 6 weeks. RESULTS: UN decreased deposit more than RSWT(P = 0.029). After 6 weeks, Constant, NRS and Oxford improved more in UN. After 1 year, there was no significant difference in NRS(p = 0...
December 2017: Journal of Orthopaedics
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