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Neonatal tpn review

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https://www.readbyqxmd.com/read/27884125/epidemiology-of-and-risk-factors-for-neonatal-candidemia-at-a-tertiary-care-hospital-in-western-china
#1
Jichang Chen, Yongjiang Jiang, Ba Wei, Yanling Ding, Shaolin Xu, Peixu Qin, Jinjian Fu
BACKGROUND: The prevalence and clinical characteristics of neonatal candidemia are poorly understood in western China. The aim of our study was to evaluate the epidemiological features of neonatal candidemia in the Liuzhou Maternity and Child Healthcare Hospital. METHODS: A retrospective case-control study was conducted between January 2012 and November 2015. Electronic databases were reviewed and data on Candida species were isolated from blood cultures and candidemia incidence, risk factors, and mortality were extracted...
November 24, 2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27713674/impact-of-computerized-provider-order-entry-on-total-parenteral-nutrition-in-the-neonatal-intensive-care-unit
#2
Kyle A Franco, Keliana O'Mara
OBJECTIVES: To determine if computerized provider order entry (CPOE) implementation impacts the time it takes for preterm neonates to reach their parenteral macronutrient goals. METHODS: Retrospective review of neonates <1750 g receiving parenteral nutrition (PN) before and after the implementation of CPOE. Primary outcome was the attainment of parenteral macronutrient goals. Secondary outcomes included time to attainment, the frequency of electrolyte abnormalities, and the incidence of required adjustments made to PN orders by verification pharmacists...
July 2016: Journal of Pediatric Pharmacology and Therapeutics: JPPT: the Official Journal of PPAG
https://www.readbyqxmd.com/read/27324459/a-global-perspective-of-the-roles-of-the-pharmacist-in-the-nicu
#3
Natalia Krzyzaniak, Beata Bajorek
OBJECTIVES: To describe pharmacist practice and roles performed in the neonatal intensive care unit (NICU) worldwide and to map these findings along the medicines management pathway (MMP). METHOD: Quasi-systematic review. SEARCH STRATEGY: Google Scholar, Medline/PubMed and Embase were searched utilising the selected MeSH terms. RESULTS: Thirty sources of information were reviewed. Overall, pharmacist practice in the NICU involves a wide-range of roles, with the most commonly reported involving patient medication chart review, therapeutic drug monitoring and the provision of medication information...
June 21, 2016: International Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/26995515/liquid-chromatography-mass-spectroscopy-as-a-tool-in-the-rapid-diagnosis-of-biliary-atresia-a-pilot-study
#4
Marie Nguyen, Avafia Dossa, Jessica Zagory, Jamie Golden, Anne Roberts, Xiaowei Fu, Kasper Wang, Christopher P Gayer
INTRODUCTION: Biliary atresia (BA) is a neonatal obstructive cholangiopathy requiring rapid intervention to prevent end-stage liver failure and death. Low bile acid levels in stool, detectable with high-performance liquid chromatography-mass spectroscopy, may reflect extrahepatic biliary obstruction in cholestasis. HYPOTHESIS: Stool bile acid content can differentiate BA from non-BA forms of cholestasis. METHODS: Stool samples from four healthy and nine cholestatic patients were collected following internal review board approval...
June 2016: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/26965761/early-enteral-nutrition-in-neonates-with-partial-gastrectomy-a-multi-center-study
#5
MULTICENTER STUDY
Weiwei Jiang, Jie Zhang, Qiming Geng, Xiaoqun Xu, Xiaofeng Lv, Yongwei Chen, Xiang Liu, Weibing Tang
BACKGROUND AND OBJECTIVES: Compared with total parenteral nutrition (TPN), enteral nutrition is more suitable for patients post-operatively. Our aim was to determine the safety and feasibility of early enteral nutrition (EEN) using a jejunum feeding tube in neonates after undergoing a partial gastrectomy. METHODS AND STUDY DESIGN: This was a retrospective review of 46 patients who underwent partial gastrectomies for gastric perforation in our hospital. These patients were categorized into two groups (EEN group [n=24 patients], a jejunal feeding tube was inserted during surgery; and a control group [n=22 patients], a jejunal feeding tube was not placed)...
2016: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/26589959/etiologies-of-conjugated-hyperbilirubinemia-in-infancy-a-systematic-review-of-1692-subjects
#6
REVIEW
Lena E Gottesman, Michael T Del Vecchio, Stephen C Aronoff
BACKGROUND: The etiologies of conjugated hyperbilirubinemia in infancy are diverse. OBJECTIVE: Determine the prevalence rates of the specific etiologies of conjugated hyperbilirubinemia in infancy. DATA SOURCES: EMBASE and Pubmed were searched electronically and the bibliographies of selected studies were search manually. The search was conducted independently by two authors. STUDY SELECTION: (1) prospective or retrospective case series or cohort study with 10 or more subjects; (2) consecutive infants who presented with conjugated hyperbilirubinemia; (3) subjects underwent appropriate diagnostic work-up for conjugated hyperbilirubinemia; (4) no specific diagnoses were excluded in the studied cohort...
2015: BMC Pediatrics
https://www.readbyqxmd.com/read/26337780/severe-extravasation-injuries-in-neonates-a-report-of-34-cases
#7
Nikolaos Kostogloudis, Efterpi Demiri, Antonios Tsimponis, Dimitrios Dionyssiou, Sotirios Ioannidis, Ilias Chatziioannidis, Nikolaos Nikolaidis
INTRODUCTION: Extravasation injuries are a common and challenging problem in hospitalized newborns. Accidental infusion leakage into the surrounding tissues in immature infants may frequently result in skin necrosis, with significant risk of functional and cosmetic impairment. MATERIAL AND METHODS: In the present study we reviewed 34 cases of severe extravasation injuries occurring in 1,409 neonates hospitalized in a single neonatal unit over 24 months (incidence 2...
November 2015: Pediatric Dermatology
https://www.readbyqxmd.com/read/26217981/acute-kidney-injury-and-pneumothorax-are-risk-factors-for-mortality-in-persistent-pulmonary-hypertension-of-the-newborn-in-thai-neonates
#8
Narongsak Nakwan, Surassawadee Pithaklimnuwong
OBJECTIVES: To describe the clinical characteristics, diagnostic methods, treatment modalities, and complications, and identify the mortality risk factors, of infants with short-term persistent pulmonary hypertension of the newborn (PPHN). METHODS: The clinical data of infants diagnosed with PPHN at Hat Yai Hospital from January 2010 to February 2014 were retrospectively reviewed. Cox proportional hazard regression analysis was performed to assess factors associated with mortality...
2016: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/26214750/treatment-of-neonatal-fungal-infective-endocarditis-with-recombinant-tissue-plasminogen-activator-in-a-low-birth-weight-infant-case-report-and-review-of-the-literature
#9
REVIEW
Aslan Babayigit, Burcu Cebeci, Gokhan Buyukkale, Seda Yılmaz Semerci, Helen Bornaun, Kazim Oztarhan, Muge Gokce, Merih Cetinkaya
With advances in medical sciences, an increase in survival rates of low birth weight; increased incidence in use of catheter and antibiotics, and total parenteral nutrition are reported, therefore, the rate of fungal infections in late and very late onset neonatal sepsis have increased. Although fungal endocarditis rarely occur in newborns, it has a high morbidity and mortality. Antifungal therapy is often insufficient in cases who develop fungal endocarditis and surgical treatment is not preferred due to its difficulty and high mortality...
October 2015: Mycoses
https://www.readbyqxmd.com/read/26122809/prenatal-risk-factors-and-outcomes-in-gastroschisis-a-meta-analysis
#10
REVIEW
Francesco D'Antonio, Calogero Virgone, Giuseppe Rizzo, Asma Khalil, David Baud, Titia E Cohen-Overbeek, Marina Kuleva, Laurent J Salomon, Maria Elena Flacco, Lamberto Manzoli, Stefano Giuliani
BACKGROUND AND OBJECTIVE: Gastroschisis is a congenital anomaly with increasing incidence, easy prenatal diagnosis and extremely variable postnatal outcomes. Our objective was to systematically review the evidence regarding the association between prenatal ultrasound signs (intraabdominal bowel dilatation [IABD], extraabdominal bowel dilatation, gastric dilatation [GD], bowel wall thickness, polyhydramnios, and small for gestational age) and perinatal outcomes in gastroschisis (bowel atresia, intra uterine death, neonatal death, time to full enteral feeding, length of total parenteral nutrition and length of in hospital stay)...
July 2015: Pediatrics
https://www.readbyqxmd.com/read/25969129/pleurodesis-with-povidone-iodine-for-refractory-chylothorax-in-newborns-personal-experience-and-literature-review
#11
REVIEW
Federico Scottoni, Fabio Fusaro, Andrea Conforti, Francesco Morini, Pietro Bagolan
INTRODUCTION: Refractory chylothorax is a severe clinical issue, particularly in neonates. Conventional primary approach is based on diet with medium-chain fatty acids and/or total parenteral nutrition. In nonresponders, proposed second line treatments include chemical or surgical pleurodesis, thoracic duct ligation, pleuroperitoneal shunting and pleurectomy but none of these have been shown to be superior to other in terms of resolution rate and safety. Our aim is to report our experience on povidone-iodine use for chemical pleurodesis in newborn infants with chylothorax unresponsive to conservative treatment...
October 2015: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/25934326/the-prevention-diagnosis-and-management-of-central-venous-line-infections-in-children
#12
REVIEW
Emily Chesshyre, Zoy Goff, Asha Bowen, Jonathan Carapetis
With advancing paediatric healthcare, the use of central venous lines has become a fundamental part of management of neonates and children. Uses include haemodynamic monitoring and the delivery of lifesaving treatments such as intravenous fluids, blood products, antibiotics, chemotherapy, haemodialysis and total parenteral nutrition (TPN). Despite preventative measures, central venous catheter-related infections are common, with rates of 0.5-2.8/1000 catheter days in children and 0.6-2.5/1000 catheter days in neonates...
June 2015: Journal of Infection
https://www.readbyqxmd.com/read/25755236/prediction-models-for-neonatal-health-care-associated-sepsis-a-meta-analysis
#13
REVIEW
Evelien Hilde Verstraete, Koen Blot, Ludo Mahieu, Dirk Vogelaers, Stijn Blot
BACKGROUND AND OBJECTIVES: Blood culture is the gold standard to diagnose bloodstream infection but is usually time-consuming. Prediction models aim to facilitate early preliminary diagnosis and treatment. We systematically reviewed prediction models for health care-associated bloodstream infection (HABSI) in neonates, identified superior models, and pooled clinical predictors. DATA SOURCES: LibHub, PubMed, and Web of Science. METHODS: The studies included designed prediction models for laboratory-confirmed HABSI or sepsis...
April 2015: Pediatrics
https://www.readbyqxmd.com/read/25740740/early-enteral-nutrition-for-upper-digestive-tract-malformation-in-neonate
#14
Weiwei Jiang, Xiaofeng Lv, Xiaoqun Xu, Qiming Geng, Jie Zhang, Weibing Tang
BACKGROUND: Early enteral nutrition (EEN) is better than total parenteral nutrition (TPN) for many reasons. Our aim was to determine the safety and feasibility of EEN using a jejunum feeding tube in the duodenum or jejunum for congenital obstruction in neonates post-operatively. METHODS: This was a retrospective review of 120 patients who had duodenal and jejunal congenital obstructions in our hospital. The patients were categorized into two groups (EEN group [n=70 patients] and control group [n=50 patients])...
2015: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/25492029/natural-history-of-conjugated-bilirubin-trajectory-in-neonates-following-parenteral-nutrition-cessation
#15
Nisha Mangalat, Cynthia Bell, April Graves, Essam M Imseis
BACKGROUND: There is little published data regarding the rate of bilirubin clearance in newborns following total parenteral nutrition (TPN) cessation, particularly in the neonatal intensive care unit (NICU) population without intestinal failure. METHODS: The primary aim of this retrospective chart review was to determine the duration and severity of bilirubin elevation in neonates without intestinal failure. Secondary aims were to determine factors that would influence the duration and severity of this biochemical elevation...
2014: BMC Pediatrics
https://www.readbyqxmd.com/read/25346899/surgical-ligation-on-significant-patent-ductus-arteriosus-in-very-low-birth-weight-infants-comparison-between-early-and-late-ligations
#16
Jun Ho Lee, Sun Kyun Ro, Hyun Ju Lee, Hyun Kyung Park, Won-Sang Chung, Young Hak Kim, Jeong Ho Kang, Hyuck Kim
BACKGROUND: We aimed to evaluate the efficacy and safety of early surgical ligation (within 15 days of age) over late surgical ligation (after 15 days of age) by a comparative analysis of very low birth weight (VLBW) infants undergoing surgical correction for symptomatic patent ductus arteriosus (PDA) over the course of 6 years in our hospital. METHODS: We retrospectively reviewed all the medical records in the neonatal intensive care unit at Hanyang University Seoul Hospital, from March 2007 to May 2013, to identify VLBW infants (< 1,500 g) who underwent surgical PDA ligation...
October 2014: Korean Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/25334511/chylothorax-due-to-trauma-from-bouncy-house
#17
Kelly Welker, Shimoni Dharia
Pleural Student/Resident Case Report PostersSESSION TYPE: Medical Student/Resident Case ReportPRESENTED ON: Tuesday, October 28, 2014 at 01:30 PM - 02:30 PMINTRODUCTION: Spontaneous chylothorax is a rare cause of pleural effusions outside of the neonatal period. A case of traumatic chylothorax and spinal contusion in a toddler is described without any overt signs of injury.CASE PRESENTATION: A healthy fifteen month female presented to the emergency room with inability to bear weight. Earlier that day, she played in a bounce house and upon returning home she could not ambulate...
October 1, 2014: Chest
https://www.readbyqxmd.com/read/25318631/current-trends-and-future-challenges-in-neonatal-parenteral-nutrition
#18
REVIEW
D H Adamkin, P G Radmacher
A number of adaptations in total parenteral nutrition (TPN) protocols and practices for preterm neonates have been realized in the past several years, resulting in better survival and developmental outcomes. The early provision of appropriate concentrations of amino acids and energy are now recommended in evidence-based guidelines. Standardized TPN formulations are now available for many patients and may be associated with cost savings and improved adherence to guidelines. Several advantages of these preparations, including promotion of safer administration, consistent adherence to guidelines, and overall best practices, have been well documented...
January 1, 2014: Journal of Neonatal-perinatal Medicine
https://www.readbyqxmd.com/read/25306190/minimizing-the-risk-of-preoperative-brain-injury-in-neonates-with-aortic-arch-obstruction
#19
MULTICENTER STUDY
Selma O Algra, Felix Haas, Kenneth J Poskitt, Floris Groenendaal, Antonius N J Schouten, Nicolaas J G Jansen, Anthony Azakie, Sanjiv Gandhi, Andrew Campbell, Steven P Miller, Patrick S McQuillen, Linda S de Vries
OBJECTIVE: To determine whether prenatal diagnosis lowers the risk of preoperative brain injury by assessing differences in the incidence of preoperative brain injury across centers. STUDY DESIGN: From 2 prospective cohorts of newborns with complex congenital heart disease studied by preoperative cerebral magnetic resonance imaging, one cohort from the University Medical Center Utrecht (UMCU) and a combined cohort from the University of California San Francisco (UCSF) and University of British Columbia (UBC), patients with aortic arch obstruction were selected and their imaging and clinical course reviewed...
December 2014: Journal of Pediatrics
https://www.readbyqxmd.com/read/25253364/total-parenteral-nutrition-associated-cholestasis-and-risk-factors-in-preterm-infants
#20
Turki M Alkharfy, Rubana Ba-Abbad, Anjum Hadi, Badr H Sobaih, Khalid M AlFaleh
BACKGROUND/AIM: Development of hepatic dysfunction is a well-recognized complication of total parenteral nutrition in preterm infants. Previous studies reported the incidence of total parenteral nutrition-associated cholestasis and described possible contributing factors to its pathogenesis, but little is done trying to determine its possible predictive risk factors. The aims of this study was to determine the incidence of total parenteral nutrition-associated cholestasis and to develop a possible predictive model for its occurrence...
September 2014: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
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