Chensheng Pan, Guo Li, Wenzhe Sun, Jinfeng Miao, Yanyan Wang, Yan Lan, Xiuli Qiu, Xin Zhao, He Wang, Zhou Zhu, Suiqiang Zhu
BACKGROUND: Post-stroke depression (PSD) can be conceptualized as a complex network where PSD symptoms (PSDS) interact with each other. The neural mechanism of PSD and interactions among PSDS remain to be elucidated. This study aimed to investigate the neuroanatomical substrates of, as well as the interactions between, individual PSDS to better understand the pathogenesis of early-onset PSD. METHODS: A total of 861 first-ever stroke patients admitted within 7 days poststroke were consecutively recruited from three independent hospitals in China...
February 21, 2023: BMC Psychiatry