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https://www.readbyqxmd.com/read/29782059/testicular-histomorphometry-and-the-proliferative-and-apoptotic-activities-of-the-seminiferous-epithelium-in-syrian-hamster-during-spontaneous-recrudescence-after-exposure-to-short-photoperiod
#1
Jesús Martínez-Hernández, Vicente Seco-Rovira, Ester Beltrán-Frutos, Concepción Ferrer, Manuel Canteras, María Del Mar Sánchez-Huertas, Luis Miguel Pastor
Syrian hamsters are photoperiodic rodents in which reproduction, including testicular function, is stimulated by long photoperiod exposure and curtailed by exposure to a short photoperiod. The objectives of this study were to characterize the testis histomorphometrically and to determine the role of the proliferation and apoptosis phenomena in the recovery of the seminiferous epithelium during spontaneous recrudescence after exposure to short photoperiod. The study was performed using conventional light microscopy, proliferating cell nuclear antigen and terminal deoxynucleotidyl transferase (TdT)-mediated dUTP in situ nick end labelling staining, image analysis software, and transmission electron microscopy in three recrudescence groups: initial recrudescence (IR), advanced recrudescence (AR) and total recrudescence (TR)...
May 21, 2018: Reproduction in Domestic Animals, Zuchthygiene
https://www.readbyqxmd.com/read/29781861/clinico-pathological-study-of-4-cases-of-pseudoherpetic-grover-disease-the-same-as-vesicular-grover-disease
#2
Tania M Capusan, María Herrero-Moyano, Javier Fraga, Mar Llamas-Velasco
INTRODUCTION: Grover disease (GD) was described with 4 histopathological patterns, but later wide histopathological studies found additional ones including vesicular GD. From 2014, 2 new patterns, GD with epidermolytic hyperkeratosis and pseudoherpetic GD, have been proposed. OBJECTIVES: The authors present 4 cases of pseudoherpetic GD and review the 6 previously published cases to better characterize this variant clinically and histopathologically. RESULTS: Half of the patients were men...
June 2018: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/29781244/oprm1-influence-on-and-effectiveness-of-an-individualized-treatment-plan-for-prescription-opioid-use-disorder-patients
#3
Javier Muriel, César Margarit, Beatriz Planelles, María J Serralta, Carmen Puga, María-Del-Mar Inda, Esperanza Cutillas, Domingo Morales, José F Horga, Ana M Peiró
Screening for opioid use disorder should be considered in chronic non-cancer pain (CNCP) patients with long-term use of opioids. The aim of our study was to assess the effectiveness of an individualized treatment plan (ITP) for prescription opioid dependence that included screening of pharmacogenetic markers. An observational prospective study was performed using prescription opioid-dependent CNCP outpatients (n = 88). Patients were divided into nonresponders, responders, or high responders according to their response to the ITP...
May 20, 2018: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/29781061/performance-of-bi-2-o-3-tio-2-prepared-by-sol-gel-on-p-cresol-degradation-under-solar-and-visible-light
#4
Héctor H Vigil-Castillo, Aracely Hernández-Ramírez, Jorge L Guzmán-Mar, Norma A Ramos-Delgado, Minerva Villanueva-Rodríguez
Photocatalytic degradation of p-Cresol was evaluated using the mixed oxide Bi2 O3 /TiO2 (containing 2 and 20% wt. Bi2 O3 referred as TB2 and TB20) and was compared with bare TiO2 under simulated solar radiation. Materials were prepared by the classic sol-gel method. All solids exhibited the anatase phase by X-ray diffraction (XRD) and Raman spectroscopy. The synthesized materials presented lower crystallite size and Eg value, and also higher surface area as Bi2 O3 amount was increased. Bi content was quantified showing near to 70% of theoretical values in TB2 and TB20...
May 21, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29780678/meteoric-metal-chemistry-in-the-martian-atmosphere
#5
J M C Plane, J D Carrillo-Sanchez, T P Mangan, M M J Crismani, N M Schneider, A Määttänen
Recent measurements by the Imaging Ultraviolet Spectrograph (IUVS) instrument on NASA's Mars Atmosphere and Volatile EvolutioN mission show that a persistent layer of Mg+ ions occurs around 90 km in the Martian atmosphere but that neutral Mg atoms are not detectable. These observations can be satisfactorily modeled with a global meteoric ablation rate of 0.06 t sol-1 , out of a cosmic dust input of 2.7 ± 1.6 t sol-1 . The absence of detectable Mg at 90 km requires that at least 50% of the ablating Mg atoms ionize through hyperthermal collisions with CO2 molecules...
March 2018: Journal of Geophysical Research. Planets
https://www.readbyqxmd.com/read/29780296/metal-artifact-reduction-for-orthopedic-implants-brain-ct-angiography-in-patients-with-intracranial-metallic-implants
#6
Leonard Sunwoo, Sun-Won Park, Jung Hyo Rhim, Yeonah Kang, Young Seob Chung, Young-Je Son, Soo Chin Kim
Background: The purpose of this study was to qualitatively and quantitatively evaluate the effects of a metal artifact reduction for orthopedic implants (O-MAR) for brain computed tomographic angiography (CTA) in patients with aneurysm clips and coils. Methods: The study included 36 consecutive patients with 47 intracranial metallic implants (42 aneurysm clips, 5 coils) who underwent brain CTA. The computed tomographic images with and without the O-MAR were independently reviewed both quantitatively and qualitatively by two reviewers...
May 21, 2018: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/29779322/-impact-of-mycophenolate-mofetil-prophylaxis-duration-on-acute-graft-versus-host-disease-after-haploidentical-stem-cell-transplantation
#7
Y Q Sun, X J Huang, L P Xu, X H Zhang, C H Yan, K Y Liu, Y Wang
Objective: To investigate the impact of mycophenolate mofetil (MMF) prophylaxis duration on acute graft-versus-host disease (aGVHD) after haploidentical stem cell transplantation (haplo-HSCT) using 'Beijing Protocol'. Methods: Adult patients (≥14 years) received haplo-HSCT in Peking University Institute of Hematology from Sep, 2016 to Mar, 2017 were retrospectively reviewed if they fulfilled the criterias: ①diagnosed with hematological maligancies; ②standard-risk status at haplo-HSCT. A total of 237 patients [including 102 patients with long MMF duration (defined as started on day -9 with 100 mg/d, adjusted to 500 mg/d from day +30 and discontinued on day +45 to +60 or occurrence of CMV/EBV reactivation or late-onset hemorrhagic cytitis), and 135 patients with short MMF duration (defined as started on day -9 with 500 mg/d and discontinued on the day achieved neutrophil engraftment)] were reviewed...
April 14, 2018: Zhonghua Xue Ye Xue za Zhi, Zhonghua Xueyexue Zazhi
https://www.readbyqxmd.com/read/29777336/first-morphological-and-molecular-analysis-of-eucoleus-boehmi-like-eggs-in-dogs-from-argentina
#8
Carla Mariela Lavallén, Romina Sandra Petrigh, Martín Horacio Fugassa, Guillermo María Denegri, Marcela Cecilia Dopchiz
The canid parasites Eucoleus aerophilus (syn. Capillaria aerophila) and Eucoleus boehmi (syn. Capillaria boehmi) parasitize the lower and the upper respiratory tract, respectively. Reports and descriptions of these nematodes are scarce in Argentina, possibly due to misdiagnosis of morphologically similar trichuroids eggs, and the lack of knowledge about the species of Eucoleus in this geographical area. Scanning electron microscopy is a useful tool for identification of E. boehmi eggs based on the characteristics of the shell structure which differentiate between species...
May 18, 2018: Parasitology Research
https://www.readbyqxmd.com/read/29776852/indications-for-mars-mri-in-patients-treated-with-articular-surface-replacement-xl-total-hip-arthroplasty
#9
James W Connelly, Vincent P Galea, Inari Laaksonen, Sean J Matuszak, Rami Madanat, Orhun Muratoglu, Henrik Malchau
BACKGROUND: The purpose of this study was to identify which patient and clinical factors are predictive of adverse local tissue reaction (ALTR) and to use these factors to create a highly sensitive algorithm for indicating metal artifact reduction sequence magnetic resonance imaging (MARS-MRI) in Articular Surface Replacement (ASR) XL total hip arthroplasty patients. Our secondary aim was to compare our algorithm to existing national guidelines on when to take MARS-MRI in metal-on-metal total hip arthroplasty patients...
April 19, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29776384/competence-of-mosquitoes-native-to-the-united-kingdom-to-support-replication-and-transmission-of-rift-valley-fever-virus
#10
Sarah Lumley, Luis M Hernández-Triana, Daniel L Horton, Maria Del Mar Fernández de Marco, Jolyon M Medlock, Roger Hewson, Anthony R Fooks, Nicholas Johnson
BACKGROUND: Rift Valley fever phlebovirus (RVFV) is a mosquito-borne arbovirus causing severe disease in humans and livestock. It is endemic in Africa and spread to the Arabian Peninsula in 2000 raising concerns it could emerge in Europe. The ability of temperate mosquitoes from the United Kingdom (UK) to support replication and transmission of RVFV is unknown. METHODS: In this study, two colonised lines of Culex pipiens, wild-caught Aedes detritus and Ae. rusticus from the UK were infected with pathogenic strains of RVFV to assess their vector competence...
May 18, 2018: Parasites & Vectors
https://www.readbyqxmd.com/read/29775876/childhood-abuse-and-depression-in-adulthood-the-mediating-role-of-allostatic-load
#11
Sandra Scheuer, Nicole Wiggert, Tanja Maria Brückl, Yvonne Awaloff, Manfred Uhr, Susanne Lucae, Stefan Kloiber, Florian Holsboer, Marcus Ising, Frank H Wilhelm
BACKGROUND: Traumatic experiences during childhood are considered a major risk factor for depression in adulthood. Childhood trauma may induce physiological dysregulation with long-term effects of increased allostatic load until adulthood, which may lead to depression. Thus, our aim was to investigate whether allostatic load - which represents a multi-system measure of physiological dysregulation - mediates the association between childhood trauma and adult depression. METHODS: The study sample consisted of 324 depressed inpatients participating in the Munich Antidepressant Response Signature (MARS) project and 261 mentally healthy control participants...
April 22, 2018: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/29775242/mutations-in-mars-identified-in-a-specific-type-of-pulmonary-alveolar-proteinosis-alter-methionyl-trna-synthetase-activity
#12
Martine Comisso, Alice Hadchouel, Jacques de Blic, Marc Mirande
Biallelic missense mutations in MARS are responsible for rare but severe cases of pulmonary alveolar proteinosis (PAP) prevalent on the island of La Réunion. MARS encodes cytosolic methionyl-tRNA synthetase (MetRS), an essential translation factor. The multisystemic effects observed in patients with this form of PAP is consistent with a loss-of-function defect in an ubiquitously expressed enzyme. The pathophysiological mechanisms involved in MARS related PAP are currently unknown. In this work, we analyzed the effect of the PAP related mutations in MARS on the thermal stability and on the catalytic parameters of the MetRS mutants, relative to wild-type...
May 18, 2018: FEBS Journal
https://www.readbyqxmd.com/read/29775210/the-effect-of-simulated-space-radiation-on-the-n-glycosylation-of-human-immunoglobulin-g1
#13
Mate Szarka, Szabolcs Szilasi, Boglarka Donczo, Daniel Sarkozy, Istvan Rajta, Andras Guttman
On a roundtrip to Mars, astronauts are expectedly exposed to an approximate amount of radiation that exceeds the lifetime limits on Earth. This elevated radiation dose is mainly due to Galactic Cosmic Rays (GCR) and Solar Particle Events (SPE). Specific patterns of the N-glycosylation of human immunoglobulins have already been associated with various ailments such as autoimmune diseases, malignant transformation, chronic inflammation and ageing. The focus of our work was to investigate the effect of low-energy proton irradiation on the IgG N-glycosylation profile with the goal if disease associated changes could be detected during space travel and not altered by space radiation...
May 18, 2018: Electrophoresis
https://www.readbyqxmd.com/read/29775207/structural-and-technological-characterisation-of-pectin-extracted-with-sodium-citrate-and-nitric-acid-from-sunflower-heads
#14
Nerea Muñoz-Almagro, Fabián Rico-Rodriguez, Peter J Wilde, Antonia Montilla, Mar Villamiel
An optimisation of temperature, time and extracting agent concentration of pectin extraction from sunflower heads using sodium citrate and nitric acid (SP-SC and SP-NA) was carried out. At optimal conditions, the yield of extraction with nitric acid (SPO-NA) was 2-fold greater than the corresponding with sodium citrate (SPO-SC) (14.3 vs 7.7%, respectively). Regarding pectin structure, the galacturonic acid (GalA) content in both, SPO-SC and SPO-NA, was similar (∼85%). However, SPO-NA showed lower molecular weight (Mw) (88...
May 18, 2018: Electrophoresis
https://www.readbyqxmd.com/read/29773922/trilogy-a-planetary-geodesy-mission-concept-for-measuring-the-expansion-of-the-solar-system
#15
David E Smith, Maria T Zuber, Erwan Mazarico, Antonio Genova, Gregory A Neumann, Xiaoli Sun, Mark H Torrence, Dan-Dan Mao
The scale of the solar system is slowly changing, likely increasing as a result of solar mass loss, with additional change possible if there is a secular variation of the gravitational constant, G . The measurement of the change of scale could provide insight into the past and the future of the solar system, and in addition a better understanding of planetary motion and fundamental physics. Estimates for the expansion of the scale of the solar system are of order 1.5 cm year-1 AU-1 , which over several years is an observable quantity with present-day laser ranging systems...
April 2018: Planetary and Space Science
https://www.readbyqxmd.com/read/29773522/-a-child-with-chronic-cough-and-weight-loss
#16
María Moreno Ortega, María Del Mar Moreno García, Esther Pérez Borrego, Mirella Gaboli
No abstract text is available yet for this article.
May 14, 2018: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
https://www.readbyqxmd.com/read/29773003/antioxidant-action-of-an-aqueous-extract-of-royal-sun-medicinal-mushroom-agaricus-brasiliensis-agaricomycetes-in-rats-with-adjuvant-induced-arthritis
#17
Aline Cristine da Silva de Souza, Geferson de Almeida Gonсalves, Andréia Assunсão Soares, Anacharis B de Sá-Nakanishi, Ana Paula de Santi-Rampazzo, Maria Raquel Marсal Natali, Rosane Marina Peralta, Adelar Bracht
The purpose of this study was to evaluate possible effects of the administration of an aqueous Agaricus brasiliensis extract on the oxidative state of the liver, brain, and plasma in adjuvant-induced arthritic rats, a model for human rheumatoid arthritis. Daily doses of 400 mg · kg-1 were administered by gavage for 23 days. This treatment produced significant diminutions in protein carbonylation and lipid damage in the liver, brain, and plasma. It also diminished the tissue reactive oxygen species and increased the antioxidant capacity of the plasma...
2018: International Journal of Medicinal Mushrooms
https://www.readbyqxmd.com/read/29769727/microbial-signals-drive-pre-leukaemic-myeloproliferation-in-a-tet2-deficient-host
#18
Marlies Meisel, Reinhard Hinterleitner, Alain Pacis, Li Chen, Zachary M Earley, Toufic Mayassi, Joseph F Pierre, Jordan D Ernest, Heather J Galipeau, Nikolaus Thuille, Romain Bouziat, Manuel Buscarlet, Daina L Ringus, Yitang Wang, Ye Li, Vu Dinh, Sangman M Kim, Benjamin D McDonald, Matthew A Zurenski, Mark W Musch, Glaucia C Furtado, Sergio A Lira, Gottfried Baier, Eugene B Chang, A Murat Eren, Christopher R Weber, Lambert Busque, Lucy A Godley, Elena F Verdú, Luis B Barreiro, Bana Jabri
Somatic mutations in tet methylcytosine dioxygenase 2 (TET2), which encodes an epigenetic modifier enzyme, drive the development of haematopoietic malignancies1-7 . In both humans and mice, TET2 deficiency leads to increased self-renewal of haematopoietic stem cells with a net developmental bias towards the myeloid lineage1,4,8,9 . However, pre-leukaemic myeloproliferation (PMP) occurs in only a fraction of Tet2-/- mice8,9 and humans with TET2 mutations1,3,5-7 , suggesting that extrinsic non-cell-autonomous factors are required for disease onset...
May 16, 2018: Nature
https://www.readbyqxmd.com/read/29769132/toots-tastes-and-tester-shots-user-accounts-of-drug-sampling-methods-for-gauging-heroin-potency
#19
Sarah G Mars, Jeff Ondocsin, Daniel Ciccarone
BACKGROUND: Internationally, overdose is the primary cause of death among people injecting drugs. However, since 2001, heroin-related overdose deaths in the United States (US) have risen sixfold, paralleled by a rise in the death rate attributed to synthetic opioids, particularly the fentanyls. This paper considers the adaptations some US heroin injectors are making to protect themselves from these risks. METHODS: Between 2015 and 2016, a team of ethnographers collected data through semi-structured interviews and observation captured in field notes and video recording of heroin preparation/consumption...
May 16, 2018: Harm Reduction Journal
https://www.readbyqxmd.com/read/29768528/reliability-and-validity-of-the-medication-adherence-rating-scale-in-a-cohort-of-patients-with-schizophrenia-from-nigeria
#20
Godspower O Owie, Sunday O Olotu, Bawo O James
INTRODUCTION: Assessing adherence in schizophrenia facilitates interventions that optimize outcomes. Adherence rating questionnaires are feasible and non-intrusive; however, no validated measure exists in sub-Saharan Africa. We aimed to assess the psychometric properties of the 10-item Medication Adherence Rating Scale (MARS). METHODS: This was a cross-sectional study of a cohort of patients with schizophrenia (n=230). A sociodemographic questionnaire, the Mini International Neuropsychiatric Interview (MINI), Positive and Negative Syndrome Scale (PANSS), Scale for the Unawareness of Mental Disorder (SUMD) and the MARS were all administered by an interviewer...
May 14, 2018: Trends in Psychiatry and Psychotherapy
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