keyword
https://read.qxmd.com/read/34671872/sars-cov-2-infection-in-heart-transplant-recipients-a-systematic-literature-review-of-clinical-outcomes-and-immunosuppression-strategies
#21
REVIEW
Onyedika J Ilonze, Kareem Ballut, Roopa S Rao, Mark A Jones, Maya Guglin
The impact of SARS-CoV-2 infection on heart transplant recipients is unknown. Literature is limited to case reports and series. The purpose of this study is to identify the clinical features, outcomes, and immunosuppression strategies of heart transplant recipients with COVID-19 infection. A systematic review was conducted using the search term "Coronavirus" or COVID," "SARS-CoV-2," "cardiac transplantation," and "heart transplant." Case reports and retrospective studies were gathered by searching Medline/PubMed, Google Scholar, CINAHL, Cochrane CENTRAL, and Web of Science...
October 20, 2021: Heart Failure Reviews
https://read.qxmd.com/read/34603804/hantavirus-cardiopulmonary-syndrome-and-diffuse-alveolar-hemorrhage-in-the-era-of-covid-19
#22
Khizar Hamid, Swaminathan Perinkulam Sathyanarayanan, Touba Naim, Muhammad Hamza, Mirza Omer Mahmood Baig, Emad Abu Sitta
Hantavirus Cardiopulmonary Syndrome (HCPS) can occur after infection with Hantavirus which can occur by inhaling aerosolized rodent urine, feces, and saliva contaminated with the virus. It presents with the rapid development of pulmonary edema, respiratory failure, and cardiogenic shock with the hallmark being microvascular leakage. We report a patient with a history of alcohol abuse and recent exposure to mice and sick kittens who presented with cough with sputum production, shortness of breath, orthopnea, and new-onset lower extremity edema...
2021: Case Reports in Infectious Diseases
https://read.qxmd.com/read/34496964/toxic-epidermal-necrosis-associated-with-phenobarbitone-a-case-report-and-brief-review-of-the-literatures
#23
JOURNAL ARTICLE
Biniyam A Ayele, Kemal Ali, Eliyas Mulatu
BACKGROUND: Toxic epidermal necrolysis (TEN)/Stevens-Johnson syndrome (SJS) is the spectrum of severe, acute, mucocutaneous, T-cell mediated delayed type IV hypersensitivity reaction and universally related to different drugs. Phenobarbitone is known to cause hypersensitivity reactions with benign pattern; ranging from a mild to moderate rashes but not life-threatening reactions such as TEN/SJS. CASE REPORT: We report a 14-year-old asthmatic male patient admitted to a local hospital for an acute exacerbation of asthma, after he presented with shortness of breath, cough, and fever...
September 8, 2021: Allergy, Asthma, and Clinical Immunology
https://read.qxmd.com/read/34476315/culture-ordering-for-patients-with-new-onset-fever-a-survey-of-pediatric-intensive-care-unit-clinician-practices
#24
JOURNAL ARTICLE
Lauren D Booth, Anna C Sick-Samuels, Aaron M Milstone, James C Fackler, Lindsey K Gnazzo, David C Stockwell
INTRODUCTION: Accurate assessment of infection in critically ill patients is vital to their care. Both indiscretion and under-utilization of diagnostic microbiology testing can contribute to inappropriate antibiotic administration or delays in diagnosis. However, indiscretion in diagnostic microbiology cultures may also lead to unnecessary tests that, if false-positive, would incur additional costs and unhelpful evaluations. This quality improvement project objective was to assess pediatric intensive care unit (PICU) clinicians' attitudes and practices around the microbiology work-up for patients with new-onset fever...
September 2021: Pediatric Quality & Safety
https://read.qxmd.com/read/34446351/coronavirus-disease-covid-19-associated-delayed-onset-fulminant-myocarditis-in-patient-with-a-history-of-severe-acute-respiratory-syndrome-coronavirus-2-sars-cov-2-infection
#25
JOURNAL ARTICLE
Hiroyasu Ishikura, Junichi Maruyama, Kota Hoshino, Yuta Matsuoka, Masaya Yano, Tadaaki Arimura, Harutaka Katano, Seiya Kato, Taisuke Kitamura, Yoshihiko Nakamura
A healthy 35-year-old man was admitted to a rural hospital with coronavirus disease (COVID-19). During 14 days of hospitalization, he had no symptoms and was not given supplemental oxygen. About 3 weeks after discharge, he was re-admitted to the same hospital with new-onset continuous fever and general weakness. At the time of his second admission, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) RT-PCR was performed on a retro-nasal swab and the result was negative. Four days after admission, the patient was transferred to our intensive care unit (ICU) following deterioration of his respiratory and haemodynamic conditions, where he received mechanical ventilation, intra-aortic balloon pumping, and veno-arterial extracorporeal membrane oxygenation...
December 2021: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://read.qxmd.com/read/34368517/new-onset-type-1-diabetes-mellitus-with-diabetic-ketoacidosis-and-pancreatitis-in-a-patient-with-covid-19
#26
JOURNAL ARTICLE
Mostafa Alfishawy, Mahmoud Nassar, Mahmoud Mohamed, Moataz Fatthy, Riem M Elmessiery
Coronavirus Disease 2019 (COVID-19) had struck the world with health and economic catastrophes and recently with unusual autoimmune presentations, including new-onset Type 1 Diabetes. Herein we present a 17-year-old male patient who presented to the outptient clinic with fever, palpitation, and cough of four-week duration; he was referred to the emergency room and was found to have DKA. CT of the chest showed ground-glass opacities suggestive of COVID-19 pneumonia, and abdominal cuts showed dilated intrahepatic biliary radicles with pancreatic loculations suggestive of pancreatitis...
September 2021: Scientific African
https://read.qxmd.com/read/34191766/factors-associated-with-a-high-risk-return-visit-to-the-emergency-department-a-case-crossover-study
#27
JOURNAL ARTICLE
Chih-Wei Sung, Tsung-Chien Lu, Cheng-Chung Fang, Jia-You Lin, Huang-Fu Yeh, Chien-Hua Huang, Chu-Lin Tsai
BACKGROUND AND IMPORTANCE: Although factors related to a return emergency department (ED) visit have been reported, few studies have examined 'high-risk' return ED visits with serious adverse outcomes. Understanding factors associated with high-risk return ED visits may help with early recognition and prevention of these catastrophic events. OBJECTIVES: We aimed to (1) estimate the incidence of high-risk return ED visits, and (2) to investigate time-varying factors associated with these revisits...
October 1, 2021: European Journal of Emergency Medicine: Official Journal of the European Society for Emergency Medicine
https://read.qxmd.com/read/34045904/miller-fisher-variant-of-guillain-barr%C3%A3-syndrome-triggered-by-ventilator-associated-pneumonia
#28
Danah Aljaafari, Salam Almustafa, Abdulrahman Saleh Ali, Hosam Aldalbahi, Norah Ibrahim Albahli, Feras AlSulaiman, Anas Al Dehailan, Majed Alabdali
BACKGROUND: Miller Fisher syndrome (MFS), a triad of ophthalmoplegia, areflexia and ataxia, is one of the regional variants of Guillain-Barré syndrome (GBS) that might account for a quarter of all cases of GBS, especially in Asian countries. There is history of an antecedent upper respiratory tract infection in up to two thirds of MFS cases. However, association of MFS in adults and pneumonia is rarely reported and in those cases causative pathogen was Mycoplasma pneumonia e . To our knowledge, association of MFS and ventilator-associated pneumonia has never been reported...
2021: International Medical Case Reports Journal
https://read.qxmd.com/read/33722466/transmission-of-infection-among-health-care-personnel-performing-surgical-tracheostomies-on-covid-19-patients
#29
JOURNAL ARTICLE
Natarajan Angamuthu, Emelia Geraldine Gagasa, Daryll Baker, Janice Tsui, Rovan Evan D'Souza
BACKGROUND: Staff and patient safety are of paramount importance while performing a surgical tracheostomy (ST) during the corona virus disease (COVID-19) pandemic. The aim was to assess the incidence of COVID-19 infection among the healthcare personnel (HCP) performing ST on COVID-19 patients. METHODS: One hundred and twenty-two HCP participating in 71 ST procedures performed at our institution between 26th March 2020 and 27th May 2020 were identified. A COVID-19 health questionnaire was distributed among staff with their consent...
February 12, 2021: Surgeon: Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland
https://read.qxmd.com/read/33592371/the-association-between-covid-19-and-type-1-diabetes-mellitus-a-systematic-review
#30
JOURNAL ARTICLE
Mahmoud Nassar, Nso Nso, Bahaaeldin Baraka, Mostafa Alfishawy, Mahmoud Mohamed, Akwe Nyabera, Issac Sachmechi
BACKGROUND: /Aim: Various reports of the occurrence of type 1 diabetes mellitus (T1DM) in patients with COVID-19 have been published, denoting an association between both diseases. Therefore, we conducted this systematic review to summarize the prevalence of T1DM in COVID-19 patients and to identify the clinical presentations and outcomes in this patient population. MATERIALS AND METHODS: Up to 10/27/2020, Medline, Embase, cochrane and google scholar databases were searched for original studies investigating the association between COVID-19 and T1DM...
January 2021: Diabetes & Metabolic Syndrome
https://read.qxmd.com/read/33101821/a-clinical-challenge-in-the-emergency-department-a-case-of-klebsiella-infective-endocarditis-presenting-with-splenic-abscess
#31
Nicolas Ulloa, Jessica M Cook, Shaun Smithson
Infective endocarditis (IE) is a serious bacterial infection of the endocardium and/or heart valves that carries considerable morbidity and mortality. Often presenting with very non-specific symptoms, this disease presents many challenges to the emergency medicine practitioner. A 47-year-old male with no pertinent medical history presented to the emergency department complaining of shortness of breath. He stated that his symptoms had been persistent for the last three weeks and were associated with malaise and fatigue...
September 21, 2020: Curēus
https://read.qxmd.com/read/33088905/myocarditis-associated-with-covid-19
#32
JOURNAL ARTICLE
Filip Oleszak, Andrii Maryniak, Evan Botti, Christian Abrahim, Moro O Salifu, Mary Youssef, Victoria L Henglein, Samy I McFarlane
Coronavirus disease 2019 (COVID-19) has rapidly evolved into a global pandemic, with affecting to-date over 23 million people and causing over 800,000 deaths around the globe. The major pathogenetic mechanisms include inflammation, vasoconstriction and thrombogenesis. Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) typically manifests as fever, cough, shortness of breath, and exhibits radiographic evidence of bilateral pneumonic infiltrates. Recent meta-analyses have shown that myocardial injury, including viral myocarditis, is prevalent among infected patients, especially in patients requiring ICU level care...
2020: American Journal of Medical Case Reports
https://read.qxmd.com/read/33076968/compare-the-epidemiological-and-clinical-features-of-imported-and-local-covid-19-cases-in-hainan-china
#33
JOURNAL ARTICLE
Biao Wu, Zi-Ying Lei, Kun-Liang Wu, Jian-Rong He, Hui-Juan Cao, Juan Fu, Feng Chen, Yuan Chen, Bao Chen, Xiao-Li Zhou, Tao Huang, Tao Wu, Yong-Guo Du, Suo-Xian Chen, Fu-Rong Xiao, Zhi-Liang Gao, Jing He, Feng Lin, Bing-Liang Lin
BACKGROUND: Effective management of imported cases is an important part of epidemic prevention and control. Hainan Province, China reported 168 coronavirus disease 2019 (COVID-19), including 112 imported cases on February 19, 2020, but successfully contained the epidemic within 1 month. We described the epidemiological and clinical characteristics of COVID-19 in Hainan and compared these features between imported and local cases to provide information for other international epidemic areas...
October 19, 2020: Infectious Diseases of Poverty
https://read.qxmd.com/read/32972790/varicella-zoster-virus-meningoencephalitis-with-an-atypical-presentation-of-chest-pain-impaired-memory-and-seizure
#34
JOURNAL ARTICLE
An Nguyen, Laura Bauler, Casey Hoehn, Joshua Mastenbrook
BACKGROUND: Neurologic complications of varicella zoster virus (VZV) reactivation can be associated with considerable mortality and morbidity. Aseptic meningitis associated with VZV infection is rare, occurring in 0.5% of immunocompetent individuals. One third of VZV-related neurologic disease occurs without the classic herpes zoster exanthema, making early recognition more difficult. CASE REPORT: A 60-year-old man presented to the emergency department with chest pain and impaired memory that he attributed to a transient ischemic attack as suggested by an urgent care facility 1 day earlier...
November 2020: Journal of Emergency Medicine
https://read.qxmd.com/read/32888288/case-report-recurrent-clinical-symptoms-of-covid-19-in-healthcare-professionals-a-series-of-cases-from-brazil
#35
JOURNAL ARTICLE
Christianne Fernandes Valente Takeda, Magda Moura de Almeida, Ricristhi Gonçalves de Aguiar Gomes, Tatiana Cisne Souza, Matheus Alves de Lima Mota, Luciano Pamplona de Góes Cavalcanti, Jeová Keny Baima Colares
We describe six cases of healthcare professionals in Brazil who recovered but again presented symptoms consistent with COVID-19, with new positive reverse transcription (RT)-PCR test results. The cases reported herein presented symptom onset between March 16, 2020 and April 9, 2020. All were health professionals (four medical doctors), five were female, with a median age of 43.5 years, and three had comorbidities. All patients were confirmed for SARS-CoV-2 detection by RT-PCR in naso and/or oropharyngeal swab samples...
September 4, 2020: American Journal of Tropical Medicine and Hygiene
https://read.qxmd.com/read/32752571/cerebral-and-plasmodium-ovale-malaria-in-rhode-island
#36
JOURNAL ARTICLE
Joshua Kaine, Joseph Moran-Guiati, James Tanch, Brian Clyne
We report two cases of malaria diagnosed in Rhode Island. First, a 21-year-old female who presented with 5 days of fevers, chills, headache, and myalgias after returning from a trip to Liberia, found to have uncomplicated malaria due to P. ovale which was treated successfully with atovaquone/proguanil and primaquine. Second, a chronically ill 55-year-old male presented with 3 days of headache followed by altered mental status, fever, and new-onset seizures after a recent visit to Sierra Leone, found to have P...
August 3, 2020: Rhode Island Medical Journal
https://read.qxmd.com/read/32719205/mortality-from-acinetobacter-infections-as-compared-to-other-infections-among-critically-ill-patients-in-south-india-a-prospective-cohort-study
#37
JOURNAL ARTICLE
Ajoy Oommen John, Hema Paul, Saranya Vijayakumar, Shalini Anandan, Thomas Sudarsan, Ooriyapadickal Cherian Abraham, Veeraraghavan Balaji
Background: Acinetobacter baumannii has become a common pathogen causing hospital-acquired infections (HAIs). Although acquiring any nosocomial infection is associated with increased mortality, we do not know if the acquisition of Acinetobacter infection confers a worse prognosis as compared to non-Acinetobacter-related HAI. The aim of the current study is to compare the clinical outcomes of ventilator-associated pneumonia (VAP) and central line associated blood stream infections (CLABSIs) caused by A...
January 2020: Indian Journal of Medical Microbiology
https://read.qxmd.com/read/32694498/multiple-thrombotic-events-in-a-67-year-old-man-2-weeks-after-testing-positive-for-sars-cov-2-a-case-report
#38
JOURNAL ARTICLE
Ahmed Shawkat, Eric T Merrell, Ghada A Fadel, Ioana Amzuta, Hossam Amin, Amish J Shah, Hanan Habeb, Hani Aiash
BACKGROUND Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the viral pathogen responsible for coronavirus disease 2019 (COVID-19), a pandemic respiratory illness. While many patients experience mild to moderate symptoms, severely affected patients often progress to acute respiratory distress syndrome (ARDS). Specific to COVID-19, abnormal coagulability appears to be a principal instigator in the progression of disease severity and mortality. In this report we summarize a case of COVID-19 in which extreme thrombophilia led to patient demise...
July 22, 2020: American Journal of Case Reports
https://read.qxmd.com/read/32602676/clinical-and-epidemiological-features-of-sars-cov-2-patients-in-sari-ward-of-a-tertiary-care-centre-in-new-delhi
#39
JOURNAL ARTICLE
Amit Aggarwal, Abhinav Shrivastava, Abhinav Kumar, Adila Ali
Importance: Rapid spread of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) in Wuhan, China, prompted heightened surveillance in India. Since the first laboratory confirmed case of SARS-CoV-2 was reported from Kerala on January 30, 2020 novel coronavirus infected pneumonia (NCIP) has been presenting to the hospital emergencies as severe acute respiratory illness (SARI). We aim to find out the rate of SARS-CoV-2 positivity in SARI cases and further clarify the epidemiological and clinical characteristics of NCIP in New Delhi, India...
July 2020: Journal of the Association of Physicians of India
https://read.qxmd.com/read/32519944/the-characteristics-of-50-hospitalized-covid-19-patients-with-and-without-ards
#40
JOURNAL ARTICLE
Michael Dreher, Alexander Kersten, Johannes Bickenbach, Paul Balfanz, Bojan Hartmann, Christian Cornelissen, Ayham Daher, Robert Stöhr, Michael Kleines, Sebastian W Lemmen, Jörg Christian Brokmann, Tobias Müller, Dirk Müller-Wieland, Gernot Marx, Nikolaus Marx
BACKGROUND: The type of pneumonia (coronavirus disease 2019, COVID-19) that is caused by the new coronavirus (severe acute respiratory syndrome coronavirus 2, SARS-CoV-2) is now spreading across the world in a pandemic. Many patients with COVID-19 were admitted to the University Hospital Aachen during an outbreak that first struck the Heinsberg district in February 2020. METHODS: A comparative presentation of the clinical features of the first 50 COVID-19 patients with and without acute respiratory distress syndrome (ARDS) who were hospitalized in the University Hospital Aachen...
April 17, 2020: Deutsches Ärzteblatt International
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