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https://www.readbyqxmd.com/read/28239378/enterococcus-durans-ep1-a-promising-anti-inflammatory-probiotic-able-to-stimulate-siga-and-to-increase-faecalibacterium-prausnitzii-abundance
#1
Paula Carasi, Silvia María Racedo, Claudine Jacquot, Anne Marie Elie, María de Los Ángeles Serradell, María C Urdaci
Enterococcus species, principally Enterococcus faecium are used as probiotics since a long time with preference in animal applications but safety considerations were updated and also new uses as probiotics can be envisaged. Fifteen Enterococcus strains isolated from different foods were identified and analyzed for virulence factors and antibiotic resistance. Three Enterococcus durans strains were selected to study their immunomodulatory properties on PBMC and Caco2 cells. Two strains presented a profile toward a mild inflammatory Th1 response considering TNF-α/IL-10 and IL-1β/IL-10 cytokines ratios...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28239291/single-molecule-localization-microscopy-of-dna-damage-response-pathways-in-cancer
#2
Donna R Whelan, Yandong Yin, Keria Bermudez-Hernandez, Sarah Keegan, David Fenyö, Eli Rothenberg
No abstract text is available yet for this article.
July 2016: Microscopy and Microanalysis
https://www.readbyqxmd.com/read/28238188/microglia-activation-and-phagocytosis-relationship-with-aging-and-cognitive-impairment-in-the-rhesus-monkey
#3
Eli Shobin, Michael P Bowley, Larissa I Estrada, Nadine C Heyworth, Mary E Orczykowski, Sherri A Eldridge, Samantha M Calderazzo, Farzad Mortazavi, Tara L Moore, Douglas L Rosene
While cognitive decline is observed in the normal aging monkey, neurons are not lost with age. Instead, frontal white matter is lost as myelin degenerates and both correlate with age-related cognitive decline. As age-related myelin damage increases, there should be an increase in clearance of damaged myelin by microglial phagocytosis. In this study, brains of behaviorally tested rhesus monkeys were assessed using unbiased stereology to quantify the density of activated microglia (LN3 antibody positive) and phagocytic microglia (galectin-3 (Gal-3) antibody positive) in three white matter regions: the corpus callosum, cingulum bundle (CGB), and frontal white matter (FWM)...
February 25, 2017: Geroscience
https://www.readbyqxmd.com/read/28237697/heart-transplantation-in-adults-with-congenital-heart-disease
#4
REVIEW
Lucile Houyel, Ngoc-Tram To-Dumortier, Yannick Lepers, Jérôme Petit, Régine Roussin, Mohamed Ly, Emmanuel Lebret, Elie Fadel, Jürgen Hörer, Sébastien Hascoët
With the advances in congenital cardiac surgery and postoperative care, an increasing number of children with complex congenital heart disease now reach adulthood. There are already more adults than children living with a congenital heart defect, including patients with complex congenital heart defects. Among these adults with congenital heart disease, a significant number will develop ventricular dysfunction over time. Heart failure accounts for 26-42% of deaths in adults with congenital heart defects. Heart transplantation, or heart-lung transplantation in Eisenmenger syndrome, then becomes the ultimate therapeutic possibility for these patients...
February 22, 2017: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/28237358/audio-visual-interaction-in-visual-motion-detection-synchrony-versus-asynchrony
#5
Stephanie Rosemann, Inga-Maria Wefel, Volkan Elis, Manfred Fahle
OBJECTIVE: Detection and identification of moving targets is of paramount importance in everyday life, even if it is not widely tested in optometric practice, mostly for technical reasons. There are clear indications in the literature that in perception of moving targets, vision and hearing interact, for example in noisy surrounds and in understanding speech. The main aim of visual perception, the ability that optometry aims to optimize, is the identification of objects, from everyday objects to letters, but also the spatial orientation of subjects in natural surrounds...
February 23, 2017: Journal of Optometry
https://www.readbyqxmd.com/read/28236513/remote-management-of-low-to-intermediate-risk-chest-pain-a-case-series
#6
Alexander Chiu, Kathleen Shumaker, Christopher Del Corral, Blessy George, Michael Kasper, Elie Marie-Carmelle, Preeti Jois, Daniel Dipsia, Adam Ash
We report a case series of three low to intermediate risk chest pain patients who presented to the emergency department and were managed as outpatients via the Cellular Outpatient Twelve-Lead Telemetry with Emergency Response (COTTER™). This technology allows for certain chest pain patients to be managed remotely via telemedicine while receiving care comparable to that which would be available in a hospital or chest pain observation unit.
February 16, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28235965/electronic-nicotine-delivery-systems-and-or-electronic-non-nicotine-delivery-systems-for-tobacco-smoking-cessation-or-reduction-a-systematic-review-and-meta-analysis
#7
Regina El Dib, Erica A Suzumura, Elie A Akl, Huda Gomaa, Arnav Agarwal, Yaping Chang, Manya Prasad, Vahid Ashoorion, Diane Heels-Ansdell, Wasim Maziak, Gordon Guyatt
OBJECTIVE: A systematic review and meta-analysis to investigate the impact of electronic nicotine delivery systems (ENDS) and/or electronic non-nicotine delivery systems (ENNDS) versus no smoking cessation aid, or alternative smoking cessation aids, in cigarette smokers on long-term tobacco use. DATA SOURCES: Searches of MEDLINE, EMBASE, PsycInfo, CINAHL, CENTRAL and Web of Science up to December 2015. STUDY SELECTION: Randomised controlled trials (RCTs) and prospective cohort studies...
February 23, 2017: BMJ Open
https://www.readbyqxmd.com/read/28235893/single-neurons-in-the-avian-auditory-cortex-encode-individual-identity-and-propagation-distance-in-naturally-degraded-communication-calls
#8
Solveig C Mouterde, Julie E Elie, Nicolas Mathevon, Frédéric E Theunissen
One of the most complex tasks performed by sensory systems is "scene analysis": the interpretation of complex signals as behaviorally relevant objects. The study of this problem, universal to species and sensory modalities, is particularly challenging in audition, where sounds from various sources and localizations, degraded by propagation through the environment, sum to form a single acoustical signal. Here we investigated in a songbird model, the zebra finch, the neural substrate for ranging and identifying a single source...
February 24, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28231584/characteristics-of-sarcoidosis-in-patients-with-previous-malignancy-causality-or-coincidence
#9
Nissim Arish, Rottem Kuint, Eli Sapir, Liran Levy, Avraham Abutbul, Zvi Fridlender, Uri Laxer, Neville Berkman
BACKGROUND: The association between sarcoidosis and malignancy is poorly defined. Sarcoidosis can precede, be diagnosed concurrently with, or follow malignancy. OBJECTIVES: We describe the clinical and radiological features of patients with sarcoidosis following malignancy to determine whether this association is causal or coincidental. METHODS: We performed a search for all patients with confirmed sarcoidosis following malignancy in our institution during 2001-2015...
February 24, 2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/28230970/the-role-of-air-electrode-structure-on-the-incorporation-of-immiscible-pfcs-in-non-aqueous-li-o2-battery
#10
Moran Balaish, Yair Ein-Eli
Perfluorocrbons (PFCs) are considered advantageous additives to non-aqueous Li-O2 battery due to their superior oxygen solubility and diffusivity compared to common battery electrolytes. Up to now, the main focus was concentrated on PFCs-electrolyte investigation, however no special attention was granted to the role of carbon structure in the PFCs- Li-O2 system. Immiscible PFCs, rather than miscible fluorinated-ethers, were added to activated-carbon class air-electrode due to their higher susceptibility towards attack and to their ability to shift the reaction from two phase to an artificial three phase reaction zone...
February 23, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28230450/characteristics-and-medication-use-of-psoriasis-patients-who-may-or-may-not-qualify-for-randomized-controlled-trials
#11
William Malatestinic, Beth Nordstrom, Jashin J Wu, Orin Goldblum, Kathleen Solotkin, Chen-Yen Lin, Kristin Kistler, Kathy Fraeman, Joseph Johnston, Lcdr Lesley Hawley, Nicholas Sicignano, Andre Araujo
BACKGROUND: Clinical trials impose exclusion criteria that may limit the generalizability of results. OBJECTIVES: To (a) determine the percentage of real-world patients who would qualify for psoriasis randomized controlled trials; (b) ascertain differences between moderate-to-severe psoriasis patients who would be eligible, ineligible, or potentially eligible for clinical trials; and (c) compare their biologic treatment patterns. METHODS: Moderate-to-severe psoriasis patients were identified from the U...
March 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28230446/economic-impact-of-treatment-duration-and-persistence-with-basal-insulin-in-previously-insulin-naive-users
#12
Samaneh Kalirai, Ran Duan, Dongju Liu, Beverly L Reed
BACKGROUND: Although insulin is a well-established therapy that is associated with improved clinical outcomes, adherence and persistence with insulin regimens are poor in patients with type 2 diabetes mellitus (T2DM). Diabetes-related health care costs and the impact of insulin persistence patterns on these health care costs have been previously studied; however, these aspects of insulin therapy have limited data beyond the first year of use and have not been characterized among patients previously naive to basal insulin...
March 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28228142/change-in-anopheles-richness-and-composition-in-response-to-artificial-flooding-during-the-creation-of-the-jirau-hydroelectric-dam-in-porto-velho-brazil
#13
Moreno S Rodrigures, Elis P Batista, Alexandre A Silva, Fábio M Costa, Verissimo A S Neto, Luiz Herman S Gil
BACKGROUND: Anopheles mosquitoes are the only vectors of human malaria. Anopheles species use standing water as breeding sites. Human activities, like the creation of an artificial lake during the implementation of hydroelectric power plants, lead to changes in environmental characteristics and, therefore, may changes the species richness and composition of Anopheles mosquitoes. The aim of the present study was to verify whether or not there is an association between the artificial flooding resulting from the construction of the Jirau hydroelectric power plant, and the richness and composition of anophelines...
February 22, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28227384/automatic-classification-of-cancer-cells-in-multispectral-microscopic-images-of-lymph-node-samples
#14
Gali Zimmerman-Moreno, Irina Marin, Moshe Lindner, Iris Barshack, Yuval Garini, Eli Konen, Arnaldo Mayer, Gali Zimmerman-Moreno, Irina Marin, Moshe Lindner, Iris Barshack, Yuval Garini, Eli Konen, Arnaldo Mayer, Moshe Lindner, Yuval Garini, Gali Zimmerman-Moreno, Arnaldo Mayer, Eli Konen, Iris Barshack, Irina Marin
Histopathological analysis is crucial for the diagnosis of a large number of cancer types. A lot of progress has been made in the development of molecular based assays, but many of the cases still require the careful analysis of the stained tissue under a bright-field microscope and its analysis. This procedure is costly and time-consuming. We present a novel method for classification of cancer cells in lymph node images. It is based on the measurement of the spectral image of hematoxylin and eosin stained sample under the microscope and the analysis of the acquired data using state of the art machine learning techniques...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227361/kinect2-respiratory-movement-detection-study
#15
Sandy Rihana, Elie Younes, Dimitris Visvikis, Hadi Fayad, Sandy Rihana, Elie Younes, Dimitris Visvikis, Hadi Fayad, Sandy Rihana, Elie Younes, Dimitris Visvikis, Hadi Fayad
Radiotherapy is one of the main cancer treatments. It consists in irradiating tumor cells to destroy them while sparing healthy tissue. The treatment is planned based on Computed Tomography (CT) and is delivered over fractions during several days. One of the main challenges is replacing patient in the same position every day to irradiate the tumor volume while sparing healthy tissues. Many patient positioning techniques are available. They are both invasive and not accurate performed using tattooed marker on the patient's skin aligned with a laser system calibrated in the treatment room or irradiating using X-ray...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28225290/screenpro-fh-screening-project-for-familial-hypercholesterolemia-in-central-southern-and-eastern-europe-rationale-and-design
#16
Richard Češka, György Paragh, Željko Reiner, Maciej Banach, Lale Tokgözoğlu, Andrey V Susekov, Katarína Rašlová, Tomáš Freiberger, Branislav Vohnout, Andrzej Rynkiewicz, Assen Goudev, Gheorghe-Andrei Dan, Dan Gaiţă, Belma Pojskić, Ivan Pećin, Meral Kayıkçıoğlu, Olena Mitchenko, Marat V Ezhov, Gustavs Latkovskis, Žaneta Petrulionienė, Zlatko Fras, Nebojsa Tasić, Erkin M Mirrakhimov, Tolkun Murataliev, Alexander B Shek, Vladimír Tuka, Alexandros D Tselepis, Elie M Moubarak, Khalid Al Rasadi
Familial hypercholesterolemia (FH) is a genetic disorder with well-known genetic transmission and clinical course. Despite great recent progress, FH is still underestimated, under-diagnosed and thus undertreated. Furthermore it represents a significant healthcare challenge as a common risk factor for the premature development of coronary heart disease. The ScreenPro FH Project is an international network project aiming at improving complex care - from timely screening, through diagnosis to up-to-date treatment of familial hypercholesterolemia in Central, Eastern and Southern Europe...
2017: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/28225288/screenpro-fh-screening-project-for-familial-hypercholesterolemia-in-central-southern-and-eastern-europe-basic-epidemiology
#17
Richard Češka, Tomáš Freiberger, Andrey V Susekov, György Paragh, Željko Reiner, Lale Tokgözoğlu, Katarína Rašlová, Maciej Banach, Branislav Vohnout, Andrzej Rynkiewicz, Assen Goudev, Gheorghe-Andrei Dan, Dan Gaiţă, Belma Pojskić, Ivan Pećin, Meral Kayıkçıoğlu, Olena Mitchenko, Marat V Ezhov, Gustavs Latkovskis, Žaneta Petrulionienė, Zlatko Fras, Nebojsa Tasić, Erkin M Mirrakhimov, Tolkun Murataliev, Alexander B Shek, Vladimír Tuka, Alexandros D Tselepis, Elie M Moubarak, Khalid Al Rasadi
INTRODUCTION: Despite great recent progress, familial hypercholesterolemia (FH) is still underestimated, under-diagnosed and thus undertreated worldwide. We have very little information on exact prevalence of patients with FH in the Central, Eastern and Southern Europe (CESE) region. The aim of the study was to describe the epidemiological situation in the CESE region from data available. METHODS: All local leaders of the ScreenPro FH project were asked to provide local data on (a) expert guess of FH prevalence (b) the medical facilities focused on FH already in place (c) the diagnostic criteria used (d) the number of patients already evidenced in local database and (e) the availability of therapeutic options (especially plasma apheresis)...
2017: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/28224019/database-fingerprint-dfp-an-approach-to-represent-molecular-databases
#18
Eli Fernández-de Gortari, César R García-Jacas, Karina Martinez-Mayorga, José L Medina-Franco
BACKGROUND: Molecular fingerprints are widely used in several areas of chemoinformatics including diversity analysis and similarity searching. The fingerprint-based analysis of chemical libraries, in particular of large collections, usually requires the molecular representation of each compound in the library that may lead to issues of storage space and redundant calculations. In fact, information redundancy is inherent to the data, resulting on binary digit positions in the fingerprint without significant information...
2017: Journal of Cheminformatics
https://www.readbyqxmd.com/read/28222277/antibiotic-prophylaxis-in-blepharoplasty-review-of-the-current-literature
#19
REVIEW
Elie M Ferneini, Steven Halepas, Steven I Aronin
The purpose of this study was to provide an evidence-based overview of antibiotic prophylaxis in blepharoplasty. We performed a literature search that evaluated the risk of infection associated with blepharoplasty, as well as the risks and benefits of antibiotic prophylaxis. The overall infection rate associated with eyelid surgery is extremely low. However, the use of antibiotic prophylaxis has increased over the past 25 years in esthetic facial procedures. There is no standard of care for or against antibiotic prophylaxis, and routine practices vary widely...
February 1, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28219483/family-impairment-associated-with-childhood-obsessive-compulsive-disorder
#20
EDITORIAL
Eli R Lebowitz
No abstract text is available yet for this article.
March 2017: Journal of the American Academy of Child and Adolescent Psychiatry
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