Read by QxMD icon Read


Clara Helena González-Correa, Julio César Caicedo-Eraso
BACKGROUND: The accuracy and precision of the BIA method is affected by the electrode system. Failing to adjust for differences in it may result in systematic biases of up to 5.2%. METHODS: Forty females ranging from 18 to 24 years, with a body mass index (BMI) of 18.6 to 27.6 kg/m2, were measured by BIA in the frequency range 5 to 500 kHz using the manufacturers recommended electrodes and two types of commercial ECG electrodes (3M-2228 and 3M-2330). RESULTS: The two types of ECG electrodes performed well, but at high frequencies 2330 performed better...
January 16, 2018: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
L Daniel Maxim, Mark J Utell
This literature review on refractory ceramic fibers (RCF) summarizes relevant information on manufacturing, processing, applications, occupational exposure, toxicology and epidemiology studies. Rodent toxicology studies conducted in the 1980s showed that RCF caused fibrosis, lung cancer and mesothelioma. Interpretation of these studies was difficult for various reasons (e.g. overload in chronic inhalation bioassays), but spurred the development of a comprehensive product stewardship program under EPA and later OSHA oversight...
March 22, 2018: Inhalation Toxicology
Eva Králíková
Half a century of lying, an eighteen-year litigation, and an eleven-year disagreement with few words - to sum up a media campaign forced on cigarette manufacturers in the US at the turn of 2017/2018. In the given media, in the given extent and at the given frequency, they are forced to publish an apology for public lying with an impact on human health and lives.
2018: Casopís Lékar̆ů C̆eských
Mei Wang, Ya Tang, Christopher W N Anderson, Paramsothy Jeyakumar, Jinyan Yang
Contamination of soil and water with fluorine (F) leached from phosphogypsum (PG) stacks is a global environmental issue. Millions of tons of PG is produced each year as a by-product of fertilizer manufacture, and in China, weathering is exacerbated by acid rain. In this work, column leaching experiments using simulated acid rain were run to evaluate the mobility of F and the impact of weathering on native bacterial community composition in PG. After a simulated summer rainfall, 2.42-3.05 wt% of the total F content of PG was leached and the F concentration in leachate was above the quality standard for surface water and groundwater in China...
March 21, 2018: Environmental Science and Pollution Research International
Yuanli Luo, Daiwen Dong, Yu Su, Xuyi Wang, Yumei Peng, Jiang Peng, Changyong Zhou
Mustard clubroot, caused by Plasmodiophora brassicae, is a serious disease that affects Brassica juncea var. tumida Tsen, a mustard plant that is the raw material for a traditional fermented food manufactured in Chongqing, China. In our laboratory, we screened the antagonistic bacteria Zhihengliuella aestuarii against P. brassicae. To better understand the biocontrol mechanism, three transcriptome analyses of B. juncea var. tumida Tsen were conducted using Illumina HiSeq 4000, one from B. juncea only inoculated with P...
March 22, 2018: Functional & Integrative Genomics
Valentin Jossen, Christian van den Bos, Regine Eibl, Dieter Eibl
Human mesenchymal stem cell (hMSC)-based therapies are of increasing interest in the field of regenerative medicine. As economic considerations have shown, allogeneic therapy seems to be the most cost-effective method. Standardized procedures based on instrumented single-use bioreactors have been shown to provide billion of cells with consistent product quality and to be superior to traditional expansions in planar cultivation systems. Furthermore, under consideration of the complex nature and requirements of allogeneic hMSC-therapeutics, a new equipment for downstream processing (DSP) was successfully evaluated...
March 22, 2018: Applied Microbiology and Biotechnology
Andrew M Hill, Melissa J Barber, Dzintars Gotham
Introduction: There are persistent gaps in access to affordable medicines. The WHO Model List of Essential Medicines (EML) includes medicines considered necessary for functional health systems. Methods: A generic price estimation formula was developed by reviewing published analyses of cost of production for medicines and assuming manufacture in India, which included costs of formulation, packaging, taxation and a 10% profit margin. Data on per-kilogram prices of active pharmaceutical ingredient exported from India were retrieved from an online database...
2018: BMJ Global Health
Soon Woo Park, Young Joong Kang, Huisu Eom, Hyun-Jin Cho, Jungho Ahn, Sang-Gil Lee
Background: The olfactory bulb is anatomically exposed and thus can be directly damaged by external stimulation. This can occur as an occupational injury owing to contact with organic solvents or other causes. We present cases of eight patients who sustained occupation-related exposure to potentially toxic substances and later presented with signs and symptoms of anosmia. We examined the occupational and medical characteristics of the patients and evaluated their work-relatedness. Case presentation: Case 1: A 50-year-old man performed high-frequency heat treatments for approximately 11 years...
2018: Annals of Occupational and Environmental Medicine
Abdullah Akgun, Fehmi Yazici, Haci Ali Gulec
The combined effects of starter culture type (SCT) and incubation final pH (IFpH) on the physicochemical and organoleptic properties of buffalo milk yogurt containing 3 g·100 g-1 milk fat were investigated throughout 20 days of storage at 4°C. The postacidification kinetics fitted to zero-order reaction for all buffalo milk yogurt samples. The reaction rate constants of the buffalo milk yogurt samples containing YC-X11, ABY-2, and ABT-4 cultures were 0.010, 0.007, and 0.004 g·100 g-1 ·day-1 , respectively...
March 2018: Food Science & Nutrition
Lukumon A Odunmbaku, Sunday S Sobowale, Monilola K Adenekan, Taiwo Oloyede, Janet A Adebiyi, Oluwafemi A Adebo
The quest for high-quality starch that would meet the needs of manufacturers is ever increasing. This study investigated the effect of steeping duration, drying temperature, and duration on the chemical properties of sorghum starch, to possibly alter the characteristics of sorghum starch for food applications. Steeping duration, drying temperature, and drying time of starch isolation were optimized using a central composite design and nine parameters including pH, amylose content, moisture, protein, ash, crude fiber, fat, carbohydrate, and total energy determined...
March 2018: Food Science & Nutrition
David Glineur, Marc Hendrikx, Dainis Krievins, Peteris Stradins, Bernhard Voss, Thomas Waldow, Luc Haenen, Martin Oberhoffer, Caroline M Ritchie
Background: Obtaining hemostasis during cardiovascular procedures can be a challenge, particularly around areas with a complex geometry or that are difficult to access. While several topical hemostats are currently on the market, most have caveats that limit their use in certain clinical scenarios such as pulsatile arterial bleeding. The aim of this study was to assess the effectiveness and safety of Veriset™ hemostatic patch in treating cardiovascular bleeding. Methods: Patients (N=90) scheduled for cardiac or vascular surgery at 12 European institutions were randomized 1:1 to treatment with either Veriset™ hemostatic patch (investigational device) or TachoSil® (control)...
2018: Medical Devices: Evidence and Research
Deepti Sachan, S Aswin Kumar
Drug-dependent antibodies can rarely cause interference in pretransfusion antibody screening. The diluents for commercial reagent red blood cells contain different antibiotics, such as chloramphenicol, neomycin sulfate, and gentamycin as a preservative. The presence of antibodies to a given drug in patient may lead to positive results when performing antibody identification. We present a rare case of detection of anti-co-trimoxazole antibody during routine antibody screening in a female patient undergoing neurosurgery...
January 2018: Asian Journal of Transfusion Science
T J Lutz, P T Bissert, G T Homce, J A Yonkey
Underground refuge alternatives require an air source to supply breathable air to the occupants. This requires pressure relief valves to prevent unsafe pressures from building up within the refuge alternative. The U.S. Mine Safety and Health Administration (MSHA) mandates that pressure relief valves prevent pressure from exceeding 1.25 kPa (0.18 psi), or as specified by the manufacturer, above mine atmospheric pressure when a fan or compressor is used for the air supply. The U.S. National Institute for Occupational Safety and Health (NIOSH) tested a variety of pressure relief valves using an instrumented test fixture consisting of data acquisition equipment, a centrifugal blower, ductwork and various sensors to determine if the subject pressure relief valves meet the MSHA requirement...
March 2018: Mining Engineering
Karel Lietaert, Antonio Cutolo, Dries Boey, Brecht Van Hooreweder
Mechanical performance of additively manufactured (AM) Ti6Al4V scaffolds has mostly been studied in uniaxial compression. However, in real-life applications, more complex load conditions occur. To address this, a novel sample geometry was designed, tested and analyzed in this work. The new scaffold geometry, with porosity gradient between the solid ends and scaffold middle, was successfully used for quasi-static tension, tension-tension (R = 0.1), tension-compression (R = -1) and compression-compression (R = 10) fatigue tests...
March 21, 2018: Scientific Reports
Bogna Stawarczyk, Nina Lümkemann, Marlis Eichberger, Timea Wimmer
The purpose of this investigation was to analyze the accuracy of digitally fabricated wax trial dentures and conventionally finalized complete dentures in comparison to a surface tessellation language (STL)-dataset. A generated data set for the denture bases and the tooth sockets was used, converted into STL-format, and saved as reference. Five mandibular and 5 maxillary denture bases were milled from wax blanks and denture teeth were waxed into their tooth sockets. Each complete denture was checked on fit, waxed onto the dental cast, and digitized using an optical laboratory scanning device...
December 19, 2017: Dent J (Basel)
Noritoshi Fukushima, Makiko Kitabayashi, Hiroyuki Kikuchi, Hiroyuki Sasai, Koichiro Oka, Yoshio Nakata, Shigeho Tanaka, And Shigeru Inoue
OBJECTIVE: The times spent in sedentary behavior (SB) and moderate-to-vigorous physical activity (MVPA) are independently associated with health outcomes; however, objective data on physical activity levels including SB among different occupations is limited. We compared accelerometer-measured times spent in SB, light-intensity physical activity (LPA), and MVPA, and the patterns associated with prolonged bouts of SB between white- and blue-collar workers. METHODS: The study population consisted of 102 full-time plant workers (54 white-collar and 48 blue-collar) who wore a triaxial accelerometer during waking hours for 5 working days...
March 20, 2018: Journal of Occupational Health
Ichiro Higashikubo, Heihachiro Arito, Kenji Ando, Akihiro Araki, Hidesuke Shimizu, Haruhiko Sakurai
OBJECTIVES: This study aimed to assess workers' exposure to indium and its compounds in 55 indium-handling operations among 13 Japanese plants. The surveyed plants were selected from indium-manufacturing plants whose annual indium production exceeded 500 kg. METHODS: The Control of Substances Hazardous to Health (COSHH) Essentials control banding toolkit, which contains simple scales for hazard levels, quantities in daily use, and "dustiness" characteristics, was used to assess generic risks of indium-handling operations...
March 20, 2018: Journal of Occupational Health
Hyunhee Ahn, Ravi R Patel, Anthony J Hoyt, Angela S P Lin, F Brennan Torstrick, Robert E Guldberg, Carl P Frick, R Dana Carpenter, Christopher M Yakacki, Nick J Willett
Poly(para-phenylene) (PPP) is a novel aromatic polymer with higher strength and stiffness than polyetheretherketone (PEEK), the gold standard material for polymeric load-bearing orthopaedic implants. The amorphous structure of PPP makes it relatively straightforward to manufacture different architectures, while maintaining mechanical properties. PPP is promising as a potential orthopaedic material; however, the biocompatibility and osseointegration have not been well investigated. The objective of this study was to evaluate biological and mechanical behavior of PPP, with or without porosity, in comparison to PEEK...
March 18, 2018: Acta Biomaterialia
Cyril Jacquot, Meghan Delaney
The US blood supply has never been safer. This level of safety depends on a multifaceted approach including blood donor screening, sensitive infectious disease testing, and good manufacturing practice. However, risks remain for transfusion-transmitted infections due to bacterial contamination of platelets and emerging diseases. Thus, ongoing improvements in screening and testing are required. Newer pathogen reduction technologies have shown promise in further ameliorating the safety of the blood supply.
January 1, 2018: Journal of Intensive Care Medicine
Noa Sher, Racheli Ofir
The ephemeral placenta provides a noncontroversial source of young, healthy cells of both maternal and fetal origin from which cell therapy products can be manufactured. The 2 advantages of using live cells as therapeutic entities are: (a) in their environmental-responsive, multifactorial secretion profile and (b) in their activity as a "slow-release drug delivery system," releasing secretions over a long time frame. A major difficulty in translating cell therapy to the clinic involves challenges of large-scale, robust manufacturing while maintaining product characteristics, identity, and efficacy...
January 2018: Cell Transplantation
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"