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https://www.readbyqxmd.com/read/28735156/adaptive-periodic-paralysis-allows-weaning-deep-sedation-overcoming-the-drowning-syndrome-in-ecmo-patients-bridged-for-lung-transplantation-a-case-series
#1
Irina Timofte, Michael Terrin, Erik Barr, June Kim, Joseph Rinaldi, Nicholas Ladikos, Jay Menaker, Ali Tabatabai, Zachary Kon, Bartley Griffith, Richard Pierson, Si Pham, Aldo Iacono, Daniel Herr
PURPOSE: Sedation in extracorporeal membrane oxygenation (ECMO) is challenging. Patients require deep sedation because of extremely high respiratory rates and increased work of breathing ("Drowning Syndrome") resulting in altered intra-thoracic pressure and reduced pump flow associated with hemodynamic compromise and decreased oxygenation. However, deep sedation impedes essential active rehabilitation with physical therapy. METHODS: We reviewed data on 3 ECMO patients for whom we used a novel approach to replace continuous drips with periodic sedation/paralysis...
July 17, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28728893/-%C3%A2-2015-revised-utstein-style-recommended-guidelines-for-uniform-reporting-of-data-from-drowning-related-resuscitation-an-ilcor-advisory-statement
#2
Ahamed H Idris, Joost J L M Bierens, Gavin D Perkins, Volker Wenzel, Vinay Nadkarni, Peter Morley, David S Warner, Alexis Topjian, Allart M Venema, Christine M Branche, David Szpilman, Luiz Morizot-Leite, Masahiko Nitta, Bo Løfgren, Jonathon Webber, Jan-Thorsten Gräsner, Stephen B Beerman, Chun Song Youn, Ulrich Jost, Linda Quan, Cameron Dezfulian, Anthony J Handley, Mary Fran Hazinski
BACKGROUND: Utstein-style guidelines use an established consensus process, endorsed by the international resuscitation community, to facilitate and structure resuscitation research and publication. The first "Guidelines for Uniform Reporting of Data From Drowning" were published over a decade ago. During the intervening years, resuscitation science has advanced considerably, thus making revision of the guidelines timely. In particular, measurement of cardiopulmonary resuscitation elements and neurological outcomes reporting have advanced substantially...
June 23, 2017: Resuscitation
https://www.readbyqxmd.com/read/28719478/a-review-of-nonfatal-drowning-in-the-pediatric-age-group-a-10-year-experience-at-a-university-hospital-in-saudi-arabia
#3
Faisal O Al-Qurashi, Abdullah A Yousef, Abdullah Aljoudi, Saleh M Alzahrani, Nasser Y Al-Jawder, Abdulrahman K Al-Ahmar, Mosab S Al-Majed, Hussam M Abouollo
OBJECTIVE: The aim of this study was to evaluate the nonfatal drowning experience, risk factors, intrahospital assessment and postincidental outcomes for children admitted to King Fahd Hospital of the University, AlKhobar, Saudi Arabia, over a 10-year period. METHODS: Children up to the age of 14 years who were admitted with the diagnosis of nonfatal drowning from July 2005 to June 2015 were included. Data regarding demographics, timing, season and location of drowning, presence of an assigned lifeguard, duration of submersion and transport to hospital, cardiopulmonary resuscitation, initial Glasgow Coma Scale, temperature, pH, blood sugar level, total hospital stay, and discharge status were extrapolated, and their effects on the patient's outcome analyzed...
July 17, 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/28716971/2015-revised-utstein-style-recommended-guidelines-for-uniform-reporting-of-data-from-drowning-related-resuscitation-an-ilcor-advisory-statement
#4
REVIEW
Ahamed H Idris, Joost J L M Bierens, Gavin D Perkins, Volker Wenzel, Vinay Nadkarni, Peter Morley, David S Warner, Alexis Topjian, Allart M Venema, Christine M Branche, David Szpilman, Luiz Morizot-Leite, Masahiko Nitta, Bo Løfgren, Jonathon Webber, Jan-Thorsten Gräsner, Stephen B Beerman, Chun Song Youn, Ulrich Jost, Linda Quan, Cameron Dezfulian, Anthony J Handley, Mary Fran Hazinski
BACKGROUND: Utstein-style guidelines use an established consensus process, endorsed by the international resuscitation community, to facilitate and structure resuscitation research and publication. The first "Guidelines for Uniform Reporting of Data From Drowning" were published over a decade ago. During the intervening years, resuscitation science has advanced considerably, thus making revision of the guidelines timely. In particular, measurement of cardiopulmonary resuscitation elements and neurological outcomes reporting have advanced substantially...
July 2017: Circulation. Cardiovascular Quality and Outcomes
https://www.readbyqxmd.com/read/28716352/fatal-and-non-fatal-injury-outcomes-results-from-a-purposively-sampled-census-of-seven-rural-subdistricts-in-bangladesh
#5
Olakunle Alonge, Priyanka Agrawal, Abu Talab, Qazi S Rahman, Akm Fazlur Rahman, Shams El Arifeen, Adnan A Hyder
BACKGROUND: 90% of the global burden of injuries is borne by low-income and middle-income countries (LMICs). However, details of the injury burden in LMICs are less clear because of the scarcity of data and population-based studies. The Saving of Lives from Drowning project, implemented in rural Bangladesh, did a census on 1·2 million people to fill this gap. This Article describes the epidemiology of fatal and non-fatal injuries from the study. METHODS: In this study, we used data from the baseline census conducted as part of the Saving of Lives from Drowning (SoLiD) project...
August 2017: Lancet Global Health
https://www.readbyqxmd.com/read/28716063/the-use-of-non-uniform-drowning-terminology-a-follow-up-study
#6
Andrew C Schmidt, Justin R Sempsrott, David Szpilman, Ana Catarina Queiroga, Matt S Davison, Ryan J Zeigler, Sean J McAlister
BACKGROUND: In 2002, the World Congress on Drowning developed a uniform definition for drowning. The aim of this study is to determine the prevalence of "non-uniform drowning terminology" (NUDT) and "non-uniform drowning definitions" (NUDD) in peer-reviewed scientific literature from 2010 to 2016, and compare these findings with those from our unpublished study performing a similar analysis on literature from 2003 to 2010. METHODS: A systematic review was performed using drowning-specific search terms in Pubmed and Web of Science...
July 17, 2017: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
https://www.readbyqxmd.com/read/28716017/impact-of-injury-related-mortality-on-life-expectancy-in-zhejiang-china-based-on-death-and-population-surveillance-data
#7
Fang-Rong Fei, Jie-Ming Zhong, Min Yu, Wei-Wei Gong, Meng Wang, Jin Pan, Hai-Bin Wu, Ru-Ying Hu
BACKGROUND: Life expectancy is a statistical measure of the average time an organism is expected to live. The purpose of this study was to evaluate the impact of injury-related mortality on life expectancy in Zhejiang Province. METHODS: Our study used standard life tables to calculate life expectancy and cause-removed life expectancy based on mortality data from the Zhejiang Chronic Disease Surveillance System. RESULTS: Life expectancy of residents in Zhejiang was 77...
July 17, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28708115/crystal-structure-analysis-of-the-first-discovered-stability-enhanced-solid-state-of-tenofovir-disoproxil-free-base-using-single-crystal-x-ray-diffraction
#8
Ji-Hun An, Alice Nguvoko Kiyonga, Woojin Yoon, Hyung Chul Ryu, Jae-Sun Kim, Chaeri Kang, Minho Park, Hoseop Yun, Kiwon Jung
Tenofovir disoproxil (TD), an anti-virus drug, is currently marketed under its most stable form, Form-I of Tenofovir disoproxil fumarate (TDF). However, studies regarding the properties of TD free base crystal as a promising drug as well as its crystal structure have not yet been reported. This assumption was made because TD free base is not directly produced in a solid form during the manufacturing process. TD free base is first obtained in an oil form, and is then synthesized into TDF crystal. In this regard, the present study was conducted to investigate both the potentiality of TD free base to be an active pharmaceutical ingredient (API) and its crystal structure...
July 14, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28704972/impact-of-first-aid-on-treatment-outcomes-for-non-fatal-injuries-in-rural-bangladesh-findings-from-an-injury-and-demographic-census
#9
Dewan Md Emdadul Hoque, Md Irteja Islam, Shumona Sharmin Salam, Qazi Sadeq-Ur Rahman, Priyanka Agrawal, Aminur Rahman, Fazlur Rahman, Shams El-Arifeen, Adnan A Hyder, Olakunle Alonge
Non-fatal injuries have a significant impact on disability, productivity, and economic cost, and first-aid can play an important role in improving non-fatal injury outcomes. Data collected from a census conducted as part of a drowning prevention project in Bangladesh was used to quantify the impact of first-aid provided by trained and untrained providers on non-fatal injuries. The census covered approximately 1.2 million people from 7 sub-districts of Bangladesh. Around 10% individuals reported an injury event in the six-month recall period...
July 12, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28701104/a-document-analysis-of-drowning-prevention-education-resources-in-the-united-states
#10
Adam Bradley Katchmarchi, Andrea R Taliaferro, Hannah Joy Kipfer
There have been long-standing calls to better educate the public at large on risks of drowning; yet limited evaluation has taken place on current resources in circulation. The purpose of this qualitative research is to develop an understanding of the content in currently circulated drowning prevention resources in the United States. Data points (n = 451) consisting of specific content within 25 different drowning prevention educational resources were analyzed using document analysis methods; a grounded theory approach was employed to allow for categorical development and indexing of the data...
July 13, 2017: International Journal of Injury Control and Safety Promotion
https://www.readbyqxmd.com/read/28693857/how-not-to-drown-in-data-a-guide-for-biomaterial-engineers
#11
REVIEW
Aliaksei S Vasilevich, Aurélie Carlier, Jan de Boer, Shantanu Singh
High-throughput assays that produce hundreds of measurements per sample are powerful tools for quantifying cell-material interactions. With advances in automation and miniaturization in material fabrication, hundreds of biomaterial samples can be rapidly produced, which can then be characterized using these assays. However, the resulting deluge of data can be overwhelming. To the rescue are computational methods that are well suited to these problems. Machine learning techniques provide a vast array of tools to make predictions about cell-material interactions and to find patterns in cellular responses...
August 2017: Trends in Biotechnology
https://www.readbyqxmd.com/read/28682941/reduction-in-mortality-rates-of-postinjury-multiple-organ-dysfunction-syndrome-a-shifting-paradigm-a-prospective-population-based-cohort-study
#12
Karlijn J P van Wessem, Luke P H Leenen
INTRODUCTION: The incidence of Multiple Organ Dysfunction Syndrome (MODS) has decreased in the last decade by improvement in trauma care. However, it still remains a major cause of morbidity and mortality. This study investigated the current incidence and mortality of MODS in polytrauma patients. MATERIALS AND METHODS: A 3-year prospective study included consecutive trauma patients admitted to a Level-1 Trauma Center ICU. Isolated head injuries, drowning, asphyxiation and burns were excluded...
July 4, 2017: Shock
https://www.readbyqxmd.com/read/28678659/drowning-prevention-a-key-concern-for-researchers-and-major-health-bodies
#13
Samuel N Forjuoh
No abstract text is available yet for this article.
July 5, 2017: International Journal of Injury Control and Safety Promotion
https://www.readbyqxmd.com/read/28670770/are-drowned-donors-marginal-donors-a-single-pediatric-center-experience
#14
Kayla R Kumm, N Thao N Galván, Sarah Koohmaraie, Abbas Rana, Michael Kueht, Katherine Baugh, Liu Hao, Dor Yoeli, Ronald Cotton, Christine A O'Mahony, John A Goss
Drowning, a common cause of death in the pediatric population, is a potentially large donor pool for OLT. Anecdotally, transplant centers have deemed these organs high risk over concerns for infection and graft dysfunction. We theorized drowned donor liver allografts do not portend worse outcomes and therefore should not be excluded from the donation pool. We reviewed our single-center experience of pediatric OLTs between 1988 and 2015 and identified 33 drowned donor recipients. These OLTs were matched 1:2 to head trauma donor OLTs from our center...
July 3, 2017: Pediatric Transplantation
https://www.readbyqxmd.com/read/28665528/trauma-hazards-in-children-an-update-for-the-busy-clinician
#15
REVIEW
Andrew Ja Holland, Soundappan Sv Soundappan
Trauma and injury continue to be common in children and remain an important cause of mortality and morbidity. Legislation mandating the use of helmets for all cyclists appears to have been effective in reducing the incidence and severity of head and facial injuries, with no clear evidence of a reduction in cycling usage or activity. Straddle injuries, whilst uncommon and generally minor, require careful clinical assessment as they may be associated with urethral trauma. Quad bikes remain highly dangerous with continuing reports of deaths in child riders due to their inherent lack of stability: a ban on their use by children would seem the most effective solution...
June 30, 2017: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/28662311/complex-suicide-by-self-stabbing-and-drowning-a-case-report-and-a-review-of-literature
#16
Pierre-Antoine Peyron, Thierry Casper, Olivier Mathieu, Yuri Musizzano, Eric Baccino
Sharp force injuries and drowning are methods exceptionally combined in complex suicides. We report a challenging case of complex suicide by self-stabbing and drowning that illustrates the difficulty in discriminating between homicide and suicide in such circumstances of death. The corpse of a young man was found submerged in a river, stabbed nine times with two wounds that had penetrated the thorax and had caused lung injuries and a hemopneumothorax. The postmortem and histological examinations were consistent with a death caused by drowning, but the manner of death still remained undetermined...
June 29, 2017: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/28649485/scedosporium-apiospermum-brain-abscesses-in-a-patient-after-near-drowning-a-case-report-with-10-year-follow-up-and-a-review-of-the-literature
#17
Sandra C Signore, Christoph P Dohm, Gunther Schütze, Mathias Bähr, Pawel Kermer
Scedosporium apiospermum is known to be a fungal pathogen affecting immunocompromised as well as non-immunodeficient patients. Although this fungus is found rarely, an infection can lead to severe and even fatal disease. Here, we describe the case of a 41-year-old female who developed multiple Scedosporium apiospermum brain abscesses after near-drowning with aspiration of contaminated mud and water. She showed various neurological symptoms. The patient recovered after removal of abscesses in combination with long-term antifungal treatment...
September 2017: Medical Mycology Case Reports
https://www.readbyqxmd.com/read/28642385/drowned-wildebeest-provide-ecological-feast
#18
Elizabeth Pennisi
No abstract text is available yet for this article.
June 23, 2017: Science
https://www.readbyqxmd.com/read/28632035/a-comprehensive-study-of-worldwide-selfie-related-accidental-mortality-a-growing-problem-of-the-modern-society
#19
Mohit J Jain, Kinjal J Mavani
Since Oxford dictionary has described 'Selfie', selfie deaths have received a fair amount of coverage but the extent of the problem and the data behind it have not been appropriately explored. The aim of our study is to obtain epidemiological characteristics of selfie-related mortality worldwide with the objective of providing an insight to 'Why selfie', 'Why risky', 'Psychological basis' and 'measures of control.' Despite thousands of web pages, very few scientific articles are available in medical journals...
February 14, 2017: International Journal of Injury Control and Safety Promotion
https://www.readbyqxmd.com/read/28630330/annual-mass-drownings-of-the-serengeti-wildebeest-migration-influence-nutrient-cycling-and-storage-in-the-mara-river
#20
Amanda L Subalusky, Christopher L Dutton, Emma J Rosi, David M Post
The annual migration of ∼1.2 million wildebeest (Connochaetes taurinus) through the Serengeti Mara Ecosystem is the largest remaining overland migration in the world. One of the most iconic portions of their migration is crossing of the Mara River, during which thousands drown annually. These mass drownings have been noted, but their frequency, size, and impact on aquatic ecosystems have not been quantified. Here, we estimate the frequency and size of mass drownings in the Mara River and model the fate of carcass nutrients through the river ecosystem...
June 19, 2017: Proceedings of the National Academy of Sciences of the United States of America
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