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cerebrospinal fluid drainage

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https://www.readbyqxmd.com/read/29153063/-investigation-of-various-virulence-factors-of-klebsiella-pneumoniae-strains-isolated-from-nosocomial-infections
#1
Halit Kuş, Uğur Arslan, Hatice Türk Dağı, Duygu Fındık
Klebsiella pneumoniae is an opportunistic pathogen that commonly affects immunosuppressed patients and causes nosocomial infections. K.pneumoniae has a variety of virulence factors, especially capsule polysaccharide, hypermucoviscosity (HV), fimbriae, toxins and determinants for iron acquisition. The aim of this study was to detect the virulence factors in K.pneumoniae strains isolated from nosocomial infections in two years. Fifty three K.pneumoniae strains isolated from the samples of patients with nosocomial infections in the Medical Microbiology Laboratory of Selcuk University Faculty of Medicine Hospital between 2011 and 2013 were included in the study...
October 2017: Mikrobiyoloji Bülteni
https://www.readbyqxmd.com/read/29150269/potential-role-of-the-virchow-robin-space-in-the-pathogenesis-of-bacterial-meningitis
#2
Patrick Chan, Denis J Meerdink, James A Uchizono
Meningitis is an infectious disease commonly arising from a bacterial etiology. The rapid progression of morbidity and mortality due to bacterial meningitis requires critical and imminent time-dependent clinical intervention. Although it is unambiguously clear that bacteria must infiltrate the cerebrospinal fluid, the sequence of events in the pathogenesis of bacterial meningitis has not been fully elucidated. Most reviews of the pathogenesis of bacterial meningitis do not specify the anatomical location of bacteria following BBB traversal...
November 2017: Medical Hypotheses
https://www.readbyqxmd.com/read/29149390/decompressive-craniectomy-and-csf-disorders-in-children
#3
Marie Manfiotto, Carmine Mottolese, Alexandru Szathmari, Pierre-Aurelien Beuriat, Olivier Klein, Matthieu Vinchon, Edouard Gimbert, Thomas Roujeau, Didier Scavarda, Michel Zerah, Federico Di Rocco
INTRODUCTION: Decompressive craniectomy (DC) is a lifesaving procedure but is associated to several post-operative complications, namely cerebrospinal fluid (CSF) dynamics impairment. The aim of this multicentric study was to evaluate the incidence of such CSF alterations after DC and review their impact on the overall outcome. MATERIAL AND METHODS: We performed a retrospective multicentric study to analyze the CSF disorders occurring in children aged from 0 to 17 years who had undergone a DC for traumatic brain injury (TBI) in the major Departments of Pediatric Neurosurgery of France between January 2006 and August 2016...
October 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/29141865/development-and-plasticity-of-meningeal-lymphatic-vessels
#4
Salli Antila, Sinem Karaman, Harri Nurmi, Mikko Airavaara, Merja H Voutilainen, Thomas Mathivet, Dmitri Chilov, Zhilin Li, Tapani Koppinen, Jun-Hee Park, Shentong Fang, Aleksanteri Aspelund, Mart Saarma, Anne Eichmann, Jean-Léon Thomas, Kari Alitalo
The recent discovery of meningeal lymphatic vessels (LVs) has raised interest in their possible involvement in neuropathological processes, yet little is known about their development or maintenance. We show here that meningeal LVs develop postnatally, appearing first around the foramina in the basal parts of the skull and spinal canal, sprouting along the blood vessels and cranial and spinal nerves to various parts of the meninges surrounding the central nervous system (CNS). VEGF-C, expressed mainly in vascular smooth muscle cells, and VEGFR3 in lymphatic endothelial cells were essential for their development, whereas VEGF-D deletion had no effect...
November 15, 2017: Journal of Experimental Medicine
https://www.readbyqxmd.com/read/29133004/neuroendoscopic-treatment-of-cystic-craniopharyngiomas-a-case-series-with-systematic-review-of-the-literature
#5
Liverana Lauretti, Francois Yves Legninda Sop, Roberto Pallini, Eduardo Fernandez, Quintino Giorgio D'Alessandris
BACKGROUND: Total removal of craniopharyngiomas is burdened by high morbidity. In cases of a cystic or mixed craniopharyngioma, when the symptoms are caused by the cystic component of the tumor, a less invasive surgical approach aiming at cyst drainage may be recommended. Here we report our experience with intraventricular neuroendoscopy, describing our clear-cut surgical technique, and analyzing results in the context of literature data. METHODS: We reviewed the clinical data of 8 consecutive adult patients affected by cystic or mixed craniopharyngioma that were treated with intraventricular neuroendoscopy at our Institution in the last decade...
November 10, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29123886/sudden-cerebral-depression-detected-by-bispectral-index-monitoring-in-cryptococcal-meningitis-with-elevated-near-fatal-cerebrospinal-fluid-pressure
#6
Hironori Matsumoto, Suguru Annen, Kensuke Umakoshi, Jun Takeba, Satoshi Kikuchi, Yuki Nakabayashi, Naoki Moriyama, Muneaki Ohshita, Mayuki Aibiki
Case: An increase in cerebrospinal fluid pressure (CSFP) is usually prominent in cryptococcal meningitis, which has a high mortality rate, so aggressive management to control CSFP is crucial. In this case, a 40-year-old-man survived cryptococcal meningitis treated with continuous spinal drainage under bispectral index (BIS) monitoring. He unexpectedly showed hypertension, went into a coma, and even loss his light reflexes due to CSFP elevation. His BIS values had abruptly dropped before developing these symptoms, but dramatically recovered after lumbar puncture drainage, suggesting that BIS monitoring could reflect cerebral function changes due to CSFP alternations...
July 2017: Acute Medicine & Surgery
https://www.readbyqxmd.com/read/29115000/cerebrospinal-fluid-serum-glucose-ratio-in-the-ventricular-and-lumbar-compartment-implications-for-clinical-practice
#7
Harald Hegen, Janette Walde, Michael Auer, Florian Deisenhammer
BACKGROUND: Calculation of the cerebrospinal fluid/ serum glucose (CSF/SGlu ) ratio is part of the routine CSF work-up. Reference values have been defined for lumbar CSF, however, are lacking for ventricular CSF. The objective of this study was to investigate whether CSF/SGlu ratio is comparable between lumbar and ventricular compartment, and to determine cut-off values for CSF/SGlu ratio in ventricular CSF. METHODS: We included CSF samples, which were collected either by lumbar puncture or ventricular drainage, showed red blood cell (RBC) count <500/μl, normal white blood cell (WBC) count and age-related normal total protein content, had simultaneously withdrawn serum sample and time to laboratory processing of ≤2 hours, resulting in 1808 sample pairs...
November 8, 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/29114279/comparison-between-ventriculosubgaleal-shunt-and-extraventricular-drainage-to-treat-acute-hydrocephalus-in-adults
#8
Low Siaw Nee, Rahmat Harun, Pulivendhan Sellamuthu, Zamzuri Idris
Context: Hydrocephalus, due to subarachnoid or intraventricular hemorrhage (IVH), meningitis, or tumor compression, is usually transient and may resolve after treatment. There are several temporary methods of cerebrospinal fluid (CSF) diversion, none of it is superior to the other, and the decision is based on its various etiologies and factors. Ventriculosubgaleal shunt (VSGS) is one of those temporary measures, which is a simple and rapid CSF decompression method without causing electrolyte and nutritional losses...
October 2017: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/29112767/fast-and-reliable-diagnosis-of-xdr-acinetobacter-baumannii-meningitis-by-matrix-assisted-laser-desorption-ionization-time-of-flight-mass-spectrometry
#9
Grazia Brunetti, Giancarlo Ceccarelli, Alessandra Giordano, Anna Sara Navazio, Pietro Vittozzi, Mario Venditti, Giammarco Raponi
Bacterial meningitis is a medical emergency needing quick and timely diagnosis. Even though meningitis caused by Acinetobacter baumannii is relatively rare, it is associated with high mortality rates especially in neurosurgery patients and represents a serious therapeutic problem due to the limited penetration of effective antibiotics into the cerebrospinal fluid. Recently, matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF) has been effectively used as a rapid method for microbial identification...
November 7, 2017: New Microbiologica
https://www.readbyqxmd.com/read/29110778/more-than-a-drainage-fluid-the-role-of-csf-in-signaling-in-the-brain-and-other-effects-on-brain-tissue
#10
Sebastian Illes
Current progress in neuroscience demonstrates that the brain is not an isolated organ and is influenced by the systemic environment and extracerebral processes within the body. In view of this new concept, blood and cerebrospinal fluid (CSF) are important body fluids linking extracerebral and intracerebral processes. For decades, substantial evidence has been accumulated indicating that CSF modulates brain states and influences behavior as well as cognition. This chapter provides an overview of how CSF directly modulates the function of different types of brain cells, such as neurons, neural stem cells, and CSF-contacting cells...
2017: Handbook of Clinical Neurology
https://www.readbyqxmd.com/read/29058970/cerebrospinal-fluid-drainage-and-thoracic-endovascular-aneurysm-repair
#11
Gilles Godet, Michèle Bertrand, Marie-Hélène Fléron, Jean-Pierre Goarin, Pascal Colson, Alain Cardon, Fabien Koskas, Jean-Philippe Verhoye, Edouard Kieffer
Spinal cord complications including paraplegia and partial neurologic deficits remain a frequent problem during repair of descending thoracic or thoracoabdominal aortic aneurysms. Effective prevention of this dreaded complication is of paramount importance. Among the many adjuncts that have been proposed to prevent spinal cord complications, spinal fluid drainage is one that has been used by numerous teams. The aim of this review is to answer the following question: does spinal fluid drainage afford spinal cord protection during both open and endovascular repair of thoracic or thoracoabdominal aortic aneurysms?...
January 1, 2017: Asian Cardiovascular & Thoracic Annals
https://www.readbyqxmd.com/read/29027589/diagnosis-and-treatment-of-severe-neurosurgical-patients-with-pyogenic-ventriculitis-caused-by-gram-negative-bacteria
#12
Feng Shang, Yueqiao Xu, Ning Wang, Weitao Cheng, Wenjin Chen, Wanru Duan
The aim of the study is to explore the experiences in diagnosis and treatment of severe neurosurgical patients with pyogenic ventriculitis caused by gram-negative bacteria (G(-)). Nineteen patients with pyogenic ventriculitis were reviewed for their treatment. The bacterial testing results of cerebrospinal fluid (CSF), the clinical intervention, and the patients' prognosis were evaluated. The bacterial smears of ventricular drainage from all the cases were G(-) bacteria. Head CT and MRI scans confirmed that they were intraventricular empyema...
October 13, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/29026666/bedside-twist-drill-aspiration-of-cerebral-abscess-less-than-2-5-cm-in-size-a-case-series-and-discussion
#13
Tyler Carson, Dan Miulli
BACKGROUND: Intracranial abscess remains a potentially deadly condition despite development of newer antibiotics and improved surgical methods. Many studies have evaluated the surgical indications for abscess drainage, and it has been generally accepted that intracranial abscesses greater than 2.5 cm may best be treated with surgical intervention followed by antibiotic therapy. More recently, studies have shown good results with stereotactic aspiration of abscesses to 1 cm in size. Furthermore, a recent case series in 2014 of 103 cases of bedside twist drill aspiration of cerebral abscess >2...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/29019146/spinal-cord-injury-after-thoracic-endovascular-aortic-aneurysm-repair
#14
Hamdy Awad, Mohamed Ehab Ramadan, Hosam F El Sayed, Daniel A Tolpin, Esmerina Tili, Charles D Collard
PURPOSE: Thoracic endovascular aortic aneurysm repair (TEVAR) has become a mainstay of therapy for aneurysms and other disorders of the thoracic aorta. The purpose of this narrative review article is to summarize the current literature on the risk factors for and pathophysiology of spinal cord injury (SCI) following TEVAR, and to discuss various intraoperative monitoring and treatment strategies. SOURCE: The articles considered in this review were identified through PubMed using the following search terms: thoracic aortic aneurysm, TEVAR, paralysis+TEVAR, risk factors+TEVAR, spinal cord ischemia+TEVAR, neuromonitoring+thoracic aortic aneurysm, spinal drain, cerebrospinal fluid drainage, treatment of spinal cord ischemia...
December 2017: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
https://www.readbyqxmd.com/read/29017806/implementation-of-a-bundled-protocol-significantly-reduces-risk-of-spinal-cord-ischemia-after-branched-or-fenestrated-endovascular-aortic-repair
#15
Salvatore T Scali, Moses Kim, Paul Kubilis, Robert J Feezor, Kristina A Giles, Brittney Miller, Javairiah Fatima, Thomas S Huber, Scott A Berceli, Martin Back, Adam W Beck
OBJECTIVE: Spinal cord ischemia (SCI) is a devastating complication after branched or fenestrated endovascular aortic repair (B/FEVAR) for thoracoabdominal aortic disease. The purpose of this analysis was to describe the impact of a bundled clinical care protocol designed to reduce the risk of SCI in this population of patients. METHODS: A bundled SCI prevention protocol including cerebrospinal fluid drainage, blood pressure parameters, transfusion goals, and pharmacologic adjuncts (steroids, naloxone) was initiated in May 2015...
October 7, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28989043/cerebrospinal-fluid-leak-at-percutaneous-exit-of-ventricular-catheter-as-crucial-risk-factor-for-external-ventricular-drainage-related-infection-in-adult-neurosurgical-patients
#16
Jaechan Park, Yeon-Ju Choi, Boram Ohk, Hyun-Ha Chang
OBJECTIVE: The placement of a ventricular catheter for temporary cerebrospinal fluid (CSF) diversion is associated with a considerable risk of CSF infection. The authors investigated the effect of a CSF leak on CSF-related infection and the predisposing factors for a CSF leak. METHODS: Fifty-two patients who underwent external ventricular drainage (EVD) for acute hydrocephalus associated with a subarachnoid hemorrhage (SAH) or intraventricular hemorrhage (IVH) were enrolled in this prospective study...
October 5, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28973347/a-report-of-2-cases-of-brainstem-hemorrhage-after-suboccipital-craniectomy-for-chiari-decompression
#17
Sean P Polster, Mark C Dougherty, Hussein A Zeineddine, Seon-Kyu Lee, David Frim
BACKGROUND AND IMPORTANCE: Decompression surgery for Chiari malformation is known to have very low procedure-related complications. There has been no report of post-Chiari malformation decompression surgery development of brainstem hemorrhage. We report 2 post-Chiari decompression surgery brainstem hemorrhage cases with 2-yr follow-up. CLINICAL PRESENTATION: Two cases were reviewed in which patients underwent uncomplicated suboccipital craniectomy with expansive autologous pericranium duraplasty for Chiari decompression...
July 11, 2017: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/28969203/remote-cerebellar-haemorrhage-occurring-after-transcranial-pituitary-surgery
#18
Numan Karaarslan, Mehmet Sabri Gürbüz, Tezcan Caliskan, Tamer Tunckale
Post supratentorial and spinal surgeries, in rare cases, Remote Cerebellar Haemorrhage (RCH) develops as a complication. Although the exact aetiology of RCH remains uncertain, excessive drainage of the Cerebrospinal Fluid (CSF) is accepted as the most possible cause. It has been suggested that overdrainage of CSF leads to stretching and resultantly tearing of the cerebellar veins. Early diagnosis and appropriate management decrease mortality and morbidity significantly. In this report, we present a case of RCH encountered on the third postoperative day of transcranial pituitary surgery and discuss the possible causative factors...
August 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28967591/syringomyelia-due-to-lumbar-spinal-fluid-drainage-in-the-acute-phase-of-subarachnoid-hemorrhage-a-case-report
#19
Akira Machida, Mutsumi Fujii, Tasuku Ishihara, Eiichiro Amano, Shinichi Otsu, Shoko Fujii, Natsumi Tamada, Juri Kiyokawa, Masataka Yoshimura, Shin Hirota, Shinji Yamamoto
Lumbar spinal fluid drainage is a common procedure for treating hydrocephalus and alleviating vasospasm by egesting blood in the subarachnoid cavity after subarachnoid hemorrhage. Despite being an effective and safe procedure, cerebrospinal fluid overdrainage might result in serious complications. Here we report the case of a 49-year-old man who suffered from tonsillar herniation with subsequent cervicothoracic syringomyelia in the acute phase of subarachnoid hemorrhage due to vertebral artery dissection. About 2 weeks after lumbar drainage was switched from external ventricular drainage initiated on the day of subarachnoid hemorrhage, the recovery from the disturbance of consciousness revealed tetraplegia, and magnetic resonance imaging demonstrated tonsillar herniation and syringomyelia...
September 26, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28960686/quantifying-response-to-intracranial-pressure-normalization-in-idiopathic-intracranial-hypertension-via-dynamic-neuroimaging
#20
Svetlana Lublinsky, Anat Kesler, Alon Friedman, Anat Horev, Ilan Shelef
BACKGROUND: Idiopathic intracranial hypertension (IIH) is characterized by elevated intracranial pressure without a clear cause. PURPOSE: To investigate dynamic imaging findings in IIH and their relation to mechanisms underlying intracranial pressure normalization. STUDY TYPE: Prospective. POPULATION: Eighteen IIH patients and 30 healthy controls. FIELD STRENGTH/SEQUENCE: T1 -weighted, venography, fluid attenuation inversion recovery, and apparent diffusion coefficients were acquired on 1...
September 27, 2017: Journal of Magnetic Resonance Imaging: JMRI
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