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ct volumetry of pancreas

Steven W Warmann, Andrea Schenk, Juergen F Schaefer, Martin Ebinger, Gunnar Blumenstock, Ilias Tsiflikas, Joerg Fuchs
BACKGROUND: In complex malignant pediatric liver tumors there is an ongoing discussion regarding surgical strategy; for example, primary organ transplantation versus extended resection in hepatoblastoma involving 3 or 4 sectors of the liver. We evaluated the possible role of computer-assisted surgery planning in children with complex hepatic tumors. METHODS: Between May 2004 and March 2016, 24 Children with complex liver tumors underwent standard multislice helical CT scan or MRI scan at our institution...
June 1, 2016: Journal of Pediatric Surgery
Veit Phillip, Tina Zahel, Klaus Bärtl, Sebastian Rasch, Oliver Ebert, Roland M Schmid, Ernst Rummeny, Hana Algül
BACKGROUND/OBJECTIVES: Angiogenesis plays a central role in tumor growth and metastasis and tyrosine kinases are crucial in the modulation of growth factor signaling. Several side effects of tyrosine kinase inhibitors have been reported, including diarrhea due to pancreatic insufficiency. The suspected mechanism is the anti-angiogenetic effect of the inhibited vascular endothelial growth factor (VEGF) causing a disturbance of the microvasculation. The aim of the present study was to determine the volume of the pancreas before and after a therapy both with the multi-tyrosine kinase inhibitor Sorafenib and Bevacizumab, which is a humanized monoclonal immunoglobulin G1 antibody against VEGF...
July 2016: Pancreatology: Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
Jae Hyun Kwon, Song Cheol Kim, In Kyong Shim, Ki Byung Song, Jae Hoon Lee, Dae Wook Hwang, Kwang-Min Park, Young-Joo Lee
OBJECTIVES: Glucose homeostasis changes after pancreatic resection are not well understood. We aimed to identify the incidence of, and risk factors for, a change in glucose homeostasis in patients who underwent pancreatectomy for benign pancreatic tumors. METHODS: Clinical and pathological data from 229 patients were collected prospectively and analyzed retrospectively. The pancreas resection volume was calculated by computed tomography volumetry. RESULTS: After pancreatectomy, newly diagnosed diabetes mellitus (DM) occurred in 52 patients (22...
November 2015: Pancreas
Veit Phillip, Tina Zahel, Assiye Danninger, Mert Erkan, Martin Dobritz, Jörg M Steiner, Jörg Kleeff, Roland M Schmid, Hana Algül
BACKGROUND/OBJECTIVES: Regeneration of the pancreas has been well characterized in animal models. However, there are conflicting data on the regenerative capacity of the human pancreas. The aim of the present study was to assess the regenerative capacity of the human pancreas. METHODS: In a retrospective study, data from patients undergoing left partial pancreatic resection at a single center were eligible for inclusion (n = 185). Volumetry was performed based on 5 mm CT-scans acquired through a 256-slice CT-scanner using a semi-automated software...
September 2015: Pancreatology: Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
Jihee Hwang, Dae Yeon Kim, Seong Chul Kim, Jung-Man Namgoong, Seung-Mo Hong
PURPOSE: We aimed to review clinical and histologic findings of solid-pseudopapillary neoplasm (SPN) in children and determine the predictive factor of the malignancy. METHOD: The records of 45 patients (9 males, 36 females) who underwent surgery for SPN in the Asan Medical Center from 1992 to 2012 were retrospectively analyzed. We analyzed the factors between histologic benign group (n=36) and malignant group (n=9). RESULTS: The mean age of children was 14...
December 2014: Journal of Pediatric Surgery
Rie Sato, Masashi Kishiwada, Naohisa Kuriyama, Yoshinori Azumi, Shugo Mizuno, Masanobu Usui, Hiroyuki Sakurai, Masami Tabata, Tomomi Yamada, Shuji Isaji
BACKGROUND: The aim of the present study was to evaluate perioperative risk factors for development of nonalcoholic fatty liver disease (NAFLD) after pancreaticoduodenectomy (PD), paying special attention to remnant pancreatic volume (RPV) and postoperative infection. METHODS: We reviewed the charts of 110 patients who had been followed more than 6 months after PD. These patients were classified into the two groups according to RPV measured by CT volumetry at one month: large-volume group (LVG) (10 ml or more, n = 75) and small-volume group (SVG) (less than 10 ml, n = 35)...
August 2014: Journal of Hepato-biliary-pancreatic Sciences
I Matsumoto, M Shinzeki, S Asari, T Goto, S Shirakawa, T Ajiki, T Fukumoto, Y Ku
BACKGROUND: Living donor pancreas transplantation (LDPT) reduces the number of deaths of diabetic patients on dialysis and of candidates on the waiting lists and helps to overcome the organ shortage. Stringent criteria must be applied to minimize the risk of metabolic complications for living donors. The Japanese Pancreas and Islet Transplantation Association (JPITA) proposed LDPT guidelines in 2010. In this study, we retrospectively evaluated glucose metabolism of the patients who underwent distal pancreatectomy (DP) according to the donor criteria of the LDPT guidelines proposed by the JPITA...
April 2014: Transplantation Proceedings
Sachiyo Shirakawa, Ippei Matsumoto, Hirochika Toyama, Makoto Shinzeki, Tetsuo Ajiki, Takumi Fukumoto, Yonson Ku
INTRODUCTION: Pancreatogenic diabetes after pancreatectomy is of growing importance due to the increasing life expectancy of pancreatectomized patients. Although reduction of pancreatic volume is thought to affect glucose metabolism, a consistent relationship has yet to be determined. This study aimed to investigate functional consequences of distal pancreatectomy (DP) in preoperatively non-diabetic patients. METHODS: This study included 61 non-diabetic patients who underwent DP...
December 2012: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
Eva Lundqvist, Monica Segelsjö, Anna Andersson, Anders Magnusson, Ali-Reza Biglarnia
BACKGROUND: Unlike other solid organ transplants, pancreas allografts can undergo a substantial decrease in baseline volume after transplantation. This phenomenon has not been well characterized, as there are insufficient data on reliable and reproducible volume assessments. We hypothesized that characterization of pancreatic volume by means of computed tomography (CT) could be a useful method for clinical follow-up in pancreas transplant patients. PURPOSE: To evaluate the feasibility and reliability of pancreatic volume assessment using CT scan in transplanted patients...
November 1, 2012: Acta Radiologica
Dong-Do You, Seong-Ho Choi, Dong-Wook Choi, Jin-Seok Heo, Cheon-Yu Ho, Woo-Seok Kim
BACKGROUND:   To analyse the association between pancreatogenic diabetes and the volume of the remnant pancreas after pancreaticoduodenectomy and to identify clinicopathologic factors correlated with pancreatogenic diabetes. METHODS:   Among the patients who underwent pancreaticoduodenenctomy from 2003 to 2004, 55 patients who survived by 2009 and were able to measure the volume of the pancreas pre- and post-operatively by CT volumetry were included in this study...
June 2012: ANZ Journal of Surgery
A Djuric-Stefanovic, D Masulovic, J Kostic, K Randjic, D Saranovic
PURPOSE: The purpose of this study was to estimate the volume of normal pancreas in adults using the CT volumetry (summation of the areas technique), analyze the correlation between the volume and the diameters of pancreas, which are measurable by the cross-sectional imaging, and assess the relationship with the gender, age, and body constitution. METHODS: 220 CT examinations were analyzed retrospectively (102 females, 118 males; age 16-82, average 56). Following diameters were measured: cranial-caudal-CC(pancreas), CC(body&tail), CC(body), CC(head); anterior-posterior--AP(tail), AP(body), AP(head); lengths--LL(head), L(body&tail); and maximal transversal diameter of the L1 vertebral body (LL(L1)) and thickness of the abdominal subcutaneous fat (AP(ASF)), as markers of body constitution...
November 2012: Surgical and Radiologic Anatomy: SRA
Naoaki Sakata, Shinichi Egawa, Toshiki Rikiyama, Gumpei Yoshimatsu, Kunihiro Masuda, Hideo Ohtsuka, Shigeru Ottomo, Kei Nakagawa, Hiroki Hayashi, Takanori Morikawa, Tohru Onogawa, Kuniharu Yamamoto, Hiroshi Yoshida, Masanori Akada, Fuyuhiko Motoi, Takeshi Naitoh, Yu Katayose, Michiaki Unno
UNLABELLED: BACKGROUNS/AIMS: There are few studies about the assessment of pancreatic function using computed tomography (CT) volumetry. In this study, we examined the correlation between CT volumetry and endocrine parameters (blood glucose and HbA1c) of the pancreas. METHODS: A total of 68 patients underwent enhanced CT for pancreatic disease from January to December in 2008. In particular, we analyzed the correlation of diabetic status and pancreatic CT parameters at 1 year after pancreatoduodenectomy in 32 patients...
March 2011: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
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