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Panniculitis dermatomyositis

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https://www.readbyqxmd.com/read/27516827/-dermatomyositis-and-panniculitis-the-function-of-immunoglobulins
#1
Nadia Ben Abdelhafidh, Sana Toujeni, Asma Kefi, Najeh Bousetta, Sameh Sayhi, Imen Gharsallah, Salah Othmani
Panniculitis is an inflammatory disease of subcutaneous adipose tissue which is rarely associated with dermatomyositis. It can occur before, after or simultaneously with muscle damage. In most cases, the evolution of panniculitis and of other dermatomyositis affections is favorable with corticosteroids and/or immunosuppressants. We report the case of a 48 year-old patient who developed panniculitis lesions 2 months before having muscular signs. Skin involvement was resistant to corticosteroid treatment associated with immunosuppressants drugs...
2016: Pan African Medical Journal
https://www.readbyqxmd.com/read/27279974/-panniculitis-in-patient-undergoing-treatment-for-dermatomyositis-with-methotrexate
#2
Nabil Bel Feki, Monia Smiti Khanfir, Imed Ben Ghorbel, Fatma Said, Mohamed Habib Houman
Panniculitis is a rare cutaneous manifestation of dermatomyositis (DM). The appearance of panniculitis during treatment with methotrexate (MTX) is exceptional and has only been described in 3 cases. We report a case of a 50-year-old woman suffering from DM since 1997 who was treated with corticosteroids showing favorable clinical and biological evolution. When a relapse occurred 2 years later, she was treated with higher-dose of corticosteroids in combination with a 7,5 mg weekly dose of methotrexate. The evolution was rapidly favorable...
2016: Pan African Medical Journal
https://www.readbyqxmd.com/read/26988082/imaging-of-connective-tissue-diseases-of-the-head-and-neck
#3
Ahmed Abdel Khalek Abdel Razek
We review the imaging appearance of connective tissue diseases of the head and neck. Bilateral sialadenitis and dacryoadenitis are seen in Sjögren's syndrome; ankylosis of the temporo-mandibular joint with sclerosis of the crico-arytenoid joint are reported in rheumatoid arthritis and lupus panniculitis with atypical infection are reported in patients with systemic lupus erythematosus. Relapsing polychondritis shows subglottic stenosis, prominent ear and saddle nose; progressive systemic sclerosis shows osteolysis of the mandible, fibrosis of the masseter muscle with calcinosis of the subcutaneous tissue and dermatomyositis/polymyositis shows condylar erosions and autoimmune thyroiditis...
June 2016: Neuroradiology Journal
https://www.readbyqxmd.com/read/26971888/panniculitis-in-juvenile-dermatomyositis-report-of-a-case-and-review-of-the-published-work
#4
Andac Salman, Ozgur Kasapcopur, Tulin Ergun, Ayse Nigar Durmus Ucar, Cuyan Demirkesen
We report a 15-year-old girl who presented with indurated, subcutaneous nodules in addition to classical findings of juvenile dermatomyositis. Histopathological examination confirmed the diagnosis of panniculitis associated with juvenile dermatomyositis. Considering that panniculitis is a rare cutaneous manifestation of juvenile dermatomyositis, we present a patient with a brief review of the published work to highlight the importance of keeping juvenile dermatomyositis in mind among the etiologies of pediatric panniculitis...
August 2016: Journal of Dermatology
https://www.readbyqxmd.com/read/26100618/cutaneous-manifestations-in-dermatomyositis-key-clinical-and-serological-features-a-comprehensive-review
#5
Yoshinao Muro, Kazumitsu Sugiura, Masashi Akiyama
Dermatomyositis (DM) is a common idiopathic inflammatory myopathy. The pathogenesis is considered to be microangiopathy affecting skin and muscle. The cutaneous manifestations of DM are the most important aspect of this disease, and their correct evaluation is important for early diagnosis. The skin signs are various: Some are pathognomonic or highly characteristic, and others are compatible with DM. Recently, DM has been categorized into several disease subsets based on the various autoantibodies present in patients...
June 23, 2015: Clinical Reviews in Allergy & Immunology
https://www.readbyqxmd.com/read/25977892/calcific-panniculitis-and-nasopharyngeal-cancer-associated-adult-onset-dermatomyositis-a-case-report-and-literature-review
#6
Manasmon Chairatchaneeboon, Kanokvalai Kulthanan, Araya Manapajon
Panniculitis is an uncommon cutaneous manifestation in dermatomyositis. It not only occurs in idiopathic dermatomyositis, but also rarely occurs in the setting of malignancy-associated dermatomyositis. Calcinosis cutis is also less likely to be found in adult-onset dermatomyositis. In malignancy-associated dermatomyositis, panniculitis can precede, concur, or follow the diagnosis of malignancy. We report the case of a 26-year-old Thai female with calcific panniculitis in the setting of adult-onset dermatomyositis associated with nasopharyngeal cancer...
2015: SpringerPlus
https://www.readbyqxmd.com/read/25243267/anti-mda5-positive-clinically-amyopathic-dermatomyositis-presenting-with-severe-cardiomyopathy
#7
I Pau-Charles, P J Moreno, K Ortiz-Ibáñez, M C Lucero, A Garcia-Herrera, G Espinosa, J M Nicolás, P Castro, J M Grau, L Casciola-Rosen, J M Mascaró
BACKGROUND: Anti-MDA5 (Melanoma differentiation-associated gene 5) positive dermatomyositis is a new variant of clinically amyopathic dermatomyositis that presents with characteristic mucocutaneous findings and is associated with a higher risk of developing rapidly progressive interstitial lung disease. Because its presentation differs from that of classical dermatomyositis, this entity can be a diagnostic challenge for the clinician. METHODS & RESULTS: We present the case of a 55-year-old male with a 7-month history of chill sensation, constitutional symptoms and polyarthralgia...
August 2014: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/24990342/a-subcutaneous-panniculitis-like-t-cell-lymphoma-mimicking-dermatomyositis
#8
Shinjiro Kaieda, Akiko Idemoto, Naomi Yoshida, Hiroaki Ida
No abstract text is available yet for this article.
2014: Internal Medicine
https://www.readbyqxmd.com/read/24741583/anti-mda5-antibodies-in-a-large-mediterranean-population-of-adults-with-dermatomyositis
#9
Moises Labrador-Horrillo, Maria Angeles Martinez, Albert Selva-O'Callaghan, Ernesto Trallero-Araguas, Eva Balada, Miquel Vilardell-Tarres, Cándido Juárez
A new myositis-specific autoantibody directed against melanoma differentiation-associated gene 5 (anti-MDA5) has been described in patients with dermatomyositis (DM). We report the clinical characteristics of patients with anti-MDA5 in a large Mediterranean cohort of DM patients from a single center, and analyze the feasibility of detecting this autoantibody in patient sera using new assays with commercially available recombinant MDA5. The study included 117 white adult patients with DM, 15 (13%) of them classified as clinically amyopathic dermatomyositis (CADM)...
2014: Journal of Immunology Research
https://www.readbyqxmd.com/read/24689899/dermatomyositis-panniculitis-a-case-report
#10
Melissa Carroll, Nick Mellick, Godfrey Wagner
Dermatomyositis-related panniculitis is a rare cutaneous manifestation of dermatomyositis. There are few reported cases in the medical literature. We present the case of a 60-year-old woman with a 2-year history of dermatomyositis and recent biopsy-confirmed panniculitis treated with prednisone, cyclophosphamide and i.v. immunoglobulin.
August 2015: Australasian Journal of Dermatology
https://www.readbyqxmd.com/read/24609759/tuberculous-pyomyositis-a-re-emerging-entity-of-many-faces
#11
REVIEW
Theodora Simopoulou, Areti Varna, Zoe Dailiana, Christina Katsiari, Ioannis Alexiou, Georgios Basdekis, Konstantinos N Malizos, Lazaros I Sakkas
Tuberculosis (TB) has become a global concern due to its increasing incidence, particularly in immunocompromised patients, closely following the migratory patterns of populations. TB pyomyositis is a rare extrapulmonary manifestation of TB. Its clinical presentation varies and requires a high degree of suspicion for early diagnosis. We present three patients diagnosed with TB pyomyositis: a 46-year-old man with dermatomyositis (DM) and hepatitis B who presented with fever, muscle weakness, and an abscess at the right proximal arm; a 71-year-old immunocompetent male, with a past medical history of tuberculous lymphadenopathy in childhood, who presented with a 2-month history of fever and pain at the right thigh, and a 44-year-old woman with systemic lupus erythematosus (SLE) on prednisone and methotrexate who presented with skin eruption at her thighs mimicking lupus panniculitis...
April 2016: Clinical Rheumatology
https://www.readbyqxmd.com/read/24329416/plain-radiography-is-effective-for-the-detection-of-calcinosis-cutis-occurring-in-association-with-autoimmune-connective-tissue-disease
#12
V Shahi, D A Wetter, B M Howe, M D Ringler, M D P Davis
BACKGROUND: Studies on the radiological findings of calcinosis cutis in patients with autoimmune connective tissue disease (ACTD) are limited. OBJECTIVES: To describe imaging findings and radiological patterns of calcinosis cutis occurring with ACTD. METHODS: We retrospectively reviewed the cases of 37 patients with imaging studies assessing for calcinosis cutis associated with ACTD at our institution between 1996 and 2009. A formal blinded review of available images (i...
May 2014: British Journal of Dermatology
https://www.readbyqxmd.com/read/24007962/-paraneoplastic-rheumatic-syndromes
#13
Abraham Edgar Gracia-Ramos, Olga Lidia Vera-Lastra
Paraneoplastic rheumatic syndromes are defined as those events associated with cancer that occur away from the primary tumor or its metastases and are induced by the presence of the tumor through biological products like hormones, peptides, autocrine or paracrine mediators, antibodies or cytotoxic lymphocytes. Of these, hypertrophic osteoarthropathy, carcinomatous polyarthritis, dermatomyositis/polymyositis, and paraneoplastic vasculitis are the most frequently recognized. Other less known associations are based upon a smaller number of case reports, and include palmar fasciitis, panniculitis, erythema nodosum, Raynaud¥s phenomenon, erythromelalgia and Lupus-like syndrome...
April 2012: Revista Alergia Mexico: Organo Oficial de la Sociedad Mexicana de Alergia e Inmunología, A.C
https://www.readbyqxmd.com/read/23588884/the-presenting-manifestations-of-subcutaneous-panniculitis-like-t-cell-lymphoma-and-t-cell-lymphoma-and-cutaneous-%C3%AE-%C3%AE-t-cell-lymphoma-may-mimic-those-of-rheumatic-diseases-a-report-of-11-cases
#14
Lin Yi, Shi Qun, Zheng Wenjie, Zhang Wen, Li Jian, Zhao Yan, Zhang Fengchun
This study aims to investigate the association between subcutaneous panniculitis-like T-cell lymphoma (SPTCL) or cutaneous gamma/delta T-cell lymphoma (CGDTCL) and a variety of manifestations that mimic autoimmune disorders. A retrospective chart review was made for 11 patients who were initially diagnosed as autoimmune diseases but finally turned out to be SPTCL or CGDTCL. Eleven patients were initially diagnosed with erythema nodosum, nodular panniculitis, lupus erythematosus profundus, systemic vasculitis, dermatomyositis, or pyoderma gangrenosum...
August 2013: Clinical Rheumatology
https://www.readbyqxmd.com/read/23496323/cutaneous-ulceration-more-than-skin-deep
#15
R Lamb, S Digby, W Stewart, A Drummond
No abstract text is available yet for this article.
June 2013: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/22741936/update-on-management-of-connective-tissue-panniculitides
#16
Inbal Braunstein, Victoria P Werth
In connective tissue diseases, panniculitis can be the sole manifestation or can occur along with the underlying disease process. The best described forms of connective tissue panniculitis are lupus erythematosus panniculitis and lupus profundus, panniculitis associated with dermatomyositis, and morphea- and scleroderma-associated panniculitis. These processes cause significant morbidity, such as deep atrophic scars, cosmetic disfigurement, and psychiatric sequelae. Because the inflammation is located in the subcutaneous adipose layer, topical therapies may not penetrate enough to be effective, and systemic agents are required...
March 2012: Dermatologic Therapy
https://www.readbyqxmd.com/read/22431715/panniculitis-associated-with-dermatomyositis-and-recurrent-ovarian-cancer
#17
Sasha D Girouard, Nicole F Velez, Richard T Penson, Elena M Massarotti, Ruth Ann Vleugels
BACKGROUND: Panniculitis is a rare cutaneous manifestation of dermatomyositis (DM), typically presenting as tender, erythematous subcutaneous nodules. Complications, such as pain, calcinosis, and lipoatrophy, are associated with high morbidity. While it has been suggested that panniculitis in DM may correlate with a better prognosis, our understanding of its true significance, prognostic implications, and management is limited by the paucity of reported cases. We describe the first reported case to our knowledge of DM-associated panniculitis in the setting of ovarian adenocarcinoma as well as in association with a recurrent malignancy...
June 2012: Archives of Dermatology
https://www.readbyqxmd.com/read/22184719/calcinosis-cutis-occurring-in-association-with-autoimmune-connective-tissue-disease-the-mayo-clinic-experience-with-78-patients-1996-2009
#18
Samuel J Balin, David A Wetter, Louise K Andersen, Mark D P Davis
OBJECTIVE: To describe characteristics and treatment of patients with calcinosis cutis in the clinical setting of autoimmune connective tissue disease (ACTD). DESIGN: Retrospective study. SETTING: Tertiary referral center. PATIENTS: Seventy-eight patients with calcinosis cutis and ACTD between 1996 and 2009. MAIN OUTCOME MEASURES: Clinical features, treatments, and outcomes of patients with calcinosis cutis in the clinical setting of ACTD...
April 2012: Archives of Dermatology
https://www.readbyqxmd.com/read/21437539/panniculitis-in-a-patient-with-dermatomyositis
#19
Mariana Arias, María Inés Hernández, Lais Gomes Barbosa Cunha, María Cristina Kien, Alejandra Abeldaño
Panniculitis is a rarely reported clinical finding in dermatomyositis. It may precede the other manifestations associated with dermatomyositis by as much as 14 months. In all cases, myositis and panniculitis improve simultaneously during treatment. The present report describes the case of a 30-year-old female patient with clinical and histopathological findings consistent with panniculitis two months after the onset of the muscle and cutaneous symptoms that permitted diagnosis of dermatomyositis. The skin lesions regressed following steroid treatment...
January 2011: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/21152807/cutaneous-manifestations-of-internal-malignancies-in-a-tertiary-health-care-hospital-of-a-developing-country
#20
Alex G Ortega-Loayza, Willy Ramos, Ericson L Gutierrez, Patricia Chavez de Paz, Lucia Bobbio, Carlos Galarza
In a public hospital in Lima, Peru, 24 patients with 16 types of paraneoplastic dermatoses were identified by data collection. The most frequent dermatosis was dermatomyositis (four patients). The other dermatoses were malignant acanthosis nigricans, palmoplantar keratoderma, bullous dermatoses, lymphomatoid papulosis, edematous scarring vasculitic panniculitis, Norwegian scabies, primary systemic amyloidosis, necrolytic migratory erythema, infective dermatitis, pancreatic panniculitis, generalized pruritus, Lesser-Trelat syndrome, and acquired ichthyosis...
September 2010: Anais Brasileiros de Dermatologia
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