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https://www.readbyqxmd.com/read/28816770/prevalence-of-disability-in-patients-with-musculoskeletal-pain-and-rheumatic-diseases-in-a-population-from-cuenca-ecuador
#1
Sergio Vicente Guevara-Pacheco, Astrid Feican-Alvarado, Jorge Delgado-Pauta, Angelita Lliguisaca-Segarra, Ingris Pelaez-Ballestas
OBJECTIVE: The aim of this study was to determine the prevalence of disability in patients with musculoskeletal pain and rheumatic diseases in Cuenca, Ecuador. METHODS: We performed a cross-sectional analytical study with randomized sampling in 4877 subjects, from urban and rural areas. COPCORD (Community Oriented Program for Control of Rheumatic Diseases)-validated questionnaire was administered house-to-house to identify subjects with nontraumatic musculoskeletal pain and rheumatic diseases...
September 2017: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/28801081/effects-of-therapeutic-touch-on-healing-of-the-skin-in-rats
#2
André Luiz Thomaz de Souza, David Patrick Carvalho Rosa, Bruno Anjos Blanco, Patrícia Passaglia, Angelita Maria Stabile
CONTEXT: Therapeutic touch is a complementary treatment directed toward the balance of the energy field surrounding living beings. OBJECTIVE: This study's aim was to investigate the effect of therapeutic touch on wound area contraction and fibroblast proliferation in rat skin. DESIGN: This study was conducted using 24 male Wistar rats with dorsal wounds of diameter 8mm. The rats were divided into the following two groups: a control group: in this, the wounds were sanitized with filtered water and neutral-pH soap and a treatment group: in this, the wounds were sanitized as in the control group but the rats also underwent to daily sessions of therapeutic touch...
July 1, 2017: Explore: the Journal of Science and Healing
https://www.readbyqxmd.com/read/28791283/increasing-incidence-of-colorectal-cancer-in-adolescents-and-young-adults-aged-15-39-years-in-western-australia-1982-2007-examination-of-colonoscopy-history
#3
Lakkhina Troeung, Nita Sodhi-Berry, Angelita Martini, Eva Malacova, Hooi Ee, Peter O'Leary, Iris Lansdorp-Vogelaar, David B Preen
AIMS: To examine trends in colorectal cancer (CRC) incidence and colonoscopy history in adolescents and young adults (AYAs) aged 15-39 years in Western Australia (WA) from 1982 to 2007. DESIGN: Descriptive cohort study using population-based linked hospital and cancer registry data. METHOD: Five-year age-standardized and age-specific incidence rates of CRC were calculated for all AYAs and by sex. Temporal trends in CRC incidence were investigated using Joinpoint regression analysis...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/28754333/effect-of-allopurinol-and-uric-acid-normalization-on-serum-lipids-hyperuricemic-subjects-a-systematic-review-with-meta-analysis
#4
REVIEW
Verônica Moreira Ferreira de Castro, Angelita Cristine de Melo, Vinícius Silva Belo, Valéria Ernestânia Chaves
Although uric acid is not part of any definition of metabolic syndrome, a number of studies have shown strong associations between the concentration of uric acid and metabolic syndrome or its components. The purpose of this systematic review with meta-analysis was to evaluate, using prospective interventional studies, the effects of allopurinol therapy and uric acid normalization on serum concentrations of triacylglycerol, total-cholesterol, LDL-cholesterol and HDL-cholesterol in hyperuricemic subjects. A systematic search of the PubMed and Scopus databases was performed following the guidelines described in the PRISMA statement...
July 25, 2017: Clinical Biochemistry
https://www.readbyqxmd.com/read/28742703/organ-preservation-in-ct2n0-rectal-cancer-after-neoadjuvant-chemoradiation-therapy-the-impact-of-radiation-therapy-dose-escalation-and-consolidation-chemotherapy
#5
Angelita Habr-Gama, Guilherme Pagin São Julião, Bruna Borba Vailati, Jorge Sabbaga, Patricia Bailão Aguilar, Laura Melina Fernandez, Sergio Eduardo Alonso Araújo, Rodrigo Oliva Perez
OBJECTIVE: To demonstrate the difference in organ-preservation rates and avoidance of definitive surgery among cT2N0 rectal cancer patients undergoing 2 different chemoradiation (CRT) regimens. BACKGROUND: Patients with cT2N0 rectal cancer are more likely to develop complete response to neoadjuvant CRT. Organ preservation has been considered an alternative treatment strategy for selected patients. Radiation dose-escalation and consolidation chemotherapy have been associated with increased rates of response and may improve chances of organ preservation among these patients...
July 24, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28719026/in-vitro-antiproliferative-and-antibacterial-activities-of-essential-oils-from-four-species-of-guatteria
#6
Anderson R Santos, Thalita Gilda S Benghi, Angelita Nepel, Francisco A Marques, Adriana Q Lobão, Marta Cristina T Duarte, Ana Lúcia T G Ruiz, João E Carvalho, Beatriz H L N S Maia
The essential oils extracted from four species of the genus Guatteria, G.australis, G. ferruginea, G. latifolia and G. sellowiana were analyzed. A total of 24, 22, 25 and 19 constituents of the oils from four species, respectively, were identified by GC-MS. These oils showed qualitative and quantitative differences. All the oils contained the oxygenated sesquiterpenes spathulenol (11.04 - 40.29%) and caryophyllene oxide (7.74 - 40.13%) as predominant constituents. Evaluation of antiproliferative activity of the essential oils showed strong selectivity (1...
July 18, 2017: Chemistry & Biodiversity
https://www.readbyqxmd.com/read/28704519/e2f1-somatic-mutation-within-mirna-target-site-impairs-gene-regulation-in-colorectal-cancer
#7
Camila M Lopes-Ramos, Bruna P Barros, Fernanda C Koyama, Paola A Carpinetti, Julia Pezuk, Nayara T S Doimo, Angelita Habr-Gama, Rodrigo O Perez, Raphael B Parmigiani
BACKGROUND: Genetic studies have largely concentrated on the impact of somatic mutations found in coding regions, and have neglected mutations outside of these. However, 3' untranslated regions (3' UTR) mutations can also disrupt or create miRNA target sites, and trigger oncogene activation or tumor suppressor inactivation. METHODS: We used next-generation sequencing to widely screen for genetic alterations within predicted miRNA target sites of oncogenes associated with colorectal cancer, and evaluated the functional impact of a new somatic mutation...
2017: PloS One
https://www.readbyqxmd.com/read/28704411/complete-factorial-design-to-adjust-ph-and-sugar-concentrations-in-the-inoculum-phase-of-ralstonia-solanacearum-to-optimize-p-3hb-production
#8
Karine Laste Macagnan, Mariane Igansi Alves, Amanda Ávila Rodrigues, Lígia Furlan, Rosane da Silva Rodrigues, Patrícia Diaz de Oliveira, Claire Tondo Vendruscolo, Angelita da Silveira Moreira
Poly(3-hydroxybutyrate) (P(3HB)) is a biodegradable plastic biopolymer that accumulates as lipophilic inclusions in the cytoplasm of some microorganisms. The biotechnological process by which P(3HB) is synthesized occurs in two phases. The first phase involves cell growth in a complex culture medium, while the second phase involves polymer accumulation in the presence of excess carbon sources. As such, the efficiency of the second phase depends on the first phase. The aim of this study was to evaluate culture media with different concentrations of sucrose and glucose and different pH values in the inoculum phase of Ralstonia solanacearum RS with the intention of identifying methods by which the biomass yield could be increased, subsequently enhancing the yield of P(3HB)...
2017: PloS One
https://www.readbyqxmd.com/read/28678960/aqueous-extract-of-psidium-guajava-leaves-phenolic-compounds-and-inhibitory-potential-on-digestive-enzymes
#9
Anderson A Simão, Tamara R Marques, Silvana Marcussi, Angelita D Corrêa
Leaves of Psidium guajava L. (guava) have been widely used in the popular way for prevention and treatment of various diseases. Thus, the objective of this study was to evaluate the inhibitory potential of leaves aqueous extract from three cultivars of P. guajava (Pedro Sato, Paluma and Século XXI) on α-amylase, α-glycosidase, lipase, and trypsin enzymes, in the presence or not of simulated gastric fluid and to determine the content of phenolic compounds by high performance liquid chromatography. All cultivars presented the same composition in phenolic compounds, but in different proportions...
June 29, 2017: Anais da Academia Brasileira de Ciências
https://www.readbyqxmd.com/read/28645916/structures-and-dynamics-of-hibernating-ribosomes-from-staphylococcus-aureus-mediated-by-intermolecular-interactions-of-hpf
#10
Iskander Khusainov, Quentin Vicens, Rustam Ayupov, Konstantin Usachev, Alexander Myasnikov, Angelita Simonetti, Shamil Validov, Bruno Kieffer, Gulnara Yusupova, Marat Yusupov, Yaser Hashem
In bacteria, ribosomal hibernation shuts down translation as a response to stress, through reversible binding of stress-induced proteins to ribosomes. This process typically involves the formation of 100S ribosome dimers. Here, we present the structures of hibernating ribosomes from human pathogen Staphylococcus aureus containing a long variant of the hibernation-promoting factor (SaHPF) that we solved using cryo-electron microscopy. Our reconstructions reveal that the N-terminal domain (NTD) of SaHPF binds to the 30S subunit as observed for shorter variants of HPF in other species...
July 14, 2017: EMBO Journal
https://www.readbyqxmd.com/read/28630569/leadership-preferences-of-adolescent-players-in-sport-influence-of-coach-gender
#11
Angelita B Cruz, Hyun-Duck Kim
The authors investigated the coaching behavior preferences and the relationships of these preferences with variables such as gender, type of sport, playing experience, competitive level, and coach gender among young athletes in the national badminton league. Participants were 167 elementary and high school badminton players (91 girls and 76 boys; age range = 9-18 years; M = 13.5 (SD = 2.22) years) competing in the badminton event of a national league. Players' preferences for coaching behavior were measured using athlete preference version of the LSS to evaluate the five dimensions of leadership behavior in a sporting context...
June 2017: Journal of Sports Science & Medicine
https://www.readbyqxmd.com/read/28623651/an-investigation-of-support-services-available-by-internet-searching-to-families-impacted-by-a-parent-s-cancer
#12
Julia Nellie Morris, Jeneva Ohan, Angelita Martini
OBJECTIVE: Throughout a parent's cancer diagnosis and treatment, families are likely to turn to the Internet to find social, emotional and informational support services. It is important professionals understand the content and availability of support discoverable through web searches. This study identified and described web-based information regarding support services offered to families when a parent has cancer. METHODS: Pre-defined key search terms were searched across two public web browsers for a period of 3 months...
June 16, 2017: Psycho-oncology
https://www.readbyqxmd.com/read/28622703/qualitative-determination-of-human-chorionic-gonadotropin-in-vaginal-washings-for-the-early-diagnosis-of-premature-rupture-of-fetal-membranes
#13
Camila Buziquia Dartibale, Nelson Shozo Uchimura, Luiz Nery, Angelita Polato Schumeish, Liza Yurie Teruya Uchimura, Rosangela Getirana Santana, Taqueco Teruya Uchimura
Purpose This study aimed to evaluate and validate the qualitative human chorionic gonadotropin β subunit (β-hCG) test of the vaginal fluid washings of pregnant women with premature rupture of fetal membranes (PROM). Methods Cross-sectional study of pregnant women between gestational weeks 24 and 39 who underwent consultations in one of our institutions. They were divided into two groups: group A (pregnant women clinically diagnosed with PROM) and group B (pregnant women without loss of amniotic liquid)...
July 2017: Revista Brasileira de Ginecologia e Obstetrícia
https://www.readbyqxmd.com/read/28591069/world-gastroenterology-organisation-global-guidelines-gerd-global-perspective-on-gastroesophageal-reflux-disease
#14
Richard Hunt, David Armstrong, Peter Katelaris, Mary Afihene, Abate Bane, Shobna Bhatia, Min-Hu Chen, Myung Gyu Choi, Angelita Cristine Melo, Kwong Ming Fock, Alex Ford, Michio Hongo, Aamir Khan, Leonid Lazebnik, Greger Lindberg, Maribel Lizarzabal, Thein Myint, Joaquim Prado Moraes-Filho, Graciela Salis, Jaw Town Lin, Raj Vaidya, Abdelmounen Abdo, Anton LeMair
No abstract text is available yet for this article.
July 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28589643/residual-risk-of-transmission-of-human-immunodeficiency-virus-and-hepatitis-c-virus-infections-by-blood-transfusion-in-northern-brazil
#15
Priscilla Cristina Moura Vieira, Letícia Martins Lamarão, Carlos Eduardo de Melo Amaral, Angelita Silva de Miranda Corrêa, Maria Salete Maciel de Lima, Katarine Antônia Dos Santos Barile, Karine Lisboa Damasceno de Almeida, Vinicius de Albuquerque Sortica, André Salim Kayath, Rommel Mario Rodríguez Burbano
BACKGROUND: Nucleic acid test (NAT) blood screening for human immunodeficiency virus (HIV) and hepatitis C virus (HCV) was introduced in northern Brazil in July 2012. There are several Brazilian articles that have evaluated transfusion transmission risks for HIV and HCV. However, to our knowledge, this article is the first to evaluate the impact of HIV and HCV NAT implementation for blood screening in northern Brazil. The aim of this study was to determine the prevalence and incidence rates of HIV and HCV among blood donors and to compare the residual risk of transfusion transmission of these infections, before (2009-2011) and after (2012-2014) NAT implementation...
August 2017: Transfusion
https://www.readbyqxmd.com/read/28582611/dynamic-dna-origami-device-for-measuring-compressive-depletion-forces
#16
Michael W Hudoba, Yi Luo, Angelita Zacharias, Michael G Poirier, Carlos E Castro
The ability to self-assemble nanodevices with programmed structural dynamics that can sense and respond to the local environment could enable transformative applications in fields including molecular robotics, nanomanufacturing, and nanomedicine. The responsive function of biomolecules is often driven by alterations in conformational distributions mediated by highly sensitive interactions with the local environment. Here, we mimic this approach by engineering inherent nanoscale structural dynamics (nanodynamics) into a DNA device that exhibits a distribution of conformations including two stable states separated by a transition state where the energy barrier height is on the scale of the thermal energy, kBT = 4...
July 25, 2017: ACS Nano
https://www.readbyqxmd.com/read/28555192/the-use-of-xanthan-gum-as-vaccine-adjuvant-an-evaluation-of-immunostimulatory-potential-in-balb-c-mice-and-cytotoxicity-in-vitro
#17
Rodrigo Andrade Schuch, Thaís Larré Oliveira, Thaís Farias Collares, Leonardo Garcia Monte, Guilherme Roig Inda, Odir Antonio Dellagostin, Claire Tondo Vendruscolo, Angelita da Silveira Moreira, Daiane Drawanz Hartwig
The successful production of new, safe, and effective vaccines that generate immunological memory is directly related to adjuvant feature, which is responsible for increasing and/or modulating the immune response. Several compounds display adjuvant activity, including carbohydrates. These compounds play important roles in the immune response, as well as having biocompatible properties in vaccine formulations. One such carbohydrate is xanthan gum, a polysaccharide that is produced by the plant-pathogenic bacterium Xanthomonas spp...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28501249/new-strategies-in-rectal-cancer
#18
REVIEW
Guilherme Pagin São Julião, Angelita Habr-Gama, Bruna Borba Vailati, Sergio Eduardo Alonso Araujo, Laura Melina Fernandez, Rodrigo Oliva Perez
In recent years, our understanding of rectal cancer has improved, including how locally advanced disease responds to chemotherapy and radiation. This has led to new innovations and advances in the treatment of rectal cancer, which includes organ-preserving strategies for responsive disease, and minimally invasive approaces for the performance of total mesorectal excision/protectomyh for persistently advanced disease. This article discusses new strategies for rectal cancer therapy, including Watch and Wait, local excision, minimally invasive proctectomy, and transanal total mesorectal excision particularly in the setting of preoperative multimodality treatment...
June 2017: Surgical Clinics of North America
https://www.readbyqxmd.com/read/28498001/abce1-a-special-factor-that-orchestrates-translation-at-the-crossroad-between-recycling-and-initiation
#19
Eder Mancera-Martínez, Jailson Brito Querido, Leos Shivaya Valasek, Angelita Simonetti, Yaser Hashem
For many years initiation and termination of mRNA translation have been studied separately. However, a direct link between these two isolated stages has been suggested by the fact that some initiation factors also control termination and can even promote ribosome recycling; i.e. the last stage where post-terminating 80 S ribosomes are split to start a new round of initiation. Notably, it is now firmly established that, among other factors, ribosomal recycling critically requires the NTPase ABCE1. However, several earlier reports have proposed that ABCE1 also somehow participates in the initiation complex assembly...
May 12, 2017: RNA Biology
https://www.readbyqxmd.com/read/28481852/baseline-t-classification-predicts-early-tumor-regrowth-after-nonoperative-management-in-distal-rectal-cancer-after-extended-neoadjuvant-chemoradiation-and-initial-complete-clinical-response
#20
Angelita Habr-Gama, Guilherme Pagin São Julião, Joaquim Gama-Rodrigues, Bruna Borba Vailati, Cinthia Ortega, Laura Melina Fernandez, Sérgio Eduardo Alonso Araújo, Rodrigo Oliva Perez
BACKGROUND: Selected patients with rectal cancer and complete clinical response after neoadjuvant chemoradiation have been managed nonoperatively with acceptable outcomes. However, ≈20% of these patients will develop early tumor regrowth. Identification of these patients could select candidates for more intensive follow-up. OBJECTIVE: The purpose of this study was to investigate the influence of baseline radiological T classification on recurrences after a complete clinical response managed nonoperatively after chemoradiation...
June 2017: Diseases of the Colon and Rectum
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