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https://www.readbyqxmd.com/read/29049818/dor-procedure-for-pulmonary-atresia-with-intact-ventricular-septum-in-an-infant
#1
Yoonjin Kang, Jae Gun Kwak, Eung Rae Kim, Woong-Han Kim
Pulmonary atresia with intact ventricular septum and right ventricle-dependent coronary circulation confers a high risk for myocardial infarction and complications of ischaemia, including left ventricle aneurysms. We describe an infant with pulmonary atresia with intact ventricular septum and right ventricle-dependent coronary circulation and a left ventricle apical aneurysm who successfully underwent the Dor procedure and a subsequent Fontan operation. Surgery for postinfarction left ventricle aneurysm can be considered in infants...
September 2, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29049804/preoperative-statins-as-modifiers-of-cardiac-and-inflammatory-outcomes-following-coronary-artery-bypass-graft-surgery-a-meta-analysis
#2
JingHui An, FengWu Shi, Su Liu, Jie Ma, QianLi Ma
Early postoperative cardiac complications of coronary artery bypass graft surgery, such as atrial fibrillation (AF) or myocardial infarction (MI), may be beneficially modulated by preoperative statins, involving their anti-inflammatory effects. There is uncertainty on the clinical merit of statin pretreatment. Addressing this, we conducted a meta-analysis of early cardiac complications and inflammatory markers following statin pretreatment in coronary artery bypass graft surgery. A search of Medline and Cochrane databases was undertaken to identify suitable studies...
July 26, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29049704/mortality-and-morbidity-of-patients-on-the-waiting-list-for-coronary-artery-bypass-graft-surgery
#3
Viviane Belidio Pinheiro da Fonseca, Andrea De Lorenzo, Bernardo Rangel Tura, Felipe José Monassa Pittella, Antônio Sérgio Cordeiro da Rocha
OBJECTIVES: The public health care system in Brazil has extensive waiting lists of patients requiring complex operations such as coronary artery bypass grafting (CABG). The purpose of this study was to identify the mortality and morbidity rates of the patients awaiting CABG and identify predictors of adverse events and their association with perioperative outcomes. METHODS: We conducted a retrospective analysis of outpatient medical records of patients referred for this elective procedure in Rio de Janeiro, Brazil...
August 24, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29049690/surgical-treatment-of-postinfarction-ventricular-septal-defect-risk-factors-and-outcome-analysis
#4
Marek Pojar, Jan Harrer, Nedal Omran, Zdenek Turek, Jana Striteska, Jan Vojacek
OBJECTIVES: Postinfarction ventricular septal defect is a serious mechanical complication of acute myocardial infarction associated with high postoperative mortality. The aim of this study was to review our experience with surgical repair of postinfarction ventricular septal defect and to identify predictors of early and late outcomes. METHODS: Thirty-nine patients (19 men and 20 women, mean age 68.4 ± 9.9 years) with postinfarction ventricular septal defect who underwent surgical repair at our institution between 1996 and 2016 were retrospectively evaluated...
August 24, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29049536/preoperative-syntax-score-to-assess-the-late-outcomes-after-coronary-endarterectomy-for-the-diffusely-diseased-left-anterior-descending-artery
#5
Kosaku Nishigawa, Toshihiro Fukui, Shuichiro Takanashi
OBJECTIVES: To evaluate whether the preoperative Synergy between Percutaneous Coronary Intervention with TAXUS and Cardiac Surgery (SYNTAX) score was associated with late outcomes of coronary endarterectomy (CE) for the diffusely diseased left anterior descending artery (LAD). METHODS: We retrospectively analysed 205 of 212 patients undergoing CE for the diffusely diseased LAD between September 2004 and May 2016, excluding 2 patients without preoperative angiographic data and 5 redo cases...
June 16, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29049508/outcomes-in-women-and-minorities-compared-with-white-men-1-year-after-everolimus-eluting-stent-implantation-insights-and-results-from-the-platinum-diversity-and-promus-element-plus-post-approval-study-pooled-analysis
#6
Wayne Batchelor, David E Kandzari, Scott Davis, Luis Tami, John C Wang, Islam Othman, Osvaldo S Gigliotti, Amir Haghighat, Sarabjeet Singh, Mario Lopez, Gregory Giugliano, Phillip A Horwitz, Jaya Chandrasekhar, Paul Underwood, Craig A Thompson, Roxana Mehran
Importance: There exist limited outcomes data for women and minorities after contemporary percutaneous coronary intervention (PCI). Objective: To examine 1-year outcomes in women and minorities vs white men after PCI with everolimus-eluting stents. Design, Settings, and Participants: The PLATINUM Diversity study was a single-arm study enrolling women and minorities. Patient-level pooling with the PROMUS Element Plus Post-Approval Study was prespecified...
October 18, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/29049200/subclinical-atherosclerosis-and-history-of-cardiovascular-events-in-italian-patients-with-rheumatoid-arthritis-results-from-a-cross-sectional-multicenter-girrcs-gruppo-italiano-di-ricerca-in-reumatologia-clinica-e-sperimentale-study
#7
Piero Ruscitti, Domenico Paolo Emanuele Margiotta, Federica Macaluso, Daniela Iacono, Francesca D'Onofrio, Giacomo Emmi, Fabiola Atzeni, Marcella Prete, Federico Perosa, Piercarlo Sarzi-Puttini, Lorenzo Emmi, Francesco Paolo Cantatore, Giovanni Triolo, Antonella Afeltra, Roberto Giacomelli, Gabriele Valentini
Several studies have pointed out a significant association between rheumatoid arthritis (RA) and accelerated atherosclerosis. At the best of our knowledge, no such study has been carried out in a large Italian series and, in this study, we aimed to investigate the prevalence of both subclinical atherosclerosis and history of cardiovascular events (CVEs), in patients consecutively admitted from January 1, 2015 to December 31, 2015 to Rheumatology Units throughout the whole Italy.Centers members of GIRRCS (Gruppo Italiano di Ricerca in Reumatologia Clinica e Sperimentale) were invited to enrol patients consecutively admitted from January 1, 2015 to December 31, 2015 and satisfying American College of Rheumatology/ European League Against Rheumatism criteria for RA and to investigate each of them for: traditional cardiovascular risk factors: sex, age, smoking habit, total cholesterol, triglycerides, glycaemia, high blood pressure, metabolic syndrome (MS), type 2 diabetes (T2D); RA features: disease duration as assessed from the first symptom, disease activity as evaluated by DAS28, radiographic damage as assessed by hands and feet x-ray, and previous joint surgery; prevalence of both subclinical atherosclerosis and history of CVEs...
October 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29049073/postoperative-outcomes-in-obstructive-sleep-apnea-patients-undergoing-cardiac-surgery-a-systematic-review-and-meta-analysis-of-comparative-studies
#8
Mahesh Nagappa, George Ho, Jayadeep Patra, Jean Wong, Mandeep Singh, Roop Kaw, Davy Cheng, Frances Chung
BACKGROUND: Obstructive sleep apnea (OSA) is a common comorbidity in patients undergoing cardiac surgery and may predispose patients to postoperative complications. The purpose of this meta-analysis is to determine the evidence of postoperative complications associated with OSA patients undergoing cardiac surgery. METHODS: A literature search of Cochrane Database of Systematic Reviews, Medline, Medline In-process, Web of Science, Scopus, EMBASE, Cochrane Central Register of Controlled Trials, and CINAHL until October 2016 was performed...
October 17, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29047356/non-syndromic-cardiac-progeria-in-a-patient-with-the-rare-pathogenic-p-asp300asn-variant-in-the-lmna-gene
#9
Ali J Marian
BACKGROUND: Mutations in LMNA gene, encoding Lamin A/C, cause a diverse array of phenotypes, collectively referred to as laminopathies. The most common manifestation is dilated cardiomyopathy (DCM), occurring in conjunction with variable skeletal muscle involvement but without involvement of the coronary arteries. Much less commonly, LMNA mutations cause progeroid syndromes, whereby an early-onset coronary artery disease (CAD) is the hallmark of the disease. We report a hitherto unreported compound cardiac phenotype, dubbed as "non-syndromic cardiac progeria", in a young patient who carried a rare pathogenic variant in the LMNA gene and developed progressive degeneration of various cardiac structures, as seen in the elderly...
October 18, 2017: BMC Medical Genetics
https://www.readbyqxmd.com/read/29042955/intramyocardial-delivery-of-bfgf-with-a-biodegradable-and-thermosensitive-hydrogel-improves-angiogenesis-and-cardio-protection-in-infarcted-myocardium
#10
Hongling Zhu, Xiaoyan Li, Mingjie Yuan, Weiguo Wan, Miaoyang Hu, Xiaoding Wang, Xuejun Jiang
Basic fibroblast growth factor (bFGF), a known angiogenic factor, may provide a potential strategy for the treatment of myocardial infarction (MI), but it is limited by a relatively short half-life. Dex-PCL-HEMA/PNIPAAm hydrogel provides a reservoir for the controlled release of growth factors. The aim of the current study was to evaluate the effects of bFGF incorporated into a Dex-PCL-HEMA/PNIPAAm hydrogel on angiogenesis and cardiac health in a rat model of acute MI, induced by coronary artery ligation. Phosphate-buffered solution (PBS group), Dex-PCL-HEMA/PNIPAAm hydrogel (Gel group), bFGF in phosphate-buffered solution (bFGF group) or bFGF in hydrogel (Gel + bFGF group) was injected into a peri-infarcted area of cardiac tissue immediately following MI...
October 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29042076/perioperative-outcomes-after-reoperative-carotid-endarterectomy-are-worse-than-expected
#11
Brianna M Krafcik, Thomas W Cheng, Alik Farber, Jeffrey A Kalish, Denis Rybin, Gheorghe Doros, Jeffrey J Siracuse
OBJECTIVE: Reoperative carotid endarterectomy (CEA) can be technically challenging because of significant scarring as a consequence of the initial CEA procedure. There are limited data that describe outcomes after reoperative CEA, and as such, our goal was to determine the effect of reoperative CEA on perioperative outcomes. METHODS: The American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) database was queried for patients undergoing index and reoperative CEA between 2005 and 2014...
October 14, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29037313/prevalence-of-ischemic-heart-disease-and-associated-factors-in-patients-with-rheumatoid-arthritis-in-southern-brazil
#12
Rafael Kmiliauskis Santos Gomes, Ana Carolina Albers, Ana Isadora Pianowski Salussoglia, Ana Maria Bazzan, Luana Cristina Schreiner, Mateus Oliveira Vieira, Patrícia Giovana da Silva, Patrícia Helena Machado, Cynthia Mara da Silva, Mauro Marcelo Mattos, Moacyr Roberto Cuce Nobre
OBJECTIVE: To estimate the prevalence of ischemic heart disease and associated factors in patients with rheumatoid arthritis. METHODS: A cross-sectional study using the American College of Rheumatology diagnostic criteria in order to select patients seen at primary or secondary health care units in Blumenau, Santa Catarina, Southern Brazil, in 2014. The presence of ischemic heart disease was defined as an acute myocardial infarction with percutaneous coronary intervention or coronary artery bypass graft surgery that has occurred after diagnosis...
September 2017: Revista Brasileira de Reumatologia
https://www.readbyqxmd.com/read/29036976/-comparison-of-perioperative-serum-thrombomodulin-levels-in-patients-underwent-off-pump-coronary-artery-bypass-grafting-with-and-without-cardiogenic-shock
#13
L Zhang, C Wang, T X Gu, C M Lu, Z W Wang
Objective: To observe the perioperative changes of serum thrombomodulin in patients with and without cardiogenic shock undergoing off-pump coronary artery bypass grafting surgery. Methods: A total of 66 patients with coronary artery disease who underwent off-pump coronary artery bypass grafting surgery between June and December 2015 in our hospital were included in this study.The patients were divided into non-cardiogenic shock group (n=51) and shock group (n=15) according to the absence or presence of cardiogenic shock...
September 24, 2017: Zhonghua Xin Xue Guan Bing za Zhi
https://www.readbyqxmd.com/read/29035780/long-non-coding-rnas-in-the-atherosclerotic-plaque
#14
Serdal Arslan, Öcal Berkan, Torkia Lalem, Nil Özbilüm, Sabahattin Göksel, Özge Korkmaz, Nilgün Çetin, Yvan Devaux
BACKGROUND AND AIMS: Genetic and environmental factors are important components of the development of atherosclerosis. Long non-coding RNA (lncRNAs) have emerged as regulators of multiple pathophysiological pathways in the cardiovascular system. Here, we investigated potential associations between lncRNAs and atherosclerosis. METHODS: Tissue samples from atherosclerotic coronary artery plaques and non-atherosclerotic internal mammary artery were obtained from 20 patients during coronary artery bypass surgery...
October 7, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/29032753/halogenated-agents-and-cardiovascular-surgery-has-mortality-really-decreased
#15
Giovanni Landoni, Juan Carlos Lopez-Delgado, Chiara Sartini, Simona Tamà, Alberto Zangrillo
Halogenated anesthetic agents (desflurane, isoflurane and sevoflurane) may have cardioprotective properties at therapeutic doses against myocardial intraoperative ischemia-reperfusion injury. Cardioprotection mechanisms are related to mitochondrial and anti-apoptotic signaling pathways. Experimental and human studies have proven that their use may reduce morbidity and mortality in the setting of cardiac surgery, including a reduction in myocardial infarct size and mechanical ventilation needs. On the contrary, total intra-venous propofol based anesthesia may be detrimental...
October 10, 2017: Current Vascular Pharmacology
https://www.readbyqxmd.com/read/29030377/spontaneous-closure-of-ventricular-septal-perforation-following-percutaneous-coronary-intervention-for-acute-myocardial-infarction
#16
Tetsuo Yamanaka, Toru Fukatsu, Yoshimaro Ichinohe, Yasunobu Hirata
We report on an 84-year-old woman with anteroseptal acute myocardial infarction. Emergency coronary angiography revealed the occlusion of proximal left anterior descending artery without collateral circulation, and percutaneous coronary intervention was performed. Two drug eluting stents were implanted, and the procedure was concluded with thrombolysis in myocardial infarction grade 3 without complications. Postoperatively, no murmur was audible on auscultation and no shunt flow was observed on transthoracic echocardiography (TTE), and normal blood pressure was maintained...
October 13, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29029526/percutaneous-coronary-intervention-using-drug-eluting-stents-versus-coronary-artery-bypass-graft-surgery-in-left-main-coronary-artery-disease-an-updated-meta-analysis-of-randomized-clinical-trials
#17
Lei Gao, Yuqi Liu, Zhijun Sun, Yabin Wang, Feng Cao, Yundai Chen
OBJECTIVES: To compare the safety and efficacy of percutaneous coronary intervention (PCI) using drug-eluting stent (DES) and coronary artery bypass graft (CABG) for the treatment of left main coronary artery (LMCA) disease. BACKGROUND: Several new randomized trials have recently examined the clinical outcomes of PCI and CABG in LMCA disease. However, the results of these studies were inconsistent. MATERIALS AND METHODS: We searched five online electronic databases to identify all the randomized clinical trials assessing the outcomes of PCI using DES and CABG in patients with LMCA...
September 12, 2017: Oncotarget
https://www.readbyqxmd.com/read/29028739/association-of-the-syntax-score-ii-with-cardiac-rupture-in-patients-with-st-segment-elevation-myocardial-infarction-undergoing-a-primary-percutaneous-coronary-intervention
#18
Ibrahim Rencuzogullari, Metin Çağdaş, Yavuz Karabağ, Süleyman Karakoyun, Mahmut Yesin, Mustafa O Gürsoy, Sabri Seyis, İnanç Artaç, Doğan İliş, Süleyman Ç Efe, İbrahim H Tanboğa
BACKGROUND: Despite advances in reperfusion strategies, medical therapy, and emergent surgery, cardiac rupture (CR) is still a major lethal complication. Numerous parameters have been found to be associated with CR development after a primary percutaneous coronary intervention (pPCI). SYNTAX Score (SS) and SYNTAX Score II (SSII) have been studied in ST-segment elevation myocardial infarction (STEMI) patients, and higher scores have been associated with higher mortality. However, the relationship between CR and SSII is unclear...
October 12, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/29021267/association-of-neighborhood-socioeconomic-context-with-participation-in-cardiac-rehabilitation
#19
Justin M Bachmann, Shi Huang, Deepak K Gupta, Loren Lipworth, Michael T Mumma, William J Blot, Elvis A Akwo, Sunil Kripalani, Mary A Whooley, Thomas J Wang, Matthew S Freiberg
BACKGROUND: Cardiac rehabilitation (CR) is underutilized in the United States, with fewer than 20% of eligible patients participating in CR programs. Individual socioeconomic status is associated with CR utilization, but data regarding neighborhood characteristics and CR are sparse. We investigated the association of neighborhood socioeconomic context with CR participation in the SCCS (Southern Community Cohort Study). METHODS AND RESULTS: The SCCS is a prospective cohort study of 84 569 adults in the southeastern United States from 2002 to 2009, 52 117 of whom have Medicare or Medicaid claims...
October 11, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29019754/abnormalities-of-the-coronary-arteries-in-children-looking-beyond-the-origins
#20
Lauren J Saling, Demetrios A Raptis, Keyur Parekh, Toby A Rockefeller, Elizabeth F Sheybani, Sanjeev Bhalla
Coronary arterial abnormalities are uncommon findings in children that have profound clinical implications. Although anomalies of the coronary origins are well described, there are many other disease processes that affect the coronary arteries. Immune system-mediated diseases (eg, Kawasaki disease, polyarteritis nodosa, and other vasculiditides) can result in coronary arterial aneurysms, strictures, and abnormal tapering of the vessels. Because findings at imaging are an important component of diagnosis in these diseases, the radiologist's understanding of them is essential...
October 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
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