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second tumors and stems cell trasplantation

M D Caballero, J A Pérez-Simón, A Iriondo, J J Lahuerta, J Sierra, J Marín, M Gandarillas, R Arranz, J Zuazu, V Rubio, A Fernández de Sevilla, E Carreras, J García-Conde, J García-Laraña, C Grande, A Sureda, M J Vidal, J Rifón, C Pérez-Equiza, R Varela, J M Moraleda, J C García Ruíz, C Albó, R Cabrera, J F San Miguel, E Conde
BACKGROUND: The purpose of this study was to analyse the results and prognostic factors influencing overall survival (OS) and disease-free survival (DFS) in 452 patients diagnosed with diffuse large cell lymphomas (DLCL) treated with high-dose therapy (HDT) included in the Grupo Español de Linfomas/Trasplante Autólogo de Médula Osea (GEL-TAMO) Spanish registry. PATIENTS AND METHODS: At transplantation, median age was 42 years (range 15-73), 146 patients (32%) were transplanted in first complete remission (1st CR), 19% in second CR (2nd CR) and 47% had active disease: sensitive disease in 157 (35%) patients [95 were in first partial remission (1st PR) and 62 in second PR (2nd PR)] and refractory disease in 55 (12%) patients...
January 2003: Annals of Oncology: Official Journal of the European Society for Medical Oncology
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