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ablation microwave

N Pinsker, M Papoulas, M Sodergren, P Harrison, N Heaton, K Menon
Introduction A bronchobiliary fistula (BBF) following liver directed therapy (resection/ablation) is a rare complication in which an abnormal communication between the biliary tract and bronchial tree is formed. This case report describes the successful management of a persistent BBF following multiple liver wedge resections and microwave ablation in a patient with a metastatic neuroendocrine tumour of the terminal ileum. Case history A 69-year-old man presented with unexplained weight loss and was subsequently diagnosed with a neuroendocrine tumour of the terminal ileum and liver metastasis...
March 15, 2018: Annals of the Royal College of Surgeons of England
Wouter J Heerink, A Millad Solouki, Rozemarijn Vliegenthart, Simeon J S Ruiter, Egbert Sieders, Matthijs Oudkerk, Koert P de Jong
OBJECTIVES: To study the ratio of ablation zone volume to applied energy in computed tomography (CT)-guided radiofrequency ablation (RFA) and microwave ablation (MWA) in patients with hepatocellular carcinoma (HCC) in a cirrhotic liver and in patients with colorectal liver metastasis (CRLM). METHODS: In total, 90 liver tumors, 45 HCCs in a cirrhotic liver and 45 CRLMs were treated with RFA or with one of two MWA devices (MWA_A and MWA_B), resulting in 15 procedures for each tumor type, per device...
March 13, 2018: European Radiology
Jian-Ming Hu, Huang-Tao Sun
BACKGROUND: To find potential serum biomarkers of microwave ablation (MWA) for treatment of human lung cancer by1 H nuclear magnetic resonance (NMR)-based metabolomics analysis. METHODS: Serum specimens collected from 43 healthy individuals, 39 patients with advanced non-small cell lung cancer (NSCLC) and 38 NSCLC patients treated with MWA, were subjected to1 H NMR-based metabolomics analysis. Partial least squares discriminant analysis was used to analyze the data...
March 12, 2018: Radiation Oncology
Xia Yang, Xin Ye, Licheng Zhang, Dianzhong Geng, Zhenli Du, Guohua Yu, Haipeng Ren, Jiao Wang, Guanghui Huang, Zhigang Wei, Yang Ni, Wenhong Li, Xiaoying Han
BACKGROUND: The study was conducted to retrospectively evaluate the safety and effectiveness of computed tomography (CT)-guided percutaneous microwave ablation (MWA) for peripheral non-small cell lung cancer (NSCLC) in 11 patients with a single lung after pneumonectomy. METHODS: From May 2011 to March 2015, 11 single-lung patients (8 men and 3 women; mean age 60.3 years, range 46-71) with peripheral NSCLC underwent 12 sessions of MWA. Eleven tumors measuring 13-52 mm (mean 30...
March 12, 2018: Thoracic Cancer
Lin Zheng, Hai-Liang Li, Chen-Yang Guo, Su-Xia Luo
Objective: To evaluate the efficacy and prognostic factors associated with transcatheter arterial chemoembolization (TACE) combined with microwave ablation (MWA) versus TACE alone for a large solitary or multinodular hepatocellular carcinomas (HCCs). Materials and Methods: This retrospective study involved 258 patients with a large solitary or multinodular HCCs (not more than 10 tumors) who underwent TACE + MWA (n = 92) or TACE alone (n = 166) between July 2011 and April 2015...
March 2018: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
Shaoyong Peng, Pinzhu Huang, Huichuan Yu, Yanlin Wen, Yanxin Luo, Xiaolin Wang, Jiaming Zhou, Si Qin, Tuoyang Li, Yao Chen, Guangjian Liu, Meijin Huang
Thermal ablation is an alternative treatment for colorectal cancer liver metastasis (CRLM). However, prognostic factors in patients with CRLM who have undergone microwave ablation (MWA) have not been clearly defined. Therefore, this study aimed to analyze the risk factors associated with early recurrence in patients with CRLM treated with MWA.Herein, we retrospectively analyzed data for 140 patients with CRLM who underwent MWA from 2013 to 2015 in our institution. Patients were grouped by median pretreatment carcinoembryonic antigen (CEA) level into the high CEA level (>3...
March 2018: Medicine (Baltimore)
Yan Zhou, Xiaolin Xu, Jianmin Ding, Xiang Jing, Fengmei Wang, Yandong Wang, Peng Wang
Aims: Thermal ablation can evoke an immune response, which may have effects on the prognosis of patients with hepatocellular carcinoma (HCC). Our aim is to investigate the changes of circulating T-cell subsets after microwave ablation (MWA) and to explore the risk factors of tumor recurrence in patients with hepatitis B virus (HBV)-related HCC. Methods: Thirty patients with HBV-related HCC were enrolled in this study. The blood samples were collected both before and after MWA (24 h, 72 h, and 1 month after MWA)...
January 2018: Journal of Cancer Research and Therapeutics
Matthias H M Klose, Sarah Theiner, Christoph Kornauth, Samuel M Meier-Menches, Petra Heffeter, Walter Berger, Gunda Koellensperger, Bernhard K Keppler
Laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS) was used to study the spatial distribution of two metallodrugs with anticancer activities in vivo, namely the organoruthenium plecstatin-1 (1) and its isosteric osmium analogue (2), in liver, kidneys, muscles and tumours of treated mice bearing a CT-26 tumour after single-dose i.p. administration. To the best of our knowledge, this is the first time that the spatial distribution of an osmium drug candidate has been investigated using LA-ICP-MS in tissues...
March 7, 2018: Metallomics: Integrated Biometal Science
Anna Maria Ierardi, Valeria Savasi, Salvatore Alessio Angileri, Mario Petrillo, Sara Sbaraini, Antonio Pinto, Francesco Hanozet, Anna Maria Marconi, Gianpaolo Carrafiello
Uterine fibroids are the most common benign pelvic tumor of the female genital tract and tend to increase with age; they cause menorrhagia, dysmenorrhea, pelvic pressure symptoms, back pain, and subfertility. Currently, the management is based mainly on medical or surgical approaches. The nonsurgical and minimally invasive therapies are emerging approaches that to the state of the art include uterine artery embolization (UAE), image-guided thermal ablation techniques like magnetic resonance-guided focused ultrasound surgery (MRgFUS) or radiofrequency ablation (RF), and percutaneous microwave ablation (PMWA)...
2018: BioMed Research International
Robert J Lewandowski, Riad Salem
No abstract text is available yet for this article.
March 1, 2018: Lancet. Gastroenterology & Hepatology
Naïk Vietti Violi, Rafael Duran, Boris Guiu, Jean-Pierre Cercueil, Christophe Aubé, Antonia Digklia, Isabelle Pache, Pierre Deltenre, Jean-François Knebel, Alban Denys
BACKGROUND: Radiofrequency ablation is the recommended treatment for patients with hepatocellular carcinoma who have lesions smaller than 3 cm and are therefore not candidates for surgery. Microwave ablation is a more recent technique with certain theoretical advantages that have not yet been confirmed clinically. We aimed to compare the efficacy of both techniques in the treatment of hepatocellular carcinoma lesions of 4 cm or smaller. METHODS: We did a randomised controlled, single-blinded phase 2 trial at four tertiary university centres in France and Switzerland...
March 1, 2018: Lancet. Gastroenterology & Hepatology
Taylor Ibelli, Sarah Templeton, Nicole Levi-Polyachenko
Recovery from systemic or local bacterial infections can be lengthy and costly, with the clinical challenges being further complicated when bacteria acquire resistance to current antibiotics. Hyperthermia offers new mechanisms for removing bacteria via ablation, or sensitising them to chemical agents. The first part of this review provides a background on the bacterial biofilms, their response to hyperthermia, and acquired resistance to antibiotics, followed by the clinical challenges they present in managing infections associated with soft tissues and biomedical implants...
March 2018: International Journal of Hyperthermia
Marco Solbiati, Katia M Passera, S Nahum Goldberg, Alessandro Rotilio, Tiziana Ierace, Vittorio Pedicini, Dario Poretti, Luigi Solbiati
AIM: To evaluate a novel contrast-enhanced cone-beam computed tomography (CE-CBCT) registration method for accurate immediate assessment of ablation outcomes. MATERIALS AND METHODS: Contrast-enhanced computed tomography (CECT) was registered with CE-CBCT by applying semiautomatic landmark registration followed by automatic affine and non-rigid registration to correct for respiratory phase differences and liver deformation. This scheme was retrospectively applied to 30 patients who underwent 38 percutaneous microwave liver ablations...
February 28, 2018: Cardiovascular and Interventional Radiology
Hiroshi Kodama, Eisuke Ueshima, Song Gao, Sebastien Monette, Lee-Ronn Paluch, Kreg Howk, Joseph P Erinjeri, Stephen B Solomon, Govindarajan Srimathveeravalli
PURPOSE: To assess the impact of duration of energy delivery on adverse events (AEs) and heat sink effects during high power microwave ablation (MWA) of normal swine lung. MATERIALS AND METHODS: High power (100 Watts) MWA was performed with short (2 minutes, 18 ablations) or long (10 minutes, 9 ablations) duration of energy delivery in unilateral lung of swine (n = 10). CT imaging was done prior to sacrifice at 2 or 28 days post-treatment, with additional imaging at 7 and 14 days for the latter cohort...
February 28, 2018: International Journal of Hyperthermia
Tomoki Ryu, Yuko Takami, Yoshiyuki Wada, Masaki Tateishi, Hajime Matsushima, Munehiro Yoshitomi, Kazuhiro Mikagi, Hideki Saitsu
BACKGROUND AND AIM: The effects of achieving sustained virological response (SVR) on recurrence and survival after curative treatment in patients with hepatitis virus C (HCV)-related hepatocellular carcinoma (HCC) is unclear. This study examined the influence of SVR achievement by interferon therapy before HCC occurrence on recurrence and survival. METHODS: This retrospective study included 518 patients who underwent surgical microwave ablation for initial HCV-related HCC between January 2001 and December 2015...
February 27, 2018: Hepatology International
Kyohei Kanematsu, Yuki Suematsu, Shunsuke Yamagishi, Miyuki Takahashi, Hiroyuki Saito, Mao Nakayama, Michiko Fukabori, Kazuhiko Wakabayashi, Yutaka Ito
We report 2 cases of prolonged survival achieved with surgical resection and multidisciplinary therapy for acinar cell carcinoma of the pancreas with liver metastases.Case 1: The patient was a 55-year-old woman.She presented with upper right abdominal pain and anemia.We diagnosed a tumor originating from the pancreas and multiple liver metastases.To avoid death caused by bleeding from the tumor, we performed pancreaticoduodenectomy and right-hemi hepatectomy, and a rapid diagnosis of acinar cell carcinoma of the pancreas was confirmed intraoperatively...
February 2018: Gan to Kagaku Ryoho. Cancer & Chemotherapy
Kimberly A Maciolek, E Jason Abel, Sara L Best, Hamid Emamekhoo, Sarah L Averill, Timothy J Ziemlewicz, Meghan G Lubner, J Louis Hinshaw, Fred T Lee, Shane A Wells
PURPOSE: The purpose of the article is to evaluate the safety and oncologic efficacy of microwave ablation for metastatic renal cell carcinoma (mRCC). MATERIALS AND METHODS: From September 2011 to December 2016, 33 mRCC were ablated in 18 patients using percutaneous microwave ablation. Sites of mRCC include retroperitoneum (n = 12), contralateral kidney (n = 6), liver (n = 6), lung (n = 5), adrenal gland (n = 5). Technical success, local, and distant tumor progression, and complications were assessed at immediate and follow-up imaging...
February 20, 2018: Abdominal Radiology
Robbert S Puijk, Alette H Ruarus, Hester J Scheffer, Laurien G P H Vroomen, Aukje A J M van Tilborg, Jan J J de Vries, Ferco H Berger, Petrousjka M P van den Tol, Martijn R Meijerink
Liver tumour ablation nowadays represents a routine treatment option for patients with primary and secondary liver tumours. Radiofrequency ablation and microwave ablation are the most widely adopted methods, although novel techniques, such as irreversible electroporation, are quickly working their way up. The percutaneous approach is rapidly gaining popularity because of its minimally invasive character, low complication rate, good efficacy rate, and repeatability. However, matched to partial hepatectomy and open ablations, the issue of ablation site recurrences remains unresolved and necessitates further improvement...
February 2018: Canadian Association of Radiologists Journal, Journal L'Association Canadienne des Radiologistes
Changwen Li, Cuiying Li, Han Ge, Mengdi Liang, Ge Ma, Lijun Ling, Hong Pan, Haiyan Gong, Hui Xie, Qiang Ding, Wenbin Zhou, Shui Wang
PURPOSE: To determine thecharacteristicsof ultrasound (US) imaging of completelyablated cases and theeffects of duration and clinical experience on accurate microwave ablation (MWA) for the treatment of benign breast tumours. METHODS: With written informed consent and approval of the institutional ethics committee, patients with symptomatic or palpable benign breast tumours (longest diameter, 7-32mm), to whom MWA (2450MHz) was performed, were enrolled in this prospective nonrandomized study...
February 19, 2018: International Journal of Hyperthermia
Amélie Loriaud, Alban Denys, Olivier Seror, Naik Vietti Violi, Antonia Digklia, Rafael Duran, Hervé Trillaud, Arnaud Hocquelet
PURPOSE: To compare overall local tumor progression (OLTP), defined as the failure of primary ablation or local tumor progression, with single applicator monopolar RFA, microwave ablation (MWA), cluster-RFA and multibipolar radiofrequency (mbpRFA) in the treatment of HCC≤5cm abutting large vessels (≥3mm). METHOD AND MATERIALS: This multicenter, retrospective, per-nodule study was performed from 2007 to 2015. The study was approved by the ethics review board, and informed consent was waived...
February 18, 2018: International Journal of Hyperthermia
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