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https://www.readbyqxmd.com/read/29352659/microwave-ablation-provides-better-survival-than-liver-resection-for-hepatocellular-carcinoma-in-patients-with-borderline-liver-function-application-of-albi-score-to-patient-selection
#1
Charing C N Chong, Kit-Fai Lee, Cheuk-Man Chu, Anthony W H Chan, John Wong, Stephen L Chan, Hon-Ting Lok, Andrew K Y Fung, Anthony K W Fong, Yue S Cheung, Simon C H Yu, Philip Johnson, Paul B S Lai
BACKGROUND: Studies comparing microwave ablation (MWA) and liver resection are lacking. This study evaluates the survival of patients with hepatocellular carcinoma (HCC) treated with liver resection or MWA and the role of Albumin-Bilirubin (ALBI) score in patient selection for treatments. METHODS: This is a retrospective analysis of patients who received curative liver resection or MWA for HCC. Propensity score matching was used at a 1:1 ratio. The value of ALBI grade for patient selection was evaluated...
January 15, 2018: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29344224/long-term-outcomes-of-microwave-endometrial-ablation-for-treatment-of-patients-with-menorrhagia-a-retrospective-cohort-study
#2
Kohei Nakamura, Kentaro Nakayama, Kaori Sanuki, Toshiko Minamoto, Tomoka Ishibashi, Emi Sato, Hitomi Yamashita, Masako Ishikawa, Satoru Kyo
This study aimed to describe the long-term outcomes of patients with menorrhagia treated with microwave endometrial ablation (frequency, 2.45 GHz), as well as to identify factors associated with recurrence or re-surgery. This retrospective cohort study was conducted from 2007 to 2015 at Shimane University Hospital in Japan. Patients with severe menorrhagia and a desire to preserve their uterus were included in the study. Clinical factors associated with recurrence of menorrhagia or re-surgery were analyzed with a multivariable logistic regression model...
December 2017: Oncology Letters
https://www.readbyqxmd.com/read/29337089/thermal-field-distributions-of-ablative-experiments-using-cyst-mimicking-phantoms-comparison-of-microwave-and-radiofrequency-ablation
#3
Xiao-Wen Huang, Fang Nie, Zeng-Cheng Wa, Hang-Tong Hu, Qing-Xiu Huang, Huan-Ling Guo, Qiao Zheng, Xiao-Yan Xie, Wei Wang, Ming-De Lu
RATIONALE AND OBJECTIVES: The objective of this study was to explore the thermal field distribution of cystic lesions undergoing microwave ablation (MWA) and radiofrequency ablation (RFA) using in vitro phantoms. MATERIALS AND METHODS: Cyst-mimicking lesions filled with sodium chloride (NaCl) solution in acrylamide phantoms were treated with MWA and RFA in vitro. The radiofrequency electrodes or MWA antennas were implanted in the centers of the artificial cystic lesions...
January 11, 2018: Academic Radiology
https://www.readbyqxmd.com/read/29325292/-therapeutic-effect-of-transcatheter-arterial-chemoembolization-combined-with-ultrasound-guided-microwave-ablation-for-treatment-of-liver-cancer-in-special-sites
#4
A Liu, W Xu, H Xu, Y Wang, Y M Gu
Objective: To investigate the efficacy and clinical value of transcatheter arterial chemoembolization (TACE) combined with ultrasound-guided microwave ablation for the treatment of liver cancer in special sites. Methods: The patients with liver cancer in special sites (the liver cancer was adjacent to the gallbladder, dome of diaphragm, gastrointestinal tract, heart, great vessels, and portal vein, with the shortest distance from the tumor to the organ/lumen < 0.5 cm ) were enrolled as treatment group, and the patients with primary liver cancer in normal sites treated in our hospital during the same period were randomly enrolled as control group...
December 20, 2017: Zhonghua Gan Zang Bing za Zhi, Zhonghua Ganzangbing Zazhi, Chinese Journal of Hepatology
https://www.readbyqxmd.com/read/29317376/a-comparison-between-915-mhz-and-2450-mhz-microwave-ablation-systems-for-the-treatment-of-small-diameter-lung-metastases
#5
Thomas J Vogl, Andrei Roman, Nour-Eldin A Nour-Eldin, Wolfgang Hohenforst-Schmidt, Iliana Bednarova, Benjamin Kaltenbach
PURPOSE: We aimed to retrospectively compare the local tumor control rates between low frequency (LF) and high frequency (HF) microwave ablation devices in the treatment of <3 cm lung metastases. METHODS: A total of 36 patients (55 tumors) were treated with the LF system (915 MHz) and 30 patients (39 tumors) were treated with the HF system (2450 MHz) between January 2011 and March 2016. Computed tomography (CT) scans performed prior to and 24 hours after the ablation were used to measure the size of the ablation zone and to calculate the ablation margin...
January 2018: Diagnostic and Interventional Radiology: Official Journal of the Turkish Society of Radiology
https://www.readbyqxmd.com/read/29317375/does-doxorubicin-survive-thermal-ablation-results-of-an-ex-vivo-bench-top-study
#6
Joseph D Morrison, Collin K Schlager, Amanda E Lee, Richard B van Breemen, Ron C Gaba
PURPOSE: We aimed to test the hypothesis that doxorubicin (DOX) survives thermal ablative heating in an ex vivo model of combined transarterial chemoembolization (TACE) and thermal ablation. METHODS: Fresh porcine psoas major muscle (3 samples, 15×10×3 cm) was submerged in aqueous DOX solution (60 µg/mL, 0.1 M) for 24 hours to passively saturate tissue. DOX-infused tissue was then dried and treated with microwave ablation (MWA) using a 2.45 GHz antenna at 65 W for 2, 5, and 10 minutes...
January 2018: Diagnostic and Interventional Radiology: Official Journal of the Turkish Society of Radiology
https://www.readbyqxmd.com/read/29312649/microwave-ablation-versus-radiofrequency-ablation-for-the-treatment-of-pulmonary-tumors
#7
Feng Shi, Guangxiao Li, Zejian Zhou, Rongde Xu, Weike Li, Wenhang Zhuang, Zide Chen, Xiaoming Chen
To retrospectively compare the efficacy and safety of radiofrequency ablation (RFA) and microwave ablation (MWA) in the treatment of pulmonary tumors, a total of 75 patients with lung tumor who underwent thermal ablation therapy in Guangdong General Hospital into the study from March 2007 to December 2014 were enrolled. Of the patients, 43 received radiofrequency ablation and 32 received microwaves ablation. The response rates, overall survival (OS), and complications rates between the RFA group and MWA group were compared...
December 12, 2017: Oncotarget
https://www.readbyqxmd.com/read/29303914/current-opinion-in-urology-2017-focal-therapy-of-small-renal-lesions
#8
Brett A Johnson, Jeffrey A Cadeddu
PURPOSE OF REVIEW: With the increasing incidence of small renal masses (SRMs), ablative technologies are becoming more commonly utilized. With any nascent treatment modality, outcomes literature needs to be constantly re-evaluated. The purpose of this review is to revisit the most updated literature regarding the safety and efficacy of ablative treatments of renal lesions. RECENT FINDINGS: Recent literature demonstrates that small renal tumor ablation is safe and effective...
January 4, 2018: Current Opinion in Urology
https://www.readbyqxmd.com/read/29303011/sonographic-measurement-of-thyroid-nodule-changes-after-microwave-ablation-relationship-between-multiple-parameters
#9
Ying Wei, Linxue Qian, Ji-Bin Liu, Yujiang Liu
OBJECTIVE: Microwave ablation (MWA) is an effective technique for the treatment of benign thyroid nodules. The aim of this study was to investigate whether it is necessary to study changes in variables other than the volume reduction between follow-up intervals. This study also introduced the index R (Ssurface/V) to explore whether it could reflect features of shape between follow-up intervals. MATERIALS AND METHODS: A total of 236 complex benign thyroid nodules in 230 patients who underwent MWA in our department from October 2013 to February 2017 were included...
January 5, 2018: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/29299366/bridging-therapy-effectiveness-in-the-treatment-of-hepatocellular-carcinoma-prior-to-orthotopic-liver-transplantation
#10
Maria M Rubinstein, Andreas Kaubisch, Milan Kinkhabwala, John Reinus, Qiang Liu, Jennifer W Chuy
Background: Orthotopic liver transplantation (OLT) is the most effective treatment for hepatocellular carcinoma (HCC) in patients with underlying cirrhosis and portal hypertension. Availability of OLT is limited by donor-organ shortages, which increase patient waiting time until OLT. A variety of bridging therapies (BT) have been used to halt tumor progression in patients on the OLT waiting list. Despite complete radiologic responses following BT, viable tumor is often present in explants...
December 2017: Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/29282555/green-adeptness-in-the-synthesis-and-stabilization-of-copper-nanoparticles-catalytic-antibacterial-cytotoxicity-and-antioxidant-activities
#11
REVIEW
Muhammad Imran Din, Farhan Arshad, Zaib Hussain, Maria Mukhtar
Copper nanoparticles (CuNPs) are of great interest due to their extraordinary properties such as high surface-to-volume ratio, high yield strength, ductility, hardness, flexibility, and rigidity. CuNPs show catalytic, antibacterial, antioxidant, and antifungal activities along with cytotoxicity and anticancer properties in many different applications. Many physical and chemical methods have been used to synthesize nanoparticles including laser ablation, microwave-assisted process, sol-gel, co-precipitation, pulsed wire discharge, vacuum vapor deposition, high-energy irradiation, lithography, mechanical milling, photochemical reduction, electrochemistry, electrospray synthesis, hydrothermal reaction, microemulsion, and chemical reduction...
December 28, 2017: Nanoscale Research Letters
https://www.readbyqxmd.com/read/29278340/microwave-ablation-of-pancreatic-tumors
#12
Thomas J Vogl, Bita Panahi, Moritz H Albrecht, Nagy Naguib Naeem Naguib, Nour-Eldin A Nour-Eldin, Tatjana Gruber-Rouh, Zachary M Thompson, Lajos M Basten
OBJECTIVES: To evaluate the clinical performance of percutaneous microwave ablation (MWA) for treatment of locally-advanced-pancreatic-cancer (LAPC). MATERIAL AND METHODS: Twenty-two MWA sessions (August 2015-March 2017) in 20 patients with primary pancreatic cancer (13 men, 7 women, mean-age: 59.9 ± 8.6 years, range: 46-73 years), who had given informed consent, were retrospectively evaluated. All procedures were performed percutaneously under CT-guidance using the same high-frequency (2...
December 26, 2017: Minimally Invasive Therapy & Allied Technologies: MITAT
https://www.readbyqxmd.com/read/29273176/local-recurrence-after-microwave-thermosphere-ablation-of-malignant-liver-tumors-results-of-a-surgical-series
#13
Hideo Takahashi, Bora Kahramangil, Eren Berber
BACKGROUND: Microwave thermosphere ablation is a new treatment modality that creates spherical ablation zones using a single antenna. This study aims to analyze local recurrence associated with this new treatment modality in patients with malignant liver tumors. METHODS: This is a prospective clinical study of patients who underwent microwave thermosphere ablation of malignant liver tumors between September 2014 and March 2017. Clinical, operative, and oncologic parameters were analyzed using Kaplan-Meier survival and Cox proportional hazards model...
December 19, 2017: Surgery
https://www.readbyqxmd.com/read/29246023/does-primary-tumor-location-impact-the-prognosis-of-colorectal-liver-metastases-patients-after-microwave-ablation-lessons-from-10-years-experience
#14
REVIEW
Fubo Zhou, Xiaoling Yu, Ping Liang, Zhiyu Han, Zhigang Cheng, Jie Yu, Fangyi Liu, Yi Hu
Thermal ablation has been considered as an alternative for local curative intent in patients with unresectable colorectal liver metastases. The influence of primary tumor location on the prognosis of colorectal liver metastases patients who have undergone microwave ablation has yet to be determined. We reviewed 295 patients who underwent microwave ablation for colorectal liver metastases at our institution between March 2006 and March 2016. Univariate and multivariate analyses were performed to identify predictors of overall and progression-free survival...
November 21, 2017: Oncotarget
https://www.readbyqxmd.com/read/29237896/microwave-ablation-results-with-three-different-diameters-of-antennas-in-ex-vivo-bovine-and-in-vivo-porcine-liver
#15
Ze Song, Han Qi, Hao Zhang, Lin Xie, Fei Cao, Weijun Fan, Chao Wan
PURPOSE: To evaluate the ablation ranges and temperature rising rates of three microwave antenna with different diameters in vitro bovine and in vivo porcine livers. MATERIALS AND METHODS: In vitro and in vivo study, microwave ablations (MWA) were induced at a power output of 70 W for 5, 8, and 10 min; a total of 54 and 36 ablations were performed, respectively. Temperature measurements were performed in the 70 W/10 min group with 3 different microwave antennas...
2017: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/29231067/in-vitro-artifact-assessment-of-an-mr-compatible-microwave-antenna-device-for-percutaneous-tumor-ablation-with-fluoroscopic-mri-sequences
#16
David-Emanuel Kessler, Jakob Weiss, Hansjörg Rempp, Philippe L Pereira, Konstantin Nikolaou, Stephan Clasen, Rüdiger Hoffmann
OBJECTIVE: To evaluate artifact configuration and diameters of a magnetic resonance (MR) compatible microwave (MW) applicator using near-realtime MR-fluoroscopic sequences for percutaneous tumor ablation procedures. MATERIAL AND METHODS: Two MW applicators (14 G and 16 G) were tested in an ex-vivo phantom at 1.5 T with two 3 D fluoroscopic sequences: T1-weighted spoiled Gradient Echo (GRE) and T1/T2-weighted Steady State Free Precession (SSFP) sequence. Applicator orientation to main magnetic field (B0), slice orientation and phase encoding direction (PED) were systematically varied...
December 12, 2017: Minimally Invasive Therapy & Allied Technologies: MITAT
https://www.readbyqxmd.com/read/29225619/clinical-application-of-ct-guided-percutaneous-microwave-ablation-for-the-treatment-of-lung-metastasis-from-colorectal-cancer
#17
Lin Li, Ketong Wu, Haiyang Lai, Bo Zhang
Objective: The aim of our research is to explore the clinical efficacy and safety of CT-guided percutaneous microwave ablation (MWA) for the treatment of lung metastasis from colorectal cancer. Materials and Methods: CT-guided percutaneous MWA was performed in 22 patients (male 14, female 8, mean age: 56.05 ± 12.32 years) with a total of 36 lung metastatic lesions from colorectal cancer between February 2014 and May 2017. Clinical data were retrospectively analyzed with respect to the efficacy, safety, and outcome...
2017: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/29215883/the-conformational-map-of-phenolic-acids
#18
Vanessa Cortijo, Elena R Alonso, Santiago Mata, Jose Luis Alonso
The benefits of vaporization by laser ablation and the high resolution and sensitivity attained by the chirped pulse Fourier transform microwave spectroscopy CP-FTMW have provided the first conformational map of the simplest phenolic acids of trans-cinnamic and p-coumaric. Two conformers of trans-cinnamic acid and four conformers of trans-p-coumaric acid have been characterized under the isolation conditions of a supersonic expansion. The spectroscopic constants derived from the analysis of the rotational spectra compared with those predicted theoretically provide an unmatched means to achieve an unambiguous identification of the observed species...
December 7, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/29204695/percutaneous-image-guided-ablation-in-the-treatment-of-osseous-metastases-from-non-small-cell-lung-cancer
#19
Yuntong Ma, Adam N Wallace, Saiama N Waqar, Daniel Morgensztern, Thomas P Madaelil, Anderanik Tomasian, Jack W Jennings
INTRODUCTION: Percutaneous image-guided ablation is an emerging minimally invasive therapy for patients with metastatic bone disease for whom radiation therapy is ineffective or contraindicated. The purpose of this study was to examine the safety and efficacy of percutaneous ablation in achieving pain palliation and local tumor control of osseous metastases from non-small cell lung cancer (NSCLC). METHODS: A retrospective review was performed of 76 musculoskeletal metastases in 45 patients treated with percutaneous ablation...
December 4, 2017: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/29203394/percutaneous-microwave-versus-radiofrequency-ablation-of-colorectal-liver%C3%A2-metastases-ablation-with-clear-margins-a0-provides-the-best-local-tumor%C3%A2-control
#20
Waleed Shady, Elena N Petre, Kinh Gian Do, Mithat Gonen, Hooman Yarmohammadi, Karen T Brown, Nancy E Kemeny, Michael D'Angelica, Peter T Kingham, Stephen B Solomon, Constantinos T Sofocleous
PURPOSE: To identify and compare predictors of local tumor progression (LTP)-free survival (LTPFS) after radiofrequency (RF) ablation and microwave (MW) ablation of colorectal liver metastases (CLMs). MATERIALS AND METHODS: This is a retrospective review of CLMs ablated from November 2009 to April 2015 (110 patients). Margins were measured on contrast-enhanced computed tomography (CT) 6 weeks after ablation. Clinical and technical predictors of LTPFS were assessed using a competing risk model adjusted for clustering...
December 2, 2017: Journal of Vascular and Interventional Radiology: JVIR
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