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https://www.readbyqxmd.com/read/28927661/local-control-and-survival-after-image-guided-percutaneous-ablation-of%C3%A2-adrenal%C3%A2-metastases
#1
Nathan E Frenk, Dania Daye, Kemal Tuncali, Ronald S Arellano, Paul B Shyn, Stuart G Silverman, Florian J Fintelmann, Raul N Uppot
PURPOSE: To evaluate local control and survival after image-guided ablation of adrenal gland metastases. MATERIALS AND METHODS: Image-guided ablations of adrenal metastases measuring < 5 cm performed at 2 academic medical centers between July 2002 and June 2016 were analyzed. There were 51 procedures performed on 46 tumors (mean diameter 2.8 cm ± 1.1; range, 0.7-4.9 cm) in 38 patients (mean age 66 y; range, 41-80 y) with renal cell carcinoma (n = 17 patients; 45%), non-small cell lung cancer (n = 10 patients; 26%), and other primary malignancies (n = 11 patients; 29%)...
September 16, 2017: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/28922946/temperature-simulation-of-microwave-ablation-based-on-improved-specific-absorption-rate-method-compared-to-phantom-measurements
#2
Hongjian Gao, Shuicai Wu, Xiaoru Wang, Rui Hu, Zhuhuang Zhou, Xuecong Sun
PURPOSE: To propose an improved specific absorption rate (SAR) computation method by incorporating a thermal conductivity item, develop mathematical simulation models based on the SAR, and enhance the accuracy of temperature simulation for 2450-MHz microwave fields. MATERIALS AND METHODS: Experimental data of 2450-MHz microwave antenna were obtained with a phantom and then new SAR equations were calculated according to Pennes bio-heat transfer equation. Next, the SAR equations were regarded as heating sources and SAR-derived temperature changes were simulated numerically; Finally, temperature measurement results were compared with simulation data to validate the accuracy of the new SAR method...
September 18, 2017: Computer Assisted Surgery (Abingdon, England)
https://www.readbyqxmd.com/read/28917643/a-novel-3-dimensional-electromagnetic-guidance-system-increases-intraoperative-microwave-antenna-placement-accuracy
#3
Amit V Sastry, Jacob H Swet, Keith J Murphy, Erin H Baker, Dionisios Vrochides, John B Martinie, Iain H McKillop, David A Iannitti
BACKGROUND: Failure to locate lesions and accurately place microwave antennas can lead to incomplete tumor ablation. The Emprint™ SX Ablation Platform employs real-time 3D-electromagnetic spatial antenna tracking to generate intraoperative laparoscopic antenna guidance. We sought to determine whether Emprint™ SX affected time/accuracy of antenna-placement in a laparoscopic training model. METHODS: Targets (7-10 mm) were set in agar within a laparoscopic training device...
September 13, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28915624/microwave-ablation-combined-with-egfr-tkis-versus-only-egfr-tkis-in-advanced-nsclc-patients-with-egfr-sensitive-mutations
#4
Zhigang Wei, Xin Ye, Xia Yang, Aimin Zheng, Guanghui Huang, Wenhong Li, Jiao Wang, Xiaoying Han, Min Meng, Yang Ni
We conducted this retrospective study to investigate whether microwave ablation (MWA) of primary tumor sites plus epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) could improve survival in advanced non small cell lung cancer (NSCLC) with EGFR mutations. MWA was conducted at the primary tumor sites, followed by EGFR-TKIs in the MWA plus EGFR-TKIs group. EGFR-TKIs were administered until disease progression or intolerable toxicity. The primary endpoint was progression-free survival (PFS); secondary endpoints were overall survival (OS) and objective response rate (ORR)...
August 22, 2017: Oncotarget
https://www.readbyqxmd.com/read/28913628/delayed-bronchocutaneous-fistula-without-pneumothorax-following-a-microwave-ablation-of-a-recurrent-pulmonary-metastasis
#5
Arnaud Thivolet, Badis Menassel, Gérard Chatté, Mayeul Tabutin, Amine Bouhamama, Frank Pilleul, Charles Mastier
Percutaneous tumor ablations are rather safe and effective treatments in selected patients for non-operable non-small cell lung carcinomas or lung metastases. However, there are major complications such as bronchopleural or bronchocutaneous fistula, which it is important to know in order to manage them safely. We describe in this report a case of bronchocutaneous fistula without pneumothorax following a microwave ablation of a recurrent pulmonary metastasis and its management.
September 14, 2017: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/28901314/repeated-percutaneous-microwave-ablation-for-local-recurrence-of-inoperable-stage-i-nonsmall-cell-lung-cancer
#6
Xia Yang, Xin Ye, Guanghui Huang, Xiaoying Han, Jiao Wang, Wenhong Li, Zhigang Wei, Min Meng
BACKGROUND: The safety and effectiveness of repeated computed tomography-guided percutaneous microwave ablation (MWA) in the management of local recurrence (LR) in patients with medically inoperable Stage I nonsmall cell lung cancer (NSCLC) were retrospectively evaluated. MATERIALS AND METHODS: From February 2008 to August 2014, 104 patients with medically inoperable Stage I NSCLC received MWA. Patients with LR were given repeat MWA. The clinical outcomes and complications of repeat MWA for LR were evaluated...
2017: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/28894936/thermal-ablation-of-thyroid-nodules-are-radiofrequency-ablation-microwave-ablation-and-high-intensity-focused-ultrasound-equally-safe-and-effective-methods
#7
Yücel Korkusuz, Daniel Gröner, Natascha Raczynski, Oleg Relin, Yasmina Kingeter, Frank Grünwald, Christian Happel
OBJECTIVES: This study compares volume reduction of benign thyroid nodules three months after Radiofrequency Ablation (RFA), Microwave Ablation (MWA) or High Intensity Focused Ultrasound (HIFU) to evaluate which of these methods is the most effective and safe alternative to thyroidectomy or radioiodine therapy. MATERIAL AND METHODS: Ninety-four patients (39 male, 55 female) with a total of 118 benign, symptomatic thyroid nodules were divided into three subgroups...
September 11, 2017: European Radiology
https://www.readbyqxmd.com/read/28881688/the-clinical-utility-and-outcomes-of-microwave-ablation-for-colorectal-cancer-liver-metastases
#8
Pengyuan Song, Lijun Sheng, Yahong Sun, Yuji An, Ya Guo, Yafei Zhang
In recent years, the microwave ablation (MWA) has been reported to play an important role in the treatment of patients with colorectal liver metastases (CRLM). In this work, 62 cases of patients who received MWA for liver metastases from colon or rectal cancer between Jan 2012 and Jan 2014 were enrolled in this trial. 28 underwent MWA, and 34 were treated with liver resection as control. Perioperative and 60 months of follow-up data were collected to analyze potential adverse effects, concurrent conditions and survival status...
August 1, 2017: Oncotarget
https://www.readbyqxmd.com/read/28877612/the-role-of-mri-in-the-early-evaluation-of-lung-microwave-ablation
#9
Andrei Roman, Benjamin Kaltenbach, Tatjana Gruber-Rouh, Nagy N Naguib, Thomas J Vogl, Nour-Eldin A Nour-Eldin
PURPOSE: To retrospectively investigate the role of a contrast enhanced MRI (ceMRI) performed 24 hours after a microwave ablation (MWA) of the lung, in predicting local tumor progression (LTP) and detecting complications compared to an unenhanced CT Material and methods: Forty-nine patients that underwent MWA of 77 lung metastases between 2008 and 2015 were included. All patients received an unenhanced chest CT and a ceMRI (including T2 and ceT1) 24h after MWA. The conspicuities of the peripheral rim and of the ablated tumor were scored using 1-3 scales and compared between examinations...
September 6, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/28875198/the-role-of-amino-acid-side-chains-in-stabilizing-dipeptides-the-laser-ablation-fourier-transform-microwave-spectrum-of-ac-val-nh2
#10
I León, E R Alonso, S Mata, C Cabezas, M A Rodríguez, J-U Grabow, J L Alonso
The steric effects imposed by the isopropyl group of valine in the conformational stabilization of the capped dipeptide N-acetyl-l-valinamide (Ac-Val-NH2) have been studied by laser ablation molecular beam Fourier transform microwave (LA-MB-FTMW) spectroscopy. The rotational and quadrupole coupling constants of the two (14)N nuclei determined in this work show that this dipeptide exists as a mixture of C7 and C5 conformers in the supersonic expansion. The conformers are stabilized by a C[double bond, length as m-dash]OH-N intramolecular hydrogen bond closing a seven- or a five-membered ring, respectively...
September 20, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28869200/irreversible-electroporation-and-thermal-ablation-of-tumors-in-the-liver-lung-kidney-and-bone-what-are-the-differences
#11
REVIEW
L G P H Vroomen, E N Petre, F H Cornelis, S B Solomon, G Srimathveeravalli
Focal treatment with radiofrequency, microwave and cryoablation has been increasingly used for the treatment of tumors in patients who cannot undergo surgical resection and in select patients with early stage or oligometastatic disease. Each of these ablation modalities has a unique working principle and biophysics underlying the ablative effect, which largely determines the clinical indication for its application. Irreversible electroporation, a relatively new ablation technique with a predominantly nonthermal cell killing mechanism has emerged as an alternative treatment technique for tumors that are contraindicated for thermal ablation because of safety or efficacy considerations...
September 2017: Diagnostic and Interventional Imaging
https://www.readbyqxmd.com/read/28866952/optical-flow-and-image-segmentation-analysis-for-noninvasive-precise-mapping-of-microwave-thermal-ablation-in-x-ray-ct-scans-ex-vivo-study
#12
Omri Ziv, S Nahum Goldberg, Yitzhak Nissenbaum, Jacob Sosna, Noam Weiss, Haim Azhari
PURPOSE: To develop image processing algorithms for noninvasive mapping of microwave thermal ablation using X-ray CT. METHODS: Ten specimens of bovine liver were subjected to microwave ablation (20-80W, 8 minutes) while scanned by X-ray CT at 5 seconds intervals. Specimens were cut and manually traced by two observers. Two algorithms were developed and implemented to map the ablation zone. The first algorithm utilizes images segmentation of Hounsfield units changes (ISHU)...
September 3, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/28857194/local-incompressible-registration-for-liver-ablation-surgery-assessment
#13
Tianyu Fu, Qin Li, Dingkun Liu, Danni Ai, Hong Song, Ping Liang, Yongtian Wang, Jian Yang
PURPOSE: In liver microwave ablation (MWA) surgery, the ablation area covers the tumor to generate tissue necrosis and treat the cancer. As the liver deforms during the operation, deviation between the target area determined during pre-operative planning and the resultant ablation area is inevitable. Therefore, an accurate assessment of tumor coverage is crucial for treatment. Through registration between the pre- and post-operative livers, the ablation area is warped on the pre-operative liver for the computation of tumor coverage...
August 30, 2017: Medical Physics
https://www.readbyqxmd.com/read/28855431/us-guided-percutaneous-microwave-ablation-for-the-treatment-of-benign-thyroid-nodules
#14
Wenjun Wu, Xiaohua Gong, Qi Zhou, Xiong Chen, Xiaojun Chen, Bimin Shi
The aim of this study was to define the effectiveness and safety of ultrasound(US)-guided percutaneous microwave ablation(MWA) for benign thyroid nodules with one session treatment. A total 121 benign thyroid nodules in 100 euthyroid patients underwent MWA in one medical center between August 2014 and December 2015. MWA was performed with an internally cooled antenna under local anesthesia. The volume of the nodule, cosmetic score and symptom score were compared before and after the procedure. The volume reduction rate(VRR) was also evaluated...
August 29, 2017: Endocrine Journal
https://www.readbyqxmd.com/read/28844613/percutaneous-thermal-ablation-of-lung-tumors-radiofrequency-microwave-and-cryotherapy-where-are-we-going
#15
J Palussière, V Catena, X Buy
Main indications of percutaneous pulmonary thermal ablation are early stage non-small cell lung carcinoma (NSCLC) for patients who are not amenable to surgery and slow-evolving localized metastatic disease, either spontaneous or following a general treatment. Radiofrequency ablation (RFA) is the most evaluated technique. This technique offers a local control rate ranging between 80 and 90% for tumors <3cm in diameter. Other more recently used ablation techniques such as microwaves and cryotherapy could overcome some limitations of RFA...
September 2017: Diagnostic and Interventional Imaging
https://www.readbyqxmd.com/read/28842651/us-guided-percutaneous-radiofrequency-versus-microwave-ablation-for-benign-thyroid-nodules-a-prospective-multicenter-study
#16
Zhigang Cheng, Ying Che, Songyuan Yu, Shurong Wang, Dengke Teng, Huixiong Xu, Jianwei Li, Desheng Sun, Zhiyu Han, Ping Liang
Compared with microwave ablation (MWA), percutaneous radiofrequency ablation (RFA) and laser ablation (LA) have been recommended as minimally invasive treatments for patients with symptomatic benign thyroid nodules (BTNs) because of the large number of clinical applications. This prospective multicenter study sought to evaluate the clinical outcomes of RFA and MWA for BTNs. In eight participating institutions, the total number of 1252 patients treated by RFA and MWA were 649 ones with 687 BTNs and 603 ones with 664 BTNs, respectively...
August 25, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28842005/new-procedure-of-quantitative-mapping-of-ti-and-al-released-from-dental-implant-and-mg-ca-fe-zn-cu-mn-as-physiological-elements-in-oral-mucosa-by-la-icp-ms
#17
Adam Sajnóg, Anetta Hanć, Ryszard Koczorowski, Danuta Barałkiewicz
A new procedure for determination of elements derived from titanium implants and physiological elements in soft tissues by laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) is presented. The analytical procedure was developed which involved preparation of in-house matrix matched solid standards with analyte addition based on certified reference material (CRM) MODAS-4 Cormorant Tissue. Addition of gelatin, serving as a binding agent, essentially improved physical properties of standards...
December 1, 2017: Talanta
https://www.readbyqxmd.com/read/28834968/microwave-ablation-mwa-basics-technique-and-results-in-primary-and-metastatic-liver-neoplasms-review-article
#18
Thomas J Vogl, Nour-Eldin A Nour-Eldin, Renate Maria Hammerstingl, Bita Panahi, Nagy N N Naguib
Purpose The locoregional interventional oncological treatment approach is an accepted modality for liver neoplasms, especially for hepatocellular carcinoma (HCC) and oligonodular liver metastases. Materials and Methods The main aim of ablation therapies like microwave ablation (MWA) is to eradicate all malignant cells in a minimally invasive technique under imaging guidance while preserving the healthy tissue with a sufficient safety margin (at least 5 mm) surrounding the ablated lesion. Results Ablation therapy can be performed via a percutaneous, laparoscopic or intraoperative approach under ultrasound, MRI or CT guidance for adequate localization and monitoring of the ablation process...
August 23, 2017: RöFo: Fortschritte Auf Dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
https://www.readbyqxmd.com/read/28828899/computed-tomography-guided-percutaneous-microwave-ablation-of-hepatocellular-carcinoma-in-challenging-locations-safety-and-efficacy-of-high-power-microwave-platforms
#19
D K Filippiadis, S Spiliopoulos, C Konstantos, L Reppas, A Kelekis, E Brountzos, N Kelekis
OBJECTIVES: To evaluate the clinical efficacy/safety of CT-guided percutaneous microwave ablation for HCC in challenging locations using high-power microwave platforms. MATERIALS AND METHODS: A retrospective review was conducted in 26 patients with 36 HCC tumorss in challenging locations (hepatic dome, subcapsular, close to the heart/diaphragm/hepatic hilum, exophytic) undergoing CT-guided percutaneous microwave ablation in a single centre since January 2011. Two different microwave platforms were used both operating at 2...
August 22, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/28814882/the-effect-of-lipiodol-deposition-in-hcc-after-tace-on-the-necrosis-range-of-pmct
#20
HongLiang Sun, JiaYan Ni, XiongYing Jiang, Dong Chen, YaoTing Chen, LinFeng Xu
OBJECTIVE: To study the impact of lipiodol deposition in the lesion of hepatocellular carcinoma (HCC) after transarterial chemoembolization (TACE) on the necrosis area of percutaneous microwave coagulation therapy (PMCT). MATERIALS AND METHODS: A total of 44 patients with HCC with 56 nodules, with a size ranging from 1.5 to 3.5 cm, was selected in our study. About 23 patients (26 nodules) underwent PMCT treatment only as Group A and 21 patients (30 nodules) were treated by PMCT-combined TACE as Group B...
2017: OncoTargets and Therapy
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