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https://www.readbyqxmd.com/read/28538887/ductal-eccrine-carcinoma-of-the-axilla-a-diagnostic-pitfall
#1
Maria Helena Toda Sanches de Brito, Cecília Silva Nunes de Moura Dionísio, Joana Cintia Monteiro Ferreira, Maria Joaninha Madalena de Palma Mendonça da Costa Rosa, Fernando Petrucci Bernardo E Cunha, Maria Manuela Antunes Pecegueiro da Silva Garcia
Ductal eccrine carcinoma (DEC) is a rare sweat gland carcinoma with ductular differentiation. Clinically, it is characterized by a slowly growing, hardened plaque or nodule predominantly located on the head and neck. Histologically, DEC shares similar features to invasive breast carcinoma, thus causing great diagnostic challenges. We report a 69-year-old woman who presented with a hardened plaque on the axilla. A skin biopsy was performed and metastatic invasive breast carcinoma could not be ruled out. Complete excision and further workup were subsequently conducted, leading to the diagnosis of estrogen receptor positive DEC with associated axillary lymph node metastases...
March 2017: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/28529419/comparative-study-of-efficacy-and-safety-of-botulinum-toxin-a-injections-and-subcutaneous-curettage-in-the-treatment-of-axillary-hyperhidrosis
#2
Leelavathy Budamakuntla, Eswari Loganathan, Anju George, B N Revanth, V Sankeerth, Sacchidananda Aradhya Sarvjnamurthy
BACKGROUND: Primary focal axillary hyperhidrosis is a chronic distressing disorder affecting both the sexes. When the condition is refractory to conservative management, we should go for more promising therapies like intradermal botulinum toxin A (BtxA) injections in the axilla, and surgical therapies like subcutaneous curettage of sweat glands. AIMS AND OBJECTIVES: The aim of this study is to compare the efficacy, safety and duration of action of intradermal BtxA injections in one axilla and subcutaneous curettage of sweat glands in the other axilla of the same patient with axillary hyperhidrosis...
January 2017: Journal of Cutaneous and Aesthetic Surgery
https://www.readbyqxmd.com/read/28528731/-hidradenocarcinoma-of-the-heel-associated-with-inguinal-metastases
#3
W Labbardi, F Hali, F Marnissi, B Cribier, S Chiheb
BACKGROUND: Hidradenocarcinoma is a rare malignant tumour involving the sweat glands. It classically arises de novo, only rarely resulting from pre-existing hidradenoma. The literature contains few reports of lymph node metastasis in this tumour. We report a case of a patient with hidradenocarcinoma of the heel associated with inguinal node metastases. PATIENTS AND METHODS: We report the case of a 64-year-old patient with a history of chronic smoking, who in the last two years developed a painless nodule in his right heel, with no prior injury, and which gradually increased in size to become an ulcerated tumour...
May 18, 2017: Annales de Dermatologie et de Vénéréologie
https://www.readbyqxmd.com/read/28522768/a-model-for-in-vivo-analysis-of-sudomotor-sympathetic-c-fiber-activation-and-human-sweat-gland-output
#4
Gary W Mack
Quantitative assessment of small fiber peripheral neuropathy often involves an evaluation of the interaction between the C-fiber sudomotor nerve and local sweat rate (SR). Typically, some sort of quantitative sudomotor axon reflex test (QSART) is performed to aid in diagnosing small fiber dysfunction. The currently used QSART demonstrates only moderate test-retest reliability and therefore limits its usefulness in tracking small fiber dysfunction. A new experimental model to examine small C-fiber function in the skin using intradermal electrical stimulation and simultaneous monitoring of SR is proposed...
May 18, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28516981/botulinum-toxin-therapy-functional-silencing-of-salivary-disorders
#5
A Lovato, D A Restivo, G Ottaviano, G Marioni, R Marchese-Ragona
Botulinum toxin (BTX) is a neurotoxic protein produced by Clostridium botulinum, an anaerobic bacterium. BTX therapy is a safe and effective treatment when used for functional silencing of the salivary glands in disorders such as sialoceles and salivary fistulae that may have a post-traumatic or post-operative origin. BTX injections can be considered in sialoceles and salivary fistulae after the failure of or together with conservative treatments (e.g. antibiotics, pressure dressings, or serial aspirations)...
April 2017: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/28510329/isolation-of-stem-cells-and-progenitors-from-mouse-epidermis
#6
Lana Kostic, Egor Sedov, Despina Soteriou, Yahav Yosefzon, Yaron Fuchs
The epidermis consists of several distinct compartments including the interfollicular epidermis (IFE), sweat glands, sebaceous glands (SGs), and the hair follicle (HF). While the IFE and SGs are in a constant state of self-renewal, the HF cycles between phases of growth, destruction, and rest. The hair follicle stem cells (HFSCs) that fuel this perpetual cycle have been well described and are located in a niche termed the bulge. These bulge SCs express markers such as CD34 and Keratin 15 (K15), enabling the isolation of these cells...
May 16, 2017: Current Protocols in Stem Cell Biology
https://www.readbyqxmd.com/read/28506659/comparison-of-density-and-output-of-sweat-gland-in-tropical-africans-and-temperate-koreans
#7
JeongBeom Lee, YoungOh Shin
Modification of sweating could be due to changes in activated sweat gland density (ASGD) and/or activated sweat gland output (ASGO). The present study determined regional and inter-ethnic differences in ASGD and ASGO during passive heating between tropical natives (African, n=22) and temperate natives (Republic of Korean, n=25). Heat load was carried out by immersing the half body into a hot water bath for 30min. Tympanic temperature (Tty) and skin temperature (Ts) were measured. Mean body temperature (mTb) was calculated...
May 8, 2017: Autonomic Neuroscience: Basic & Clinical
https://www.readbyqxmd.com/read/28503344/adnexal-tumors-of-skin-an-experience-at-a-tertiary-care-center-at-delhi
#8
M Pujani, G B Madaan, Z S Jairajpuri, S Jetley, M J Hassan, S Khan
BACKGROUND: Adnexal skin tumors are a heterogeneous group of uncommon tumors usually misdiagnosed clinically due to a huge variety of types and their variants. Histopathology usually helps in establishing the diagnosis. AIMS: The study was undertaken to analyze the morphological, clinical, and histological features of adnexal tumors (ATs) of the skin at our center over a period of 4 years. SUBJECTS AND METHODS: retrospective study was conducted over a period of 4 years (April 2010-March 2014), comprising 25 ATs of skin diagnosed in the Department of Pathology, Hamdard Institute of Medical Sciences and Research, Jamia Hamdard, New Delhi...
September 2016: Annals of Medical and Health Sciences Research
https://www.readbyqxmd.com/read/28497640/polarizable-crystals-in-apocrine-sweat-gland-tumors-a-series-of-three-cases
#9
Gina Johnson, Jerad M Gardner, Sara C Shalin
Polarizable calcium oxalate (CaOx) crystals have been well documented in breast biopsies, generally associated with benign apocrine metaplasia. In contrast, polarizable crystals are only rarely reported in skin adnexal neoplasms. We report three different cases of sweat gland tumors with polarizable crystals morphologically suggestive of CaOx: 1 apocrine hidrocystoma and 2 tubular apocrine adenomas. The histologic features were examined in 3 cases. Clinical presentation summary included 2 males and 1 female, ages 53 to 74, with lesions located on the left cheek, inferior vertex scalp and the left eyebrow...
May 12, 2017: Journal of Cutaneous Pathology
https://www.readbyqxmd.com/read/28495496/aggressive-digital-papillary-adenocarcinoma-a-clinicopathological-study-of-19-cases
#10
Noëlle Weingertner, Anne Gressel, Maxime Battistella, Bernard Cribier
BACKGROUND: Aggressive digital papillary adenocarcinomas (ADPA) are malignant tumors of sweat glands having recurrence/metastatic potential. OBJECTIVE: We sought to describe the clinical/histopathological characteristics of a series of ADPA. METHODS: This is a retrospective case series of 19 ADPA. RESULTS: The tumors occurred in 17 men and 2 women (mean age: 47 years). They involved digits (15), big toe (3), and palm (1), and measured from 3 to 30 mm...
May 9, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28495444/comparing-the-rtog-eortc-and-lent-soma-scoring-systems-for-the-evaluation-of-late-skin-toxicity-after-125-i-seed-brachytherapy-for-parotid-gland-cancer
#11
Ming-Hui Mao, Zhien Feng, Hua Li, Li-Zheng Qin, Jian-Hua Li, Xin Huang, Ru-Dong Xing, Jie Zhang, Jian-Guo Zhang, Zheng-Xue Han
PURPOSE: The Radiation Therapy Oncology Group (RTOG) and Late Effects Normal Tissue Task Force-Subjective, Objective, Management and Analytic (LENT-SOMA) scoring systems were compared for grading late skin effects after iodine-125 seed brachytherapy in parotid gland cancer patients. METHODS AND MATERIALS: A total of 109 patients diagnosed with parotid gland carcinoma were treated postoperatively with iodine-125 seed brachytherapy at a dose of 100-120 Gy. After 6-24 months of followup, telangiectasia, skin pigmentation, atrophy, fibrosis, and ulceration were scored according to both RTOG and LENT-SOMA scale criteria...
May 8, 2017: Brachytherapy
https://www.readbyqxmd.com/read/28491080/corrigendum-making-plants-break-a-sweat-the-structure-function-and-evolution-of-plant-salt-glands
#12
Maheshi Dassanayake, John C Larkin
[This corrects the article on p. 406 in vol. 8, PMID: 28400779.].
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28490040/individualized-plastic-reconstruction-strategy-for-patients-with-ectodermal-dysplasia-syndrome
#13
Yikang Hou, Yunbo Jin, Xiaoxi Lin, Gang Chai, Yan Zhang, Zuoliang Qi
Ectodermal dysplasia syndrome is a hereditary disease of ectodermal origin. Appearances of nail dystrophy, alopecia or hypotrichosis, saddle nose deformity, and palmoplantar hyperkeratosis are usually associated with a lack of sweat glands as well as partial or complete absence of teeth. These manifestations are usually corrected only with oral rehabilitation by mounting dentures. In this study, plastic rehabilitation was developed to correct the special features of patients with ectodermal dysplasia. Four men and 1 woman with ectodermal dysplasia syndrome were treated...
June 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28465863/low-beta-adrenergic-sweat-responses-in-cystic-fibrosis-and-cystic-fibrosis-transmembrane-conductance-regulator-related-metabolic-syndrome-children
#14
Danieli Barino Salinas, Lucia Kang, Colleen Azen, Paul Quinton
β-adrenergically stimulated sweat secretion depends on the function of the cystic fibrosis transmembrane conductance regulator (CFTR) and discriminates between cystic fibrosis (CF) patients and healthy controls. Therefore, we sought to determine the feasibility, safety, and efficacy of assaying β-adrenergic sweating in children identified by CF newborn screening to help determine prognoses for individuals with CFTR-related metabolic syndrome (CRMS). Preschool age children with a positive newborn screening test for CF participated in this cross-sectional study...
March 1, 2017: Pediatric Allergy, Immunology, and Pulmonology
https://www.readbyqxmd.com/read/28463974/the-histological-characteristics-age-related-thickness-change-of-skin-and-expression-of-the-hsps-in-the-skin-during-hair-cycle-in-yak-bos-grunniens
#15
Xue Yang, Yan Cui, Jing Yue, Honghong He, Chuan Yu, Penggang Liu, Jun Liu, Xiandong Ren, Yun Meng
OBJECTIVE: This experiment was conducted to study the histological characteristics, age-related thickness changes, and expression of HSPs in the skin of yak. METHODS: A total of 20 yaks (10 males and 10 females) were used. Different regions of the normal skin of three different ages (newborn, half-year-old and adult) of yaks were harvested for histological study and thickness measurement. Biopsy samples were taken from the scapula regions of the skin from the same five approximately 1-year-old yaks during the hair cycle (telogen, anagen and catagen)...
2017: PloS One
https://www.readbyqxmd.com/read/28458869/an-unusual-cause-of-back-pain-a-case-of-large-nonfunctioning-retroperitoneal-paraganglioma-presented-as-a-large-cystic-lesion-a-case-report-and-review-of-literature
#16
Siu Yan Amy Kok, Chung Ying Leung, Ki Yau Chow
Pheochromocytoma arising from outside the adrenal glands is also called paraganglioma. When it occurs below the diaphragm, in the organ of Zuckerkandl or retroperitoneum, it is also called extra-adrenal pheochromocytoma. Paragangliomas are rare tumors which arise from neuroendocrine cells and extra-adrenal paragangliomas (EAPs) account for only 10-15% if all paragangliomas and may present incidentally as a symptomless mass. Typical triad of sweating, headache and fluctuating hypertension if not present makes preoperative diagnosis difficult...
April 2017: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/28447185/maximum-rate-of-sweat-ions-reabsorption-during-exercise-with-regional-differences-sex-and-exercise-training
#17
Tatsuro Amano, Megumi Hirose, Kana Konishi, Nicola Gerrett, Hiroyuki Ueda, Narihiko Kondo, Yoshimitsu Inoue
PURPOSE: It is recently reported that determining sweat rate (SR) threshold for increasing galvanic skin conductance (GSC) would represent a maximum rate of sweat ion reabsorption in sweat glands. We evaluate the maximum rate of sweat ion reabsorption over skin regions, sex, and long-term exercise training by using the threshold analysis in the present study. METHODS: Ten males (2 untrained, 4 sprinters, and 4 distance runners) and 12 females (5 untrained, 4 sprinters, and 3 distance runners) conducted graded cycling exercise for 45 min at low, middle, and high exercise intensities (heart rate 100-110, 120-130, and 140-150 beats/min, respectively) for 10, 15, and 20 min, respectively, at 30 °C and 50% relative humidity...
April 26, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28445202/adnexal-carcinomas-treated-with-mohs-micrographic-surgery-a-comprehensive-review
#18
Stanislav N Tolkachjov
BACKGROUND: Adnexal carcinomas (ACs) are rare cutaneous malignancies of sweat gland or pilosebaceous origin. Optimal treatment and metastatic potential of AC are poorly defined. Mohs micrographic surgery (MMS) has been increasingly used to treat AC. OBJECTIVE: To review selected primary cutaneous AC and their treatment outcomes with MMS. MATERIALS AND METHODS: Literature review using PubMed search for articles related to primary cutaneous ACs...
April 28, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28441468/histological-study-of-white-rhinoceros-integument
#19
Jeffrey H Plochocki, Saul Ruiz, José R Rodriguez-Sosa, Margaret I Hall
In this study, we report findings from a microscopic analysis of the white rhinoceros (Ceratotherium simum) integumentary ultrastructure. Skin samples from the cheek, shoulder, flank and rump were taken from a 46-year-old female southern white rhinoceros and examined using H&E and elastic histological stains. The epidermis was thickest in the flank (1.003 mm) followed by the rump, cheek and shoulder. The stratum corneum comprised more than half the epidermal thickness. Numerous melanin granules were found in the basal and spinosum layers...
2017: PloS One
https://www.readbyqxmd.com/read/28429515/a-device-to-measure-secretion-of-individual-sweat-glands-for-diagnosis-of-peripheral-neuropathy
#20
Adam J Loavenbruck, James S Hodges, Vincenzo Provitera, Maria Nolano, Gwen Wendelshafer-Crabb, William R Kennedy
INTRODUCTION: There is a need for quantitative, precise assessment of small fiber peripheral nerve function. We tested a customized camera device and protocol designed to quantify secretions of individual sweat glands (SGs). MATERIALS AND METHODS: Testing was performed on 178 healthy controls and 20 neuropathy subjects. Sweating was stimulated on a 2.25 cm(2) skin area by iontophoresis of pilocarpine. The camera imaged sweat from 50-400 sweat ducts. We calculated secretion rate of individual SGs, total sweat volume, and number of secreting SGs at four body sites...
April 21, 2017: Journal of the Peripheral Nervous System: JPNS
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