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Musculoskeletal medicine

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https://www.readbyqxmd.com/read/28534604/the-influence-of-expectations-on-improvements-in-pain-and-function-in-patients-with-neck-back-shoulder-complaints-a-cohort-study
#1
Sigrid Skatteboe, Cecilie Røe, Morten W Fagerland, Lars-Petter Granan
BACKGROUND: In musculoskeletal research, patients' expectations have recently received increased attention. However, few prospective studies have investigated these expectations or their prognostic significance and possible clinical value. AIM: To investigate the influence of patients' expectations on improvements in pain and functional status six months after an outpatient physical medicine assessment. DESIGN: A prospective cohort study. SETTING: Physical Medicine and Rehabilitation (PMR) outpatient clinic...
May 23, 2017: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/28527504/telehealth-in-physical-medicine-and-rehabilitation-a-narrative-review
#2
REVIEW
Adam S Tenforde, Jaye E Hefner, Jodi E Kodish-Wachs, Mary A Iaccarino, Sabrina Paganoni
Telehealth refers to health care interactions that leverage telecommunication devices to provide medical care outside the traditional face-to-face, in-person medical encounter. Technology advances and research have expanded use of telehealth in health care delivery. Physical medicine and rehabilitation providers may use telehealth to deliver care to populations with neurologic and musculoskeletal conditions, commonly treated in both acute care and outpatient settings. Patients with impaired mobility and those living in locations with reduced access to care may particularly benefit...
May 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/28509821/minimum-information-for-studies-evaluating-biologics-in-orthopaedics-mibo-platelet-rich-plasma-and-mesenchymal-stem-cells
#3
Iain R Murray, Andrew G Geeslin, Ewan B Goudie, Frank A Petrigliano, Robert F LaPrade
BACKGROUND: A comprehensive approach to the evaluation of biologic therapies for musculoskeletal conditions is required to guide appropriate future use. Clinical studies evaluating platelet-rich plasma (PRP) and mesenchymal stem cells (MSCs) are limited by inadequate reporting of scientific details critical to outcome. We developed minimum reporting requirements for clinical studies evaluating PRP and MSCs using Delphi consensus methods. METHODS: The need for consensus on the minimum reporting requirements for studies evaluating biologics was identified at the American Academy of Orthopaedic Surgeons/Orthopaedic Research Society (AAOS/ORS) Biologic Treatments for Orthopaedic Injuries Symposium in 2015 and the American Orthopaedic Society for Sports Medicine (AOSSM) Biologic Treatments for Sports Injuries II Think Tank in 2015...
May 17, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28503221/management-of-musculoskeletal-pain-in-retail-drug-outlets-within-a-nigerian-community-a-descriptive-study
#4
Samirah N Abdu-Aguye, Aishatu Shehu, Ubaidullah I Ahmad
OBJECTIVE: This work aimed to describe attitudes and practices of both community pharmacies and patent and proprietary medicine vendor (PPMV) outlets towards over-the-counter (OTC) analgesic use for musculoskeletal pain states within Zaria, Nigeria. METHODS: The study was carried out in 2 phases from May to August 2016. Phase one was a cross-sectional survey of 40 retail drug outlets (10 community pharmacies and 30 PPMVs). A simulated patient scenario of a young adult male complaining of acute onset back pain was used to collect data on the type and quality of analgesic recommended, duration of consultation, as well as nature of information provided during the drug dispensing process...
January 2017: Pharmacy Practice
https://www.readbyqxmd.com/read/28502741/high-metabolic-activity-of-tissue-nonspecific-alkaline-phosphatase-not-only-in-young-but-also-in-adult-bone-as-demonstrated-using-a-new-histochemical-detection-protocol
#5
I Piotr Maly, Elisabeth Eppler, Magdalena Müller-Gerbl
Tissue-nonspecific alkaline phosphatase (TNAP) is playing a key role in bone calcification, as has been demonstrated in different mammalian species including human and rodents. However, to investigate age-related changes during life history, histochemical demonstration of TNAP is severely hampered, particularly in the elderly, by technical difficulties associated with sectioning calcified tissue. Sufficient fixation must precede decalcification since poorly fixed bone tissue is exposed to the deleterious effects of decalcification reagents...
May 11, 2017: General and Comparative Endocrinology
https://www.readbyqxmd.com/read/28499245/anti-hyperalgesic-effect-of-lippia-grata-leaf-essential-oil-complexed-with-%C3%AE-cyclodextrin-in-a-chronic-musculoskeletal-pain-animal-model-complemented-with-a-molecular-docking-and-antioxidant-screening
#6
Pollyana S Siqueira-Lima, Renan G Brito, Heitor G Araújo-Filho, Priscila L Santos, Angélica Lucchesi, Adriano A S Araújo, Paula P Menezes, Luciana Scotti, Marcus T Scotti, Irwin R A Menezes, Henrique D M Coutinho, Gokhan Zengin, Abdurrahman Aktumsek, Angelo R Antoniolli, Lucindo J Quintans-Júnior, Jullyana S S Quintans
BACKGROUND: Due to its unclear pathophysiology, the pharmacological treatment of fibromyalgia is a challenge for researchers. Studies using medicinal plants, such as those from the genus Lippia, complexed with cyclodextrins (CDs) have shown innovative results. OBJECTIVE: The present research intended to evaluate the effect of an inclusion complex containing β-cyclodextrin (βCD) inclusion complex with Lippia grata (LG) essential oil in a chronic musculoskeletal pain model, its central activity and its possible interaction with neurotransmitters involved in pain...
May 9, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28494738/smart-and-controllable-raav-gene-delivery-carriers-in-progenitor-cells-for-human-musculoskeletal-regenerative-medicine-with-a-focus-on-the-articular-cartilage
#7
Ana Rey-Rico, Magali Cucchiarini
Cell therapy using mesenchymal stem cells (MSCs) is a powerful tool for the treatment of various diseases and injuries. Still, important limitations including the large amounts of cells required for application in vivo and the age-related decline in lifespan, proliferation, and potency may hinder the use of MSCs in patients. In this regard, gene therapy may offer strong approaches to optimize the use of MSCs for regenerative medicine. Diverse nonviral and viral gene vehicles have been manipulated to genetically modify MSCs, among which the highly effective and relatively safe recombinant adeno-associated viral (rAAV) vectors that emerged as the preferred gene delivery system to treat human disorders...
May 10, 2017: Current Gene Therapy
https://www.readbyqxmd.com/read/28486279/payor-reform-opportunities-for-spine-surgery-part-i-background-and-stimulus-for-bundled-payments
#8
Jason Scalise, David Jacofsky
Spine surgery, and orthopedic surgery overall, is being increasingly scrutinized by payors due to large projected increases in utilization. The unsustainability of the fee-for-service payment system has lead payors to investigate novel value and risk-based contracting strategies on an episode of care basis and on a population health basis. These forays into progressive models for spine surgery have been supported by the successes demonstrated by advanced payor reform programs from The Centers for Medicare and Medicaid Services in other areas of musculoskeletal medicine...
June 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28479161/clinical-utility-of-high-frequency-musculoskeletal-ultrasonography-in-foot-and-ankle-pathology-how-ultrasound-imaging-influences-diagnosis-and-management
#9
Patricia B Delzell, Benjamin A Tritle, Jennifer A Bullen, Stella Chiunda, Michael C Forney
The use of high-frequency (high-resolution) musculoskeletal ultrasonography is increasing and has shown promising utility in many areas of medicine. The utility of musculoskeletal ultrasonography for foot and ankle complaints has not been widely investigated, however. Although some conditions of the foot and ankle are easily diagnosed by physical examination, others can have nonspecific examination findings, making optimal treatment decisions difficult. We hypothesized that high-resolution musculoskeletal ultrasound scanning of the foot and ankle can affect the diagnosis and/or treatment for patients presenting with foot or ankle complaints...
May 4, 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/28476098/developing-quality-indicators-for-the-care-of-patients-with-musculoskeletal-injuries-in-the-emergency-department-study-protocol
#10
Kirsten Strudwick, Anthony Bell, Trevor Russell, Melinda Martin-Khan
BACKGROUND: Musculoskeletal injuries are a common presentation to the Emergency Department (ED). The quality of care provided is important to the patients, clinicians, organisations and purchasers of care. In the context of the increasing burden of musculoskeletal disease, quality of care needs to occur despite financial impacts, variations in care, and pressure to reach time-based performance measures. This study aims to develop a suite of evidence-based quality indicators (QI) which will provide a measure of the quality of care for patients with musculoskeletal injuries in the ED...
May 5, 2017: BMC Emergency Medicine
https://www.readbyqxmd.com/read/28467220/myofascial-manual-lymphatic-drainage-for-burn-trauma-a-service-evaluation
#11
Anna Loskotová, Jitka Loskotová, Ivan Suchanek, Pavel Brychta, Bretislav Lipový
Improving microcirculation in the area of a wound is an important aspect of wound healing. It can be improved by a new manual methodology: myofascial-manual lymphatic drainage (M-MLD). This hybrid technique uses elements of musculoskeletal medicine and manual lymphatic drainage. Through palpation, M-MLD therapeutically affects the functional pathology of soft tissues, with reflection in trigger points, and also the functional pathology of lymphatic system, namely by lymphostasis in particular regional lymph nodes...
May 1, 2017: British Journal of Community Nursing
https://www.readbyqxmd.com/read/28466181/-low-level-laser-therapy-a-narrative-literature-review-on-the-efficacy-in-the-treatment-of-rheumatic-orthopaedic-conditions
#12
REVIEW
A W A Baltzer, D Stosch, F Seidel, M S Ostapczuk
BACKGROUND: In low level laser therapy (LLLT) low wattage lasers are used to irradiate the affected skin areas, joints, nerves, muscles and tendons without any sensation or thermal damage. Although the exact mechanism of its effect is still unknown, it seems beyond dispute that LLLT induces a variety of stimulating processes at the cellular level affecting cell repair mechanisms, the vascular system and lymphatic system. LLLT has been popular among orthopaedic practitioners for many years, whereas university medicine has remained rather sceptical about it...
May 2, 2017: Zeitschrift Für Rheumatologie
https://www.readbyqxmd.com/read/28461641/healthcare-use-and-direct-cost-of-giant-cell-arteritis-a-population-based-study
#13
Matthew J Koster, Sara J Achenbach, Cynthia S Crowson, Hilal Maradit-Kremers, Eric L Matteson, Kenneth J Warrington
OBJECTIVE: To determine the healthcare use and direct medical cost of giant cell arteritis (GCA) in a population-based cohort. METHODS: A well-defined, retrospective population-based cohort of Olmsted County, Minnesota, USA, residents diagnosed with GCA from 1982-2009 was compared to a matched referent cohort from the same population. Standardized cost data (inflation-adjusted to 2014 US dollars) for 1987-2014 and outpatient use data for 1995-2014 were obtained...
May 1, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28460578/belimumab-in-the-management-of-systemic-lupus-erythematosus-an-update
#14
Vladimir Tesar, Zdenka Hruskova
Belimumab is a fully humanised mAb against B lymphocyte stimulator (B-LyS). It is the first biological drug licensed and approved by the US FDA and the European Medicines Agency (EMA) for use in combination with standard immunosuppressants in autoantibody-positive systemic lupus erythematosus (SLE). Areas covered: This manuscript evalues the recent data concerning belimumab's safety and clinical effectiveness and its current place in the treatment of SLE. This includes an overview of the recent data coming from the post-hoc analyses of the BLISS trials, real-life experience with belimumab and the accumulating data on its safety...
May 2, 2017: Expert Opinion on Biological Therapy
https://www.readbyqxmd.com/read/28459754/rehabilitation-after-medial-patellofemoral-ligament-reconstruction
#15
Terrence G McGee, Andrew J Cosgarea, Kevin McLaughlin, Miho Tanaka, Ken Johnson
Patellar instability resulting from subluxation or dislocation is a painful and commonly recurring condition. Retinacular restraints control patellar tracking, limiting the movement of the patella in the trochlear groove. The medial patellofemoral ligament (MPFL) is considered the main soft tissue stabilizer against lateral displacement. Few studies of patellar instability discuss rehabilitation after MPFL reconstruction. In this review, we discuss the phases of rehabilitation after MPFL reconstruction, typical interventions by rehabilitation specialists, and patient-specific guidelines for return to prior level of function...
June 2017: Sports Medicine and Arthroscopy Review
https://www.readbyqxmd.com/read/28455712/macrophages-role-in-tissue-disease-and-regeneration
#16
Lewis Gaffney, Paul Warren, Emily A Wrona, Matthew B Fisher, Donald O Freytes
Inflammation is an essential component of the normal mammalian host tissue response and plays an important role during cardiovascular and musculoskeletal diseases. Given the important role of inflammation on the host tissue response after injury, understanding this process represents essential aspects of biomedical research, tissue engineering, and regenerative medicine. Macrophages are central players during the inflammatory response with an extensive role during wound healing. These cells exhibit a spectrum of activation states that span from pro-inflammatory to pro-healing phenotypes...
2017: Results and Problems in Cell Differentiation
https://www.readbyqxmd.com/read/28455277/evidence-of-benefit-of-telerehabitation-after-orthopedic-surgery-a-systematic-review
#17
Jose Manuel Pastora-Bernal, Rocio Martín-Valero, Francisco Javier Barón-López, María José Estebanez-Pérez
BACKGROUND: In addition to traditional physiotherapy, studies based on telerehabilitation programs have published the results of effectiveness, validity, noninferiority, and important advantages in some neurological, cognitive, and musculoskeletal disorders, providing an opportunity to define new social policies and interventions. OBJECTIVES: The aim of this systematic review is to investigate the effects of telerehabilitation after surgical procedures on orthopedic conditions as well as to describe how interventions are designed and to determine whether telerehabilitation is comparable with conventional methods of delivery...
April 28, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28442205/litigation-related-to-casting-in-orthopaedics-an-analysis-of-claims-against-the-national-health-service-in-england
#18
Jamie A'Court, Rafik Yassa, Charalambos P Charalambous
Orthopaedic casts have been used to treat musculoskeletal conditions for hundreds of years and are still a fundamental component of treating a variety of disorders. As surgical techniques have advanced the frequency of use of orthopaedic casts has declined. With Orthopaedics being is one of the most litigious specialties in medicine we sough to evaluate how this related to casting in Orthopaedics and how we could learn from past mistakes. We analysed litigation claims related to Orthopaedic casts from 1995 to 2010 in which the claims were closed...
April 19, 2017: Injury
https://www.readbyqxmd.com/read/28441294/effects-of-myofascial-release-in-nonspecific-chronic-low-back-pain-a-randomized-clinical-trial
#19
María D Arguisuelas, Juan Francisco Lisón, Daniel Sánchez-Zuriaga, Isabel Martínez-Hurtado, Julio Doménech-Fernández
STUDY DESIGN: Double-blind, randomized parallel sham-controlled trial with concealed allocation and intention-to treat analysis. OBJECTIVE: To investigate the effects of an isolate myofascial release (MFR) protocol on pain, disability, and fear-avoidance beliefs in patients with chronic low back pain (CLBP). SUMMARY OF BACKGROUND DATA: MFR is a form of manual medicine widely used by physiotherapists in the management of different musculoskeletal pathologies...
May 1, 2017: Spine
https://www.readbyqxmd.com/read/28435321/a-behavioral-medicine-intervention-for-community-dwelling-older-adults-with-chronic-musculoskeletal-pain-protocol-for-a-randomized-controlled-trial
#20
Sara Cederbom, Eva Denison, Astrid Bergland
BACKGROUND: Chronic musculoskeletal pain is a major health problem among older adults, particularly those who live alone and/or those who are dependent on formal care. Chronic pain is associated with mobility problems, falls, fear of falling, catastrophizing thoughts, and a lower quality of life. Research shows that physical therapy interventions based on behavioral medicine approaches are beneficial for middle-aged adults with chronic pain. However, there appears to be no previous randomized controlled trials (RCTs) based on this theoretical framework that have examined the effect on older adults with chronic musculoskeletal pain who live alone at home and are dependent on formal care to manage their everyday lives...
2017: Journal of Pain Research
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