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Musculoskeletal medicine

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https://www.readbyqxmd.com/read/28211933/enhanced-bone-tissue-regeneration-using-a-3d-printed-microstructure-incorporated-with-a-hybrid-nano-hydrogel
#1
Dong Nyoung Heo, Nathan J Castro, Se-Jun Lee, Hanaul Noh, Wei Zhu, Lijie Grace Zhang
Three-dimensional (3D) functional constructs with biomimetic mechanical and chemical properties are ideal for various regenerative medicine applications. These properties of 3D fabricated constructs mainly depend on the intrinsic characteristics of the materials and fabrication method. In this respect, the current use of hydrogels for musculoskeletal tissue repair is not ideal due to the lack of suitable mechanical properties, as well as the high biomimetic requirement for success. To overcome this limitation, we developed a novel functionalized hydrogel with bioactive gold nanoparticles (GNPs), reinforcing a 3D printed microstructure via fused deposition modeling (FDM) for bone tissue regeneration...
February 17, 2017: Nanoscale
https://www.readbyqxmd.com/read/28208595/congenital-malformations-in-river-buffalo-bubalus-bubalis
#2
REVIEW
Sara Albarella, Francesca Ciotola, Emanuele D'Anza, Angelo Coletta, Luigi Zicarelli, Vincenzo Peretti
The world buffalo population is about 168 million, and it is still growing, in India, China, Brazil, and Italy. In these countries, buffalo genetic breeding programs have been performed for many decades. The occurrence of congenital malformations has caused a slowing of the genetic progress and economic loss for the breeders, due to the death of animals, or damage to their reproductive ability or failing of milk production. Moreover, they cause animal welfare reduction because they can imply foetal dystocia and because the affected animals have a reduced fitness with little chances of survival...
February 10, 2017: Animals: An Open Access Journal From MDPI
https://www.readbyqxmd.com/read/28199800/preventive-biomechanics
#3
Timothy E Hewett, Nathaniel A Bates
BACKGROUND: Preventive medicine techniques have alleviated billions of dollars' worth of the economic burden in the medical care system through the implementation of vaccinations and screenings before the onset of disease symptoms. Knowledge of biomechanical tendencies has progressed rapidly over the past 20 years such that clinicians can identify, in healthy athletes, the underlying mechanisms that lead to catastrophic injuries such as anterior cruciate ligament (ACL) ruptures. As such, preventive medicine concepts can be applied to noncontact musculoskeletal injuries to reduce the economic burden of sports medicine treatments and enhance the long-term health of athletes...
February 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28188484/estimation-of-attachment-regions-of-hip-muscles-in-ct-image-using-muscle-attachment-probabilistic-atlas-constructed-from-measurements-in-eight-cadavers
#4
Norio Fukuda, Yoshito Otake, Masaki Takao, Futoshi Yokota, Takeshi Ogawa, Keisuke Uemura, Ryota Nakaya, Kazunori Tamura, Robert B Grupp, Amirhossein Farvardin, Mehran Armand, Nobuhiko Sugano, Yoshinobu Sato
PURPOSE: Patient-specific musculoskeletal biomechanical simulation is useful in preoperative surgical planning and postoperative assessment in orthopedic surgery and rehabilitation medicine. A difficulty in application of the patient-specific musculoskeletal modeling comes from the fact that the muscle attachment regions are typically invisible in CT and MRI. Our purpose is to develop a method for estimating patient-specific muscle attachment regions from 3D medical images and to validate with cadaver experiments...
February 10, 2017: International Journal of Computer Assisted Radiology and Surgery
https://www.readbyqxmd.com/read/28185748/validity-of-ultrasound-in-diagnosis-of-tendon-injuries-in-penetrating-extremity-trauma
#5
Narges Mohammadrezaei, Javad Seyedhosseini, Elnaz Vahidi
BACKGROUND: Tendon ruptures are common musculoskeletal injuries all around the world. Correct and timely diagnosis of tendon injuries is obviously important for improving the treatment and minimizing the community costs. Ultrasound is now being considered as one of useful modalities in this area. OBJECTIVE: The preset study is going to validate the diagnostic ability of ultrasound in tendon injuries induced by penetrating extremity trauma. METHODS: In this prospective, observational study, patients with penetrating extremity trauma and suspicion of tendon injuries were enrolled in our study...
January 27, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28178024/the-effects-of-curcuminoids-on-musculoskeletal-pain-a-systematic-review
#6
Andrew Gaffey, Helen Slater, Kylie Porritt, Jared M Campbell
BACKGROUND: Western countries are increasingly using complementary and alternative medicine (CAM) to assist with relieving ailments. Turmeric, from the ginger family Zingiberaceae, has a history of use for medicinal purposes. The polyphenols found in turmeric (curcuminoids) have demonstrated anti-inflammatory and pain relieving properties. With the use of CAMs increasing, it is important for the effectiveness of curcuminoids to be established. OBJECTIVES: To identify the effectiveness of the use of curcuminoids for the amelioration of musculoskeletal pain...
February 2017: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/28165417/characteristics-of-traditional-chinese-medicine-use-in-pediatric-dislocations-sprains-and-strains
#7
Chung-Yen Lu, Hen-Hong Chang, Fung-Chang Sung, Pei-Chun Chen
BACKGROUND AND OBJECTIVES: Dislocations, sprains and strains are common childhood musculoskeletal injuries, requiring medical attention. We investigated the characteristics associated with using traditional Chinese medicine (TCM) for children suffering from these injuries. METHODS: From a nationwide representative insurance database of Taiwan, this cross-sectional study identified 50,769 children with dislocations, sprains and strains under 18 years of age, newly diagnosed between 1999 and 2009, without previous TCM experience...
February 4, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28161721/focal-uptake-at-the-rotator-interval-or-inferior-capsule-of-shoulder-on-18-f-fdg-pet-ct-is-associated-with-adhesive-capsulitis
#8
Radhika Sridharan, Mitchell Philip Engle, Naveen Garg, Wei Wei, Behrang Amini
OBJECTIVE: To determine if focal increased uptake at the rotator interval (RI) and/or inferior capsule (IC) on(18)F-FDG PET/CT ("positive PET") predicts the presence of adhesive capsulitis (AC). MATERIALS AND METHODS: Three populations were retrospectively examined. Group 1 included 1,137 consecutive (18)F-FDG PET/CT studies and was used to determine the prevalence of focal uptake at the RI or IC. Group 2 included 361 cases from a 10-year period with (18)F-FDG PET/CT and MRI of shoulder performed within 45 days of each other and was used to enrich the study group...
February 4, 2017: Skeletal Radiology
https://www.readbyqxmd.com/read/28155840/osteitis-in-the-course-of-pyodema-gangrenosum-case-raport
#9
Andrzej Kaźmierczak-Koćwin, Robert Pieczyrak, Damian Kusz, Eugeniusz Kucharz, Marcin Kusz
We present the case of a male patient admitted to the Department of Orthopaedics and Musculoskeletal Traumatology, Medical University of Silesia (MUS) in Katowice, due to a right hindfoot abscess with calcaneal infiltration and pain in the forehead and the back, with evidence of local inflammation. The patient had a history of ulcerative colitis and sclerosing cholangitis was suspected. During the hospital stay, the patient underwent calcaneal CT, surgery (resection of an inflammatory focus) and MRI of the thoracic and lumbosacral spine, which revealed inflamed spinous processes of the Th10, Th11 and Th12 vertebrae...
November 30, 2016: Ortopedia, Traumatologia, Rehabilitacja
https://www.readbyqxmd.com/read/28149657/evaluation-of-olfactory-function-in-beh%C3%A3-et-s-disease
#10
Lütfi Akyol, Emre Günbey, Rıfat Karlı, Soner Önem, Metin Özgen, Mehmet Sayarlıoğlu
OBJECTIVE: Behçet's disease (BD) is a chronic, relapsing type of vasculitis of unknown etiology and is characterized by oral and urogenital ulcers and ocular inflammation with cutaneous, musculoskeletal, vascular, and nervous system manifestations. Few cases involving the nasal mucosa have been reported in the literature, and the true prevalence of BD remains unknown. Neurological involvement associated with BD might play a more important role in causing olfactory dysfunction than mucosal involvement, but sufficient clinical data are not available on the effect of BD on olfaction in adults...
December 2016: European Journal of Rheumatology
https://www.readbyqxmd.com/read/28149646/vasculitic-syndromes-in-hepatitis-c-virus-a-review
#11
REVIEW
Gaafar Ragab, Mohamed A Hussein
Vasculitis is a remarkable presentation of the extrahepatic manifestations of HCV. According to the presence or absence of cryoglobulins it is subdivided into two main types: cryoglobulinemic vasculitis and non cryoglobulinemic vasculitis based on the attribution of vasculitis to serum cryoglobulins as a pathogenic factor. The attribution of cryoglobulinemia to HCV represents a success story in the history of immunology, microbiology, and clinical medicine. HCV can bind to and invade lymphocytes, consequently triggering an immune response through different mechanisms...
March 2017: Journal of Advanced Research
https://www.readbyqxmd.com/read/28143829/the-value-of-homemade-phantoms-for-training-veterinary-students-in-the-ultrasonographic-detection-of-radiolucent-foreign-bodies
#12
Carolina Mariano Beraldo, Érika Rondon Lopes, Raduan Hage, Maria Cristina F N S Hage
Ingested or penetrating foreign bodies are common in veterinary medicine. When they are radiolucent, these objects become a diagnostic challenge, but they can be investigated sonographically. However, successful object identification depends on the skill of the sonographer. Considering that these cases appear randomly during hospital routines, it is not always possible to train all students to identify them correctly. Therefore, the aim of this study was to produce homemade simulations of radiolucent foreign bodies for veterinary student demonstrations that could be identified sonographically and to evaluate the acceptability, applicability, and usefulness of these simulations according to a visual analog scale questionnaire and subjective questions...
March 1, 2017: Advances in Physiology Education
https://www.readbyqxmd.com/read/28143546/patient-defined-desired-outcome-success-criteria-and-expectation-in-outpatient-physical-therapy-a-longitudinal-assessment
#13
Giorgio Zeppieri, Steven Z George
BACKGROUND: Patient-centered approaches offer an alternative method in evaluating treatment outcomes. This study investigated; 1) if patient's criteria for success (satisfaction of clinical outcomes) changes from pre to post treatment, 2) whether patients who met their success criteria also meet minimal clinical important difference scores (MCIDs), and 3) if patient's success criteria differed from their expected (what the patient believes will occur) and desired (what the patient wants to occur) outcomes following intervention...
January 31, 2017: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/28143544/an-overview-of-the-practitioner-research-and-collaboration-initiative-praci-a-practice-based-research-network-for-complementary-medicine
#14
Amie Steel, David Sibbritt, Janet Schloss, Jon Wardle, Matthew Leach, Helene Diezel, Jon Adams
BACKGROUND: The Practitioner Research and Collaboration Initiative (PRACI) is an innovative, multi-modality practice-based research network (PBRN) that represents fourteen complementary medicine (CM) professions across Australia. It is the largest known PBRN for complementary healthcare in the world and was launched in 2015. The purpose of this paper is to provide an update on the progress of the PRACI project, including a description of the characteristics of PRACI members in order to facilitate further sub-studies through the PRACI PBRN...
February 1, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28134952/pectus-excavatum-a-review-of-diagnosis-and-current-treatment-options
#15
Irfaan Abid, MennatAllah M Ewais, Joseph Marranca, Dawn E Jaroszewski
Osteopathic medicine places a special emphasis on the musculoskeletal system, and understanding how chest wall structure may influence function is critical. Pectus excavatum is a common congenital chest wall defect in which the sternum is depressed posteriorly. Patients may present with complaints of chest wall discomfort, exercise intolerance, and tachycardia. The medical implications, diagnosis, and treatment options for patients with pectus excavatum are reviewed.
February 1, 2017: Journal of the American Osteopathic Association
https://www.readbyqxmd.com/read/28129848/using-the-zebrafish-to-understand-tendon-development-and-repair
#16
J W Chen, J L Galloway
Tendons are important components of our musculoskeletal system. Injuries to these tissues are very common, resulting from occupational-related injuries, sports-related trauma, and age-related degeneration. Unfortunately, there are few treatment options, and current therapies rarely restore injured tendons to their original function. An improved understanding of the pathways regulating their development and repair would have significant impact in stimulating the formulation of regenerative-based approaches for tendon injury...
2017: Methods in Cell Biology
https://www.readbyqxmd.com/read/28125978/expectations-of-pain-and-functioning-in-patients-with-musculoskeletal-disorders-a-cross-sectional-study
#17
Sigrid Skatteboe, Cecilie Røe, Morten Wang Fagerland, Lars-Petter Granan
BACKGROUND: Research has suggested that patient expectations are associated with treatment outcome and evolve along with patient communication within the musculoskeletal field. However, few studies have investigated if or how physical medicine and rehabilitation (PMR) consultations affect the attending patients' expectations regarding pain and functional improvement. Hence, the aims of the present study were to compare patient expectations regarding pain and functional improvement before and after a PMR consultation and to assess patient characteristics, including diagnosis, that could perhaps predict changes in expectations...
January 26, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28119539/inflammatory-mechanisms-in-tendinopathy-towards-translation
#18
REVIEW
Neal L Millar, George A C Murrell, Iain B McInnes
Tendinopathy is a multifactorial spectrum of tendon disorders that affects different anatomical sites and is characterized by activity-related tendon pain. These disorders are common, account for a high proportion (∼30%) of referrals to musculoskeletal practitioners and confer a large socioeconomic burden of disease. Our incomplete understanding of the mechanisms underpinning tendon pathophysiology continues to hamper the development of targeted therapies, which have been successful in other areas of musculoskeletal medicine...
January 25, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/28115867/sonographic-tracking-of-trunk-nerves-essential-for-ultrasound-guided-pain-management-and-research
#19
Ke-Vin Chang, Chih-Peng Lin, Chia-Shiang Lin, Wei-Ting Wu, Manoj K Karmakar, Levent Özçakar
Delineation of architecture of peripheral nerves can be successfully achieved by high-resolution ultrasound (US), which is essential for US-guided pain management. There are numerous musculoskeletal pain syndromes involving the trunk nerves necessitating US for evaluation and guided interventions. The most common peripheral nerve disorders at the trunk region include thoracic outlet syndrome (brachial plexus), scapular winging (long thoracic nerve), interscapular pain (dorsal scapular nerve), and lumbar facet joint syndrome (medial branches of spinal nerves)...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28105733/vitamin-d-supplementation-for-sickle-cell-disease
#20
REVIEW
Htoo Htoo Kyaw Soe, Adinegara Bl Abas, Nan Nitra Than, Han Ni, Jaspal Singh, Abdul Razzak Bin Mohd Said, Ifeyinwa Osunkwo
BACKGROUND: Sickle cell disease is a genetic chronic haemolytic and pro-inflammatory disorder. The clinical manifestations of sickle cell disease result from the presence of mutations on the beta globin genes that generate an abnormal haemoglobin product (called haemoglobin S) within the red blood cell. Sickle cell disease can lead to many complications such as acute chest syndrome, stroke, acute and chronic bone complications (including painful vaso-occlusive crisis, osteomyelitis, osteonecrosis and osteoporosis)...
January 20, 2017: Cochrane Database of Systematic Reviews
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