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https://www.readbyqxmd.com/read/29773272/juvenile-dermatomyositis-latest-advances
#1
REVIEW
Qiong Wu, Lucy R Wedderburn, Liza J McCann
Registries and biobanks for juvenile dermatomyositis (JDM) have generated statistical power to help understand pathogenesis and determine treatment and long-term outcomes in this rare and heterogeneous disease. Genotype, autoantibodies, muscle histology and early clinical features may predict prognosis and guide personalised treatment. While corticosteroids and disease-modifying anti-rheumatic drugs improve outcomes, there remain children who experience refractory disease. Ongoing research into the aberrant immune response and novel biological targets is necessary...
August 2017: Best Practice & Research. Clinical Rheumatology
https://www.readbyqxmd.com/read/29772188/hamstring-and-ankle-flexibility-deficits-are-weak-risk-factors-for-hamstring-injury-in-professional-soccer-players-a-prospective-cohort-study-of-438-players-including-78-injuries
#2
Nicol van Dyk, Abdulaziz Farooq, Roald Bahr, Erik Witvrouw
BACKGROUND: Hamstring injuries remain a significant injury burden in sports such as soccer that involve high-speed running. It has repeatedly been identified as the most common noncontact injury in elite male soccer, representing 12% of all injuries. As the incidence of hamstring injuries remains high, investigations are aimed at better understanding how to prevent hamstring injuries. Stretching to improve flexibility is commonly used in elite-level sports, but risk factor studies have reported contradicting results, leading to unclear conclusions regarding flexibility as a risk factor for hamstring injuries...
May 1, 2018: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29744929/regenerative-medicine-will-make-orthopaedic-implants-obsolete-in-our-time-orthopaedic-research-society-first-annual-meeting-debate-san-diego-march-21-st-2017
#3
Brian Johnstone, Joshua J Jacobs, Linda J Sandell, J Mark Wilkinson
The mission of the Orthopaedic Research Society is to promote and advance musculoskeletal research worldwide. With this in mind, the Annual Meeting Program Committee sought to establish a debate as a key component of the meeting. Our purpose was to provoke discussion on topics that are core to our mission and to engage all constituencies within the society by examining questions of broad relevance. To this end, the topic "Regenerative medicine will make orthopaedic implants obsolete in our time" was selected as the title of the inaugural debate...
May 10, 2018: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/29741408/shifting-perspectives-on-pain-management-after-an-interprofessional-international-service-learning-experience-a-qualitative-assessment-of-pilot-data
#4
Catherine D Noonan, Sarah Scow, Brittany A Sheagley, Jennifer Bunn
Interprofessional education and international service learning (ISL) experiences are increasing in healthcare education and have the potential to broaden healthcare providers' strategies to manage patients' pain. After the addition of a physical therapy (PT) cohort to an existing interprofessional ISL, survey data was collected for program evaluation. Responses indicated altered ideation regarding the role of PT in pain management, and this theme was investigated further. Following two one-week interprofessional ISL experiences in Honduras in 2015 (Y1) and 2016 (Y2), participating students and preceptors in pharmacy, physician assistant and osteopathic medicine and Y1 PT preceptors were surveyed regarding their impressions of the PT cohort and the PT profession in general...
May 9, 2018: Journal of Interprofessional Care
https://www.readbyqxmd.com/read/29736572/hyaluronic-acid
#5
Hélder Pereira, Duarte Andre Sousa, António Cunha, Renato Andrade, J Espregueira-Mendes, J Miguel Oliveira, Rui L Reis
In recent times, the field of tissue engineering and regenerative medicine (TERM) has considerably increased the extent of therapeutic strategies for clinical application in orthopedics. However, TERM approaches have its rules and requirements, in the respect of the biologic response of each tissue and bioactive agents which need to be considered, respected, and subject of ongoing studies. Different medical devices/products have been prematurely available on the market and used in clinics with limited success...
2018: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29731951/advanced-computational-methods-in-bio-mechanics
#6
REVIEW
Waleed M S Al Qahtani, Mohamed I El-Anwar
A novel partnership between surgeons and machines, made possible by advances in computing and engineering technology, could overcome many of the limitations of traditional surgery. By extending surgeons' ability to plan and carry out surgical interventions more accurately and with fewer traumas, computer-integrated surgery (CIS) systems could help to improve clinical outcomes and the efficiency of healthcare delivery. CIS systems could have a similar impact on surgery to that long since realised in computer-integrated manufacturing...
April 15, 2018: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29729782/rehabilitation-medicine-approaches-to-pain-management
#7
REVIEW
Andrea L Cheville, Sean R Smith, Jeffrey R Basford
Rehabilitation medicine offers strategies that reduce musculoskeletal pain, targeted approaches to alleviate movement-related pain, and interventions to optimize patients' function despite the persistence of pain. These approaches fall into four categories: modulating nociception, stabilizing and unloading painful structures, influencing pain perception, and alleviating soft tissue musculotendinous pain. Incorporating these interventions into individualized, comprehensive pain management programs offers the potential to empower patients and limit pain associated with mobility and required daily activities...
June 2018: Hematology/oncology Clinics of North America
https://www.readbyqxmd.com/read/29724151/physical-microenvironment-based-inducible-scaffold-for-stem-cell-tenogenesis-and-tendon-regeneration
#8
Hong Zhang, Meng-Fei Liu, Ri-Chun Liu, Wei-Liang Shen, Zi Yin, Xiao Chen
Tendon injuries are common musculoskeletal system disorders, but the tendons have poor regeneration ability. To address this issue, tendon tissue engineering provides potential strategies for future therapeutic treatment. Elements of the physical microenvironment, such as the mechanical force and surface topography, play a vital role in regulating stem cell fate, enhancing the differentiation efficiency of seed cells in tendon tissue engineering. Various inducible scaffolds have been widely explored for tendon regeneration, and scaffold-enhancing modifications have been extensively studied...
May 4, 2018: Tissue Engineering. Part B, Reviews
https://www.readbyqxmd.com/read/29708945/a-musculoskeletal-look-to-sarcopenia-where-do-should-the-physical-and-rehabilitation-medicine-physicians-physiatrists-stand
#9
EDITORIAL
Levent Özçakar, Ayşe Merve Ata, Michael Quittan, Xanthi Michail
No abstract text is available yet for this article.
June 2018: International Journal of Rehabilitation Research. Revue Internationale de Recherches de Réadaptation
https://www.readbyqxmd.com/read/29703193/patient-house-calls-in-attica-and-thessaloniki-greece-2005-2015-a-model-for-out-of-hospital-multispecialty-emergency-medicine
#10
George Theocharis, Spyridon G Barbas, Theodore Spiropoulos, Petroula E Stamouli, Dimitrios N Perdikis, Matthew E Falagas
BACKGROUND: The SOS-doctors are a network of physicians who perform house-call visits in the areas of Attica and Thessaloniki, Greece. METHODS: Patients requesting medical services by the SOS doctors during the period 1/1/2005 - 31/12/2015 were eligible for inclusion in this retrospective analysis. RESULTS: During this period 335, 212 home visits were performed. Females used this service more frequently compared to males (60.5% versus 39.5%)...
April 27, 2018: BMC Health Services Research
https://www.readbyqxmd.com/read/29694591/-health-pain-and-daily-activities-among-elderly-people-practicing-lian-gong-and-sedentary-elderly-people
#11
Vanessa Cristina Dias Bobbo, Danilo Donizetti Trevisan, Maria Clara Estanislau do Amaral, Eliete Maria Silva
It is a well-known fact that the practice of physical activity on a regular basis among elderly people contributes to the prevention and reduction of pain, as well as promote active ageing. Based on this premise, the scope of this study was to evaluate the presence of chronic pain among elderly people attended in a primary health care unit in a city in the interior of Sao Paulo State, Brazil, by comparing those who practice Chinese gymnastics (Lian Gong) and the sedentary. Sixty elderly people were divided between 30 sedentary and 30 who participate in a group practicing Lian Gong...
April 2018: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/29693032/survey-of-medical-students-attitude-and-knowledge-toward-physical-medicine-and-rehabilitation-in-isfahan-university-of-medical-sciences
#12
Saeed Khosrawi, Hadis Ramezanian, Roya Mollabashi
CONTEXT: Physical medicine and rehabilitation (PMR) is a specialized clinical field of musculoskeletal diseases and physical impairment that is unknown for most of the medical students. AIMS: This study aimed to assess medical students' attitude and knowledge toward PMR and its role in the diagnosis and treatment of musculoskeletal diseases. SETTING AND DESIGN: This cross-sectional study was done on 175 medical students of Isfahan University of Medical Sciences from 2015 to 2016...
2018: Journal of Education and Health Promotion
https://www.readbyqxmd.com/read/29686821/acute-effect-of-different-concentrations-of-cayenne-pepper-cataplasm-on-sensory-motor-functions-and-serum-levels-of-inflammation-related-biomarkers-in-healthy-subjects
#13
Nejc Sarabon, Stefan Löfler, Jan Cvecka, Wolfgang Hübl, Sandra Zampieri
Physical medicine therapies are often used in treating widespread musculoskeletal disorders, such as neck and low back pain. Herbal cataplasms containing rubefacient substances, such as Cayenne pepper, or galenic preparations like Munari cataplasm are commonly used as natural medications to treat painful areas. In this paper we show the effects of a 20-min application of Cayenne pepper and kaolin powder cataplasm (CPC) on healthy subjects. Treatment effects were evaluated by cold/hot feeling on visual analogue scale, blood pressure, body temperature, skin light touch sensations, two-point discrimination, and pain threshold to a mechanical stimulus, before and immediately after, 15 min after and 30 min after different concentration of Cayenne pepper in CPC preparation on healthy subjects...
January 12, 2018: European Journal of Translational Myology
https://www.readbyqxmd.com/read/29674346/from-microscopic-to-macroscopic-sports-injuries-applying-the-complex-dynamic-systems-approach-to-sports-medicine-a-narrative-review
#14
REVIEW
Rafel Pol, Robert Hristovski, Daniel Medina, Natalia Balague
A better understanding of how sports injuries occur in order to improve their prevention is needed for medical, economic, scientific and sports success reasons. This narrative review aims to explain the mechanisms that underlie the occurrence of sports injuries, and an innovative approach for their prevention on the basis of complex dynamic systems approach. First, we explain the multilevel organisation of living systems and how function of the musculoskeletal system may be impaired. Second, we use both, a constraints approach and a connectivity hypothesis to explain why and how the susceptibility to sports injuries may suddenly increase...
April 19, 2018: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/29669396/discordance-between-population-impact-of-musculoskeletal-disorders-and-scientific-interest-a-bibliometric-study
#15
Anthony V Perruccio, Calvin Yip, J Denise Power, Mayilee Canizares, Elizabeth M Badley
OBJECTIVE: Musculoskeletal disorders (MSDs) are a leading cause of healthy years lost due to premature mortality and disability. Our objective was to investigate whether MSDs were commensurably represented within the published health literature. METHODS: MEDLINE bibliometric data were retrieved for 2016 and 2011. The 25 disease branches, including MSDs, were ranked according to published paper counts, proportion of all publications, and increase in publications from 2011 to 2016...
April 18, 2018: Arthritis Care & Research
https://www.readbyqxmd.com/read/29665386/enzymatically-crosslinked-and-mechanically-tunable-silk-fibroin-pullulan-hydrogels-for-mesenchymal-stem-cells-delivery
#16
Tao Li, Xiongbo Song, Changmei Weng, Xin Wang, Jiangyi Wu, Li Sun, Xiaoyuan Gong, Wei-Nan Zeng, Liu Yang, Cheng Chen
Hydrogels with good biocompatibility, proper degradation rates, and tissue-matched elasticity are widely used in tissue engineering, regenerative medicine, and drug delivery. In this study, enzymatically crosslinked biocompatible hydrogels were successfully developed using silk fibroin (SF) and pullulan (PL) under physiological conditions in the presence of both horseradish peroxidase (HRP) and hydrogen peroxide (H2 O2 ). A series of properties of the hydrogels including gelation time, equilibrium swelling, enzyme degradation, morphology, rheological property, and compression modulus of SF/PL hydrogels were studied by varying the concentration of PL...
April 14, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29662915/patient-perspectives-of-midlevel-providers-in-orthopaedic-sports-medicine
#17
Blaine T Manning, Daniel D Bohl, Charles P Hannon, Michael L Redondo, David R Christian, Brian Forsythe, Shane J Nho, Bernard R Bach
Background: Midlevel providers (eg, nurse practitioners and physician assistants) have been integrated into orthopaedic systems of care in response to the increasing demand for musculoskeletal care. Few studies have examined patient perspectives toward midlevel providers in orthopaedic sports medicine. Purpose: To identify perspectives of orthopaedic sports medicine patients regarding midlevel providers, including optimal scope of practice, reimbursement equity with physicians, and importance of the physician's midlevel provider to patients when initially selecting a physician...
April 2018: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/29658673/-application-of-rehabilitation-medicine-in-enhanced-recovery-after-surgery
#18
Haijun Li, Zuobing Chen
Enhanced recovery after surgery (ERAS) has been widely used in perioperative optimization. As an important component of ERAS, rehabilitation medicine mainly focuses on perioperative physical fitness management, respiratory training, exercise training to reduce the incidence of postoperative pulmonary infection, improve gastrointestinal and cardiopulmonary function. This paper explains rehabilitation medicine for respiratory, musculoskeletal, cardiovascular and digestive systems during the perioperative period...
May 25, 2017: Zhejiang da Xue Xue Bao. Yi Xue Ban, Journal of Zhejiang University. Medical Sciences
https://www.readbyqxmd.com/read/29625732/healthcare-use-patterns-and-economic-burden-of-chronic-musculoskeletal-pain-in-children-before-diagnosis
#19
Frances Tian, Patsy Guittar, Melissa Moore-Clingenpeel, Gloria Higgins, Stacy P Ardoin, Charles H Spencer, Karla Jones, Bethanne Thomas, Shoghik Akoghlanian, Sharon Bout-Tabaku
OBJECTIVES: To evaluate the healthcare use and costs of amplified musculoskeletal pain syndrome (AMPS) in children before diagnosis. STUDY DESIGN: We performed a retrospective study in children with AMPS at a pediatric rheumatology clinic between 2010 and 2014. Data were abstracted on 80 patients after primary rheumatic diseases were excluded. Healthcare visits, medications and diagnostic testing that occurred in the years before diagnosis were collected. The Medical Expenditure Panel Survey was used to estimate visit costs...
April 3, 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29622248/editorial-commentary-we-promis%C3%A2-one-more-patient-reported-outcome-questionnaire
#20
EDITORIAL
Peter D Fabricant
The Patient-Reported Outcomes Measurement Information System (PROMIS) is a set of powerful computer adaptive patient-reported outcome tools that have the ability to evaluate physical, mental, and social health measures in adults and children. It has recently been implemented for a variety of musculoskeletal conditions, but the psychometric properties of the scores in the setting of orthopaedic sports medicine and arthroscopy are incompletely explored. Determining normative data and responsiveness in cohorts of interest is vital if these measures are to be used to track patient-reported outcomes postoperatively...
April 2018: Arthroscopy: the Journal of Arthroscopic & related Surgery
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