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https://www.readbyqxmd.com/read/29243035/systemic-lupus-erythematosus-and-ocular-involvement-an-overview
#1
REVIEW
Rosanna Dammacco
Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease of undefined etiology and with remarkably heterogeneous clinical features. Virtually any organ system can be affected, including the eye. SLE-related eye involvement can be diagnosed in approximately one-third of the patients and is usually indicative of disease activity. An early diagnosis and the adoption of suitable therapeutic measures are necessary to prevent sight-threatening consequences, especially in patients with juvenile SLE. Periocular lesions, such as eyelid involvement and orbital inflammation, are relatively rare and, in case of orbital masses, may require a biopsy control...
December 14, 2017: Clinical and Experimental Medicine
https://www.readbyqxmd.com/read/29242983/-stressed-country-doctor-with-acute-visual-loss-clear-diagnosis
#2
D Heinrich, M Ulbig, N Feucht, M Maier
No abstract text is available yet for this article.
December 14, 2017: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/29241233/hyperbaric-oxygen-in-the-treatment-of-acute-retinal-artery-occlusion
#3
Mark J Elder, John A Rawstron, Michael Davis
INTRODUCTION: Acute retinal artery occlusion (ARAO) is a major cause of sudden, painless visual loss, often leaving no useful vision in the affected eye. Its incidence is cited at 0.85 per 100,000 persons per year but may be higher because of under-reporting. The natural history is difficult to study, but a spontaneous resolution rate of < 1-8% for acute, non-arteritic ARAO has been cited. Occurrence in an only eye is devastating for the patient. There is currently no consensus regarding management of ARAO and little evidence to support any treatment modality...
December 2017: Diving and Hyperbaric Medicine: the Journal of the South Pacific Underwater Medicine Society
https://www.readbyqxmd.com/read/29237466/rapid-detection-of-infectious-bovine-rhinotracheitis-virus-using-recombinase-polymerase-amplification-assays
#4
Peili Hou, Hongmei Wang, Guimin Zhao, Chengqiang He, Hongbin He
BACKGROUND: Infectious bovine rhinotracheitis virus (IBRV) is a major pathogen in cattle and has led to significant economic losses to the dairy industry worldwide, and therefore a more optimal method for the rapid diagnosis of IBRV infection is highly needed. In this study, we described the development of a lateral flow dipstrip (LFD) of isothermal recombinase polymerase amplification (RPA) method for rapid detection of IBRV. METHODS: Distinct regions were selected as a candidate target for designing the LFD-RPA primers and probes...
December 13, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/29222573/incidence-and-causes-of-overdiagnosis-of-optic-neuritis
#5
Leanne Stunkel, Nathan H Kung, Bradley Wilson, Collin M McClelland, Gregory P Van Stavern
Importance: Diagnostic error is an important source of medical error. Overdiagnosis of optic neuritis may prompt unnecessary and costly diagnostic tests, procedures, and treatments. Objective: To assess the incidence of and characterize factors contributing to overdiagnosis of acute optic neuritis. Design, Setting, and Participants: In this retrospective clinic-based cross-sectional study of new patient encounters, 122 patients referred for acute optic neuritis at a university-based Midwestern neuro-ophthalmology clinic between January 2014 and October 2016 were studied...
December 7, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/29207977/acute-zonal-occult-outer-retinopathy-azoor-a-case-report-of-vision-improvement-after-intravitreal-injection-of-ozurdex
#6
Yi Chun Kuo, Nancy Chen, Rong Kung Tsai
BACKGROUND: AZOOR was first described by Gass in 1993 as a syndrome with rapid loss of one or more extensive zones of the outer retinal segments. It is characterized by photopsia, minimal funduscopic changes, and electroretinographic abnormalities. The efficacy of systemic steroids in treating AZOOR has been previously described and advocated by the concept of autoimmune retinopathy. However, the use of intravitreal of sustained-released steroid had not been mentioned to date. CASE PRESENTATION: A 34-year-old man had sudden onset of central scotoma and photopsia in the left eye...
December 6, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/29201538/vision-in-stroke-cohort-profile-overview-of-visual-impairment
#7
Fiona J Rowe
Aim: To profile the full range of visual disorders from a large prospective observation study of stroke survivors referred by stroke multidisciplinary teams to orthoptic services with suspected visual problems. Methods: Multicenter prospective study undertaken in 20 acute Trust hospitals. Standardized screening/referral forms and investigation forms documented data on referral signs and symptoms plus type and extent of visual impairment. Results: Of 1,345 patients referred with suspected visual impairment, 915 were recruited (59% men; mean age at stroke onset 69 years [SD 14])...
November 2017: Brain and Behavior
https://www.readbyqxmd.com/read/29200859/abnormal-regional-spontaneous-neural-activity-in-visual-pathway-in-retinal-detachment-patients-a-resting-state-functional-mri-study
#8
Xin Huang, Dan Li, Hai-Jun Li, Yu-Lin Zhong, Shelby Freeberg, Jing Bao, Xian-Jun Zeng, Yi Shao
Objective: The aim of the study was to investigate changes of brain neural homogeneity in retinal detachment (RD) patients using the regional homogeneity (ReHo) method to understand their relationships with clinical features. Materials and methods: A total of 30 patients with RD (16 men and 14 women), and 30 healthy controls (HCs) (16 men and 14 women) closely matched in age and sex were recruited. Resting-state functional magnetic resonance imaging scans were performed for all subjects...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29174243/evaluation-and-efficacy-of-long-length-pronova-xr-bioabsorbable-polymer-stent-in-the-treatment-of-long-coronary-lesions
#9
M S Hiremath
AIM: The study aims an observational registry of the long and extra-long length (>33mm) Pronova XR stents in patients with long coronary lesions (>30mm) in a prospective real world study. METHODS AND RESULTS: Current study was conducted at Ruby Hall Clinic Pune, between July 2012 and July 2013 including 30 patients who underwent PTCA using long and extra-long Pronova XR stents. Among the stents used, one stent - 33mm, 2 stents - 38mm, 5 stents - 43mm and 25 stents were of 48mm in length...
November 2017: Indian Heart Journal
https://www.readbyqxmd.com/read/29171798/orbital-lymphatic-venous-malformation-with-concomitant-spontaneous-orbital-arteriovenous-fistula-case-report
#10
Bunyada Putthirangsiwong, Dinesh Selva, Weerawan Chokthaweesak, Ekachat Chanthanaphak, Sirintara Singhara Na Ayudhaya
The authors describe the case of an 11-year-old boy with no history of prior trauma, who experienced acute proptosis and visual loss while showering. Diagnostic carotid artery angiography revealed an orbital lymphatic-venous malformation (LVM) concomitant with an intraorbital arteriovenous fistula. The patient was treated with transvenous coil and N-butyl cyanoacrylate glue embolization, combined with direct percutaneous glue injection into the LVM followed by excision. There was good clinical and radiological response without recurrence at the 2-year follow-up...
November 24, 2017: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/29162667/reperfusion-of-occluded-branch-retinal-arteries-by-transluminal-nd-yag-laser-embolysis-combined-with-intravenous-thrombolysis-of-urokinase
#11
Fang Chai, Shanshuang Du, Xiquan Zhao, Runsheng Wang
Purpose.  To report successful treatment with transluminal Nd:YAG laser embolysis (TYE) combined with urokinase thrombolysis for reperfusion of occluded branch retinal arteries with visible emboli. Methods A total of 34 eyes from 34 patients with acute, severe vision loss secondary to a branch retinal artery occlusion with visible emboli and retinal whitening were examined. Each patient was administered TYE therapy, which focused on the embolus, using an ocular contact lens; a 0.3-0.9 mJ laser pulse was delivered directly and gradually according to the reaction...
November 21, 2017: Bioscience Reports
https://www.readbyqxmd.com/read/29155694/paracentral-acute-middle-maculopathy-in-primary-congenital-glaucoma
#12
Yavuz K Aribas, Zeynep Aktas, Kemal Bayrakceken, Tuba Atalay, Sengul Ozdek
PURPOSE: To report a case of primary congenital glaucoma associated with paracentral acute middle maculopathy. METHODS: A case report. RESULTS: A 14-year-old girl with undiagnosed primary congenital glaucoma was referred for the evaluation of sudden vision loss a week after the initial symptoms. Visual acuity was counting fingers at 2 m in the right eye. Examination of her right eye revealed corneal stromal scar like Haab striae, splinter hemorrhage at the temporal border of the optic disk, perivenular hemorrhage, and fern-like white area at the macula...
November 16, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/29145966/outcome-evaluation-of-staged-treatment-for-bicondylar-tibial-plateau-fractures
#13
Vincenzo Giordano, Ney Pecegueiro do Amaral, Hilton A Koch, Rodrigo Pires E Albuquerque, Felipe Serrão de Souza, José Félix Dos Santos Neto
BACKGROUND: The universal accepted strategy for treating high-energy tibial plateau fractures remains a topic of ongoing debate. The challenge for the practicing orthopaedic trauma surgeon is to provide anatomical articular fracture reduction, with successfully managing the complex soft-tissue injury that is commonly present at patient admission. The primary aim of the actual study was to evaluate the results of a staged protocol for the treatment of high-energy bicondylar tibial plateau fractures...
October 2017: Injury
https://www.readbyqxmd.com/read/29142145/clinical-course-therapeutic-responses-and-outcomes-in-relapsing-mog-antibody-associated-demyelination
#14
Sudarshini Ramanathan, Shekeeb Mohammad, Esther Tantsis, Tina Kim Nguyen, Vera Merheb, Victor S C Fung, Owen Bruce White, Simon Broadley, Jeannette Lechner-Scott, Steve Vucic, Andrew P D Henderson, Michael Harry Barnett, Stephen W Reddel, Fabienne Brilot, Russell C Dale
OBJECTIVE: We characterised the clinical course, treatment and outcomes in 59 patients with relapsing myelin oligodendrocyte glycoprotein (MOG) antibody-associated demyelination. METHODS: We evaluated clinical phenotypes, annualised relapse rates (ARR) prior and on immunotherapy and Expanded Disability Status Scale (EDSS), in 218 demyelinating episodes from 33 paediatric and 26 adult patients. RESULTS: The most common initial presentation in the cohort was optic neuritis (ON) in 54% (bilateral (BON) 32%, unilateral (UON) 22%), followed by acute disseminated encephalomyelitis (ADEM) (20%), which occurred exclusively in children...
November 15, 2017: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/29133663/combined-central-retinal-artery-and-vein-occlusion-with-optic-perineuritis-following-herpes-zoster-dermatitis-in-an-immunocompetent-child
#15
Reema Bansal, Ramandeep Singh, Aastha Takkar, Vivek Lal
A 15-year-old healthy boy developed acute, rapidly progressing visual loss in left eye following herpes zoster dermatitis, with a combined central retinal artery occlusion (CRAO) and central retinal vein occlusion (CRVO), along with optic perineuritis. Laboratory tests were negative. Despite an empirical, intensive antiviral treatment with systemic corticosteroids, and vision could not be restored in the affected eye. Herpes zoster dermatitis, in an immunocompetent individual, may be associated with a combined CRAO and CRVO along with optic perineuritis, leading to profound visual loss...
November 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29122818/optical-coherence-tomographic-angiography-identifies-peripapillary-microvascular-dilation-and-focal-non-perfusion-in-giant-cell-arteritis
#16
Eric D Gaier, Aubrey L Gilbert, Dean M Cestari, John B Miller
AIMS: We set out to determine the optical coherence tomographic angiography (OCT-A) characteristics of arteritic anterior ischaemic optic neuropathy (AAION) in the context of giant cell arteritis (GCA). METHODS: This is an observational case series of four patients with AAION secondary to GCA, three with unilateral AAION and one with bilateral AAION. We reviewed the charts, fundus photography, visual fields, fluorescein angiography (FA) and OCT-A images for all patients to identify a unifying theme in a range of AAION clinical severity...
November 9, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/29118839/acute-angle-closure-glaucoma-a-potential-blind-spot-in-critical-care
#17
Anna Petsas, George Chapman, Richard Stewart
We report a case of a 69-year-old gentleman who developed an acutely painful eye with loss of visual acuity whilst on the critical care unit. He was admitted three days previously with an infective exacerbation of chronic obstructive pulmonary disease requiring invasive mechanical ventilation. In addition, he received intravenous antibiotics, steroids, nebulised bronchodilators and intravenous aminophylline, together with noradrenaline for blood pressure support. On development of visual symptoms, an emergency ophthalmology review diagnosed acute angle closure glaucoma...
August 2017: Journal of the Intensive Care Society
https://www.readbyqxmd.com/read/29105618/hemispatial-neglect-following-right-hemisphere-stroke-clinical-course-and-sensitivity-of-diagnostic-tasks
#18
Marianne E Klinke, Haukur Hjaltason, Guðný Berg F Ra Tryggvadóttir, Helga Jónsdóttir
Background Stroke patients with severe symptoms of hemispatial neglect (HN) are known to experience a weaker recovery than those less affected from the outset. Correct identification of HN is therefore important throughout the course of rehabilitation. Objectives To explore: (i) the course of clinical symptoms in stroke patients with moderate/severe HN from acute setting to home, (ii) changes in sensitivity of diagnostic tasks over time, and (iii) agreement between the researcher's and patients' HN assessments...
November 4, 2017: Topics in Stroke Rehabilitation
https://www.readbyqxmd.com/read/29105298/prenatal-cocaine-exposure-disrupts-the-dopaminergic-system-and-its-postnatal-responses-to-cocaine
#19
Elizabeth Riley, Valerie Maymi, Stephanie Pawlyszyn, Yu Lili, Irina V Zhdanova
Impaired attention is the hallmark consequence of prenatal cocaine exposure (PCE), affecting brain development, learning, memory and social adaptation starting at an early age. To date, little is known about the brain structures and neurochemical processes involved in this effect. Through focusing on the visual system and employing zebrafish as a model, we show that PCE reduces expression of dopamine receptor Drd1, with levels reduced in the optic tectum and other brain regions, except the telencephalon. Organism-wide, PCE results in a 1...
November 3, 2017: Genes, Brain, and Behavior
https://www.readbyqxmd.com/read/29084330/characterizing-the-natural-history-of-visual-function-in-choroideremia-using-microperimetry-and-multimodal-retinal-imaging
#20
RANDOMIZED CONTROLLED TRIAL
Jasleen K Jolly, Kanmin Xue, Thomas L Edwards, Markus Groppe, Robert E MacLaren
Purpose: Centripetal retinal degeneration in choroideremia (CHM) leads to early visual field restriction and late central vision loss. The latter marks an acute decline in quality of life but visual prognostication remains challenging. We investigated visual function in CHM by correlating best-corrected visual acuity (BCVA), microperimetry and multimodal imaging. Methods: Fifty-six consecutive CHM patients attending Oxford Eye Hospital were examined with BCVA, 10-2 microperimetry, optical coherence tomography, and fundus autofluorescence (AF)...
October 1, 2017: Investigative Ophthalmology & Visual Science
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