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Acute visual loss

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https://www.readbyqxmd.com/read/29054018/isolated-aphasia-in-the-emergency-department-the-likelihood-of-ischemia-is-low
#1
Gabriel Casella, Rafael H Llinas, Elisabeth B Marsh
OBJECTIVE: Aphasia is a common presentation of ischemic stroke, often diagnosed in the acute setting using tools such as the NIH Stroke Scale (NIHSS). Due to the vascular distribution of the middle cerebral artery, it is often accompanied by other symptoms such as weakness, sensory loss, or visual changes. Isolated aphasia due to ischemia is possible, but language problems mimicking aphasia syndromes can also be seen with other diagnoses such as metabolic abnormalities or dementia. In this study, we determine the incidence of aphasia-only strokes using the NIHSS, and factors associated with a higher likelihood of ischemia...
October 16, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29042528/-a-case-of-ruptured-anterior-communicating-artery-aneurysm-with-visual-field-defects-and-deteriorating-to-severe-vision-loss
#2
Kazuki Sakakura, Go Ikeda, Yasunobu Nakai, Noriyuki Watanabe, Masanari Shiigai, Kazuya Uemura, Tetsuya Yamamoto, Akira Matsumura
Although Terson's syndrome is a well-known cause of vision loss due to intracerebral aneurysm rupture, optic nerve neuropathy can also occur because of other causes. Here, we report such a case, i.e., a ruptured anterior communicating artery aneurysm accompanied by vision loss and visual field disturbances due to a cause other than Terson's syndrome. A 47-year-old man presented with right superior altitudinal hemianopia. Computed tomography (CT) showed subarachnoid hemorrhage (SAH), and three-dimensional CT angiography revealed an anterior communicating artery aneurysm...
October 2017: Brain and Nerve, Shinkei Kenkyū No Shinpo
https://www.readbyqxmd.com/read/29035183/atypical-presentation-of-acute-angle-closure-glaucoma-in-maroteaux-lamy-mucopolysaccharidosis-with-patent-prophylactic-laser-peripheral-iridotomy-a-case-report
#3
Malini Veerappan, Garrick Chak, Christine Shieh, Pratap Challa
INTRODUCTION: Maroteaux-Lamy syndrome (MLS) is a rare progressive condition characterized by inflammation and scarring of multiple organs. Ocular complications caused by anterior segment abnormalities commonly cause visual impairment in MLS. Angle-closure glaucoma is one such complication, but there are limited data on presentation, workup, and management of this condition. CASE PRESENTATION: This case report describes an atypical presentation of acute angle-closure glaucoma in a patient with MLS despite a prior prophylactic laser peripheral iridotomy-which would typically prevent an acute angle-closure attack-that was patent and intact at the time of angle closure...
2017: Permanente Journal
https://www.readbyqxmd.com/read/29025172/-anti-myelin-oligodendrocyte-glycoprotein-antibodies-in-paediatric-patients-with-optic-neuritis
#4
Helmut Tegetmeyer, Andreas Merkenschlager
Background Myelin oligodendrocyte glycoprotein (MOG) is located on the surface of oligodendrocytes and myelin in the central nervous system. MOG-IgG is associated with acute disseminated encephalomyelitis (ADEM), relapsing and bilateral optic neuritis (NNO), and transverse myelitis (TM) in both paediatric and adult patients. The combination of NNO and TM or other inflammatory brain lesions is a typical feature of neuromyelitis optica spectrum disorders (NMO-SD) which are associated with specific pathogenic autoantibodies against the water channel aquaporin-4 (AQP4-IgG)...
October 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/29020430/acute-exudative-polymorphous-paraneoplastic-vitelliform-maculopathy-managed-with-intravitreal-aflibercept
#5
Kaan Gündüz, Gökçen Çöndü, Carol L Shields
The authors report on two patients with bilateral acute exudative polymorphous paraneoplastic vitelliform maculopathy (AEPPVM) treated with intravitreal aflibercept (Eylea; Regeneron, Tarrytown, NY [marketed locally in Turkey by Bayer]). Underlying malignancy had been treated in each case, including breast carcinoma in one case and colon carcinoma in the other case. A macular vitelliform lesion was noted in the right eye and atrophic retinal pigment epithelial (RPE) changes were noted in the left eye of each case...
October 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/29016525/paracentral-acute-middle-maculopathy-in-susac-syndrome
#6
Ali S Haider, Deepa Viswanathan, David Williams, Peter Davies
PURPOSE: To present the first reported case of paracentral acute middle maculopathy in association with Susac syndrome. METHOD: Case report. RESULTS: A young female patient presented with unilateral sudden loss of vision of her right eye to count fingers. There were numerous cotton wool spots in a multifocal pattern concentrated around the right macula and optic disk. Clinical examination and spectral domain optical coherence tomography imaging were consistent with paracentral acute middle maculopathy, and fluorescein angiography showed features of retinal arteriole vasculitis...
October 9, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28979743/comparison-of-treatment-response-to-intravitreal-injection-of-triamcinolone-bevacizumab-and-combined-form-in-patients-with-central-retinal-vein-occlusion-a-randomized-clinical-trial
#7
Ghader Motarjemizadeh, Miaad Rajabzadeh, Naser Samadi Aidenloo, Rohollah Valizadeh
BACKGROUND: Central retinal vein occlusion (CRVO), is the second-most common disorder after diabetic retinopathy that threatens the vision related to retinal vessels. One of the main reasons of vision loss is CRVO in acute and chronic forms. OBJECTIVE: The aim of this study was to investigate the response to intravitreal injection of triamcinolone, bevacizumab, and a combined form in patients with CRVO. METHODS: This study was a double-blinded randomized clinical trial conducted on patients with CRVO who were referred to the ophthalmology clinic of Urmia Imam Khomeini Hospital from May 2015 to May 2016...
August 2017: Electronic Physician
https://www.readbyqxmd.com/read/28972988/orbital-complications-of-paranasal-sinusitis-in-taiwan-1988-through-2015-acute-ophthalmological-manifestations-diagnosis-and-management
#8
Yi-Sheng Chang, Po-Lin Chen, Jia-Horung Hung, Hsiao-Yen Chen, Chun-Chieh Lai, Chun-Yen Ou, Chia-Ming Chang, Chien-Kuo Wang, Hon-Chun Cheng, Sung-Huei Tseng
PURPOSE: Paranasal sinusitis is widespread and can lead to orbital complications, blindness, and death. However, the correlation between ophthalmological findings and disease staging remains unclear. This study aimed to investigate the staging, acute ophthalmological manifestations, diagnosis, management, and outcomes of orbital complications of paranasal sinusitis during a 27-year period. METHODS: We retrospectively reviewed the medical records of all patients with orbital complications of paranasal sinusitis hospitalized at the National Cheng Kung University Hospital, a medical center in Taiwan during 1988-2015...
2017: PloS One
https://www.readbyqxmd.com/read/28957954/capnocytophaga-canimorsus-endophthalmitis-after-cataract-surgery-linked-to-salivary-dog-to-human-transmission
#9
François Thommen, Onya Opota, Gilbert Greub, Katia Jaton, Yan Guex-Crosier, Thomas J Wolfensberger, Alexandre Matet
PURPOSE: To describe a case of acute postoperative bacterial endophthalmitis because of Capnocytophaga canimorsus after cataract surgery, with probable contamination through salivary droplets of dog two days after the procedure. METHODS: An 83-year-old woman who underwent uncomplicated cataract extraction with intraocular lens implantation, presented 12 days later with acute pain, redness, and vision loss in her left eye. Visual acuity was hand motion and clinical findings suggested the diagnosis of acute postoperative endophthalmitis...
September 27, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28946177/surgical-intervention-for-pituitary-apoplexy-an-analysis-of-functional-outcomes
#10
Martin J Rutkowski, Sandeep Kunwar, Lewis Blevins, Manish K Aghi
OBJECTIVE Pituitary apoplexy is a clinical syndrome consisting of neurological and endocrine abnormalities secondary to hemorrhage or ischemia of an underlying pituitary adenoma. The authors investigated whether there was a significant difference in neurological, endocrine, and nonneuroendocrine outcomes for patients with pituitary apoplexy, based on the time between symptom onset and surgical intervention. METHODS The authors retrospectively analyzed the medical records of 32 patients who had presented to their institution with acute pituitary apoplexy and subsequently undergone endonasal transsphenoidal resection in the period from 2003 to 2014...
September 15, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28936911/postoperative-transient-blindness-after-general-anesthesia-and-surgery-case-report-of-conversion-disorder
#11
Semih Gungor, Rohit Aiyer
Postoperative acute visual loss due to organic pathology has been described after spinal surgery in the prone position. This report describes a case of transient postoperative blindness in a patient after general anesthesia and surgery in the prone position. Postoperative workup did not reveal any organic pathology. Unbeknown to the treating physicians, the patient had a comorbid untreated psychiatric history. Upon psychiatric consultation, the patient was diagnosed with conversion disorder as a cause of postoperative blindness...
September 2017: Pain Management
https://www.readbyqxmd.com/read/28934525/short-daytime-naps-briefly-attenuate-objectively-measured-sleepiness-under-chronic-sleep-restriction
#12
Jared M Saletin, Cassie J Hilditch, William C Dement, Mary A Carskadon
Study Objectives: Napping is a useful countermeasure to the negative effects of acute sleep loss on alertness. The efficacy of naps to recover from chronic sleep loss is less well understood. Methods: Following 2 baseline nights (10 hours' time-in-bed), participants were restricted to 7 nights of 5-hour sleep opportunity. Ten adults participated in the No-Nap condition, and a further 9 were assigned to a Nap condition with a daily 45-minute nap opportunity at 1300 h...
September 1, 2017: Sleep
https://www.readbyqxmd.com/read/28927429/the-impact-of-lipoprotein-lipase-deficiency-on-health-related-quality-of-life-a-detailed-structured-qualitative-study
#13
Sasi Neelamekam, See Kwok, Rachel Malone, Anthony S Wierzbicki, Handrean Soran
BACKGROUND: Lipoprotein lipase deficiency (LPLD) is an autosomal recessive inherited disorder caused by loss-of-function mutations in genes involved in the lipoprotein lipase pathway. It is characterised by chylomicronaemia, severe hypertriglyceridaemia and an increased risk of recurrent pancreatitis that often requires hospitalisation. This research aimed to improve our understanding of the debilitating impact that LPLD has on the daily lives of patients and their families. METHODS: The research comprised a 2-h interview with the patient and, where possible, a 1-h interview with a family member; a 1-week pre- and post-interview task (written and/or video diary); and a 30-45-min follow-up telephone interview...
September 19, 2017: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/28926646/vascular-hypoperfusion-in-acute-optic-neuritis-is-a-potentially-new-neurovascular-model-for-demyelinating-diseases
#14
Ta-Ching Chen, Chao-Yuan Yeh, Chao-Wen Lin, Chung-May Yang, Chang-Hao Yang, I-Hung Lin, Pao-Yang Chen, Jung-Yu Cheng, Fung-Rong Hu
PURPOSE: Optic neuritis is highly correlated with multiple sclerosis and is a major cause of acute visual loss and long-term neuronal degeneration. Primary cerebral hypoperfusion has been reported in brain demyelinating diseases. This study investigated whether peripapillary perfusion is changed in patients with acute optic neuritis (AON). METHODS: This three-year cohort study was conducted from September 1 2012, to August 31, 2015. Two hundred and forty-one patients with non-glaucomatous acute optic neuropathy were screened, and 42 non-highly myopic patients who had suffered their first episode of unilaterally idiopathic AON were studied...
2017: PloS One
https://www.readbyqxmd.com/read/28926381/total-elbow-arthroplasty-for-distal-humeral-fractures-a-ten-year-minimum-follow-up-study
#15
Raul Barco, Philipp N Streubel, Bernard F Morrey, Joaquin Sanchez-Sotelo
BACKGROUND: Total elbow arthroplasty is commonly considered for elderly patients with comminuted distal humeral fractures. Satisfactory short-term outcomes have been reported, but long-term outcomes are unknown. Our purpose was to assess the long-term outcomes of total elbow arthroplasty after distal humeral fracture and to determine differences between elbows with or without inflammatory arthritis at the time of fracture. METHODS: Forty-four total elbow arthroplasties were performed after distal humeral fracture; those patients were followed for a minimum of 10 years and were evaluated with regard to pain, motion, Mayo Elbow Performance Scores, complications, and reoperations...
September 20, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28924582/data-on-the-effect-of-conductive-hearing-loss-on-auditory-and-visual-cortex-activity-revealed-by-intrinsic-signal-imaging
#16
Manuel Teichert, Jürgen Bolz
This data article provides additional data related to the research article entitled "Simultaneous intrinsic signal imaging of auditory and visual cortex reveals profound effects of acute hearing loss on visual processing" (Teichert and Bolz, 2017) [1]. The primary auditory and visual cortex (A1 and V1) of adult male C57BL/6J mice (P120-P240) were mapped simultaneously using intrinsic signal imaging (Kalatsky and Stryker, 2003) [2]. A1 and V1 activity evoked by combined auditory and visual stimulation were measured before and after conductive hearing loss (CHL) induced by bilateral malleus removal...
October 2017: Data in Brief
https://www.readbyqxmd.com/read/28924446/use-of-intravitreal-dexamethasone-in-a-case-of-anterior-ischemic-optic-neuropathy
#17
Raffaele Nuzzi, Francesca Monteu
Nowadays there is no unique and well-established treatment for nonarteritic anterior ischemic optic neuropathy, despite being the main acute pathology that affects the optic nerve in the elderly population and often resulting in a significant loss of visual acuity. The effectiveness of oral steroids is still under debate in the international literature, although many studies show that patients treated with high doses of systemic corticosteroids have a significantly higher chance of improved visual acuity and visual fields...
May 2017: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/28882597/the-acute-and-chronic-effects-of-intravitreal-anti-vascular-endothelial-growth-factor-injections-on-intraocular-pressure-a-review
#18
REVIEW
Peter Bracha, Nicholas A Moore, Thomas A Ciulla, Darrell WuDunn, Louis B Cantor
The acute and chronic effects of repeated intravitreal anti-vascular endothelial growth factor (VEGF) injections on intraocular pressure (IOP) have not been fully characterized and the development of sustained ocular hypertension could adversely affect patients who are at risk of glaucomatous optic neuropathy. As expected, volume-driven, acute ocular hypertension immediately follows intravitreal injection, but this pressure elevation is generally transient and well-tolerated. Several medications have been investigated to limit acute ocular hypertension following anti-VEGF therapy, but the benefits of pretreatment are not conclusive...
September 4, 2017: Survey of Ophthalmology
https://www.readbyqxmd.com/read/28867757/visual-field-improvement-in-non-arteritic-posterior-ischemic-optic-neuropathy-in-a-patient-treated-with-intravenous-prostaglandin-e1-and-steroids
#19
Robert Davis Jr Steigerwalt, Paolo Giuseppe Limoli, Marcella Nebbioso
Non-arteritic posterior ischemic optic neuropathy (NA-PION) is a disorder of reduced blood flow to the retrobulbar optic nerve. There is usually an acute loss of visual acuity and field. Previous studies have noted an improvement in visual acuity and in ocular and retrobulbar blood flow with the use of a potent vasodilator of the microcirculation, prostaglandin E1 (PGE1), and steroids. The current report describes immediate improvement in the visual fields and visual acuity in a patient with NA-PION treated with intravenous PGE1 and steroids 66 hours after onset...
2017: Drug Discoveries & Therapeutics
https://www.readbyqxmd.com/read/28859531/hearing-disorder-from-music-a-neglected-dysfunction
#20
Annett Szibor, Petteri Hyvärinen, Jarmo Lehtimäki, Ulla Pirvola, Matti Ylikoski, Antti Mäkitie, Antti Aarnisalo, Jukka Ylikoski
CONCLUSION: Music-induced acute acoustic trauma is not inevitably linked to hearing dysfunction as validated by conventional pure tone audiometry. Tinnitus is often in combination with hyperacusis. Our results point at 'silent hearing loss' as the underlying pathology, having afferent nerve terminal damage rather than hair cell loss as the structural correlate. OBJECTIVES: Exposure to loud music is one of the most common causes of acute acoustic trauma, which adolescents and teenagers experience by voluntary exposure to loud music of sound levels up to 110 dB(A)...
August 31, 2017: Acta Oto-laryngologica
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