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Chronic fatigue syndrome

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https://www.readbyqxmd.com/read/29154201/neuroendocrine-disorder-in-chronic-fatigue-syndrome
#1
Slavica Tomic, Snezana Brkic, Dajana Lendak, Daniela Maric, Milica Medic Stojanoska, Aleksandra Novakov Mikic
Background/aim: Neuroendocrine disorders are considered a possible pathogenetic mechanism in chronic fatigue syndrome (CFS). The aim of our study was to determine the function of the hypothalamic-pituitary-adrenal axis (HPA) and thyroid function in women of reproductive age suffering from CFS. Materials and methods: The study included 40 women suffering from CFS and 40 healthy women (15-45 years old). Serum levels of cortisol (0800 and 1800 hours), ACTH, total T4, total T3, and TSH were measured in all subjects...
August 23, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/29152994/decreased-connectivity-and-increased-bold-complexity-in-the-default-mode-network-in-individuals-with-chronic-fatigue-syndrome
#2
Zack Y Shan, Kevin Finegan, Sandeep Bhuta, Timothy Ireland, Donald R Staines, Sonya M Marshall-Gradisnik, Leighton R Barnden
The chronic fatigue syndrome / myalgic encephalomyelitis (CFS) is a debilitating disease with unknown pathophysiology and no diagnostic test. This study investigated the default mode network (DMN) in order to understand the pathophysiology of CFS and to identify potential biomarkers. Using functional MRI (fMRI) collected from 72 subjects (45 CFS and 27 controls) with a temporal resolution of 0.798s, we evaluated the default mode network using static functional connectivity (FC), dynamic functional connectivity (DFC) and DFC complexity, blood oxygenation level dependent (BOLD) activation maps and complexity of activity...
November 20, 2017: Brain Connectivity
https://www.readbyqxmd.com/read/29133662/a-tiny-tick-can-cause-a-big-health-problem
#3
Manuel John, M Raman, Keith Ryan
Ticks are tiny crawling bugs in the spider family that feed by sucking blood from animals. They are second only to mosquitoes as vectors of human disease, both infectious and toxic. Infected ticks spread over a hundred diseases, some of which are fatal if undetected. They spread the spirochete (which multiplies in the insect's gut) with a subsequent bite to the next host. We describe the only reported cases of peri ocular tick bite from India that presented to us within a span of 3 days and its management. Due suspicion and magnification of the lesions revealed the ticks which otherwise masqueraded as small skin tags/moles on gross examination...
November 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29133321/can-physical-assessment-techniques-aid-diagnosis-in-people-with-chronic-fatigue-syndrome-myalgic-encephalomyelitis-a-diagnostic-accuracy-study
#4
Lucy Hives, Alice Bradley, Jim Richards, Chris Sutton, James Selfe, Bhaskar Basu, Kerry Maguire, Gail Sumner, Tarek Gaber, Annice Mukherjee, Raymond N Perrin
OBJECTIVE: To assess five physical signs to see whether they can assist in the screening of patients with chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) and potentially lead to quicker treatment. METHODS: This was a diagnostic accuracy study with inter-rater agreement assessment. Participants recruited from two National Health Service hospitals, local CFS/ME support groups and the community were examined by three practitioners on the same day in a randomised order...
November 13, 2017: BMJ Open
https://www.readbyqxmd.com/read/29127316/exercise-induced-changes-in-cerebrospinal-fluid-mirnas-in-gulf-war-illness-chronic-fatigue-syndrome-and-sedentary-control-subjects
#5
James N Baraniuk, Narayan Shivapurkar
Gulf War Illness (GWI) and Chronic Fatigue Syndrome (CFS) have similar profiles of pain, fatigue, cognitive dysfunction and exertional exhaustion. Post-exertional malaise suggests exercise alters central nervous system functions. Lumbar punctures were performed in GWI, CFS and control subjects after (i) overnight rest (nonexercise) or (ii) submaximal bicycle exercise. Exercise induced postural tachycardia in one third of GWI subjects (Stress Test Activated Reversible Tachycardia, START). The remainder were Stress Test Originated Phantom Perception (STOPP) subjects...
November 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29118054/vitamin-d-status-in-chronic-fatigue-syndrome-myalgic-encephalomyelitis-a-cohort-study-from-the-north-west-of-england
#6
Kate E Earl, Giorgos K Sakellariou, Melanie Sinclair, Manuel Fenech, Fiona Croden, Daniel J Owens, Jonathan Tang, Alastair Miller, Clare Lawton, Louise Dye, Graeme L Close, William D Fraser, Anne McArdle, Michael B J Beadsworth
OBJECTIVE: Severe vitamin D deficiency is a recognised cause of skeletal muscle fatigue and myopathy. The aim of this study was to examine whether chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) is associated with altered circulating vitamin D metabolites. DESIGN: Cohort study. SETTING: UK university hospital, recruiting from April 2014 to April 2015. PARTICIPANTS: Ninety-two patients with CFS/ME and 94 age-matched healthy controls (HCs)...
November 8, 2017: BMJ Open
https://www.readbyqxmd.com/read/29111893/-psychological-health-of-children-with-chronic-physical-illness-and-their-parents-results-from-meta-analyses
#7
Martin Pinquart
Psychological Health of Children with Chronic Physical Illness and their Parents - Results from Meta-Analyses The present paper summarizes results from meta-analyses on psychological well-being of children with chronic physical illnesses and their parents. At the beginning, we discuss potential reasons for psychological effects of a chronic physical illness on children and adolescents as well as their parents. We then summarize results of meta-analyses of studies that compared aspects of mental health of children with a chronic physical illness and their parents with families of healthy children...
November 2017: Praxis der Kinderpsychologie und Kinderpsychiatrie
https://www.readbyqxmd.com/read/29104961/a-comparison-of-case-definitions-for-myalgic-encephalomyelitis-and-chronic-fatigue-syndrome
#8
Madison Sunnquist, Leonard A Jason, Pamela Nehrke, Ellen M Goudsmit
Many professionals have described the clinical presentation of myalgic encephalomyelitis (ME), but recent efforts have focused on the development of ME criteria that can be reliably applied. The current study compared the symptoms and functioning of individuals who met the newly-developed Institute of Medicine (IOM) clinical criteria to a revised version of the London criteria for ME. While 76% of a sample diagnosed with chronic fatigue syndrome (CFS) met the IOM criteria, 44% met the revised London criteria...
2017: J Chronic Dis Manag
https://www.readbyqxmd.com/read/29102461/effect-of-swarna-jibanti-coelogyne-cristata-lindley-in-alleviation-of-chronic-fatigue-syndrome-in-aged-wistar-rats
#9
Achintya Mitra, Tapas Kumar Sur, Sachhidananda Upadhyay, Dipankar Bhattacharyya, Jayram Hazra
BACKGROUND: Swarna Jibanti scientifically known as Coelogyne cristata Lindley (Orchidaceae), an orchid mentioned in Ayurvedic medicine is used to promote healthy life span. OBJECTIVE: The present work was planned to study the efficacy of hydro-alcoholic extract of pseudobulbs of C.cristata (CCE) to assess its role on chronic fatigue syndrome (CFS) induced behavioural and biochemical changes in aged Wistar rats compared to Panax ginseng (PG), a prototype anti-stress agent...
November 1, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/29099955/screening-for-adult-adhd-in-patients-with-fibromyalgia-syndrome
#10
Roland van Rensburg, Helgard Pieter Meyer, Sonia Anne Hitchcock, Christian Edward Schuler
Objective: Fibromyalgia syndrome (FMS) is a common chronic pain disorder associated with altered activity of neurotransmitters involved in pain sensitivity such as dopamine, serotonin, and noradrenaline. FMS may significantly impact an individual's functioning due to the presence of chronic pain, fatigue, and cognitive impairment. Dyscognition may be more disabling than the chronic pain but is mostly under-recognized. This study aimed to assess the potential co-occurrence of FMS and adult attention deficit hyperactivity disorder (ADHD), a chronic neurodevelopmental disorder also associated with impaired cognition and dopaminergic function...
November 1, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/29099864/assessing-olfactory-functions-in-patients-with-barth-syndrome
#11
Michele Dibattista, Simona Lobasso, Sebastiano Stramaglia, Angela Corcelli
Barth syndrome is a rare X-linked disease affecting less than 200 individuals worldwide. Several comorbidities have been associated with the pathology and, among those, cardiac myopathy and neutropenia are the most life threatening. The appropriate nutritive support is important to sustain the everyday life of Barth syndrome patients given the chronic fatigue they experience. Since they often prefer salty and fried food, and avoid vegetables and fruits, their eating habit and food preferences do not always provide the proper amount of vitamins and amino acids...
2017: PloS One
https://www.readbyqxmd.com/read/29097315/mapping-of-thalamic-magnetic-susceptibility-in-multiple-sclerosis-indicates-decreasing-iron-with-disease-duration-a-proposed-mechanistic-relationship-between-inflammation-and-oligodendrocyte-vitality
#12
Ferdinand Schweser, Ana Luiza Raffaini Duarte Martins, Jesper Hagemeier, Fuchun Lin, Jannis Hanspach, Bianca Weinstock-Guttman, Simon Hametner, Niels P Bergsland, Michael G Dwyer, Robert Zivadinov
Recent advances in susceptibility MRI have dramatically improved the visualization of deep gray matter brain regions and the quantification of their magnetic properties in vivo, providing a novel tool to study the poorly understood iron homeostasis in the human brain. In this study, we used an advanced combination of the recent quantitative susceptibility mapping technique with dedicated analysis methods to study intra-thalamic tissue alterations in patients with clinically isolated syndrome (CIS) and multiple sclerosis (MS)...
October 30, 2017: NeuroImage
https://www.readbyqxmd.com/read/29096528/the-presence-of-co-morbid-mental-health-problems-in-a-cohort-of-adolescents-with-chronic-fatigue-syndrome
#13
Maria Elizabeth Loades, Katharine A Rimes, Sheila Ali, Kate Lievesley, Trudie Chalder
OBJECTIVE: To report on the prevalence of mental health disorders in adolescents with chronic fatigue syndrome (CFS) and to compare the diagnoses identified by a brief clinician-administered psychiatric interview with self-report screening questionnaires. DESIGN: Cross-sectional study. SETTING: Consecutive attenders to specialist CFS clinics in the United Kingdom. PATIENTS: N = 52 adolescents, age 12-18 years with CFS...
October 1, 2017: Clinical Child Psychology and Psychiatry
https://www.readbyqxmd.com/read/29079320/cognitive-dysfunction-associated-with-aluminum-hydroxide-induced-macrophagic-myofasciitis-a-reappraisal-of-neuropsychological-profile
#14
Mehdi Aoun Sebaiti, Paul Kauv, Anaïs Charles-Nelson, Axel Van Der Gucht, Paul Blanc-Durand, Emmanuel Itti, Romain K Gherardi, Anne-Catherine Bachoud-Levi, François Jérôme Authier
Patients with macrophagic myofasciitis (MMF) present with diffuse arthromyalgias, chronic fatigue, and cognitive disorder. Representative features of MMF-associated cognitive dysfunction include attentional dysfunction, dysexecutive syndrome, visual memory deficit and left ear extinction. Our study aims to reevaluate the neuropsychological profile of MMF. 105 unselected consecutive MMF patients were subjected to a neuropsychological battery of screen short term and long-term memory, executive functions, attentional abilities, instrumental functions and dichotic listening...
October 6, 2017: Journal of Inorganic Biochemistry
https://www.readbyqxmd.com/read/29071982/-effect-of-acupuncture-on-the-expression-of-transcription-factor-t-bet-gata-3-in-plasma-of-rats-with-chronic-fatigue-syndrome
#15
Xiang-Yi Wang, Chang-Zheng Liu, Bo Lei
OBJECTIVE: To observe the effect of acupuncture on the expression of T-box expressed in T cell (T-bet)/GATA binding factor-3 (GATA-3) in plasma of rats with chronic fatigue syndrome (CFS) and explore the mechanism of acupuncture treatment for CFS. METHODS: Forty-eight healthy male SD rats were randomly divided into blank control group, CFS model group, acupuncture group, and ginsenoside group (12 rats in each group). CFS rat model was established by combining restriction and cold water swimming...
June 25, 2017: Zhen Ci Yan Jiu, Acupuncture Research
https://www.readbyqxmd.com/read/29068997/atypical-hemolytic-uremic-syndrome-induced-by-cblc-subtype-of-methylmalonic-academia-a-case-report-and-literature-review
#16
REVIEW
Minguang Chen, Jieqiu Zhuang, JianHuan Yang, Dexuan Wang, Qing Yang
RATIONALE: Methylmalonic acidemia (MMA) is a common organic acidemia, mainly due to methylmalonyl-CoA mutase (MCM) or its coenzyme cobalamin (VitB12) metabolic disorders. Cobalamin C (CblC) type is the most frequent inborn error of cobalamin metabolism; it can develop symptoms in childhood and often combine multisystem damage, which leads to methylmalonic acid, propionic acid, methyl citrate, and other metabolites abnormal accumulation, causing nerve, liver, kidney, bone marrow, and other organ damage...
October 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29065167/cellular-bioenergetics-is-impaired-in-patients-with-chronic-fatigue-syndrome
#17
Cara Tomas, Audrey Brown, Victoria Strassheim, Joanna Elson, Julia Newton, Philip Manning
Chronic fatigue syndrome (CFS) is a highly debilitating disease of unknown aetiology. Abnormalities in bioenergetic function have been cited as one possible cause for CFS. Preliminary studies were performed to investigate cellular bioenergetic abnormalities in CFS patients. A series of assays were conducted using peripheral blood mononuclear cells (PBMCs) from CFS patients and healthy controls. These experiments investigated cellular patterns in oxidative phosphorylation (OXPHOS) and glycolysis. Results showed consistently lower measures of OXPHOS parameters in PBMCs taken from CFS patients compared with healthy controls...
2017: PloS One
https://www.readbyqxmd.com/read/29062593/clinical-criteria-versus-a-possible-research-case-definition-in-chronic-fatigue-syndrome-myalgic-encephalomyelitis
#18
Leonard A Jason, Stephanie McManimen, Madison Sunnquist, Julia L Newton, Elin Bolle Strand
BACKGROUND: The Institute of Medicine (IOM) recently developed clinical criteria for what had been known as chronic fatigue syndrome (CFS). Given the broad nature of the clinical IOM criteria, there is a need for a research definition that would select a more homogenous and impaired group of patients than the IOM clinical criteria. At the present time, it is unclear what will serve as the research definition. PURPOSE: The current study focused on a research definition which selected homebound individuals who met the four IOM criteria, excluding medical and psychiatric co-morbidities...
2017: Fatigue: Biomedicine, Health and Behavior
https://www.readbyqxmd.com/read/29061232/reports-of-postural-orthostatic-tachycardia-syndrome-after-human-papillomavirus-vaccination-in-the-vaccine-adverse-event-reporting-system
#19
Jorge Arana, Adamma Mba-Jonas, Christopher Jankosky, Paige Lewis, Pedro L Moro, Tom T Shimabukuro, Maria Cano
PURPOSE: Human papillomavirus (HPV) vaccination prevents infections with HPV strains that cause certain cancers. Reports of postural orthostatic tachycardia syndrome (POTS) following HPV vaccination have raised safety concerns. We reviewed POTS reports submitted to the Vaccine Adverse Event Reporting System (VAERS). METHODS: We searched the VAERS database for reports of POTS following any type of HPV vaccination (bivalent, quadrivalent, or nonavalent) from June 2006 to August 2015...
November 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/29060408/features-selection-for-bayes-classification-of-prolonged-fatigue-on-rectus-femoris-muscle
#20
Fauzani N Jamaluddin, Siti A Ahmad, Samsul Bahari Mohd Noor, Wan Zuha Wan Hassan, Y Azhar
Sports training is very important to athletes in improving and maintaining their performances. It commonly involves high intensity exercise and requires longer time for fatigue to recover, compares to normal activity. During training, adequate rest is essential to allow recuperation and build body strength. Unfortunately, inadequate rest exposes the body to prolonged fatigue (PF). Hence, this condition needs to be managed accordingly to avoid chronic fatigue syndrome. Recent findings indicate that there are strong characteristics on surface EMG under PF conditions...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
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