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Chronic fatigue syndrome

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https://www.readbyqxmd.com/read/28535557/endogenous-pain-facilitation-rather-than-inhibition-differs-between-people-with-chronic-fatigue-syndrome-multiple-sclerosis-and-controls-an-observational-study
#1
Simon M Collin, Jo Nijs, Mira Meeus, Andrea Polli, Barbara Willekens, Kelly Ickmans
BACKGROUND: Commonalities in the core symptoms of fatigue and cognitive dysfunction experienced by chronic fatigue syndrome (CFS, also known as ME) and multiple sclerosis (MS) patients have been described. Many CFS and MS patients also experience chronic pain, which has been attributed to central sensitization in both groups of patients. However, the characteristics of pain in CFS and MS patients have not been compared. OBJECTIVES: To compare experimental pain measurements in patients with CFS or MS and healthy controls...
May 2017: Pain Physician
https://www.readbyqxmd.com/read/28535163/re-multi-site-clinical-assessment-of-myalgic-encephalomyelitis-chronic-fatigue-syndrome-mcam-design-and-implementation-of-a-prospective-retrospective-rolling-cohort-study
#2
(no author information available yet)
No abstract text is available yet for this article.
May 22, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28516431/a-comparison-of-neuroimaging-abnormalities-in-multiple-sclerosis-major-depression-and-chronic-fatigue-syndrome-myalgic-encephalomyelitis-is-there-a-common-cause
#3
REVIEW
Gerwyn Morris, Michael Berk, Basant K Puri
There is copious evidence of abnormalities in resting-state functional network connectivity states, grey and white matter pathology and impaired cerebral perfusion in patients afforded a diagnosis of multiple sclerosis, major depression or chronic fatigue syndrome (CFS) (myalgic encephalomyelitis). Systemic inflammation may well be a major element explaining such findings. Inter-patient and inter-illness variations in neuroimaging findings may arise at least in part from regional genetic, epigenetic and environmental variations in the functions of microglia and astrocytes...
May 17, 2017: Molecular Neurobiology
https://www.readbyqxmd.com/read/28505018/the-variation-of-the-5-hydroxytryptamine-system-between-chronic-unpredictable-mild-stress-rats-and-chronic-fatigue-syndrome-rats-induced-by-forced-treadmill-running
#4
Yin Cao, Qinglin Li
The aim of this study was to observe the variation in the 5-hydroxytryptamine (5-HT) system between a chronic unpredictable mild stress (CUMS) model and a chronic fatigue syndrome (CFS) model. The total distance, the crossing pieces, and rearing times in the open-field test of the CUMS group and the CFS group were all less than those of the control group to different degrees. The concentrations of tryptophan, 5-HT, and 5-HIAA of the CUMS group were obviously lower than those of the control group. In the CFS model, the concentrations of tryptophan, 5-HT, and 5-HIAA were obviously higher than those of the control group...
May 12, 2017: Neuroreport
https://www.readbyqxmd.com/read/28500690/tnf-receptor-associated-periodic-syndrome-traps-mimicking-chronic-spontaneous-urticaria
#5
S Aurich, J C Simon, R Treudler
Tumor necrosis factor (TNF) receptor-associated periodic syndrome (TRAPS) is a rare (about one per million) autosomal dominant autoinflammatory disease being typically characterized by recurrent fever episodes accompanied by variable gastrointestinal, musculoskeletal, neurological, lymphoid, urogenital and skin symptoms (table 1) [1-3]. We report on a 21 year old non atopic male with prediagnosed IgA deficiency, Marfan syndrome and hypothyroidism who first presented in our university allergy centre with three year history of antihistamine resistant, only slightly itching urticarial rash being accompanied by fatigue...
May 13, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28495811/randomised-controlled-trial-of-online-continuing-education-for-health-professionals-to-improve-the-management-of-chronic-fatigue-syndrome-a-study-protocol
#6
Sophie H Li, Carolina X Sandler, Sally M Casson, Joanne Cassar, Tina Bogg, Andrew R Lloyd, Benjamin K Barry
INTRODUCTION: Chronic fatigue syndrome (CFS) is a serious and debilitating illness that affects between 0.2%-2.6% of the world's population. Although there is level 1 evidence of the benefit of cognitive behaviour therapy (CBT) and graded exercise therapy (GET) for some people with CFS, uptake of these interventions is low or at best untimely. This can be partly attributed to poor clinician awareness and knowledge of CFS and related CBT and GET interventions. This trial aims to evaluate the effect of participation in an online education programme, compared with a wait-list control group, on allied health professionals' knowledge about evidence-based CFS interventions and their levels of confidence to engage in the dissemination of these interventions...
May 10, 2017: BMJ Open
https://www.readbyqxmd.com/read/28494812/whole-blood-gene-expression-in-adolescent-chronic-fatigue-syndrome-an-exploratory-cross-sectional-study-suggesting-altered-b-cell-differentiation-and-survival
#7
Chinh Bkrong Nguyen, Lene Alsøe, Jessica M Lindvall, Dag Sulheim, Even Fagermoen, Anette Winger, Mari Kaarbø, Hilde Nilsen, Vegard Bruun Wyller
BACKGROUND: Chronic fatigue syndrome (CFS) is a prevalent and disabling condition affecting adolescents. The pathophysiology is poorly understood, but immune alterations might be an important component. This study compared whole blood gene expression in adolescent CFS patients and healthy controls, and explored associations between gene expression and neuroendocrine markers, immune markers and clinical markers within the CFS group. METHODS: CFS patients (12-18 years old) were recruited nation-wide to a single referral center as part of the NorCAPITAL project...
May 11, 2017: Journal of Translational Medicine
https://www.readbyqxmd.com/read/28490352/a-diagnostic-biomarker-profile-for-fibromyalgia-syndrome-based-on-an-nmr-metabolomics-study-of-selected-patients-and-controls
#8
Bontle G Malatji, Helgard Meyer, Shayne Mason, Udo F H Engelke, Ron A Wevers, Mari van Reenen, Carolus J Reinecke
BACKGROUND: Fibromyalgia syndrome (FMS) is a chronic pain syndrome. A plausible pathogenesis of the disease is uncertain and the pursuit of measurable biomarkers for objective identification of affected individuals is a continuing endeavour in FMS research. Our objective was to perform an explorative metabolomics study (1) to elucidate the global urinary metabolite profile of patients suffering from FMS, and (2) to explore the potential of this metabolite information to augment existing medical practice in diagnosing the disease...
May 11, 2017: BMC Neurology
https://www.readbyqxmd.com/read/28480859/the-effects-of-non-functional-overreaching-and-overtraining-on-autonomic-nervous-system-function-in-highly-trained-athletes
#9
T Kajaia, L Maskhulia, K Chelidze, V Akhalkatsi, Z Kakhabrishvili
Aim of the study was to compare the ANS functioning, as measured by heart rate variability (HRV), in athletes with non-functional overreaching (NFO) and overtraining syndrome (OTS) and in athletes without NFO/OTS. In 43 athletes with NFO/OTS, 40 athletes without NFO/OTS, as well as in 35 sedentary subjects the ANS function was evaluated with the Autonomic Balance Test, based on the HRV analysis of resting heart rate recordings. Results of the study show lower HRV and lower vagal influence along with increased sympathetic cardiovascular control in athletes with non-functional overreaching and particularly in athletes with overtraining, than in highly trained athletes without NFO/OTS...
March 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28478837/the-spread-of-ebv-to-ectopic-lymphoid-aggregates-may-be-the-final-common-pathway-in-the-pathogenesis-of-me-cfs
#10
Willy Eriksen
According to the hypothesis presented here, myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) develops over 3 steps: Step 1 is characterized by the aggregation of lymphoid cells in dorsal root ganglia or other nervous structures. The cause of this formation of ectopic lymphoid aggregates may be an acute infection, asymptomatic reactivations of a common neurotropic virus, exposure to a neurotoxin, or physical injury to peripheral nerves. In step 2, Epstein-Barr virus (EBV)-infected lymphocytes or monocytes bring EBV from the circulation to one or several of these lymphoid aggregates, whereupon cell-to-cell transmission of EBV and proliferation of latently EBV-infected lymphocytes lead to the presence of many EBV-infected cells in the lymphoid aggregates...
May 2017: Medical Hypotheses
https://www.readbyqxmd.com/read/28476513/animal-models-of-cachexia-and-sarcopenia-in-chronic-illness-cardiac-function-body-composition-changes-and-therapeutic-results
#11
REVIEW
Junichi Ishida, Masakazu Saitoh, Wolfram Doehner, Stephan von Haehling, Markus Anker, Stefan D Anker, Jochen Springer
Cachexia is defined as a complex metabolic syndrome associated with underlying illness that is characterized by the loss of body weight consisting of muscle and fat mass wasting. Sarcopenia is defined as the ageing related loss of muscle mass in health and disease that may not have an effect on body weight. As millions of patients are in cachectic or sarcopenic states, both conditions contribute to high numbers to death worldwide. A number of treatments have been proposed for cachexia and sarcopenia, but these are either in the preclinical stage or in clinical trials and hence not available to the general population...
April 2, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28476151/health-care-resource-use-by-patients-before-and-after-a-diagnosis-of-chronic-fatigue-syndrome-cfs-me-a-clinical-practice-research-datalink-study
#12
Simon M Collin, Inger J Bakken, Irwin Nazareth, Esther Crawley, Peter D White
BACKGROUND: Our aim was to investigate patterns of health care resource use by patients before and after a diagnosis of CFS/ME, as recorded by Clinical Practice Research Datalink (CPRD) GP practices in the UK. METHODS: We used a case-control study design in which patients who had a first recorded diagnosis of CFS/ME during the period 01/01/2001 to 31/12/2013 were matched 1:1 with controls by age, sex, and GP practice. We compared rates of GP consultations, diagnostic tests, prescriptions, referrals, and symptoms between the two groups from 15 years (in adults) or 10 years (in children) before diagnosis to 10 years after diagnosis...
May 5, 2017: BMC Family Practice
https://www.readbyqxmd.com/read/28473005/guided-self-help-for-patients-with-chronic-fatigue-syndrome-prior-to-starting-cognitive-behavioural-therapy-a-cohort-study
#13
Sheila Ali, Kimberley Goldsmith, Mary Burgess, Trudie Chalder
BACKGROUND: Previous research suggests that minimal interventions such as self-help guidance can improve outcomes in patients with fatigue or chronic fatigue syndrome (CFS). AIMS: The aim of the current study was to investigate whether self-help guidance could improve physical functioning, social adjustment and fatigue in a group of patients with CFS who were awaiting CBT at a clinic in secondary care. METHOD: Patients completed questionnaires at their initial assessment (baseline), immediately before beginning CBT (pre-treatment), and after their last session of CBT (end of treatment)...
May 5, 2017: Behavioural and Cognitive Psychotherapy
https://www.readbyqxmd.com/read/28470767/sleep-wake-rhythm-disturbances-and-perceived-sleep-in-adolescent-chronic-fatigue-syndrome
#14
Maria Pedersen, Mirjam Ekstedt, Milada C Småstuen, Vegard B Wyller, Dag Sulheim, Even Fagermoen, Anette Winger, Edvard Pedersen, Harald Hrubos-Strøm
Chronic fatigue syndrome (CFS) is characterized by long-lasting, disabling and unexplained fatigue that is often accompanied by unrefreshing sleep. The aim of this cross-sectional study was to investigate sleep-wake rhythm and perceived sleep in adolescent CFS patients compared to healthy individuals. We analysed baseline data on 120 adolescent CFS patients and 39 healthy individuals included in the NorCAPITAL project. Activity measures from a uniaxial accelerometer (activPAL) were used to estimate mid-sleep time (mid-point of a period with sleep) and time in bed...
May 4, 2017: Journal of Sleep Research
https://www.readbyqxmd.com/read/28463341/expression-of-concern-adaptive-pacing-cognitive-behaviour-therapy-graded-exercise-and-specialist-medical-care-for-chronic-fatigue-syndrome-a-cost-effectiveness-analysis
#15
https://www.readbyqxmd.com/read/28461987/fatigue-depression-and-quality-of-life-in-patients-with-prostatic-diseases
#16
Tobias Engl, Daniela Drescher, Ralf Bickeböller, Ralph Grabhorn
INTRODUCTION: Fatigue and depression are commonly attributed to malignant and chronic benign diseases. However, these phenomena have been little investigated to date in prostatic diseases. Our aim was to compare fatigue and depression in prostate cancer patients treated with Androgen Deprivation Therapy (ADT) and in patients with Lower Urinary Tract Symptoms (LUTS) / Benign Prostatic Syndrome. MATERIAL AND METHODS: 100 patients each with PCa (prostate cancer) and BPS (Benign Prostatic Syndrome) were surveyed using the Brief Fatigue Inventory (BFI), EORTC-QLQ C30 [1], and Beck Depression Inventory (BDI)...
2017: Central European Journal of Urology
https://www.readbyqxmd.com/read/28459248/frontline-temporomandibular-joint-orofacial-pain-therapy-for-every-dental-practice
#17
Lisa Germain, Louis Malcmacher
Temporomandibular disorders (TMD) are a group of conditions affecting the temporomandibular joint and/or muscles of mastication. TMD may present along with many comorbid pain syndromes such as myofascial pain, headache, and neck and back stiffness with limited range of motion, as well as fibromyalgia and chronic fatigue syndrome. The diagnosis and management of TMD is complex and, many times, multidisciplinary. However, dentists can provide their patients with frontline temporomandibular/orofacial pain therapy with didactic and hands-on training that provides a better understanding and a conservative approach for treatment of TMDs...
May 2017: Compendium of Continuing Education in Dentistry
https://www.readbyqxmd.com/read/28458530/frailty-syndrome-in-ambulatory-patients-with-copd
#18
Panita Limpawattana, Siraphong Putraveephong, Pratchaya Inthasuwan, Watchara Boonsawat, Daris Theerakulpisut, Jarin Chindaprasirt
Frailty is a state of increased risk of unfavorable outcomes when exposed to stressors, and COPD is one of the several chronic illnesses associated with the condition. However, few studies have been conducted regarding the prevalence of COPD and its related factors in Southeast Asia. The objectives of this study were to determine the prevalence of frailty in COPD patients and to identify the associated factors in these populations. A cross-sectional study of COPD patients who attended a COPD clinic was conducted from May 2015 to December 2016...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/28453534/vitamin-and-mineral-status-in-chronic-fatigue-syndrome-and-fibromyalgia-syndrome-a-systematic-review-and-meta-analysis
#19
Monica L Joustra, Isidor Minovic, Karin A M Janssens, Stephan J L Bakker, Judith G M Rosmalen
BACKGROUND: Many chronic fatigue syndrome (CFS) and fibromyalgia syndrome (FMS) patients (35-68%) use nutritional supplements, while it is unclear whether deficiencies in vitamins and minerals contribute to symptoms in these patients. Objectives were (1) to determine vitamin and mineral status in CFS and FMS patients as compared to healthy controls; (2) to investigate the association between vitamin and mineral status and clinical parameters, including symptom severity and quality of life; and (3) to determine the effect of supplementation on clinical parameters...
2017: PloS One
https://www.readbyqxmd.com/read/28447135/-environmental-medical-syndromes
#20
REVIEW
Gerhard A Wiesmüller, Claudia Hornberg
Environmental medical syndromes comprise sick building syndrome (SBS), multiple chemical sensitivity (MCS)/idiopathic environmental intolerances (IEI), electromagnetic hypersensitivity, chronic fatigue syndrome (CFS), burnout, fibromyalgia, and the candida syndrome. There is also some overlap described in the literature. There is still no established knowledge of etiology, pathology, pathophysiology, diagnostics, therapy, prevention and prognosis. These syndromes are thought to result from a complex interaction of physical, chemical and/or (micro)biological environmental stresses, individual dispositions, psychological influencing factors, perceptual and processing processes, variants of somatization disorders, culturally or socially caused distress, or simply iatrogenic causation...
April 26, 2017: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
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