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https://www.readbyqxmd.com/read/28339927/characterizing-the-early-inflammatory-contribution-of-the-donor-kidney-following-reperfusion
#1
John P Stone, Muna Mohamud, Kavit Amin, William R Critchley, Rebecca J Edge, Marc J Clancy, Alexandra L Ball, James E Fildes
Background.: Donor kidneys contain a large reservoir of passenger leucocytes that contribute to acute rejection via direct alloantigen presentation and pro-inflammatory cytokine secretion. However, the early contribution of these cells following revascularization has not previously been described. We performed a secondary, high-volume preservation flush following cold storage to characterize the inflammatory contribution of the donor kidney upon reperfusion. Methods.: Porcine kidneys were retrieved using a protocol analogous to current UK clinical practice...
February 27, 2017: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/28338351/worldwide-impact-of-warmer-seasons-on-the-on-the-incidence-of-renal-colic-and-kidney-stone-disease-ksd-evidence-from-a-systematic-review-of-literature
#2
Robert Geraghty, Silvia Proietti, Olivier Traxer, Matthew Archer, Bhaskar K Somani
INTRODUCTION: Several studies have examined the link between temperature or monthly-seasonal variations and urolithiasis. The majority of these studies have demonstrated a link between higher ambient monthly temperatures and the incidence of renal colic and kidney stone disease (KSD). However a worldwide trend on this association has not been explored and we perform a systematic review to examine the effect of seasonal variations on renal colic and KSD. MATERIALS AND METHODS: A systematic review of literature over a 26-year period (1990-2017) was conducted on all studies reporting on the effect of seasonal variations and its link to KSD...
March 24, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/28338309/impact-of-personalized-three-dimensional-3d-printed-pelvicalyceal-system-models-on-patient-information-in-percutaneous-nephrolithotripsy-surgery-a-pilot-study
#3
Hasan Anil Atalay, H Lütfi Canat, Volkan Ülker, İlter Alkan, Ünsal Özkuvanci, Fatih Altunrende
OBJECTIVE: To investigate the impact of personalized three dimensional (3D) printed pelvicalyceal system models on patient information before percutaneous nephrolithotripsy surgery. MATERIAL AND METHODS: Patients with unilateral complex renal stones with indicatation of percutaneous nephrolithotripsy surgery were selected. Usable data of patients were obtained from CT scans as Digital Imaging and Communications in Medicine (DICOM) format. Mimics software version 16...
March 24, 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/28338301/analgesia-for-patients-undergoing-shockwave-lithotripsy-for-urinary-stones-a-systematic-review-and-meta-analysis
#4
Omar M Aboumarzouk, Rami Hasan, Ali Tasleem, Martin Mariappan, Rachael Hutton, John Fitzpatrick, Laura Beatty, Gareth E Jones, Tarik Amer
BACKGROUND: Shock wave lithotripsy (SWL) is the first line treatment modality for a significant proportion of patients with upper urinary tracts stones. Simple analgesics, opioids and non-steroidal anti-inflammatory drugs (NSAIDs) are all suitable agents but the relative efficacy and tolerability of these agents is uncertain. OBJECTIVES: To determine the efficacy of the different types of analgesics used for the control of pain during SWL for urinary stones. MATERIALS AND METHODS: We searched the Cochrane Renal Group's Specialised Register, MEDLINE, EMBASE and also hand-searched reference lists of relevant articles (Figure-1)...
March 24, 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/28336220/ureteroscopy-and-laser-stone-fragmentation-ursl-for-large-%C3%A2-1%C3%A2-cm-paediatric-stones-outcomes-from-a-university-teaching-hospital
#5
N C Featherstone, B K Somani, S J Griffin
INTRODUCTION: The treatment of large renal stones (≥1 cm) in paediatric patients is challenging. The usual treatment options include percutaneous nephrolithotomy (PCNL) or shockwave lithotripsy (SWL). There is a rise in the use of ureteroscopy and laser stone fragmentation (URSL) for paediatric stones; however, outcomes of treatment for large renal stones in this age group are still largely unknown. OBJECTIVE: To investigate the outcome of URSL for large paediatric renal stones ≥1 cm treated at the present institution over the last 5 years...
August 24, 2016: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28336203/is-extracorporeal-shock-wave-lithotripsy-a-current-treatment-for-urolithiasis-a-systematic-review
#6
P Bahílo Mateu, A Budía Alba, E Liatsikos, M Trassierra Villa, J D López-Acón, D de Guzmán Ordaz, F Boronat Tormo
INTRODUCTION: Technological advances have prompted a change in the management of urolithiasis. Endourological techniques are gaining importance because they are highly effective treatments. The aim of this study was to answer the question of whether extracorporeal shock wave lithotripsy (ESWL) is still a competitive alternative compared with other therapeutic modalities. ACQUISITION OF EVIDENCE: We conducted a literature search of articles published in the past 5 years...
March 20, 2017: Actas Urologicas Españolas
https://www.readbyqxmd.com/read/28336050/mortality-risk-disparities-in-children-receiving-chronic-renal-replacement-therapy-for-the-treatment-of-end-stage-renal-disease-across-europe-an-espn-era-edta-registry-analysis
#7
Nicholas C Chesnaye, Franz Schaefer, Marjolein Bonthuis, Rebecca Holman, Sergey Baiko, Esra Baskın, Anna Bjerre, Sylvie Cloarec, Elisabeth A M Cornelissen, Laura Espinosa, James Heaf, Rosário Stone, Diamant Shtiza, Ilona Zagozdzon, Jérôme Harambat, Kitty J Jager, Jaap W Groothoff, Karlijn J van Stralen
BACKGROUND: We explored the variation in country mortality rates in the paediatric population receiving renal replacement therapy across Europe, and estimated how much of this variation could be explained by patient-level and country-level factors. METHODS: In this registry analysis, we extracted patient data from the European Society for Paediatric Nephrology/European Renal Association-European Dialysis and Transplant Association (ESPN/ERA-EDTA) Registry for 32 European countries...
March 20, 2017: Lancet
https://www.readbyqxmd.com/read/28335665/calcium-oxalate-crystals-induces-tight-junction-disruption-in-distal-renal-tubular-epithelial-cells-by-activating-ros-akt-p38-mapk-signaling-pathway
#8
Lei Yu, Xiuguo Gan, Xukun Liu, Ruihua An
Tight junction plays important roles in regulating paracellular transports and maintaining cell polarity. Calcium oxalate monohydrate (COM) crystals, the major crystalline composition of kidney stones, have been demonstrated to be able to cause tight junction disruption to accelerate renal cell injury. However, the cellular signaling involved in COM crystal-induced tight junction disruption remains largely to be investigated. In the present study, we proved that COM crystals induced tight junction disruption by activating ROS/Akt/p38 MAPK pathway...
November 2017: Renal Failure
https://www.readbyqxmd.com/read/28328233/long-term-neurodevelopmental-outcome-of-neonates-with-hypernatremic-dehydration
#9
Hassan Boskabadi, Javad Akhondian, Maliheh Afarideh, Gholamali Maamouri, Sepideh Bagheri, Seyyed Mostafa Parizadeh, Majid Ghayour Mobarhan, Shabnam Mohammadi, Gordon A A Frens
BACKGROUND: Neonatal hypernatremic dehydration (NHD) is a dangerous condition that can lead to severe weight loss, renal impairment, and central nervous system complications. We aimed to evaluate the consequences of NHD in infants in their second year of life. MATERIALS AND METHODS: This was a prospective case-control study in Ghaem hospital, Mashhad, Iran. Sixty-five healthy breastfed neonates (serum sodium concentration <150 mmol/L) and 65 hypernatremic (serum sodium concentration ≥150 mmol/L) neonates were followed up from 2008 to 2011...
March 22, 2017: Breastfeeding Medicine: the Official Journal of the Academy of Breastfeeding Medicine
https://www.readbyqxmd.com/read/28326800/safety-feasibility-and-efficacy-of-bilateral-synchronous-percutaneous-nephrolithotomy-for-bilateral-stone-disease-evidence-from-a-systematic-review
#10
Patrick Jones, Blessing Dhliwayo, Bhavan Prasad Rai, Moeketsi Mokete, Ramachandran Amitharaj, Omar M Aboumarzouk, Bhaskar K Somani
INTRODUCTION: With the evolution of endourologic technology, bilateral synchronous percutaneous nephrolithotomy (BS-PCNL) has emerged as a potentially practical intervention for patients with bilateral lithiasis. Although tradition has favored a staged approach, an increasing number of original studies have reported their experiences with the synchronous approach. MATERIALS AND METHODS: A Cochrane style search was performed after development of a sensitive and predefined search strategy...
March 22, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/28324108/hypoparathyroidism-less-severe-hypocalcemia-with-treatment-with-vitamin-d2-compared-to-calcitriol
#11
Elizabeth A Streeten, Yasaman Mohtasebi, Manige Konig, Lisa Davidoff, Kathleen Ryan
Context: Options for chronic treatment of hypoparathyroidism include calcitriol, recombinant human parathyroid hormone and high dose vitamin D (D2). D2 is used in a minority because of fear of prolonged hypercalcemia and renal toxicity. There is a paucity of recent data about D2 use in hypoparathyroidism. Objective: Compare renal function, hypercalcemia and hypocalcemia in patients with hypoparathyroidism treated chronically with either D2 or calcitriol. Design, setting, patients: A retrospective study of patients with hypoparathyroidism treated at University of Maryland Hospital...
January 23, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28322903/urological-management-and-complications-in-spinal-cord-injury-patients-a-40-to-50-year-follow-up-study
#12
Yunliang Gao, Teresa Danforth, David Ginsberg
OBJECTIVES: To assess the management and types of urological complications in spinal cord injury (SCI) patients and to explore the risk factors for these complications. METHODS: 43 SCI patients with a median follow-up of 45 (range 40 to 50) years were included in this retrospective study. All medical charts were reviewed for demographics, urological complications and bladder management. RESULTS: Recurrent urinary tract infection (UTI) was noted in all patients, with an average incidence of 6...
March 16, 2017: Urology
https://www.readbyqxmd.com/read/28321250/percutaneous-nephrolithotomy-under-ultrasound-guidance-in-patients-with-renal-calculi-and-autosomal-dominant-polycystic-kidney-disease-a-report-of-11-cases
#13
Xiao Wang, Xuecheng Yang, Xiulong Zhong, Zhenlin Wang, Senyao Xue, Weifeng Yu, Zhen Dong
Nephrolithiasis accelerates the renal failure in the patients with ADPKD. In order to evaluate the role of percutaneous nephrolithotomy in management of calculus in these patients, 11 patients with autosomal dominant polycystic kidney disease and renal stones were included in the study. Two patients had bilateral renal stones. All patients were treated by percutaneous nephrolithotomy under ultrasound guidance. 13 percutaneous nephrolithotomy procedures were performed in 1 stage by the urology team under ultrasound guidance...
2017: Advances in Urology
https://www.readbyqxmd.com/read/28318298/factors-associated-with-compliance-to-increased-fluid-intake-and-urine-volume-following-dietary-counseling-in-first-time-kidney-stone-patients
#14
Aziz Khambati, Richard S Matulewicz, Kent T Perry, Robert B Nadler
OBJECTIVE: Increasing fluid intake to achieve a urine volume (UV) of >2.5 L/day decreases stone events. We assessed compliance rates and demographic and clinical variables associated with increased fluid intake and UV in patients with urolithiasis following dietary counseling. MATERIALS AND METHODS: In a retrospective study, patients with a low baseline UV (<2.5 L/day) on an initial 24-hour urine collection during metabolic stone evaluation were identified between 2010 and 2015...
March 20, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/28303631/surgical-outcomes-of-percutaneous-nephrolithotomy-pcnl-in-3-402-patients-and-results-of-stone-analysis-in-1-559-patients-from-a-single-centre-in-pakistan
#15
S A H Rizvi, M Hussain, S H Askari, M Lal, M N Zafar
OBJECTIVE: To report our experience of a series of PCNL from a single centre over the last 18 years in terms of patients and stone characteristics, indications, stone clearance and complications and chemical analysis of stones in a subgroup. PATIENTS AND METHODS: We retrospectively analysed the outcomes of PCNL in 3,402 adult patients who underwent the procedure between 1997 and 2014 from a prospectively maintained database. Data analysis included patients' age, sex, laboratory investigations, imaging, punctured calyx, duration of operation, volume of irrigation fluid, radiation exposure time, blood transfusion, complications and stone free status at one-month follow-up...
March 16, 2017: BJU International
https://www.readbyqxmd.com/read/28303335/treatment-selection-for-urolithiasis-percutaneous-nephrolithomy-ureteroscopy-shock-wave-lithotripsy-and-active-monitoring
#16
Mahesh Desai, Yinghao Sun, Noor Buchholz, Andrew Fuller, Tadashi Matsuda, Brian Matlaga, Nicole Miller, Damien Bolton, Mohammad Alomar, Arvind Ganpule
Urolithiasis is a significant worldwide source of morbidity, constituting a common urological disease that affects between 10 and 15% of the world population. Recent technological and surgical advances have replaced the need for open surgery with less invasive procedures. The factors which determine the indications for percutaneous nephrolithotomy include stone factors (stone size, stone composition, and stone location), patient factors (habitus and renal anomalies), and failure of other treatment modalities (ESWL and flexible ureteroscopy)...
March 16, 2017: World Journal of Urology
https://www.readbyqxmd.com/read/28302239/hyperoxaluria-after-renal-transplantation
#17
Waqar Ahmed, Abad Ur Rehman, Sumit Acharya
Primary hyperoxaluria is a rare autosomal recessive disorder, characterised by precipitation of insoluble oxalate crystals in the joints, kidneys, heart, eyes, skin, nerves, and bone marrow. The patients of primary oxaluria usually present with renal stone/nephrocalcinosis, and isolated kidney transplantation should not be done in these patients. We present a case report of 31-year lady with acute graft dysfunction due to oxaluria with no history of nephrolithiasis/nephrocalcinosis prior to renal transplantation...
March 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28299761/comparison-of-percutaneous-nephrolithotomy-and-retrograde-intrarenal-surgery-in-treating-20-40-mm-renal-stones
#18
Gokhan Atis, Meftun Culpan, Eyup Sabri Pelit, Cengiz Canakci, Ismail Ulus, Bilal Gunaydin, Asif Yildirim, Turhan Caskurlu
PURPOSE: To compare the outcomes of percutaneous nephrolithotomy (PCNL) and retrograde intrarenal surgery (RIRS) in treating renal stones between 20 and 40 mm in diameter. MATERIALS AND METHODS: 146 patients, who were treated with RIRS and 146 patients, who were treated with PCNL for renal stones between 20 and 40 mm in diameter were compared retrospectively using a matched-pair analysis. The operative and post-operative outcomes of both groups were analyzed retrospectively...
March 16, 2017: Urology Journal
https://www.readbyqxmd.com/read/28299446/do-renal-stones-that-fail-lithotripsy-require-treatment
#19
Ben Pullar, Catherine Lunter, Jane Collie, Syed Shah, Nimish Shah, Sami Hayek, Oliver J Wiseman
The rates of extracorporeal shock wave lithotripsy (SWL) appear stable in the UK. However, there is little evidence on the natural history of these calculi if SWL fails. We set to look at the effectiveness of SWL in patients with a single, previously untreated renal stone and the natural history of those stones that failed treatment. We retrospectively reviewed all data from our prospectively collected database of patients undergoing a first treatment for a single renal stone between October 2010 and November 2013...
March 15, 2017: Urolithiasis
https://www.readbyqxmd.com/read/28292209/risks-and-benefits-of-postoperative-double-j-stent-placement-after-ureteroscopy-urs-results-from-the-clinical-research-office-of-endourological-society-urs-global-study
#20
Ahmet Yaser Muslumanoglu, Sven Fuglsig, Antonio Frattini, Gaston Labate, Robert B Nadler, Alexey Martov, Carson Wong, Jean J M C H de la Rosette
PURPOSE: Double-J stent placement following stone removal by URS is common and recommended in many cases but debatable in others. In this study the risks and benefits of postoperative double-J stent placement in URS stone treatment procedures undertaken in current clinical practice, are examined. MATERIALS AND METHODS: The CROES URS is a prospective, observational, international, multicentre study in which patients who were candidates for URS as primary treatment or after failure of prior treatment for ureteral stones and renal stones...
March 14, 2017: Journal of Endourology
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