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https://www.readbyqxmd.com/read/28905777/re-primary-swl-is-an-efficient-and-cost-effective-treatment-for-lower-pole-renal-stones-between-10-and-20%C3%A2-mm-in-size-a-large-single-center-study
#1
https://www.readbyqxmd.com/read/28900827/lifetime-radiation-exposure-in-patients-with-recurrent-nephrolithiasis
#2
REVIEW
Mohamed A Elkoushy, Sero Andonian
Patients presenting with nephrolithiasis often undergo repeated imaging studies before, during, and after management. Considering the significant risk of stone recurrence in primary stone-formers, repeated imaging studies are not uncommon. Cumulative effects of ionizing radiation exposure from various imaging studies could potentially increase the risk for developing cataracts and solid malignancies in urolithiasis patients. Therefore, practitioners planning or performing imaging studies with ionizing radiation are compelled to keep radiation exposure to humans and the environment as low as possible, thus strictly adhering to the ALARA (As Low as Reasonably Achievable) principles...
September 12, 2017: Current Urology Reports
https://www.readbyqxmd.com/read/28895477/prospective-comparative-study-of-the-efficacy-and-safety-of-new-generation-versus-first-generation-system-for-super-mini-percutaneous-nephrolithotomy-smp-a-revolutionary-approach-to-improve-endoscopic-vision-and-stone-removal
#3
Guohua Zeng, Wei Zhu, Yang Liu, Junhong Fan, Wayne Lam, Yu Lan, Chao Cai, Tuo Deng, Xiaohang Li, Zhijian Zhao
Purpose The study sought to compare the procedural and clinical results of SMP with the use of the first- and new- generation devices. Methods A prospective, comparative cohort study was carried out between February 2013 to January 2017. Patients who underwent either first or new-generation SMP were eligible for the study. Inclusion criteria were adult patients with renal stone <4 cm, or in pediatric patients with renal stone < 2.5cm with a history of failed SWL. The primary outcome of the present study was the operating time, which was calculated from the starting of percutaneous puncture to the wound closure...
September 12, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/28894842/retroperitoneal-actinomycosis-a-rare-sequela-of-an-infected-obstructing-ureteral-stone
#4
Elizabeth Bearrick, Colby A Dixon, Joshua Rhein, Michael S Borofsky
Background: Actinomycosis is a condition in which Actinomyces, a normal component of the oral and gastrointenstial flora, becomes pathogenic in the setting of damaged tissue, leading to widespread tissue destruction across fascial planes. Prior literature describing this condition is rare, particularly cases involving the retroperitoneum. In this study, we report a case of retroperitoneal actinomycosis caused by an infected, obstructing ureteral stone. Case Presentation: A 48-year-old woman with a history of substance abuse, malnutrition, and gastric bypass presented to the emergency room with a 3-week history of abdominal pain and fevers...
2017: Journal of Endourology Case Reports
https://www.readbyqxmd.com/read/28893421/whole-exome-sequencing-frequently-detects-a-monogenic-cause-in-early-onset-nephrolithiasis-and%C3%A2-nephrocalcinosis
#5
Ankana Daga, Amar J Majmundar, Daniela A Braun, Heon Yung Gee, Jennifer A Lawson, Shirlee Shril, Tilman Jobst-Schwan, Asaf Vivante, David Schapiro, Weizhen Tan, Jillian K Warejko, Eugen Widmeier, Caleb P Nelson, Hanan M Fathy, Zoran Gucev, Neveen A Soliman, Seema Hashmi, Jan Halbritter, Margarita Halty, Jameela A Kari, Sherif El-Desoky, Michael A Ferguson, Michael J G Somers, Avram Z Traum, Deborah R Stein, Ghaleb H Daouk, Nancy M Rodig, Avi Katz, Christian Hanna, Andrew L Schwaderer, John A Sayer, Ari J Wassner, Shrikant Mane, Richard P Lifton, Danko Milosevic, Velibor Tasic, Michelle A Baum, Friedhelm Hildebrandt
The incidence of nephrolithiasis continues to rise. Previously, we showed that a monogenic cause could be detected in 11.4% of individuals with adult-onset nephrolithiasis or nephrocalcinosis and in 16.7-20.8% of individuals with onset before 18 years of age, using gene panel sequencing of 30 genes known to cause nephrolithiasis/nephrocalcinosis. To overcome the limitations of panel sequencing, we utilized whole exome sequencing in 51 families, who presented before age 25 years with at least one renal stone or with a renal ultrasound finding of nephrocalcinosis to identify the underlying molecular genetic cause of disease...
September 8, 2017: Kidney International
https://www.readbyqxmd.com/read/28891311/does-previous-open-renal-stone-surgery-affect-the-outcome-of-swl-treatment-in-adults-with-renal-stones
#6
Mehmet Hamza Gultekin, Fethi Ahmet Turegun, Burak Ozkan, Beril Tulu, Gamze Gul Gulec, Nejat Tansu, Cetin Demirdag, Pınar Kendigelen, Ahmet Erozenci, Bulent Onal
PURPOSE: To evaluate the effects of previous ipsilateral open renal stone surgery (ORSS) on outcomes of extracorporeal shockwave lithotripsy (SWL) in adults with renal stones. MATERIAL AND METHODS: A total of 2097 renal units (RUs) with renal stones underwent SWL treatment at our institution between March 1997 and February 2013. 1839 (87.7%) of these had no history of ORSS and were categorized as group 1 and 258 (12.3 %) patients having previous history of ipsilateral ORSS were categorized as group 2...
September 11, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/28885161/virtual-and-augmented-reality-systems-for-renal-interventions-a-systematic-review
#7
Felicitas J Detmer, Julian Hettig, Daniel Schindele, Martin Schostak, Christian Hansen
Many virtual and augmented reality systems have been proposed to support renal interventions. This paper reviews such systems employed in the treatment of renal cell carcinoma and renal stones.
September 6, 2017: IEEE Reviews in Biomedical Engineering
https://www.readbyqxmd.com/read/28882781/ureteroscopic-urinary-stone-treatment-among-patients-with-renal-anomalies-patient-characteristics-and-treatment-outcomes
#8
Jaap D Legemate, Barbaros Baseskioglu, Jakub Dobruch, Jorge Gutierrez-Aceves, Oscar Negrete, Carlos Rioja Sanz, Muharrem Murat Yildiz, Jean Jmch de la Rosette
OBJECTIVES: To evaluate patients' characteristics, surgical procedure data, and outcomes of URS stone treatment in patients with a horseshoe kidney (HSK), ectopic kidney (EK), and malrotated kidney (MK). METHODS: This study is a sub-analysis of the CROES URS Global Study, which was a prospective multicenter observational study, collecting data on URS stone treatment from consecutive patients over a 1-year period. 114 Centers participated in 32 countries. This analysis acuminated on URS stone treatment in the specified renal anomalies: HSK, EK and MK...
September 4, 2017: Urology
https://www.readbyqxmd.com/read/28882031/a-multiregional-italian-cohort-of-24-hour-urine-metabolic-evaluation-in-renal-stone-formers
#9
Francesco Esperto, Martino Marangella, Alberto Trinchieri, Michele Petrarulo, Roberto Miano
BACKGROUND: Nephrolithiasis is a common condition with several studies documenting an increased prevalence over the past four decades. EAU and AUA guidelines recommend 24-hour urine metabolic evaluation in high-risk stone formers. Aim of this study is to retrospectively evaluate the first three years of experience with Lithotest® (Biohealth Italia Srl, Turin, Italy) through the analysis of demographic, clinical and biochemical data collected from a large cohort of patients with kidney stones...
September 7, 2017: Minerva Urologica e Nefrologica, the Italian Journal of Urology and Nephrology
https://www.readbyqxmd.com/read/28881339/interstitial-immunostaining-and-renal-outcomes-in-antineutrophil-cytoplasmic-antibody-associated-glomerulonephritis
#10
Duvuru Geetha, Sanjeev Sethi, An S De Vriese, Ulrich Specks, Cees G M Kallenberg, Noha Lim, Robert Spiera, E William St Clair, Peter A Merkel, Philip Seo, Paul A Monach, Nicola Lepori, Barri J Fessler, Carol A Langford, Gary S Hoffman, Rishi Sharma, John H Stone, Fernando C Fervenza
BACKGROUND: Immunopathologic features predict renal function at baseline and follow-up in antineutrophil cytoplasmic antibody (ANCA)-associated glomerulonephritis (GN). The interstitial infiltrate consists predominantly of T lymphocytes, but their pathophysiologic significance is unclear, especially in light of the success of B-cell-directed therapy. METHODS: Renal biopsies from 33 patients treated with cyclophosphamide (CYC; n = 17) or rituximab (RTX; n = 16) in the RTX in ANCA-associated vasculitis (RAVE) trial were classified according to the new ANCA GN classification...
September 8, 2017: American Journal of Nephrology
https://www.readbyqxmd.com/read/28875258/molecular-analysis-of-oxalate-induced-endoplasmic-reticulum-stress-mediated-apoptosis-in-the-pathogenesis-of-kidney-stone-disease
#11
Albert Abhishek, Shaly Benita, Monika Kumari, Divya Ganesan, Eldho Paul, Ponnusamy Sasikumar, Ayyavu Mahesh, Subramani Yuvaraj, Tharmarajan Ramprasath, Govindan Sadasivam Selvam
Oxalate, a non-essential end product of metabolism, causes hyperoxaluria and eventually calcium oxalate (CaOx) stone disease. Kidney cells exposed to oxalate stress results in generation of reactive oxygen species (ROS) and progression of stone formation. Perturbations in endoplasmic reticulum (ER) result in accumulation of misfolded proteins and Ca(2+) ions homeostasis imbalance and serve as a common pathway for various diseases, including kidney disorders. ER stress induces up-regulation of pro-survival protein glucose-regulated protein 78 (GRP78) and pro-apoptotic signaling protein C/EBP homologous protein (CHOP)...
September 5, 2017: Journal of Physiology and Biochemistry
https://www.readbyqxmd.com/read/28873326/external-validation-and-comparisons-of-the-scoring-systems-for-predicting-percutaneous-nephrolithotomy-outcomes-a-single-center-experience-with-506-cases
#12
Serkan Yarimoglu, Ibrahim Halil Bozkurt, Ozgu Aydogdu, Tarik Yonguc, Bulent Gunlusoy, Tansu Degirmenci
BACKGROUND: To validate and compare the stone scoring systems (stone size [S], tract length [T], obstruction [O], number of involved calices [N], and essence or stone density [E] [S.T.O.N.E.], Guy's Stone Score [GSS], Clinical Research Office of the Endourological Society [CROES], and Seoul National University Renal Stone Complexity [S-ReSC]) used to predict postoperative stone-free status and complications after percutaneous nephrolithotomy (PCNL). METHODS: A total of 567 patients who underwent PCNL for renal stones between January 2012 and August 2015 were included in the recent retrospective study...
September 5, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/28868505/radiological-noninvasive-assessment-of-ureteral-stone-impaction-into-the-ureteric-wall-a-critical-evaluation-with-objective-radiological-parameters
#13
Ozlem Elibol, Kadihan Yalcin Safak, Ayse Buz, Bilal Eryildirim, Kutluhan Erdem, Kemal Sarica
PURPOSE: To determine the predictive value of certain radiological parameters for an objective asssessment of the presence of ureteral stone impaction. MATERIALS AND METHODS: Seventy-nine patients with a single proximal ureteral stones were retrieved from the departmental database. Both clinical and particularly radiological data of all cases were well evaluated on this aspect. In addition to the time period between the first colic attack and definitive management; diameter of proximal ureter and renal pelvis, longitudinal and transverse stone size, Hounsfied unit (HU) of the stone and lastly ureteral wall thickness at the impacted stone site were all carefully evaluated and noted...
September 2017: Investigative and Clinical Urology
https://www.readbyqxmd.com/read/28865885/stone-growth-patterns-and-risk-for-surgery-among-children-presenting-with-hypercalciuria-hypocitraturia-and-cystinuria-as-underlying-metabolic-causes-of-urolithiasis
#14
F Zu'bi, M Sidler, E Harvey, R I Lopes, A Hojjat, N Naoum, M Pokarowski, A J Lorenzo, W A Farhat, F Papanikolaou, J Dos Santos
INTRODUCTION: Hypercalciuria, hypocitraturia and cystinuria are the most common underlying metabolic stone abnormalities in children. The present study compared stone growth patterns, stone burden, and the risk of stone-related surgery among these underlying metabolic conditions. METHODS: A retrospective cohort of 356 children with renal stones, followed from 2000 to 2015, was studied. Differences among metabolic groups were determined using Kruskal-Wallis test; the Scheffé-test was used for multiple comparisons to determine differences among single groups...
August 4, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28861303/flouroscopy-free-technique-is-safe-and-feasible-in-retrograde-intrarenal-surgery-for-renal-stones
#15
Hacı İbrahim Çimen, Fikret Halis, Hasan Salih Sağlam, Ahmet Gökçe
OBJECTIVE: The aim of this study was to present outcomes of our patients who had undergone retrograde intrarenal surgery (RIRS) with fluoroscopy-free technique and evaluate the efficacy and safety of the technique. MATERIAL AND METHODS: Between January 2013 and June 2015 the outcomes of 93 patients who had undergone RIRS with fluoroscopy-free technique were retrospectively evaluated. Our RIRS technique involved preoperative assessment of ureter by semi-rigid ureteroscope, inserting guidewire through semi-rigid ureteroscope, inserting ureteral access sheath over the guidewire with the visiual guidance of semi-rigid ureteroscope, passing flexible ureteroscope through the sheath, dusting the stone with holmium laser, rechecking the ureter with semi-rigid ureteroscope and inserting double J stent through semi-rigid ureteroscope...
September 2017: Turkish Journal of Urology
https://www.readbyqxmd.com/read/28861302/factors-associated-with-postoperative-pain-after-retrograde-intrarenal-surgery-for-kidney-stones
#16
Ural Oğuz, Tolga Şahin, Çağrı Şenocak, Ekrem Özyuvalı, Ömer Faruk Bozkurt, Berkan Reşorlu, Ali Ünsal
OBJECTIVE: We aimed to investigate factors related to early postoperative pain after retrograde intrarenal surgery (RIRS). MATERIAL AND METHODS: A prospective data analysis of 250 patients who underwent RIRS due to kidney stones was performed. Postoperative pain was evaluated in all patients by using visual analogue scale (VAS). Patients with severe pain (VAS score ≥7) were separated and included in Group I (n=46). While patients without pain or with insignificant pain were included in Group II (n=204)...
September 2017: Turkish Journal of Urology
https://www.readbyqxmd.com/read/28861294/retrograde-intrarenal-surgery-for-renal-stones-part-2
#17
REVIEW
Özcan Kılıç, Murat Akand, Ben Van Cleynenbreugel
Retrograde intrarenal surgery (RIRS) has become an effective and safe treatment modality in the management of urinary system stone disease. Recent developments and innovations in the flexible ureterorenoscope and auxiliary equipment have made this procedure easier and more effective with increased success rates. RIRS can be used as a primary treatment in patients with renal stones smaller than 2 cm, prior unsuccessful shock wave lithotripsy, infundibular stenosis, renoureteral malformation, skeletal-muscular deformity, bleeding diathesis and obese patients...
September 2017: Turkish Journal of Urology
https://www.readbyqxmd.com/read/28859655/management-of-large-renal-stones-laparoscopic-pyelolithotomy-versus-percutaneous-nephrolithotomy
#18
Yunjin Bai, Yin Tang, Lan Deng, Xiaoming Wang, Yubo Yang, Jia Wang, Ping Han
BACKGROUND: Percutaneous nephrolithotomy (PCNL) remains the standard procedure for large (≥2 cm) renal calculi; however, laparoscopic pyelolithotomy (LPL) can be used as an alternative management procedure. The aim of present study was to compare LPL and PCNL in terms of efficacy and safety for the management of large renal pelvic stones. METHODS: A literature search was performed in Jan 2016 using electronic databases (Cochrane Central Register of Controlled Trials, Medline, and EMBASE) to identify relevant studies for the meta-analysis...
August 31, 2017: BMC Urology
https://www.readbyqxmd.com/read/28859496/the-effect-of-physician-specialty-obtaining-access-for-percutaneous-nephrolithotomy-on-perioperative-costs-and-outcomes
#19
Jacqueline M Speed, Ye Wang, Jeffrey J Leow, Naeem Bhojani, Quoc-Dien Trinh, Steven Chang, Ruslan Korets
OBJECTIVE: To evaluate the impact of the specialty (urologist versus radiologist) of the physician obtaining percutaneous renal access (RA) on perioperative outcomes, complications, and costs of percutaneous nephrolithotomy (PCNL). METHODS: We used data from a national hospital discharge database to identify patients undergoing PCNL between 2003-2015. Procedure codes related to RA were linked to physician specialty. We examined patient demographics, Charlson comorbidity index (CCI), postoperative complications, length of stay (LOS), and direct hospital costs as well as hospital and surgeon characteristics stratified by specialty of the physician obtaining RA...
August 31, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/28858562/evaluation-of-kidney-stones-with-reduced-radiation-dose-ct-progress-from-2011-2012-to-2015-2016-not-there-yet
#20
Karrin Weisenthal, Priyadarshini Karthik, Melissa Shaw, Debapriya Sengupta, Mythreyi Bhargavan-Chatfield, Judy Burleson, Adel Mustafa, Mannudeep Kalra, Christopher Moore
Purpose To determine if the use of reduced-dose computed tomography (CT) for evaluation of kidney stones increased in 2015-2016 compared with that in 2011-2012, to determine variability in radiation exposure according to facility for this indication, and to establish a current average radiation dose for CT evaluation for kidney stones by querying a national dose registry. Materials and Methods This cross-sectional study was exempt from institutional review board approval. Data were obtained from the American College of Radiology dose registry for CT examinations submitted from July 2015 to June 2016...
August 31, 2017: Radiology
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