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https://www.readbyqxmd.com/read/29146111/microrna-expression-patterns-in-human-anterior-cingulate-and-motor-cortex-a-study-of-dementia-with-lewy-bodies-cases-and-controls
#1
Peter T Nelson, Wang-Xia Wang, Sarah A Janse, Katherine L Thompson
OVERVIEW: MicroRNAs (miRNAs) have been implicated in neurodegenerative diseases including Parkinson's disease and Alzheimer's disease (AD). Here, we evaluated the expression of miRNAs in anterior cingulate (AC; Brodmann area [BA] 24) and primary motor (MO; BA 4) cortical tissue from aged human brains in the University of Kentucky AD Center autopsy cohort, with a focus on dementia with Lewy bodies (DLB). METHODS: RNA was isolated from gray matter of brain samples with pathology-defined DLB, AD, AD+DLB, and low-pathology controls, with n=52 cases initially included (n=23 with DLB), all with low (<4hrs) postmortem intervals...
November 13, 2017: Brain Research
https://www.readbyqxmd.com/read/29146028/functional-and-anatomic-correlates-of-neural-aging-in-birds
#2
REVIEW
Mary Ann Ottinger
Avian species show variation in longevity, habitat, physiologic characteristics, and lifetime endocrine patterns. Lifetime reproductive and metabolic function vary. Much is known about the neurobiology of the song system in many altricial birds. Little is known about aging in neural systems in birds. Captive birds often survive beyond the age they would in the wild, providing an opportunity to gain an understanding of the physiologic and neural changes. This paper reviews the available information with the goal of capturing areas of potential investigation into gaps in our understanding of neural aging as reflected in physiologic, endocrine, and cognitive aging...
January 2018: Veterinary Clinics of North America. Exotic Animal Practice
https://www.readbyqxmd.com/read/29142436/high-performance-thin-layer-chromatographic-densitometric-quantification-and-recovery-of-bioactive-compounds-for-identification-of-elite-chemotypes-of-gloriosa-superba-l-collected-from-sikkim-himalayas-india
#3
Ankita Misra, Pushpendra Kumar Shukla, Bhanu Kumar, Jai Chand, Poonam Kushwaha, Md Khalid, Ajay Kumar Singh Rawat, Sharad Srivastava
Background: Gloriosa superba L. (Colchicaceae) is used as adjuvant therapy in gout for its potential antimitotic activity due to high colchicine(s) alkaloids. Objective: This study aimed to develop an easy, cheap, precise, and accurate high-performance thin-layer chromatographic (HPTLC) validated method for simultaneous quantification of bioactive alkaloids (colchicine and gloriosine) in G. superba L. and to identify its elite chemotype(s) from Sikkim Himalayas (India)...
October 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/29141045/csf-in-the-ventricles-of-the-brain-behaves-as-a-relay-medium-for-arteriovenous-pulse-wave-phase-coupling
#4
William E Butler, Pankaj K Agarwalla, Patrick Codd
The ventricles of the brain remain perhaps the largest anatomic structure in the human body without established primary purpose, even though their existence has been known at least since described by Aristotle. We hypothesize that the ventricles help match a stroke volume of arterial blood that arrives into the rigid cranium with an equivalent volume of ejected venous blood by spatially configuring cerebrospinal fluid (CSF) to act as a low viscosity relay medium for arteriovenous pulse wave (PW) phase coupling...
2017: PloS One
https://www.readbyqxmd.com/read/29139133/cranial-shape-variation-in-jacarean-caimanines-crocodylia-alligatoroidea-and-its-implications-in-the-taxonomic-status-of-extinct-species-the-case-of-melanosuchus-fisheri
#5
Christian Foth, María Victoria Fernandez Blanco, Paula Bona, Torsten M Scheyer
Melanosuchus niger (Crocodylia, Alligatoroidea) is one of the six living caimanine species widely distributed throughout the Amazon River basin today. Although there is only one extant species of Melanosuchus, fossil material assigned to this genus, represented by M. fisheri, has been reported from the late Miocene in South America. However, the validity of this taxon has been questioned and a recent investigation indicates that the referred specimen of M. fisheri (MCZ 4336) actually belongs to Globidentosuchus brachyrostris, while those diagnostic characters present in the holotype (MCNC 243) fall into the spectrum of intraspecific variation of M...
November 15, 2017: Journal of Morphology
https://www.readbyqxmd.com/read/29138875/variant-course-of-extensor-pollicis-brevis-tendon-in-the-third-extensor-compartment
#6
Shiro Sugiura, Yusuke Matsuura, Takane Suzuki, Satoru Nishikawa, Chisato Mori, Kazuki Kuniyoshi
INTRODUCTION: According to the anatomical literature, the extensor pollicis brevis (EPB) tendon passes through the first compartment and enters the base of the proximal phalanx of the thumb. There have been a few reports on the different types of supernumerary EPB tendons; however, an unusual course of the EPB tendon is extremely rare. MATERIALS AND METHODS: During routine cadaveric dissection in the Department of Gross Anatomy, we detected an variant EPB muscle in a 96-year-old fresh female cadaver...
November 14, 2017: Surgical and Radiologic Anatomy: SRA
https://www.readbyqxmd.com/read/29137915/first-line-direct-access-for-transarterial-embolization-of-a-dural-arteriovenous-fistula-case-report-and-literature-review
#7
Brent J Doolan, Iddo Paldor, Peter J Mitchell, Andrew P Morokoff
Intracranial dural arteriovenous fistulae (DAVF) are complex vascular malformations consisting of a pathological shunt located between meningeal arteries and drainage to dural venous sinuses and/or cerebral veins. We report an unusual anatomical variation, resulting in a DAVF forming between the superior sagittal sinus and an anomalous origin of the middle meningeal artery (MMA) arising from the left ophthalmic artery. We present an atypical case requiring mini-craniotomy for catheter access, as well as cannulation of extracranial arterial supply prior to embolization of a Cognard type IIa+b fistula...
November 11, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/29136730/-application-of-the-descending-branch-of-the-lateral-circumflex-femoral-artery-in-the-coronary-artery-bypass-grafting-operation
#8
X J Luo, W Wang, Y T Wang, Y Yang, H Li, X Wang, S S Hu
Objective: To investigate the technical method for harvesting and application of the descending branch of the lateral circumflex femoral artery (DBLCFA) in the coronary artery bypass grafting (CABG) operation. Methods: Between December 2016 and April 2017, 19 patients were arranged to use DBLCFA and got CT angiography (CTA) of pelvic and femoral arteries pre-operative at Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College. Finally, DBLCFA was harvested in 16 patients (including 2 female patients, with a mean age of (47...
November 1, 2017: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/29134424/anatomical-basis-for-simultaneous-block-of-greater-and-third-occipital-nerves-with-an-ultrasound-guided-technique
#9
Ken Kariya, Yosuke Usui, Naoko Higashi, Tatsuo Nakamoto, Hironobu Shimbori, Satoshi Terada, Hideo Takahashi, Hisashi Ueta, Yusuke Kitazawa, Yasushi Sawanobori, Yasuhisa Okuda, Kenjiro Matsuno
PURPOSE: In some headache disorders, for which the greater occipital nerve block is partly effective, the third occipital nerve is also suggested to be involved. We aimed to establish a simple technique for simultaneously blocking the greater and third occipital nerves. METHODS: We performed a detailed examination of dorsal neck anatomy in 33 formalin-fixed cadavers, and deduced two candidate target points for blocking both the greater and third occipital nerves...
November 13, 2017: Journal of Anesthesia
https://www.readbyqxmd.com/read/29133232/embryological-and-comparative-description-of-the-cephalic-vein-joining-the-external-jugular-vein-a-case-report
#10
R C Araújo, L A S Pires, M L Andrade, M C Perez, C S L Filho, M A Babinski
The cephalic vein arises from the radial end of the dorsal venous arch. It turns around the radial border of the forearm and passes proximally along the arm to the shoulder, where it enters the axillary vein by penetrating the clavipectoral triangle. The cephalic vein is prone to vary at the antecubital fossa, where it forms numerous anastomoses. A male cadaver fixated with a 10% formalin solution was dissected during regular anatomy lessons. It was found that the cephalic vein crossed the upper third of the arm between two fasciculi of the deltoid muscle and reached the shoulder, where it passed above the acromion and crossed the posterior border of the clavicle in order to join the external jugular vein...
November 10, 2017: Morphologie: Bulletin de L'Association des Anatomistes
https://www.readbyqxmd.com/read/29132101/contributions-of-the-layer-topology-and-mineral-content-to-the-elastic-modulus-and-strength-of-fish-scales
#11
Sandra Murcia, Yuri Miyamoto, Megha Pratap Varma, Alexander Ossa, Dwayne Arola
Fish scales are an interesting natural structural material and their functionality requires both flexibility and toughness. Our previous studies identified that there are spatial variations in the elastic properties of fish scales corresponding to the anatomical regions, and that they appear to be attributed to changes in the microstructure. In the present study, a model is proposed that describes the elastic behavior of elasmoid fish scales in terms of the relative contributions of the limiting layer and both the internal and external elasmodine...
November 7, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29131812/an-improved-distance-to-dose-correlation-for-predicting-bladder-and-rectum-dose-volumes-in-knowledge-based-vmat-planning-for-prostate-cancer
#12
Phillip D H Wall, Robert L Carver, Jonas D Fontenot
The overlap volume histogram (OVH) is an anatomical metric commonly used to quantify the geometric relationship between an organ at risk (OAR) and target volume when predicting expected dose-volumes in knowledge-based planning (KBP). This work investigated the influence of additional variables contributing to variations in the assumed linear DVH-OVH correlation for the bladder and rectum in VMAT plans of prostate patients, with the goal of increasing prediction accuracy and achievability of knowledge-based planning methods...
November 13, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29131280/the-sphenopalatine-foramen-in-man-anatomical-radiological-and-endoscopic-study
#13
Ehab Abdel Aziz El-Shaarawy, Sherif S Hassan
BACKGROUND: Epistaxis is a frequent problem otorhinolaryngologists faces of in their practice. The variations of the sphenopalatine foramen and consequently the artery may be one of the major sources of such bleeding. AIM OF THE WORK: The present work aimed at to localize the site of sphenopalatine foramen and also to illustrate its different shapes, number and any other variation. MATERIALS AND METHODS: In the current study, twenty adult skulls of both sexes with total 40 half skulls were used in addition to 20 heads of adult living subjects of both sexes aged between 30-60 years examined with multislice helical CT with 3-D reconstruction of SPF...
November 13, 2017: Folia Morphologica (Warsz)
https://www.readbyqxmd.com/read/29131235/anatomical-variations-of-brachial-plexus-in-fetal-cadavers
#14
Alparslan Kirik, Senem Ertuğrul Mut, Mehmet Kadri Daneyemez, Halil İbrahim Seçer
AIM: The plexus brachialis is a complex structure with anatomical variations and connections with neighboring tissues. These variations may cause disparity in the motor and sensorial innervations of the upper extremity. The knowledge of anatomy and probable variations are important for performing surgical procedures in the neck, shoulder and axilla. This study was planned to demonstrate the anatomical variations of infantile brachial plexus. MATERIAL AND METHODS: A total of 20 plexus brachialis from 11 fetal cadavers were dissected and examined microscopically...
October 18, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/29127734/population-representation-among-anatomical-donors-and-the-implication-for-medical-student-education
#15
Amanda J Collins, Whitney Smith, Eustathia Lela Giannaris, Elizabeth Orvek, Peter Lazar, Jan K Carney, Anne M Gilroy, Max P Rosen
INTRODUCTION: Dissection provides a unique opportunity to integrate anatomical and clinical education. Commonly, cadavers are randomly assigned to courses, which may result in skewed representation of patient populations. The primary aim of this study was to determine if the anatomical donors studied by students at Medical School (MS) accurately represent the disease burden of the local patient population. MATERIALS AND METHODS: This cross-sectional study compared Medical Center patient claims data and body donation data from the Anatomical Gift Program (AGP)...
November 11, 2017: Clinical Anatomy
https://www.readbyqxmd.com/read/29126239/morphometric-analysis-of-the-umbilicus-according-to-age
#16
Nicolas Correia, Laura Jayyosi, Sergiu Chiriac, Yohann Renard, Emilie Raimond, Marie Laurence Poli-Merol, Benoit Chaput, Caroline François
Background: Morphometric and anatomical analyses of the shape and position of the umbilicus have been conducted in adults, but umbilicoplasty in children remains challenging because growth is still occurring. Objectives: The main objective of this study was to evaluate the difference in the position and shape of the umbilicus between childhood and adulthood. The secondary objective was to improve the surgical management of umbilicoplasty in children. Methods: This prospective single-center study focused on the morphometric analysis of the umbilicus in 200 adults and children...
November 8, 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/29125037/an-audit-of-injuries-in-six-english-professional-soccer-academies
#17
Paul J Read, Jon L Oliver, Mark B A De Ste Croix, Gregory D Myer, Rhodri S Lloyd
Regulations now state that professional academies in the United Kingdom are required to substantially increase the volume of soccer training. This study assessed the current injury occurrence, providing an update to reports published prior to the introduction of the Elite Player Performance Plan (EPPP). 608 soccer players aged 11-18 years from six professional soccer clubs were prospectively monitored, recording injuries during the 2014-2015 season. An injury rate of 1.32 injuries per player/season was indicated with a mean time loss of 21...
November 10, 2017: Journal of Sports Sciences
https://www.readbyqxmd.com/read/29125025/choroid-plexus-avm-with-anomalous-origin-of-the-capsulothalamic-artery-a-case-report
#18
Shigeru Yamauchi, Taichiro Kawakami, Keiji Murata, Tomoya Ishiguro, Hidetoshi Ikeda, Akimasa Nishio
Background and importance Traditionally, it has been believed that the plexal segment of the anterior choroidal artery (AChoA) can be sacrificed safely. Here, we present a case of choroid plexus arteriovenous malformation (AVM) in which the capsulothalamic artery originated from distal plexal segment of the AChoA. Clinical presentation A 45-year-old man was diagnosed with arteriovenous malformation involving the left inferior horn in screening MRI. Preceding stereotactic radiosurgery, transarterial target embolization was performed...
January 1, 2017: Interventional Neuroradiology
https://www.readbyqxmd.com/read/29124505/transitions-between-asynchronous-and-synchronous-states-a-theory-of-correlations-in-small-neural-circuits
#19
Diego Fasoli, Anna Cattani, Stefano Panzeri
The study of correlations in neural circuits of different size, from the small size of cortical microcolumns to the large-scale organization of distributed networks studied with functional imaging, is a topic of central importance to systems neuroscience. However, a theory that explains how the parameters of mesoscopic networks composed of a few tens of neurons affect the underlying correlation structure is still missing. Here we consider a theory that can be applied to networks of arbitrary size with multiple populations of homogeneous fully-connected neurons, and we focus its analysis to a case of two populations of small size...
November 10, 2017: Journal of Computational Neuroscience
https://www.readbyqxmd.com/read/29124345/a-rare-anatomic-variation-of-the-superficial-palmar-branch-of-the-radial-artery-causing-pain
#20
Georg Singer, Robert Marterer, Holger Till, Barbara Schmidt
BACKGROUND: The superficial palmar branch of the radial artery (SPBRA) normally pierces through the thenar muscles and unites with the ulnar artery to form the superficial palmar arch. Rarely, a subcutaneous course of the SPBRA is described in which the artery lies superficial to the thenar muscles. CASE REPORT: We report about a 17-year-old female patient with pain at the thenar eminence due to a unique course of the SPBRA. Duplex sonography and magnetic resonance angiography revealed a subcutaneous course of the artery over the thenar muscles...
November 9, 2017: Surgical and Radiologic Anatomy: SRA
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