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Bennet's lesion

Carles Juan-Sallés, Liliana Sofía Martínez, Arely G Rosas-Rosas, Alberto Parás, Osvaldo Martínez, Alejandra Hernández, Michael M Garner
Subacute and chronic mountain sickness of humans and the related brisket disease of cattle are characterized by right-sided congestive heart failure in individuals living at high altitudes as a result of sustained hypoxic pulmonary hypertension. Adaptations to high altitude and disease resistance vary among species, breeds, and individuals. The authors conducted a retrospective survey of right-sided cardiac hypertrophy associated with pulmonary arterial hypertrophy or arteriosclerosis in zoo mammals housed at Africam Safari (Puebla, México), which is located at 2,100 m above sea level...
December 2015: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
Sam Mathai, Lindsea C Booth, Joanne O Davidson, Paul P Drury, Mhoyra Fraser, Ellen C Jensen, Sherly George, Andrew Naylor, Alistair J Gunn, Laura Bennet
Acute, high-dose exposure to endotoxin lipopolysaccharide (LPS) in preterm fetal sheep can trigger periventricular white matter lesions (PVL), in association with severe hypotension/hypoxemia and significant mortality. Intriguingly, however, chronic or repeated exposure to LPS can induce tachyphylaxis. We therefore tested the hypothesis that progressive, acute on chronic fetal infection would be associated with white matter injury with little fetal mortality. Chronically instrumented preterm (0.7 gestational age) fetal sheep were exposed to a continuous low-dose LPS infusion (100 ng over 24 h, followed by 250 ng/24 h for 96 h) or saline...
February 2013: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
Jennifer J Liang, Ian Bissett, Matthew Kalady, Ana Bennet, James M Church
Colorectal cancer is an invasive neoplasm of the glandular epithelium of the colon and rectum that begins in a precursor lesion and expands to replace its lesion of origin. The majority of colorectal cancers arise from an adenoma, and the 'adenoma to carcinoma' pathway has been acknowledged for decades. More recently, another precursor lesion has been recognized: the serrated polyp. Serrated polyps are characterized by a sawtooth appearance of the crypt epithelium resulting from failure of apoptosis and a build-up of aging colonocytes...
May 2013: ANZ Journal of Surgery
S Bennet, P A McCann, I McFadyen
Pathological lesions of long bones increase the morbidity of many common cancers. The orthopedic management of metastatic skeletal lesions can be challenging. The ultimate aim is to provide patients with a painless, functional limb. We present a report of two cases were a novel minimally invasive long bone nailing technique has been utilized to achieve skeletal stability and alleviation of symptoms.
2011: Hand Surgery
Delphine Vezzosi, Caroline Capuani, Florence Loubes-Lacroix, Jacques Lagarrigue, Antoine Bennet, Marie Bernadette Delisle, Philippe Caron
CONTEXT: Primary sellar melanocytic tumors are extremely rare, and they can mimic hormonally inactive pituitary macroadenoma both clinically and radiologically. OBJECTIVES: The aim of this study was to describe a new case of primary sellar melanocytic tumor, and place it in the context of published literature. DESIGN: This is a case report. PATIENT: The case of a 61-year-old woman presenting with a 2-month history of fatigue and progressive bitemporal hemianopia is described...
2009: Pituitary
Mairi Steven, Nagarajan Kumaran, Robert Carachi, Ashish Desai, George Bennet
Haemangiomas and vascular malformations of the limb in children are often difficult to manage. The role of surgery and intervention in current management is still not clear. The aim of this study was to review our experience of such patients. Patients were identified using the health board database of inpatient admissions between 1999 and 2003. Clinical notes were reviewed and data collected looking at patient demographics, site of lesion, clinical findings, investigative procedures, intervention and follow-up...
June 2007: Pediatric Surgery International
Louise Bennet, Carl-Johan Fraenkel, Ulf Garpmo, Anders Halling, Mikael Ingman, Katharina Ornstein, Louise Stjernberg, Johan Berglund
AIM: The aim in this survey was to study the clinical characteristics of infections caused by Borrelia genospecies in patients with erythema migrans where borrelial origin was confirmed by polymerase chain reaction. The aim was also to study factors influencing the clinical appearance of erythema migrans. METHODS: The study was conducted in southern Sweden from May 2001 to December 2003 on patients 18 years and older attending with erythema migrans at outpatient clinics...
September 2006: Wiener Klinische Wochenschrift
Celia S Chen, Kerry D Phillips, Scott Grist, Graeme Bennet, Jamie E Craig, James S Muecke, Graeme K Suthers
BACKGROUND AND AIM: Congenital hypertrophy of the retinal pigment epithelium (CHRPE) is a pigmented fundus lesion associated with familial adenomatous polyposis (FAP). CHRPE prevalence has been reported to be increased in subjects with familial or sporadic non-polyposis colorectal cancer (CRC), suggesting that some individuals with non-polyposis CRC have an attenuated form of FAP. Other studies have not confirmed these clinical observations and have failed to identify mutations in the gene responsible for FAP, but the reason for the discrepancy in relation to CHRPE prevalence has not been resolved...
2006: Familial Cancer
Sara Jarefors, Louise Bennet, Elin You, Pia Forsberg, Christina Ekerfelt, Johan Berglund, Jan Ernerudh
Lyme borreliosis is a tick-borne disease often manifesting as a circular skin lesion. This cutaneous form of the disease is known as erythema migrans. In a 5-year follow-up study in southern Sweden, 31 of 708 individuals initially diagnosed with erythema migrans and treated with antibiotics were found to be reinfected with Borrelia burgdorferi. Although men and women were tick-bitten to the same extent, 27 of the 31 reinfected individuals were women, all of whom were over 44 years of age. The aim of this study was to determine whether this discrepancy in gender distribution could be a result of differences in immunological response...
June 2006: Immunology
J Guan, L Bennet, P D Gluckman, A J Gunn
It is now well established that neurons and other cell types may die many hours or even days after hypoxic-ischemic injury due to activation of programmed cell death (apoptotic) pathways. The potent anti-apoptotic factor IGF-1 and its binding proteins and receptors are intensely induced within damaged brain regions following brain injury suggesting a possible a role for IGF-1 in endogenous brain recovery. Exogenous administration of IGF-1 within a few hours after brain injury has now been shown to be protective in both grey and white matter, and leads to improved long-term neurological function...
2005: Endocrine Development
Xiaosong Wang, Massimiliano Ria, Peter M Kelmenson, Per Eriksson, David C Higgins, Ann Samnegård, Christina Petros, Jarod Rollins, Anna M Bennet, Björn Wiman, Ulf de Faire, Charlotte Wennberg, Per G Olsson, Naoto Ishii, Kazuo Sugamura, Anders Hamsten, Kristina Forsman-Semb, Jacob Lagercrantz, Beverly Paigen
Ath1 is a quantitative trait locus on mouse chromosome 1 that renders C57BL/6 mice susceptible and C3H/He mice resistant to diet-induced atherosclerosis. The quantitative trait locus region encompasses 11 known genes, including Tnfsf4 (also called Ox40l or Cd134l), which encodes OX40 ligand. Here we report that mice with targeted mutations of Tnfsf4 had significantly (P <or= 0.05) smaller atherosclerotic lesions than did control mice. In addition, mice overexpressing Tnfsf4 had significantly (P <or= 0...
April 2005: Nature Genetics
K Reddy, C Mallard, J Guan, K Marks, L Bennet, M Gunning, A Gunn, P Gluckman, C Williams
A characteristic of perinatal encephalopathies are the distinct patterns of neuronal and glial cell loss. Cerebral hypoperfusion is thought to be a major cause of these lesions. Gestational age is likely to influence outcome. This study compares the cortical electrophysiologic and histopathologic responses to hypoperfusion injury between preterm and near term fetuses. Chronically instrumented 0.65 (93-99-d, n = 9) and 0.9 (119-133-d, n = 6) gestation fetal sheep underwent 30 min of cerebral hypoperfusion injury...
May 1998: Pediatric Research
D W Stoller
This article explores MR arthrography of the glenohumeral joint, including normal anatomy of the glenoid labrum, glenohumeral ligaments, and biceps labral complex. Examples of glenohumeral joint instability include the Bankart lesion, anterior labroligamentous periosteal sleeve avulsion, glenolabral articular disruption, humeral avulsion of the glenohumeral ligament, and Bennet lesion. Normal variations include the sublabral foramen, the Buford complex, and cord-like middle glenohumeral ligament. Labral tears and paralabral cysts are also discussed...
January 1997: Radiologic Clinics of North America
M A Craigen, G C Bennet, J R MacKenzie, R Reid
We reviewed the records and radiographs of seven children who presented with knee pain, local tenderness over the medial femoral condyle, and radiological irregularity of the distal medial metaphysis of the femur suggestive of malignancy. In the five patients who had biopsies, histological changes were consistent with musculotendinous avulsion, and the dissection of ten cadavers confirmed the site to be the insertion of part of the adductor magnus. The recognition of this lesion and knowledge of its benign nature may avoid unnecessary anxiety and needless biopsy...
September 1994: Journal of Bone and Joint Surgery. British Volume
B Duerden, K W Bennet, J Faulkner
The introduction of an improved anaerobic system resulted in the isolation of Bacteroides ureolyticus (B corrodens) in numbers that suggested a pathogenic role from many more clinical specimens. During a three-year period B ureolyticus was isolated from 103 fairly superficial necrotic or gangrenous lesions all of which showed evidence of active infection. These included 27 perineal or genital infections, 15 perianal abscesses, 15 other soft tissue infections such as pilonidal abscesses and infected sebaceous cysts and 16 ulcers or gangrenous lesions of the lower limb...
March 1982: Journal of Clinical Pathology
G Lalande, C Diebler, A Grosvalet, G Ponsot, J M Bennet
Indications of CT examinations should be carefully established. Undisputed emergency indications in pediatric neurology are specified. Acute intracranial hypertension, whether isolated or associated with neurological signs or fever, is the principal emergency indication. Its main causes are posterior fossa tumors, but other space-occupying lesions may be found. The main radiological features in each etiology are described. Hemorrhage and trauma are the other essential emergency indications. Emergency CT examination can also be performed in unexplained coma...
September 8, 1983: La Semaine des Hôpitaux: Organe Fondé Par L'Association D'enseignement Médical des Hôpitaux de Paris
R Bennet, M Forsgren, P Herin
This report concerns a case of neonatal herpes zoster associated with maternal gestational varicella. The child developed skin lesions at 18 days of age virologically confirmed to be varicella-zoster. The baby also had encephalitis and aspiration probably due to bulbar paralysis. Multiple small necrotic areas were found in the thalamus at post-mortem examination.
November 1985: Acta Paediatrica Scandinavica
C Galakoff, G Kalifa, J Dubousset, J Bennet
Fourty-five children presenting with an isthmic lysis, complicated or not with spondylolisthesis were studied. The authors suggest that the isthmic lysis could be a stress-induced lesion, a "fatigue fracture" which may heal if treated early, before spondylolisthesis occurs. The main point is therefore an early diagnosis.
June 1985: Archives Françaises de Pédiatrie
B Paule, J Quillard, P Bennet, X Mariette, M Bisson
Thirty-five bone marrow biopsies were performed in 9 patients with plasmacytic/plasmablastic myeloma stage IIIA of the Durie and Salmon classification. The cytologic and/or histologic transformation observed in the serial bone marrow biopsy specimens of 3 patients reflected an aggravation of the disease, and was expressed as an increase of bone marrow plasmablasts associated with a gradual decrease or even disappearance of the plasmacytic component. Beyond 50% of bone marrow plasmablasts, the plasmablastic myeloma represented a more aggressive phase in the course of the disease...
1989: Nouvelle Revue Française D'hématologie
B M Johnston, P J Moore, L Bennet, M A Hanson, P D Gluckman
Almitrine bimesylate is a potent and long-lasting respiratory stimulant in adult species. It acts by stimulating the peripheral chemoreceptors, where it has been shown to accumulate specifically, although its exact mechanism of action is uncertain. In the fetal lamb, however, it produces a profound inhibition of breathing even after denervation of the peripheral chemoreceptors. In this respect its action is similar to hypoxia. To investigate whether almitrine is hypoxia mimetic, we examined the effect of almitrine in nine fetal lambs of 120-130 days gestation...
October 1990: Journal of Applied Physiology
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