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https://www.readbyqxmd.com/read/29149722/effects-of-middle-ear-quasi-static-stiffness-on-sound-transmission-quantified-by-a-novel-3-axis-optical-force-sensor
#1
Ivo Dobrev, Jae Hoon Sim, Baktash Aqtashi, Alexander M Huber, Thomas Linder, Christof Röösli
BACKGROUND: Intra-operative quantification of the ossicle mobility could provide valuable feedback for the current status of the patient's conductive hearing. However, current methods for evaluation of middle ear mobility are mostly limited to the surgeon's subjective impression through manual palpation of the ossicles. This study investigates how middle ear transfer function is affected by stapes quasi-static stiffness of the ossicular chain. The stiffness of the middle ear is induced by a) using a novel fiber-optic 3-axis force sensor to quantify the quasi-static stiffness of the middle ear, and b) by artificial reduction of stapes mobility due to drying of the middle ear...
November 10, 2017: Hearing Research
https://www.readbyqxmd.com/read/29133376/distinct-functions-of-starch-synthase-4-domains-in-starch-granule-formation
#2
Kuan-Jen Lu, Barbara Pfister, Camilla Jenny, Simona Eicke, Samuel C Zeeman
The formation of normal starch granules in Arabidopsis leaf chloroplasts requires STARCH SYNTHASE 4 (SS4). In plants lacking SS4, chloroplasts typically produce only one round granule rather than multiple lenticular granules. The mechanisms by which SS4 determines granule number and morphology are not understood. The N-terminal region of SS4 is unique among SS isoforms and contains several long coiled-coil motifs, typically implicated in protein-protein interactions. The C-terminal region contains the catalytic glucosyltransferase domains, which are widely conserved in plant SS and bacterial glycogen synthase (GS) isoforms...
November 13, 2017: Plant Physiology
https://www.readbyqxmd.com/read/29127310/wavefront-aberrations-and-retinal-image-quality-in-different-lenticular-opacity-types-and-densities
#3
Cheng-Zhe Wu, Hua Jin, Zhen-Nv Shen, Ying-Jun Li, Xun Cui
To investigate wavefront aberrations in the entire eye and in the internal optics (lens) and retinal image qualities according to different lenticular opacity types and densities. Forty-one eyes with nuclear cataract, 33 eyes with cortical cataract, and 29 eyes with posterior subcapsular cataract were examined. In each group, wavefront aberrations in the entire eye and in the internal optics and retinal image quality were measured using a raytracing aberrometer. Eyes with cortical cataracts showed significantly higher coma-like aberrations compared to the other two groups in both entire eye and internal optic aberrations (P = 0...
November 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29117419/secondary-lenticule-remnant-removal-after-smile
#4
Alex L K Ng, Peter S K Kwok, Tommy C Y Chan
PURPOSE: The authors report four cases of residual intrastromal lenticule after seemingly uneventful small incision lenticule extraction (SMILE) surgery and the outcome after a secondary procedure to remove the lenticule remnant. METHODS: Case reports. RESULTS: All four cases presented with suboptimal corrected distance visual acuity (CDVA) and refractive surprise. Irregularities in the corneal curvature and elevation were detected on corneal topography and tomography...
November 1, 2017: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/29117415/risk-factors-for-opaque-bubble-layer-in-small-incision-lenticule-extraction-smile
#5
Liuyang Li, Julie M Schallhorn, Jiaonan Ma, Lin Zhang, Rui Dou, Yan Wang
PURPOSE: To assess the independent effect of myopia and astigmatism on the risk of the occurrence of opaque bubble layer (OBL) in small incision lenticule extraction (SMILE) and further investigate the relationship between scanning depth and OBL. METHODS: Twenty-two cases and 317 controls were included in a case-control study from the database of Tianjin Eye Hospital from April 2015 to July 2016. Baseline characteristics were recorded and all of the eyes were manually reviewed by two different observers masked to preoperative refractive status...
November 1, 2017: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/29110086/acute-and-chronic-fluid-misdirection-syndrome-pathophysiology-and-treatment
#6
Andrzej Grzybowski, Piotr Kanclerz
PURPOSE: To summarize our current understanding of the specific pathogenic mechanisms of the fluid misdirection syndrome and possible treatment methods. METHODS: We used the PubMed web platform to find relevant studies using the following keywords: infusion misdirection syndrome, aqueous misdirection syndrome, ciliary block, ciliovitreal block, capsular block, intraoperative fluid misdirection, subcapsular fluid entrapment, acute intraoperative rock-hard eye syndrome, positive vitreous pressure glaucoma, and malignant glaucoma...
November 6, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/29102838/correlations-between-working-memory-impairment-and-neurometabolites-of-prefrontal-cortex-and-lenticular-nucleus-in-patients-with-major-depressive-disorder
#7
Yanyan Shan, Yanbin Jia, Shuming Zhong, Xueguo Li, Hui Zhao, Junhao Chen, Qianyi Lu, Lu Zhang, Zhinan Li, Shunkai Lai, Ying Wang
BACKGROUND: The mechanism of working memory (WM) impairment in MDD remains unclear. We aimed to find out the mechanism by using neuropsychological tests and proton magnetic resonance spectroscopy (1H-MRS). METHODS: 31 MDD patients and 31 healthy controls were recruited in our study. The WM performance and neurometabolite ratios of prefrontal cortex (PFC) and lenticular nucleus (LN) between two groups were evaluated and compared. And the correlations between abnormal neurometabolite ratios and WM dysfunction were computed...
October 28, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29099498/clinical-spectrum-and-surgical-outcomes-in-spherophakia-a-prospective-interventional-study
#8
S Khokhar, G Pillay, S Sen, E Agarwal
PurposeTo study the varied clinical presentations of patients with spherophakia, their management using surgical methods, and the clinical outcomes.Patients and methodsA prospective interventional study of 13 patients of spherophakia who presented to us from January 2014 and were followed up over the course of their treatment, and the data were documented for analysis.ResultsIn all, 26 eyes of 13 patients were reviewed and the median age of presentation was 12±12.05 years. All patients had a bilateral presentation with 22 eyes having lenticular myopia with a mean refractive error of -11...
November 3, 2017: Eye
https://www.readbyqxmd.com/read/29066071/altered-regional-and-circuit-resting-state-activity-in-patients-with-occult-spastic-diplegic-cerebral-palsy
#9
Xuetao Mu, Zhiqun Wang, Binbin Nie, Shaofeng Duan, Qiaozhi Ma, Guanghui Dai, Chunnan Wu, Yuru Dong, Baoci Shan, Lin Ma
BACKGROUND: Very few studies have been made to investigate functional activity changes in occult spastic diplegic cerebral palsy (SDCP). The purpose of this study was to analyze whole-brain resting state regional brain activity and functional connectivity (FC) changes in patients with SDCP. METHODS: We examined 12 occult SDCP and 14 healthy control subjects using resting-state functional magnetic resonance imaging. The data were analyzed using Resting-State fMRI Data Analysis Toolkit (REST) software...
October 7, 2017: Pediatrics and Neonatology
https://www.readbyqxmd.com/read/29053560/evaluation-of-human-corneal-lenticule-quality-after-smile-with-different-cap-thicknesses-using-scanning-electron-microscopy
#10
Shengbei Weng, Manli Liu, Xiaonan Yang, Fang Liu, Yugui Zhou, Haiqin Lin, Quan Liu
PURPOSE: To evaluate the surface characteristics of lenticules created by small-incision lenticule extraction (SMILE) with different cap thicknesses. METHODS: This prospective study included 20 consecutive patients who underwent bilateral SMILE. Surface regularity of the extracted corneal lenticule was analyzed using scanning electron microscopy (SEM) combined with 2 methods: qualitative and quantitative regularity. Qualitative regularity of SEM images was graded by masked observers using an established scoring system...
October 17, 2017: Cornea
https://www.readbyqxmd.com/read/29047503/subpixel-area-based-evaluation-for-crosstalk-suppression-in-quasi-three-dimensional-displays
#11
Zhenfeng Zhuang, Phil Surman, Qijia Cheng, Simon Thibault, Yuanjin Zheng, Xiao Wei Sun
A subpixel area-based evaluation method for an improved slanted lenticular film that minimizes the crosstalk in a quasi-three-dimensional (Q3D) display is proposed in this paper. To identify an optimal slant angle of the film, a subpixel area-based measurement is derived to evaluate the crosstalk among viewing regions of the intended subpixel and adjacent unintended subpixel by taking the real subpixel shape and black matrix into consideration. The subpixel mapping, which corresponds to the optimal slant angle of the film, can then be determined...
July 1, 2017: Applied Optics
https://www.readbyqxmd.com/read/28982612/brain-regional-iron-contents-in-progressive-supranuclear-palsy
#12
Seung Ha Lee, Chul Hyoung Lyoo, Sung Jun Ahn, Juha O Rinne, Myung Sik Lee
INTRODUCTION: To determine motor-related brain regions in which iron contents correlate with the degree of motor deficits of progressive supranuclear palsy (PSP). METHODS: Twenty-four patients with probable PSP and 20 controls were included. Using a 3.0T magnetic resonance imaging scanner, R2* values were measured in the putamen, globus pallidus (GP), substantia nigra (SN), subthalamic nucleus, and dentate nucleus. After adjustment for disease duration and age at examination, correlations between regional brain R2* values and Unified Parkinson Disease Rating Scale (UPDRS) total motor scores or subscores for bradykinesia, rigidity, tremor, or axial motor deficits were investigated...
September 28, 2017: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/28973367/imaging-lenticular-autofluorescence-in-older-subjects
#13
Jason Charng, Rose Tan, Chi D Luu, Sam Sadigh, Dwight Stambolian, Robyn H Guymer, Samuel G Jacobson, Artur V Cideciyan
Purpose: To evaluate whether a practical method of imaging lenticular autofluorescence (AF) can provide an individualized measure correlated with age-related lens yellowing in older subjects undergoing tests involving shorter wavelength lights. Methods: Lenticular AF was imaged with 488-nm excitation using a confocal scanning laser ophthalmoscope (cSLO) routinely used for retinal AF imaging. There were 75 older subjects (ages 47-87) at two sites; a small cohort of younger subjects served as controls...
October 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28969174/simultaneous-bilateral-anterior-and-posterior-lenticonus-in-alport-syndrome
#14
Ravi Kant Bamotra, Meenakshi, Prem Chandra Kesarwani, Shazia Qayum
Alport syndrome is an inherited disease characterized by progressive renal failure, hearing loss, and ocular abnormalities like anterior lenticonus, corneal opacities, cataract, central perimacular and peripheral coalescing fleck retinopathies, and temporal retinal thinning. Although anterior lenticonus is common in Alport syndrome, simultaneous anterior and posterior lenticonus is a rare presentation. We report a case of a 22-year-old female with simultaneous anterior and posterior lenticonus presentation in which ocular examination lead to the detection of Alport syndrome...
August 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28965668/hemorrhagic-infarct-of-basal-ganglia-in-cardiac-arrest-ct-and-mri-findings-2-cases
#15
Monique Boukobza, Frédéric J Baud
We report the CT and MRI findings in two cases of hemorrhagic infarct of the basal ganglia (BG), following out-of-hospital cardiac arrest (CA). In case 1, Brain-CT realized at day 2 showed bilateral and almost symmetric hemorrhagic infarct of the BG and infarct of the tectum of the mesencephalon. In case 2, MRI realized at day 6 showed hemorrhagic infarct of both lenticular nuclei on T2 GE images. In both cases there was no medical history and the cardiovascular and the coagulation profile were normal. In these cases, the lesions are observed earlier than reported in a few previous radiological cases...
September 21, 2017: Neurologia i Neurochirurgia Polska
https://www.readbyqxmd.com/read/28957056/2d-3d-switchable-display-based-on-a-passive-polymeric-lenticular-lens-array-and-electrically-suppressed-ferroelectric-liquid-crystal
#16
Liangyu Shi, Abhishek Kumar Srivastava, Alwin Ming Wai Tam, Vladimir Grigorievich Chigrinov, Hoi Sing Kwok
We reveal a 2D-3D switchable lens unit that is based on a polarization-sensitive microlens array and a polarization selector unit made of an electrically suppressed helix ferroelectric liquid crystal (ESHFLC) cell. The ESHFLCs offer a high contrast ratio (∼10k∶1) between the crossed polarizers at a low applied electric field (∼1.7  V/μm) with a small switching time (<50  μs). A special driving scheme, to switch between a 2D and 3D mode, has been developed to avoid unwanted issues related to DC accumulation in the ferroelectric liquid crystal without affecting its optical quality...
September 1, 2017: Optics Letters
https://www.readbyqxmd.com/read/28945628/improvements-to-phakometry-using-bessel-beams
#17
Marwan Suheimat, Dipesh Bhattarai, Hannah K Maher, Meera Chandra, William Chelepy, Sarah K Halloran, Andrew J Lambert, David A Atchison
SIGNIFICANCE: The main problem with phakometry is the low visibility of the third Purkinje image. We built a phakometer using Bessel beams, which have properties of being resistant to diffraction and the potential for self-reconstruction. This instrument had lenticular images three times brighter than those of a conventional phakometer. PURPOSE: To investigate Purkinje image brightness, accuracy, and repeatability of a "Bessel" phakometer compared with those of a conventional phakometer...
November 2017: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/28924416/detection-of-pars-plana-rupture-by-ultrasound-biomicroscopy-after-cannula-dislodgement-during-cataract-wound-hydration
#18
Yoshihiro Yonekawa, Benjamin J Thomas, Laurie K Lau-Sickon, Bradley J Anderson, Alan J Ruby
Ultrasound biomicroscopy (UBM) is a valuable diagnostic modality for imaging anterior ocular structures. Its utility has been well studied in anterior segment, lenticular, and pars plicata pathologies. However, imaging of the pars plana has been seldom described. We present the case of a 66-year-old woman referred for vitreous hemorrhage after expulsive cannula dislodgement into the posterior segment during wound hydration at the end of cataract surgery. B-scan ultrasonography initially detected a very anterior abnormality, but the resolution was insufficient for accurate diagnosis...
2017: Digital Journal of Ophthalmology: DJO
https://www.readbyqxmd.com/read/28905829/variation-in-the-vitreoretinal-configuration-of-stage-4-retinopathy-of-prematurity-in-photocoagulated-and-treatment-naive-eyes-undergoing-vitrectomy
#19
Salil Sharad Gadkari, Madan Deshpande
PURPOSE: We sought to document the difference in the vitreoretinal configuration of Stage 4 retinopathy of prematurity (ROP) in photocoagulated and treatment naive eyes undergoing vitrectomy and to correlate it with surgical complexity. METHODS: Consecutive eyes posted for vitrectomy with Stage 4 ROP were documented preoperatively using a RetCam for the presence of peripheral traction (PT), presence of central traction just outside the arcades, and presence of traction extending to the lens...
September 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28905827/refractive-and-ocular-biometric-profile-of-children-with-a-history-of-laser-treatment-for-retinopathy-of-prematurity
#20
Savleen Kaur, Jaspreet Sukhija, Deeksha Katoch, Mansi Sharma, Ramanuj Samanta, Mangat R Dogra
PURPOSE: Indian children belong to a diverse socioeconomic strata with retinopathy of prematurity (ROP) developing in mature, higher birth weight babies as well. The purpose of our study is to analyze the long-term status of refractive errors and its relationship with ocular biometry in children with ROP who were laser treated at a tertiary center in North India. METHODS: Cross sectional study. Children (<16 years) enrolled from January 2014 to December 2014 with a history of laser treatment for ROP and examined for refractive and biometric status...
September 2017: Indian Journal of Ophthalmology
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