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Yuichi Nishiyama, Hidekazu Kanayama, Hiroshi Mori, Keiji Tada, Yasushi Yamamoto, Takashi Katsube, Haruo Takeshita, Kazunori Kawakami, Hajime Kitagaki
OBJECTIVES: This study examined the usefulness of statistical parametric mapping (SPM) for investigating postmortem changes on brain computed tomography (CT). METHODS: This retrospective study included 128 patients (23 - 100 years old) without cerebral abnormalities who underwent unenhanced brain CT before and after death. The antemortem CT (AMCT) scans and postmortem CT (PMCT) scans were spatially normalized using our original brain CT template, and postmortem changes of CT values (in Hounsfield units; HU) were analysed by the SPM technique...
October 21, 2016: European Radiology
Rajesh Choudhary, Surendra H Bodakhe
AIMS: Previously we found that cadmium chloride (CdCl2) exposure substantially elevates hypertension and potentiates cataract formation. In the present study, we investigated the protective effects of olmesartan, an angiotensin II receptor blocker against cataractogenesis in the CdCl2-induced hypertensive animal model. MAIN METHODS: Male Sprague-Dawley albino rats (150-180g) were randomly selected and assigned to four groups (n=6). Among the four groups, one group (normal) received 0...
October 12, 2016: Life Sciences
Rajesh Choudhary, Surendra H Bodakhe
Previously we found that hypertension potentiates the risk the cataractogenesis. In the present study, we investigated the protective effects of magnesium taurate (MgT) on hypertension and associated lenticular damages against cadmium chloride (CdCl2)-induced hypertensive animals. Male Sprague-Dawley albino rats (150-180g) were assigned to five experimental groups (n=6). Among the five groups, normal group received 0.3% carboxymethyl cellulose (10ml/kg/day, p.o.). Hypertension control group received CdCl2 (0...
October 8, 2016: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
Jianzhang Hu, Jingjin Zhang, Yanling Li, Xiaoli Han, Weidong Zheng, Juan Yang, Guoxing Xu
Purpose. To evaluate the efficacy of a combination of intrastromal and intracameral injections of amphotericin B in the treatment of severe recalcitrant fungal keratitis. Methods. Patients with severe fungal keratitis who were resistant to conventional antifungal medical treatments and needed potential surgical intervention were recruited at the First Affiliated Hospital of Fujian Medical University between January 2012 and July 2013. The patients were treated with a combination of intrastromal and intracameral injections of amphotericin B (25 μg/mL and 50 μg/mL, resp...
2016: Journal of Ophthalmology
David A Atchison, Marwan Suheimat, Ankit Mathur, Lucas J Lister, Jos Rozema
Purpose: To determine the corneal surfaces and lens contributions to ocular aberrations. Methods: There were 61 healthy participants with ages ranging from 20 to 55 years and refractions -8.25 diopters (D) to +3.25 D. Anterior and posterior corneal topographies were obtained with an Oculus Pentacam, and ocular aberrations were obtained with an iTrace aberrometer. Raytracing through models of corneas provided total corneal and surface component aberrations for 5-mm-diameter pupils...
October 1, 2016: Investigative Ophthalmology & Visual Science
Soosan Jacob, Ashiyana Nariani, Michele Figus, Amar Agarwal, Athiya Agarwal
: We describe the white ring sign, which differentiates the posterior and anterior lenticular planes in small-incision lenticule extraction. The sign identifies the plane of dissection by the anteroposterior relationship between the dissecting instrument and the circular white light reflected from the lenticular side cut. Differentiating the planes enables the surgeon to dissect the anterior plane before the posterior plane, which facilitates smooth lenticule extraction and prevents complications such as cap tears, partial lenticule dissection, and a torn lenticule...
September 2016: Journal of Cataract and Refractive Surgery
Jie Hou, Yan Wang, Yulin Lei, Xiuyun Zheng, Ying Zhang
Purpose. To evaluate the changes in epithelial thickness profile following transepithelial photorefractive keratectomy (T-PRK) for myopia and to investigate the effect of epithelial remodeling on corneal asphericity. Methods. Forty-four patients (44 right eyes) who underwent T-PRK were retrospectively evaluated. Epithelial thickness was measured using spectral-domain optical coherence tomography at different corneal zones (central, 2 mm; paracentral, 2-5 mm; and mid-peripheral, 5-6 mm) preoperatively and at 1 week and 1, 3, and 6 months postoperatively...
2016: Journal of Ophthalmology
P Puz, A Lasek-Bal, P Radecka
BACKGROUND: Transcranial sonography may be applied to assess the basal ganglia nuclei and brain atrophy by the measurement of the width of the third ventricle. The aim of this study was to assess usefulness of transcranial sonography (TCS) in patients with multiple sclerosis (MS) by examining the echogenicity of subcortical structures and the width of the third ventricle. METHOD: Transcranial sonography evaluation of substantia nigra, brain stem raphe nuclei, diameter of the third ventricle, width of the anterior horn of the lateral ventricle, thalamus, lenticular nucleus, and head of the caudate nucleus in 41 patients with relapsing-remitting MS (RRMS), 23 with secondary progressive MS (SPMS), and 20 healthy controls was compared...
September 18, 2016: Acta Neurologica Scandinavica
Semra Acer, Gökhan Pekel, Vural Küçükatay, Aysun Karabulut, Ramazan Yağcı, Ebru Nevin Çetin, Şahika Pınar Akyer, Barbaros Şahin
PURPOSE: To evaluate lenticular oxidative stress in rat menopausal models. METHODS: Forty Wistar female albino rats were included in this study. A total of thirty rats underwent oophorectomy to generate a menopausal model. Ten rats that did not undergo oophorectomy formed the control group (Group 1). From the rats that underwent oophorectomy, 10 formed the menopause control group (Group 2), 10 were administered a daily injection of methylprednisolone until the end of the study (Group 3), and the remaining 10 rats were administered intraperitoneal streptozocin to induce diabetes mellitus (Group 4)...
July 2016: Arquivos Brasileiros de Oftalmologia
Sujata Subbiah, Philip A Thomas, C A Nelson Jesudasan
PURPOSE: To compare data on anatomical and biometric parameters, and their combination, obtained by using ultrasound biomicroscopy (UBM) and A-scan in eyes with phacomorphic glaucoma (PG) and eyes with mature cataract and to determine differences that may predispose to development of PG. METHODS: Eighty patients (80 eyes) were enrolled in this cross-sectional study. Anterior chamber parameters, namely anterior chamber depth (ACD), angle-opening distance (AOD), iris-lens contact distance (ILCD), and trabecular-ciliary process distance (TCPD), among other parameters, were assessed by UBM (35 MHz), while axial length (AL) and lenticular thickness (LT) were determined by A-scan biometry...
September 13, 2016: International Ophthalmology
Huan Wang, Ruidong Zhang, Shengzhou Zhang, Yongkang Zhou, Xiaobing Wu
In this study, the regional distribution and histological localization of somatostatin (SS) immunoreactive (IR) perikarya and fibers was investigated for the first time in the brain of adult Chinese alligator by immunohistochemical method. The results showed SS-IR perikarya and fibers were widely distributed in various parts of the brain except for olfactory bulbs. In the telencephalon, SS-IR perikarya were predominantly located in the cellular layer and deep plexiform layer of dorsomedial and medial cortex, less in the dorsal and lateral cortex, while SS-IR fibers were found in all layers of the cerebral cortex...
September 12, 2016: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
Oluwatoyin Helen Onakpoya, Caroline Olufunlayo Adeoti, Tunji Sunday Oluleye, Iyiade Adeseye Ajayi, Timothy Majengbasan, Olayemi Kolawole Olorundare
BACKGROUND: To review the visual status and clinical presentation of patients with retinitis pigmentosa (RP). METHODOLOGY: Multicenter, retrospective, and analytical review was conducted of the visual status and clinical characteristics of patients with RP at first presentation from January 2007 to December 2011. Main outcome measure was the World Health Organization's visual status classification in relation to sex and age at presentation. Data analysis by SPSS (version 15) and statistical significance was assumed at P<0...
2016: Clinical Ophthalmology
Yin Liu, Jun Liu, Huanghui Liu, Yunjie Liao, Lu Cao, Bin Ye, Wei Wang
OBJECTIVE: The aim of this study was to investigate focal iron deposition level in the brain in patients with ischemic cerebrovascular disease and its correlation with cerebral small vessel disease imaging markers. PATIENTS AND METHODS: Seventy-four patients with first-ever transient ischemic attack (median age: 69 years; 30 males and 44 females) and 77 patients with positive ischemic stroke history (median age: 72 years; 43 males and 34 females) were studied retrospectively...
2016: Therapeutics and Clinical Risk Management
Si Zhang, Guopeng Liang, Yan Ju, Chao You
BACKGROUND: and object: Pediatric basal ganglia germ cell tumors (GCTs) represent a rare subset of tumors with poor understandings. We aimed to summarize the clinical features and radiological findings of this special subgroup of GCTs. METHODS: From January 2010 to January 2015, twelve pediatric patients suffered from basal ganglia GCTs were treated in our hospital. The clinical features, radiological findings, diagnosis, treatment and outcome of these patients were retrospectively analyzed...
August 24, 2016: World Neurosurgery
P Schmieder, D Denysenko, M Grzywa, O Magdysyuk, D Volkmer
The novel metal-organic framework CFA-8 (Coordination Framework Augsburg University-8), [Cu2(tqpt)], containing the organic linker H2-tqpt {H2-tqpt = 6,6,14,14-tetramethyl-6,14-dihydroquinoxalino[2,3-b]phenazinebis-triazole}, has been synthesized. Reaction of H2-tqpt and anhydrous CuCl2 in N,N-dimethylacetamide (DMA) yields CFA-8 as orange crystals with lenticular shape. This framework shows a reversible breathing effect and is robust upon solvent removal. It has been characterized by single-crystal and powder X-ray diffraction, TGA, IR spectroscopy and gas sorption measurements...
September 21, 2016: Dalton Transactions: An International Journal of Inorganic Chemistry
Meng-Wan Yeh, J Gregory Shellnutt
The break-up of Pangæa was principally facilitated by tensional plate stress acting on pre-existing suture zones. The rifting of Pangæa began during the Early Permian along the southern Tethys margin and produced the lenticular-shaped continent known as Cimmeria. A mantle-plume model is ascribed to explain the rift-related volcanism but the NW-SE oriented Cimmerian rifts do not correlate well with pre-existing suture zones or 'structural heterogeneities' but appear to have a pertinent spatial and temporal association with Late Palæozoic glacial-interglacial cycles...
2016: Scientific Reports
Duo Chen, Xinzhu Sang, Xunbo Yu, Zhidong Chen, Peng Wang, Xin Gao, Nan Guo, Songlin Xie
Autostereoscopic printing is one of the most common ways for three-dimensional display, because it can present finer results by printing higher dots per inches (DPI). However, there are some problems for current methods. First, errors caused by dislocation between integer grids and non-customized lenticular lens result in severe vision quality. Second, the view-number and gray-level cannot be set arbitrarily. In this paper, an improved halftoning method for autostereoscopic printing based on float grid-division multiplexing (fGDM) is proposed...
August 8, 2016: Optics Express
Casper F Andersen, Graham D Finlayson, David Connah
Estimation of individual spectral cone fundamentals from color-matching functions is a classical and longstanding problem in color science. In this paper we propose a novel method to carry out this estimation based on a linear optimization technique, employing an assumption of a priori knowledge of the retinal absorptance functions. The result is an estimation of the combined lenticular and macular filtration for an individual, along with the nine coefficients in the linear combination that relates their color-matching functions to their estimated spectral-cone fundamentals...
August 1, 2016: Journal of the Optical Society of America. A, Optics, Image Science, and Vision
Jayshree Shriram Dawane, Vijaya Anil Pandit, Swapnil Suryakant Deshpande, Amruta Sumedh Mandpe
INTRODUCTION: Diabetes is a metabolic disease of vital health importance because of the complications associated with it. Clinical trials and animal studies have demonstrated the anti-hyperglycaemic effect of Nishamalaki. Present study was planned to evaluate the protective potential of Nishamalaki on diabetic complication in rats. AIM: To study the Nephro-protective effect and to assess the protective potential on retinal changes of Nishamalaki in diabetic wistar rats...
June 2016: Journal of Clinical and Diagnostic Research: JCDR
Sajjad Javadi, Reza Yousefi, Saman Hosseinkhani, Ali-Mohammad Tamaddon, Vladimir N Uversky
The high level of dehydroascorbic acid (DHA) in the lenticular tissue is an important risk factor for the development of age-related cataracts. In this study, the effects of DHA on structure and function of lens crystallins were studied in the presence of carnosine using gel mobility shift assay, different spectroscopic techniques, and lens culture analysis. The DHA-induced unfolding and aggregation of lens proteins were largely prevented by this endogenous dipeptide. The ability of carnosine to preserve native protein structure upon exposure to DHA suggests the essential role of this dipeptide in prevention of the senile cataract development...
July 29, 2016: Journal of Biomolecular Structure & Dynamics
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