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PET IN CHILDREN

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https://www.readbyqxmd.com/read/28623811/residential-exposure-to-pesticides-as-risk-factor-for-childhood-and-young-adult-brain-tumors-a-systematic-review-and-meta-analysis
#1
REVIEW
Geneviève Van Maele-Fabry, Laurence Gamet-Payrastre, Dominique Lison
BACKGROUND: Accumulating evidence suggests a positive association between exposure to non-agricultural pesticides and childhood brain tumors (CBT). OBJECTIVE: (1) To conduct a systematic review and meta-analysis of published studies on the association between residential/household/domestic exposure to pesticides and childhood brain tumors. (2) To clarify variables that could impact the results. METHODS: Publications in English were identified from a MEDLINE search through 28 February 2017 and from the reference list of identified publications...
June 14, 2017: Environment International
https://www.readbyqxmd.com/read/28622851/prevalence-and-zoonotic-risks-of-trichophyton-mentagrophytes-and-cheyletiella-spp-in-guinea-pigs-and-rabbits-in-dutch-pet-shops
#2
P A M Overgaauw, K H A van Avermaete, C A R M Mertens, M Meijer, N J Schoemaker
Young rabbits and guinea pigs are often purchased as pets for children and may be infected with zoonotic skin infections. To assess the risk of acquiring such an infection from rabbits or guinea pigs, this study investigated the prevalence of the fungus Trichophyton mentagrophytes and the fur mite Cheyletiella parasitovorax in asymptomatic rabbits and guinea pigs in Dutch pet shops. In 91 pet shops a total of 213 rabbits and 179 guinea pigs were sampled using the Mackenzie technique and cultured. Clean cultures were examined microscopically and a PCR was performed on at least one sample from each pet shop...
June 2017: Veterinary Microbiology
https://www.readbyqxmd.com/read/28616694/-dermophytes-and-guinea-pigs-an-underestimated-danger
#3
C Kupsch, M Berlin, Y Gräser
BACKGROUND: For several years, an increasing number of human infections, mainly affecting children, with the zoophilic dermatophyte Trichophyton benhamiae has been observed. It is predominantly transmitted by pet guinea pigs. The prevalence of the dermatophyte on guinea pigs which are for sale in pet shops is unknown. OBJECTIVE: Therefore, the aim of this study was to analyze the frequency of T. benhamiae on symptomatic and asymptomatic guinea pigs from pet shops in Berlin...
June 14, 2017: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/28615758/regional-cerebral-glucose-metabolism-and-its-association-with-phenotype-and-cognitive-functioning-in-patients-with-autism
#4
B N Anil Kumar, Savita Malhotra, Anish Bhattacharya, Sandeep Grover, Y K Batra
INTRODUCTION: In spite of three decades of neuroimaging, we are unable to find consistent and coherent anatomical or pathophysiological basis for autism as changes are subtle and there are no studies from India. AIM: To study the regional cerebral glucose metabolism in children with autism using positron emission tomography (PET) scan and to study the behavior and cognitive functioning among them. MATERIALS AND METHODS: Ten subjects (8-19 years) meeting Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition criteria for autism were evaluated on Childhood Autism Rating Scale (CARS), trail making test (TMT) A and B, Wisconsin card sorting test, Raven's progressive matrices, and PET scan...
May 2017: Indian Journal of Psychological Medicine
https://www.readbyqxmd.com/read/28613428/prenatal-and-postnatal-exposure-to-pet-ownership-and-lung-function-in-children-the-seven-northeastern-cities-study
#5
Li-Wen Hu, Zhengmin Qian, Shyamali C Dharmage, Echu Liu, Steven W Howard, Michael G Vaughn, Jennifer Perret, Caroline C Lodge, Xiao-Wen Zeng, Bo-Yi Yang, Shu-Li Xu, Chuan Zhang, Guang-Hui Dong
To evaluate the association between prenatal and postnatal exposure to pet ownership and lung function in children, a cross-sectional study named Seven Northeastern Cities (SNEC) study was conducted. In this study, children's lung function including the forced expiratory volume in 1 second (FEV1 ), forced vital capacity (FVC), maximal mid-expiratory flow (MMEF), peak expiratory flow (PEF) were measured by spirometers, and pet ownership situations was collected by questionnaire. Analyzed by multiple logistic regression and generalized linear modeling, we found that for all subjects, pet exposure in the first 2 years of life was significantly associated with lung function impairment of FVC<85% predicted (adjusted odds ratio [aOR]=1...
June 14, 2017: Indoor Air
https://www.readbyqxmd.com/read/28611957/genetic-virulence-profile-of-enteroaggregative-escherichia-coli-strains-isolated-from-danish-children-with-either-acute-or-persistent-diarrhea
#6
Betina Hebbelstrup Jensen, Anja Poulsen, Stig Hebbelstrup Rye Rasmussen, Carsten Struve, Jørgen H Engberg, Alice Friis-Møller, Nadia Boisen, Rie Jønsson, Randi F Petersen, Andreas M Petersen, Karen A Krogfelt
Enteroaggregative Escherichia coli (EAEC) is frequently found in diarrheal stools worldwide. It has been associated with persistent diarrhea, weight loss, and failure to thrive in children living in developing countries. A number of important EAEC virulence genes are identified; however, their roles in acute and persistent diarrhea have not been previously investigated. The aim of this study was to identify specific EAEC virulence genes associated with duration and type of diarrhea in Danish children. We aimed to improve the current diagnostics of EAEC and enable targeting of strains with an expected severe disease course...
2017: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/28604476/pet-mr-in-the-assessment-of-pediatric-histiocytoses-a-comparison-to-pet-ct
#7
Andrew C Sher, Robert Orth, Kenneth McClain, Carl Allen, Shireen Hayatghaibi, Victor Seghers
PURPOSE: The aim of this study was to analyze the feasibility and diagnostic performance of F-FDG PET/MR compared with F-FDG PET/CT in a cohort of pediatric histiocytosis patients with regard to image quality, lesion detection, and FDG quantification. METHODS: Children with a diagnosis of Langerhans cell histiocytosis or Rosai-Dorfman disease were prospectively recruited. Seventeen PET/CT and PET/MR examinations were performed on 9 patients (mean age, 6.2 years) following a single-injection dual-imaging protocol...
June 9, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28601683/prenatal-intrapartum-and-postnatal-factors-are-associated-with-pediatric-eosinophilic-esophagitis
#8
Elizabeth T Jensen, Jonathan T Kuhl, Lisa J Martin, Marc E Rothenberg, Evan S Dellon
BACKGROUND: Multiple lines of evidence point to the potential importance of early-life environmental factors in the rapid rise in incidence of eosinophilic esophagitis (EoE), but potential exposures have not been extensively studied. OBJECTIVE: To assess the association between prenatal, intrapartum, and postnatal factors and the development of pediatric EoE using a case-control study. METHODS: Cases of EoE were recruited from an existing registry at Cincinnati Children's Hospital Medical Center (CCHMC)...
June 7, 2017: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28601174/thoracic-neoplasms-in-children-contemporary-perspectives-and-imaging-assessment
#9
REVIEW
Matthew A Zapala, Victor M Ho-Fung, Edward Y Lee
This article focuses on commonly encountered primary lung, airway, mediastinal, and chest wall neoplasms that occur in the pediatric population. Although primary pediatric thoracic neoplasms are rare, imaging is critical in their diagnostic work-up. An overview of the latest imaging techniques specific to evaluate these pediatric thoracic neoplasms is presented across the spectrum of modalities from radiography to PET/MR imaging. In addition, the characteristic imaging appearances of these pediatric primary thoracic neoplasms are discussed with an emphasis on what the radiologist needs to know in routine clinical practice...
July 2017: Radiologic Clinics of North America
https://www.readbyqxmd.com/read/28583503/prevalence-of-pressure-equalization-tube-placement-and-hearing-loss-in-children-with-down-syndrome
#10
Gisele F Bernardi, Carolina T F Pires, Nanci P Oliveira, Renato Nisihara
OBJECTIVE: To determine the prevalence of pressure equalization tube (PET) placement and hearing loss in children with Down syndrome (DS). MATERIAL AND METHODS: We evaluated 90 DS children births between 1 and 11 years old and compared to 90 children without DS paired in sex and age. Medical records were analyzed consecutively. Were collected data about proceedings PET placement, age of the patient at each PET, adenoidectomy, tonsillectomy and results for audiometry and tympanometry...
July 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28567298/recurrent-insulinoma-in-a-10-year-old-boy-with-down-s-syndrome
#11
Noman Ahmad, Abdulmonem Mohammed Almutawa, Mohamed Ziyad Abubacker, Hossam Ahmed Elzeftawy, Osama Abdullah Bawazir
An insulinoma is a rare tumour with an incidence of four cases per million per year in adults. The incidence in children is not established. There is limited literature available in children with insulinoma, and only one case is reported in association with Down's syndrome in adults. Insulinoma diagnosis is frequently missed in adults as well as in children. The Whipple triad is the most striking feature although it has limited application in young children. Hypoglycaemia with elevated insulin, C-peptide and absent ketones is highly suggestive of hyperinsulinism...
2017: Endocrinology, Diabetes & Metabolism Case Reports
https://www.readbyqxmd.com/read/28560222/a-birth-cohort-analysis-to-study-dog-walking-in-adolescence-shows-no-relationship-with-objectively-measured-physical-activity
#12
Carri Westgarth, Andrew R Ness, Calum Mattocks, Robert M Christley
Physical inactivity during childhood and adolescence is a serious health concern. There are few studies of the activity undertaken by adolescents when walking with the family dog, and the effect of this on objectively measured physical activity levels. Objective measures of physical activity using accelerometers were recorded at age 11-12, 13-14, and 15-16 years in the Avon Longitudinal Study of Parents and Children (ALSPAC) (ALSPAC, UK) birth cohort during the 2000s. Family pet ownership was collected retrospectively using a questionnaire at age 18 years, for the ages 7, 11, 13, and 15 years...
2017: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/28545900/environmental-contamination-with-toxocara-spp-eggs-in-public-parks-and-playground-sandpits-of-greater-lisbon-portugal
#13
David Otero, Ana Margarida Alho, Rolf Nijsse, Jeroen Roelfsema, Paul Overgaauw, Luís Madeira de Carvalho
Toxocarosis is a zoonotic parasitic disease transmitted from companion animals to humans. Environmental contamination with Toxocara eggs is considered to be the main source of human infections. In Portugal, knowledge regarding the current situation, including density, distribution and environmental contamination by Toxocara spp., is largely unknown. The present study investigated environmental contamination with Toxocara spp. eggs, in soil and faecal samples collected from public parks and playground sandpits in Greater Lisbon, Portugal...
May 22, 2017: Journal of Infection and Public Health
https://www.readbyqxmd.com/read/28544629/household-pet-exposure-allergic-sensitization-and-rhinitis-in-the-u-s-population
#14
Josef Shargorodsky, Esther Garcia-Esquinas, Rachel Umanskiy, Ana Navas-Acien, Sandra Y Lin
BACKGROUND: The effect of animal dander exposure on allergic sensitization may be age-dependent. A comparison between the association of the levels of exposure to pet allergen with rhinitis symptoms and allergic sensitization in children and adults is yet to be performed in the U.S. POPULATION: HASH(0x3dbd7b0) METHODS: Cross-sectional study of 3034 adults (age, 20 to 85 years) and 2104 children (age, 6 to 19 years) in the National Health and Nutrition Examination Survey, 2005-2006...
May 25, 2017: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/28534182/imaging-children-suffering-from-lymphoma-an-evaluation-of-different-18-f-fdg-pet-mri-protocols-compared-to-whole-body-dw-mri
#15
Julian Kirchner, Cornelius Deuschl, Bernd Schweiger, Ken Herrmann, Michael Forsting, Christian Buchbender, Gerald Antoch, Lale Umutlu
OBJECTIVES: The objectives of this study were to evaluate and compare the diagnostic potential of different PET/MRI reading protocols, entailing non-enhanced / contrast-enhanced and diffusion-weighted (18)F-FDG PET/MR imaging and whole-body diffusion-weighted MRI for lesion detection and determination of the tumor stage in pediatric lymphoma patients. METHODS: A total of 28 (18)F-FDG PET/MRI datasets were included for analysis of four different reading protocols: (1) PET/MRI utilizing sole unenhanced T2w and T1w imaging, (2) PET/MRI utilizing additional contrast enhanced sequences, (3) PET/MR imaging utilizing unenhanced, contrast enhanced and DW imaging or (4) WB-DW-MRI...
May 22, 2017: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/28512714/comparison-of-the-diagnostic-accuracy-of-pet-mri-to-pet-ct-acquired-fdg-brain-exams-for-seizure-focus-detection-a-prospective-study
#16
Michael J Paldino, Erica Yang, Jeremy Y Jones, Nadia Mahmood, Andrew Sher, Wei Zhang, Shireen Hayatghaibi, Ramkumar Krishnamurthy, Victor Seghers
BACKGROUND: There is great interest in positron emission tomography (PET)/magnetic resonance (MR) as a clinical tool due to its capacity to provide diverse diagnostic information in a single exam. OBJECTIVE: The goal of this exam is to compare the diagnostic accuracy of PET/MR-acquired [F-18]2-fluoro-2-deoxyglucose (FDG) brain exams to that of PET/CT with respect to identifying seizure foci in children with localization-related epilepsy. MATERIALS AND METHODS: Institutional Review Board approval and informed consent were obtained for this Health Insurance Portability and Accountability Act-compliant, prospective study...
May 16, 2017: Pediatric Radiology
https://www.readbyqxmd.com/read/28508606/surgery-in-focal-congenital-hyperinsulinism-chi-the-hyperinsulinism-germany-international-experience-in-30-children
#17
Winfried Barthlen, Emine Varol, Susann Empting, Ilse Wieland, Martin Zenker, Wolfgang Mohnike, Silke Vogelgesang, Klaus Mohnike
OBJECTIVES: Results of surgery for focal CHI in 30 children PATIENTS AND METHODS: All showed an ABCC8 or KCNJ11 mutation. After PET/CT in 29 children and PET/MRT in 1 case, frozen-section guided resection was performed, in left-sided cases by laparoscopy. Mean age at surgery was 11.7 months (2-49). RESULTS: In 28/30 children, the PET/CT or MRT correlated with histopathology. In two cases, a focal lesion was undectable; one of these was cured, one not. In total, 24 children showed lesions with sizes of 5-12 mm...
December 2016: Pediatric Endocrinology Reviews: PER
https://www.readbyqxmd.com/read/28495911/intratumoral-injection-of-hsv1716-an-oncolytic-herpes-virus-is-safe-and-shows-evidence-of-immune-response-and-viral-replication-in-young-cancer-patients
#18
Keri A Streby, James I Geller, Mark A Currier, Patrick S Warren, John M Racadio, Alexander J Towbin, Michele R Vaughan, Melinda Triplet, Kristy Ott-Napier, Devon J Dishman, Lori R Backus, Beth Stockman, Marianne Brunner, Kathleen Simpson, Robert Spavin, Joe Conner, Timothy P Cripe
Purpose: HSV1716 is an oncolytic herpes simplex virus-1 (HSV-1) studied in adults via injection into the brain and superficial tumors. To determine the safety of administering HSV1716 to pediatric patients with cancer, we conducted a phase I trial of image-guided injection in young patients with relapsed or refractory extracranial cancers.Experimental Design: We delivered a single dose of 10(5) to 10(7) infectious units of HSV1716 via computed tomography-guided intratumoral injection and measured tumor responses by imaging...
May 11, 2017: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
https://www.readbyqxmd.com/read/28491488/dog-attachment-and-perceived-social-support-in-overweight-obese-and-healthy-weight-children
#19
Deborah E Linder, Jennifer M Sacheck, Farzad Noubary, Miriam E Nelson, Lisa M Freeman
The development of effective and sustainable interventions to treat childhood obesity remains both a priority and a challenge. Previous studies support that dogs provide social support in overweight adults in obesity interventions, but the child-dog relationship is not as well understood. The goal of the study was to examine the child-dog relationship among children to inform novel childhood obesity interventions including dogs. A cross-sectional study was conducted in the Living Laboratory® at the Museum of Science, Boston in 2015...
June 2017: Preventive Medicine Reports
https://www.readbyqxmd.com/read/28490281/beyond-recovery
#20
Paul W C Wong, Kenny C T Lau, Lucia L Liu, Gloria S N Yuen, Poon Wing-Lok
It is a worldwide trend that more households are having pets or companion animals. Hence, there has been an increasing number of animal lovers experience companion animal loss bereavement. This form of bereavement has not been explored in Chinese societies. We conducted a qualitative study using in-depth interviews with 31 animal lovers and recruited through convenience and snowball sampling in Hong Kong. Companion animal loss bereavement appears to share similar features to other forms of bereavement but also has its unique features...
June 2017: Omega
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