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PET IN CHILDREN

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https://www.readbyqxmd.com/read/28094612/student-essays
#1
Krista Barzee
I am proud to say I qualified in adult nursing this year with a 2:1 degree. I managed to achieve this while caring for two children and various pets and working part-time.
January 4, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28081128/radiation-exposure-from-diagnostic-imaging-in-a-cohort-of-pediatric-transplant-recipients
#2
Alexandra Seal, Michael Hawkes, Ravi Bhargava, Michelle Noga, Jutta Preiksaitis, Curtis Mabilangan, Joan Robinson
Recipients of solid organ transplants (SOT) have extensive diagnostic imaging (DI). The purpose of this study was to quantify this exposure. Children from northern Alberta with SOTs at Stollery Children's Hospital, Edmonton, Alberta January 1, 2006, to July 31, 2012, were included. Effective doses of radiation were estimated using published norms for DI performed post-transplant up to October 16, 2014. The 54 eligible children had 6215 DI studies (5628 plain films, 293 computerized tomography (CT) scans, 149 positron emission topography (PET) -CT scans, 47 nuclear medicine scans and 98 cardiac catheterizations)...
2017: PloS One
https://www.readbyqxmd.com/read/28078638/-11-c-methionine-positron-emission-tomography-delineates-non-contrast-enhancing-tumor-regions-at-high-risk-for-recurrence-in-pediatric-high-grade-glioma
#3
John T Lucas, Nick Serrano, Hyun Kim, Xingyu Li, Scott E Snyder, Scott Hwang, Yimei Li, Chia-Ho Hua, Alberto Broniscer, Thomas E Merchant, Barry L Shulkin
We assessed the prognostic utility of (11)C-Methionine positron emission tomography (MET-PET) in pediatric high-grade glioma (HGG). Thirty-one children had 62 MET-PET studies. Segmented tumor volumes from co-registered magnetic resonance studies were assessed for concordance with MET-PET uptake using Boolean operations. The tumor volume at diagnosis and treatment failure was assessed relative to MET-PET avid volume. The prognostic impact of MET-PET-delineated non-contrast enhancing tumor (NCET) was assessed...
January 11, 2017: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/28077260/third-party-social-evaluations-of-humans-by-monkeys-and-dogs
#4
REVIEW
James R Anderson, Benoit Bucher, Hitomi Chijiiwa, Hika Kuroshima, Ayaka Takimoto, Kazuo Fujita
Developmental psychologists are increasingly interested in young children's evaluations of individuals based on third-party interactions. Studies have shown that infants react negatively to agents who display harmful intentions toward others, and to those who behave unfairly. We describe experimental studies of capuchin monkeys' and pet dogs' differential reactions to people who are helpful or unhelpful in third-party contexts, and monkeys' responses to people who behave unfairly in exchanges of objects with a third party...
January 7, 2017: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/28070151/imaging-of-glutamate-concentration-in-sturge-weber-syndrome
#5
COMMENT
Tracy S Gertler, Cynthia V Stack
Investigators from Wayne State University studied a cohort of children with Sturge-Weber syndrome (SWS) and epilepsy using both glucose-based positron emission tomography (FDG-PET) to evaluate metabolic activity and proton magnetic resonance spectroscopic imaging (MRSI) to evaluate glutamate turnover.
January 2017: Pediatric neurology briefs
https://www.readbyqxmd.com/read/28040805/dynamic-contrast-enhanced-magnetic-resonance-imaging-dce-mri-combined-with-positron-emission-tomography-computed-tomography-pet-ct-and-video-electroencephalography-veeg-have-excellent-diagnostic-value-in-preoperative-localization-of-epileptic-foci-in-children
#6
Gui-Bin Wang, Wei Long, Xiao-Dong Li, Guang-Yin Xu, Ji-Xiang Lu
BACKGROUND To investigate the effect that dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) has on surgical decision making relative to video-electroencephalography (VEEG) and positron emission tomography-computed tomography (PET-CT), and if the differences in these variables translates to differences in surgical outcomes. MATERIAL AND METHODS A total of 166 children with epilepsy undergoing preoperative DCE-MRI, VEEG, and PET-CT examinations, surgical resection of epileptic foci, and intraoperative electrocorticography (ECoG) monitoring were enrolled...
January 1, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28036050/environmental-determinants-of-bronchial-asthma-among-saudi-school-children-in-southwestern-saudi-arabia
#7
Jobran M Alqahtani, Ahmed M Asaad, Nabil J Awadalla, Ahmed A Mahfouz
The aim here was to study the possible environmental and dietary determinants of asthma among school-aged children in Southwestern Saudi Arabia. In a cross-sectional study on a representative sample in Najran in Southwestern Saudi Arabia using an Arabic version of the modified ISAAC Phase III, parent-administered questionnaire data were collected. Skin prick tests (SPTs) were performed. The study included 1700 school children, out of them 468 (27.5%) were diagnosed with, cases of bronchial asthma and 20.8% (353) reported a 12-month nocturnal cough (as a proxy of severe asthma)...
December 28, 2016: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28028401/the-prevalence-of-allergic-rhinitis-eczema-and-asthma-in-students-of-guidance-schools-in-mazandaran-province-iran
#8
Daniel Zamanfar, Javad Gaffari, Salar Behzadnia, Jamshid Yazdani-Charati, Sahar Tavakoli
BACKGROUND: Eczema, allergic rhinitis and asthma are common chronic allergic disorders in childhood. AIM: The aim of this study was to determine the prevalence of common allergic disorders among Iranian guidance schools students in Mazandaran Province, northern Iran. METHODS: This analytical cross-sectional study was performed on 3000 children aged 11-14 years old during 2012-13 according to ISAAC study. Of 3000 recruited children 1576 (52...
December 15, 2016: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28026209/correlation-of-pet-ct-and-image-guided-biopsies-of-pediatric-malignancies
#9
Saeed Nihayah, Amer Shammas, Reza Vali, Dimitri Parra, Sarah Alexander, Joao Amaral, Bairbre Connolly
OBJECTIVE: The purpose of this study was to evaluate an early experience with correlation of PET/CT findings and image-guided biopsy results in pediatric patients. MATERIALS AND METHODS: In a single-center retrospective case series, the inclusion criterion was performance of image-guided biopsy within 6 weeks of PET/CT, either before or after the biopsy. RESULTS: Forty-five patients (23 boys, 22 girls; age range, 4-17 years; median, 10.5 years; weight range, 14...
December 27, 2016: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28005698/prenatal-and-postnatal-exposure-to-pet-ownership-blood-pressure-and-hypertension-in-children-the-seven-northeastern-cities-study
#10
Shu-Li Xu, Edwin Trevathan, Zhengmin Qian, Elaina Vivian, Bo-Yi Yang, Li-Wen Hu, Xiao-Wen Zeng, Meng Li, Yang Zhou, Xiao-Di Qin, Wen-Wen Bao, Ping Yuan, Ya-Zhi Zhang, Jia Wang, Chuan Zhang, Yan-Peng Tian, Min Nian, Xiang Xiao, Guang-Hui Dong
OBJECTIVE: There is little information about how exposure to pets impacts blood pressure (BP) in children. The objective of the present study was to investigate the association between pet exposure and BP in children. METHODS: A total of 9354 children, aged 5-17 years, from 24 elementary schools and 24 middle schools in the Seven Northeastern Cities were evaluated during 2012-2013. BP measurements were taken using a mercury sphygmomanometer. Hypertension in children was defined as having an average DBP or SBP in the 95th percentile or higher for the child's sex, age, and height...
February 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/27992253/farm-fairs-and-petting-zoos-a-review-of-animal-contact-as-a-source-of-zoonotic-enteric-disease
#11
Cheyenne C Conrad, Kim Stanford, Claudia Narvaez-Bravo, Todd Callaway, Tim McAllister
Many public venues such as farms, fairs, and petting zoos encourage animal contact for both educational and entertainment purposes. However, healthy farm animals, including cattle, small ruminants, and poultry, can be reservoirs for enteric zoonotic pathogens, with human infections resulting in nausea, vomiting, diarrhea, and, in some cases, severe complications that can lead to death. As animals shed these organisms in their feces, contamination of themselves and their surroundings is unavoidable. The majority of North Americans reside in urban and suburban settings, and the general public often possess limited knowledge of agricultural practices and minimal contact with farm animals...
December 19, 2016: Foodborne Pathogens and Disease
https://www.readbyqxmd.com/read/27942901/laparoscopic-partial-splenectomy-for-unknown-primary-cancer-a-stepwise-approach
#12
Eduardo A Vega, Suguru Yamashita, Chun Yun Shin, Michael Kim, Jason B Fleming, Mathew H Katz, Kanwal P S Raghav, Jean-Nicolas Vauthey, Jeffrey E Lee, Claudius Conrad
BACKGROUND: Laparoscopic partial splenectomy (LPS) for focal splenic lesions is technically demanding and carries risk of hemorrhage. Nevertheless, it can be a valuable option, particularly for children and adults in whom attempt at preservation of splenic immunologic function outweighs risk associated with organ preservation. PATIENT: A 58-year-old man was diagnosed with a focal splenic lesion at the upper splenic pole on surveillance imaging following axillary lymph node metastasis for cancer of unknown primary origin (CUP)...
December 9, 2016: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/27940791/indoor-environmental-control-practices-and-asthma-management
#13
Elizabeth C Matsui, Stuart L Abramson, Megan T Sandel
Indoor environmental exposures, particularly allergens and pollutants, are major contributors to asthma morbidity in children; environmental control practices aimed at reducing these exposures are an integral component of asthma management. Some individually tailored environmental control practices that have been shown to reduce asthma symptoms and exacerbations are similar in efficacy and cost to controller medications. As a part of developing tailored strategies regarding environmental control measures, an environmental history can be obtained to evaluate the key indoor environmental exposures that are known to trigger asthma symptoms and exacerbations, including both indoor pollutants and allergens...
November 2016: Pediatrics
https://www.readbyqxmd.com/read/27939465/antiretrovirals-causing-severe-pre-eclampsia
#14
Lloyd Tooke, Linda Riemer, Mushi Matjila, Michael Harrison
BACKGROUND: Extremely low birth weight infants (ELBW) (⩽1000g) at our tertiary hospital have a much higher HIV exposure rate than bigger babies and are mainly delivered due to complications of pre-eclampsia. Studies investigating the effect of HIV or antiretroviral therapy on pre-eclampsia, a partially immune-mediated disease have produced contradictory results. OBJECTIVE: To determine if there was an association between pre-eclampsia and HIV and/or antiretrovirals in the mothers of ELBW infants...
October 2016: Pregnancy Hypertension
https://www.readbyqxmd.com/read/27935825/microglia-activation-in-a-pediatric-rabbit-model-of-tuberculous-meningitis
#15
Elizabeth W Tucker, Supriya Pokkali, Zhi Zhang, Vincent P DeMarco, Mariah Klunk, Elizabeth S Smith, Alvaro A Ordonez, Marie-France Penet, Zaver Bhujwalla, Sanjay K Jain, Sujatha Kannan
Central nervous system (CNS) tuberculosis (TB) is the most severe form of extra-pulmonary TB and disproportionately affects young children where the developing brain has a unique host response. New Zealand white rabbits were infected with Mycobacterium tuberculosis via subarachnoid inoculation at postnatal day 4-8 and evaluated until 4-6 weeks post-infection. Control and infected rabbit kits were assessed for the development of neurological deficits, bacterial burden, and postmortem microbiologic and pathologic changes...
December 1, 2016: Disease Models & Mechanisms
https://www.readbyqxmd.com/read/27931290/hygiene-factors-associated-with-childhood-food-allergy-and-asthma
#16
Ruchi S Gupta, Anne Marie Singh, Madeline Walkner, Deanna Caruso, Paul J Bryce, Xiaobin Wang, Jacqueline A Pongracic, Bridget M Smith
BACKGROUND: Childhood food allergy and asthma rates are increasing. The hygiene hypothesis has been proposed as an explanation for the increased incidence of allergic disease. OBJECTIVE: To describe the association of childhood food allergy and asthma with hygiene factors, such as the number of siblings, antibiotic use, infection history, pet exposure, child care exposure, and maternalchild factors. METHODS: Children ages 021 years old (N = 1359) were recruited for a cross-sectional family-based study, including children with food allergy and children without food allergy, and their siblings...
November 2016: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/27915035/hyperinsulinaemic-hypoglycaemia-in-children-and-adults
#17
REVIEW
Pratik Shah, Sofia A Rahman, Huseyin Demirbilek, Maria Güemes, Khalid Hussain
Pancreatic β cells are functionally programmed to release insulin in response to changes in plasma glucose concentration. Insulin secretion is precisely regulated so that, under normal physiological conditions, fasting plasma glucose concentrations are kept within a narrow range of 3·5-5·5 mmol/L. In hyperinsulinaemic hypoglycaemia, insulin secretion becomes dysregulated (ie, uncoupled from glucose metabolism) so that insulin secretion persists in the presence of low plasma glucose concentrations. Hyperinsulinaemic hypoglycaemia is the most common cause of severe and persistent hypoglycaemia in neonates and children...
November 30, 2016: Lancet Diabetes & Endocrinology
https://www.readbyqxmd.com/read/27898257/assessment-of-nifedipine-therapy-in-hyperinsulinemic-hypoglycemia-due-to-mutations-in-the-abcc8-gene
#18
M Güemes, P Shah, S Silvera, K Morgan, C Gilbert, L Hinchey, K Hussain
CONTEXT: Previous case reports have documented the effectiveness of L-type calcium channel blockers (such as Nifedipine and Verapamil) for treating different forms of hyperinsulinemic hypoglycemia (HH). OBJECTIVE: To systematically assess the glycemic response to Nifedipine therapy in 11 patients with HH due to mutations in the ABCC8 gene. DESIGN: Dose escalation of Nifedipine therapy Setting: Inpatients at a tertiary hospital Patients or Other Participants: 11 children with diazoxide unresponsive HH due to mutations in the ABCC8 gene...
November 29, 2016: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27886218/revisiting-the-fear-of-snakes-in-children-the-role-of-aposematic-signalling
#19
Jérémie Souchet, Fabien Aubret
Why humans fear snakes is an old, yet unresolved debate. Its innate origin from evolutionary causes is debated against the powerful influence early experience, culture, media and religion may have on people's aversion to snakes. Here we show that the aversion to snakes in human beings may have been mistaken for an aversion to aposematic signals that are commonly displayed by snakes. A total of 635 children were asked to rate single item images as "nice" or "mean". Snakes, pets and smiley emoticon items were not rated as "mean" unless they displayed subtle aposematic signals in the form of triangular (rather than round) shapes...
November 25, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27861990/contact-sensitization-in-dutch-children-and-adolescents-with-and-without-atopic-dermatitis%C3%A2-%C3%A2-a-retrospective-analysis
#20
Stefanie Lubbes, Thomas Rustemeyer, Johannes H Sillevis Smitt, Marie-Louise A Schuttelaar, Maritza A Middelkamp-Hup
BACKGROUND: Allergic contact dermatitis is known to occur in children with and without atopic dermatitis, but more data are needed on contact sensitization profiles in these two groups. OBJECTIVES: To identify frequent allergens in children with and without atopic dermatitis suspected of having allergic contact dermatitis. METHODS: A retrospective analysis of children aged 0-17 years patch tested between 1996 and 2013 was performed. RESULTS: Of all 1012 children tested because of suspected contact dermatitis, 46% developed one or more positive reactions, the proportions for children with (n = 526) and without (n = 395) atopic dermatitis being 48% and 47%, respectively...
November 11, 2016: Contact Dermatitis
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