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developmental regression

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https://www.readbyqxmd.com/read/29668045/when-does-the-influence-of-maturation-on-anthropometric-and-physical-fitness-characteristics-increase-and-subside
#1
Christopher Towlson, Stephen Cobley, Guy Parkin, Ric Lovell
The relationships between maturation and anthropometric and physical performance characteristics are dynamic and often asynchronous; confounding the capability to accurately evaluate performance during adolescence. This study aimed to (i) examine the influence of chronological age (CA) and somatic maturation (YPHV) upon anthropometric and physical performance parameters, and (ii) identify the transition/change time-points in these relationships using segmental regression. N=969 soccer players (8-18 years of age) completed anthropometric and physical test assessments, including a counter-movement jump (CMJ), agility T-test, 10 and 20m sprints, and multi-stage fitness test (MSFT)...
April 18, 2018: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/29664993/scaling-relationships-and-vessel-packing-in-petioles
#2
Dustin M Ray, Cynthia S Jones
PREMISE OF THE STUDY: While tradeoffs among mechanical and conductive functions have been well investigated in woody stems, these tradeoffs are relatively unexplored in petioles, the structural link between stems and laminas. We investigated size-independent scaling relationships between cross-sectional areas of structural and vascular tissues, relationships between tissue areas of xylem and phloem, vessel packing within xylem, and scaling of vascular and structural tissues with lamina traits...
April 17, 2018: American Journal of Botany
https://www.readbyqxmd.com/read/29663621/neurodevelopmental-outcomes-of-young-children-born-to-hiv-positive-mothers-in-rural-yunnan-china
#3
Jie Wu, Jing Li, Yan Li, Kek Khee Loo, Haixia Yang, Qiong Wang, Rufei Duan, Xia Xiao, Xiaoxiao Song, Siwei Yang, Lin Sun
BACKGROUND: Children born to HIV-infected mothers are at risk for neurodevelopmental delay. Little is known about neurodevelopmental outcomes of infants and toddlers who were born to HIV-positive mothers but were not themselves infected by HIV, especially in poor rural areas. This study was conducted to compare developmental outcomes between young children who were HIV-exposed but uninfected (HEU) and their HIV-unexposed and uninfected (HUU) peers in rural Yunnan, China. METHODS: A total of 250 HEU children aged 6-36 months and 250 HUU children matched on age, gender and residency were recruited from rural Yunnan, China...
April 16, 2018: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/29659656/sexual-risk-taking-and-subcortical-brain-volume-in-adolescence
#4
Sarah W Feldstein Ewing, Karen A Hudson, Justin Caouette, Andrew R Mayer, Rachel E Thayer, Sephira G Ryman, Angela D Bryan
Background : The developmental period of adolescence marks the initiation of new socioemotional and physical behaviors, including sexual intercourse. However, little is known about neurodevelopmental influences on adolescent sexual decision-making. Purpose: We sought to determine how subcortical brain volume correlated with condom use, and whether those associations differed by gender and pubertal development. Methods: We used FreeSurfer to extract subcortical volume among N = 169 sexually experienced youth (mean age 16...
April 6, 2018: Annals of Behavioral Medicine: a Publication of the Society of Behavioral Medicine
https://www.readbyqxmd.com/read/29659350/does-dental-caries-affect-dental-development-in-children-and-adolescents
#5
Brunilda Dhamo, Besiana Elezi, Lea Kragt, Eppo B Wolvius, Edwin M Ongkosuwito
Although a link between dietary changes, caries, and dental development has been observed, the literature provides little insight about this relationship. The aim of our study was to investigate the association between dental caries and dental development in a clinical sample of Albanian children and adolescents. In total, 118 children and adolescents, born between 1995 and 2004 and aged 6-15 years, were included. Dental caries in the deciduous dentition was assessed using the Decayed, Filled Teeth (dft) index and dental caries in the permanent dentition was assessed using the Decayed, Missing, Filled Teeth (DMFT) index...
April 6, 2018: Bosnian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/29656285/sociocultural-and-familial-factors-associated-with-weight-bias-internalization
#6
Rebecca L Pearl, Thomas A Wadden, Jena Shaw Tronieri, Ariana M Chao, Naji Alamuddin, Zayna M Bakizada, Emilie Pinkasavage, Robert I Berkowitz
BACKGROUND/AIMS: Sociocultural and familial factors associated with weight bias internalization (WBI) are currently unknown. The present study explored the relationship between interpersonal sources of weight stigma, family weight history, and WBI. METHODS: Participants with obesity (N = 178, 87.6% female, 71.3% black) completed questionnaires that assessed the frequency with which they experienced weight stigma from various interpersonal sources. Participants also reported the weight status of their family members and completed measures of WBI, depression, and demographics...
April 14, 2018: Obesity Facts
https://www.readbyqxmd.com/read/29649520/development-and-validation-of-a-prognostic-score-to-predict-tuberculosis-mortality
#7
Duc T M Nguyen, Edward A Graviss
OBJECTIVE: To develop and validate a simple prognostic scoring system to predict the mortality risk during treatment in tuberculosis patients. METHODS: Using data from the CDC's Tuberculosis Genotyping Information Management System of TB patients in Texas reported from 01/2010 to 12/2016, age ≥ 15 years and having an outcome as "completed" or "died", we developed and validated a prognostic mortality scoring system-based logistic regression beta-coefficients...
April 9, 2018: Journal of Infection
https://www.readbyqxmd.com/read/29626662/can-early-life-growth-disruptions-predict-longevity-testing-the-association-between-vertebral-neural-canal-vnc-size-and-age-at-death
#8
Alexandra Amoroso, Susana J Garcia
This study tests the association of vertebral neural canal (VNC) size and age-at-death in a Portuguese skeletal collection from the 19th -20th century. If the plasticity and constraint model best explains this association, VNC size would be negatively related to mortality risk. If the predictive adaptive response (PAR) model is a better fit, no association can be inferred between VNC size and age-at-death. Ninety individuals were used in this study. The anteroposterior and transverse diameters of all vertebrae were measured...
April 4, 2018: International Journal of Paleopathology
https://www.readbyqxmd.com/read/29625363/off-label-use-and-manipulations-of-antiepileptic-drugs-in-children-analysis-of-the-outpatient-prescriptions-in-a-tertiary-center
#9
Mathieu Kuchenbuch, Nicole Chemaly, Kassem Mb Henniene, Anna Kaminska, Catherine Chiron, Rima Nabbout
OBJECTIVES: Little is known about off-label use and manipulations to achieve the prescribed dose of antiepileptic drugs (AEDs) in outpatient prescriptions. This study aimed to evaluate this practice in a tertiary center for child epilepsy. METHODS: We reviewed off-label use and manipulations of AEDs delivered to the outpatient's epilepsy clinic. Multivariate logistic regressions were used to determine the factors associated with off-label and manipulated uses. RESULTS: Five hundred eleven consultations generated 897 AED deliveries (1...
April 3, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29624924/brief-report-poor-self-regulation-as-a-predictor-of-individual-differences-in-adaptive-functioning-in-young-children-with-autism-spectrum-disorder
#10
Mirko Uljarević, Darren Hedley, Rose Nevill, David W Evans, Ru Ying Cai, Eric Butter, James A Mulick
The present study examined the link between poor self-regulation (measured by the child behavior checklist dysregulated profile [DP]) and core autism symptoms, as well as with developmental level, in a sample of 107 children with autism spectrum disorder (ASD) aged 19-46 months. We further examined the utility of DP in predicting individual differences in adaptive functioning, relative to the influence of ASD severity, chronological age (CA), and developmental level. Poor self-regulation was unrelated to CA, developmental level, and severity of ADOS-2 restricted and repetitive behaviors, but was associated with lower ADOS-2 social affect severity...
April 6, 2018: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/29621731/relationship-between-maternal-exposure-to-bisphenol-s-and-pregnancy-duration
#11
Yanjian Wan, Wenqian Huo, Shunqing Xu, Tongzhang Zheng, Bin Zhang, Yuanyuan Li, Aifen Zhou, Yiming Zhang, Jie Hu, Yingshuang Zhu, Zhong Chen, Shi Lu, Chuansha Wu, Minmin Jiang, Yangqian Jiang, Hongxiu Liu, Xueyu Yang, Wei Xia
Bisphenol S (BPS) has been progressively used due to the potential safety problems of bisphenol A (BPA). Thus Human studies are needed to investigate the developmental effects of BPS. In this study, the impact of maternal BPS exposure on birth outcomes was evaluated with linear and logistic regression models. BPS was analyzed in spot urine samples collected from 985 pregnant women at admission to labor. It was found in 93.7% of the urine samples with the specific gravity adjusted geometric mean concentration of 0...
April 2, 2018: Environmental Pollution
https://www.readbyqxmd.com/read/29620388/using-linked-data-to-investigate-developmental-vulnerabilities-in-children-of-convicted-parents
#12
Megan F Bell, Donna M Bayliss, Rebecca Glauert, Jeneva L Ohan
There is evidence that children of incarcerated parents are at risk of poor developmental and educational outcomes. However, much of this evidence is limited by biased samples, as studies must rely on opt-in recruitment. Administrative data present an opportunity to overcome this challenge, as they capture information on all incarcerated individuals. This study used administrative data on convictions of the parents of 19,071 children aged 5-6 years in Western Australia. Records of parental convictions (starting from 1 year prior to the child's birth) were linked to children's scores on the Australian Early Development Census, which is a teacher-reported measure of children's physical, social, emotional, communicative, and cognitive development...
April 5, 2018: Developmental Psychology
https://www.readbyqxmd.com/read/29618764/temporal-trends-and-developmental-patterns-of-plasma-polybrominated-diphenyl-ether-concentrations-over-a-15-year-period-between-1998-and-2013
#13
Whitney J Cowell, Andreas Sjödin, Richard Jones, Ya Wang, Shuang Wang, Julie B Herbstman
Polybrominated diphenyl ethers (PBDEs) were used extensively as flame retardants in furniture containing polyurethane foam until they were phased out of use, beginning in 2004. We examined temporal changes in plasma PBDE concentrations from 1998 to 2013 and characterized patterns of exposure over the early lifecourse among 334 children (903 samples) between birth and 9 years. We examined time trends by regressing PBDE concentration on year of sample collection in age-adjusted models and characterized developmental trajectories using latent class growth analysis (LCGA)...
April 4, 2018: Journal of Exposure Science & Environmental Epidemiology
https://www.readbyqxmd.com/read/29618326/a-novel-homozygous-mutation-in-polr3a-gene-causing-4h-syndrome-a-case-report
#14
Vishal V Tewari, Ritu Mehta, C M Sreedhar, Kunal Tewari, Akbar Mohammad, Neerja Gupta, Sheffali Gulati, Madhulika Kabra
BACKGROUND: 4H syndrome is a congenital hypomyelinating leukodystrophy characterized by hypodontia, hypomyelination and hypogonadotropic hypogonadism belonging to the Pol III-related leukodystrophies which arise due to mutations in the POLR3A or POLR3B gene. The clinical presentation is of neurodevelopmental delay or regression with ataxia, dystonia, nystagmus, delayed deciduous dentition and abnormal order of eruption of teeth. MRI brain shows a characteristic hypomyelination pattern...
April 4, 2018: BMC Pediatrics
https://www.readbyqxmd.com/read/29618308/genetics-and-therapies-for-gm2-gangliosidosis
#15
María Begona Cachon-Gonzalez, Eva Zaccariotto, Timothy Martin Cox
Tay-Sachs disease, caused by impaired β-N-acetylhexosaminidase activity, was the first GM2 gangliosidosis to be studied and one of the most severe and earliest lysosomal diseases to be described. The condition, associated with the pathological build-up of GM2 ganglioside, has acquired almost iconic status and serves as a paradigm in the study of lysosomal storage diseases. Inherited as a classical autosomal recessive disorder, this global disease of the nervous system induces developmental arrest with regression of attained milestones; neurodegeneration progresses rapidly to cause premature death in young children...
April 4, 2018: Current Gene Therapy
https://www.readbyqxmd.com/read/29617366/cross-sectional-associations-of-screen-time-and-outdoor-play-with-social-skills-in-preschool-children
#16
Trina Hinkley, Helen Brown, Valerie Carson, Megan Teychenne
Screen time and physical activity behaviours develop during the crucial early childhood period (0-5 years) and impact multiple health and developmental outcomes, including psychosocial wellbeing. Social skills, one component of psychosocial wellbeing, are vital for children's school readiness and future mental health. This study investigates potential associations of screen time and outdoor play (as a proxy for physical activity) with social skills. Cross sectional data were available for 575 mothers with a child (54% boys) aged 2-5 years...
2018: PloS One
https://www.readbyqxmd.com/read/29616380/culture-and-the-trajectories-of-developmental-pathology-insights-from-control-and-information-theories
#17
Rodrick Wallace
Cognition in living entities-and their social groupings or institutional artifacts-is necessarily as complicated as their embedding environments, which, for humans, includes a particularly rich cultural milieu. The asymptotic limit theorems of information and control theories permit construction of a new class of empirical 'regression-like' statistical models for cognitive developmental processes, their dynamics, and modes of dysfunction. Such models may, as have their simpler analogs, prove useful in the study and re-mediation of cognitive failure at and across the scales and levels of organization that constitute and drive the phenomena of life...
April 3, 2018: Acta Biotheoretica
https://www.readbyqxmd.com/read/29616204/parent-communication-prompt-to-increase-shared-decision-making-a-new-intervention-approach
#18
Lauren M Hubner, Heidi M Feldman, Lynne C Huffman
Objective: Shared decision-making (SDM) is the process by which patients, clinicians, and in pediatrics, parents/caregivers, discuss treatment options, communicate available evidence for or against the different options, share preferences and values, and eventually arrive at a joint decision. This study evaluates the use of a novel, universally applicable, SDM intervention, provided to parents, intended to promote engagement and participation with their child's clinician. Methods: Two-arm randomized controlled trial comparing the impact of a SDM-focused intervention prompt to a neutral comparison prompt on perception of SDM participation...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/29615950/personality-influences-the-relationship-between-primary-emotions-and-religious-spiritual-well-being
#19
Michaela Hiebler-Ragger, Jürgen Fuchshuber, Heidrun Dröscher, Christian Vajda, Andreas Fink, Human F Unterrainer
The study of human emotions and personality provides valuable insights into the parameters of mental health and well-being. Affective neuroscience proposes that several levels of emotions - ranging from primary ones such as LUST or FEAR up to higher emotions such as spirituality - interact on a neural level. The present study aimed to further explore this theory. Furthermore, we hypothesized that personality - formed by bottom-up primary emotions and cortical top-down regulation - might act as a link between primary emotions and religious/spiritual well-being...
2018: Frontiers in Psychology
https://www.readbyqxmd.com/read/29610408/family-characteristics-and-children-s-receipt-of-autism-services-in-low-resourced-families
#20
Elizabeth A Karp, Rebecca Dudovitz, Bergen B Nelson, Wendy Shih, Amanda Gulsrud, Felice Orlich, Costanza Colombi, Alice A Kuo
OBJECTIVES: Parents of children with autism spectrum disorder (ASD) face competing demands when caring for their child and fulfilling family commitments. It remains unknown whether family obligations and parental stress might decrease the use of intervention services for young children with ASD. METHODS: The current study is a secondary analysis of baseline date from a published randomized control trial with 147 low-resourced caregiver-child dyads. Demographic information, data on service use, maternal employment, parent's perception of their child's development, and parental stress were collected for primary caregivers of 2- to 5-year-old children with ASD from 5 sites...
April 2018: Pediatrics
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