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developmental regression

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https://www.readbyqxmd.com/read/28229835/-neurodevelopmental-outcomes-of-very-preterm-or-very-low-birth-weigth-infants-comparison-of-monochorionic-and-dichorionic-twins-with-singletons
#1
Adelaide Taborda, Guiomar Oliveira
INTRODUCTION: Twins are associated with a delayed development and cerebral palsy. The purpose of this work was to compare the neurologic morbidity in very preterm or very low birth weight dichorionic and monochorionic twins with singletons. MATERIAL AND METHODS: We conducted a retrospective cohort study of livebirths lowest through 32 weeks of gestation or very low weight infants admitted to Neonatal Intensive Care Unit of a level III hospital, between 2006 and 2010...
November 2016: Acta Médica Portuguesa
https://www.readbyqxmd.com/read/28220358/potential-risk-factors-for-the-development-of-self-injurious-behavior-among-infants-at-risk-for-autism-spectrum-disorder
#2
Adele F Dimian, Kelly N Botteron, Stephen R Dager, Jed T Elison, Annette M Estes, John R Pruett, Robert T Schultz, Lonnie Zwaigenbaum, Joseph Piven, Jason J Wolff
Prevalence of self-injurious behavior (SIB) is as high as 50% among children with autism spectrum disorder (ASD). Identification of risk factors for the development of SIB is critical to early intervention and prevention. However, there is little empirical research utilizing a prospective design to identify early risk factors for SIB. The purpose of this study was to evaluate behavioral characteristics predicting SIB at age 2 years among 235 infants at high familial risk for ASD. Logistic regression results indicated that presence of SIB or proto-SIB and lower developmental functioning at age 12 months significantly predicted SIB at 24 months...
February 20, 2017: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/28217937/evidence-for-the-association-of-hashimoto-s-thyroiditis-with-psoriasis-a-cross-sectional-retrospective-study
#3
Tina Kiguradze, Finola M Bruins, Nicholas Guido, Tanya Bhattacharya, Alfred Rademaker, Aleksandra G Florek, Alba Posligua, Shatil Amin, Anne E Laumann, Dennis P West, Beatrice Nardone
BACKGROUND: Current information indicates that psoriasis is a metabolic disorder with systemic manifestations. Reports have revealed an association between psoriasis and several chronic autoimmune disorders. For one of these disorders, Hashimoto's thyroiditis (HT), there are scarce, and relatively unconfirmed, reports of an association with psoriasis. We sought to determine if such an association is detectable in a large medical record data repository. METHODS: We searched one institution's electronic medical record data repository from January 2010 to December 2013...
February 19, 2017: International Journal of Dermatology
https://www.readbyqxmd.com/read/28217150/infantile-tremor-syndrome-a-review-and-critical-appraisal-of-its-etiology
#4
REVIEW
Jatinder Singh Goraya, Sukhjot Kaur
Infantile tremor syndrome (ITS) is defined by the tetrad of pallor, developmental delay/regression, skin pigmentation, and brown scanty scalp hair. Involuntary movements in the form of tremors supervene in the natural course of the illness in a significant number of cases. The disorder occurs in exclusively breast-fed infants of vegetarian mothers belonging to economically deprived sections of society. Most of the children eventually recover but are frequently left with long-term cognitive and language neurodeficits...
October 2016: Journal of Pediatric Neurosciences
https://www.readbyqxmd.com/read/28208690/examining-the-relationship-between-economic-hardship-and-child-maltreatment-using-data-from-the-ontario-incidence-study-of-reported-child-abuse-and-neglect-2013-ois-2013
#5
Rachael Lefebvre, Barbara Fallon, Melissa Van Wert, Joanne Filippelli
There is strong evidence that poverty and economic disadvantage are associated with child maltreatment; however, research in this area is underdeveloped in Canada. The purpose of this paper is to examine the relationship between economic hardship and maltreatment for families and children identified to the Ontario child protection system for a maltreatment concern. Secondary analyses of the Ontario Incidence Study of Reported Child Abuse and Neglect-2013 (OIS-2013) were conducted. The OIS-2013 examines the incidence of reported maltreatment and the characteristics of children and families investigated by child welfare authorities in Ontario in 2013...
February 8, 2017: Behavioral Sciences
https://www.readbyqxmd.com/read/28204921/the-impact-of-parental-offending-on-offspring-aggression-in-early-childhood-a-population-based-record-linkage-study
#6
Stacy Tzoumakis, Kimberlie Dean, Melissa J Green, Catherine Zheng, Maina Kariuki, Felicity Harris, Vaughan J Carr, Kristin R Laurens
PURPOSE: To examine the impact of parental criminal offending, both paternal and maternal, on offspring aggression at age 5 years, while also considering key risk factors, including parental mental illness, child's sex, and socioeconomic disadvantage. METHODS: The sample comprised 69,116 children, with linked parental information, from the New South Wales Child Development Study, a population-based multi-agency, multi-generational record linkage study that combines information from a teacher-reported cross-sectional survey of early childhood development at age 5 years (the 2009 Australian Early Development Census; AEDC) with data obtained via administrative records from multiple sources (e...
February 15, 2017: Social Psychiatry and Psychiatric Epidemiology
https://www.readbyqxmd.com/read/28203332/status-and-determinants-of-motor-impairment-in-preschool-children-from-migrant-families-in-china
#7
Hua Jin, Jing Hua, Jianqiang Shen, Lijuan Feng, Guixiong Gu
BACKGROUND: Although poor health conditions and decreased developmental levels have been investigated in migrant children, no study in China has focused on these children's individual motor development. OBJECTIVES: This study aims to explore the prevalence of motor impairment in Chinese migrant children and to determine the contributory factors. PATIENTS AND METHODS: In this cross-sectional study, a structured questionnaire was administered to primary caregivers of preschool children aged 3 - 6 (n = 2,976) in ten kindergartens from two districts of Suzhou, China, to assess the children's home socioeconomic status and motor environment, that is, the presence of affordances for motor development...
October 2016: Iranian Journal of Pediatrics
https://www.readbyqxmd.com/read/28192818/-benefits-of-measures-to-promote-development-in-language-mathematics-and-singing-in-kindergardeners-analysis-of-data-collected-at-school-entrance-examination-in-the-county-of-biberach
#8
Ulrike Hart, Manfred Wildner, Daniela Krämer, Alexander Crispin
To evaluate the benefits of implementing measures to promote skills in the areas of language, mathematics and singing in kindergardeners by statistical analysis of data collected during the school entrance examination (ESU) of 4-5-year-old children from the county of Biberach. Study 1 employs multivariate regression analysis to analyse - in chronological order - the ESU data on 4 cohorts (2011-2014; n=7 148) of children of the Biberach county. Study 2 qualitatively compares identical data representative of the entire state of Baden-Württemberg (N=3×80 000) with the Biberach results...
February 13, 2017: Das Gesundheitswesen
https://www.readbyqxmd.com/read/28188591/shell-fluctuating-asymmetry-in-the-sea-dwelling-benthic-bivalve-mytilus-galloprovincialis-lamarck-1819-as-morphological-markers-to-detect-environmental-chemical-contamination
#9
Massimiliano Scalici, Lorenzo Traversetti, Federica Spani, Valentina Malafoglia, Monica Colamartino, Tiziana Persichini, Simone Cappello, Giuseppe Mancini, Giulia Guerriero, Marco Colasanti
Investigations on asymmetries showed that deviations from perfect bilateral symmetry are interpreted as environmental changes inducing developmental instability. Since morphological abnormalities increase with pollution, deformations may be considered indicators of the organism exposition to pollution. Therefore, the onset of asymmetry in otherwise normally symmetrical traits has been used as a measure of some stresses as well. In this context, we studied how marine pollution affects the valve morphological alterations in the mussel Mytilus galloprovincialis...
February 10, 2017: Ecotoxicology
https://www.readbyqxmd.com/read/28185945/age-related-volumetric-change-of-limbic-structures-and-subclinical-anxious-depressed-symptomatology-in-typically-developing-children-and-adolescents
#10
Matthew D Albaugh, Tuong-Vi Nguyen, Simon Ducharme, D Louis Collins, Kelly N Botteron, Nicholas D'Alberto, Alan C Evans, Sherif Karama, James J Hudziak
OBJECTIVE: To investigate the extent to which subclinical variation in anxious/depressed psychopathology is associated with volume and age-related volumetric change of limbic structures in a longitudinal sample of healthy youths. METHODS: Linear mixed-effects models were used to analyze longitudinal behavioral and neuroimaging data (up to 3 data points per subject, collected at 2 year-intervals) in 371 typically developing youths, from 4 to 18 years of age (196 females; 723 MRIs)...
February 7, 2017: Biological Psychology
https://www.readbyqxmd.com/read/28183286/register-based-study-of-the-incidence-comorbidities-and-demographics-of-obsessive-compulsive-disorder-in-specialist-healthcare
#11
Hanna Rintala, Roshan Chudal, Sami Leppämäki, Susanna Leivonen, Susanna Hinkka-Yli-Salomäki, Andre Sourander
BACKGROUND: Incidence of obsessive-compulsive disorder (OCD) has been suspected to increase but nationwide epidemiological studies are limited. This study aims to examine sex-specific incidence time trends and characterize psychiatric and neurodevelopmental comorbidities and sociodemographic risk factors of OCD in specialist healthcare in Finland. METHODS: A nationwide register-based study using data from four Finnish registers identified 3372 OCD cases and 13,372 matched controls (1:4)...
February 10, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28182458/combined-evaluations-of-competency-to-stand-trial-and-mental-state-at-the-time-of-the-offense-an-overlooked-methodological-consideration
#12
Lauren Kois, James M Wellbeloved-Stone, Preeti Chauhan, Janet I Warren
Combined evaluations of competency to stand trial (CST; competency) and mental state at the time of the offense (MSO; sanity) frequently co-occur. However, most research examines the 2 as discrete constructs without considering 4 potential combined evaluation outcomes: competent-sane, incompetent-sane, competent-insane, and incompetent-insane. External validity can be improved if research more closely mirrored practice. It may be incorrect to assume incompetent defendants are similar across CST-only and combined evaluations, and insane defendants are similar across MSO-only and combined evaluations...
February 9, 2017: Law and Human Behavior
https://www.readbyqxmd.com/read/28182449/the-family-environment-in-early-childhood-has-a-long-term-effect-on-self-esteem-a-longitudinal-study-from-birth-to-age-27-years
#13
Ulrich Orth
A better understanding is needed of the factors that shape the development of individual differences in self-esteem. Using a prospective longitudinal design, this research tested whether the family environment in early childhood predicts self-esteem in later developmental periods. Data came from a nationally representative U.S. sample of 8,711 participants, who reported on their self-esteem biannually from age 8 to 27 years. Moreover, during the participants' first 6 years of life, biannual assessments of their mothers provided information on the quality of the home environment (covering quality of parenting, cognitive stimulation, and physical home environment), quality of parental relationship, presence of father, maternal depression, and poverty status of the family...
February 9, 2017: Journal of Personality and Social Psychology
https://www.readbyqxmd.com/read/28177185/effect-of-bronchopulmonary-dysplasia-on-the-early-intellectual-development-of-preterm-infants
#14
Fatao Lin, Haipeng Dong, Yanyan Song, Tengwei Zhang, Junye Qi, Xuwen Xiao, Yueju Cai
OBJECTIVE: This study aimed to explore the effect of bronchopulmonary dysplasia (BPD) on the early intellectual development of preterm infants. METHODS: From 2011 to 2015, 83 preterm infants diagnosed with BPD were recruited to the BPD group, and 89 preterm infants without BPD and 98 healthy term infants were randomly recruited to the non-BPD and term group, respectively. Neural and intellectual development according to the Gesell Development Scale were evaluated and compared between groups at 0-3 months, 3-6 months, 6-9 months, and 9-12 months of adjusted age for preterm infants and real age for term infants...
February 8, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28166369/heterozygous-truncation-mutations-of-the-smc1a-gene-cause-a-severe-early-onset-epilepsy-with-cluster-seizures-in-females-detailed-phenotyping-of-10-new-cases
#15
Joseph D Symonds, Shelagh Joss, Kay A Metcalfe, Suresh Somarathi, Jamie Cruden, Anita M Devlin, Alan Donaldson, Nataliya DiDonato, David Fitzpatrick, Frank J Kaiser, Anne K Lampe, Melissa M Lees, Ailsa McLellan, Tara Montgomery, Vivek Mundada, Lesley Nairn, Ajoy Sarkar, Jens Schallner, Jelena Pozojevic, Ilaria Parenti, Jeen Tan, Peter Turnpenny, William P Whitehouse, Sameer M Zuberi
OBJECTIVE: The phenotype of seizure clustering with febrile illnesses in infancy/early childhood is well recognized. To date the only genetic epilepsy consistently associated with this phenotype is PCDH19, an X-linked disorder restricted to females, and males with mosaicism. The SMC1A gene, which encodes a structural component of the cohesin complex is also located on the X chromosome. Missense variants and small in-frame deletions of SMC1A cause approximately 5% of Cornelia de Lange Syndrome (CdLS)...
February 6, 2017: Epilepsia
https://www.readbyqxmd.com/read/28165594/usefulness-of-measuring-acetabular-anterior-coverage-using-a-tomosynthesis-imaging-system
#16
Tadahiko Ohtsuru, Yasuyuki Morita, Yuhei Horiuchi, Yasuaki Murata, Shuji Shimamoto, Yuji Morita, Yutaro Munakata, Yoshiharu Kato
PURPOSE: The purpose of this study was to compare the usefulness of measuring acetabular anterior coverage by tomosynthesis and false profile (FP) radiography. METHODS: 70 hips in 35 patients who were diagnosed with early stage osteoarthritis of the hip, and 60 hips from 30 healthy volunteers were analysed. Plain FP radiographs were taken, and vertical-centre-anterior margin (FP-VCA) angles were measured. Acetabular anterior coverage was measured in the natural standing position using a tomosynthesis imaging system in the sagittal plane...
January 23, 2017: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/28163986/neurobiologically-based-treatments-in-rett-syndrome-opportunities-and-challenges
#17
REVIEW
Walter E Kaufmann, Jennifer L Stallworth, David B Everman, Steven A Skinner
Introduction: Rett syndrome (RTT) is an X-linked neurodevelopmental disorder that primarily affects females, typically resulting in a period of developmental regression in early childhood followed by stabilization and severe chronic cognitive, behavioral, and physical disability. No known treatment exists beyond symptomatic management, and while insights into the genetic cause, pathophysiology, neurobiology, and natural history of RTT have been gained, many challenges remain. Areas covered: Based on a comprehensive survey of the primary literature on RTT, this article describes and comments upon the general and unique features of the disorder, genetic and neurobiological bases of drug development, and the history of clinical trials in RTT, with an emphasis on drug trial design, outcome measures, and implementation...
October 2, 2016: Expert Opinion on Orphan Drugs
https://www.readbyqxmd.com/read/28162103/a-study-of-associations-between-early-dha-status-and-fatty-acid-desaturase-fads-snp-and-developmental-outcomes-in-children-of-obese-mothers
#18
Karina R Andersen, Laurine B S Harsløf, Theresia M Schnurr, Torben Hansen, Lars I Hellgren, Kim F Michaelsen, Lotte Lauritzen
DHA from diet or endogenous synthesis has been proposed to affect infant development, however, results are inconclusive. In this study, we aim to verify previously observed fatty acid desaturase gene cluster (FADS) SNP-specific associations with erythrocyte DHA status in 9-month-old children and sex-specific association with developmental outcomes. The study was performed in 166 children (55 % boys) of obese mothers. Erythrocyte fatty acid composition was analysed in blood-samples obtained at 9 months of age, and developmental outcomes assessed by the Ages and Stages Questionnaire at 3 years...
February 6, 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28158246/suitable-indicators-using-stem-diameter-variation-derived-indices-to-monitor-the-water-status-of-greenhouse-tomato-plants
#19
Zhaojiang Meng, Aiwang Duan, Deli Chen, Kithsiri Bandara Dassanayake, Xiaosen Wang, Zugui Liu, Hao Liu, Shengguo Gao
It is very important to seek a simple nondestructive method to continuously measure plant water status for irrigation scheduling. Changes in stem diameter in response to plant water status and soil water content (SWC) were experimentally investigated during the growing seasons of 2011/2012 and 2012/2013 in pot-cultivated tomato (Lycopersicon esculentum L.) plants in a plastic greenhouse. This study was conducted to determine suitable SDV (stem diameter variation)-derived indices as indicators of tomato plant water status for irrigation scheduling...
2017: PloS One
https://www.readbyqxmd.com/read/28157551/the-predictive-value-of-childhood-subthreshold-manic-symptoms-for-adolescent-and-adult-psychiatric-outcomes
#20
Efstathios Papachristou, Albertine J Oldehinkel, Johan Ormel, Dennis Raven, Catharina A Hartman, Sophia Frangou, Abraham Reichenberg
BACKGROUND: Childhood subthreshold manic symptoms may represent a state of developmental vulnerability to Bipolar Disorder (BD) and may also be associated with other adverse psychiatric outcomes. To test this hypothesis we examined the structure and predictive value of childhood subthreshold manic symptoms for common psychiatric disorders presenting by early adulthood. METHODS: Subthreshold manic symptoms at age 11 years and lifetime clinical outcomes by age 19 years were ascertained in the TRacking Adolescents' Individual Lives Survey (TRAILS), a prospective Dutch community cohort...
January 24, 2017: Journal of Affective Disorders
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