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developmental regression

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https://www.readbyqxmd.com/read/28433088/parental-age-and-offspring-psychopathology-in-the-philadelphia-neurodevelopmental-cohort
#1
Alison K Merikangas, Monica E Calkins, Warren B Bilker, Tyler M Moore, Ruben C Gur, Raquel E Gur
OBJECTIVE: Increasing evidence implicates advanced paternal age at offspring birth in neuropsychiatric disorders. Advanced maternal age has also been associated with schizophrenia and other neurodevelopmental disorders, whereas younger maternal age has been linked with behavioral disorders. Few studies have considered the specificity of the associations with respect to comorbidity. In addition, most prior studies have been conducted in clinical samples or registries that may reflect more severe forms of psychopathology...
May 2017: Journal of the American Academy of Child and Adolescent Psychiatry
https://www.readbyqxmd.com/read/28432690/sucking-behaviour-in-infants-born-preterm-and-developmental-outcomes-at-primary-school-age
#2
Mechteld I Wolthuis-Stigter, Saakje P Da Costa, Arend F Bos, Wim P Krijnen, Cees P Van Der Schans, Margreet R Luinge
AIM: To determine the association between sucking in infants born preterm and developmental outcomes at 5 years. METHOD: Thirty-four infants were included (mean gestational age 30wks 4d, mean birthweight 1407g). The Neonatal Oral-Motor Assessment Scale was used longitudinally from 37 to 50 weeks postmenstrual age. At 5 years, we assessed motor skills, intelligence, language, verbal memory, and behavioural problems. Linear regression analyses were performed to test whether aspects of sucking behaviour predicted these developmental outcomes...
April 22, 2017: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/28431988/time-trends-in-births-and-cesarean-deliveries-among-women-with-disabilities
#3
Willi Horner-Johnson, Frances M Biel, Blair G Darney, Aaron B Caughey
BACKGROUND: Although it is likely that childbearing among women with disabilities is increasing, no empirical data have been published on changes over time in the numbers of women with disabilities giving birth. Further, while it is known that women with disabilities are at increased risk of cesarean delivery, temporal trends in cesarean deliveries among women with disabilities have not been examined. OBJECTIVE: To assess time trends in births by any mode and in primary cesarean deliveries among women with physical, sensory, or intellectual/developmental disabilities...
April 6, 2017: Disability and Health Journal
https://www.readbyqxmd.com/read/28429244/fluctuating-asymmetry-of-meristic-traits-an-isofemale-line-analysis-in-an-invasive-drosophilid-zaprionus-indianus
#4
Lilian Madi-Ravazzi, Luis Fernando Segala, Vincent Debat, Jean R David
Metric (e.g., body size) and meristic (e.g., bristle number) traits are of general use in quantitative genetic studies, and the phenotypic variance is subdivided into a genetic and a non-genetic environmental component. The non-genetic variance may have two origins: a common garden effect between individuals and a developmental instability within the same individual. Developmental instability may be studied by considering the fluctuating asymmetry (FA) between the two sides of the body. The isofemale line technique is a convenient method for investigating the architecture of natural populations but has been rarely implemented for investigating FA...
April 20, 2017: Genetica
https://www.readbyqxmd.com/read/28425202/examining-solutions-to-missing-data-in-longitudinal-nursing-research
#5
Mary B Roberts, Mary C Sullivan, Suzy B Winchester
PURPOSE: Longitudinal studies are highly valuable in pediatrics because they provide useful data about developmental patterns of child health and behavior over time. When data are missing, the value of the research is impacted. The study's purpose was to (1) introduce a three-step approach to assess and address missing data and (2) illustrate this approach using categorical and continuous-level variables from a longitudinal study of premature infants. METHODS: A three-step approach with simulations was followed to assess the amount and pattern of missing data and to determine the most appropriate imputation method for the missing data...
April 2017: Journal for Specialists in Pediatric Nursing: JSPN
https://www.readbyqxmd.com/read/28421013/the-blurred-future-of-adolescent-gamblers-impulsivity-time-horizon-and-emotional-distress
#6
Giovanna Nigro, Marina Cosenza, Maria Ciccarelli
The main purpose of this study was to investigate the interplay of functional and dysfunctional impulsivity, delay discounting, time perspective, and emotional negative states on gambling severity in Italian adolescents. A second aim of the study was to analyze the developmental trajectories of gambling involvement, functional and dysfunctional impulsivity, delay discounting, consideration of future consequences, and negative affectivity in a cross-sectional perspective. One thousand and ten Italian adolescents aging between 12 and 19 years were administered the South Oaks Gambling Screen Revised for Adolescents (SOGS-RA), the Functional and Dysfunctional Impulsivity Scale (FDIS), the Monetary Choice Questionnaire (MCQ), the Consideration of Future Consequences Scale (CFC-14), and the Depression, Anxiety and Stress Scales-21 (DASS-21)...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28420388/association-between-maternal-intake-of-n-6-to-n-3-fatty-acid-ratio-during-pregnancy-and-infant-neurodevelopment-at-6-months-of-age-results-of-the-moceh-cohort-study
#7
Hyejin Kim, Hyesook Kim, Eunjung Lee, Yeni Kim, Eun-Hee Ha, Namsoo Chang
BACKGROUND & AIMS: Long-chain polyunsaturated fatty acids (LC-PUFAs) are essential for infant neurodevelopment. The nutritional adequacy of dietary LC-PUFAs depends not only on the LC-PUFAs intake but also on the n-6 to n-3 fatty acid ratio (n-6/n-3 PUFAs). This study aimed to identify the association between the maternal dietary n-6/n-3 PUFAs and motor and cognitive development of infants at 6 months of age. METHODS: We used data from 960 participants in the Mothers and Children's Environmental Health (MOCEH) study, which is a multi-center prospective cohort study...
April 18, 2017: Nutrition Journal
https://www.readbyqxmd.com/read/28417257/additive-effect-of-congenital-heart-disease-and-early-developmental-disorders-on-attention-deficit-hyperactivity-disorder-and-autism-spectrum-disorder-a-nationwide-population-based-longitudinal-study
#8
Pei-Chen Tsao, Yu-Sheng Lee, Mei-Jy Jeng, Ju-Wei Hsu, Kai-Lin Huang, Shih-Jen Tsai, Mu-Hong Chen, Wen-Jue Soong, Yu Ru Kou
In this retrospective nationwide population-based case-control study, we investigated the impact of congenital heart disease (CHD) on the development of attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD), which remains unclear. Children aged <18 years that were diagnosed with CHD (n = 3552) between January 1, 1997 and December 31, 2009 were identified from the National Health Insurance Research Database in Taiwan. Non-CHD controls (n = 14,208) matched for age and sex (1:4) were selected from the same dataset...
April 17, 2017: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/28417256/to-which-extent-social-withdrawal-at-the-age-of-1%C3%A2-year-is-associated-with-iq-at-5-6%C3%A2-years-old-results-of-the-eden-mother-child-cohort
#9
Antoine Guedeney, Sarah Doukhan, Anne Forhan, Barbara Heude, Hugo Peyre
The present study aims to determine to which extent social withdrawal at 1 year is associated with the child's IQ at the end of the preschool period. Children (N = 1045) from the EDEN mother-child cohort were assessed for social withdrawal behaviours at 1 year by trained midwives using the Alarm Distress BaBy (ADBB) scale. Midwives also examined infants' language and motor development at 1 year. At the age 5-6 years, IQ scores were based on the WPPSI-III. Linear regression models were used to determine the association between IQ and ADBB, adjusted for a broad range of pre- and postnatal environmental factors and for language and motor skills scores at 1 year...
April 17, 2017: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/28412301/environmental-risks-outweigh-dopaminergic-genetic-risks-for-alcohol-use-and-abuse-from-adolescence-through-early-adulthood
#10
Rebekah Levine Coley, Jacqueline Sims, Jennifer Carrano
BACKGROUND: Alcohol use is a primary public health concern, particularly among adolescents and young adults. Based on the rapidly growing field of gene-environment models, this study assessed the combined role of environmental and dopamine-related genetic correlates of early alcohol use and abuse. METHODS: Multilevel growth models assessed trajectories of alcohol use and intoxication and ordered logistic regressions assessed alcohol use disorder among a sample of 12,437 youth from the nationally representative Add Health study who were followed from mid-adolescence through early adulthood...
March 31, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28411844/research-techniques-made-simple-mass-cytometry%C3%A2-analysis-tools-for-decrypting-the%C3%A2-complexity%C3%A2-of-biological-systems
#11
Tiago R Matos, Hongye Liu, Jerome Ritz
Mass cytometry by time-of-flight experiments allow analysis of over 40 functional and phenotypic cellular markers simultaneously at the single-cell level. The data dimensionality escalation accentuates limitations, inherent to manual analysis, as being subjective, labor-intensive, slow, and often incapable of showing the detailed features of each unique cell within populations. The subsequent challenge of examining, visualizing, and presenting mass cytometry data has motivated continuous development of dimensionality reduction methods...
May 2017: Journal of Investigative Dermatology
https://www.readbyqxmd.com/read/28411449/prenatal-concentrations-of-perfluoroalkyl-substances-and-early-communication-development-in-british-girls
#12
Zuha Jeddy, Terryl J Hartman, Ethel V Taylor, Cayla Poteete, Katarzyna Kordas
Perfluoroalkyl substances (PFAS), found in many household products and classed as endocrine disrupting chemicals, can be transferred through the placenta and are associated with multiple developmental deficits in offspring. Using data from the Avon Longitudinal Study of Parents and Children (ALSPAC), we investigated the association between intrauterine exposure to PFAS and early communication development in 432 mother-daughter dyads at 15 and 38months of age. Concentrations of perfluorooctane sulfonate (PFOS), perfluorooctanoate (PFOA), perfluorohexane sulfonate (PFHxS), and perfluorononanoate (PFNA) were measured in maternal serum collected during pregnancy...
April 12, 2017: Early Human Development
https://www.readbyqxmd.com/read/28411008/cone-beam-computed-tomography-incidental-findings-of-the-cervical-spine-and-clivus-retrospective-analysis-and-review-of-the-literature
#13
Noura A Alsufyani
OBJECTIVE: The aim of this study was to analyze and describe incidental findings in the cervical spine (C-spine) and the clivus encountered in cone beam computed tomography (CBCT) imaging. The wide range of possible anatomic variants and pathoses is discussed in the context of the medical and dental literature to clarify their radiographic appearance and clinical implications as a guide for the oral and maxillofacial radiologist. STUDY DESIGN: A retrospective analysis of radiographic reports was conducted based on CBCT images from 2 oral and maxillofacial imaging centers...
March 19, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28410256/parent-reported-severity-and-health-educational-services-use-among-us-children-with-autism-results-from-a-national-survey
#14
Katharine E Zuckerman, Nora D B Friedman, Alison E Chavez, Amy M Shui, Karen A Kuhlthau
OBJECTIVE: Little national data exist regarding service use patterns for children with autism spectrum disorder (ASD) of varying severity. This study aimed to assess the relationship between parent-reported severity and use of educational and health care services. METHODS: Data from the 2011 Survey of Pathways to Diagnosis and Services were used to examine a nationally representative sample of 1420 US children aged 6 to 17 years with ASD, with or without developmental delay and intellectual disability...
April 12, 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/28404230/birth-outcomes-among-us-women-with-intellectual-and-developmental-disabilities
#15
Ilhom Akobirshoev, Susan L Parish, Monika Mitra, Eliana Rosenthal
BACKGROUND: Women with intellectual and developmental disabilities (IDD) are bearing children at increasing rates. However, there is very little research about pregnancy experiences and birth outcomes among women with IDD. No studies to date have examined birth outcomes with a US population-based sample. OBJECTIVE: The main objective was to estimate the national occurrence of deliveries in women with IDD and to compare their birth outcomes to women without IDD. METHODS: We examined the 2007-2011 Nationwide Inpatient Sample of the Healthcare Cost and Utilization Project to compare birth outcomes in women with and without IDD...
April 6, 2017: Disability and Health Journal
https://www.readbyqxmd.com/read/28401948/development-and-validation-of-a-method-for-precise-dating-of-female-puberty-in-laboratory-rodents-the-puberty-ovarian-maturation-score-pub-score
#16
Francisco Gaytan, Concepción Morales, Silvia Leon, Violeta Heras, Alexia Barroso, Maria S Avendaño, Maria J Vazquez, Juan M Castellano, Juan Roa, Manuel Tena-Sempere
Puberty is a key developmental event whose primary regulatory mechanisms remain poorly understood. Precise dating of puberty is crucial for experimental (preclinical) studies on its complex neuroendocrine controlling networks. In female laboratory rodents, external signs of puberty, such as vaginal opening (VO) and epithelial cell cornification (i.e., first vaginal estrus, FE), are indirectly related to the maturational state of the ovary and first ovulation, which is the unequivocal marker of puberty. Whereas in rats, VO and FE are almost simultaneous with the first ovulation, these events are not so closely associated in mice...
April 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28398695/social-disadvantage-and-developmental-diagnosis-in-pre-schoolers
#17
Norma Kayrouz, Susan L Milne, Jenny L McDonald
AIM: To explore the association between social disadvantage and developmental diagnoses in pre-school children. METHODS: Between 2012 and 2015, 845 pre-school children were assessed by the Child Assessment Team at Campbelltown Hospital. A social worker interviewed 469 families and these children were eligible for inclusion in the study. Autism spectrum disorder (ASD) was confirmed in 290 children. Of those without ASD, 72 did not have global developmental delay (GDD) and were excluded from the study...
April 11, 2017: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/28398477/elective-embryo-transfers-on-day-6-reduce-implantation-compared-with-transfers-on-day-5
#18
V Poulsen, H J Ingerslev, K Kirkegaard
STUDY QUESTION: Is there a difference in pregnancy rates between embryos transferred electively on Day 5 and Day 6, respectively? SUMMARY ANSWER: The chance of pregnancy is significantly reduced (odds ratio (OR): 0.34; 95% CI 0.22-0.52) if transfer is performed on Day 6 compared with Day 5. WHAT IS KNOWN ALREADY: Several studies report that Day 5 transfers have higher implantation rates (IRs) when compared with Day 6 transfers. These studies were based on non-elective Day 6 transfers, where transfers on Day 6 were performed with developmentally delayed embryos...
April 7, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28395578/changing-relations-among-cognitive-abilities-across-development-implications-for-measurement-and-research
#19
Jala Rizeq, David B Flora, Maggie E Toplak
OBJECTIVE: The constructs of intelligence and executive function (EF) are commonly used in neuropsychological, cognitive, and developmental research, and in the context of clinical assessment. Yet, we have a limited understanding of the changing age-related associations among these cognitive constructs and the implications for measurement and research. The objectives of this study were to compare hypothetical models using intellectual abilities (non-age corrected scores of intelligence or IQ) and experimental measures of EF and to better understand the role of age in determining the associations between these cognitive abilities at two different periods of development...
April 11, 2017: Clinical Neuropsychologist
https://www.readbyqxmd.com/read/28393350/randomised-trial-of-a-parent-mediated-intervention-for-infants-at-high-risk-for-autism-longitudinal-outcomes-to-age-3%C3%A2-years
#20
J Green, A Pickles, G Pasco, R Bedford, M W Wan, M Elsabbagh, V Slonims, T Gliga, E J H Jones, C H M Cheung, T Charman, M H Johnson
BACKGROUND: There has been increasing interest in the potential for pre-emptive interventions in the prodrome of autism, but little investigation as to their effect. METHODS: A two-site, two-arm assessor-blinded randomised controlled trial (RCT) of a 12-session parent-mediated social communication intervention delivered between 9 and 14 months of age (Intervention in the British Autism Study of Infant Siblings-Video Interaction for Promoting Positive Parenting), against no intervention...
April 10, 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
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