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https://www.readbyqxmd.com/read/29667846/effect-of-gender-on-breast-and-thigh-turkey-meat-quality
#1
F Gálvez, R Domínguez, M Pateiro, J Carballo, I Tomasevic, J M Lorenzo
1. The influence of gender on chemical composition, physicochemical parameters, fatty acid profile, amino acid and mineral composition of turkey breast and thigh meat was studied in order to assess nutrient requirements. 2. Chemical composition showed that only intramuscular fat in breast meat was significantly affected by gender (P<0.05). The results showed a higher percentage of intramuscular fat in male samples, almost double the amount found in females (0.73% vs. 0.38%). 3.For meat colour parameters, only a* showed different results between sexes, with male samples (breast: P<0...
April 18, 2018: British Poultry Science
https://www.readbyqxmd.com/read/29664968/water-system-is-a-controlling-variable-modulating-bacterial-diversity-of-gastrointestinal-tract-and-performance-in-rainbow-trout
#2
Omolola C Betiku, Carl J Yeoman, T Gibson Gaylord, Benjamin Americus, Sarah Olivo, Glenn C Duff, Wendy M Sealey
A two-phase feeding study evaluating performance of rainbow trout and comparing luminal and mucosal gastrointestinal tract (GIT) bacterial community compositions when fed two alternative protein diets in two rearing systems was conducted. Alternative protein diets (animal protein and plant protein diets) balanced with crystalline amino acids: lysine, methionine and threonine or unbalanced, were fed to rainbow trout in two separate water systems (recirculating (RR) and flow-through (FF)) for a period of 16 weeks...
2018: PloS One
https://www.readbyqxmd.com/read/29664912/metatranscriptome-analysis-of-the-microbial-fermentation-of-dietary-milk-proteins-in-the-murine-gut
#3
Floor Hugenholtz, Mark Davids, Jessica Schwarz, Michael Müller, Daniel Tomé, Peter Schaap, Guido J E J Hooiveld, Hauke Smidt, Michiel Kleerebezem
Undigestible food ingredients are converted by the microbiota into a large range of metabolites, predominated by short chain fatty acids (SCFA). These microbial metabolites are subsequently available for absorption by the host mucosa and can serve as an energy source. Amino acids fermentation by the microbiota expands the spectrum of fermentation end-products beyond acetate, propionate and butyrate, to include in particular branched-SCFA. Here the long-term effects of high protein-diets on microbial community composition and functionality in mice were analyzed...
2018: PloS One
https://www.readbyqxmd.com/read/29663011/plasma-branched-chain-aromatic-amino-acids-enriched-mediterranean-diet-and-risk-of-type-2-diabetes-case-cohort-study-within-the-predimed-trial
#4
Miguel Ruiz-Canela, Marta Guasch-Ferré, Estefanía Toledo, Clary B Clish, Cristina Razquin, Liming Liang, Dong D Wang, Dolores Corella, Ramón Estruch, Álvaro Hernáez, Edward Yu, Enrique Gómez-Gracia, Yan Zheng, Fernando Arós, Dora Romaguera, Courtney Dennis, Emilio Ros, José Lapetra, Lluis Serra-Majem, Christopher Papandreou, Olga Portoles, Montserrat Fitó, Jordi Salas-Salvadó, Frank B Hu, Miguel A Martínez-González
AIMS/HYPOTHESIS: Branched-chain amino acids (BCAAs) and aromatic amino acids (AAAs) are associated with type 2 diabetes. However, repeated measurements of BCAA/AAA and their interactions with dietary interventions have not been evaluated. We investigated the associations between baseline and changes at 1 year in BCAA/AAA with type 2 diabetes in the context of a Mediterranean diet (MedDiet) trial. METHODS: We included 251 participants with incident type 2 diabetes and a random sample of 694 participants (641 participants without type 2 diabetes and 53 overlapping cases) in a case-cohort study nested within the PREvención con DIeta MEDiterránea (PREDIMED) trial...
April 16, 2018: Diabetologia
https://www.readbyqxmd.com/read/29656381/cowpea-an-overview-on-its-nutritional-facts-and-health-benefits
#5
REVIEW
Chathuni Jayathilake, Rizliya Visvanathan, Afka Deen, Ruksheela Bangamuwage, Barana C Jayawardana, Srinivas Nammi, Ruvini Liyanage
Cowpea (Vigna unguiculata) is a legume consumed as a high-quality plant protein source in many parts of the world. High protein and carbohydrate contents with relatively low fat content and complementary amino acid pattern to that of cereal grains make cowpea an important nutritional food in the human diet. Cowpea has gained more attention recently from consumers and researchers worldwide due to its exerted health beneficial properties including anti-diabetic, anti-cancer, anti-hyperlipidemic, anti-inflammatory and anti-hypertensive properties...
April 15, 2018: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/29656123/selenium-supplementation-prevents-metabolic-and-transcriptomic-responses-to-cadmium-in-mouse-lung
#6
Xin Hu, Joshua D Chandler, Jolyn Fernandes, Michael L Orr, Li Hao, Karan Uppal, David C Neujahr, Dean P Jones, Young-Mi Go
BACKGROUND: The protective effect of selenium (Se) on cadmium (Cd) toxicity is well documented, but underlying mechanisms are unclear. METHODS: Male mice fed standard diet were given Cd (CdCl2 , 18 μmol/L) in drinking water with or without Se (Na2 SeO4, 20 μmol/L) for 16 weeks. Lungs were analyzed for Cd concentration, transcriptomics and metabolomics. Data were analyzed with biostatistics, bioinformatics, pathway enrichment analysis, and combined transcriptome-metabolome-wide association study...
April 12, 2018: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/29651010/dietary-supplementation-with-flaxseed-meal-and-oat-hulls-modulates-intestinal-histomorphometric-characteristics-digesta-and-mucosa-associated-microbiota-in-pigs
#7
S P Ndou, H M Tun, E Kiarie, M C Walsh, E Khafipour, C M Nyachoti
The establishment of a healthy gastrointestinal milieu may not only offer an opportunity to reduce swine production costs but could also open the way for a lifetime of human health improvement. This study investigates the effects of feeding soluble fibre from flaxseed meal-containing diet (FM) and insoluble fibre from oat hulls-containing diet (OH) on histomorphological characteristics, digesta- and mucosa-associated microbiota and their associations with metabolites in pig intestines. In comparison with the control (CON) and OH diets, the consumption of FM increased (P < 0...
April 12, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29628462/-long-term-dietary-nitrite-and-nitrate-deficiency-causes-metabolic-syndrome-endothelial-dysfunction-and-cardiovascular-death-in-mice
#8
Mika Kina-Tanada, Mayuko Sakanashi, Akira Arasaki, Masato Tsutsui
Nitric oxide (NO) is synthesized not only from L-arginine by NO synthases (NOSs), but also from its inert metabolites, nitrite and nitrate. Green leafy vegetables are abundant in nitrate, however whether or not a deficiency in dietary nitrite/nitrate spontaneously causes disease remains to be clarified. In this study, we tested our hypothesis that long-term dietary nitrite/nitrate deficiency induces metabolic syndrome (MetS) in mice. To this end, we prepared a low nitrite/nitrate diet (LND) consisting of an amino acid-based low nitrite/nitrate chow in which the contents of L-arginine, fat, carbohydrates, protein, and energy were identical with a regular chow, and potable ultrapure water...
2018: Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica
https://www.readbyqxmd.com/read/29625864/dietary-intakes-of-branched-chained-amino-acid-and-risk-for-type-2-diabetes-in-adults-the-harbin-cohort-study-on-diet-nutrition-and-chronic-non-communicable-diseases-study
#9
Akinkunmi Paul Okekunle, Xiaoyan Wu, Wei Duan, Rennan Feng, Ying Li, Changhao Sun
OBJECTIVES: To assess the association between branched-chain amino acid (BCAA) intakes and risk for type 2 diabetes. METHODS: Dietary intakes were assessed in 1,804 people with type 2 diabetes and 7,020 controls with information on nutrient intakes, including BCAAs derived from Chinese food composition tables. Principal component analysis was used to identify dietary patterns (DPs) and multivariable-adjusted odds ratios (ORs) of type 2 diabetes, and 95% confidence intervals (CIs) by quartiles of BCAAs were estimated using logistic regression with 2-sided p<0...
December 12, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/29621327/effects-of-feed-allowance-and-indispensable-amino-acid-reduction-on-feed-intake-growth-performance-and-carcass-characteristics-of-growing-pigs
#10
Stefano Schiavon, Mirco Dalla Bona, Giuseppe Carcò, Luca Carraro, Lutz Bunger, Luigi Gallo
The hypothesis that pigs placed on diets with reduced indispensable amino acid (AA) content attempts to offset the reduction in the nutrient density with increased feed intake was tested. In the experiment, feeds with a high or a low AA content were administrated to pigs fed ad-libitum or restrictively according to a 2 × 2 factorial design. Ninety-six barrows were housed in 8 pens (12 pigs/pen) equipped with automatic feeders. Within pen, and from 47 body weight (BW) onwards, 6 pigs were fed ad libitum. The others pigs were allowed to consume, as a maximum, the feed amounts indicated by the breeding company feeding plane to optimize the feed efficiency...
2018: PloS One
https://www.readbyqxmd.com/read/29620942/food-withdrawal-alters-the-gut-microbiota-and-metabolome-in-mice
#11
Xiaojiao Zheng, Kejun Zhou, Yunjing Zhang, Xiaolong Han, Aihua Zhao, Jiajian Liu, Chun Qu, Kun Ge, Fengjie Huang, Brenda Hernandez, Herbert Yu, Jun Panee, Tianlu Chen, Weiping Jia, Wei Jia
Food withdrawal as a health-enhancing measure has beneficial effects on aging, disease prevention, and treatment. However, the cellular and molecular mechanisms involving gut microbial changes and metabolic consequences resulting from food withdrawal have yet to be elucidated. In this study, we subjected lean and obese mice to a dietary intervention that consisted of a 4-d complete food withdrawal and an 8-d 50% food withdrawal, and we studied changes in cecal microbiome and host serum metabolome. The abundance of potentially pathogenic Proteobacteria was decreased and Akkermansia muciniphila was elevated by food withdrawal in mice fed a high-fat diet (HFD)...
April 5, 2018: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/29619822/drosophila-melanogaster-as-a-versatile-model-organism-in-food-and-nutrition-research
#12
Stefanie Staats, Kai Lüersen, Anika E Wagner, Gerald Rimbach
Drosophila melanogaster has been widely used in the biological sciences as a model organism. Drosophila has a relatively short life span of 60-80 days, which makes it attractive for life span studies. Moreover, approximately 60% of the fruit fly genes are orthologs to mammals. Thus, metabolic and signal transduction pathways are highly conserved. Maintenance and reproduction of Drosophila do not require sophisticated equipment and are rather cheap. Furthermore, there are fewer ethical issues involved in experimental Drosophila research compared with studies in laboratory rodents, such as rats and mice...
April 5, 2018: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29615653/importance-of-serum-amino-acid-profile-for-induction-of-hepatic-steatosis-under-protein-malnutrition
#13
Hiroki Nishi, Daisuke Yamanaka, Hiroyasu Kamei, Yuki Goda, Mikako Kumano, Yuka Toyoshima, Asako Takenaka, Masato Masuda, Yasushi Nakabayashi, Ryuji Shioya, Naoyuki Kataoka, Fumihiko Hakuno, Shin-Ichiro Takahashi
We previously reported that a low-protein diet caused animals to develop fatty liver containing a high level of triglycerides (TG), similar to the human nutritional disorder "kwashiorkor". To investigate the underlying mechanisms, we cultured hepatocytes in amino acid-sufficient or deficient medium. Surprisingly, the intracellular TG level was increased by amino acid deficiency without addition of any lipids or hormones, accompanied by enhanced lipid synthesis, indicating that hepatocytes themselves monitored the extracellular amino acid concentrations to induce lipid accumulation in a cell-autonomous manner...
April 3, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29614018/in-vitro-influence-of-extracts-from-snail-helix-aspersa-m%C3%A3-ller-on-the-colon-cancer-cell-line-caco-2
#14
Magdalena Matusiewicz, Iwona Kosieradzka, Tomasz Niemiec, Marta Grodzik, Hanna Antushevich, Barbara Strojny, Małgorzata Gołębiewska
Colorectal cancer is the third most widely diagnosed cancer. Extracts from snails may modulate growth and development of colorectal cancer cells. The objective of this study was to determine the chemical composition of tissues derived from Helix aspersa Müller and red-ox properties of tissue extracts. Then, the influence of extracts and their fractions of different molecular weights on viability of Caco-2 cells was examined. Tissue lyophilisates contained antioxidants that could be important in the prevention of colorectal cancer...
April 3, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29609181/improved-uterine-immune-mediators-in-holstein-cows-supplemented-with-rumen-protected-methionine-and-discovery-of-neutrophil-extracellular-traps-net
#15
S L Stella, D A Velasco-Acosta, C Skenandore, Z Zhou, A Steelman, D Luchini, F C Cardoso
During the transition from prepartum to early lactation, dairy cows often experience negative energy balance (NEB) that may result in reproductive stress and decreased fertility. The objective of this study was to observe the effects of rumen-protected methionine (RPM) on plasma amino acid concentrations, uterine cytology, immunohistochemistry (IHC) of glutathione peroxidase 1 (GPX) and superoxide dismutase 1 (SOD), and to confirm neutrophil extracellular trap (NET) formation. Multiparous Holstein cows (n = 20) were randomly assigned to two treatments starting at 21 d before calving until 73 days in milk (DIM)...
March 26, 2018: Theriogenology
https://www.readbyqxmd.com/read/29606470/reducing-the-allergenic-capacity-of-%C3%AE-lactoglobulin-by-covalent-conjugation-with-dietary-polyphenols
#16
Xuli Wu, Yuqin Lu, Haoxie Xu, Dongxu Lin, Zhendan He, Haiqiang Wu, Lizhong Liu, Zimei Wang
To help produce hypoallergenic food, this study investigated reducing the allergenicity and improving the functional properties of bovine β-lactoglobulin (βLG) by covalent conjugation with (-)-epigallo-catechin 3-gallate (EGCG) and chlorogenic acid (CA). The covalent bond between the polyphenols and the amino acid side-chains in βLG was confirmed by MALDI-TOF-MS and SDS-PAGE. Structural analysis by fluorescence spectroscopy, circular dichroism (CD) and Fourier transform infrared (FTIR) indicated that the covalent conjugate of EGCG and CA led to the changed protein structure of βLG...
August 1, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29596961/protein-restriction-and-cancer
#17
REVIEW
Jie Yin, Wenkai Ren, Xingguo Huang, Tiejun Li, Yulong Yin
Protein restriction without malnutrition is currently an effective nutritional intervention known to prevent diseases and promote health span from yeast to human. Recently, low protein diets are reported to be associated with lowered cancer incidence and mortality risk of cancers in human. In murine models, protein restriction inhibits tumor growth via mTOR signaling pathway. IGF-1, amino acid metabolic programing, FGF21, and autophagy may also serve as potential mechanisms of protein restriction mediated cancer prevention...
March 26, 2018: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/29590619/serine-availability-influences-mitochondrial-dynamics-and-function-through-lipid-metabolism
#18
Xia Gao, Katie Lee, Michael A Reid, Sydney M Sanderson, Chuping Qiu, Siqi Li, Juan Liu, Jason W Locasale
Cell proliferation can be dependent on the non-essential amino acid serine, and dietary restriction of serine inhibits tumor growth, but the underlying mechanisms remain incompletely understood. Using a metabolomics approach, we found that serine deprivation most predominantly impacts cellular acylcarnitine levels, a signature of altered mitochondrial function. Fuel utilization from fatty acid, glucose, and glutamine is affected by serine deprivation, as are mitochondrial morphological dynamics leading to increased fragmentation...
March 27, 2018: Cell Reports
https://www.readbyqxmd.com/read/29587458/towards-an-integrative-understanding-of-trna-aminoacylation-diet-host-gut-microbiome-interactions-in-neurodegeneration
#19
Elena L Paley, George Perry
Transgenic mice used for Alzheimer's disease (AD) preclinical experiments do not recapitulate the human disease. In our models, the dietary tryptophan metabolite tryptamine produced by human gut microbiome induces tryptophanyl-tRNA synthetase (TrpRS) deficiency with consequent neurodegeneration in cells and mice. Dietary supplements, antibiotics and certain drugs increase tryptamine content in vivo. TrpRS catalyzes tryptophan attachment to tRNAtrp at initial step of protein biosynthesis. Tryptamine that easily crosses the blood-brain barrier induces vasculopathies, neurodegeneration and cell death via TrpRS competitive inhibition...
March 26, 2018: Nutrients
https://www.readbyqxmd.com/read/29581999/astrocyte-dysfunction-following-molybdenum-associated-purine-loading-could-initiate-parkinson-s-disease-with-dementia
#20
REVIEW
Christopher A Bourke
Sporadic or idiopathic Parkinson's disease is a movement disorder with a worldwide distribution, a long pre-clinical latent period and a frequent association with dementia. The combination of molybdenum deficiency and purine ingestion could explain the movement disorder, the distribution, the latent period and the dementia association. Recent studies in sheep have shown that molybdenum deficiency enables some dietary purines to accumulate in the central nervous system. This causes astrocyte dysfunction, altered neuromodulation and eventually irreversible central nervous system disease...
2018: NPJ Parkinson's Disease
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