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Kevin Makati

Drew Ertel, Kavita Phatak, Kevin Makati, Marian Holland, Sara Baig, Michael H Kim, Mark Link, Rod Passman
BACKGROUND: There are no upper age restrictions for implantable defibrillators (ICDs) but their benefit may be limited in patients > or = 80 years with strong competing risks of early mortality. Risk factors for early (1-year) mortality in ICD recipients > or = 80 years of age have not been established. METHODS: Two-center retrospective cohort study to assess predictors of one-year mortality in ICD recipients > or = 80 years of age. RESULTS: Of 2,967 ICDs implanted in the two centers from 1990-2006, 225 (7...
August 2010: Pacing and Clinical Electrophysiology: PACE
Isabelle Nault, Frederic Sacher, Sebastien Knecht, Matthew Wright, Nicolas Lellouche, Seiichiro Matsuo, Kevin J Makati, Meleze Hocini, Pierre Jaïs, Michel Haïssaguerre
We describe a case of a young man referred with a broad complex tachycardia for evaluation and ablation. Electrophysiological study was performed and revealed a left lateral accessory pathway with antegrade decremental conduction causing antidromic reciprocating re-entrant tachycardia. Ablation was successfully performed. Left lateral accessory pathways with decremental conduction are rarely encountered.
November 2008: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
Sébastien Knecht, Mélèze Hocini, Matthew Wright, Nicolas Lellouche, Mark D O'Neill, Seiichiro Matsuo, Isabelle Nault, Vijay S Chauhan, Kevin J Makati, Michela Bevilacqua, Kang-Teng Lim, Frederic Sacher, Antoine Deplagne, Nicolas Derval, Pierre Bordachar, Pierre Jaïs, Jacques Clémenty, Michel Haïssaguerre
AIMS: This study evaluates the clinical outcome and incidence of left atrial (LA) macro re-entrant atrial tachycardia (AT) in patients in whom persistent atrial fibrillation (AF) terminated during catheter ablation without the need of roof and mitral lines. METHODS AND RESULTS: Persistent AF was terminated by ablation in 154 of 180 consecutive patients. AF history was 60 months including 11 months of continuous AF. Patients were divided into two groups: those who had not required both LA linear lesions to terminate AF (group A, 85 patients), and those who had (group B, 69 patients)...
October 2008: European Heart Journal
Kevin J Makati, Alawi A Alsheikh-Ali, Ann C Garlitski, Mark S Link, Munther Homoud, Jonathan Weinstock, N A Mark Estes Iii
The mechanisms to explain atrial fibrillation (AF) have been widely debated. Although contemporary experimental techniques have provided more insight, hypotheses regarding AF propagation conceived in the early half of the century remain minimally altered and relevant today. Modern mapping technologies have implicated multiwavelet reentry as the electrophysiologic basis to explain AF propagation within the atrial myocardium; however, reentry has also been observed within pulmonary veins and may behave as a focal trigger...
October 2008: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
Kevin J Makati, Airley E Fish, Hannah H England, Hocine Tighiouart, N A Mark Estes, Mark S Link
BACKGROUND: The Centers for Medicare and Medicaid Services (CMS) recently expanded coverage for implantable cardioverter-defibrillators (ICDs) in patients with left ventricular ejection fraction < or =35% and nonischemic dilated cardiomyopathy for > or =9 months. To investigate the ramifications of these criteria, the ICD registry from Tufts-New England Medical Center was analyzed for arrhythmic events and death in patients with newly diagnosed (<9 months) vs late-diagnosed (> or =9 months) nonischemic dilated cardiomyopathy...
April 2006: Heart Rhythm: the Official Journal of the Heart Rhythm Society
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