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Ivf and intralipid

J H Check, D L Check
PURPOSE: To evaluate the efficacy of intralipid intravenous infusion in achieving a live pregnancy following IVF--embryo transfer in women of advanced reproductive age (40-42 years). MATERIALS AND METHODS: A matched control was performed. Women aged 40-42 with a previous history of miscarriage or who failed to conceive despite previous embryo transfer who entered an IVF program were offered intravenous intralipid therapy (four ml of 20% liposyn II in 100 ml normal saline over one hour) during the mid-follicular phase...
2016: Clinical and Experimental Obstetrics & Gynecology
Joseph D Presley, Peter A Chyka
OBJECTIVE: To identify and summarize published cases in which intravenous lipid emulsion was used to treat pediatric patients with acute drug toxicities. DATA SOURCES: PubMed, SCOPUS, and EMBASE were searched up to December 2012 for relevant publications using the terms fat emulsion, lipid emulsion, Intralipid, Liposyn, Medialipide, Medialipid, lipid rescue, ILE, IVLE, IFE, IVFE, or lipid and intoxication, overdose, poisoning, toxicity, resuscitation, antidote, and rescue that were limited to reports in humans aged 18 years or younger...
May 2013: Annals of Pharmacotherapy
Roumen G Roussev, Boris V Dons'koi, Christopher Stamatkin, Sivakumar Ramu, Viktor P Chernyshov, Carolyn B Coulam, Eytan R Barnea
Embryo-secreted preimplantation factor (PIF) is necessary for, and its concentration correlates with, embryo development in humans by promoting implantation and trophoblast invasion. Synthetic PIF (sPIF) modulates systemic immunity and is effective in autoimmune disease models. sPIF binds monocytes and activated T and B cells, leading to immune tolerance without suppression. This study examined the effect of sPIF on natural killer (NK) cell cytotoxicity in 107 consecutive nonselected, nonpregnant patients with recurrent pregnancy loss (RPL) and 26 infertile IVF patients (controls)...
January 2013: Reproductive Biomedicine Online
Jay M Mirtallo, Joseph F Dasta, Kurt C Kleinschmidt, Joseph Varon
OBJECTIVE: To review the current state of the science regarding intravenous fat emulsions (IVFEs), with an emphasis on their safety profile. DATA SOURCES: Articles were identified via a search of the MEDLINE database, including publications from 1979 to December 2009, using a search string that included the terms parenteral nutrition, lipid emulsion, fat emulsion, IVFE, safety, adverse effect, neonate intralipid, and terms describing a range of specific adverse events (AEs) such as pancreatitis...
April 2010: Annals of Pharmacotherapy
O Goulet, R Girot, M Maier-Redelsperger, D Bougle, J L Virelizier, C Ricour
Abnormalities in hematologic parameters, associated with prolonged utilization of intravenous fat emulsion (IVFE), were observed in seven children on long-term cyclic total parenteral nutrition (TPN). All patients were receiving IVFE (Intralipid 20%) 1 to 2 g/kg/24 hr as part of TPN, during 3 to 18 months. Recurrent thrombocytopenia occurred in all seven patients. Platelet lifespan, as measured with 111 Indium was reduced. Sea-blue histiocytes containing granulations and hemophagocytosis were seen on bone marrow smears...
May 1986: JPEN. Journal of Parenteral and Enteral Nutrition
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