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https://www.readbyqxmd.com/read/28230198/longitudinal-association-of-hypertension-and-diabetes-mellitus-with-cognitive-functioning-in-a-general-70-year-old-population-the-sonic-study
#1
Hirochika Ryuno, Kei Kamide, Yasuyuki Gondo, Mai Kabayama, Ryosuke Oguro, Chikako Nakama, Serina Yokoyama, Motonori Nagasawa, Satomi Maeda-Hirao, Yuki Imaizumi, Miyuki Takeya, Hiroko Yamamoto, Masao Takeda, Yoichi Takami, Norihisa Itoh, Yasushi Takeya, Koichi Yamamoto, Ken Sugimoto, Takeshi Nakagawa, Saori Yasumoto, Kazunori Ikebe, Hiroki Inagaki, Yukie Masui, Michiyo Takayama, Yasumichi Arai, Tatsuro Ishizaki, Ryutaro Takahashi, Hiromi Rakugi
Both hypertension and diabetes in middle-aged individuals have been suggested to be predictive indicators of cognitive decline. However, the association of hypertension, diabetes and their combination with cognitive functioning is still controversial in older people. The purpose of this study was to investigate the association between cognitive decline and hypertension, diabetes, and their combination in 70-year-old people based on a 3-year longitudinal analysis. Four hundred and fifty-four people aged 70 (±1) years who participated in the Japanese longitudinal cohort study of Septuagenarians, Octogenarians and Nonagenarians Investigation with Centenarians (SONIC) were recruited randomly from a general population and were monitored for 3 years...
February 23, 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28210062/cognitive-function-in-middle-aged-and-older-adults-participating-in-synchronized-swimming-exercise
#2
Etsuko Maeshima, Yuka Okumura, Juri Tatsumi, Sayaka Tomokane, Akiko Ikeshima
[Purpose] The purpose of the present study was to examine cognitive function in middle-aged and older adults regularly engaging in synchronized swimming-exercise. [Subjects and Methods] Twenty-three female synchronized swimmers ranging in age from 49 to 85 years were recruited for the present study. The duration of synchronized swimming experience ranged from 1 to 39 years. The control group consisted of 36 age- and gender-matched community-dwelling middle-aged and older adults (age range: 49 to 77 years)...
January 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28208082/cognitive-impairment-in-the-first-year-after-breast-cancer-diagnosis-a-prospective-cohort-study
#3
Mariana Ramalho, Filipa Fontes, Luís Ruano, Susana Pereira, Nuno Lunet
OBJECTIVES: The objective of this study was to assess the relation between cancer treatments and incident cognitive impairment in breast cancer patients, taking into account the levels of anxiety before treatment. MATERIALS AND METHODS: We conducted a prospective cohort study with 418 newly diagnosed breast cancer patients with no cognitive impairment, defined as values at least 1.5 standard deviations below age- and education-adjusted cut-offs in the Montreal Cognitive Assessment (MoCA), at baseline...
February 13, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28205215/multicenter-validation-of-an-mmse-moca-conversion-table
#4
David Bergeron, Kelsey Flynn, Louis Verret, Stéphane Poulin, Rémi W Bouchard, Christian Bocti, Tamàs Fülöp, Guy Lacombe, Serge Gauthier, Ziad Nasreddine, Robert Jr Laforce
BACKGROUND: Accumulating evidence points to the superiority of the MoCA over the MMSE as a cognitive screening tool. To facilitate the transition from the MMSE to the MoCA in clinical and research settings, authors have developed MMSE-MoCA conversion tables. However, it is unknown whether a conversion table generated from Alzheimer's disease (AD) patients would apply to patients with other dementia subtypes like vascular dementia or frontotemporal dementia. Furthermore, the reliability and accuracy of MMSE-MoCA conversion tables has not been properly evaluated...
February 15, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28199994/association-between-montreal-cognitive-assessment-sub-item-scores-and-corresponding-cognitive-test-performance-in-patients-with-frontotemporal-dementia-and-related-disorders
#5
Kristy K L Coleman, Brenda L Coleman, Julia D MacKinley, Stephen H Pasternak, Elizabeth C Finger
The Montreal Cognitive Assessment (MoCA), a brief screening test developed to detect patients with mild cognitive impairment, is used in clinical settings across North America [Nasreddine et al.: J Am Geriatr Soc 2005;53:695-699]. The MoCA has been demonstrated to be sensitive to cognitive deficits in frontotemporal dementias (FTD) and related disorders [Coleman et al.: Alzheimer Dis Assoc Disord 2016;30:258-263]. Given attentional impairments in patients with FTD, whether and to what extent the abbreviated items on the MoCA may predict performance on corresponding assessments is not known...
February 16, 2017: Dementia and Geriatric Cognitive Disorders
https://www.readbyqxmd.com/read/28188757/cognitive-effects-of-androgen-deprivation-therapy-in-men-with-advanced-prostate-cancer
#6
Bulent Gunlusoy, Yasin Ceylan, Aslı Koskderlioglu, Muhtesem Gedizlioglu, Tansu Degirmenci, Pınar Ortan, Zafer Kozacioglu
OBJECTIVES: To evaluate prostate cancer effects of androgen deprivation therapy (ADT) by using a systematic set of methods to calculate specific cognitive functions in men with locally advanced or metastatic prostate cancer. METHODS: From April 2014 to February 2016, a prospective, comparative study was done to evaluate the cognitive effects of hormone therapy.Group 1 consisted of 78 patients with locally advanced or metastatic prostate cancer who received complete ADT treatment continously for 12 months and group 2 (control group) consisted of 78 patients who underwent radical prostatectomy without any additional treatment...
February 7, 2017: Urology
https://www.readbyqxmd.com/read/28177556/pattern-and-related-factors-of-cognitive-impairment-among-chronic-methamphetamine-users
#7
Tong-Yu Wang, Teng-Teng Fan, Yan-Ping Bao, Xiao-Dong Li, Chun-Mei Liang, Ru-Jia Wang, Jun Ma, Ying Han, Shi-Qiu Meng, Ping Wu, Jie Shi, Lin Lu
BACKGROUND AND OBJECTIVES: Methamphetamine (MA) use is increasingly prevalent in East and Southeast Asia and commonly associated with cognitive impairment. The present study estimated the characteristics of cognitive impairment and explored the associated potential factors among chronic MA users. METHODS: The data were from the baseline visit of a longitudinal study among synthetic drug users. The baseline survey was conducted in detoxification and rehabilitation centers in Guangdong province, China, from September to December in 2013...
February 8, 2017: American Journal on Addictions
https://www.readbyqxmd.com/read/28155182/italians-do-it-worse-montreal-cognitive-assessment-moca-optimal-cut-off-scores-for-people-with-probable-alzheimer-s-disease-and-with-probable-cognitive-impairment
#8
Andrea Bosco, Giuseppina Spano, Alessandro O Caffò, Antonella Lopez, Ignazio Grattagliano, Giuseppe Saracino, Katia Pinto, Frans Hoogeveen, Giulio E Lancioni
Montreal cognitive assessment (MoCA) is a test providing a brief screening for people with cognitive impairment due to aging or neurodegenerative syndromes. In Italy, as in the rest of the world, several validation studies of MoCA have been carried out. This study compared, for the first time in Italy, a sample of people with probable Alzheimer's Disease (AD) with healthy counterparts. The study also compared two community-dwelling groups of aged participants with and without probable cognitive impairment, as discriminated by two cut-off points of adjusted MMSE score...
February 2, 2017: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/28131163/the-test-accuracy-of-the-montreal-cognitive-assessment-moca-by-stroke-lateralisation
#9
Edgar Chan, Samantha Altendorff, Colm Healy, David J Werring, Lisa Cipolotti
BACKGROUND: The Montreal Cognitive Assessment (MoCA) is an increasingly popular screening tool for detecting cognitive impairment post-stroke. However its' test accuracy by stroke lateralisation is as yet unknown. AIM: Our aim was to investigate whether the test accuracy of the MoCA differs by stroke lateralisation across different cognitive domains. METHODS: We retrospectively examined the cognitive profiles of 228 subacute stroke patients (86 Left, 142 Right), comparing MoCA-total and domain-specific scores with performance on detailed neuropsychological assessment...
February 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28131162/resting-state-fmri-regional-homogeneity-correlates-with-cognition-measures-in-subcortical-vascular-cognitive-impairment
#10
Stefano Diciotti, Stefano Orsolini, Emilia Salvadori, Antonio Giorgio, Nicola Toschi, Stefano Ciulli, Andrea Ginestroni, Anna Poggesi, Nicola De Stefano, Leonardo Pantoni, Domenico Inzitari, Mario Mascalchi
BACKGROUND: The hyperintensity of cerebral white matter (WM) in T2-weighted MR images of elderly subjects due to small vessel disease (SVD) is associated with variable clinical features including mild cognitive impairment (MCI), also termed subcortical vascular cognitive impairment (SVCI). The latter is typically characterized by psychomotor slowing, attention deficits, and executive dysfunctions. We hypothesized that functional brain changes might be associated with these distinctive cognitive deficits in patients with SVCI...
February 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28125616/evaluating-the-effect-of-cognitive-dysfunction-on-mental-imagery-in-patients-with-stroke-using-temporal-congruence-and-the-imagined-timed-up-and-go-test-itug
#11
Maxime Geiger, Céline Bonnyaud, Yves-André Fery, Bernard Bussel, Nicolas Roche
BACKGROUND: Motor imagery (MI) capacity may be altered following stroke. MI is evaluated by measuring temporal congruence between the timed performance of an imagined and an executed task. Temporal congruence between imagined and physical gait-related activities has not been evaluated following stroke. Moreover, the effect of cognitive dysfunction on temporal congruence is not known. OBJECTIVE: To assess temporal congruence between the Timed Up and Go test (TUG) and the imagined TUG (iTUG) tests in patients with stroke and to investigate the role played by cognitive dysfunctions in changes in temporal congruence...
2017: PloS One
https://www.readbyqxmd.com/read/28123651/the-association-between-poor-sleep-quality-and-global-cortical-atrophy-is-related-to-age-results-from-the-atahualpa-project
#12
Oscar H Del Brutto, Robertino M Mera, Mauricio Zambrano, Pablo R Castillo
Community-dwellers aged ≥60 years enrolled in the Atahualpa Project underwent brain MRI and were interviewed with the Pittsburgh Sleep Quality Index. Of 290 participants, 94 (32%) had poor sleep quality and 143 (49%) had global cortical atrophy (GCA). In a logistic regression model (adjusted for demographics, cardiovascular risk factor, severe edentulism, symptoms of depression, the MoCA score, and neuroimaging signatures of cerebrovascular damage), poor sleep quality was associated with GCA (p=0.004). A multivariate probability model showed that the probability of moderate-to-severe GCA significantly increased in individuals with poor sleep quality aged ≥67 years...
July 2016: Sleep Science
https://www.readbyqxmd.com/read/28122474/screening-for-neurocognitive-impairment-in-hiv-positive-adults-aged-50-years-and-older-montreal-cognitive-assessment-relates-to-self-reported-and-clinician-rated-everyday-functioning
#13
P L Fazeli, K B Casaletto, E Paolillo, R C Moore, D J Moore, The Hnrp Group
As the HIV+ population ages, the risk for and need to screen for HIV-associated neurocognitive disorders (HAND) increases. The aim of this study is to determine the utility and ecological validity of the Montreal Cognitive Assessment (MoCA) among older HIV+ adults. A total of 100 HIV+ older adults aged 50 years or over completed a comprehensive neuromedical and neurocognitive battery, including the MoCA and several everyday functioning measures. The receiver operating characteristic curve indicates ≤26 as the optimal cut-off balancing sensitivity (84...
January 26, 2017: Journal of Clinical and Experimental Neuropsychology
https://www.readbyqxmd.com/read/28118690/poststroke-qeeg-informs-early-prognostication-of-cognitive-impairment
#14
Emma Schleiger, Andrew Wong, Stephen Read, Tennille Rowland, Simon Finnigan
Cognitive impairment is a common consequence of stroke, but remains difficult to predict. We investigate the ability of early QEEG assessment to inform such prediction, using binary logistic regression. Thirty-five patients (12 female, ages 18-87) suffering middle cerebral artery, ischemic stroke were studied. Resting-state EEG was recorded 48-239 h after symptom onset. Relative power for delta, theta, alpha, and beta bands, delta:alpha ratio, and peak alpha frequency were analyzed. Montreal Cognitive Assessment (MoCA) was administered, where possible, on day of EEG and at median 99 days (range 69-138) poststroke...
February 2017: Psychophysiology
https://www.readbyqxmd.com/read/28117613/relation-between-serum%C3%A2-leptin%C3%A2-levels-lipid-profiles-%C3%A2-and-neurocognitive-deficits-in-chinese-osahs-patients
#15
Yating Peng, Li Zhou, Yuping Cao, Ping Chen, Yan Chen, Dandan Zong, Ruoyun Ouyang
Objective The aim of this study was to compare serum leptin, apolipoprotein A1 (ApoA1), apolipoprotein J (ApoJ), and apolipoprotein H (ApoH) levels in males with obstructive sleep apnea and hypopnea syndrome (OSAHS) to those in healthy control subjects and to examine the possible relation between neurocognitive performance and these factors/serum markers in the subjects. Methods In this observational, cross-sectional study, a full-night polysomnography and sensitive neuropsychological assessment were performed on 50 newly diagnosed Chinese male patients and 30 healthy subjects...
January 24, 2017: International Journal of Neuroscience
https://www.readbyqxmd.com/read/28108207/cognitive-impairment-is-very-common-in-elderly-patients-with-syncope-and-unexplained-falls
#16
Susanne C de Ruiter, Jos F M de Jonghe, Tjeerd Germans, Jaap H Ruiter, René W M M Jansen
OBJECTIVES: To evaluate the prevalence of cognitive impairment (CI), including mild CI and dementia, in elderly patients with syncope and unexplained falls. In this population, we compared the use of the Mini-Mental State Examination (MMSE) with a cognitive screening test that assesses executive dysfunction typical of subcortical (vascular) CI, that is, the Montreal Cognitive Assessment (MoCA). DESIGN: Observational cohort study. SETTING: Outpatient fall and syncope clinic...
January 17, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/28041652/abnormal-spontaneous-brain-activity-in-type-2-diabetic-retinopathy-revealed-by-amplitude-of-low-frequency-fluctuations-a-resting-state-fmri-study
#17
Z-L Wang, L Zou, Z-W Lu, X-Q Xie, Z-Z Jia, C-J Pan, G-X Zhang, X-M Ge
AIM: To explore the altered spontaneous cerebral activity patterns and impaired functional regions in patients with diabetic retinopathy (DR) using resting-state functional magnetic resonance imaging (rs-fMRI) based on the amplitude of low-frequency fluctuations (ALFF) algorithm. MATERIALS AND METHODS: Twenty-one patients with DR (mean age, 54.9±9.9 years; 11 females) and 17 healthy control subjects (54.8±5.7 years; 9 females) were prospectively studied. The DR patients underwent laboratory tests...
December 29, 2016: Clinical Radiology
https://www.readbyqxmd.com/read/28039795/visuomotor-adaptability-in-older-adults-with-mild-cognitive-decline
#18
Jeffrey Schaffert, Chi-Mei Lee, Rebecca Neill, Jin Bo
The current study examined the augmentation of error feedback on visuomotor adaptability in older adults with varying degrees of cognitive decline (assessed by the Montreal Cognitive Assessment; MoCA). Twenty-three participants performed a center-out computerized visuomotor adaptation task when the visual feedback of their hand movement error was presented in a regular (ratio=1:1) or enhanced (ratio=1:2) error feedback schedule. Results showed that older adults with lower scores on the MoCA had less adaptability than those with higher MoCA scores during the regular feedback schedule...
February 2017: Acta Psychologica
https://www.readbyqxmd.com/read/28013571/short-montreal-cognitive-assessment
#19
A J Larner
The diagnostic accuracy of the short Montreal Cognitive Assessment (s-MoCA), a cognitive screening instrument recently derived by item response theory and computerized adaptive testing from the original MoCA, for the diagnosis of dementia and mild cognitive impairment (MCI) was assessed in 2 patient cohorts referred to a dedicated memory clinic in order to examine the validity and reproducibility of s-MoCA. Diagnosis used standard clinical diagnostic criteria for dementia and MCI as reference standard (prevalence of cognitive impairment = 0...
January 1, 2016: Journal of Geriatric Psychiatry and Neurology
https://www.readbyqxmd.com/read/28008314/cognitive-aging-and-the-hippocampus-in-older-adults
#20
Andrew O'Shea, Ronald A Cohen, Eric C Porges, Nicole R Nissim, Adam J Woods
The hippocampus is one of the most well studied structures in the human brain. While age-related decline in hippocampal volume is well documented, most of our knowledge about hippocampal structure-function relationships was discovered in the context of neurological and neurodegenerative diseases. The relationship between cognitive aging and hippocampal structure in the absence of disease remains relatively understudied. Furthermore, the few studies that have investigated the role of the hippocampus in cognitive aging have produced contradictory results...
2016: Frontiers in Aging Neuroscience
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