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https://www.readbyqxmd.com/read/28422847/correlation-between-calpain-10-single-nucleotide-polymorphisms-and-obstructive-sleep-apnea-hypopnoea-syndrome-with-ischemic-stroke-in-a-chinese-population-a-population-based-study
#1
Wei Zhang, Zhi-Ru Zhao, Chang-Fei Dai, Rong Zhang, Jie Chen, Hui-Juan Tian, Yun-Long Wang, Ji-Hong Sun, Qiu-Fang Lian
BACKGROUND: Obstructive sleep apnea-hypopnea syndrome (OSAHS) is a common chronic disorder which is followed by various complications. Calpain-10 belongs to a commonly expressed member of the Calpain-like cysteine protease family, which acts as risk marker for some diseases. The purpose of this study is to elucidate correlation between Calpain-10 single-nucleotide polymorphisms (SNPs) and the incidence of OSAHS followed by ischemic stroke (IS). METHODS: OSAHS patients were divided as OSAHS + IS, OSAHS, and control groups, respectively...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28420985/mapping-dorsal-and-ventral-caudate-in-older-adults-method-and-validation
#2
Haiqing Huang, Peter T Nguyen, Nadine A Schwab, Jared J Tanner, Catherine C Price, Mingzhou Ding
The caudate nucleus plays important roles in cognition and affect. Depending on associated connectivity and function, the caudate can be further divided into dorsal and ventral aspects. Dorsal caudate, highly connected to dorsolateral prefrontal cortex (DLPFC), is implicated in executive function and working memory; ventral caudate, more interconnected with the limbic system, is implicated in affective functions such as pain processing. Clinically, certain brain disorders are known to differentially impact dorsal and ventral caudate...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/28419623/cognitive-component-of-psychomotor-retardation-in-unipolar-and-bipolar-depression-is-verbal-fluency-a-relevant-marker-impact-of-repetitive-transcranial-stimulation
#3
Véronique Thomas-Ollivier, Emmanuelle Foyer, Samuel Bulteau, Anne Pichot, Pierre Valriviere, Anne Sauvaget, Thibault Deschamps
AIMS: In the literature, psychomotor retardation (PMR) is increasingly highlighted as a relevant marker for depression. Currently, we chose to focus on the fluency capacities as an evaluation of the frontal lobes functioning to reach a better understanding of cognitive and neurobiological mechanisms involved in PMR in depression. The aims of this study were 1) to explore the cognitive component of PMR through the analysis of Verbal Fluency (VF) performance in unipolar and bipolar depression; 2) to examine whether a repetitive transcranial magnetic stimulation (rTMS) treatment can improve concomitantly the RPM and VF capacities, as a relevant marker characteristic of the cognitive component of PMR...
April 17, 2017: Psychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/28415018/internal-consistency-and-concurrent-validity-of-the-montreal-cognitive-assessment-in-individuals-with-major-depressive-disorder
#4
Manit Srisurapanont, Kanokkwan Eurviriyanukul, Sirijit Suttajit, Pairada Varnado
This study aimed to determine the internal consistency and concurrent validity of the Montreal Cognitive Assessment (MoCA), as well as its subtests, in patients with major depressive disorder (MDD). Participants were patients with DSM-IV MDD aged between 21 and 65 years. Neurocognitive function was assessed by using the MoCA and 12 neurocognitive tests. The composite z-score of 12 neurocognitive tests, which indicated the global cognitive performance, was calculated. Participants were 57 outpatients with MDD...
April 6, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28412979/physical-exercise-for-late-life-depression-effects-on-cognition-and-disability
#5
Francesca Neviani, Martino Belvederi Murri, Chiara Mussi, Federico Triolo, Giulio Toni, Elisabetta Simoncini, Ferdinando Tripi, Marco Menchetti, Silvia Ferrari, Graziano Ceresini, Alessandro Cremonini, Marco Bertolotti, Giovanni Neri, Salvatore Squatrito, Mario Amore, Stamatula Zanetidou, Mirco Neri
BACKGROUND: Late-life depression is often associated with cognitive impairments and disability, which may persist even after adequate antidepressant drug treatment. Physical exercise is increasingly recognized as an effective antidepressant agent, and may exert positive effects on these features too. However, few studies examined this issue, especially by comparing different types of exercises. METHODS: We performed secondary analyses on data from the Safety and Efficacy of Exercise for Depression in Seniors study, a trial comparing the antidepressant effectiveness of sertraline (S), sertraline plus thrice-weekly non-progressive exercise (S+NPE), and sertraline plus thrice-weekly progressive aerobic exercise (S+PAE)...
April 17, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/28412051/-impact-of-postoperative-cognitive-decline-in-quality-of-life-a-prospective-study
#6
Joana Borges, Joana Moreira, Adriano Moreira, Alice Santos, Fernando J Abelha
BACKGROUND: Regardless the progress in perioperative care postoperative cognitive decline (PCD) has been accepted unequivocally as a significant and frequent complication of surgery in older patients. The aim of this study was to evaluate the incidence of postoperative cognitive decline and its influence on quality of life three months after surgery. METHODS: Observational, prospective study in a Post-Anesthesia Care Unit (PACU) in patients aged above 45 years, after elective major surgery...
April 12, 2017: Revista Brasileira de Anestesiologia
https://www.readbyqxmd.com/read/28409842/development-of-cognitive-screening-test-for-the-severely-hearing-impaired-hearing-impaired-moca
#7
Vincent Y W Lin, Janet Chung, Brandy L Callahan, Leah Smith, Nils Gritters, Joseph M Chen, Sandra E Black, Mario Masellis
OBJECTIVES: To develop a version of the Montreal Cognitive Assessment (MoCA) to be administered to the severely hearing impaired (HI-MoCA), and to assess its performance in two groups of cognitively intact adults over the age of 60. STUDY TYPE: Test development followed by prospective subject recruitment. METHODS: The MoCA was converted into a timed PowerPoint (Microsoft Corp., Redmond, WA) presentation, and verbal instructions were converted into visual instructions...
May 2017: Laryngoscope
https://www.readbyqxmd.com/read/28384640/comparative-diagnostic-accuracy-of-the-ace-iii-mis-mmse-moca-and-rudas-for-screening-of-alzheimer-disease
#8
Jordi A Matías-Guiu, María Valles-Salgado, Teresa Rognoni, Frank Hamre-Gil, Teresa Moreno-Ramos, Jorge Matías-Guiu
BACKGROUND: Our aim was to evaluate and compare the diagnostic properties of 5 screening tests for the diagnosis of mild Alzheimer disease (AD). METHODS: We conducted a prospective and cross-sectional study of 92 patients with mild AD and of 68 healthy controls from our Department of Neurology. The diagnostic properties of the following tests were compared: Mini-Mental State Examination (MMSE), Addenbrooke's Cognitive Examination III (ACE-III), Memory Impairment Screen (MIS), Montreal Cognitive Assessment (MoCA), and Rowland Universal Dementia Assessment Scale (RUDAS)...
April 7, 2017: Dementia and Geriatric Cognitive Disorders
https://www.readbyqxmd.com/read/28376127/the-doc-screen-feasible-and-valid-screening-for-depression-obstructive-sleep-apnea-osa-and-cognitive-impairment-in-stroke-prevention-clinics
#9
Richard H Swartz, Megan L Cayley, Krista L Lanctôt, Brian J Murray, Ashley Cohen, Kevin E Thorpe, Michelle N Sicard, Karen Lien, Demetrios J Sahlas, Nathan Herrmann
BACKGROUND: Post-stroke Depression, Obstructive sleep apnea (OSA) and Cognitive impairment ("DOC") are associated with greater mortality, worse recovery and poorer quality of life. Best practice recommendations endorse routine screening for each condition; yet, all are under-assessed, diagnosed and treated. We seek to determine the feasibility and validity of an integrated tool ("DOC" screen) to identify stroke clinic patients at high-risk of depression, OSA, and cognitive impairment...
2017: PloS One
https://www.readbyqxmd.com/read/28373801/serum-leptin-levels-and-cognition-in-parkinson-s-disease-patients
#10
Gülay Kenangil, Betül Özdilek
INTRODUCTION: To investigate the relationship between serum leptin levels and cognition in Parkinson's disease (PD) patients. METHODS: Thirty patients with idiopathic PD and 30 healthy controls were enrolled. At baseline, all patients had their standing height, weight, and waist circumference measurements taken using a standard scale. Their body mass index was then calculated. A fasting blood of 5 ml was obtained from each patient in the morning. ELISA was used to analyze leptin concentrations...
September 2016: Noro Psikiyatri Arsivi
https://www.readbyqxmd.com/read/28367173/cognitive-dysfunction-in-patients-with-systemic-lupus-erythematosus
#11
Bilal Azeem Butt, Sumaira Farman, Saira Elaine Anwer Khan, Muhammad Ahmed Saeed, Nighat Mir Ahmad
OBJECTIVE: To determine the frequency of cognitive dysfunction in patients with Systemic Lupus Erythematosus in a Pakistani population, presenting at a tertiary care Rheumatology setting. METHODS: This cross-sectional study was conducted at the Division of Rheumatology, Fatima Memorial Hospital, Lahore, from March to June 2016. A total of 43 consecutive patients, who fulfilled the 2012 SLICC (Systemic Lupus International Collaborating Clinics) classification criteria for Systemic Lupus Erythematosus (SLE), were enrolled...
January 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/28366772/pupillary-response-to-cognitive-workload-during-saccadic-tasks-in-parkinson-s-disease
#12
M Ranchet, J Orlosky, J Morgan, S Qadir, A E Akinwuntan, H Devos
The relationship between cognitive workload and cognitive impairments in Parkinson's disease (PD) is currently not well known. This study compared cognitive workload during saccadic tasks between patients with PD and controls. Sixteen controls, 11 patients with no obvious cognitive impairment (PD-NCI) (MOCA score≥26), and 10 PD patients with cognitive impairment (PD-CI) (MOCA score<26) performed prosaccade and antisaccade tasks. Cognitive workload, extracted via pupil recording, and other eye metrics were compared between the three groups...
March 31, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28365749/montreal-cognitive-assessment-performance-among-community-dwelling-african-americans
#13
Heidi C Rossetti, Laura H Lacritz, Linda S Hynan, C Munro Cullum, Aaron Van Wright, Myron F Weiner
Objective: To report descriptive and normative data for the Montreal Cognitive Assessment (MoCA) in a population-based African American sample. Method: The MoCA was administered to 1,419 African American participants (mean age 49.89 years, range 18-75, 64% female). After excluding those with subjective cognitive complaints (n = 301), normative data were generated by education and overlapping age ranges (n = 1,118). Pearson correlations and analysis of variance were used to examine the relationship to demographic variables, and frequency of missed items was reviewed...
March 1, 2017: Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists
https://www.readbyqxmd.com/read/28364958/validation-of-the-spanish-language-version-of-the-montreal-cognitive-assessment-test-in-adults-older-than-60-years
#14
C Delgado, A Araneda, M I Behrens
INTRODUCTION: Few studies have validated the Spanish-language version of the Montreal Cognitive Assessment (MoCA-S) test in Latin American populations. OBJETIVE: To evaluate the psychometric properties and discriminant validity of the MoCA-S in elderly patients in Santiago de Chile. METHODS: 172 individuals were grouped according to their clinical diagnosis based on the Clinical Dementia Rating (CDR) scale as follows: amnestic mild cognitive impairment (aMCI; n±24), non-amnestic MCI (naMCI; n±24), mild dementia (n±20), and cognitively normal (n±104)...
March 30, 2017: Neurología: Publicación Oficial de la Sociedad Española de Neurología
https://www.readbyqxmd.com/read/28351200/diagnostic-accuracy-and-confidence-in-the-clinical-detection-of-cognitive-impairment-in-early-stage-parkinson-disease
#15
Kathryn A Wyman-Chick, Phillip K Martin, Matthew J Barrett, Carol A Manning, Scott A Sperling
BACKGROUND/AIMS: Mild cognitive impairment (MCI) is present in up to 34% of patients with early-stage Parkinson disease (PD); however, it is difficult to detect subtle impairment without objective cognitive testing. METHODS: Data were obtained from the Parkinson Progression Marker Initiative. All 341 participants were administered the Montreal Cognitive Assessment (MoCA) and a brief neuropsychological battery. Participants were classified as PD-MCI if MoCA was <26 or if they scored ≥1 standard deviation below the normative mean in 2 or more domains, based upon established criteria...
January 1, 2017: Journal of Geriatric Psychiatry and Neurology
https://www.readbyqxmd.com/read/28346831/anxiety-and-depression-as-longitudinal-predictors-of-mild-cognitive-impairment-in-older-adults
#16
Antônio Carlos Cruz Freire, Milena Pereira Pondé, Aihua Liu, Jean Caron
INTRODUCTION: Few studies have dealt with the potential correlation between anxiety, depression, and cognitive impairment in community-dwelling older adults. METHOD: This longitudinal study was conducted in the city of Montreal, Canada, with 352 older adults aged 55 years or more. The participants were interviewed at baseline and again 2 years later. The Montreal Cognitive Assessment (MoCA) score was estimated and compared between the 2 time points, the Composite International Diagnostic Interview (CIDI) was used to assess major depression and anxiety, and the K10 measured high psychological distress...
January 1, 2017: Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie
https://www.readbyqxmd.com/read/28346532/decline-in-changing-montreal-cognitive-assessment-moca-scores-is-associated-with-post-stroke-cognitive-decline-determined-by-a-formal-neuropsychological-evaluation
#17
Hui Hui Tan, Jing Xu, Hock Luen Teoh, Bernard Poon-Lap Chan, Raymond Chee Seong Seet, Narayanaswarmy Venketasubramanian, Vijay Kumar Sharma, Christopher Li-Hsian Chen, YanHong Dong
OBJECTIVES: We aimed to examine changes in the Montreal Cognitive Assessment (MoCA) and Mini-Mental State Examination (MMSE) scores within a one-year period after stroke/transient ischemic attack (TIA) in associating cognitive decline determined by a formal neuropsychological test battery. METHODS: Patients with ischemic stroke/TIA received MoCA and MMSE at baseline within 14 days after stroke/TIA, at 3-6 months and 1-year follow-ups. The scores of MoCA and MMSE were considered to have declined if there were a reduction of ≥2 points in the respective scores measured across two time points...
2017: PloS One
https://www.readbyqxmd.com/read/28338380/the-association-between-physical-activity-with-cognitive-function-and-brain-derived-neurotrophic-factor-in-people-with-parkinson-s-disease-a-pilot-study
#18
Hanan Khalil, Mahmoud A Alomari, Omar Khabour, Aya Al-Hieshan, Jawad A Bajwa
OBJECTIVE: To examine the effect of physical capacity, on the relationship of Brain-Derived Neurotrophic Factor (BDNF) with cognitive function in people with PD. METHODS: Serum BDNF levels were measured in 29 PD participants and 30 healthy controls. Cognitive function was assessed using the Montreal Cognitive Assessment (MOCA) scale. Physical capacity was evaluated using the six minute walk distance (6-MWD). Participants were categorized into low or high physical capacity group according to their 50(th) percentile 6-MWD...
March 24, 2017: Journal of Aging and Physical Activity
https://www.readbyqxmd.com/read/28336349/decisional-capacity-for-advanced-care-directives-in-parkinson-s-disease-with-cognitive-concerns
#19
Muneer Abu Snineh, Richard Camicioli, Janis M Miyasaki
INTRODUCTION: Physician Orders for Life Sustaining Therapies (POLST) or Goals of Care (GOC) are legal documents to guide intensity of interventions (ICU, resuscitation, hospitalization or comfort care) completed by healthcare professionals following counseling of patients or their designated medical decision makers. Capacity (understanding, appreciation, reasoning and expressing a choice) to consent to POLST or GOC has not been determined among Parkinson's disease (PD) patients. We sought to assess GOC PD decisional capacity for those with cognitive complaints but not dementia...
March 8, 2017: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/28333925/video-based-educational-intervention-associated-with-improved-stroke-literacy-self-efficacy-and-patient-satisfaction
#20
Mary Carter Denny, Farhaan Vahidy, Kim Y T Vu, Anjail Z Sharrief, Sean I Savitz
BACKGROUND AND PURPOSE: Interventions are needed to improve stroke literacy among recent stroke survivors. We developed an educational video for patients hospitalized with acute ischemic stroke (AIS) and intracerebral hemorrhage (ICH). METHODS: A 5-minute stroke education video was shown to our AIS and ICH patients admitted from March to June 2015. Demographics and a 5-minute protocol Montreal Cognitive Assessment were also collected. Questions related to stroke knowledge, self-efficacy, and patient satisfaction were answered before, immediately after, and 30 days after the video...
2017: PloS One
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