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fidelity to the healing relationship

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https://www.readbyqxmd.com/read/27174082/an-ethnomedicinal-survey-of-a-tashelhit-speaking-community-in-the-high-atlas-morocco
#1
Irene Teixidor-Toneu, Gary J Martin, Ahmed Ouhammou, Rajindra K Puri, Julie A Hawkins
ETHNOPHARMACOLOGICAL RELEVANCE: Traditional knowledge about medicinal plants from a poorly studied region, the High Atlas in Morocco, is reported here for the first time; this permits consideration of efficacy and safety of current practises whilst highlighting species previously not known to have traditional medicinal use. AIM OF THE STUDY: Our study aims to document local medicinal plant knowledge among Tashelhit speaking communities through ethnobotanical survey, identifying preferred species and new medicinal plant citations and illuminating the relationship between emic and etic ailment classifications...
July 21, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/25384535/detailed-profiling-of-anti-desmoglein-autoantibodies-identifies-anti-dsg1-reactivity-as-a-key-driver-of-disease-activity-and-clinical-expression-in-pemphigus-vulgaris
#2
S Y Naseer, K Seiffert-Sinha, A A Sinha
With their near-universal presence in patients and ease of clinical measurement, anti-desmoglein (Dsg) antibodies serve as primary candidates for creating prognostic tools in Pemphigus vulgaris (PV). Although the desmoglein compensation hypothesis postulates a clear relationship between anti-Dsg autoantibodies and clinical phenotype in PV, recent studies have questioned the fidelity of this hypothesis as a predictor of lesion morphology. Moreover, few studies address the association of anti-Dsg antibodies to other clinical parameters such as disease phase and age at onset...
June 2015: Autoimmunity
https://www.readbyqxmd.com/read/25015221/fidelity-to-the-healing-relationship-a-medical-student-s-challenge-to-contemporary-bioethics-and-prescription-for-medical-practice
#3
Blake C Corcoran, Lea Brandt, David A Fleming, Chris N Gu
As a medical  student, I observed that different physicians had strikingly different attitudes and approaches when caring for patients. The care of one patient in particular continues to challenge my understanding of illness and moral responsibility in the practice of medicine. In this paper, I illustrate the care of this patient in order to evaluate the dominant ethics I was taught in medical school, in theory and in practice, and argue neither principlism nor the ethics of care fully captures the moral responsibility of physicians...
April 2016: Journal of Medical Ethics
https://www.readbyqxmd.com/read/23590235/high-affinity-dna-base-analogs-as-supramolecular-nanoscale-promoters-of-macroscopic-adhesion
#4
Cyrus A Anderson, Amanda R Jones, Ellen M Briggs, Eric J Novitsky, Darrell W Kuykendall, Nancy R Sottos, Steven C Zimmerman
Adhesion phenomena are essential to many biological processes and to synthetic adhesives and manufactured coatings and composites. Supramolecular interactions are often implicated in various adhesion mechanisms. Recently, supramolecular building blocks, such as synthetic DNA base-pair mimics, have drawn attention in the context of molecular recognition, self-assembly, and supramolecular polymers. These reversible, hydrogen-bonding interactions have been studied extensively for their adhesive capabilities at the nano- and microscale, however, much less is known about their utility for practical adhesion in macroscopic systems...
May 15, 2013: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/23516442/compound-ex-vivo-and-in-silico-method-for-hemodynamic-analysis-of-stented-arteries
#5
Farhad Rikhtegar, Fernando Pacheco, Christophe Wyss, Kathryn S Stok, Heng Ge, Ryan J Choo, Aldo Ferrari, Dimos Poulikakos, Ralph Müller, Vartan Kurtcuoglu
Hemodynamic factors such as low wall shear stress have been shown to influence endothelial healing and atherogenesis in stent-free vessels. However, in stented vessels, a reliable quantitative analysis of such relations has not been possible due to the lack of a suitable method for the accurate acquisition of blood flow. The objective of this work was to develop a method for the precise reconstruction of hemodynamics and quantification of wall shear stress in stented vessels. We have developed such a method that can be applied to vessels stented in or ex vivo and processed ex vivo...
2013: PloS One
https://www.readbyqxmd.com/read/21504725/in-chemotaxing-fibroblasts-both-high-fidelity-and-weakly-biased-cell-movements-track-the-localization-of-pi3k-signaling
#6
Adam T Melvin, Erik S Welf, Yana Wang, Darrell J Irvine, Jason M Haugh
Cell movement biased by a chemical gradient, or chemotaxis, coordinates the recruitment of cells and collective migration of cell populations. During wound healing, chemotaxis of fibroblasts is stimulated by platelet-derived growth factor (PDGF) and certain other chemoattractants. Whereas the immediate PDGF gradient sensing response has been characterized previously at the level of phosphoinositide 3-kinase (PI3K) signaling, the sensitivity of the response at the level of cell migration bias has not yet been studied quantitatively...
April 20, 2011: Biophysical Journal
https://www.readbyqxmd.com/read/21375959/venus-iii-a-randomised-controlled-trial-of-therapeutic-ultrasound-in-the-management-of-venous-leg-ulcers
#7
RANDOMIZED CONTROLLED TRIAL
J M Watson, A R Kang'ombe, M O Soares, L-H Chuang, G Worthy, J M Bland, C Iglesias, N Cullum, D Torgerson, E A Nelson
OBJECTIVES: To compare the clinical effectiveness and cost-effectiveness of low-dose ultrasound delivered in conjunction with standard care against standard care alone in the treatment of hard-to-heal venous ulcers. DESIGN: A multicentre, pragmatic, two-armed randomised controlled trial with an economic evaluation. SETTING: Community nurse services; community leg ulcer clinics; hospital outpatient leg ulcer clinics, among both urban and rural settings in England, Scotland, Northern Ireland and Ireland...
March 2011: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/20488233/antihypertensive-activity-of-salvia-elegans-vahl-lamiaceae-ace-inhibition-and-angiotensin-ii-antagonism
#8
Enrique Jiménez-Ferrer, Fidel Hernández Badillo, Manases González-Cortazar, Jaime Tortoriello, Maribel Herrera-Ruiz
ETHNOPHARMACOLOGICAL RELEVANCE: Salvia elegans Vahl. (Lamiaceae), recognized with the popular name of "mirto" is widely used in Mexico for healing purposes, and also them as antihypertensive treatment. AIM OF THE STUDY: The high prevalence of this illness and the side effects of antihypertensive drugs conducted us to the evaluation of the Salvia elegans extract on angiotensin II action. MATERIALS AND METHODS: The acute response of blood pressure to angiotensin II administration was measured in mice...
July 20, 2010: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/20051095/intra-lesional-injections-of-recombinant-human-epidermal-growth-factor-promote-granulation-and-healing-in-advanced-diabetic-foot-ulcers-multicenter-randomised-placebo-controlled-double-blind-study
#9
RANDOMIZED CONTROLLED TRIAL
José I Fernández-Montequín, Carmen M Valenzuela-Silva, Odalys González Díaz, William Savigne, Natasha Sancho-Soutelo, Fidel Rivero-Fernández, Pablo Sánchez-Penton, Lourdes Morejón-Vega, Heriberto Artaza-Sanz, Arístides García-Herrera, Cecilio González-Benavides, Carlos M Hernández-Cañete, Alberto Vázquez-Proenza, Jorge Berlanga-Acosta, Pedro A López-Saura
A multicenter, double-blind, placebo-controlled trial was carried out to evaluate the intra-lesional infiltration of recombinant epidermal growth factor (EGF) in Wagner's grade 3 or 4 diabetic foot ulcers (DFUs). Subjects (149) were randomised to receive EGF (75 or 25 microg) or placebo, three times per week for 8 weeks and standard good wound care. The main endpoint was granulation tissue covering > or = 50% of the ulcer at 2 weeks. It was achieved by 19/48 controls versus 44/53 in the 75 microg group [odds ratio (OR): 7...
December 2009: International Wound Journal
https://www.readbyqxmd.com/read/16613085/-psychological-repercussion-of-the-scars-in-the-burned-patient
#10
Alonso José María Argüello, Kinori Sara Guila Fidel, Josep M Petit Jornet, Xavier Teixidó Vidal
The scars produced by burns have serious consequences for the patient. The repercussions go further than the discomfort, pain and physical restrictions, going as far as causing significant psychological consequences which can restrict the personal and social relationships of those affected. From the accounts told by two burn victims, and the technical analysis carried out by psychologists and psychiatrists specialised in this field, we gain a better understanding of the situation of these patients, on the basis of which we propose a series of nursing interventions designed to improve the care given in the area of wound healing...
March 2006: Revista de Enfermería
https://www.readbyqxmd.com/read/11889747/walking-the-hmo-balance
#11
S M Gallagher
Fidelity is the ethical obligation to act in good faith to keep promises, fulfill agreements, and maintain relationships and fiduciary responsibilities. Consumers are increasingly interested in the balance between the fiscal viability of our current healthcare delivery system and the system's reason for existence--that is, to serve the health needs of clients. Escalating healthcare costs have driven many institutions and third party payors to examine service and payment practices. Some consumers and consumer rights groups contend that these evolving practices threaten the very essence of health and healthcare...
March 2001: Ostomy/wound Management
https://www.readbyqxmd.com/read/10630584/adaptive-role-of-caloric-intake-on-the-degenerative-disease-processes
#12
REVIEW
R W Hart, R Dixit, J Seng, A Turturro, J E Leakey, R Feuers, P Duffy, C Buffington, G Cowan, S Lewis, J Pipkin, S Y Li
Carcinogenicity and aging are characterized by a set of complex endpoints, which appear as a series of molecular events. Many of these events can be modified by caloric intake. Since most of these processes determine an organism's ability to cope with various environmental stressors, it is not surprising that a relationship (in the presence of a constant nutrient density) exists between caloric intake and time-to-tumor and/or life span. Our studies have clearly shown that generally, the greater the caloric intake, the greater the body weight, the higher the incidence of spontaneous tumor occurrence, the greater the susceptibility to chemical carcinogens, and the shorter the life span...
December 1999: Toxicological Sciences: An Official Journal of the Society of Toxicology
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