Thomas M Raffay, Juliann M Di Fiore, Zhengyi Chen, Ángel Sánchez-Illana, Maximo Vento, José David Piñeiro-Ramos, Julia Kuligowski, Richard J Martin, Curtis Tatsuoka, Nori M Minich, Peter M MacFarlane, Anna Maria Hibbs
BACKGROUND: Intermittent hypoxemia (IH) events are common in preterm neonates and are associated with adverse outcomes. Animal IH models can induce oxidative stress. We hypothesized that an association exists between IH and elevated peroxidation products in preterm neonates. METHODS: Time in hypoxemia, frequency of IH, and duration of IH events were assessed from a prospective cohort of 170 neonates (<31 weeks gestation). Urine was collected at 1 week and 1 month...
May 15, 2023: Pediatric Research