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JOURNAL ARTICLE
Lyndsay M O'Hara, Anthony D Harris, David P Calfee, Graham M Snyder, James Cottam, Nathan N O'Hara, Elise M Martin
"All or none" approaches to the use of contact precautions for methicillin-resistant Staphylococcus aureus (MRSA) both fail to recognize that transmission risk varies. This qualitative study assessed healthcare personnel perspectives regarding the feasibility of a risk-tailored approach to use contact precautions for MRSA more strategically in the acute care setting.
April 22, 2024: Infection Control and Hospital Epidemiology
#2
JOURNAL ARTICLE
HyungSeon Kim, Dongwon Choi, Haeun Shim, Kyeong-Yae Sohng, Min-Jung Choi
OBJECTIVES: This study aimed to assess the educational needs and analyze the priorities of infection prevention and control (IPC) for community-visiting nurses. DESIGN: This is a cross-sectional descriptive study. SAMPLE: This study was conducted with 144 visiting nurses working in public health centers and long-term care facilities in South Korea. METHOD: A total of 23 questions in five subcategories were used to measure the current knowledge and perceived importance of IPC in community-visiting nursing...
April 16, 2024: Public Health Nursing
#3
JOURNAL ARTICLE
Majid M Alshamrani, Aiman El-Saed, Mohammed Al Zunitan, Mohammed Abalkhail, Doris Abagguey, Fayssal M Farahat
BACKGROUND: A widely-accepted standardized preventive bundle targeting multidrug-resistant organisms (MDROs) is lacking. The objective was to describe the components, implementation, compliance, and impact of a novel MDROs bundle in intensive care units (ICUs). METHODS: Cohort study of surveillance activities on the components of MDROs bundle (July 2019 to June 2022) and the incidence of MDROs (April 2016 to June 2022). The implementation of MDROs bundle were preceded by ICPs-led education of the staff working in target ICUs about the importance and components of the MDROs bundle...
April 15, 2024: Heliyon
#4
JOURNAL ARTICLE
Gabrielle M Gussin, James A McKinnell, Raveena D Singh, Loren G Miller, Ken Kleinman, Raheeb Saavedra, Thomas Tjoa, Shruti K Gohil, Tabitha D Catuna, Lauren T Heim, Justin Chang, Marlene Estevez, Jiayi He, Kathleen O'Donnell, Matthew Zahn, Eunjung Lee, Chase Berman, Jenny Nguyen, Shalini Agrawal, Isabel Ashbaugh, Christine Nedelcu, Philip A Robinson, Steven Tam, Steven Park, Kaye D Evans, Julie A Shimabukuro, Bruce Y Lee, Emily Fonda, John A Jernigan, Rachel B Slayton, Nimalie D Stone, Lynn Janssen, Robert A Weinstein, Mary K Hayden, Michael Y Lin, Ellena M Peterson, Cassiana E Bittencourt, Susan S Huang
IMPORTANCE: Infections due to multidrug-resistant organisms (MDROs) are associated with increased morbidity, mortality, length of hospitalization, and health care costs. Regional interventions may be advantageous in mitigating MDROs and associated infections. OBJECTIVE: To evaluate whether implementation of a decolonization collaborative is associated with reduced regional MDRO prevalence, incident clinical cultures, infection-related hospitalizations, costs, and deaths...
April 1, 2024: JAMA
#5
JOURNAL ARTICLE
Carmit Katz, Noa Cohen, Afnan Attrash-Najjar, Talia Glucklich, Ma'ayan Jacobson, Natalia Varela, Sidnei Rinaldo Priolo-Filho, Olivia D Chang, Sadiyya Haffejee, David Kaawa-Mafigiri, Ilan Katz, Kathryn Maguire-Jack, Nadia Massarweh, George M Tarabulsy, Diane Thembekile Levine, Christine Wekerle
BACKGROUND: The COVID-19 pandemic created new challenges and barriers for the work of child protection professionals (CPPs) and intensified existing hardships for families and children, increasing the risk of child maltreatment. As new restrictions and precautions were implemented by governments worldwide to stop the virus from spreading, CPPs had to adapt to a new reality of working remotely. However, limited research has investigated how remote work impacted CPPs and child protection work and how CPPs handled this alternative work style...
March 27, 2024: Child Abuse & Neglect
#6
JOURNAL ARTICLE
Nicholas A Turner, Jay Krishnan, Alicia Nelson, Christopher R Polage, Ronda L Sinkowitz-Cochran, Lucy Fike, David T Kuhar, Preeta K Kutty, Rachel L Snyder, Deverick J Anderson
IMPORTANCE: Despite modest reductions in the incidence of hospital-onset Clostridioides difficile infection (HO-CDI), CDI remains a leading cause of health care-associated infection. As no single intervention has proven highly effective on its own, a multifaceted approach to controlling HO-CDI is needed. OBJECTIVE: To assess the effectiveness of the Centers for Disease Control and Prevention's Strategies to Prevent Clostridioides difficile Infection in Acute Care Facilities Framework (hereafter, the Framework) in reducing HO-CDI incidence...
March 4, 2024: JAMA Network Open
#7
JOURNAL ARTICLE
Soyeon Park, Seongman Bae, Eun Ok Kim, Euijin Chang, Min Jae Kim, Yong Pil Chong, Sang-Ho Choi, Sang-Oh Lee, Yang Soo Kim, Jiwon Jung, Sung-Han Kim
OBJECTIVES: There is limited data on the effects of discontinuing single-room isolation while maintaining contact precautions, such as the use of gowns and gloves. In April 2021, our hospital ceased single-room isolation for patients with VRE because of single-room unavailability. This study assessed the impact of this policy by examining the incidence of hospital-acquired VRE bloodstream infections (HA-VRE BSI). METHODS: This retrospective quasi-experimental study was conducted at a tertiary care hospital in Seoul, South Korea...
March 14, 2024: Journal of Hospital Infection
#8
JOURNAL ARTICLE
Carranza A, Chueca N, De Salazar A, Peña A, Yuste E, García F, Colmenero M
In ICU settings, screening patients upon admission for potential multiresistant bacteria (BMR) carriers is crucial. Traditionally, clinical decisions relied on delayed culture results, but a rapid PCR molecular test called RealCycler-Rezero-U/G (Progenie-molecular©), emerged as an alternative. This study aimed to validate its effectiveness in detecting gram-negative BMR in rectal swabs at ICU admission. Over 24 months, an observational study was conducted on 1,234 admitted patients, with 217 meeting isolation criteria and undergoing both PCR and culture tests...
March 8, 2024: Diagnostic Microbiology and Infectious Disease
#9
Kavya Prasad, Brian E Serencsits, Bae P Chu, Lawrence T Dauer, Maria Donzelli, Ellen Basu, Kim Kramer, Neeta Pandit-Taskar
Background Radiolabeled antibody 131 I-omburtamab was administered intraventricularly in patients with leptomeningeal disease under an institutionally approved study (# NCT03275402 ). Radiation safety precautions were tailored for individual patients, enabling outpatient treatment based on in-depth, evidence-based recommendations for such precautions. The imperative advancement of streamlined therapeutic administration procedures, eliminating the necessity for inpatient isolation and resource-intensive measures, holds pivotal significance...
February 28, 2024: Research Square
#10
JOURNAL ARTICLE
Pamela Bailey, Kaila Cooper, Michael P Stevens, Gonzalo Bearman, Michelle Doll
In an identified quality improvement effort, nurses were observed regarding their workflow while in contact precaution rooms. Multiple opportunities for hand hygiene were missed while nurses were in gloves, predominantly while moving between "dirty" and "clean" tasks. An education initiative afterward did not show improvement in hand hygiene rates.
February 29, 2024: Infection Control and Hospital Epidemiology
#11
JOURNAL ARTICLE
Durbar Roy, Saptarshi Basu
Non-contact tonometry (NCT) is a non-invasive ophthalmologic technique to measure intraocular pressure (IOP) using an air puff for routine glaucoma testing. Although IOP measurement using NCT has been perfected over many years, various phenomenological aspects of interfacial physics, fluid structure interaction, waves on corneal surface, and pathogen transmission routes to name a few are inherently unexplored. Research investigating the interdisciplinary physics of the ocular biointerface and of the NCT procedure is sparse and hence remains to be explored in sufficient depth...
January 1, 2024: Biointerphases
#12
JOURNAL ARTICLE
Jiaming Cui, Jack Heavey, Leo Lin, Eili Y Klein, Gregory R Madden, Costi D Sifri, Bryan Lewis, Anil K Vullikanti, B Aditya Prakash
OBJECTIVE: To evaluate the economic costs of reducing the University of Virginia Hospital's present "3-negative" policy, which continues methicillin-resistant Staphylococcus aureus (MRSA) contact precautions until patients receive 3 consecutive negative test results, to either 2 or 1 negative. DESIGN: Cost-effective analysis. SETTINGS: The University of Virginia Hospital. PATIENTS: The study included data from 41,216 patients from 2015 to 2019...
February 26, 2024: Infection Control and Hospital Epidemiology
#13
JOURNAL ARTICLE
Guilherme Amaral Calvet, Edna Kara, Lianne Gonsalves, Armando Humberto Seuc, Raquel de Vasconcellos Carvalhaes de Oliveira, Soe Soe Thwin, Rodolfo Gomez Ponce de León, Maité Cabrera Gámez, Gilda Monteagudo Peña, Bertha Victoria Rodríguez Pendás, Manuel Gómez Alzugaray, Gisel Ovies Carballo, Duniesky Cintra Cala, Patrícia Machado Quintaes Guimarães, Mercedes Bonet, Melanie Taylor, Anna Thorson, Caron Kim, Moazzam Ali, Nathalie Broutet
OBJECTIVE: To identify and summarise the evidence on the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA detection and persistence in body fluids associated with sexual activity (saliva, semen, vaginal secretion, urine and faeces/rectal secretion). ELIGIBILITY: All studies that reported detection of SARS-CoV-2 in saliva, semen, vaginal secretion, urine and faeces/rectal swabs. INFORMATION SOURCES: The WHO COVID-19 database from inception to 20 April 2022...
February 21, 2024: BMJ Open
#14
JOURNAL ARTICLE
Lauren T Shapiro, Adriana Valbuena Valecillos, Regina McDade, Rossana M Rosa, Lilian M Abbo
Candida auris is a highly transmissible yeast that is capable of causing invasive and fatal infections, particularly among persons with underlying medical conditions. Its incidence is rising, especially among patients cared for in post-acute care facilities. Individuals colonized with the yeast may be cared for in inpatient rehabilitation settings, without heightened risk for invasive infection and/or transmission to others, as long as appropriate infection control measures are followed. This article reviews key information for rehabilitation nurses caring for persons with C...
February 16, 2024: Rehabilitation Nursing: the Official Journal of the Association of Rehabilitation Nurses
#15
Stephanie S Johnson, Katelin C Jackson, Eric T Lofgren
OBJECTIVES: To ascertain if faculty and staff were the link between the two COVID-19 outbreaks in a rural university county, and if the local university's COVID-19 policies affected contact rates of their employees across all its campuses. METHODS: We conducted two anonymous, voluntary online surveys for faculty and staff of a PAC-12 university on their contact patterns both within and outside the university during the COVID-19 pandemic. One was asked when classes were virtual, and another when classes were in-person but masking...
February 8, 2024: medRxiv
#16
JOURNAL ARTICLE
Hyeonji Seo, Seowoo Kim, Yun Woo Lee, Hong Sang Oh, Han-Sung Kim, Yong Kyun Kim
OBJECTIVES: The aims of this study were to evaluate the impact of the result of a subsequent polymerase chain reaction (PCR) test for carbapenemase after serial negative surveillance cultures on positive culture conversion in patients with three consecutive negative surveillance cultures for carbapenemase-producing Enterobacterales (CPE), and to identify risk factors for conversion. METHODS: We performed a retrospective study of patients with positive CPE cultures on CHROMagar KPC medium in a tertiary hospital in Korea from October 2018 to December 2022...
February 16, 2024: Journal of Hospital Infection
#17
JOURNAL ARTICLE
Gillean Kelly, Marisa Hudson, Bridget Apple, Debora Bundage, Bradley Lembcke, Todd Lasco, Mayar Al Mohajer
Variations in the literature support the benefit of contact precautions for methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE) infections in the hospital setting. During personal protective equipment shortages throughout the COVID-19 pandemic, contact precautions were discontinued for MRSA and VRE-infected patients. Rates of hospital-acquired MRSA and VRE infections were compared before and after this intervention, along with hand hygiene proportions. Contact precaution discontinuation did not lead to an increase in hospital-acquired MRSA or VRE infections...
March 2024: Journal of Infection Prevention
#18
JOURNAL ARTICLE
Jessica R Howard-Anderson, Lindsey B Gottlieb, Susan E Beekmann, Philip M Polgreen, Jesse T Jacob, Daniel Z Uslan
OBJECTIVE: To understand how healthcare facilities employ contact precautions for patients with multidrug-resistant organisms (MDROs) in the post-coronavirus disease 2019 (COVID-19) era and explore changes since 2014. DESIGN: Cross-sectional survey. PARTICIPANTS: Emerging Infections Network (EIN) physicians involved in infection prevention or hospital epidemiology. METHODS: In September 2022, we sent via email an 8-question survey on contact precautions and adjunctive measures to reduce MDRO transmission in inpatient facilities...
February 14, 2024: Infection Control and Hospital Epidemiology
#19
JOURNAL ARTICLE
Andreana Angelova, Mariya Atanasova, Kostadin Ketev, Zeyra Halil, Ivanka Paskaleva, Gergana Lengerova, Teodora Dimcheva, Neli Korsun, Mariana Murdjeva
The Coronavirus Disease 2019 (COVID-19) caused by a novel coronavirus (SARS-CoV-2) affects mainly older adults. Those with comorbidities are at a higher risk of severe disease and even death. The symptomatic infection rate of children is lower, manifestations are milder, and severe forms are scarce. We present here two children with severe COVID-19 and a respiratory syncytial virus, with the goal of emphasizing the possibility of coinfection with a severe course and a different result. The microbiological diagnosis was made using multiplex PCR...
June 30, 2023: Folia Medica
#20
JOURNAL ARTICLE
Genomic surveillance of Clostridioides difficile transmission and virulence in a healthcare setting.
Erin P Newcomer, Skye R S Fishbein, Kailun Zhang, Tiffany Hink, Kimberly A Reske, Candice Cass, Zainab H Iqbal, Emily L Struttmann, Carey-Ann D Burnham, Erik R Dubberke, Gautam Dantas
Clostridioides difficile infection (CDI) is a major cause of healthcare-associated diarrhea, despite the widespread implementation of contact precautions for patients with CDI. Here, we investigate strain contamination in a hospital setting and the genomic determinants of disease outcomes. Across two wards over 6 months, we selectively cultured C. difficile from patients ( n = 384) and their environments. Whole-genome sequencing (WGS) of 146 isolates revealed that most C. difficile isolates were from clade 1 (131/146, 89...
February 8, 2024: MBio
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