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https://www.readbyqxmd.com/read/27915096/universal-contact-precautions-do-not-change-the-prevalence-of-antibiotic-resistant-organisms-in-a-tertiary-burn-unit
#1
Adelyn L Ho, Reid Chambers, Claudia Malic, Anthony Papp
OBJECTIVE: The prevalence of antibiotic-resistant organisms (ARO) in burn units is increasing worldwide and contributes significantly to morbidity and mortality. Study aims are to describe the burden of AROs in burn patients admitted to a tertiary burn unit, to evaluate the impact of contact precautions implemented after an outbreak of antibiotic-resistant Acinetobacter baumannii, and to identify possible predictors of ARO acquisition. METHODS: Data of burn inpatients between 2006 and 2010 were retrospectively reviewed...
November 30, 2016: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/27905620/-the-water-supply-of-a-pediatric-hospital-as-a-possible-source-of-an-outbreak-of-diarrhea-due-to-microsporidium-spp-in-immunocompromised-patients
#2
Paulina Coria, Claudia Urízar, Andrea Alba, Isabel Noemí, Anita Pino, José Luis Cerva
INTRODUCTION: The hospital water supply is a reservoir of a variety of potentially pathogenic microorganisms that can particularly affect children and immunocompromised patients. Potentially pathogenic Microsporidium spp. have been identified in water. Microsporidiosis is an emerging parasitic and opportunistic infection in immunocompromised patients. OBJECTIVE AND METHOD: to describe an outbreak of nosocomial diarrhea due to Microsporidium, species Encephalitozoon intestinalis...
August 2016: Revista Chilena de Infectología: órgano Oficial de la Sociedad Chilena de Infectología
https://www.readbyqxmd.com/read/27890687/revisiting-sports-precautions-in-children-with-solitary-kidneys-and-cakut-congenital-anomalies-of-the-kidney-and-urinary-tract
#3
REVIEW
Dimitri Papagiannopoulos, Edward Gong
This review article explores sports and recreational precautions in children with solitary kidneys. In 2001, the American Academy of Pediatrics published recommendations for activity in children with medical conditions. Those with solitary kidneys were graded a "qualified yes": no restriction in non-contact sports, and individual assessment for limited-contact, contact, and collision sports. Recent trauma data suggests that classification according to degree of contact is inaccurate. We propose an updated, data-driven classification of sports/recreation according to risk of high-grade renal trauma or loss of renal unit...
November 24, 2016: Urology
https://www.readbyqxmd.com/read/27890334/control-of-carbapenemase-producing-enterobacteriaceae-outbreaks-in-acute-settings-an-evidence-review
#4
REVIEW
C E French, C Coope, L Conway, J P T Higgins, J McCulloch, G Okoli, B C Patel, I Oliver
BACKGROUND: In recent years, infections with carbapenemase-producing Enterobacteriaceae (CPE) have been increasing globally and present a major public health challenge. AIM: To review the international literature: (i) to describe CPE outbreaks in acute hospital settings globally; and (ii) to identify the control measures used during these outbreaks and report on their effectiveness. METHODS: A systematic search of MEDLINE and EMBASE databases, abstract lists for key conferences and reference lists of key reviews was undertaken, and information on unpublished outbreaks was sought for 2000-2015...
October 14, 2016: Journal of Hospital Infection
https://www.readbyqxmd.com/read/27876971/isolation-of-acanthamoeba-spp-from-different-water-sources-in-isfahan-central-iran-2014
#5
Reza Mohammadi Manesh, Maryam Niyyati, Hossein Ali Yousefi, Abbas Ali Eskandarian
Acanthamoeba spp. are free-living amoeba found in a wide variety of natural habitats. The high percentage of the presence of Acanthamoeba in different environmental sources represents a sanitary risk for public health, especially immunocompromised patients and contact lens wearers. Acanthamoeba can cause granulomatous amoebic encephalitis, otitis, lung lesions, and skin infections in individuals with immune deficiencies. In the present study, the status of contamination of water sources in Isfahan, central Iran is analyzed through parasitological method...
December 2016: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/27828002/an-integrated-intervention-for-increasing-clinical-nurses-knowledge-of-hiv-aids-related-occupational-safety
#6
Liping He, Zhiyan Lu, Jing Huang, Yiping Zhou, Jian Huang, Yongyi Bi, Jun Li
Background: Approximately 35 new HIV (Human Immunodeficiency Virus, HIV) cases and at least 1000 serious infections are transmitted annually to health care workers. In China, HIV prevalence is increasing and nursing personnel are encountering these individuals more than in the past. Contaminated needle-stick injuries represent a significant occupational burden for nurses. Evidence suggests that nurses in China may not fully understand HIV/AIDS (Acquired immunodeficiency syndrome, AIDS) and HIV-related occupational safety...
November 7, 2016: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/27821198/electronic-clostridium-difficile-infection-bundle-reduces-time-to-initiation-of-contact-precautions
#7
Courtney M Dewart, Natalia Blanco, Betsy Foxman, Anurag N Malani
The impact of computerized order-entry bundles on timing of contact precaution initiation for C. difficile infection (CDI) remains largely unexplored. Implementation of an electronic CDI prevention and management bundle that included an automatic isolation component significantly reduced time to initiation of contact precautions from 33.7 to 22.4 hours. Infect Control Hosp Epidemiol 2016;1-3.
November 8, 2016: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/27817759/status-of-the-prevention-of-multidrug-resistant-organisms-in-international-settings-a-survey-of-the-society-for-healthcare-epidemiology-of-america-research-network
#8
Nasia Safdar, Sharmila Sengupta, Jackson S Musuuza, Manisha Juthani-Mehta, Marci Drees, Lilian M Abbo, Aaron M Milstone, Jon P Furuno, Meera Varman, Deverick J Anderson, Daniel J Morgan, Loren G Miller, Graham M Snyder
OBJECTIVE To examine self-reported practices and policies to reduce infection and transmission of multidrug-resistant organisms (MDRO) in healthcare settings outside the United States. DESIGN Cross-sectional survey. PARTICIPANTS International members of the Society for Healthcare Epidemiology of America (SHEA) Research Network. METHODS Electronic survey of infection control and prevention practices, capabilities, and barriers outside the United States and Canada. Participants were stratified according to their country's economic development status as defined by the World Bank as low-income, lower-middle-income, upper-middle-income, and high-income...
November 7, 2016: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/27752880/the-effect-of-hospital-isolation-precautions-on-patient-outcomes-and-cost-of-care-a-multi-site-retrospective-propensity-score-matched-cohort-study
#9
Kim Tran, Chaim Bell, Nathan Stall, George Tomlinson, Allison McGeer, Andrew Morris, Michael Gardam, Howard B Abrams
BACKGROUND: Isolation precautions have negative effects on patient safety, psychological well-being, and healthcare worker contact. However, it is not known whether isolation precautions affect certain hospital-related outcomes. OBJECTIVE: To examine the effect of isolation precautions on hospital-related outcomes and cost of care. DESIGN: Retrospective, propensity-score matched cohort study of inpatients admitted to general internal medicine (GIM) services at three academic hospitals in Toronto, Ontario, Canada between January 2010 and December 2012...
October 17, 2016: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/27746394/counting-the-cost-of-an-outbreak-of-carbapenemase-producing-enterobacteriaceae-an-economic-evaluation-from-a-hospital-perspective
#10
Jonathan A Otter, Philip Burgess, Frances Davies, Siddharth Mookerjee, Julie Singleton, Mark Gilchrist, Darren Parsons, Eimear T Brannigan, Julie Robotham, Alison H Holmes
OBJECTIVE: To perform an economic evaluation on the cost associated with an outbreak of carbapenemase-producing Enterobacteriaceae (CPE). METHODS: We performed an observational economic evaluation of an outbreak of CPE (NDM-producing Klebsiella pneumoniae) affecting 40 patients in a group of five hospitals across three sites in West London. Costs were split into actual expenditure (including anti-infective costs, enhanced CPE screening, contact precautions, temporary ward-based monitors of hand and environmental practice, and environmental decontamination), and 'opportunity cost' (staff time, bed closures, and elective surgical missed revenue)...
October 13, 2016: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/27726900/first-nosocomial-outbreak-of-vana-type-vancomycin-resistant-enterococcus-raffinosus-in-france
#11
S Jolivet, M Fines-Guyon, B Nebbad, J C Merle, D Le Pluart, C Brun-Buisson, J-W Decousser, V Cattoir
BACKGROUND: Vancomycin-resistant Enterococcus raffinosus has rarely been associated with nosocomial infection and outbreaks. AIM: To report the successful control of a nosocomial outbreak of vanA-type vancomycin-resistant E. raffinosus in a surgical intensive care unit. METHODS: The investigation of the outbreak is reported with control measures taken. Molecular typing of vancomycin-resistant E. raffinosus isolates was performed by repetitive sequence-based polymerase chain reaction (PCR)...
December 2016: Journal of Hospital Infection
https://www.readbyqxmd.com/read/27707423/impact-of-ultraviolet-germicidal-irradiation-for-no-touch-terminal-room-disinfection-on-clostridium-difficile-infection-incidence-among-hematology-oncology-patients
#12
David A Pegues, Jennifer Han, Cheryl Gilmar, Brooke McDonnell, Steven Gaynes
OBJECTIVE To evaluate the impact of no-touch terminal room no-touch disinfection using ultraviolet wavelength C germicidal irradiation (UVGI) on C. difficile infection (CDI) rates on inpatient units with persistently high rates of CDI despite infection control measures. DESIGN Interrupted time-series analysis with a comparison arm. SETTING 3 adult hematology-oncology units in a large, tertiary-care hospital. METHODS We conducted a 12-month prospective valuation of UVGI. Rooms of patients with CDI or on contact precautions were targeted for UVGI upon discharge using an electronic patient flow system...
October 6, 2016: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/27703336/profile-of-the-capsaicin-8-patch-for-the-management-of-neuropathic-pain-associated-with-postherpetic-neuralgia-safety-efficacy-and-patient-acceptability
#13
Muhammad Laklouk, Ganesan Baranidharan
Capsaicin is a naturally occurring irritant active ingredient found in hot peppers. It is a ligand for transient receptor potential channel vanilloid receptors, which are found in nociceptive nerve terminals in the skin. Initial exposure to topical capsaicin leads to excitation of these receptors, release of vasoactive mediators, erythema, intense burning, pain, and thereafter desensitization of sensory neurons resulting in inhibition of pain transmission. Capsaicin 8% has been licensed for the treatment of postherpetic neuralgia pain in recent years...
2016: Patient Preference and Adherence
https://www.readbyqxmd.com/read/27686257/nosocomial-herpes-simplex-encephalitis-a-challenging-diagnosis
#14
Hussein Algahtani, Bader Shirah, Mohammed Hmoud, Ahmad Subahi
Herpes simplex encephalitis (HSE) is a rare disease, but it is the most common form of sporadic encephalitis. HSE is transmitted through direct contact and developing nosocomial HSE is rarely reported in the literature. Nosocomial HSE is difficult to diagnose due to its non-specific clinical features. In this article, we present a case of nosocomial HSE that was responsible for grave consequence. We also explore its causes, outcome, and give recommendations to avoid such fatal occurrence. We stress on strict adherence to the standard precautions and preventive control measures...
September 24, 2016: Journal of Infection and Public Health
https://www.readbyqxmd.com/read/27668762/control-of-infectious-mortality-due-to-carbapenemase-producing-klebsiella-pneumoniae-in-hematopoietic-stem-cell-transplantation
#15
A Forcina, R Baldan, V Marasco, P Cichero, A Bondanza, M Noviello, S Piemontese, C Soliman, R Greco, F Lorentino, F Giglio, C Messina, M Carrabba, M Bernardi, J Peccatori, M Moro, A Biancardi, P Nizzero, P Scarpellini, D M Cirillo, N Mancini, C Corti, M Clementi, F Ciceri
Carbapenemase-producing Klebsiella pneumoniae (KPC-Kp) infections are an emerging cause of death after hematopoietic stem cell transplantation (HSCT). In allogeneic transplants, mortality rate may rise up to 60%. We retrospectively evaluated 540 patients receiving a transplant from an auto- or an allogeneic source between January 2011 and October 2015. After an Institutional increase in the prevalence of KPC-Kp bloodstream infections (BSI) in June 2012, from July 2012, 366 consecutive patients received the following preventive measures: (i) weekly rectal swabs for surveillance; (ii) contact precautions in carriers (iii) early-targeted therapy in neutropenic febrile carriers...
September 26, 2016: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/27660091/vancomycin-resistant-enterococci-epidemiology-infection-prevention-and-control
#16
Katherine Reyes, Ana Cecilia Bardossy, Marcus Zervos
Vancomycin-resistant enterococci (VRE) infections have acquired prominence as a leading cause of health care-associated infections. Understanding VRE epidemiology, transmission modes in health care settings, risk factors for colonization, and infection is essential to prevention and control of VRE infections. Infection control strategies are pivotal in management of VRE infections and should be based on patient characteristics, hospital needs, and available resources. Hand hygiene is basic to decrease acquisition of VRE...
September 19, 2016: Infectious Disease Clinics of North America
https://www.readbyqxmd.com/read/27660089/prevention-of-infection-due-to-clostridium-difficile
#17
Christopher C Cooper, Robin L P Jump, Teena Chopra
Clostridium difficile is one of the foremost nosocomial pathogens. Preventing infection is particularly challenging. Effective prevention efforts typically require a multifaceted bundled approach. A variety of infection control procedures may be advantageous, including strict hand decontamination with soap and water, contact precautions, and using chlorine-containing decontamination agents. Additionally, risk factor reduction can help reduce the burden of disease. The risk factor modification is principally accomplished though antibiotic stewardship programs...
September 19, 2016: Infectious Disease Clinics of North America
https://www.readbyqxmd.com/read/27647097/participation-in-a-mentored-quality-improvement-program-for-insulin-pen-safety-opportunity-to-augment-internal-evaluation-and-share-with-peers
#18
Amy F Rosenberg
PURPOSE: UF Health's participation in a mentored quality-improvement impact program for health professionals as part of an ASHP initiative-"Strategies for Ensuring the Safe Use of Insulin Pens in the Hospital"-is described. SUMMARY: ASHP invited hospitals to participate in its initiative at a time when UF Health was evaluating the risks and benefits of insulin pen use due to external reports of safety concerns and making a commitment to continue insulin pen use and optimize safeguards...
October 1, 2016: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/27638794/risk-assessment-of-pbdes-and-pahs-in-house-dust-in-kocaeli-turkey-levels-and-sources
#19
Mihriban Yılmaz Civan, U Merve Kara
Indoor dust samples were collected from 40 homes in Kocaeli, Turkey and were analyzed simultaneously for 14 polybrominated diphenyl ethers (PBDEs) and 16 poly aromatic hydrocarbons (PAHs) isomers. The total concentrations of PBDEs (Σ14PBDEs) ranged from 29.32 to 4790 ng g(-1), with a median of 316.1 ng g(-1), while the total indoor dust concentrations of 16 PAHs (Σ16PAHs) extending over three to four orders of magnitude ranged from 85.91 to 40,359 ng g(-1) with a median value of 2489 ng g(-1). Although deca-PBDE products (BDE-209) were the principal source of PBDEs contamination in the homes (median, 138...
December 2016: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/27619507/assessment-of-the-overall-and-multidrug-resistant-organism-bioburden-on-environmental-surfaces-in-healthcare-facilities
#20
Alicia M Shams, Laura J Rose, Jonathan R Edwards, Salvatore Cali, Anthony D Harris, Jesse T Jacob, Anna LaFae, Lisa L Pineles, Kerri A Thom, L Clifford McDonald, Matthew J Arduino, Judith A Noble-Wang
OBJECTIVE To determine the typical microbial bioburden (overall bacterial and multidrug-resistant organisms [MDROs]) on high-touch healthcare environmental surfaces after routine or terminal cleaning. DESIGN Prospective 2.5-year microbiological survey of large surface areas (>1,000 cm2). SETTING MDRO contact-precaution rooms from 9 acute-care hospitals and 2 long-term care facilities in 4 states. PARTICIPANTS Samples from 166 rooms (113 routine cleaned and 53 terminal cleaned rooms). METHODS Using a standard sponge-wipe sampling protocol, 2 composite samples were collected from each room; a third sample was collected from each Clostridium difficile room...
December 2016: Infection Control and Hospital Epidemiology
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