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https://www.readbyqxmd.com/read/28431174/opportunities-for-exercise-during-pullet-rearing-part-ii-long-term-effects-on-bone-characteristics-of-adult-laying-hens-at-the-end-of-lay
#1
T M Casey-Trott, D R Korver, M T Guerin, V Sandilands, S Torrey, T M Widowski
Osteoporosis in laying hens has been a production and welfare concern for several decades. The objective of this study was to determine whether differing opportunities for exercise during pullet rearing influences long-term bone quality characteristics in end-of-lay hens. A secondary objective was to assess whether differing opportunities for exercise in adult housing systems alters bone quality characteristics in end-of-lay hens. Four flock replicates of 588 Lohmann Selected Leghorn-Lite pullets were reared in either conventional cages (Conv) or an aviary rearing system (Avi) and placed into conventional cages (CC), 30-bird furnished cages (FC-S), or 60-bird furnished cages (FC-L) for adult housing...
April 18, 2017: Poultry Science
https://www.readbyqxmd.com/read/28430811/antimicrobial-resistance-in-coagulase-positive-staphylococci-isolated-from-companion-animals-in-australia-a-one-year-study
#2
Sugiyono Saputra, David Jordan, Kate A Worthing, Jacqueline M Norris, Hui S Wong, Rebecca Abraham, Darren J Trott, Sam Abraham
Methicillin-resistant coagulase-positive staphylococci (CoPS) have become increasingly recognised as opportunistic pathogens that limit therapeutic options in companion animals. The frequency of methicillin resistance amongst clinical isolates on an Australia-wide level is unknown. This study determined antimicrobial susceptibility patterns for CoPS isolated from clinical infections in companion animals (dogs, cats and horses) as part of the first nation-wide survey on antimicrobial resistance in animal pathogens in Australia for a one-year period (January 2013 to January 2014)...
2017: PloS One
https://www.readbyqxmd.com/read/28422439/does-touch-inhibit-visual-imagery-a-case-study-on-acquired-blindness
#3
Jana von Trott Zu Solz, Marco Paolini, Sarita Silveira
In a single-case study of acquired blindness, differential brain activation patterns for visual imagery of familiar objects with and without tactile exploration as well as of tactilely explored unfamiliar objects were observed. Results provide new insight into retrieval of visual images from episodic memory and point toward a potential tactile inhibition of visual imagery.
April 19, 2017: PsyCh Journal
https://www.readbyqxmd.com/read/28394397/development-of-perching-behavior-in-3-strains-of-pullets-reared-in-furnished-cages
#4
A M Habinski, L J Caston, T M Casey-Trott, M E Hunniford, T M Widowski
Furnished rearing cages are becoming more widely available to replace conventional systems for pullets. To date, there is little information on how pullets develop perching behavior in furnished cages or how this varies among strains. The objective of this study was to evaluate the use of perches and a platform in a commercial furnished rearing "Combi-Cage" system by 3 pure-bred heritage strains of pullets (Rhode Island Red, Columbian Rock, and White Leghorn). Each cage had 4 elevated locations: one platform and 3 perches of differing heights and positions in the cage...
March 1, 2017: Poultry Science
https://www.readbyqxmd.com/read/28390264/selected-life-extending-interventions-reduce-arterial-cxcl10-and-macrophage-colony-stimulating-factor-in-aged-mouse-arteries
#5
Daniel W Trott, Lisa A Lesniewski, Anthony J Donato
Cardiovascular disease (CVD) is the leading cause of death in the industrialized world. Aging is the most predictive risk factor for CVD and is associated with arterial inflammation which contributes to increased CVD risk. Although age-related arterial inflammation has been described in both humans and animals, only a limited number of inflammatory mediators, cytokines and chemokines have been identified. In this investigation we sought to determine whether lifespan extending interventions, including crowded litter early life nutrient deprivation (CL), traditional lifelong caloric restriction (CR) and lifelong Rapamycin treatment (Rap) would attenuate age-related arterial inflammation using multi analyte profiling...
April 5, 2017: Cytokine
https://www.readbyqxmd.com/read/28379533/opportunities-for-exercise-during-pullet-rearing-part-i-effect-on-the-musculoskeletal-characteristics-of-pullets
#6
T M Casey-Trott, D R Korver, M T Guerin, V Sandilands, S Torrey, T M Widowski
Increased load-bearing exercise improves bone quality characteristics in a variety of species, including laying hens. Providing increased opportunities for exercise during the pullet rearing phase, a period of substantial musculoskeletal growth, offers a proactive approach to reducing osteoporosis by improving bone composition. The main objective of this study was to determine whether differing opportunities for exercise during rearing influences pullet musculoskeletal characteristics. Two flock replicates of 588 Lohmann Selected Leghorn-Lite pullets were reared in either standard, conventional cages (Conv) or an aviary rearing system (Avi) from day-old chicks until 16 wk of age...
March 31, 2017: Poultry Science
https://www.readbyqxmd.com/read/28371938/rearing-system-affects-prevalence-of-keel-bone-damage-in-laying-hens-a-longitudinal-study-of-four-consecutive-flocks
#7
T M Casey-Trott, M T Guerin, V Sandilands, S Torrey, T M Widowski
High flock-level prevalence of keel-bone fractures and deviations in laying hens are commonly reported across various housing systems; however, few longitudinal studies exist, especially for furnished and conventional cage systems. Load-bearing exercise improves bone strength and mineral composition in laying hens and has the potential to reduce keel-bone damage, especially if exercise is allowed during critical periods of bone growth throughout the pullet rearing phase. The objective of this study was to determine the prevalence of keel-bone damage in laying hens housed in furnished and conventional cages, and assess whether opportunities for exercise during the pullet rearing phase influenced the prevalence of keel-bone damage throughout the laying period...
March 21, 2017: Poultry Science
https://www.readbyqxmd.com/read/28370511/di-zinc-aryl-complexes-co2-insertions-and-applications-in-polymerization-catalysis
#8
Charles Romain, Jennifer A Garden, Gemma Trott, Antoine Buchard, Andrew J P White, Charlotte Katherine Williams
Two new di-zinc aryl complexes, [LZn2Ph2] and [LZn2(C6F5)2], coordinated by a diphenol tetraamine macrocyclic ligand are prepared and fully characterized, including by single crystal X-ray diffraction experiments. The complexes' reactivities with monomers including carbon dioxide, cyclohexene oxide, phthalic anhydride, iso-propanol and phenol are investigated using both experimental studies and density functional theory calculations. In particular, [LZn2Ph2] readily inserts carbon dioxide to form a carboxylate, at 1 bar pressure, whereas [LZn2(C6F5)2] does not react...
March 30, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28328413/oliver-scott-1922-2016
#9
Klaus R Trott
No abstract text is available yet for this article.
December 2016: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/28166200/upregulation-of-marcks-in-kidney-cancer-and-its-potential-as-a-therapeutic-target
#10
C-H Chen, L W R Fong, E Yu, R Wu, J F Trott, R H Weiss
Targeted therapeutics, such as those abrogating hypoxia inducible factor (HIF)/vascular endothelial growth factor signaling, are initially effective against kidney cancer (or renal cell carcinoma, RCC); however, drug resistance frequently occurs via subsequent activation of alternative pathways. Through genome-scale integrated analysis of the HIF-α network, we identified the major protein kinase C substrate MARCKS (myristoylated alanine-rich C kinase substrate) as a potential target molecule for kidney cancer...
February 6, 2017: Oncogene
https://www.readbyqxmd.com/read/28074319/trans-fatty-acid-stimulated-mammary-gland-growth-in-ovariectomized-mice-is-fatty-acid-type-and-isomer-specific
#11
Grace E Berryhill, Susan G Miszewski, Josephine F Trott, Jana Kraft, Adam L Lock, Russell C Hovey
We previously reported that the trans-18:2 fatty acid trans-10, cis-12 conjugated linoleic acid (t10,c12-CLA) stimulates mammary gland development independent of estrogen and its receptor. Given the negative consequences of dietary trans-fatty acids on various aspects of human health, we sought to establish whether other trans-fatty acids could similarly induce ovary-independent mammary gland growth in mice. Prepubertal BALB/cJ mice were ovariectomized at 21 days of age then were fed diets enriched with cis-9, trans-11 CLA (c9,t11-CLA), or mixtures of trans-18:1 fatty acids supplied by partially hydrogenated sunflower, safflower, or linseed oil...
March 2017: Lipids
https://www.readbyqxmd.com/read/28012941/age-related-arterial-immune-cell-infiltration-in-mice-is-attenuated-by-caloric-restriction-or-voluntary-exercise
#12
Daniel W Trott, Grant D Henson, Mi H T Ho, Sheilah A Allison, Lisa A Lesniewski, Anthony J Donato
Age-related arterial inflammation is associated with dysfunction of the arteries and increased risk for cardiovascular disease. To determine if aging increases arterial immune cell infiltration as well as the populations of immune cells principally involved, we tested the hypothesis that large elastic and resistance arteries in old mice would exhibit increased immune cell infiltration compared to young controls. Additionally, we hypothesized that vasoprotective lifestyle interventions such as lifelong caloric restriction or 8weeks of voluntary wheel running would attenuate age-related arterial immune cell infiltration...
December 22, 2016: Experimental Gerontology
https://www.readbyqxmd.com/read/27914637/redo-thoracoabdominal-aortic-aneurysm-repair-a-single-center-experience-over-25%C3%A2-years
#13
Rana O Afifi, Harleen K Sandhu, Amy E Trott, Tom C Nguyen, Charles C Miller, Anthony L Estrera, Hazim J Safi
BACKGROUND: Aortic disease is a lifelong, progressive illness that may require repeated intervention over time. We reviewed our 25-year experience with open redo thoracoabdominal aortic aneurysm (TAAA) and descending thoracic aortic aneurysm (DTAA) repair. Our objectives were to determine patient outcomes after redo repair of DTAA/TAAA and compare them with nonredo repair. We also attempted to identify the risk factors for poor outcome. METHODS: We reviewed all open redo TAAA and DTAA repairs between 1991 and 2014...
November 30, 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27887889/development-of-intramammary-drug-delivery-systems-novel-in%C3%A2-vitro-release-method
#14
Sanjay Garg, Wen Wang, Yunmei Song, Patricia Eats, Darren J Trott, Stephen W Page, Kiro R Petrovski
The aim of this study was to develop an in vitro release model for intramammary drug delivery system (IMDS) evaluation. This study was the first to establish an in vitro-in vivo correlation with investigation of an IMDS containing lasalocid. Three different methods including the standard United States Pharmacopeia dissolution method with apparatus 2, a modified United States Pharmacopeia method using a dialysis bag, or a specifically designed enhancer cell system, were assessed for the release study. Full cream milk and water were selected as the release media...
November 23, 2016: Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/27873393/tributes-to-peter-alan-trott-mb-bchir-frcpath
#15
A McKinna, R Millis
No abstract text is available yet for this article.
December 2016: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/27842872/first-detection-of-extended-spectrum-cephalosporin-and-fluoroquinolone-resistant-escherichia-coli-in-australian-food-producing-animals
#16
Sam Abraham, David Jordan, Hui S Wong, James R Johnson, Mark A Toleman, David L Wakeham, David M Gordon, John D Turnidge, Joanne L Mollinger, Justine S Gibson, Darren J Trott
This study aimed to define the frequency of resistance to critically important antimicrobials (CIAs) [i.e. extended-spectrum cephalosporins (ESCs), fluoroquinolones (FQs) and carbapenems] among Escherichia coli isolates causing clinical disease in Australian food-producing animals. Clinical E. coli isolates (n=324) from Australian food-producing animals [cattle (n=169), porcine (n=114), poultry (n=32) and sheep (n=9)] were compiled from all veterinary diagnostic laboratories across Australia over a 1-year period...
December 2015: Journal of Global Antimicrobial Resistance
https://www.readbyqxmd.com/read/27785348/how-to-study-the-impact-of-sex-and-gender-in-medical-research-a-review-of-resources
#17
REVIEW
Alyson J McGregor, Memoona Hasnain, Kathryn Sandberg, Mary F Morrison, Michelle Berlin, Justina Trott
There is a growing appreciation by the biomedical community that studying the impact of sex and gender on health, aging, and disease will lead to improvements in human health. Sex- and gender-based comparisons can inform research on disease mechanisms and the development of new therapeutics as well as enhance scientific rigor and reproducibility. This review will assist basic researchers, clinical investigators, as well as epidemiologists, population, and social scientists by providing an annotated bibliography of currently available resource tools on how to consider sex and gender as independent variables in research design and methodology...
2016: Biology of Sex Differences
https://www.readbyqxmd.com/read/27767038/isolation-and-plasmid-characterization-of-carbapenemase-imp-4-producing-salmonella-enterica-typhimurium-from-cats
#18
Sam Abraham, Mark O'Dea, Darren J Trott, Rebecca J Abraham, David Hughes, Stanley Pang, Genevieve McKew, Elaine Y L Cheong, John Merlino, Sugiyono Saputra, Richard Malik, Thomas Gottlieb
Carbapenem-resistant Enterobacteriaceae (CRE) are a pressing public health issue due to limited therapeutic options to treat such infections. CREs have been predominantly isolated from humans and environmental samples and they are rarely reported among companion animals. In this study we report on the isolation and plasmid characterization of carbapenemase (IMP-4) producing Salmonella enterica Typhimurium from a companion animal. Carbapenemase-producing S. enterica Typhimurium carrying blaIMP-4 was identified from a systemically unwell (index) cat and three additional cats at an animal shelter...
October 21, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27671081/phenotypic-and-genotypic-profiling-of-antimicrobial-resistance-in-enteric-escherichia-coli-communities-isolated-from-finisher-pigs-in-australia
#19
M G Smith, D Jordan, J S Gibson, R N Cobbold, T A Chapman, S Abraham, D J Trott
OBJECTIVE: To assess herd-to-herd variation in antimicrobial resistance phenotypes and associated antimicrobial resistance genes (ARGs) in faecal commensal Escherichia coli communities isolated from Australian slaughter-age pigs. METHODS: Hydrophobic grid-membrane filtration (HGMF) was used to screen populations of E. coli isolated from faecal samples obtained from pigs prior to or at slaughter. Multiplex PCRs were applied to the pooled DNA extracted from the samples to identify specific ARGs...
October 2016: Australian Veterinary Journal
https://www.readbyqxmd.com/read/27666313/phylogenetic-diversity-antimicrobial-susceptibility-and-virulence-characteristics-of-phylogroup-f-escherichia-coli-in-australia
#20
Belinda Vangchhia, Sam Abraham, Jan M Bell, Peter Collignon, Justine S Gibson, Paul R Ingram, James R Johnson, Karina Kennedy, Darren J Trott, John D Turnidge, David M Gordon
Unlike Escherichia coli strains belonging to phylogroup B2, the clinical significance of strains belonging to phylogroup F is not well understood. Here we report on a collection of phylogroup F strains recovered in Australia from faeces and extra-intestinal sites from humans, companion animals and native animals, as well as from poultry meat and water samples. The distribution of sequence types was clearly non-random with respect to isolate source. The antimicrobial resistance and virulence trait profiles also varied with the sequence type of the isolate...
November 2016: Microbiology
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